zidovudine has been researched along with stavudine in 607 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (2.14) | 18.7374 |
| 1990's | 166 (27.35) | 18.2507 |
| 2000's | 284 (46.79) | 29.6817 |
| 2010's | 137 (22.57) | 24.3611 |
| 2020's | 7 (1.15) | 2.80 |
| Authors | Studies |
|---|---|
| Horwitz, JP; Kessel, D; Meltsner, BR; Palomino, E | 1 |
| Augustyns, K; Balzarini, J; Blaton, N; De Clercq, E; De Ranter, C; Everaert, D; Janssen, G; Jie, L; Peeters, O; Van Aerschot, A | 1 |
| August, EM; Brankovan, V; Ghazzouli, I; Hitchcock, MJ; Lin, TS; Mansuri, MM; Prusoff, WH; Sommadossi, JP; Starrett, JE; Sterzycki, RZ | 1 |
| Ahn, MK; Chu, CK; Gu, ZP; Schinazi, RF; Ullas, GV | 1 |
| Bordner, J; Broder, S; Dalgleish, AG; Greengrass, CW; Hamilton, F; Hoople, DW; Marriott, MS; Mitsuya, H; Street, SD | 1 |
| Baba, M; Balzarini, J; Broder, S; De Clercq, E; Herdewijn, P; Pauwels, R; Vanderhaeghe, H | 1 |
| Chen, MS; Gao, YS; Ghazzouli, I; Lin, TS; McLaren, C; Prusoff, WH | 1 |
| Antonenko, SV; Chentsova, NP; Kukhar, VP; Luik, AI; Poda, GI; Tetko, IV | 1 |
| Henin, Y; Lemaitre, M; Pierlot, C; Sergheraert, C; Tartar, A | 1 |
| Balzarini, J; Cahard, D; De Clercq, E; McGuigan, C; Sheeka, HM | 1 |
| Balzarini, J; De Clercq, E; Lorey, M; Meier, C | 1 |
| Chen, CL; Jan, ST; Tai, HL; Uckun, FM; Venkatachalam, TK; Vig, R | 1 |
| Balzarini, J; De Clercq, E; Knispel, T; Meier, C | 1 |
| Balzarini, J; De Clercq, E; Knispel, T; Marquez, VE; Meier, C; Siddiqui, MA | 1 |
| Cha, SH; Endou, H; Kanai, Y; Kimura, M; Sekine, T; Tsuda, M; Wada, S | 1 |
| Bader, JP; Cragg, GM; Newman, DJ; Yang, SS | 1 |
| Beabealashvilli, RS; Fedyuk, NV; Goryunova, LY; Khandazhinskaya, AL; Kukhanova, MK; Pokrovsky, AG; Pronyaeva, TR; Shirokova, EA; Skoblov, YS; Victorova, LS; Zolin, VV | 1 |
| Balzarini, J; Barchi, JJ; Boyer, PL; Choi, Y; Comin, MJ; George, C; Hughes, SH; Jacobson, KA; Kim, HS; Marquez, VE; Mitsuya, H | 1 |
| Anderson, KS; Chu, CK; Mathew, JS; Ray, AS; Schinazi, RF; Shi, J | 1 |
| Bocharov, EV; Fedyuk, NV; Ivanov, AV; Jasko, MV; Khandazhinskaya, AL; Kukhanova, MK; Mitkevich, VA; Pokrovsky, AG; Pronyaeva, TR; Shirokova, EA; Skoblov, YS; Yanvarev, DV | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Alvarez, K; Balzarini, J; Barral, K; Canard, B; Neyts, J; Priet, S; Sire, J | 1 |
| Baba, M; De Clercq, E; Shi, M; Takao, S; Wang, X | 1 |
| Asif, G; Chu, CK; Delinsky, D; Hurwitz, SJ; McClure, HM; Narayanasamy, J; Obikhod, A; Schinazi, RF | 1 |
| Boojamra, CG; Cihlar, T; Douglas, J; Grant, D; Hui, H; Kim, CU; Laflamme, G; Mackman, RL; Parrish, J; Prasad, V; Stoycheva, AD; Swaminathan, S; Wang, K; Zhang, L | 1 |
