Page last updated: 2024-08-24

zileuton and phenyl acetate

zileuton has been researched along with phenyl acetate in 34 studies

Research

Studies (34)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (17.65)18.2507
2000's22 (64.71)29.6817
2010's5 (14.71)24.3611
2020's1 (2.94)2.80

Authors

AuthorsStudies
Tan, RA1
Lane, SJ1
Wedekind, CA1
Kuna, P; Kupczyk, M1
Dellaripa, PF; Drazen, J; Roth, ME; Wechsler, ME1
Bisgaard, H1
Krawiec, ME; Wenzel, SE1
García-Marcos, L; Schuster, A1
Spector, SL1
Adachi, M; Minoguchi, K1
Hayden, ML1
Capella, GL1
Valacer, DJ1
Jung, A1
Kemp, JP1
Blanc, PD; Eisner, MD; Katz, PP; Snyder, L; Yelin, EH1
Kulkarni, SK; Patil, CS; Singh, VP1
Dahlén, SE1
Ludington, E; Mehra, P; Simon, RA; Stevenson, DD; White, A1
Dickerson, KS; Luttermoser, GK; Scow, DT1
Bramanti, P; Caminiti, R; Cuzzocrea, S; Di Paola, R; Genovese, T; Mazzon, E; Muià, C; Rossi, A; Sautebin, L1
Bhattacharjee, R; Dayyat, E; Goldman, JL; Gozal, D; Kheirandish-Gozal, L; Serpero, LD; Snow, A1
Klanderman, B; Lima, J; Sylvia, J; Tantisira, KG; Weiss, ST1
Ayers, DC; Fanning, PJ; Gaur, T; Lian, JB; Mason-Savas, A; O'Connell, SL; Silva, J; Stein, GS; Wixted, JJ1
Bates, G; Di Capite, J; Nelson, C; Parekh, AB1
Gibbons, RD; Joo, MJ; Lee, TA; Schumock, GT; Stayner, LT; Valuck, RJ1
Kroegel, C1
Acikgoz, S; Baba, F; Banoglu, ZN; Dengiz, GO; Isikdemir, F; Kelek, S; Kurcer, Z; Sipahi, EY1
Dahlin, A; Irvin, CG; Kubo, M; Lima, JJ; Litonjua, A; Peters, SP; Tamari, M; Tantisira, KG1
Mosser-Goldfarb, JL; Yanes, DA1
Citron, F; Deem, AK; Genovese, G; Perelli, L; Viale, A1

Reviews

16 review(s) available for zileuton and phenyl acetate

ArticleYear
The role of antileukotrienes in asthma management.
    Current opinion in pulmonary medicine, 1998, Volume: 4, Issue:1

    Topics: Acetates; Animals; Anti-Asthmatic Agents; Asthma; Chromones; Cyclopropanes; Humans; Hydroxyurea; Indoles; Leukotriene Antagonists; Lipoxygenase Inhibitors; Phenylcarbamates; Quinolines; Sulfides; Sulfonamides; Tosyl Compounds

1998
Leukotriene antagonism in asthma and rhinitis.
    Respiratory medicine, 1998, Volume: 92, Issue:6

    Topics: Acetates; Asthma; Bronchi; Cyclopropanes; Humans; Hydroxyurea; Indoles; Leukotriene Antagonists; Leukotriene D4; Lipoxygenase Inhibitors; Membrane Proteins; Phenylcarbamates; Quinolines; Receptors, Leukotriene; Rhinitis; Sinusitis; Sulfides; Sulfonamides; Tosyl Compounds

1998
[The role of leukotrienes in inflammation and leukotriene inhibitors].
    Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 1999, Volume: 7, Issue:39

    Topics: Acetates; Arachidonate 5-Lipoxygenase; Asthma; Cyclopropanes; Humans; Hydroxyurea; Indoles; Leukotriene Antagonists; Leukotrienes; Phenylcarbamates; Quinolines; Sulfides; Sulfonamides; Tosyl Compounds

1999
Leukotriene modifiers in pediatric asthma management.
    Pediatrics, 2001, Volume: 107, Issue:2

    Topics: Acetates; Adrenal Cortex Hormones; Anti-Asthmatic Agents; Asthma; Child; Cyclopropanes; Humans; Hydroxyurea; Indoles; Leukotriene Antagonists; Leukotrienes; Membrane Proteins; Phenylcarbamates; Quinolines; Receptors, Leukotriene; Sulfides; Sulfonamides; Tosyl Compounds

