zidovudine has been researched along with thymidine monophosphate in 44 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (2.27) | 18.7374 |
| 1990's | 14 (31.82) | 18.2507 |
| 2000's | 28 (63.64) | 29.6817 |
| 2010's | 1 (2.27) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bronson, JJ; Ghazzouli, I; Hitchcock, MJ; Kim, CU; Luh, BY; Martin, JC; Misco, PF | 1 |
| Busson, R; De Keukeleire, D; Dugué, L; Froeyen, M; Herdewijn, P; Heyerick, A; Munier-Lehmann, H; Pochet, S; Van Calenbergh, S; Vanheusden, V | 1 |
| Herdewijn, P; Munier-Lehmann, H; Pochet, S; Van Calenbergh, S; Van Rompaey, P; Vanheusden, V | 1 |
| Baba, M; Cheng, YC; Dutschman, GE; Hsu, CH; Hu, R; Krishnan, P; Tanaka, H; Yang, G | 1 |
| Achiwa, K; Ikeda, K; Nagao, Y | 1 |
| Eckstein, F; Grosse, F; Heidenreich, O; Kruhøffer, M | 1 |
| Agarwal, RP; Mian, AM | 1 |
| Bolognesi, DP; Broder, S; Freeman, GA; Furman, PA; Fyfe, JA; Lehrman, SN; Mitsuya, H; Rideout, JL; St Clair, MH; Weinhold, K | 1 |
| Carroll, SS; Geib, J; Kuo, LC; Olsen, DB; Shafer, JA; Stahlhut, M | 1 |
| Bridges, EG; Faraj, A; Sommadossi, JP | 1 |
| Khamnei, S; Torrence, PF | 1 |
| Kenyon, GL | 1 |
| Goody, RS; Konrad, M; Lavie, A; Reinstein, J; Schlichting, I; Vetter, IR | 1 |
| Abraham, TW; McIntee, EJ; Remmel, RP; Schinazi, RF; Wagner, CR | 1 |
| Anderson, KS; Kerr, SG | 1 |
| D'Cruz, OJ; Shih, MJ; Uckun, FM; Venkatachalam, TK; Zhu, Z | 1 |
| Chen, CL; D'Cruz, OJ; Shih, MJ; Uckun, FM; Yiv, SH | 1 |
| Chen, CL; D'Cruz, OJ; Uckun, FM; Waurzyniak, B; Yiv, SH; Zhu, Z | 1 |
| D'Cruz, OJ; Uckun, FM; Venkatachalam, TK | 2 |
| D'Cruz, OJ; Uckun, FM; Waurzyniak, B; Yiv, SH | 1 |
| Aquaro, S; Balzarini, J; Bianchi, V; De Clercq, E; Knispel, T; Meier, C; Perno, CF; Rampazzo, C | 1 |
| Matsuura, SE; Meyer, PR; Schinazi, RF; Scott, WA; So, AG | 1 |
| D'Cruz, OJ; Uckun, FM | 7 |
| D'Cruz, OJ; Erbeck, D; Uckun, FM; Waurzyniak, B | 1 |
| Domingo, E; Mas, A; Menéndez-Arias, L; Vázquez-Alvarez, BM | 1 |
| Pendergrass, S; Qazi, S; Richman, D; Uckun, FM; Venkatachalam, TK | 1 |
| Anderson, KS; Feng, JY; Furman, PA; Jeffrey, JL; Qi, CC | 1 |
| Pendergrass, S; Qazi, S; Uckun, FM; Venkatachalam, TK | 1 |
| D'Cruz, OJ; Uckun, FM; Waurzyniak, B | 1 |
| D'Cruz, O; Goodman, PA; Qazi, S; Uckun, FM; Venkatachalam, TK | 1 |
| Cases-González, CE; Menéndez-Arias, L | 1 |
| D'Cruz, OJ; Tai, HL; Uckun, FM | 1 |
| Benyumov, AO; Downs, S; Dumezb, D; Grigoriants, OO; Tibbles, HE; Uckun, FM; Vassilev, AO; Venkatachalam, TK | 1 |
| Qazi, S; Uckun, FM; Venkatachalam, TK | 1 |
| Qazi, S; Samuel, P; Uckun, FM; Venkatachalam, TK | 1 |
| Astapova, MV; Shirokova, EA; Skoblov, YS; Yanvarev, DV | 1 |
| Hsiung, CH; Kamath, VG; Lizenby, ZJ; McKee, EE | 1 |
1 review(s) available for zidovudine and thymidine monophosphate
| Article | Year |
|---|---|
Rational drug design of multifunctional phosphoramidate substituted nucleoside analogs.