| Baba, M; Cheng, YC; Dutschman, GE; Grill, SP; Hu, R; Lam, W; Paintsil, E; Tanaka, H | 1 |
| Andricopulo, AD; Moda, TL; Montanari, CA | 1 |
| Ainsworth, J; Booth, C; Bradshaw, D; Geretti, AM; Malik, S; Pattery, T; Van Houtte, M; Waters, A | 1 |
| Anderson, DJ; Gottlieb, GS; Preston, BD; Pyrak, CL; Smith, RA | 1 |
| Beadle, JR; Bradley, M; Farasati, NA; Hostetler, KY; Huang, Y; Meier, C; Randhawa, P; Sauerbrei, A; Zemlicka, J | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Haas, RH; Naviaux, RK; Saitoh, A; Salva, NG; Spector, SA; Wong, JK | 1 |
| LaClair, DD; Lynx, MD; McKee, EE | 1 |
| Chou, KC; González-Díaz, H; Martinez de la Vega, O; Prado-Prado, FJ; Ubeira, FM; Uriarte, E | 1 |
| Bachmann, MH; Fessel, WJ; Kagan, RM; Mitsuya, Y; Shafer, RW; Shahriar, R; Varghese, V | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Amblard, F; Bassit, L; Bondada, L; Coats, SJ; Detorio, M; Grier, J; Hernandez-Santiago, BI; Koontz, D; Mellors, JW; Rapp, KL; Schinazi, RF; Sluis-Cremer, N | 1 |
| Baba, M; Cheng, YC; Dutschman, GE; Grill, SP; Hamasaki, T; Paintsil, E; Tanaka, H; Wang, CJ; Wang, J; Yang, G | 1 |
| Behrens, GM; Das, AM; Lücke, T; Schmidt, RE; Stankov, MV | 2 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Campillo, NE; Guerra, A; Páez, JA | 1 |
| Li, Y; Liotta, DC; Liu, L; Lutz, S; Soni, PB; Zhang, X | 1 |
| Almond, MR; Buckheit, RW; Hartman, T; Keilholz, L; Lampert, BM; Lanier, ER; Mankowski, MK; Osterling, MC; Painter, GR; Ptak, RG | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Glen, RC; Lowe, R; Mitchell, JB | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Balzarini, J; Bourdin, C; Chamberlain, S; Derudas, M; Hamon, N; Hinsinger, K; Introini, A; Kandil, S; Kolykhalov, A; Madela, K; Margolis, L; McGuigan, C; Meneghesso, S; Pertusati, F; Serpi, M; Slusarczyk, M; Vanpouille, C; Vernachio, J | 1 |
| Gangadhara, KL; Herdewijn, P; Lescrinier, E; Pannecouque, C | 1 |
| Arumugam, SR; Badri, KR; He, JJ; Visalli, RJ; Zhang, X; Zhao, H; Ziobrowski, H | 1 |
| Balzarini, J; Meier, C; Schols, D; Weinschenk, L | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Jones, LH; Nadanaciva, S; Rana, P; Will, Y | 1 |
| Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
| Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M | 1 |
| Du, DL; Grieshaber, CK; Murphy, MJ; Volpe, DA | 1 |
| Arzumanov, AA; Diatkina, NB; Eremin, OG; Ias'ko, MV; Kraevskiĭ, AA; Martynov, BI; Semchenko, FM | 1 |
| el-Torgoman, AM; Kjaersgaard, U; Nielsen, C; Pedersen, EB | 1 |
