Page last updated: 2024-08-24

zileuton and pyrilamine

zileuton has been researched along with pyrilamine in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's8 (72.73)18.2507
2000's1 (9.09)29.6817
2010's2 (18.18)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Augert, G; Cottin, M; Demonchaux, P; Dupassieux, P; Jasserand, D; Lenoir, P; Paris, D; Peck, MJ1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Bendele, AM; Fleisch, JH; Wong, WS1
Bochnowicz, S; Underwood, DC1
Buckner, CK; Conklin, R; Doran, O; Fishleder, RI; Graziano, FM; Will, JA1
Bell, RL; Brooks, DW; Carter, GW; Malo, PE; Shaughnessy, TK; Summers, JB1
Ellis, JL; Undem, BJ1
Frossard, N; LeGall, G; Poaty, V; Riquet, M1
Dahlén, SE; Larsson, L; Sydbom, A1
Arias, K; Baig, M; Chu, D; Colangelo, M; Coyle, A; Goncharova, S; Jordana, M; Vadas, P; Walker, T; Waserman, S1

Other Studies

11 other study(ies) available for zileuton and pyrilamine

ArticleYear
Synthesis, structure-activity relationships, and pharmacological evaluation of pyrrolo[3,2,1-ij]quinoline derivatives: potent histamine and platelet activating factor antagonism and 5-lipoxygenase inhibitory properties. Potential therapeutic application i
    Journal of medicinal chemistry, 1995, Feb-17, Volume: 38, Issue:4

    Topics: Animals; Asthma; Female; Guinea Pigs; Histamine Antagonists; In Vitro Techniques; Lipoxygenase Inhibitors; Male; Platelet Activating Factor; Platelet Aggregation Inhibitors; Quinolines; Rabbits; Rats; Rats, Sprague-Dawley; Respiratory Function Tests; Skin Tests; Structure-Activity Relationship

1995
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Pharmacologic evaluation of A23187-induced contractions of three distinct preparations of guinea pig lung parenchymal strips.
    The Journal of pharmacology and experimental therapeutics, 1992, Volume: 260, Issue:2

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Calcimycin; Drug Interactions; Guinea Pigs; Histamine; Hydroxyurea; In Vitro Techniques; Indomethacin; Lung; Male; Muscle Contraction; Muscle, Smooth; Prostaglandin Endoperoxides, Synthetic; Pyrilamine; SRS-A

1992
Dose-dependent mediation of leukotriene D4-induced airway microvascular leakage and bronchoconstriction in the guinea pig.
    Prostaglandins, leukotrienes, and essential fatty acids, 1995, Volume: 52, Issue:6

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Bridged Bicyclo Compounds, Heterocyclic; Bronchi; Bronchoconstriction; Capillary Permeability; Chromones; Fatty Acids, Unsaturated; Furans; Guinea Pigs; Hydrazines; Hydroxyurea; Leukotriene D4; Lipoxygenase Inhibitors; Lung; Male; Meclofenamic Acid; Plasma; Prostaglandin Endoperoxides, Synthetic; Pyrilamine; Receptors, Thromboxane; SRS-A; Thromboxane A2; Trachea; Vasoconstrictor Agents

1995
Pharmacologic modulation of the influence of the epithelium on immunologic- and nonimmunologic-induced histamine release and contraction in guinea pig superfused tracheal strips.
    The Journal of pharmacology and experimental therapeutics, 1993, Volume: 264, Issue:2

    Topics: Animals; Epithelium; Female; Guinea Pigs; Histamine Release; Hydroxyurea; In Vitro Techniques; Indazoles; Indomethacin; Muscle Contraction; Ovalbumin; Pyrilamine; Trachea; Tubocurarine

1993
The 5-lipoxygenase inhibitory activity of zileuton in in vitro and in vivo models of antigen-induced airway anaphylaxis.
    Pulmonary pharmacology, 1994, Volume: 7, Issue:2

    Topics: Anaphylaxis; Animals; Anti-Inflammatory Agents, Non-Steroidal; Bronchoconstriction; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Guinea Pigs; Humans; Hydroxyurea; Indazoles; Lipoxygenase Inhibitors; Male; Meclofenamic Acid; Muscle Contraction; Muscle, Smooth; Pyrilamine; SRS-A; Trachea

1994
Role of cysteinyl-leukotrienes and histamine in mediating intrinsic tone in isolated human bronchi.
    American journal of respiratory and critical care medicine, 1994, Volume: 149, Issue:1

    Topics: Bronchi; Chlorpheniramine; Dicarboxylic Acids; Female; Histamine; Humans; Hydroxyurea; In Vitro Techniques; Indazoles; Isometric Contraction; Isotonic Solutions; Leukotriene D4; Lipoxygenase Inhibitors; Male; Middle Aged; Muscle Tonus; Muscle, Smooth; Pyrilamine; SRS-A

1994
Effect of 5-lipoxygenase inhibitors on the anti-IgE-induced contraction of passively sensitized human bronchus in vitro.
    Journal of lipid mediators, 1993, Volume: 8, Issue:2

    Topics: Antibodies, Anti-Idiotypic; Bronchoconstriction; Humans; Hydroxyurea; Immunoglobulin E; In Vitro Techniques; Indoles; Leukotrienes; Lipoxygenase Inhibitors; Pyrilamine

1993
Selective effects of antileukotrienes on leukotriene and histamine release in human dispersed lung cells.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 1999, Volume: 48 Suppl 1

    Topics: Histamine H1 Antagonists; Histamine Release; Humans; Hydroxyurea; Indazoles; Leukotriene Antagonists; Leukotrienes; Lipoxygenase Inhibitors; Lung; Lung Neoplasms; Pyrilamine; Quinolines

1999
Concurrent blockade of platelet-activating factor and histamine prevents life-threatening peanut-induced anaphylactic reactions.
    The Journal of allergy and clinical immunology, 2009, Volume: 124, Issue:2

    Topics: Allergens; Anaphylaxis; Animals; Arachis; Cholera Toxin; Cimetidine; Disease Models, Animal; Drug Therapy, Combination; Enzyme Inhibitors; Female; Histamine; Histamine Antagonists; Histamine H1 Antagonists; Hydroxyurea; Immunoglobulin E; Immunoglobulin G; Lipoxygenase Inhibitors; Mice; Mice, Inbred C57BL; Peanut Hypersensitivity; Platelet Membrane Glycoproteins; Pyrilamine; Receptors, G-Protein-Coupled; Receptors, Histamine

2009