zileuton and a 78773
zileuton has been researched along with a 78773 in 8 studies
Research
Studies (8)
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 8 (100.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors
Authors | Studies |
---|---|
Basha, A; Bhatia, P; Bouska, JB; Brooks, CD; Craig, RA; Kolasa, T; Lanni, C; Martin, JG; Ratajczyk, JD; Stewart, AO | 1 |
Bell, RL; Bhatia, PA; Bouska, JB; Brooks, CD; Carter, GW; Craig, RA; DeNinno, SL; Holms, JH; Kerdesky, FA; Kolasa, T; Lanni, C; Maki, RG; Martin, JG; Martin, MB; Mazdiyasni, H; Moore, JL; Ratajczyk, JD; Rodriques, KE; Stewart, AO; Summers, JB; Young, PR | 1 |
Cai, X; Eckman, J; Hussoin, MS; Hwang, SB; Ip, SH; Killian, DB; Libertine-Garahan, L; Qian, C; Scannell, RT; Shen, TY; Yaeger, D; Yeh, CG | 1 |
Bell, RL; Bouska, JB; Brooks, DW; Carter, GW; Harris, RR; Lanni, C; Malo, PE; Otis, ER; Stewart, AO | 1 |
Bell, RL; Brooks, DW; Carter, GW; Hansen, R; Lanni, C; Malo, PE; Rubin, P; Stewart, AO | 1 |
Currie, JL; Isakson, PC; Rao, TS; Shaffer, AF | 1 |
Currie, JL; Isakson, PC; Kim, S; Rao, T; Shaffer, AF; Smith, WG; Thompson, JM | 1 |
Kearney, AS; McLoughlin, M; Palepu, NR | 1 |
Other Studies
8 other study(ies) available for zileuton and a 78773
Article | Year |
---|---|
(R)-(+)-N-[3-[5-[(4-fluorophenyl)methyl]-2-thienyl]-1-methyl- 2-propynyl]-N-hydroxyurea (ABT-761), a second-generation 5-lipoxygenase inhibitor.
Topics: Animals; Humans; Hydroxyurea; Lipoxygenase Inhibitors; Macaca fascicularis; Male; Microsomes, Liver; Rats; Rats, Sprague-Dawley; Stereoisomerism; Structure-Activity Relationship | 1995 |
Structure-activity relationships of N-hydroxyurea 5-lipoxygenase inhibitors.
Topics: Animals; Cells, Cultured; Drug Design; Enzyme Inhibitors; Furans; Glucuronates; Humans; Hydroxyurea; Lipoxygenase Inhibitors; Macaca fascicularis; Models, Chemical; Rats; Structure-Activity Relationship; Templates, Genetic; Thiophenes | 1997 |
(+/-)-trans-2-[3-methoxy-4-(4-chlorophenylthioethoxy)-5-(N-methyl-N- hydroxyureidyl)methylphenyl]-5-(3,4, 5-trimethoxyphenyl)tetrahydrofuran (CMI-392), a potent dual 5-lipoxygenase inhibitor and platelet-activating factor receptor antagonist.
Topics: Animals; Arachidonic Acid; Blood Platelets; Cell Membrane; CHO Cells; Cricetinae; Drug Evaluation, Preclinical; Edema; Enzyme Inhibitors; Furans; Hematocrit; Humans; Leukotriene B4; Lipoxygenase Inhibitors; Mice; Platelet Membrane Glycoproteins; Rats; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Urea | 1998 |
Optimization of the potency and duration of action of N-hydroxyurea 5-lipoxygenase inhibitors.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Haplorhini; Humans; Hydroxyurea; Leukotriene B4; Lipoxygenase Inhibitors; Mice; Rats; Stereoisomerism | 1995 |
Preclinical and clinical activity of zileuton and A-78773.
Topics: Animals; Bronchial Spasm; Guinea Pigs; Hydroxyurea; Inflammation; Leukotriene B4; Lipoxygenase Inhibitors; Lung; Male; Rats | 1993 |
Evaluation of 5-lipoxygenase inhibitors, zileuton, A-78773 and ICI-D-2138 in an ionophore (A-23187)-induced pleural inflammation model in the rat.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Calcimycin; Disease Models, Animal; Drug Evaluation, Preclinical; Eicosanoids; Hydroxyurea; Leukotrienes; Lipoxygenase Inhibitors; Male; Pleurisy; Prostaglandins; Pyrans; Quinolones; Rats; Rats, Sprague-Dawley | 1993 |
Characterization of 5-lipoxygenase inhibitors in biochemical and functional in vivo assays.
Topics: Animals; Antigens; Blood Vessels; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Calcimycin; Guinea Pigs; Humans; Hydroxyurea; Indomethacin; Lipoxygenase Inhibitors; Male; Pyrans; Quinolones; Rats; Skin | 1995 |
Aqueous stability of SB 210661: kinetics and primary degradation mechanisms of an N-hydroxyurea-containing 5-lipoxygenase inhibitor.
Topics: Benzofurans; Drug Stability; Hydrogen-Ion Concentration; Hydroxyurea; Kinetics; Lipoxygenase Inhibitors; Urea; Water | 1998 |