zileuton has been researched along with ici d2138 in 11 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 8 (72.73) | 18.2507 |
| 2000's | 1 (9.09) | 29.6817 |
| 2010's | 2 (18.18) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bird, TG; Bruneau, P; Crawley, GC; Dowell, RI; Edwards, PN; Foster, SJ; Giroaeau, JM; McMillan, RM; Walker, ER; Waterson, D | 1 |
| Brooks, CD; Summers, JB | 1 |
| Brideau, C; Chan, CC; Chauret, N; Delorme, D; Desmarais, S; Dubé, D; Ducharme, Y; Falgueyret, JP; Fortin, R; Girard, Y; Guay, J; Hamel, P; Jones, TR; Lépine, C; Li, C; McAuliffe, M; McFarlane, CS; Nicoll-Griffith, DA; Riendeau, D; Yergey, JA | 1 |
| Aparoy, P; Chandramohan Reddy, T; Kalangi, SK; Kumar Reddy, K; Reddanna, P | 1 |
| Bridoux, A; Henichart, JP; Millet, R; Pommery, J; Pommery, N | 1 |
| Crawley, GC; Foster, SJ; McMillan, RM; Spruce, KE; Walker, ER | 1 |
| Carpenter, TG; Cuthbert, NJ; Fitzgerald, MF; Francis, HP; Gardiner, PJ; Mohrs, K; Müller-Peddinghaus, R; Newton, BB; Patel, UP; Thompson, AM | 1 |
| Currie, JL; Isakson, PC; Rao, TS; Shaffer, AF | 1 |
| Currie, JL; Isakson, PC; Kim, S; Rao, T; Shaffer, AF; Smith, WG; Thompson, JM | 1 |
| Andresen, CJ; Eggler, JF; Smith, WB; Turner, CR; Watson, JW | 1 |
| Amacher, DE; Beierschmitt, WP; Griffiths, RJ; McNeish, JD; Nagahisa, A; Nakane, M | 1 |
1 review(s) available for zileuton and ici d2138
| Article | Year |
|---|---|
Modulators of leukotriene biosynthesis and receptor activation.
Topics: 5-Lipoxygenase-Activating Proteins; Animals; Carrier Proteins; Forecasting; Humans; Leukotriene B4; Leukotrienes; Lipoxygenase Inhibitors; Membrane Proteins; Molecular Structure; Receptors, Leukotriene | 1996 |
10 other study(ies) available for zileuton and ici d2138
| Article | Year |
|---|---|
Methoxytetrahydropyrans. A new series of selective and orally potent 5-lipoxygenase inhibitors.
Topics: Administration, Oral; Animals; Calcimycin; Drug Interactions; Eicosanoids; Humans; Leukotriene B4; Lipoxygenase Inhibitors; Macrophages; Mice; Naphthalenes; Peritoneal Cavity; Pyrans; Quinolones; Rats; Structure-Activity Relationship; Thiazoles | 1992 |
Dioxabicyclooctanyl naphthalenenitriles as nonredox 5-lipoxygenase inhibitors: structure-activity relationship study directed toward the improvement of metabolic stability.
Topics: Animals; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Benzofurans; Bronchoconstriction; Drug Stability; Humans; Leukotriene B4; Leukotrienes; Lipoxygenase Inhibitors; Male; Microsomes, Liver; Molecular Structure; Naphthalenes; Neutrophils; Nitriles; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Saimiri; Structure-Activity Relationship | 1996 |
Pharmacophore modeling and virtual screening for designing potential 5-lipoxygenase inhibitors.
Topics: Arachidonate 5-Lipoxygenase; Computer Simulation; Drug Design; Drug Evaluation, Preclinical; Lipoxygenase Inhibitors; Models, Chemical; Models, Molecular | 2010 |
Synthesis and biological activity of N-aroyl-tetrahydro-gamma-carbolines.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Carbolines; Cell Line, Tumor; Cell Proliferation; Cyclooxygenase Inhibitors; Humans; Indomethacin; Lipoxygenase Inhibitors; Male; Prostatic Neoplasms; Structure-Activity Relationship | 2010 |
Pre-clinical pharmacology of ICI D2138, a potent orally-active non-redox inhibitor of 5-lipoxygenase.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Bronchoconstriction; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Guinea Pigs; Hydroxyurea; Inflammation; Knee Joint; Leukotriene B4; Lipoxygenase Inhibitors; Macrophages; Male; Mice; Oxidation-Reduction; Pyrans; Quinolones; Rabbits; Rats; Thromboxane B2 | 1992 |
Inhibition of antigen-induced contraction of guinea-pig airways by a leukotriene synthesis inhibitor, BAY x1005.
Topics: 5-Lipoxygenase-Activating Proteins; Administration, Oral; Animals; Benzoquinones; Bronchoconstriction; Carrier Proteins; Guinea Pigs; Hydroxyurea; In Vitro Techniques; Indoles; Injections, Intravenous; Leukotriene Antagonists; Lipoxygenase Inhibitors; Male; Membrane Proteins; Ovalbumin; Pyrans; Quinolines; Quinolones; Trachea | 1994 |
Evaluation of 5-lipoxygenase inhibitors, zileuton, A-78773 and ICI-D-2138 in an ionophore (A-23187)-induced pleural inflammation model in the rat.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Calcimycin; Disease Models, Animal; Drug Evaluation, Preclinical; Eicosanoids; Hydroxyurea; Leukotrienes; Lipoxygenase Inhibitors; Male; Pleurisy; Prostaglandins; Pyrans; Quinolones; Rats; Rats, Sprague-Dawley | 1993 |
Characterization of 5-lipoxygenase inhibitors in biochemical and functional in vivo assays.
Topics: Animals; Antigens; Blood Vessels; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Calcimycin; Guinea Pigs; Humans; Hydroxyurea; Indomethacin; Lipoxygenase Inhibitors; Male; Pyrans; Quinolones; Rats; Skin | 1995 |
The effect of 5-lipoxygenase inhibition on Ascaris antigen (Ag)-induced responses in atopic monkeys.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antigens, Helminth; Ascaris suum; Bronchoalveolar Lavage Fluid; Hydroxyurea; Inflammation; Leukocyte Count; Lipoxygenase Inhibitors; Macaca fascicularis; Male; Neutrophils; Pyrans; Quinolones | 1996 |
Induction of hepatic microsomal drug-metabolizing enzymes by inhibitors of 5-lipoxygenase (5-LO): studies in rats and 5-LO knockout mice.
Topics: Animals; Arachidonate 5-Lipoxygenase; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Enzyme Induction; Hydroxyurea; Lipoxygenase Inhibitors; Liver; Male; Mice; Mice, Inbred DBA; Mice, Knockout; Microsomes, Liver; NADH Dehydrogenase; Organ Size; Pyrans; Quinolones; Rats; Rats, Sprague-Dawley | 2001 |