Compounds > zidovudine triphosphate
Page last updated: 2024-08-25

zidovudine triphosphate and foscarnet

zidovudine triphosphate has been researched along with foscarnet in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19901 (6.67)18.7374
1990's4 (26.67)18.2507
2000's8 (53.33)29.6817
2010's2 (13.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Brideau, RJ; Cudahy, MM; Homa, FL; Hopkins, TA; Knechtel, ML; Oien, NL; Pitts, TW; Poorman, RA; Schnute, ME; Wathen, MW; Wieber, JL1
Dornadula, G; Grobler, JA; Hazuda, DJ; Miller, MD; Rice, MR; Simcoe, AL1
Anderson, DJ; Brideau, RJ; Ciske, FL; Collier, SA; Cudahy, MM; Eggen, M; Genin, MJ; Hopkins, TA; Judge, TM; Kim, EJ; Knechtel, ML; Nair, SK; Nieman, JA; Oien, NL; Schnute, ME; Scott, A; Tanis, SP; Vaillancourt, VA; Wathen, MW; Wieber, JL1
Brideau, RJ; DiPaolo, BA; Hageman, MJ; Hopkins, TA; Knechtel, ML; Larsen, SD; Manninen, PR; Oien, NL; Rohrer, DC; Rush, BD; Schwende, FJ; Stefanski, KJ; Wathen, MW; Wieber, JL; Wilkinson, KF; Zamora, KM; Zhang, Z1
Brideau, RJ; Collier, SA; Cudahy, MM; Hopkins, TA; Knechtel, ML; Oien, NL; Sackett, RS; Schnute, ME; Scott, A; Stephan, ML; Wathen, MW; Wieber, JL1
Hopkins, TA; Knechtel, ML; Moon, MW; Oien, NL; Parker, TT; Perrault, WR; Stephanski, KJ; Strohbach, JW; Tanis, SP; Thaisrivongs, S; Wathen, MW; Wieber, JL1
Chen, K; Heasley, SE; Hopkins, TA; Knechtel, ML; Nair, SK; Nieman, JA; Nugent, RA; Oien, NL; Schultz, BL; Stephanski, KJ; Wathen, MW; Wieber, JL; Zerth, HM1
Kemp, SD; Larder, BA; Lowe, DM; Parmar, V1
Quan, K; Tao, P; Zhang, X1
Kurth, R; Löwer, J; Oberg, B; Vrang, L1
Cheng, YC; Gonzalez, CJ; Im, GJ; Tramontano, E1
Blackburn, EH; Strahl, C1
Boretto, J; Canard, B; Capony, JP; Lazaro, JB; Selmi, B1
Feuston, B; Getty, K; Hazuda, DJ; Krueger, J; Lewis, D; Miller, MD; Munshi, V; Parniak, MA; Shaw-Reid, CA1
Ansó, E; Cruchaga, C; Martínez-Irujo, JJ; Rouzaut, A1

Other Studies

15 other study(ies) available for zidovudine triphosphate and foscarnet

ArticleYear
4-Oxo-4,7-dihydrothieno[2,3-b]pyridines as non-nucleoside inhibitors of human cytomegalovirus and related herpesvirus polymerases.
    Journal of medicinal chemistry, 2005, Sep-08, Volume: 48, Issue:18

    Topics: Animals; Antiviral Agents; Cell Line; Cell Survival; Chlorocebus aethiops; Cytomegalovirus; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Exodeoxyribonucleases; Herpesvirus 1, Human; Herpesvirus 3, Human; Humans; Nucleic Acid Synthesis Inhibitors; Point Mutation; Pyridines; Pyridones; Structure-Activity Relationship; Thiophenes; Viral Plaque Assay; Viral Proteins

2005
HIV-1 reverse transcriptase plus-strand initiation exhibits preferential sensitivity to non-nucleoside reverse transcriptase inhibitors in vitro.
    The Journal of biological chemistry, 2007, Mar-16, Volume: 282, Issue:11

    Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Benzoxazoles; Cyclopropanes; DNA; Dose-Response Relationship, Drug; Drug Resistance, Viral; Enzyme Inhibitors; HIV Reverse Transcriptase; In Vitro Techniques; Inhibitory Concentration 50; Ligands; Models, Genetic; Oxazines; Pyridones; Reverse Transcriptase Inhibitors; Stochastic Processes; Transcription, Genetic; Virus Replication

2007
2-Aryl-2-hydroxyethylamine substituted 4-oxo-4,7-dihydrothieno[2,3-b]pyridines as broad-spectrum inhibitors of human herpesvirus polymerases.
    Bioorganic & medicinal chemistry letters, 2007, Jun-15, Volume: 17, Issue:12

    Topics: Antiviral Agents; Binding, Competitive; Cytomegalovirus; DNA-Directed DNA Polymerase; Enzyme Inhibitors; Ethylamines; Exodeoxyribonucleases; Herpes Zoster; Herpesviridae; Herpesvirus 1, Human; Herpesvirus 4, Human; Humans; Models, Chemical; Nucleic Acid Synthesis Inhibitors; Pyridines; Structure-Activity Relationship; Viral Proteins

2007
7-Oxo-4,7-dihydrothieno[3,2-b]pyridine-6-carboxamides: synthesis and biological activity of a new class of highly potent inhibitors of human cytomegalovirus DNA polymerase.
    Bioorganic & medicinal chemistry letters, 2007, Jul-15, Volume: 17, Issue:14

    Topics: Cytomegalovirus; Enzyme Inhibitors; Nucleic Acid Synthesis Inhibitors; Pyridines; Structure-Activity Relationship

2007
Synthesis of 4-oxo-4,7-dihydrofuro[2,3-b]pyridine-5-carboxamides with broad-spectrum human herpesvirus polymerase inhibition.
    Bioorganic & medicinal chemistry letters, 2008, Jul-15, Volume: 18, Issue:14

    Topics: Antiviral Agents; Chemistry, Pharmaceutical; Cytomegalovirus; Drug Design; Enzyme Inhibitors; Esters; Furans; Herpesviridae; Herpesvirus 3, Human; Herpesvirus 4, Human; Inhibitory Concentration 50; Models, Chemical; Molecular Conformation; Nucleic Acid Synthesis Inhibitors; Pyridones; Simplexvirus

2008
The design and development of 2-aryl-2-hydroxy ethylamine substituted 1H,7H-pyrido[1,2,3-de]quinoxaline-6-carboxamides as inhibitors of human cytomegalovirus polymerase.
    Bioorganic & medicinal chemistry letters, 2010, Mar-15, Volume: 20, Issue:6

    Topics: Antiviral Agents; Drug Design; Protease Inhibitors; Quinoxalines; Serine Endopeptidases

2010
Modifications of C-2 on the pyrroloquinoline template aimed at the development of potent herpesvirus antivirals with improved aqueous solubility.
    Bioorganic & medicinal chemistry letters, 2010, May-15, Volume: 20, Issue:10

    Topics: Antiviral Agents; Cytomegalovirus; DNA-Directed DNA Polymerase; Herpesviridae; Herpesvirus 1, Human; Herpesvirus 3, Human; Humans; Nucleic Acid Synthesis Inhibitors; Pyrroles; Quinolines; Solubility; Structure-Activity Relationship

2010
Mutational analysis of two conserved sequence motifs in HIV-1 reverse transcriptase.
    FEBS letters, 1991, May-06, Volume: 282, Issue:2

    Topics: Amino Acid Sequence; Dideoxynucleotides; DNA Mutational Analysis; Foscarnet; HIV-1; In Vitro Techniques; Kinetics; Molecular Sequence Data; Phosphonoacetic Acid; Recombinant Proteins; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Structure-Activity Relationship; Thymine Nucleotides; Zidovudine

1991
The characterization of EIAV reverse transcriptase and its inhibition by 5'-triphosphates of 2'-deoxyuridine analogs, PFA and PAA.
    Proceedings of the Chinese Academy of Medical Sciences and the Peking Union Medical College = Chung-kuo i hsueh k'o hsueh yuan, Chung-kuo hsieh ho i k'o ta hsueh hsueh pao, 1990, Volume: 5, Issue:3

