Page last updated: 2024-08-25

zidovudine triphosphate and lamivudine

zidovudine triphosphate has been researched along with lamivudine in 18 studies

Research

Studies (18)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (5.56)	18.2507
2000's	13 (72.22)	29.6817
2010's	4 (22.22)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Baba, M; De Clercq, E; Shi, M; Takao, S; Wang, X	1
Amblard, F; Bassit, L; Bondada, L; Coats, SJ; Detorio, M; Grier, J; Hernandez-Santiago, BI; Koontz, D; Mellors, JW; Rapp, KL; Schinazi, RF; Sluis-Cremer, N	1
Bassit, L; Coats, SJ; Detorio, M; Herman, BD; Mellors, JW; Nettles, JH; Obikhod, A; Schinazi, RF; Sluis-Cremer, N; Solomon, S; Tao, SJ; Zhang, HW	1
Arts, EJ; Gu, Z; Le Grice, SF; Marois, JP; Wainberg, MA	1
Klarmann, GJ; North, TW; Preston, BD; Schinazi, RF; Smith, RA	1
García, H; Rodriguez, JF; Rodriguez, JL; Rosario, O; Santana, J	1
Anderson, PL; Brundage, RC; Bushman, LR; Fletcher, CV; Kakuda, TN; Kawle, SP; Remmel, RP; Weller, D	1
Darque, A; Moore, JD; Sommadossi, JP; Valette, G; Zhou, XJ	1
Copeland, WC; Lim, SE	1
Duan, C; Kuritzkes, DR; McHenry, CS; Petropoulos, CJ; Poticha, D; Stoeckli, TC; Whitcomb, JM	1
Hurwitz, SJ; Schinazi, RF	1
Anderson, KS; Feng, JY; Furman, PA; Jeffrey, JL; Qi, CC	1
Anderson, PL; Bushman, LR; Fletcher, CV; Gerber, J; King, T; Meditz, A; Predhomme, J; Zheng, JH	1
Acosta, EP; Bassett, R; Eron, JJ; Fischl, MA; Johnson, VA; Kuritzkes, DR; Long, MC; Moore, JD; Sommadossi, JP	1
Bénech, H; Dehée, A; Dollfus, C; Durand-Gasselin, L; Garbarg-Chenon, A; Grassi, J; Leverger, G; Pruvost, A; Tabone, MD; Vaudre, G	1
Anderson, PL; Bushman, LR; Gardner, EM; Klein, B; Lichtenstein, K; Mawhinney, S; Meditz, A; Predhomme, J; Rower, JE; Zheng, JH	1
Barreto-de-Souza, V; Frolova, S; Karpenko, I; Khandazhinskaya, A; Kochetkov, S; Margolis, L; Vanpouille, C; Zicari, S	1
Bridges, AS; Cohen, MS; Dumond, JB; Fiscus, SA; Forrest, A; Kashuba, AD; Kendrick, R; Reddy, YS; Troiani, L; Yang, KH	1

Trials

1 trial(s) available for zidovudine triphosphate and lamivudine

Article	Year
Zidovudine triphosphate and lamivudine triphosphate concentration-response relationships in HIV-infected persons. AIDS (London, England), 2000, Sep-29, Volume: 14, Issue:14 Topics: Adolescent; Adult; Aged; Anti-HIV Agents; CD4 Lymphocyte Count; Cytidine Triphosphate; Dideoxynucleotides; Dose-Response Relationship, Drug; Drug Therapy, Combination; HIV; HIV Infections; Humans; Lamivudine; Leukocytes, Mononuclear; Middle Aged; Prospective Studies; Regression Analysis; Reverse Transcriptase Inhibitors; RNA, Viral; Thymine Nucleotides; Zidovudine	2000

Article

Year

Zidovudine triphosphate and lamivudine triphosphate concentration-response relationships in HIV-infected persons.

AIDS (London, England), 2000, Sep-29, Volume: 14, Issue:14

Topics: Adolescent; Adult; Aged; Anti-HIV Agents; CD4 Lymphocyte Count; Cytidine Triphosphate; Dideoxynucleotides; Dose-Response Relationship, Drug; Drug Therapy, Combination; HIV; HIV Infections; Humans; Lamivudine; Leukocytes, Mononuclear; Middle Aged; Prospective Studies; Regression Analysis; Reverse Transcriptase Inhibitors; RNA, Viral; Thymine Nucleotides; Zidovudine

