zileuton has been researched along with masoprocol in 16 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (37.50) | 18.2507 |
| 2000's | 2 (12.50) | 29.6817 |
| 2010's | 7 (43.75) | 24.3611 |
| 2020's | 1 (6.25) | 2.80 |
| Authors | Studies |
|---|---|
| Bélanger, PC; Denis, D; Dufresne, C; Fitzsimmons, B; Ford-Hutchinson, AW; Lau, CK; Riendeau, D; Scheigetz, J; Therien, M; Young, RN | 1 |
| Kreft, AF; Musser, JH | 1 |
| Bell, RL; Brooks, DW; Carter, GW; Dyer, RD; Holms, JH; Kerdesky, FA; Moore, JL | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Hashimoto, K; Hasumi, K; Koshino, H; Takahashi, S; Tani, H; Tatefuji, T | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Holman, TR; Holz, C; Hoobler, EK | 1 |
| Achenbach, J; Barzen, S; Brüggerhoff, A; Hofmann, B; Ihlefeld, K; Kretschmer, SB; Proschak, E; Rödl, CB; Stark, H; Steinhilber, D; Vogt, D | 1 |
| de Andrés, L; Estrada Valencia, M; Herrera-Arozamena, C; Laurini, E; Morales-García, JA; Pérez, C; Pérez-Castillo, A; Pricl, S; Ramos, E; Rodríguez-Franco, MI; Romero, A; Viña, D; Yáñez, M | 1 |
| Abu-Serie, MM; AlFadly, ED; Bakkar, NZ; Bartolini, M; Belal, ASF; El-Yazbi, AF; Elkazaz, S; Elzahhar, PA; Ghareeb, DA; Iriepa, I; Janockova, J; Kobeissy, F; Moraleda, I; Rafeh, RW; Saudi, MNS; Shaltout, H; Soukup, O; Tramarin, A | 1 |
| Fukushima, EO; Muranaka, T; Nomura, Y; Vo, NNQ | 1 |
| Cuadrado, A; Duarte, P; Estrada-Valencia, M; Fernández-Ginés, R; Franco-Gonzalez, JF; Gago, F; García-Yagüe, ÁJ; Herrera-Arozamena, C; Lagartera, L; León, R; López, MG; Michalska, P; Mills, A; Morales-García, JA; Pérez, C; Pérez-Castillo, A; Rodríguez-Franco, MI | 1 |
| Grisham, MB; Keenan, CM; Vaananen, PM; Wallace, JL | 1 |
| Kasiske, BL; Keane, WF; Kim, Y; O'Donnell, MP | 1 |
| Hardy, DB; Pereria, LE; Yang, K | 1 |
| Donoghue, DJ; McAndrew, CW; Meyer, AN | 1 |
1 review(s) available for zileuton and masoprocol
| Article | Year |
|---|---|
5-lipoxygenase: properties, pharmacology, and the quinolinyl(bridged)aryl class of inhibitors.
Topics: Animals; Arachidonate 5-Lipoxygenase; Asthma; Eosinophils; Humans; Inflammation; Leukotriene Antagonists; Lipoxygenase Inhibitors; Lung Diseases; Neutrophils; Quinolines | 1992 |
15 other study(ies) available for zileuton and masoprocol
| Article | Year |
|---|---|
Development of 2,3-dihydro-6-(3-phenoxypropyl)-2-(2-phenylethyl)-5-benzofuranol (L-670,630) as a potent and orally active inhibitor of 5-lipoxygenase.
Topics: Animals; Arachidonate 5-Lipoxygenase; Benzofurans; Biological Availability; Bronchoconstriction; Dogs; Humans; Leukocytes, Mononuclear; Leukotriene B4; Lipoxygenase Inhibitors; Male; Methemoglobin; Microsomes, Liver; Molecular Structure; Rats; Rats, Inbred Strains; Saimiri; Structure-Activity Relationship | 1992 |
4-hydroxythiazole inhibitors of 5-lipoxygenase.
Topics: Animals; Arachidonate 5-Lipoxygenase; Chemical Phenomena; Chemistry; Enzyme Inhibitors; Humans; Lipoxygenase Inhibitors; Male; Rats; Rats, Inbred Strains; Structure-Activity Relationship; Thiazoles | 1991 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Inhibitory activity of Brazilian green propolis components and their derivatives on the release of cys-leukotrienes.
Topics: Animals; Anti-Allergic Agents; Bees; Cell Line, Tumor; Cysteine; Histamine; Humans; Leukocytes; Leukotrienes; Propolis; Rhinitis, Allergic, Seasonal | 2010 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Pseudoperoxidase investigations of hydroperoxides and inhibitors with human lipoxygenases.
Topics: Enzyme Assays; Humans; Hydrogen Peroxide; Linoleic Acids; Lipid Peroxides; Lipoxygenase Inhibitors; Lipoxygenases; Oxidation-Reduction; Peroxidase; Phenols; Sulfoxides | 2013 |
Multi-dimensional target profiling of N,4-diaryl-1,3-thiazole-2-amines as potent inhibitors of eicosanoid metabolism.
