Page last updated: 2024-08-25

zidovudine triphosphate and lamivudine triphosphate

zidovudine triphosphate has been researched along with lamivudine triphosphate in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's12 (80.00)29.6817
2010's3 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Boyle, NA; Brooks, JL; Bruice, TW; Chen, F; Cook, PD; Ewing, GJ; Fagan, P; Hurd, T; Leeds, JM; Prhavc, M; Rajwanshi, VK; Wang, G1
Mellors, JW; Radzio, J; Sheen, CW; Sluis-Cremer, N; Zelina, S1
Amblard, F; Bassit, L; Bondada, L; Coats, SJ; Detorio, M; Grier, J; Hernandez-Santiago, BI; Koontz, D; Mellors, JW; Rapp, KL; Schinazi, RF; Sluis-Cremer, N1
Bassit, L; Coats, SJ; Detorio, M; Herman, BD; Mellors, JW; Nettles, JH; Obikhod, A; Schinazi, RF; Sluis-Cremer, N; Solomon, S; Tao, SJ; Zhang, HW1
GarcĂ­a, H; Rodriguez, JF; Rodriguez, JL; Rosario, O; Santana, J1
Anderson, PL; Brundage, RC; Bushman, LR; Fletcher, CV; Kakuda, TN; Kawle, SP; Remmel, RP; Weller, D1
Darque, A; Moore, JD; Sommadossi, JP; Valette, G; Zhou, XJ1
Copeland, WC; Lim, SE1
Duan, C; Kuritzkes, DR; McHenry, CS; Petropoulos, CJ; Poticha, D; Stoeckli, TC; Whitcomb, JM1
Hurwitz, SJ; Schinazi, RF1
Anderson, KS; Feng, JY; Furman, PA; Jeffrey, JL; Qi, CC1
Anderson, PL; Bushman, LR; Fletcher, CV; Gerber, J; King, T; Meditz, A; Predhomme, J; Zheng, JH1
Acosta, EP; Bassett, R; Eron, JJ; Fischl, MA; Johnson, VA; Kuritzkes, DR; Long, MC; Moore, JD; Sommadossi, JP1
Anderson, PL; Bushman, LR; Gardner, EM; Klein, B; Lichtenstein, K; Mawhinney, S; Meditz, A; Predhomme, J; Rower, JE; Zheng, JH1
Bridges, AS; Cohen, MS; Dumond, JB; Fiscus, SA; Forrest, A; Kashuba, AD; Kendrick, R; Reddy, YS; Troiani, L; Yang, KH1

Trials

1 trial(s) available for zidovudine triphosphate and lamivudine triphosphate

ArticleYear
Zidovudine triphosphate and lamivudine triphosphate concentration-response relationships in HIV-infected persons.
    AIDS (London, England), 2000, Sep-29, Volume: 14, Issue:14

    Topics: Adolescent; Adult; Aged; Anti-HIV Agents; CD4 Lymphocyte Count; Cytidine Triphosphate; Dideoxynucleotides; Dose-Response Relationship, Drug; Drug Therapy, Combination; HIV; HIV Infections; Humans; Lamivudine; Leukocytes, Mononuclear; Middle Aged; Prospective Studies; Regression Analysis; Reverse Transcriptase Inhibitors; RNA, Viral; Thymine Nucleotides; Zidovudine

2000

Other Studies

14 other study(ies) available for zidovudine triphosphate and lamivudine triphosphate

ArticleYear
Synthesis of 2',3'-dideoxynucleoside 5'-alpha-P-borano-beta,gamma-(difluoromethylene)triphosphates and their inhibition of HIV-1 reverse transcriptase.
    Journal of medicinal chemistry, 2005, Apr-07, Volume: 48, Issue:7

    Topics: Animals; Anti-HIV Agents; Boron Compounds; Cattle; Deoxyribonucleotides; HIV Reverse Transcriptase; In Vitro Techniques; Reverse Transcriptase Inhibitors; Stereoisomerism

2005
Mechanisms by which the G333D mutation in human immunodeficiency virus type 1 Reverse transcriptase facilitates dual resistance to zidovudine and lamivudine.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:1

    Topics: Anti-HIV Agents; Drug Resistance, Multiple, Viral; HIV Reverse Transcriptase; HIV-1; Humans; Kinetics; Lamivudine; Models, Molecular; Mutation; Reverse Transcriptase Inhibitors; Thermodynamics; Zidovudine

2008
Anti-human immunodeficiency virus activity, cross-resistance, cytotoxicity, and intracellular pharmacology of the 3'-azido-2',3'-dideoxypurine nucleosides.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:9

    Topics: Anti-HIV Agents; Cell Line, Tumor; Cell Survival; Cells, Cultured; Dideoxynucleosides; HIV Infections; HIV-1; Humans; Molecular Structure; Reverse Transcriptase Inhibitors

2009
Synthesis, antiviral activity, cytotoxicity and cellular pharmacology of l-3'-azido-2',3'-dideoxypurine nucleosides.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:9

    Topics: Antiviral Agents; Cell Line; Glycosylation; Hepatitis B virus; HIV-1; Humans; Kinetics; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Microwaves; Models, Molecular; Nucleosides; Reverse Transcriptase Inhibitors; Spectrometry, Mass, Electrospray Ionization

2011
Simultaneous quantitation of intracellular zidovudine and lamivudine triphosphates in human immunodeficiency virus-infected individuals.
    Antimicrobial agents and chemotherapy, 2000, Volume: 44, Issue:11

    Topics: Anti-HIV Agents; Chromatography, Ion Exchange; Cytidine Triphosphate; Dideoxynucleotides; HIV Infections; Humans; Lamivudine; Reference Standards; Thymine Nucleotides; Zidovudine