| Burger, RA; Hitchcock, M; Morrey, JD; Okleberry, KM; Sidwell, RW; Warren, RP | 1 |
| Cooper, DA; Danner, SA; Lange, JM | 1 |
| Keilbaugh, SA; Prusoff, WH; Simpson, MV | 1 |
| Hitchcock, MJ; Sommadossi, JP; Zhu, Z | 1 |
| Bregman, CL; Buroker, RA; Desiderio, JV; Ghazzouli, I; Hitchcock, MJ; Mansuri, MM; Martin, JC; Starrett, JE; Sterzycki, RZ | 1 |
| Gerber, MA; Lampertico, P; Malter, JS | 1 |
| Broder, S; Kageyama, S; Mitsuya, H; Yarchoan, R | 1 |
| Chen, CH; Cheng, YC; Vazquez-Padua, M | 1 |
| Lin, TS; Prusoff, WH; Schinazi, RF | 1 |
| Nakashima, H; Tochikura, TS; Yamamoto, N | 1 |
| Baba, M; De Clercq, E; Desmyter, J; Nakashima, H; Pauwels, R; Schols, D | 1 |
| Broder, S; Cooney, DA; Hao, Z; Hartman, NR; Johns, DG; Mitsuya, H; Perno, CF; Webb, DS; Yarchoan, R | 1 |
| Balzarini, J; De Clercq, E; Herdewijn, P | 1 |
| Hiraoka, W; Kuwabara, M; Matsuda, A; Sato, F; Tanabe, K; Ueda, T | 1 |
| Baba, M; De Clercq, E; Desmyter, J; Herdewijn, P; Pauwels, R; Vandeputte, M | 1 |
| Hamamoto, Y; Matsuda, A; Matsui, T; Nakashima, H; Ueda, T; Yamamoto, N | 1 |
| Portegies, P | 1 |
| Mitsuya, H | 1 |
| Neuzil, KM | 1 |
| Lacey, SF; Larder, BA | 1 |
| López-Galíndez, C; Nájera, I; Nájera, R; Olivares, I; Peinado, MA; Perucho, M; Richman, DD; Rojas, JM | 1 |
| Cheng, YC; Liu, SH; Skalski, V | 1 |
| Stretcher, BN | 1 |
| Church, JA; Dunkle, LM; Federici, ME; Goldsmith, JC; Harris, AT; Kaul, S; Kline, MW; Loewen, DF; Schultze, ME; Woods, L | 1 |
| Gunnarsson, G; Hammer, SM | 1 |
| Hoernle, EH; Reid, TE | 1 |
| Hansen, JE; Mathiesen, LR; Nielsen, C; Nielsen, JO; Sørensen, AM | 1 |
| Duriez, P; Fruchart, JC; Kusnierz, JP; Lestavel-Delattre, S; Martin-Nizard, F; Parmentier, B; Pierlot, C; Sergheraert, C; Sqalli-Houssaini, H; Tartar, A | 1 |
| Dudley, MN | 1 |
| Bawdon, RE; Kaul, S; Sobhi, S | 1 |
| Bechtold, CM; Federici, ME; Khan, NC; Li, H; Lin, PF; Patick, AK; Revie, DR; Rose, RE; Samanta, H; Trimble, J | 1 |
| Lüthy, R | 1 |
| Gao, Q; Gu, Z; Nagai, K; Parniak, MA; Salomon, H; Wainberg, MA | 1 |
| Balzarini, J | 1 |
| Volberding, PD | 1 |
| Magnuson, T; Mourton, T; Toltzis, P | 1 |
| Katz, MH | 1 |
| Cretton, EM; Hitchcock, MJ; Kaul, S; Kidd, LB; McClure, HM; Sommadossi, JP; Zhou, Z | 1 |
| Cooper, DA; Emery, S | 1 |
| Besley, D; Graham, NM; Jacobson, LP; Muñoz, A; Murphy, R; Park, LP; Zucconi, S | 1 |
| Chou, TC; Polsky, B; Scarborough, A; Zhu, QY | 1 |
| Pollard, RB | 1 |
| Allen, SJ; Chen, MS; Cherrington, JM; Fuller, MD; Kunder, SC; Lesnikowski, Z; Mulato, AS; Schinazi, RF; Sommadossi, JP; Ussery, MA | 1 |
| Nosbisch, C; Odinecs, A; Unadkat, JD | 1 |
