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zileuton and a 78773

zileuton has been researched along with a 78773 in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's8 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Basha, A; Bhatia, P; Bouska, JB; Brooks, CD; Craig, RA; Kolasa, T; Lanni, C; Martin, JG; Ratajczyk, JD; Stewart, AO1
Bell, RL; Bhatia, PA; Bouska, JB; Brooks, CD; Carter, GW; Craig, RA; DeNinno, SL; Holms, JH; Kerdesky, FA; Kolasa, T; Lanni, C; Maki, RG; Martin, JG; Martin, MB; Mazdiyasni, H; Moore, JL; Ratajczyk, JD; Rodriques, KE; Stewart, AO; Summers, JB; Young, PR1
Cai, X; Eckman, J; Hussoin, MS; Hwang, SB; Ip, SH; Killian, DB; Libertine-Garahan, L; Qian, C; Scannell, RT; Shen, TY; Yaeger, D; Yeh, CG1
Bell, RL; Bouska, JB; Brooks, DW; Carter, GW; Harris, RR; Lanni, C; Malo, PE; Otis, ER; Stewart, AO1
Bell, RL; Brooks, DW; Carter, GW; Hansen, R; Lanni, C; Malo, PE; Rubin, P; Stewart, AO1
Currie, JL; Isakson, PC; Rao, TS; Shaffer, AF1
Currie, JL; Isakson, PC; Kim, S; Rao, T; Shaffer, AF; Smith, WG; Thompson, JM1
Kearney, AS; McLoughlin, M; Palepu, NR1

Other Studies

8 other study(ies) available for zileuton and a 78773

ArticleYear
(R)-(+)-N-[3-[5-[(4-fluorophenyl)methyl]-2-thienyl]-1-methyl- 2-propynyl]-N-hydroxyurea (ABT-761), a second-generation 5-lipoxygenase inhibitor.
    Journal of medicinal chemistry, 1995, Nov-24, Volume: 38, Issue:24

    Topics: Animals; Humans; Hydroxyurea; Lipoxygenase Inhibitors; Macaca fascicularis; Male; Microsomes, Liver; Rats; Rats, Sprague-Dawley; Stereoisomerism; Structure-Activity Relationship

1995
Structure-activity relationships of N-hydroxyurea 5-lipoxygenase inhibitors.
    Journal of medicinal chemistry, 1997, Jun-20, Volume: 40, Issue:13

    Topics: Animals; Cells, Cultured; Drug Design; Enzyme Inhibitors; Furans; Glucuronates; Humans; Hydroxyurea; Lipoxygenase Inhibitors; Macaca fascicularis; Models, Chemical; Rats; Structure-Activity Relationship; Templates, Genetic; Thiophenes

1997
(+/-)-trans-2-[3-methoxy-4-(4-chlorophenylthioethoxy)-5-(N-methyl-N- hydroxyureidyl)methylphenyl]-5-(3,4, 5-trimethoxyphenyl)tetrahydrofuran (CMI-392), a potent dual 5-lipoxygenase inhibitor and platelet-activating factor receptor antagonist.
    Journal of medicinal chemistry, 1998, May-21, Volume: 41, Issue:11

    Topics: Animals; Arachidonic Acid; Blood Platelets; Cell Membrane; CHO Cells; Cricetinae; Drug Evaluation, Preclinical; Edema; Enzyme Inhibitors; Furans; Hematocrit; Humans; Leukotriene B4; Lipoxygenase Inhibitors; Mice; Platelet Membrane Glycoproteins; Rats; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Urea

1998
Optimization of the potency and duration of action of N-hydroxyurea 5-lipoxygenase inhibitors.
    The Journal of pharmacology and experimental therapeutics, 1995, Volume: 272, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Haplorhini; Humans; Hydroxyurea; Leukotriene B4; Lipoxygenase Inhibitors; Mice; Rats; Stereoisomerism

1995
Preclinical and clinical activity of zileuton and A-78773.
    Annals of the New York Academy of Sciences, 1993, Nov-30, Volume: 696

    Topics: Animals; Bronchial Spasm; Guinea Pigs; Hydroxyurea; Inflammation; Leukotriene B4; Lipoxygenase Inhibitors; Lung; Male; Rats

1993
Evaluation of 5-lipoxygenase inhibitors, zileuton, A-78773 and ICI-D-2138 in an ionophore (A-23187)-induced pleural inflammation model in the rat.
    Life sciences, 1993, Volume: 53, Issue:9

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Calcimycin; Disease Models, Animal; Drug Evaluation, Preclinical; Eicosanoids; Hydroxyurea; Leukotrienes; Lipoxygenase Inhibitors; Male; Pleurisy; Prostaglandins; Pyrans; Quinolones; Rats; Rats, Sprague-Dawley

1993
Characterization of 5-lipoxygenase inhibitors in biochemical and functional in vivo assays.
    The Journal of pharmacology and experimental therapeutics, 1995, Volume: 275, Issue:3

    Topics: Animals; Antigens; Blood Vessels; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Calcimycin; Guinea Pigs; Humans; Hydroxyurea; Indomethacin; Lipoxygenase Inhibitors; Male; Pyrans; Quinolones; Rats; Skin

1995
Aqueous stability of SB 210661: kinetics and primary degradation mechanisms of an N-hydroxyurea-containing 5-lipoxygenase inhibitor.
    The Journal of pharmacy and pharmacology, 1998, Volume: 50, Issue:2

    Topics: Benzofurans; Drug Stability; Hydrogen-Ion Concentration; Hydroxyurea; Kinetics; Lipoxygenase Inhibitors; Urea; Water

1998
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