2000

Other Studies

17 other study(ies) available for zidovudine triphosphate and lamivudine

Article	Year
Selective inhibition of porcine endogenous retrovirus replication in human cells by acyclic nucleoside phosphonates. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:7 Topics: Adenine; Amino Acid Sequence; Animals; Antiviral Agents; Catalysis; Cell Line; Dose-Response Relationship, Drug; Endogenous Retroviruses; HIV-1; Humans; Kidney; Molecular Sequence Data; Organophosphonates; Polymerase Chain Reaction; Protein Structure, Tertiary; Reverse Transcriptase Inhibitors; Stavudine; Swine; Swine, Miniature; Tenofovir; Virus Replication; Zidovudine	2007
Anti-human immunodeficiency virus activity, cross-resistance, cytotoxicity, and intracellular pharmacology of the 3'-azido-2',3'-dideoxypurine nucleosides. Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:9 Topics: Anti-HIV Agents; Cell Line, Tumor; Cell Survival; Cells, Cultured; Dideoxynucleosides; HIV Infections; HIV-1; Humans; Molecular Structure; Reverse Transcriptase Inhibitors	2009
Synthesis, antiviral activity, cytotoxicity and cellular pharmacology of l-3'-azido-2',3'-dideoxypurine nucleosides. European journal of medicinal chemistry, 2011, Volume: 46, Issue:9 Topics: Antiviral Agents; Cell Line; Glycosylation; Hepatitis B virus; HIV-1; Humans; Kinetics; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Microwaves; Models, Molecular; Nucleosides; Reverse Transcriptase Inhibitors; Spectrometry, Mass, Electrospray Ionization	2011
Effects of 3'-deoxynucleoside 5'-triphosphate concentrations on chain termination by nucleoside analogs during human immunodeficiency virus type 1 reverse transcription of minus-strand strong-stop DNA. Journal of virology, 1996, Volume: 70, Issue:2 Topics: Antiviral Agents; Base Sequence; Cells, Cultured; Didanosine; Dideoxynucleotides; DNA, Viral; HIV-1; Humans; Lamivudine; Molecular Sequence Data; Nucleic Acid Conformation; Nucleosides; Nucleotides; Phytohemagglutinins; RNA, Viral; Thymine Nucleotides; Transcription, Genetic; Zalcitabine; Zidovudine	1996
Site-specific incorporation of nucleoside analogs by HIV-1 reverse transcriptase and the template grip mutant P157S. Template interactions influence substrate recognition at the polymerase active site. The Journal of biological chemistry, 2000, Jan-07, Volume: 275, Issue:1 Topics: Catalytic Domain; Cytidine Triphosphate; Dideoxynucleotides; Dose-Response Relationship, Drug; Drug Resistance; HIV Reverse Transcriptase; HIV-1; Lamivudine; Mutation; Proline; Reverse Transcriptase Inhibitors; Thionucleosides; Thiophenes; Thymine Nucleotides; Transcription, Genetic; Zalcitabine; Zidovudine	2000
Simultaneous quantitation of intracellular zidovudine and lamivudine triphosphates in human immunodeficiency virus-infected individuals. Antimicrobial agents and chemotherapy, 2000, Volume: 44, Issue:11 Topics: Anti-HIV Agents; Chromatography, Ion Exchange; Cytidine Triphosphate; Dideoxynucleotides; HIV Infections; Humans; Lamivudine; Reference Standards; Thymine Nucleotides; Zidovudine	2000
Simultaneous quantitation of the 5'-triphosphate metabolites of zidovudine, lamivudine, and stavudine in peripheral mononuclear blood cells of HIV infected patients by high-performance liquid chromatography tandem mass spectrometry. Journal of the American Society for Mass Spectrometry, 2000, Volume: 11, Issue:12 Topics: Anti-HIV Agents; Calibration; Chromatography, High Pressure Liquid; Cytidine Triphosphate; Dideoxynucleotides; Drug Therapy, Combination; HIV Infections; Humans; Lamivudine; Mass Spectrometry; Monocytes; Reference Standards; Sensitivity and Specificity; Stavudine; Thymine Nucleotides; Zidovudine	2000
Differential incorporation and removal of antiviral deoxynucleotides by human DNA polymerase gamma. The Journal of biological chemistry, 2001, Jun-29, Volume: 276, Issue:26 Topics: Anti-HIV Agents; Cytidine Triphosphate; Deoxyguanine Nucleotides; Deoxyribonucleotides; Dideoxynucleotides; DNA; DNA Polymerase gamma; DNA Replication; DNA-Directed DNA Polymerase; Exodeoxyribonucleases; Humans; Kinetics; Lamivudine; Nucleic Acid Synthesis Inhibitors; Reverse Transcriptase Inhibitors; Stavudine; Substrate Specificity; Thymine Nucleotides; Zalcitabine; Zidovudine	2001