2000
Simultaneous quantitation of the 5'-triphosphate metabolites of zidovudine, lamivudine, and stavudine in peripheral mononuclear blood cells of HIV infected patients by high-performance liquid chromatography tandem mass spectrometry.
    Journal of the American Society for Mass Spectrometry, 2000, Volume: 11, Issue:12

    Topics: Anti-HIV Agents; Calibration; Chromatography, High Pressure Liquid; Cytidine Triphosphate; Dideoxynucleotides; Drug Therapy, Combination; HIV Infections; Humans; Lamivudine; Mass Spectrometry; Monocytes; Reference Standards; Sensitivity and Specificity; Stavudine; Thymine Nucleotides; Zidovudine

2000
Differential incorporation and removal of antiviral deoxynucleotides by human DNA polymerase gamma.
    The Journal of biological chemistry, 2001, Jun-29, Volume: 276, Issue:26

    Topics: Anti-HIV Agents; Cytidine Triphosphate; Deoxyguanine Nucleotides; Deoxyribonucleotides; Dideoxynucleotides; DNA; DNA Polymerase gamma; DNA Replication; DNA-Directed DNA Polymerase; Exodeoxyribonucleases; Humans; Kinetics; Lamivudine; Nucleic Acid Synthesis Inhibitors; Reverse Transcriptase Inhibitors; Stavudine; Substrate Specificity; Thymine Nucleotides; Zalcitabine; Zidovudine

2001
Inhibition of purified recombinant reverse transcriptase from wild-type and zidovudine-resistant clinical isolates of human immunodeficiency virus type 1 by zidovudine, stavudine, and lamivudine triphosphates.
    The Journal of infectious diseases, 2001, Nov-15, Volume: 184, Issue:10

    Topics: Anti-HIV Agents; Cytidine Triphosphate; Dideoxynucleotides; Dose-Response Relationship, Drug; Drug Resistance, Microbial; Escherichia coli; HIV Infections; HIV-1; Lamivudine; Recombinant Proteins; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Stavudine; Thymine Nucleotides; Transfection; Zidovudine

2001
Development of a pharmacodynamic model for HIV treatment with nucleoside reverse transcriptase and protease inhibitors.
    Antiviral research, 2002, Volume: 56, Issue:2

    Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Cytidine Triphosphate; Dideoxynucleotides; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Models, Statistical; Reverse Transcriptase Inhibitors; Thymine Nucleotides; Viral Load; Zidovudine

2002
Dioxolane guanosine 5'-triphosphate, an alternative substrate inhibitor of wild-type and mutant HIV-1 reverse transcriptase. Steady state and pre-steady state kinetic analyses.
    The Journal of biological chemistry, 2003, May-23, Volume: 278, Issue:21

    Topics: Acquired Immunodeficiency Syndrome; Cytidine Triphosphate; Deoxycytidine Monophosphate; Deoxyguanine Nucleotides; Dideoxynucleotides; Dioxolanes; DNA, Viral; Drug Resistance, Viral; Guanosine; Guanosine Triphosphate; HIV Reverse Transcriptase; HIV-1; Lamivudine; Mutation; Reverse Transcriptase Inhibitors; Substrate Specificity; Thymidine Monophosphate; Thymine Nucleotides; Zidovudine

2003
Concentrations of zidovudine- and lamivudine-triphosphate according to cell type in HIV-seronegative adults.
    AIDS (London, England), 2007, Sep-12, Volume: 21, Issue:14

    Topics: Adult; Anti-HIV Agents; CD4-Positive T-Lymphocytes; Cytidine Triphosphate; Dideoxynucleotides; Drug Administration Schedule; Female; HIV Seronegativity; Humans; Lamivudine; Leukocytes, Mononuclear; Male; Middle Aged; Phosphorylation; Reverse Transcriptase Inhibitors; Thymine Nucleotides; Zidovudine

2007
Intracellular nucleoside triphosphate concentrations in HIV-infected patients on dual nucleoside reverse transcriptase inhibitor therapy.
    Antiviral therapy, 2007, Volume: 12, Issue:6

    Topics: Anti-HIV Agents; Cytidine Triphosphate; Dideoxynucleotides; Drug Therapy, Combination; Female; HIV Infections; Humans; Lamivudine; Leukocytes, Mononuclear; Male; Reverse Transcriptase Inhibitors; Stavudine; Thymine Nucleotides; Zidovudine

2007
Effect of HIV-1 infection and sex on the cellular pharmacology of the antiretroviral drugs zidovudine and lamivudine.
    Antimicrobial agents and chemotherapy, 2012, Volume: 56, Issue:6

    Topics: Adult; Anti-HIV Agents; Black or African American; Cytidine Triphosphate; Dideoxynucleotides; Female; HIV Infections; Humans; Lamivudine; Longitudinal Studies; Male; Prospective Studies; Sex Factors; Thymine Nucleotides; Zidovudine

2012
Pharmacokinetic Modeling of Lamivudine and Zidovudine Triphosphates Predicts Differential Pharmacokinetics in Seminal Mononuclear Cells and Peripheral Blood Mononuclear Cells.
    Antimicrobial agents and chemotherapy, 2015, Volume: 59, Issue:10

    Topics: Adult; Anti-HIV Agents; Biological Availability; Biological Transport; Blood Cells; Computer Simulation; Cytidine Triphosphate; Dideoxynucleotides; HIV Infections; HIV-1; Humans; Lamivudine; Leukocytes, Mononuclear; Male; Models, Statistical; Semen; Thymine Nucleotides; Time Factors; Zidovudine

2015