Compounds > zidovudine triphosphate
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zidovudine triphosphate and efavirenz

zidovudine triphosphate has been researched along with efavirenz in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (80.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dornadula, G; Grobler, JA; Hazuda, DJ; Miller, MD; Rice, MR; Simcoe, AL1
Elgaher, WA; Hartmann, RW; Haupenthal, J; Mély, Y; Pires, M; Real, E; Saladini, F; Sharma, KK1
Maga, G; Pregnolato, M; Salvetti, R; Spadari, S; Ubiali, D1
Gosselin, G; Hübscher, U; Maga, G; Pregnolato, M; Spadari, S; Ubiali, D1
Andréola, M; Cruchaga, C; Martínez-Irujo, JJ; Odriozola, L; Tarrago-Litvak, L1

Other Studies

5 other study(ies) available for zidovudine triphosphate and efavirenz

ArticleYear
HIV-1 reverse transcriptase plus-strand initiation exhibits preferential sensitivity to non-nucleoside reverse transcriptase inhibitors in vitro.
    The Journal of biological chemistry, 2007, Mar-16, Volume: 282, Issue:11

    Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Benzoxazoles; Cyclopropanes; DNA; Dose-Response Relationship, Drug; Drug Resistance, Viral; Enzyme Inhibitors; HIV Reverse Transcriptase; In Vitro Techniques; Inhibitory Concentration 50; Ligands; Models, Genetic; Oxazines; Pyridones; Reverse Transcriptase Inhibitors; Stochastic Processes; Transcription, Genetic; Virus Replication

2007
Discovery and Structure-Based Optimization of 2-Ureidothiophene-3-carboxylic Acids as Dual Bacterial RNA Polymerase and Viral Reverse Transcriptase Inhibitors.
    Journal of medicinal chemistry, 2016, Aug-11, Volume: 59, Issue:15

    Topics: Anti-Bacterial Agents; Anti-HIV Agents; Carboxylic Acids; DNA-Directed RNA Polymerases; Dose-Response Relationship, Drug; Drug Discovery; Enzyme Inhibitors; Escherichia coli; HEK293 Cells; HeLa Cells; HIV; Humans; Microbial Sensitivity Tests; Molecular Structure; RNA-Directed DNA Polymerase; Structure-Activity Relationship; Thiophenes

2016
Selective interaction of the human immunodeficiency virus type 1 reverse transcriptase nonnucleoside inhibitor efavirenz and its thio-substituted analog with different enzyme-substrate complexes.
    Antimicrobial agents and chemotherapy, 2000, Volume: 44, Issue:5

    Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Binding, Competitive; Catalytic Domain; Cyclopropanes; Dideoxynucleotides; Drug Synergism; HIV Reverse Transcriptase; HIV-1; Humans; Kinetics; Oxazines; Reverse Transcriptase Inhibitors; Thymine Nucleotides; Zidovudine

2000
Potentiation of inhibition of wild-type and mutant human immunodeficiency virus type 1 reverse transcriptases by combinations of nonnucleoside inhibitors and d- and L-(beta)-dideoxynucleoside triphosphate analogs.
    Antimicrobial agents and chemotherapy, 2001, Volume: 45, Issue:4

    Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Dideoxynucleosides; Dideoxynucleotides; DNA Replication; DNA, Viral; Dose-Response Relationship, Drug; Drug Resistance, Microbial; Drug Synergism; HIV Reverse Transcriptase; Humans; Inhibitory Concentration 50; Mutation; Nevirapine; Oxazines; Reverse Transcriptase Inhibitors; Stereoisomerism; Thymine Nucleotides; Zidovudine

2001
Inhibition of phosphorolysis catalyzed by HIV-1 reverse transcriptase is responsible for the synergy found in combinations of 3'-azido-3'-deoxythymidine with nonnucleoside inhibitors.
    Biochemistry, 2005, Mar-08, Volume: 44, Issue:9

    Topics: Alkynes; Benzoxazines; Binding Sites; Catalysis; Cyclopropanes; Dideoxynucleotides; DNA Primers; Drug Combinations; Drug Synergism; Enzyme Stability; HIV Reverse Transcriptase; Nevirapine; Oxazines; Phosphoric Acids; Pyridones; Reverse Transcriptase Inhibitors; Templates, Genetic; Thymine Nucleotides; Zidovudine

2005