zidovudine has been researched along with uridine in 25 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (4.00) | 18.7374 |
| 1990's | 12 (48.00) | 18.2507 |
| 2000's | 6 (24.00) | 29.6817 |
| 2010's | 6 (24.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
| Hung, K; Patel, SS; Szebeni, J; Wahl, LM; Weinstein, JN | 1 |
| Calabresi, P; Chu, SH; Darnowski, JW; Falcone, A; St Clair, MH; Wiemann, MC | 1 |
| Brunetti, I; Calabresi, P; Chu, SH; Darnowski, JW; Falcone, A; Ruprecht, RM | 1 |
| Carlisle, R; Schinazi, RF; Sommadossi, JP; Zhou, Z | 1 |
| Allegra, CJ; Grogan, L; Sotos, GA | 1 |
| Alvarez, R; Balzarini, J; Camarasa, MJ; De Clercq, E; Jimeno, ML; San-Félix, A; Velázquez, S | 1 |
| Agarwal, RP; Bansal, M; Gupta, V; He, J | 1 |
| Cass, CE; Huang, QQ; Paterson, AR; Ritzel, MW; Yao, SY; Young, JD | 1 |
| Balzarini, J | 1 |
| Ellemunter, H; Gschwentner, M; Huemer, H; Laich, A; Nagl, UO; Pinggera, GM; Ritter, M; Schmarda, A; Susanna, A; Wöll, E | 1 |
| Cass, CE; Yao, SY; Young, JD | 1 |
| Faraj, A; Gosselin, G; Imbach, JL; Perigaud, C; Schinazi, RF; Sommadossi, JP; Xie, MY | 1 |
| Balzarini, J; Camarasa, MJ; Chamorro, C; De Clercq, E; Jimeno, ML; Tuñón, V; Velázquez, S | 1 |
| Bendayan, R; Hong, M; Schlichter, L | 1 |
| Aubertin, AM; Benzaria, S; Ciurea, A; Delbederi, Z; Fossey, C; Gavriliu, D; Kirn, A; Ladurée, D; Lelong, B | 1 |
| Beauvoit, B; Bonnet, J; Deveaud, C; Kirschner, J; Lebrecht, D; Walker, UA | 1 |
| Aweeka, F; Jayewardene, AL; Lebrecht, D; Venhoff, AC; Venhoff, N; Walker, UA | 1 |
| Iams, TA; McKee, EE; Morris, GW; Slepchenko, KG | 1 |
| Saada, A | 1 |
| Beauvoit, B; Bonnet, J; Deveaud, C; Kirschner, J; Lebrecht, D; Müller, K; Venhoff, AC; Venhoff, N; Walker, UA | 1 |
| Balcarek, K; Beauvoit, B; Bonnet, J; Deveaud, C; Kirschner, J; Lebrecht, D; Venhoff, AC; Venhoff, N; Walker, UA | 1 |
| Goltz, D; Jauch, C; Schott, H; Schott, TC; Schwendener, RA | 1 |
| Eriksson, S; Sun, R; Wang, L | 1 |
2 review(s) available for zidovudine and uridine
| Article | Year |
|---|---|
Preclinical and clinical aspects of biomodulation of 5-fluorouracil.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Cisplatin; Colorectal Neoplasms; DNA, Neoplasm; Fluorouracil; Humans; Idoxuridine; Immunologic Factors; Interferons; Leucovorin; Methotrexate; Mice; Phosphonoacetic Acid; RNA, Neoplasm; Uracil; Uridine; Zidovudine | 1994 |
Metabolism and mechanism of antiretroviral action of purine and pyrimidine derivatives.
Topics: Animals; Antiviral Agents; Dideoxyadenosine; Dideoxynucleosides; Humans; Lamivudine; Purines; Pyrimidines; Retroviridae; Spiro Compounds; Stavudine; Thymidine; Uridine; Zalcitabine; Zidovudine | 1994 |
1 trial(s) available for zidovudine and uridine
| Article | Year |
|---|---|
Pharmacokinetics of zidovudine and lamivudine during oral uridine supplementation with NucleomaxX.
Topics: Administration, Oral; Area Under Curve; Double-Blind Method; Female; HIV Infections; Humans; Lamivudine; Male; Placebos; Reverse Transcriptase Inhibitors; Uridine; Zidovudine | 2008 |
22 other study(ies) available for zidovudine and uridine
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |
Effects of thymidine and uridine on the phosphorylation of 3'-azido-3'-deoxythymidine (zidovudine) in human mononuclear cells.
