Page last updated: 2024-08-24

zileuton and ml-3000

zileuton has been researched along with ml-3000 in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's6 (75.00)24.3611
2020's2 (25.00)2.80

Authors

AuthorsStudies
Aparoy, P; Chandramohan Reddy, T; Kalangi, SK; Kumar Reddy, K; Reddanna, P1
Gao, Y; He, C; He, S; Lai, L; Liu, Y; Wu, Y1
Davis, MI; Khan, J; Li, SQ; Patel, PR; Shen, M; Sun, H; Thomas, CJ1
Aidhen, IS; Doble, M; Ramanan, M; Sinha, S; Sudarshan, K1
Bandresh, R; Shrivastava, SK; Srivastava, P; Tripathi, A; Tripathi, PN1
Codd, R; Gotsbacher, MP; Roth, L1
Bhatti, R; Kaur, J; Kumari, P; Singh, P1
Dehm, F; Gerstmeier, J; Koeberle, A; Laufer, S; Maier, TJ; Northoff, H; Pace, S; Pein, H; Pergola, C; Rådmark, O; Rossi, A; Rummler, S; Samuelsson, B; Sautebin, L; Schaible, AM; Troisi, F; Weinigel, C; Werz, O1

Other Studies

8 other study(ies) available for zileuton and ml-3000

ArticleYear
Pharmacophore modeling and virtual screening for designing potential 5-lipoxygenase inhibitors.
    Bioorganic & medicinal chemistry letters, 2010, Feb-01, Volume: 20, Issue:3

    Topics: Arachidonate 5-Lipoxygenase; Computer Simulation; Drug Design; Drug Evaluation, Preclinical; Lipoxygenase Inhibitors; Models, Chemical; Models, Molecular

2010
Dynamic modeling of human 5-lipoxygenase-inhibitor interactions helps to discover novel inhibitors.
    Journal of medicinal chemistry, 2012, Mar-22, Volume: 55, Issue:6

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Arachidonate 5-Lipoxygenase; Cell-Free System; Databases, Factual; Dinoprostone; Humans; Intramolecular Oxidoreductases; Leukotriene B4; Lipoxygenase Inhibitors; Microsomes; Molecular Dynamics Simulation; Prostaglandin-E Synthases; Protein Binding; Protein Conformation; Pyrroles; Recombinant Proteins; Structure-Activity Relationship

2012
Identification of potent Yes1 kinase inhibitors using a library screening approach.
    Bioorganic & medicinal chemistry letters, 2013, Aug-01, Volume: 23, Issue:15

    Topics: Binding Sites; Cell Line; Cell Survival; Drug Design; Humans; Hydrogen Bonding; Molecular Docking Simulation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-yes; Small Molecule Libraries; Structure-Activity Relationship

2013
Inhibition of the enzymes in the leukotriene and prostaglandin pathways in inflammation by 3-aryl isocoumarins.
    European journal of medicinal chemistry, 2016, Nov-29, Volume: 124

    Topics: Arachidonate 5-Lipoxygenase; Arachidonic Acid; Cytokines; Dinoprostone; Free Radicals; Gene Expression Regulation, Enzymologic; HeLa Cells; Humans; Inflammation; Isocoumarins; Kinetics; Leukotrienes; Lipoxygenase Inhibitors; Prostaglandins; RNA, Messenger

2016
Design, synthesis, and biological evaluation of some novel indolizine derivatives as dual cyclooxygenase and lipoxygenase inhibitor for anti-inflammatory activity.
    Bioorganic & medicinal chemistry, 2017, 08-15, Volume: 25, Issue:16

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Carrageenan; Cyclooxygenase Inhibitors; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Design; Edema; Female; Indolizines; Lipoxygenase; Lipoxygenase Inhibitors; Male; Mice; Molecular Structure; Prostaglandin-Endoperoxide Synthases; Rats; Structure-Activity Relationship; Ulcer

2017
Immobilized Metal Affinity Chromatography as a Drug Discovery Platform for Metalloenzyme Inhibitors.
    Journal of medicinal chemistry, 2020, 10-22, Volume: 63, Issue:20

    Topics: Chromatography, Affinity; Coordination Complexes; Crystallography, X-Ray; Dose-Response Relationship, Drug; Drug Discovery; Humans; Imino Acids; Metalloproteins; Metals, Heavy; Models, Molecular; Molecular Structure; Structure-Activity Relationship

2020
Design, Synthesis, and Activity Evaluation of Stereoconfigured Tartarate Derivatives as Potential Anti-inflammatory Agents
    Journal of medicinal chemistry, 2021, 07-08, Volume: 64, Issue:13

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dose-Response Relationship, Drug; Drug Design; Edema; Female; Humans; Lipoxygenase; Lipoxygenase Inhibitors; Male; Mice; Molecular Structure; Stereoisomerism; Structure-Activity Relationship; Tartrates

2021
Androgen-mediated sex bias impairs efficiency of leukotriene biosynthesis inhibitors in males.
    The Journal of clinical investigation, 2017, Aug-01, Volume: 127, Issue:8

    Topics: 5-Lipoxygenase-Activating Proteins; Androgens; Animals; Arachidonate 5-Lipoxygenase; Dihydrotestosterone; Female; Humans; Hydroxyurea; Leukocytes; Leukotrienes; Lipoxygenase Inhibitors; Male; Mice; Pyrroles; Rats; Rats, Wistar; Sex Factors; Sulindac; Testosterone

2017
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