Topics: Amides; Animals; Dideoxynucleotides; Dose-Response Relationship, Drug; Drug Design; Fertility Agents; Humans; Neoplasms; Nucleosides; Phosphoric Acids; Thymidine Monophosphate; Zidovudine | 2004 |
43 other study(ies) available for zidovudine and thymidine monophosphate
| Article | Year |
|---|---|
Acyclic purine phosphonate analogues as antiviral agents. Synthesis and structure-activity relationships.
Topics: Antiviral Agents; Chemical Phenomena; Chemistry; Kinetics; Organophosphonates; Purines; Retroviridae; Simplexvirus; Structure-Activity Relationship | 1990 |
3'-C-branched-chain-substituted nucleosides and nucleotides as potent inhibitors of Mycobacterium tuberculosis thymidine monophosphate kinase.
Topics: Antitubercular Agents; Azides; Enzyme Inhibitors; Humans; Kinetics; Models, Molecular; Mycobacterium tuberculosis; Nucleoside-Phosphate Kinase; Nucleosides; Nucleotides; Structure-Activity Relationship; Thymidine Monophosphate | 2003 |
Thymidine and thymidine-5'-O-monophosphate analogues as inhibitors of Mycobacterium tuberculosis thymidylate kinase.
Topics: Antitubercular Agents; Enzyme Inhibitors; Inhibitory Concentration 50; Kinetics; Mycobacterium tuberculosis; Nucleoside-Phosphate Kinase; Structure-Activity Relationship; Thymidine; Thymine Nucleotides | 2003 |
Comparison of the phosphorylation of 4'-ethynyl 2',3'-dihydro-3'-deoxythymidine with that of other anti-human immunodeficiency virus thymidine analogs.
Topics: Anti-HIV Agents; Humans; Nucleoside-Phosphate Kinase; Phosphorylation; Stavudine; Structure-Activity Relationship; Zidovudine | 2007 |
Synthesis of sialic acid-containing nucleotide sugars: CMP-sialic acid analogs.
Topics: Antiviral Agents; Cytidine Monophosphate; Dideoxynucleotides; N-Acetylneuraminic Acid; N-Acylneuraminate Cytidylyltransferase; Sialic Acids; Sialyltransferases; Thymidine Monophosphate; Thymine Nucleotides; Zidovudine | 1992 |
Inhibition of human immunodeficiency virus 1 reverse transcriptase by 3'-azidothymidine triphosphate.
Topics: Binding Sites; Catalysis; HIV-1; Kinetics; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Substrate Specificity; Thymidine Monophosphate; Thymine Nucleotides; Zidovudine | 1990 |
Thymidine and zidovudine metabolism in chronically zidovudine-exposed cells in vitro.
Topics: Cells, Cultured; Chromatography, High Pressure Liquid; Dideoxynucleotides; Humans; Phosphorylation; Thymidine; Thymidine Kinase; Thymidine Monophosphate; Thymine Nucleotides; Time Factors; Zidovudine | 1991 |
Phosphorylation of 3'-azido-3'-deoxythymidine and selective interaction of the 5'-triphosphate with human immunodeficiency virus reverse transcriptase.
Topics: Antiviral Agents; Cell Survival; HIV; Humans; Kinetics; Nucleic Acid Synthesis Inhibitors; Phosphorylation; Reverse Transcriptase Inhibitors; Thymidine; Thymidine Monophosphate; Thymine Nucleotides; Virus Replication; Zidovudine | 1986 |
Sensitivity of HIV-1 reverse transcriptase and its mutants to inhibition by azidothymidine triphosphate.
Topics: Antiviral Agents; Base Sequence; Dideoxynucleotides; Diphosphates; DNA Primers; HIV Reverse Transcriptase; HIV-1; Hydrolysis; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Substrate Specificity; Templates, Genetic; Thymidine Monophosphate; Thymine Nucleotides; Zidovudine | 1994 |
Inhibition of mammalian DNA polymerase-associated 3' to 5' exonuclease activity by 5'-monophosphates of 3'-azido-3'-deoxythymidine and 3'-amino-3'-deoxythymidine.
Topics: Animals; Cattle; Dideoxynucleotides; DNA Replication; Exonucleases; Nucleic Acid Synthesis Inhibitors; Thymidine Monophosphate; Thymine Nucleotides; Thymus Gland; Zidovudine | 1993 |
Neighboring group catalysis in the design of nucleotide prodrugs.