2001
Leukotriene inhibitors and non-steroidal therapies in the treatment of asthma.
    Expert opinion on pharmacotherapy, 2001, Volume: 2, Issue:1

    Topics: Acetates; Adult; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Asthma; Bronchoconstriction; Child; Clinical Trials as Topic; Cyclopropanes; Humans; Hydroxyurea; Indoles; Leukotriene Antagonists; Phenylcarbamates; Phosphodiesterase Inhibitors; Quinolines; Sulfides; Sulfonamides; Tosyl Compounds; Treatment Outcome

2001
Antileukotrienes in asthma: present situation.
    Expert opinion on pharmacotherapy, 2001, Volume: 2, Issue:3

    Topics: Acetates; Anti-Asthmatic Agents; Asthma; Bronchodilator Agents; Chromones; Clinical Trials as Topic; Cyclopropanes; Humans; Hydroxyurea; Indoles; Leukotriene Antagonists; Leukotrienes; Phenylcarbamates; Quinolines; Sulfides; Sulfonamides; Tosyl Compounds

2001
[Leukotriene modifiers].
    Nihon rinsho. Japanese journal of clinical medicine, 2001, Volume: 59, Issue:10

    Topics: Acetates; Asthma; Chromones; Cyclopropanes; Humans; Hydroxyurea; Indoles; Leukotriene Antagonists; Leukotrienes; Lipoxygenase Inhibitors; Membrane Proteins; Phenylcarbamates; Practice Guidelines as Topic; Quinolines; Receptors, Leukotriene; Sulfides; Sulfonamides; Tosyl Compounds

2001
Leukotriene modifiers. Expanded role may be on horizon.
    Advance for nurse practitioners, 2000, Volume: 8, Issue:10

    Topics: Acetates; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Asthma; Cyclopropanes; Drug Interactions; Drug Therapy, Combination; Forced Expiratory Volume; Humans; Hydroxyurea; Indoles; Leukotriene Antagonists; Lipoxygenase Inhibitors; Patient Compliance; Phenylcarbamates; Quinolines; Safety; Steroids; Sulfides; Sulfonamides; Tosyl Compounds; Treatment Outcome

2000
New treatments for asthma: the role of leukotriene modifier agents.
    Journal of the National Medical Association, 1999, Volume: 91, Issue:8 Suppl

    Topics: Acetates; Anti-Asthmatic Agents; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Asthma, Exercise-Induced; Cyclopropanes; Drug Evaluation; Humans; Hydroxyurea; Indoles; Leukotriene Antagonists; Phenylcarbamates; Quinolines; Sulfides; Sulfonamides; Tosyl Compounds; Treatment Outcome

1999
[Anti-leukotrienes in allergic diseases in children].
    Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 2003, Volume: 14, Issue:84

    Topics: Acetates; Asthma; Child; Cyclopropanes; Humans; Hydroxyurea; Leukotriene Antagonists; Leukotrienes; Membrane Proteins; Quinolines; Receptors, Leukotriene; Sulfides

2003
Recent advances in the management of asthma using leukotriene modifiers.
    American journal of respiratory medicine : drugs, devices, and other interventions, 2003, Volume: 2, Issue:2

    Topics: Acetates; Administration, Inhalation; Adolescent; Adult; Asthma; Child; Child, Preschool; Chromones; Controlled Clinical Trials as Topic; Cyclopropanes; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hydroxyurea; Leukotriene Antagonists; Male; Middle Aged; Peak Expiratory Flow Rate; Quinolines; Respiratory Function Tests; Severity of Illness Index; Sulfides; Treatment Outcome

2003
Treatment of asthma with antileukotrienes: first line or last resort therapy?
    European journal of pharmacology, 2006, Mar-08, Volume: 533, Issue:1-3

    Topics: Acetates; Animals; Asthma; Clinical Trials as Topic; Cyclopropanes; Humans; Hydroxyurea; Leukotriene Antagonists; Leukotriene C4; Leukotriene D4; Leukotriene E4; Lipoxygenase Inhibitors; Membrane Proteins; Quinolines; Receptors, Leukotriene; Respiratory System; Rhinitis; Sulfides

2006
Leukotriene inhibitors in the treatment of allergy and asthma.
    American family physician, 2007, Jan-01, Volume: 75, Issue:1