Topics: 5-Lipoxygenase-Activating Proteins; Aminophenols; Cyclooxygenase 2; Dose-Response Relationship, Drug; Eicosanoids; Enzyme Inhibitors; HeLa Cells; Humans; Molecular Structure; Structure-Activity Relationship; Thiazoles; Tumor Cells, Cultured; U937 Cells | 2014 |
Neurogenic and neuroprotective donepezil-flavonoid hybrids with sigma-1 affinity and inhibition of key enzymes in Alzheimer's disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Cell Line; Cholinesterase Inhibitors; Donepezil; Enzyme Inhibitors; Flavonoids; Humans; Indans; Lipoxygenase Inhibitors; Male; Mice, Inbred BALB C; Models, Molecular; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Neurogenesis; Neuroprotective Agents; Piperidines; Receptors, sigma; Sigma-1 Receptor | 2018 |
Tackling neuroinflammation and cholinergic deficit in Alzheimer's disease: Multi-target inhibitors of cholinesterases, cyclooxygenase-2 and 15-lipoxygenase.
Topics: Acetylcholine; Alzheimer Disease; Animals; Cell Line; Cholinesterase Inhibitors; Cyclooxygenase 2 Inhibitors; Drug Design; Humans; Inflammation; Lipoxygenase Inhibitors; Mice; Molecular Docking Simulation; Neurons; PC12 Cells; Rats; Semicarbazides; Triazoles | 2019 |
Structure-Activity Relationships of Pentacyclic Triterpenoids as Inhibitors of Cyclooxygenase and Lipoxygenase Enzymes.
Topics: Cyclooxygenase Inhibitors; Drug Evaluation, Preclinical; Humans; Lipoxygenase Inhibitors; Pentacyclic Triterpenes; Structure-Activity Relationship | 2019 |
Tuning melatonin receptor subtype selectivity in oxadiazolone-based analogues: Discovery of QR2 ligands and NRF2 activators with neurogenic properties.
Topics: Animals; Antioxidants; Cell Line, Tumor; CHO Cells; Cricetulus; Humans; Indoles; Kelch-Like ECH-Associated Protein 1; Ligands; Lipoxygenase Inhibitors; Molecular Conformation; Molecular Docking Simulation; Molecular Dynamics Simulation; Monoamine Oxidase Inhibitors; Naphthalenes; Neurogenesis; NF-E2-Related Factor 2; Oxadiazoles; Protein Binding; Quinone Reductases; Receptor, Melatonin, MT1; Receptor, Melatonin, MT2 | 2020 |
Pharmacological investigation of the role of leukotrienes in the pathogenesis of experimental NSAID gastropathy.
Topics: 5-Lipoxygenase-Activating Proteins; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Benzopyrans; Carrier Proteins; Free Radical Scavengers; Gastric Mucosa; Hydroxyurea; Indoles; Indomethacin; Leukotriene Antagonists; Leukotriene B4; Leukotrienes; Lipoxygenase Inhibitors; Male; Masoprocol; Membrane Proteins; Organic Chemicals; Permeability; Phenylcarbamates; Propionates; Quinolines; Rats; Rats, Inbred Strains; Receptors, Immunologic; Receptors, Leukotriene; Receptors, Leukotriene B4; Single-Blind Method; Stomach Ulcer; Sulfonamides; Tetrazoles; Tosyl Compounds | 1992 |
Oxidative modification of low-density lipoproteins by mesangial cells.
Topics: Antioxidants; Arachidonic Acid; Butylated Hydroxytoluene; Catalase; Cell Division; Cells, Cultured; Cyclooxygenase Inhibitors; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Deferoxamine; DNA Replication; Glomerular Mesangium; Glomerulosclerosis, Focal Segmental; Humans; Hydroxyurea; Indomethacin; Ketoconazole; Lipoproteins, LDL; Lipoxygenase Inhibitors; Masoprocol; Oxidation-Reduction; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances | 1993 |
Prostaglandins and leukotriene B4 are potent inhibitors of 11beta-hydroxysteroid dehydrogenase type 2 activity in human choriocarcinoma JEG-3 cells.
Topics: 11-beta-Hydroxysteroid Dehydrogenases; Choriocarcinoma; Dinoprost; Dinoprostone; Enzyme Inhibitors; Humans; Hydroxysteroid Dehydrogenases; Hydroxyurea; Indomethacin; Isoenzymes; Leukotriene B4; Lipoxygenase Inhibitors; Masoprocol; Placenta; Prostaglandins; Tumor Cells, Cultured | 1999 |
Nordihydroguaiaretic acid inhibits an activated fibroblast growth factor receptor 3 mutant and blocks downstream signaling in multiple myeloma cells.
Topics: Apoptosis; Cell Line, Tumor; Fibroblast Growth Factor 2; Golgi Apparatus; Humans; Hydroxyurea; Lipoxygenase Inhibitors; Masoprocol; Multiple Myeloma; Phosphorylation; Receptor, Fibroblast Growth Factor, Type 3; Signal Transduction; Thanatophoric Dysplasia; Transfection | 2008 |