Topics: Animals; Brain; Catalysis; Dideoxynucleotides; Drug Design; Esterases; Glucose; Humans; Hydrolysis; Kinetics; Liver; Prodrugs; Rats; Salicylates; Salicylic Acid; Swine; Thymidine Monophosphate; Zidovudine | 1996 |
AZT monophosphate knocks thymidylate kinase for a loop.
Topics: Dideoxynucleotides; Drug Design; Models, Molecular; Nucleoside-Phosphate Kinase; Prodrugs; Protein Conformation; Thymidine Monophosphate; Thymine Nucleotides; Transcription, Genetic; Zidovudine | 1997 |
Structure of thymidylate kinase reveals the cause behind the limiting step in AZT activation.
Topics: Computer Simulation; Crystallography; Dideoxynucleotides; Models, Molecular; Molecular Conformation; Molecular Sequence Data; Motion; Nucleoside-Phosphate Kinase; Phosphorylation; Prodrugs; Saccharomyces cerevisiae; Substrate Specificity; Thymidine Monophosphate; Thymine Nucleotides; Zidovudine | 1997 |
Probing the mechanism of action and decomposition of amino acid phosphomonoester amidates of antiviral nucleoside prodrugs.
Topics: Anti-HIV Agents; Cells, Cultured; Chromatography, High Pressure Liquid; Dideoxynucleosides; HIV-1; Humans; Leukocytes, Mononuclear; Magnetic Resonance Spectroscopy; Prodrugs; Thymidine Monophosphate; Virus Replication; Zidovudine | 1997 |
Pre-steady-state kinetic characterization of wild type and 3'-azido-3'-deoxythymidine (AZT) resistant human immunodeficiency virus type 1 reverse transcriptase: implication of RNA directed DNA polymerization in the mechanism of AZT resistance.
Topics: Anti-HIV Agents; Dideoxynucleotides; Drug Resistance; HIV Reverse Transcriptase; HIV-1; Kinetics; Mutation; Reverse Transcriptase Inhibitors; Ribonuclease H; Thymidine Monophosphate; Thymine Nucleotides; Zidovudine | 1997 |
Aryl phosphate derivatives of bromo-methoxy-azidothymidine are dual-function spermicides with potent anti-human immunodeficiency virus.
Topics: Animals; Anti-HIV Agents; Cricetinae; Dideoxynucleotides; Female; Fluorescent Antibody Technique, Indirect; HIV-1; Humans; Kinetics; Male; Microscopy, Confocal; Microscopy, Electron; Sperm Motility; Sperm-Ovum Interactions; Spermatocidal Agents; Thymidine Monophosphate; Virus Replication; Zidovudine | 1998 |
Synthesis, characterization and preclinical formulation of a dual-action phenyl phosphate derivative of bromo-methoxy zidovudine (compound WHI-07) with potent anti-HIV and spermicidal activities.
Topics: Acrosome Reaction; Animals; Anti-HIV Agents; Cell Membrane; Cervix Uteri; Dideoxynucleotides; Drug Evaluation, Preclinical; Emulsions; Epithelial Cells; Female; HIV-1; Humans; Male; Rabbits; Sperm Motility; Spermatocidal Agents; Spermatozoa; Thymidine Monophosphate; Vagina; Virus Replication; Zidovudine | 1999 |
WHI-05, a novel bromo-methoxy substituted phenyl phosphate derivative of zidovudine, is a dual-action spermicide with potent anti-HIV activity.
Topics: Animals; Anti-HIV Agents; Cell Survival; Cells, Cultured; Cervix Uteri; Dideoxynucleotides; Epithelial Cells; Female; HIV Core Protein p24; HIV-1; Humans; Indicators and Reagents; Inflammation; Male; Molecular Structure; Rabbits; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Spermatocidal Agents; Spermatozoa; Thymidine Monophosphate; Tumor Cells, Cultured; Vagina; Zidovudine | 1999 |
Structural requirements for potent human spermicidal activity of dual-function aryl phosphate derivative of bromo-methoxy zidovudine (compound WHI-07).