Topics: Bone Marrow; Bone Marrow Cells; Dose-Response Relationship, Drug; Humans; Leukocytes, Mononuclear; Macrophages; Phosphorylation; Thymidine; Thymidine Kinase; Tritium; Uridine; Zidovudine | 1991 |
Benzylacyclouridine reverses azidothymidine-induced marrow suppression without impairment of anti-human immunodeficiency virus activity.
Topics: Anemia; Animals; Cell Line; Cytopathogenic Effect, Viral; Female; HIV; Leukopenia; Mice; Mice, Inbred BALB C; Uracil; Uridine; Zidovudine | 1990 |
Different effect of benzylacyclouridine on the toxic and therapeutic effects of azidothymidine in mice.
Topics: Acquired Immunodeficiency Syndrome; Anemia; Animals; Dose-Response Relationship, Drug; Female; Kinetics; Leukemia, Experimental; Leukopenia; Mice; Mice, Inbred BALB C; Rauscher Virus; Uracil; Uridine; Zidovudine | 1990 |
Uridine reverses the toxicity of 3'-azido-3'-deoxythymidine in normal human granulocyte-macrophage progenitor cells in vitro without impairment of antiretroviral activity.
Topics: Antiviral Agents; Cytidine; HIV; Humans; In Vitro Techniques; Macrophages; Stem Cells; Thymidine; Uridine; Virus Replication; Zidovudine | 1988 |
Synthesis and anti-HIV activity of [AZT]-[TSAO-T] and [AZT]-[HEPT] dimers as potential multifunctional inhibitors of HIV-1 reverse transcriptase.
Topics: Antiviral Agents; Cell Line; HIV Reverse Transcriptase; HIV-1; Humans; Polymers; Reverse Transcriptase Inhibitors; Spiro Compounds; Thymidine; Thymine; Uridine; Zidovudine | 1995 |
Effect of long-term zidovudine exposure on salvage and de novo purine and pyrimidine nucleotide syntheses.
Topics: Bicarbonates; Cell Line; Formates; Humans; Hypoxanthine; Hypoxanthines; Purine Nucleotides; Pyrimidine Nucleotides; Time Factors; Uridine; Zidovudine | 1995 |
Cloning and functional expression of a complementary DNA encoding a mammalian nucleoside transport protein.
Topics: Amino Acid Sequence; Animals; Base Sequence; Carrier Proteins; Cloning, Molecular; DNA, Complementary; Humans; Membrane Proteins; Molecular Sequence Data; Nucleoside Transport Proteins; Nucleosides; Oocytes; Protein Conformation; Rats; Uridine; Xenopus; Zalcitabine; Zidovudine | 1994 |
Antiviral drugs from the nucleoside analog family block volume-activated chloride channels.
Topics: 3T3 Cells; Acyclovir; Animals; Antiviral Agents; Cell Size; Chloride Channels; Humans; Mice; Patch-Clamp Techniques; Thymidine; Tumor Cells, Cultured; Uridine; Zidovudine | 1995 |
Transport of the antiviral nucleoside analogs 3'-azido-3'-deoxythymidine and 2',3'-dideoxycytidine by a recombinant nucleoside transporter (rCNT) expressed in Xenopus laevis oocytes.
Topics: Animals; Antiviral Agents; Biological Transport; Carrier Proteins; Dose-Response Relationship, Drug; Female; Intestinal Absorption; Membrane Proteins; Nucleoside Transport Proteins; Probenecid; Rats; Recombinant Proteins; Uridine; Xenopus laevis; Zalcitabine; Zidovudine | 1996 |
Selective protection of toxicity of 2',3'-dideoxypyrimidine nucleoside analogs by beta-D-uridine in human granulocyte-macrophage progenitor cells.
Topics: Antiviral Agents; Bone Marrow Cells; Cells, Cultured; Dideoxynucleosides; Granulocytes; Hematopoietic Stem Cells; HIV; Humans; Macrophages; Molecular Structure; Uridine; Zidovudine | 1996 |
Potential multifunctional inhibitors of HIV-1 reverse transcriptase. Novel [AZT]-[TSAO-T] and [d4T]-[TSAO-T] heterodimers modified in the linker and in the dideoxynucleoside region.
Topics: Anti-HIV Agents; Cell Line; Dimerization; HIV-1; HIV-2; Humans; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Reverse Transcriptase Inhibitors; Spectrometry, Mass, Fast Atom Bombardment; Spiro Compounds; Stavudine; Thymidine; Uridine; Zidovudine | 1999 |
A Na(+)-dependent nucleoside transporter in microglia.