| Back, D; Barry, M; Hoggard, P; Khoo, S | 1 |
| Ho, DD | 1 |
| Chikami, GK; Piazza-Hepp, TD; Styrt, BA | 1 |
| Lane, HC; Masur, H; Spooner, KM | 1 |
| Arezzo, JC; Bregman, CL; Comereski, CR; Davidson, TJ; Durham, SK; Frantz, JD; Kaul, S; Knupp, CA; Warner, WA; Wasserman, AJ | 1 |
| Hasegawa, T; Juni, K; Kawaguchi, T; Saneyoshi, M | 1 |
| Baba, M; Hashimoto, KI; Okamoto, M; Shigeta, S; Tsunoda, R | 1 |
| Aguirrebengoa, K; Mallolas, J; Torres Tortosa, M; Uriz, J | 1 |
| Cross, A; Dellamonica, P; Dunkle, L; Gathe, J; Jemsek, JG; Mellors, JW; Murphy, R; Pavia, AT; Spruance, SL; Stool, E | 1 |
| Cui, L; Locatelli, L; Sommadossi, JP; Xie, MY | 1 |
| Hirschel, B; Rutschmann, O | 1 |
| Gates, GA; Longstreth, WT; Marra, CM; Rees, TS; Syapin, CL; Wechkin, HA | 1 |
| Heins, JR | 1 |
| al-Mulla, W; Church, D; Gill, MJ | 1 |
| Brizzi, M; Ceccherini-Nelli, L; Forastieri, G; Iuliano, R; Mazzotta, F; Mecocci, L | 1 |
| Back, DJ; Barry, MG; Hoggard, PG; Kewn, S; Khoo, SH | 1 |
| Barbhaiya, RH; Brundage, RC; Sawchuk, RJ; Yang, Z | 1 |
| Collins, DO; Sakamoto, A | 1 |
| Roca, B; Simón, E | 1 |
| Balfour, HH; Chodakewitz, JA; Currier, JS; Demeter, LM; Deyton, LR; Eron, JJ; Feinberg, JE; Fischl, MA; Grimes, JM; Hammer, SM; Hughes, MD; Squires, KE | 1 |
| Chiang, Y; Drake, RR; Govindarajan, R; Hume, SD; Krisa, S; McMasters, R; Munshi, NC; Rechtin, TM; Saylors, RL | 1 |
| Back, DJ; Barry, MG; Hoggard, PG; Kewn, S; Veal, GJ | 1 |
| Feingold, A; Meislich, D; Rudy, B; Rutstein, RM; Word, B | 1 |
| Cottalorda, J; Lefbvre, JC; Mariani, R; Monpoux, F; Sirvent, N | 1 |
| Arranz Caso, JA | 1 |
| Culnane, M; Gwynne, M; Hutcheon, N; Kline, MW; Lindsey, JC; McKinney, RE; Mitchell, WG; Nichols, S; Van Dyke, RB; Yogev, R | 1 |
| Back, DJ; Barry, MG; Hoggard, PG; Manion, V | 1 |
| Barton, S; Blaxhult, A; Clotet, B; Goebel, FD; Hirschel, B; Katlama, C; Lundgren, JD; Pedersen, C; Phillips, AN; Vella, S | 1 |
| Conway, B; Hogg, RS; Montaner, JS; O'Shaughnessy, MV; Rhone, SA; Schechter, MT; Sherlock, C; Yip, B | 1 |
| Chelstrom, LM; Dibirdik, I; Irvin, JD; Langlie, MC; Myers, DE; Tuel-Ahlgren, L; Uckun, FM | 1 |
| Ortega-Larrocea, G; Rutzen, AR; Tanguilig, GG | 1 |
| Blanchard, G; Blum, L; Calvo, F; Danne, O; Lebbé, C; Morel, P; Pellet, C; Vérola, O | 1 |
| Bloor, S; de Béthune, MP; Gröschel, B; Harrigan, PR; Hertogs, K; Kemp, SD; Larder, BA; Miller, V; Pauwels, R; Staszewski, S; Stürmer, M | 1 |
| Aboulker, JP; Batisse, D; Belec, L; Castiel, P; Gilquin, J; Gonzalez-Canali, G; Jayle, D; Karmochkine, M; Kazatchkine, MD; Piketty, C; Si Mohamed, A; Weiss, L | 1 |