Topics: Anti-HIV Agents; Cervix Uteri; Dideoxynucleotides; Dose-Response Relationship, Drug; Epithelial Cells; Female; Humans; Male; Molecular Structure; Sperm Motility; Spermatocidal Agents; Structure-Activity Relationship; Thymidine Monophosphate; Zidovudine | 2000 |
Evaluation of subchronic (13 weeks) and reproductive toxicity potential of intravaginal gel-microemulsion formulation of a dual-function phenyl phosphate derivative of bromo-methoxy zidovudine (compound WHI-05) in B(6)C(3)F(1) mice.
Topics: Acquired Immunodeficiency Syndrome; Administration, Intravaginal; Animals; Anti-HIV Agents; Blood Cell Count; Blood Chemical Analysis; Dideoxynucleotides; Emulsions; Female; Fertility; Gels; Male; Mice; Organ Size; Thymidine Monophosphate; Zidovudine | 2000 |
Cyclosaligenyl-2',3'-didehydro-2',3'-dideoxythymidine monophosphate: efficient intracellular delivery of d4TMP.
Topics: 5'-Nucleotidase; Anti-HIV Agents; Culture Media; Dideoxynucleotides; Half-Life; Humans; Hydrogen-Ion Concentration; Leukocytes, Mononuclear; Macrophages; Monocytes; Stavudine; Thymidine; Thymidine Kinase; Thymidine Monophosphate; Thymine Nucleotides; Time Factors; Tritium; Tumor Cells, Cultured; Zidovudine | 2000 |
Differential removal of thymidine nucleotide analogues from blocked DNA chains by human immunodeficiency virus reverse transcriptase in the presence of physiological concentrations of 2'-deoxynucleoside triphosphates.
Topics: Adenosine Triphosphate; Dideoxynucleotides; DNA Primers; HIV Reverse Transcriptase; Reverse Transcriptase Inhibitors; Stavudine; Templates, Genetic; Thymidine Monophosphate; Thymine Nucleotides; Zidovudine | 2000 |
Thymidine kinase-independent intracellular delivery of bioactive nucleotides by aryl phosphate derivatives of bromo-methoxy zidovudine (compounds WHI-05 and WHI-07) in normal human female genital tract epithelial cells and sperm.
Topics: Cervix Uteri; Chromatography, High Pressure Liquid; Dideoxynucleotides; Epithelial Cells; Female; Flow Cytometry; Genitalia, Female; Humans; Male; Nucleotides; Phosphorylation; Sperm Motility; Spermatozoa; Thymidine; Thymidine Kinase; Thymidine Monophosphate; Vagina; Zidovudine | 2001 |
Short-Term (13-week) toxicity study of 5-bromo-6-methoxy-5,6-dihydro-3'-azidothymidine-5'-(p-bromophenyl) methoxyalaninyl phosphate (WHI-07), a novel anti-HIV and contraceptive agent, in B6C3F1 mice.
Topics: Administration, Intravaginal; Animals; Anti-HIV Agents; Blood Cell Count; Body Weight; Chemistry, Clinical; Dideoxynucleotides; Dose-Response Relationship, Drug; Emulsions; Female; Gels; Longevity; Mice; Mice, Inbred Strains; Organ Size; Particle Size; Spermatocidal Agents; Thymidine Monophosphate; Toxicity Tests; Zidovudine | 2001 |
Two-year toxicity and carcinogenicity studies in B(6)C(3)F(1) mice with 5-bromo-6-methoxy-5,6-dihydro-3'-azidothymidine-5'-(p-bromophenyl) methoxyalaninyl phosphate (WHI-07), a novel anti-HIV and contraceptive agent.
Topics: Administration, Intravaginal; Animals; Anti-HIV Agents; Blood Cell Count; Blood Chemical Analysis; Body Weight; Carcinogens; Dideoxynucleotides; Emulsions; Female; Mice; Mice, Inbred Strains; Neoplasms; Organ Size; Spermatocidal Agents; Survival Analysis; Thymidine Monophosphate; Zidovudine | 2002 |
Multidrug-resistant HIV-1 reverse transcriptase: involvement of ribonucleotide-dependent phosphorolysis in cross-resistance to nucleoside analogue inhibitors.
Topics: Amino Acid Sequence; Deoxycytidine Monophosphate; Diphosphates; DNA; DNA Primers; DNA Replication; Drug Resistance, Multiple, Viral; HIV Reverse Transcriptase; Humans; Lamivudine; Molecular Sequence Data; Recombinant Proteins; Reverse Transcriptase Inhibitors; Sequence Alignment; Thymidine Monophosphate; Zalcitabine; Zidovudine | 2002 |
Stampidine is a potent inhibitor of Zidovudine- and nucleoside analog reverse transcriptase inhibitor-resistant primary clinical human immunodeficiency virus type 1 isolates with thymidine analog mutations.