    Topics: Acetates; Anti-Asthmatic Agents; Asthma; Asthma, Exercise-Induced; Cyclopropanes; Dermatitis, Atopic; Humans; Hydroxyurea; Hypersensitivity; Indoles; Leukotriene Antagonists; Phenylcarbamates; Quinolines; Rhinitis, Allergic, Perennial; Rhinitis, Allergic, Seasonal; Sulfides; Sulfonamides; Tosyl Compounds

2007
Association between leukotriene-modifying agents and suicide: what is the evidence?
    Drug safety, 2011, Jul-01, Volume: 34, Issue:7

    Topics: Acetates; Adverse Drug Reaction Reporting Systems; Cyclopropanes; Drug Labeling; Humans; Hydroxyurea; Indoles; Leukotriene Antagonists; Phenylcarbamates; Quinolines; Suicide; Sulfides; Sulfonamides; Tosyl Compounds; United States; United States Food and Drug Administration

2011
[What helps for persistent symptoms of asthma during inhalative steroid therapy?].
    Deutsche medizinische Wochenschrift (1946), 2011, Volume: 136, Issue:42

    Topics: Acetates; Administration, Inhalation; Adrenal Cortex Hormones; Adrenergic beta-2 Receptor Agonists; Adult; Albuterol; Anti-Asthmatic Agents; Asthma; Bronchodilator Agents; Child; Cyclopropanes; Drug Therapy, Combination; Ethanolamines; Formoterol Fumarate; Humans; Hydroxyurea; Leukotriene Antagonists; Quality of Life; Quinolines; Randomized Controlled Trials as Topic; Respiratory Function Tests; Salmeterol Xinafoate; Sulfides; Treatment Failure

2011
Emerging therapies for atopic dermatitis: The prostaglandin/leukotriene pathway.
    Journal of the American Academy of Dermatology, 2018, Volume: 78, Issue:3 Suppl 1

    Topics: Acetates; Adult; Animals; Cyclopropanes; Dermatitis, Atopic; Female; Forecasting; Humans; Hydroxyurea; Leukotriene Antagonists; Male; Molecular Targeted Therapy; Prostaglandin Antagonists; Quinolines; Severity of Illness Index; Sulfides; Treatment Outcome

2018

Trials

3 trial(s) available for zileuton and phenyl acetate

ArticleYear
Effect of leukotriene modifier drugs on the safety of oral aspirin challenges.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2006, Volume: 97, Issue:5

    Topics: Acetates; Adolescent; Adrenal Cortex Hormones; Adult; Aged; Anti-Asthmatic Agents; Aspirin; Asthma; Cyclopropanes; Desensitization, Immunologic; Drug Hypersensitivity; Female; Forced Expiratory Volume; Humans; Hydroxyurea; Indoles; Leukotriene Antagonists; Lipoxygenase Inhibitors; Male; Middle Aged; Phenylcarbamates; Quinolines; Sulfides; Sulfonamides; Tosyl Compounds; Treatment Outcome

2006
5-lipoxygenase pharmacogenetics in asthma: overlap with Cys-leukotriene receptor antagonist loci.
    Pharmacogenetics and genomics, 2009, Volume: 19, Issue:3

    Topics: Acetates; Adult; Anti-Asthmatic Agents; Asthma; Cyclopropanes; Cysteine; Female; Forced Expiratory Volume; Genotype; Humans; Hydroxyurea; Leukotriene Antagonists; Lipoxygenase Inhibitors; Male; Middle Aged; Polymorphism, Single Nucleotide; Quinolines; Receptors, Leukotriene; Sulfides

2009
Genome-wide association study of leukotriene modifier response in asthma.
    The pharmacogenomics journal, 2016, Volume: 16, Issue:2

    Topics: Acetates; Anti-Asthmatic Agents; Asthma; Cohort Studies; Cyclopropanes; Gene-Environment Interaction; Genetic Loci; Genome-Wide Association Study; Genotype; Humans; Hydroxyurea; Leukotrienes; Phenotype; Polymorphism, Single Nucleotide; Quinolines; Sulfides

2016

Other Studies

15 other study(ies) available for zileuton and phenyl acetate

ArticleYear
Drugs for asthma.
    The Medical letter on drugs and therapeutics, 1999, Jan-15, Volume: 41, Issue:1044

    Topics: Acetates; Administration, Inhalation; Administration, Oral; Adolescent; Adrenal Cortex Hormones; Adrenergic beta-Agonists; Adult; Aged; Albuterol; Asthma; Bone Density; Bronchial Spasm; Bronchodilator Agents; Child; Child, Preschool; Choice Behavior; Cromolyn Sodium; Cyclopropanes; Exercise; Female; Growth; Humans; Hydroxyurea; Indoles; Infant, Newborn; Ipratropium; Lactation; Leukotriene Antagonists; Phenylcarbamates; Pregnancy; Pregnancy Complications; Quinolines; Salmeterol Xinafoate; Sulfides; Sulfonamides; Tachycardia; Theophylline; Tosyl Compounds