Inhibition of purified recombinant reverse transcriptase from wild-type and zidovudine-resistant clinical isolates of human immunodeficiency virus type 1 by zidovudine, stavudine, and lamivudine triphosphates. The Journal of infectious diseases, 2001, Nov-15, Volume: 184, Issue:10 Topics: Anti-HIV Agents; Cytidine Triphosphate; Dideoxynucleotides; Dose-Response Relationship, Drug; Drug Resistance, Microbial; Escherichia coli; HIV Infections; HIV-1; Lamivudine; Recombinant Proteins; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Stavudine; Thymine Nucleotides; Transfection; Zidovudine	2001
Development of a pharmacodynamic model for HIV treatment with nucleoside reverse transcriptase and protease inhibitors. Antiviral research, 2002, Volume: 56, Issue:2 Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Cytidine Triphosphate; Dideoxynucleotides; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Models, Statistical; Reverse Transcriptase Inhibitors; Thymine Nucleotides; Viral Load; Zidovudine	2002
Dioxolane guanosine 5'-triphosphate, an alternative substrate inhibitor of wild-type and mutant HIV-1 reverse transcriptase. Steady state and pre-steady state kinetic analyses. The Journal of biological chemistry, 2003, May-23, Volume: 278, Issue:21 Topics: Acquired Immunodeficiency Syndrome; Cytidine Triphosphate; Deoxycytidine Monophosphate; Deoxyguanine Nucleotides; Dideoxynucleotides; Dioxolanes; DNA, Viral; Drug Resistance, Viral; Guanosine; Guanosine Triphosphate; HIV Reverse Transcriptase; HIV-1; Lamivudine; Mutation; Reverse Transcriptase Inhibitors; Substrate Specificity; Thymidine Monophosphate; Thymine Nucleotides; Zidovudine	2003
Concentrations of zidovudine- and lamivudine-triphosphate according to cell type in HIV-seronegative adults. AIDS (London, England), 2007, Sep-12, Volume: 21, Issue:14 Topics: Adult; Anti-HIV Agents; CD4-Positive T-Lymphocytes; Cytidine Triphosphate; Dideoxynucleotides; Drug Administration Schedule; Female; HIV Seronegativity; Humans; Lamivudine; Leukocytes, Mononuclear; Male; Middle Aged; Phosphorylation; Reverse Transcriptase Inhibitors; Thymine Nucleotides; Zidovudine	2007
Intracellular nucleoside triphosphate concentrations in HIV-infected patients on dual nucleoside reverse transcriptase inhibitor therapy. Antiviral therapy, 2007, Volume: 12, Issue:6 Topics: Anti-HIV Agents; Cytidine Triphosphate; Dideoxynucleotides; Drug Therapy, Combination; Female; HIV Infections; Humans; Lamivudine; Leukocytes, Mononuclear; Male; Reverse Transcriptase Inhibitors; Stavudine; Thymine Nucleotides; Zidovudine	2007
High levels of zidovudine (AZT) and its intracellular phosphate metabolites in AZT- and AZT-lamivudine-treated newborns of human immunodeficiency virus-infected mothers. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:7 Topics: Anti-HIV Agents; Dideoxynucleotides; Female; Follow-Up Studies; HIV Infections; Humans; Infant; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Leukocytes, Mononuclear; Male; Pregnancy; Pregnancy Complications, Infectious; Prospective Studies; Thymine Nucleotides; Zidovudine	2008
Effect of HIV-1 infection and sex on the cellular pharmacology of the antiretroviral drugs zidovudine and lamivudine. Antimicrobial agents and chemotherapy, 2012, Volume: 56, Issue:6 Topics: Adult; Anti-HIV Agents; Black or African American; Cytidine Triphosphate; Dideoxynucleotides; Female; HIV Infections; Humans; Lamivudine; Longitudinal Studies; Male; Prospective Studies; Sex Factors; Thymine Nucleotides; Zidovudine	2012
A new antiviral: chimeric 3TC-AZT phosphonate efficiently inhibits HIV-1 in human tissues ex vivo. Antiviral research, 2014, Volume: 109 Topics: Anti-HIV Agents; Dideoxynucleotides; Drug Evaluation, Preclinical; HIV Infections; HIV-1; Humans; In Vitro Techniques; Lamivudine; Palatine Tonsil; Thymine Nucleotides; Virus Replication; Zidovudine	2014
Pharmacokinetic Modeling of Lamivudine and Zidovudine Triphosphates Predicts Differential Pharmacokinetics in Seminal Mononuclear Cells and Peripheral Blood Mononuclear Cells. Antimicrobial agents and chemotherapy, 2015, Volume: 59, Issue:10 Topics: Adult; Anti-HIV Agents; Biological Availability; Biological Transport; Blood Cells; Computer Simulation; Cytidine Triphosphate; Dideoxynucleotides; HIV Infections; HIV-1; Humans; Lamivudine; Leukocytes, Mononuclear; Male; Models, Statistical; Semen; Thymine Nucleotides; Time Factors; Zidovudine	2015