Topics: Anti-HIV Agents; Dideoxynucleotides; Drug Resistance, Viral; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Nucleosides; Phenotype; Reverse Transcriptase Inhibitors; Stavudine; Structure-Activity Relationship; Thymidine; Thymidine Monophosphate; Zidovudine | 2002 |
Pre-clinical safety evaluation of novel nucleoside analogue-based dual-function microbicides (WHI-05 and WHI-07).
Topics: Animals; Anti-HIV Agents; Anti-Infective Agents; Cell Line; Contraceptive Agents, Female; Dideoxynucleotides; Drug Evaluation, Preclinical; Female; Humans; Macaca fascicularis; Mice; Nucleosides; Pregnancy; Rabbits; Thymidine Monophosphate; Zidovudine | 2002 |
Dioxolane guanosine 5'-triphosphate, an alternative substrate inhibitor of wild-type and mutant HIV-1 reverse transcriptase. Steady state and pre-steady state kinetic analyses.
Topics: Acquired Immunodeficiency Syndrome; Cytidine Triphosphate; Deoxycytidine Monophosphate; Deoxyguanine Nucleotides; Dideoxynucleotides; Dioxolanes; DNA, Viral; Drug Resistance, Viral; Guanosine; Guanosine Triphosphate; HIV Reverse Transcriptase; HIV-1; Lamivudine; Mutation; Reverse Transcriptase Inhibitors; Substrate Specificity; Thymidine Monophosphate; Thymine Nucleotides; Zidovudine | 2003 |
Contraceptive activity of a spermicidal aryl phosphate derivative of bromo-methoxy-zidovudine (compound WHI-07) in rabbits.
Topics: Administration, Intravaginal; Animals; Dideoxynucleotides; Embryo Implantation; Female; Gels; Insemination, Artificial; Male; Nonoxynol; Pregnancy; Prospective Studies; Rabbits; Semen; Spermatocidal Agents; Spermatozoa; Thymidine Monophosphate; Zidovudine | 2003 |
Contraceptive activity of a spermicidal aryl phosphate derivative of bromo-methoxy zidovudine (compound WHI-05) in rabbits.
Topics: Administration, Intravaginal; Animals; Anti-HIV Agents; Body Weight; Contraceptive Agents, Male; Dideoxynucleotides; Emulsions; Female; Fertility; Gels; Insemination, Artificial; Litter Size; Male; Pregnancy; Rabbits; Spermatocidal Agents; Survival; Thymidine Monophosphate; Zidovudine | 2003 |
In vitro activity of stampidine against primary clinical human immunodeficiency virus isolates.
Topics: Cells, Cultured; Dideoxynucleotides; Drug Resistance, Viral; Genotype; HIV; HIV Infections; HIV-1; Humans; Lamivudine; Mutation; Neutrophils; Phenotype; Reverse Transcriptase Inhibitors; Stavudine; Thymidine Monophosphate; Viral Plaque Assay; Zidovudine | 2004 |
Antiretroviral spermicide WHI-07 prevents vaginal and rectal transmission of feline immunodeficiency virus in domestic cats.
Topics: Animals; Antiviral Agents; Cats; Dideoxynucleotides; Drug Therapy, Combination; Emulsions; Feline Acquired Immunodeficiency Syndrome; Female; Gels; Immunodeficiency Virus, Feline; Male; Rectum; Retroviridae; Spermatocidal Agents; Thymidine Monophosphate; Vagina; Vanadium Compounds; Zidovudine | 2004 |
Nucleotide specificity of HIV-1 reverse transcriptases with amino acid substitutions affecting Ala-114.
Topics: Alanine; Amino Acid Substitution; Dideoxynucleosides; Dideoxynucleotides; Dinucleoside Phosphates; DNA; DNA, Viral; HIV Reverse Transcriptase; Mutagenesis, Site-Directed; Mutation; Nucleotides; Thymidine Monophosphate; Thymine Nucleotides; Zidovudine | 2005 |
Antileukemic activity and cellular metabolism of the aryl phosphate derivative of bromo-methoxy zidovudine (compound WHI-07).