1999
Leukotriene modifiers--a new treatment option for asthma.
    Medicine and health, Rhode Island, 1999, Volume: 82, Issue:7

    Topics: Acetates; Anti-Asthmatic Agents; Cyclopropanes; Humans; Hydroxyurea; Indoles; Leukotriene Antagonists; Phenylcarbamates; Quinolines; Sulfides; Sulfonamides; Tosyl Compounds; Treatment Outcome

1999
Drugs for asthma.
    The Medical letter on drugs and therapeutics, 2000, Mar-06, Volume: 42, Issue:1073

    Topics: Acetates; Administration, Inhalation; Administration, Oral; Adrenal Cortex Hormones; Adrenergic beta-2 Receptor Agonists; Adrenergic beta-Agonists; Adult; Albuterol; Asthma; Bronchial Spasm; Child; Cromolyn Sodium; Cyclopropanes; Exercise; Female; Growth Disorders; Humans; Hydroxyurea; Indoles; Ipratropium; Lactation; Leukotriene Antagonists; Nebulizers and Vaporizers; Nedocromil; Phenylcarbamates; Pregnancy; Pregnancy Complications; Quinolines; Salmeterol Xinafoate; Sulfides; Sulfonamides; Theophylline; Tosyl Compounds

2000
The use of newer asthma and allergy medications during pregnancy. The American College of Obstetricians and Gynecologists (ACOG) and The American College of Allergy, Asthma and Immunology (ACAAI).
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2000, Volume: 84, Issue:5

    Topics: Abnormalities, Drug-Induced; Acetates; Administration, Inhalation; Administration, Intranasal; Administration, Oral; Adrenal Cortex Hormones; Adrenergic beta-Agonists; Albuterol; Animals; Anti-Allergic Agents; Anti-Asthmatic Agents; Asthma; Budesonide; Chlorpheniramine; Cyclopropanes; Ephedrine; Female; Histamine H1 Antagonists; Humans; Hydroxyurea; Hypersensitivity; Indoles; Ipratropium; Leukotriene Antagonists; Metaproterenol; Nasal Decongestants; Nebulizers and Vaporizers; Nedocromil; Phenylcarbamates; Pregnancy; Pregnancy Complications; Quinolines; Salmeterol Xinafoate; Sulfides; Sulfonamides; Terbutaline; Tosyl Compounds; Tripelennamine

2000
Recurrent panniculitis in a man with asthma receiving treatment with leukotriene-modifying agents.
    Mayo Clinic proceedings, 2000, Volume: 75, Issue:6

    Topics: Acetates; Anti-Asthmatic Agents; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Cyclopropanes; Diagnosis, Differential; Erythema Induratum; Humans; Hydroxyurea; Leukotriene Antagonists; Lipoxygenase Inhibitors; Male; Middle Aged; Panniculitis, Nodular Nonsuppurative; Quinolines; Sulfides

2000
Safety of antileukotriene agents in asthma management.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2001, Volume: 86, Issue:6 Suppl 1

    Topics: Acetates; Asthma; Churg-Strauss Syndrome; Clinical Trials as Topic; Cyclopropanes; Humans; Hydroxyurea; Indoles; Leukotriene Antagonists; Phenylcarbamates; Quinolines; Sulfides; Sulfonamides; Tosyl Compounds

2001
Anti-leukotriene drugs in the prevention and treatment of hepatorenal syndrome.
    Prostaglandins, leukotrienes, and essential fatty acids, 2003, Volume: 68, Issue:4

    Topics: Acetates; Arachidonic Acid; Cyclopropanes; Hepatorenal Syndrome; Humans; Hydroxyurea; Indoles; Leukotriene Antagonists; Leukotrienes; Liver; Phenylcarbamates; Protein Structure, Tertiary; Quinolines; Sulfides; Sulfonamides; Thromboxanes; Tosyl Compounds

2003
Leukotriene modifier use and asthma severity: how is a new medication being used by adults with asthma?
    Archives of internal medicine, 2004, Mar-22, Volume: 164, Issue:6