| Batisse, D; Belec, L; Karmochkine, M; Kazatchkine, MD; Piketty, C; Si Mohamed, A | 1 |
| Kaiser, R; Rockstroh, JK; Sauerbruch, T; Spengler, U; Theisen, A | 1 |
| Bridges, EG; Cheng, YC; Dutschman, GE; Gullen, E; Guo, X; Kukhanova, M; Liu, SH | 1 |
| Baldeweg, T; Catalan, J; Gazzard, BG | 1 |
| Bellman, PC | 1 |
| Brew, BJ | 1 |
| Fuchs, D; Gisslén, M; Hagberg, L; Svennerholm, B | 1 |
| de Jong, JJ; de Wolf, F; Foudraine, NA; Jan Weverling, G; Jurriaans, S; Keet, IP; Lange, JM; Maas, J; Roos, MT; van Benthem, BH; Vandermeulen, K | 1 |
| Bachmeyer, C; Blum, L | 1 |
| Tashima, KT | 1 |
| Kempf-Durepaire, G; Krantz, V; Lang, JM; Nicolle, M; Partisani, M; Rey, D; Schmitt, AC; Schmitt, MP | 1 |
| Segal, MB; Thomas, SA | 1 |
| Saag, MS; Schooley, RT | 1 |
| Aberg, JA; Jacobson, MA; Yajko, DM | 1 |
| Chan, KC; Ho, TT; Lee, SS; Wong, KH | 1 |
| Gitterman, SR; Pratt, RD; Struble, KA | 1 |
| Mayers, DL | 1 |
| Moyle, GJ; Sadler, M | 1 |
| Baron, F; Daniel, C; Moutschen, M | 1 |
| Gao, WY; Johns, DG; Mitsuya, H; Tanaka, M | 1 |
| Smith, L | 1 |
| Chaisson, RE; Gallant, JE; Keruly, JC; Moore, RD | 1 |
| Brunet, C; Chambost, H; Giraud, P; Michel, G; Perrimond, H; Tamalet, C; Thuret, I | 1 |
| de Wolf, F; Foudraine, NA; Hoetelmans, RM; Keet, IP; Lange, JM; Maas, JJ; Portegies, P; van Benthem, BH | 1 |
| Back, DJ; Barry, MG; Henry-Mowatt, JS; Hoggard, PG; Kewn, S; Sales, SD; Veal, GJ | 1 |
| Chêne, G; Cotte, L; Debord, T; Decazes, JM; Ferchal, F; Journot, V; Madelaine, I; Molina, JM; Pellegrin, I; Rancinan, C; Sombardier, MN | 1 |
| Bassett, R; Bell, D; Eron, JJ; Fife, K; Fischl, MA; Johnson, VA; Kuritzkes, DR; Maenza, J; Marschner, I; Murphy, RL; Pettinelli, C; Rosandich, ME; Sommadossi, JP; Wood, K | 1 |
| Goulder, PJ; Jones, NG; Kalams, SA; Ogg, GS; Shea, AK; Trocha, AK; Walker, BD | 1 |
| Hogg, RS; Jahnke, N; Montaner, JS; O'Shaughnessy, M; Yip, B | 1 |
| Aubertin, AM; Ayi, AI; Cardona, VM; Guedj, R | 1 |
| Balzarini, J; Cahard, D; De Clercq, E; McGuigan, C; Naesens, L; Pathirana, R; Saboulard, D; Salgado, A; Velazquez, S | 1 |
| Medina, DJ; Strair, RK; Tung, PP | 1 |
| Aleman, S; Loré, K; Sönnerborg, A; Visco-Comandini, U | 1 |
| Ahrens, P; Funk, MB; Hoffmann, F; Kornhuber, B; Kreuz, W; Linde, R; Notheis, G; Schuster, T; Wintergerst, U | 1 |
| Bruno, F; Gastaut, JA; Lang, JM; Partisani, M; Poizot-Martin, I; Rouviere, O; Saint-Marc, T; Touraine, JL | 1 |
| Denayrolles, M; Fleury, H; Izopet, J; Massip, P; Montes, B; Pellegrin, I; Pellegrin, JL; Puel, J; Reynes, J; Segondy, M | 1 |
| Adorni, F; Citterio, P; d'Arminio-Monforte, A; Galazzi, M; Galli, M; Gianotto, M; Grassini, A; Kurtagic, S; La Seta-Catamancio, S; Milazzo, L; Moroni, M; Rusconi, S; Testa, L | 1 |