Topics: Animals; Antimetabolites, Antineoplastic; Biotransformation; Carboxylic Ester Hydrolases; Cell Division; Cell Line, Tumor; Cell Survival; Cholinesterase Inhibitors; Dideoxynucleotides; Drug Resistance, Multiple; Embryo, Nonmammalian; Glutathione; Humans; Leukemia; Nucleosides; Paraoxon; Rhodamine 123; Subcellular Fractions; Tetrazolium Salts; Thiazoles; Thymidine Monophosphate; Tumor Stem Cell Assay; Zebrafish; Zidovudine | 2005 |
Anti-proliferative and anti-leukemic activity of DDE46 (compound WHI-07), a novel bromomethoxylated arylphosphate derivative of zidovudine, and related compounds. Studies using human acute lymphoblastic leukemia cells and the zebrafish model.
Topics: Animals; Antineoplastic Agents; Apoptosis; Caspase Inhibitors; Cell Proliferation; Dideoxynucleotides; Drug Screening Assays, Antitumor; Humans; Jurkat Cells; Leukemia; Magnetic Resonance Spectroscopy; Nephelometry and Turbidimetry; Prodrugs; Tetrazolium Salts; Thiazoles; Thymidine Monophosphate; Tubulin; Zebrafish; Zidovudine | 2005 |
In vitro anti-HIV potency of stampidine alone and in combination with standard anti-HIV drugs.
Topics: Anti-HIV Agents; Dideoxynucleotides; Drug Combinations; Drug Interactions; HIV-1; Humans; Lamivudine; Least-Squares Analysis; Models, Theoretical; Nelfinavir; Nevirapine; Phenotype; Stavudine; Thymidine Monophosphate; Virus Replication; Zidovudine | 2005 |
Effect of change in nucleoside structure on the activation and antiviral activity of phosphoramidate derivatives.
Topics: Amides; Animals; Anti-HIV Agents; Cell Line, Tumor; Dideoxynucleotides; Enzyme Inhibitors; Esterases; Humans; Kinetics; Lipase; Lymphocytes; Microbial Sensitivity Tests; Molecular Conformation; Peptide Hydrolases; Phenol; Phosphoric Acids; Stavudine; Stereoisomerism; Structure-Activity Relationship; Thymidine Monophosphate; Zidovudine | 2005 |
Influence of long-term stability conditions on microbicidal nucleoside prodrug (WHI-07)-loaded gel-microemulsion.
Topics: Dideoxynucleotides; Drug Stability; Emulsions; Nucleosides; Prodrugs; Temperature; Thymidine Monophosphate; Zidovudine | 2006 |
AZT 5'-Cholinephosphate as an anti-HIV agent: the study of biochemical properties and metabolic transformations using its 32P-labelled counterpart.
Topics: Anti-HIV Agents; Biological Transport; Biotransformation; Cell Extracts; Dideoxynucleotides; Enzymes; HL-60 Cells; Humans; Thymidine Monophosphate; Zidovudine | 2007 |
Evaluation of local tolerance of the antiretroviral spermicide (WHI-07)-loaded gel-microemulsion in the porcine female reproductive tract.
Topics: Administration, Intravaginal; Animals; Anti-Retroviral Agents; Benzalkonium Compounds; Body Fluids; Cytokines; Dideoxynucleotides; Emulsions; Female; Flow Cytometry; Genitalia, Female; Irritants; Leukocytes; Mucous Membrane; Spermatocidal Agents; Swine; Thymidine Monophosphate; Toxicity Tests; Vaginal Creams, Foams, and Jellies; Vaginal Douching; Zidovudine | 2008 |
Preclinical evaluation of a dual-acting microbicidal prodrug WHI-07 in combination with vanadocene dithiocarbamate in the female reproductive tract of rabbit, pig, and cat.
Topics: Animals; Anti-HIV Agents; Apoptosis; Cats; Cytokines; Dideoxynucleotides; Emulsions; Female; Flow Cytometry; Gels; Genitalia, Female; Mucous Membrane; Rabbits; Spermatocidal Agents; Swine; Thymidine Monophosphate; Vagina; Vanadium Compounds; Zidovudine | 2007 |
Heart mitochondrial TTP synthesis and the compartmentalization of TMP.
Topics: Animals; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Creatine Kinase; Cytosol; Electron Transport; Female; Membrane Potential, Mitochondrial; Mitochondria, Heart; Myocardium; Oligomycins; Phosphocreatine; Phosphorylation; Potassium Cyanide; Rats; Rats, Sprague-Dawley; Thymidine; Thymidine Kinase; Thymidine Monophosphate; Thymine Nucleotides; Zidovudine | 2015 |