    Topics: Acetates; Adult; Anti-Asthmatic Agents; Asthma; Cyclopropanes; Female; Health Status Indicators; Hospitalization; Humans; Hydroxyurea; Leukotriene Antagonists; Logistic Models; Longitudinal Studies; Male; Middle Aged; Prospective Studies; Quinolines; Sulfides

2004
Differential effect of zileuton, a 5-lipoxygenase inhibitor, against nociceptive paradigms in mice and rats.
    Pharmacology, biochemistry, and behavior, 2005, Volume: 81, Issue:3

    Topics: Acetates; Acetic Acid; Analgesics; Animals; Capillary Permeability; Carrageenan; Cyclopropanes; Dose-Response Relationship, Drug; Female; Hindlimb; Hydroxyurea; Hyperalgesia; Indoles; Inflammation; Leukotriene Antagonists; Lipoxygenase Inhibitors; Male; Mice; Pain; Pain Measurement; Phenylcarbamates; Quinolines; Rats; Rats, Wistar; Receptors, Leukotriene B4; Sulfides; Sulfonamides; Tosyl Compounds

2005
Effects of zileuton and montelukast in mouse experimental spinal cord injury.
    British journal of pharmacology, 2008, Volume: 153, Issue:3

    Topics: Acetates; Animals; Apoptosis; Arachidonate 5-Lipoxygenase; Cyclooxygenase 2; Cyclopropanes; Cysteine; Dinoprostone; Disease Models, Animal; Gene Expression Regulation; Hydroxyurea; Inflammation; Leukotrienes; Lipoxygenase Inhibitors; Male; Mice; Neutrophil Infiltration; Quinolines; Recovery of Function; Spinal Cord Injuries; Sulfides; Tumor Necrosis Factor-alpha

2008
Leukotriene pathways and in vitro adenotonsillar cell proliferation in children with obstructive sleep apnea.
    Chest, 2009, Volume: 135, Issue:5

    Topics: Acetates; Adenoids; Apoptosis; Cell Proliferation; Cells, Cultured; Child; Child, Preschool; Cyclopropanes; Dose-Response Relationship, Drug; Humans; Hydroxyurea; Immunohistochemistry; Interleukins; Leukotriene Antagonists; Leukotriene D4; Palatine Tonsil; Polysomnography; Quinolines; Sleep Apnea, Obstructive; SRS-A; Sulfides

2009
Enhanced fracture repair by leukotriene antagonism is characterized by increased chondrocyte proliferation and early bone formation: a novel role of the cysteinyl LT-1 receptor.
    Journal of cellular physiology, 2009, Volume: 221, Issue:1

    Topics: Acetates; Animals; Arachidonate 5-Lipoxygenase; Cell Proliferation; Chondrocytes; Cyclopropanes; Fracture Healing; Fractures, Bone; Gene Expression Regulation; Hydroxyurea; Hypertrophy; Leukotriene Antagonists; Leukotriene B4; Mice; Models, Biological; Osteogenesis; Quinolines; Radiography; Receptors, Leukotriene; Sulfides

2009
Targeting Ca2+ release-activated Ca2+ channel channels and leukotriene receptors provides a novel combination strategy for treating nasal polyposis.
    The Journal of allergy and clinical immunology, 2009, Volume: 124, Issue:5

    Topics: Acetates; Arachidonate 5-Lipoxygenase; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium Signaling; Cyclopropanes; Humans; Hydroxyurea; Leukotriene Antagonists; Leukotriene C4; Mast Cells; Nasal Polyps; Quinolines; Receptors, Leukotriene; Sulfides; Thapsigargin

2009
Effects of montelukast and zileuton on testicular torsion/detorsion injury in rats.
    Andrologia, 2014, Volume: 46, Issue:1

    Topics: Acetates; Animals; Cyclopropanes; Hydroxyurea; Male; Malondialdehyde; Quinolines; Rats; Rats, Wistar; Spermatic Cord Torsion; Sulfides

2014
Leukotrienes, a potential target for Covid-19.
    Prostaglandins, leukotrienes, and essential fatty acids, 2020, Volume: 161

    Topics: Acetates; Adrenal Cortex Hormones; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Betacoronavirus; Coronavirus Infections; COVID-19; Cyclopropanes; Cytokine Release Syndrome; Humans; Hydroxyurea; Immunologic Factors; Indoles; Leukotrienes; Pandemics; Phenylcarbamates; Pneumonia, Viral; Quinolines; SARS-CoV-2; Severity of Illness Index; Sulfides; Sulfonamides; Tosyl Compounds

2020