    Topics: Antiviral Agents; Dideoxynucleotides; Foscarnet; HIV; Infectious Anemia Virus, Equine; Phosphonoacetic Acid; RNA-Directed DNA Polymerase; Thymine Nucleotides; Zidovudine

1990
Reverse transcriptases from human immunodeficiency virus type 1 (HIV-1), HIV-2, and simian immunodeficiency virus (SIVMAC) are susceptible to inhibition by foscarnet and 3'-azido-3'-deoxythymidine triphosphate.
    Antimicrobial agents and chemotherapy, 1988, Volume: 32, Issue:11

    Topics: Animals; Dideoxynucleotides; Foscarnet; HIV-1; HIV-2; Humans; Organophosphorus Compounds; Phosphonoacetic Acid; Reverse Transcriptase Inhibitors; Simian Immunodeficiency Virus; Thymine Nucleotides; Zidovudine

1988
Identification of the amino acid in the human immunodeficiency virus type 1 reverse transcriptase involved in the pyrophosphate binding of antiviral nucleoside triphosphate analogs and phosphonoformate. Implications for multiple drug resistance.
    Biochemical pharmacology, 1993, Dec-14, Volume: 46, Issue:12

    Topics: Amino Acids; Antiviral Agents; Binding Sites; Dideoxynucleotides; Diphosphates; Drug Resistance, Microbial; Foscarnet; HIV Reverse Transcriptase; HIV-1; Kinetics; Recombinant Proteins; RNA-Directed DNA Polymerase; Thymine Nucleotides; Zidovudine

1993
Effects of reverse transcriptase inhibitors on telomere length and telomerase activity in two immortalized human cell lines.
    Molecular and cellular biology, 1996, Volume: 16, Issue:1

    Topics: Antiviral Agents; Arabinonucleosides; Cell Division; Cell Line; Dideoxynucleosides; Dideoxynucleotides; DNA; Drug Interactions; Foscarnet; Humans; Oligonucleotide Probes; Repetitive Sequences, Nucleic Acid; Reverse Transcriptase Inhibitors; Telomerase; Telomere; Thymine Nucleotides; Zidovudine

1996
Phosphorylation of AZT-resistant human immunodeficiency virus type 1 reverse transcriptase by casein kinase II in vitro: effects on inhibitor sensitivity.
    Biochemical and biophysical research communications, 2000, Aug-18, Volume: 275, Issue:1

    Topics: Amino Acid Motifs; Amino Acid Sequence; Binding Sites; Casein Kinase II; Consensus Sequence; Dideoxynucleotides; DNA; DNA Repair; Drug Resistance, Microbial; Enzyme Activation; Foscarnet; HIV Reverse Transcriptase; HIV-1; Humans; Mutation; Peptide Mapping; Phosphoric Monoester Hydrolases; Phosphorylation; Phosphoserine; Phosphothreonine; Protein Serine-Threonine Kinases; Recombinant Proteins; Reverse Transcriptase Inhibitors; Substrate Specificity; Thymine Nucleotides; Zidovudine

2000
Dissecting the effects of DNA polymerase and ribonuclease H inhibitor combinations on HIV-1 reverse-transcriptase activities.
    Biochemistry, 2005, Feb-08, Volume: 44, Issue:5

    Topics: Anti-HIV Agents; Binding Sites; Butyrates; Catalysis; Dideoxynucleotides; DNA-Directed DNA Polymerase; Drug Combinations; Drug Synergism; Foscarnet; HIV Reverse Transcriptase; Hydrolysis; Kinetics; Nucleic Acid Synthesis Inhibitors; Oxazines; Reverse Transcriptase Inhibitors; Ribonuclease H; Thiophenes; Thymine Nucleotides; Zidovudine

2005
Selective excision of chain-terminating nucleotides by HIV-1 reverse transcriptase with phosphonoformate as substrate.
    The Journal of biological chemistry, 2006, Sep-22, Volume: 281, Issue:38

    Topics: Antiviral Agents; Binding Sites; Catalysis; Dideoxynucleotides; Foscarnet; HIV Reverse Transcriptase; Reverse Transcriptase Inhibitors; Thymine Nucleotides; Zidovudine

2006