Topics: Adenosine; Animals; Carrier Proteins; Cell Size; Cells, Cultured; Cytidine; Dideoxynucleosides; Dose-Response Relationship, Drug; Guanosine; Membrane Proteins; Microglia; Nucleic Acid Probes; Nucleoside Transport Proteins; Rats; Rats, Wistar; Sodium; Thymidine; Time Factors; Uridine; Zidovudine | 2000 |
Synthesis of 5-alkenylated D4T analogues via the Pd-catalyzed cross-coupling reaction.
Topics: Catalysis; Cell Line; Chromatography, Thin Layer; HIV-1; Humans; Magnetic Resonance Spectroscopy; Palladium; RNA-Directed DNA Polymerase; Spectroscopy, Fourier Transform Infrared; Stavudine; Uridine; Zidovudine | 2001 |
Uridine supplementation antagonizes zidovudine-induced mitochondrial myopathy and hyperlactatemia in mice.
Topics: Animals; DNA, Mitochondrial; Drug Interactions; Electron Transport; Electron Transport Complex IV; Gene Dosage; Lactates; Lipid Peroxidation; Male; Malondialdehyde; Mice; Mice, Inbred BALB C; Mitochondrial Myopathies; Muscle, Skeletal; Reverse Transcriptase Inhibitors; Triglycerides; Uridine; Zalcitabine; Zidovudine | 2008 |
Origin of pyrimidine deoxyribonucleotide pools in perfused rat heart: implications for 3'-azido-3'-deoxythymidine-dependent cardiotoxicity.
Topics: Animals; Chromatography, High Pressure Liquid; Cytidine; Cytidine Triphosphate; Deoxyadenine Nucleotides; Deoxycytidine; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; Deoxyuridine; Heart; In Vitro Techniques; Male; Perfusion; Phosphorylation; Pyrimidine Nucleotides; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Inhibitors; Thymine Nucleotides; Uracil; Uridine; Uridine Monophosphate; Uridine Triphosphate; Zidovudine | 2009 |
Fishing in the (deoxyribonucleotide) pool.
Topics: Animals; Antimetabolites; Cytidine; Cytidine Triphosphate; Deoxyadenine Nucleotides; Deoxycytidine; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; Deoxyuridine; Heart; Humans; Mitochondria; Mitochondrial Diseases; Models, Biological; Phosphorylation; Pyrimidine Nucleotides; Rats; Thymine Nucleotides; Uracil; Uridine; Uridine Monophosphate; Uridine Triphosphate; Zidovudine | 2009 |
Oral uridine supplementation antagonizes the peripheral neuropathy and encephalopathy induced by antiretroviral nucleoside analogues.
Topics: Administration, Oral; Animals; Anti-HIV Agents; DNA, Mitochondrial; Drug Interactions; Lipid Peroxidation; Male; Mice; Mice, Inbred BALB C; Mitochondrial Encephalomyopathies; Mitochondrial Myopathies; Uridine; Zalcitabine; Zidovudine | 2010 |
Role of pyrimidine depletion in the mitochondrial cardiotoxicity of nucleoside analogue reverse transcriptase inhibitors.
Topics: Animals; Anti-HIV Agents; Cardiomyopathies; Cardiotoxins; Dietary Supplements; DNA Copy Number Variations; DNA, Mitochondrial; Electron Transport Complex IV; Heart; HIV Infections; Mice; Mice, Inbred BALB C; Mitochondria, Heart; Mutation; Nucleosides; Pyrimidines; Reactive Oxygen Species; Reverse Transcriptase Inhibitors; Uridine; Zalcitabine; Zidovudine | 2010 |
N⁴-[Alkyl-(hydroxyphosphono)phosphonate]-cytidine-new drugs covalently linking antimetabolites (5-FdU, araU or AZT) with bone-targeting bisphosphonates (alendronate or pamidronate).
Topics: Alendronate; Animals; Antimetabolites, Antineoplastic; Arabinofuranosyluracil; Bone and Bones; Bone Density Conservation Agents; Cell Line, Tumor; Cytidine; Diphosphonates; Drug Screening Assays, Antitumor; Durapatite; Fluorouracil; Humans; Macrophages; Mice; Pamidronate; Uridine; Zidovudine | 2011 |
Zidovudine induces downregulation of mitochondrial deoxynucleoside kinases: implications for mitochondrial toxicity of antiviral nucleoside analogs.
Topics: Antimetabolites; Antiviral Agents; Cell Line, Tumor; DNA Replication; DNA, Mitochondrial; Down-Regulation; Humans; Mitochondria; Nucleosides; Oxidants; Oxidative Stress; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Reactive Oxygen Species; Thymidine Kinase; Uridine; Zidovudine | 2014 |