Compounds > zidovudine
Page last updated: 2024-08-23

zidovudine and trovirdine

zidovudine has been researched along with trovirdine in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (75.00)18.2507
2000's1 (12.50)29.6817
2010's0 (0.00)24.3611
2020's1 (12.50)2.80

Authors

AuthorsStudies
Bell, FW; Cantrell, AS; Högberg, M; Jaskunas, SR; Johansson, NG; Jordan, CL; Kinnick, MD; Lind, P; Morin, JM; Noréen, R1
Mao, C; Sudbeck, EA; Uckun, FM; Venkatachalam, TK; Vig, R1
Mao, C; Sudbeck, EA; Uckun, FM; Venkatachalam, TK1
Maher, D; Mao, C; Pendergrass, S; Tuel-Ahlgren, L; Uckun, FM; Venkatachalam, TK; Zhu, D2
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Böttiger, D; Fleckenstein, B; Haseltine, WA; Hunsmann, G; Kaup, FJ; Li, J; Mätz-Rensing, K; Oberg, B; Stahl-Hennig, C; Uberla, K1
Aubertin, AM; Ciurea, A; Delbederi, Z; Fossey, C; Gavriliu, D; Ladurée, D; Laumond, G; Schmidt, S; Sugeac, E1

Other Studies

8 other study(ies) available for zidovudine and trovirdine

ArticleYear
Phenethylthiazolethiourea (PETT) compounds, a new class of HIV-1 reverse transcriptase inhibitors. 1. Synthesis and basic structure-activity relationship studies of PETT analogs.
    Journal of medicinal chemistry, 1995, Dec-08, Volume: 38, Issue:25

    Topics: Animals; Antiviral Agents; Cell Line; HIV-1; Humans; Isothiocyanates; Rats; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Thiazoles; Thiourea

1995
Structure-based design of N-[2-(1-piperidinylethyl)]-N'-[2-(5-bromopyridyl)]-thiourea and N-[2-(1-piperazinylethyl)]-N'-[2-(5-bromopyridyl)]-thiourea as potent non-nucleoside inhibitors of HIV-1 reverse transcriptase.
    Bioorganic & medicinal chemistry letters, 1998, Aug-18, Volume: 8, Issue:16

    Topics: Antiviral Agents; Binding Sites; Computer Simulation; Drug Design; HIV Core Protein p24; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Leukocytes, Mononuclear; Models, Molecular; Piperazines; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Thiourea; Virus Replication

1998
Rational design of N-[2-(2,5-dimethoxyphenylethyl)]-N'-[2-(5-bromopyridyl)]-thiourea (HI-236) as a potent non-nucleoside inhibitor of drug-resistant human immunodeficiency virus.
    Bioorganic & medicinal chemistry letters, 1999, Jun-07, Volume: 9, Issue:11

    Topics: Anti-HIV Agents; Delavirdine; Drug Design; Humans; Inhibitory Concentration 50; Kinetics; Models, Molecular; Nevirapine; Pyridines; Thiourea

1999
N-[2-(1-cyclohexenyl)ethyl]-N'-[2-(5-bromopyridyl)]-thiourea and N'-[2-(1-cyclohexenyl)ethyl]-N'-[2-(5-chloropyridyl)]-thiourea as potent inhibitors of multidrug-resistant human immunodeficiency virus-1.
    Bioorganic & medicinal chemistry letters, 1999, Sep-20, Volume: 9, Issue:18

    Topics: Aminopyridines; Anti-HIV Agents; Drug Resistance, Microbial; Drug Resistance, Multiple; HIV Reverse Transcriptase; HIV-1; Humans; Models, Molecular; Reverse Transcriptase Inhibitors; Thiourea

1999
N'-[2-(2-thiophene)ethyl]-N'-[2-(5-bromopyridyl)] thiourea as a potent inhibitor of NNI-resistant and multidrug-resistant human immunodeficiency virus-1.
    Bioorganic & medicinal chemistry letters, 1999, Dec-20, Volume: 9, Issue:24

    Topics: Anti-HIV Agents; Cells, Cultured; HIV-1; Humans; Microbial Sensitivity Tests; Models, Molecular; Pyridines; Reverse Transcriptase Inhibitors; Thiourea; Virus Replication

1999
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
Animal model for the therapy of acquired immunodeficiency syndrome with reverse transcriptase inhibitors.
    Proceedings of the National Academy of Sciences of the United States of America, 1995, Aug-29, Volume: 92, Issue:18

    Topics: Acquired Immunodeficiency Syndrome; Amino Acid Sequence; Animals; Antiviral Agents; Base Sequence; Cell Line; Disease Models, Animal; DNA Primers; HIV Reverse Transcriptase; HIV-1; Macaca fascicularis; Macaca mulatta; Molecular Sequence Data; Pyridines; Reverse Transcriptase Inhibitors; Simian Immunodeficiency Virus; Zidovudine

1995
Synthesis and anti-HIV activity of [d4U]-[trovirdine analogue] and [d4T]-[trovirdine analogue] heterodimers as inhibitors of HIV-1 reverse transcriptase.
    Nucleosides, nucleotides & nucleic acids, 2002, Volume: 21, Issue:8-9

    Topics: Anti-HIV Agents; Dideoxynucleosides; Dimerization; Drug Evaluation, Preclinical; HIV Reverse Transcriptase; HIV-1; Humans; Lymphocytes; Pyridines; Reverse Transcriptase Inhibitors; Stavudine; Tumor Cells, Cultured; Zidovudine

2002