Compounds > zidovudine
Page last updated: 2024-08-23

zidovudine and uridine diphosphate glucuronic acid

zidovudine has been researched along with uridine diphosphate glucuronic acid in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (16.67)18.2507
2000's2 (33.33)29.6817
2010's2 (33.33)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Chu, CK; Cretton, EM; Goudgaon, NM; Schinazi, RF; Sommadossi, JP; Xie, MY1
Collier, AC; Keelan, JA; Mitchell, MD; Paxton, JW; Tingle, MD; Van Zijl, PE1
Kamimura, H; Mano, Y; Usui, T1
Finel, M; Manevski, N; Moreolo, PS; Yli-Kauhaluoma, J1
Deng, JP; Fang, ZZ; Hu, CM; Li, G; Li, HR; Tu, YY; Wang, L; Yao, JJ; Yuan, J; Zhang, YS1
Chau, N; McKinnon, RA; Miners, JO; Nair, PC1

Other Studies

6 other study(ies) available for zidovudine and uridine diphosphate glucuronic acid

ArticleYear
Catabolic disposition of 3'-azido-2',3'-dideoxyuridine in hepatocytes with evidence of azido reduction being a general catabolic pathway of 3'-azido-2',3'-dideoxynucleosides.
    Biochemical pharmacology, 1992, Sep-01, Volume: 44, Issue:5

    Topics: Animals; Antiviral Agents; Azides; Chromatography, High Pressure Liquid; Deoxyuridine; Dideoxynucleosides; Glucuronates; Hematopoietic Stem Cells; Microsomes, Liver; NADP; Oxidation-Reduction; Rats; Rats, Inbred Strains; Ribonucleosides; Uridine Diphosphate Glucuronic Acid; Zalcitabine; Zidovudine

1992
Human placental glucuronidation and transport of 3'azido-3'-deoxythymidine and uridine diphosphate glucuronic acid.
    Drug metabolism and disposition: the biological fate of chemicals, 2004, Volume: 32, Issue:8

    Topics: Biological Transport; Dose-Response Relationship, Drug; Female; Humans; Placenta; Uridine Diphosphate Glucuronic Acid; Zidovudine

2004
Comparison of inhibition potentials of drugs against zidovudine glucuronidation in rat hepatocytes and liver microsomes.
    Drug metabolism and disposition: the biological fate of chemicals, 2007, Volume: 35, Issue:4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Antifungal Agents; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Interactions; Enzyme Inhibitors; Glucuronides; Glucuronosyltransferase; Hepatocytes; Microsomes, Liver; Molecular Structure; Rats; Reverse Transcriptase Inhibitors; Tandem Mass Spectrometry; Uridine Diphosphate Glucuronic Acid; Zidovudine

2007
Bovine serum albumin decreases Km values of human UDP-glucuronosyltransferases 1A9 and 2B7 and increases Vmax values of UGT1A9.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:11

    Topics: Animals; Catechols; Cattle; Cell Membrane; Drug Interactions; Glucuronides; Glucuronosyltransferase; Humans; Hymecromone; Kinetics; Microsomes, Liver; Nitriles; Recombinant Proteins; Serum Albumin, Bovine; UDP-Glucuronosyltransferase 1A9; Uridine Diphosphate Glucuronic Acid; Zidovudine

2011
Gossypol exhibits a strong influence towards UDP-glucuronosyltransferase (UGT) 1A1, 1A9 and 2B7-mediated metabolism of xenobiotics and endogenous substances.
    Molecules (Basel, Switzerland), 2012, Apr-27, Volume: 17, Issue:5

    Topics: Enzyme Inhibitors; Estradiol; Glucuronides; Glucuronosyltransferase; Gossypol; Humans; Isoenzymes; Kinetics; Microsomes, Liver; Propofol; Substrate Specificity; Uridine Diphosphate Glucuronic Acid; Xenobiotics; Zidovudine

2012
Arginine-259 of UGT2B7 Confers UDP-Sugar Selectivity.
    Molecular pharmacology, 2020, Volume: 98, Issue:6

    Topics: Arginine; Binding Sites; Coenzymes; Crystallography, X-Ray; Glucosyltransferases; Glucuronides; Glucuronosyltransferase; Glycosides; HEK293 Cells; Humans; Hymecromone; Medicago truncatula; Molecular Dynamics Simulation; Morphine; Mutagenesis, Site-Directed; Mutation; Plant Proteins; Sequence Homology, Amino Acid; Substrate Specificity; Uridine Diphosphate Glucuronic Acid; Zidovudine

2020