| Bicart-See, A; Bonnet, E; Izopet, J; Marchou, B; Massip, P; Pasquier, C; Puel, J; Sandres, K | 1 |
| Aquaro, S; Balzarini, J; De Clercq, E; Knispel, T; Meier, C; Naesens, L; Perno, C | 1 |
| Temesgen, Z; Wright, AJ | 1 |
| Arlotto, C; Bernard, A; Bernard-Pomier, G; Breittmayer, JP; Dellamonica, P; Pradier, C; Pugliese, P; Roger, PM | 1 |
| Arrizabalaga, J; Clotet, BG; Cruceta, A; Dalmau, D; Gallart, T; García, F; Gatell, JM; Gomez-Sirvent, JL; Grau, I; Knobel, H; Miró, JM; O'Brien, WA; Podzamczer, D; Pumarola, T; Romeu, J; Sambeat, MA | 1 |
| Bentwich, Z; Berrebi, A; Klepfish, A; Schattner, A; Shtalrid, M; Shvidel, L | 1 |
| Balzarini, J; Camarasa, MJ; Chamorro, C; De Clercq, E; Jimeno, ML; Tuñón, V; Velázquez, S | 1 |
| Flepp, M; Jost, J; Ledergerber, B; Opravil, M; Paris, D; Ruef, C; Weber, R; Zimmerli, S | 1 |
| Enting, RH; Foudraine, NA; Jurriaans, S; Lange, JM; Portegies, P; van der Poll, T; Weverling, GJ | 1 |
| Borkowsky, W; Fiscus, S; Jimenez, E; Lee, S; McIntosh, K; Mofenson, L; Nachman, SA; Pelton, S; Pitt, J; Rathore, M; Smith, ME; Stanley, K; Wells, B; Wiznia, A; Yogev, R | 1 |
| Gendelman, HE; Lanier, ER; Limoges, J; McClernon, DR; Persidsky, Y; Poluektova, L; Rasmussen, J; Ratanasuwan, W; Zelivyanskaya, M | 1 |
| Alexander, CS; Harrigan, PR; Mo, T; Montaner, JS; Raboud, JM; Rae, S; Rouleau, D; Zala, C | 1 |
| Coakley, EP; Gillis, JM; Hammer, SM | 1 |
| Andreotti, M; Bricalli, D; Clerici, M; Dally, LG; Di Fabio, S; Ferrante, P; Pirillo, M; Principi, N; Saresella, M; Vanzulli, A; Vella, S; Vigano, A | 1 |
| Clumeck, N | 1 |
| Bart, PA; Chapuis, A; De Boer, RJ; Fox, CH; Halkic, N; Hoover, S; Lange, JM; Lazzarin, A; Miller, V; Notermans, DW; Pantaleo, G; Perrin, L; Rizzardi, GP; Staszewski, S; Tambussi, G | 1 |
| Aoki, M; Genka, I; Kikuchi, Y; Oka, S; Tachikawa, N; Teruya, K; Yamaguchi, M; Yamamoto, Y; Yasuoka, A; Yasuoka, C | 1 |
| Agou, F; Biondi, R; Deville-Bonne, D; Guerreiro, C; Sarfati, R; Schneider, B; Veron, M | 1 |
| Allende, MC; Belloso, WH; Benetucci, JA; Cahn, PE; Davey, RT; Emery, S; Lane, HC; Lasala, MC; Law, MG; Lopardo, G; Losso, MH; Nelson, E; Salomon, H; Saracco, M | 1 |
| Martínez, E; Moreno, S | 1 |
| Beylot, J; Dabis, F; Dequae-Merchadou, L; Marimoutou, C; Mercié, P; Morlat, P; Neau, D; Pellegrin, I | 1 |
| Alvarez, A; Barreiro, P; Briones, C; de Mendoza, C; Gallego, O; González-Lahoz, J; Soriano, V | 1 |
| Anwar, D; Geené, D; Goehring, C; Hirschel, B; Saaïdia, A; Sudre, P | 1 |
| Boschini, A; Calista, D | 1 |
| Fife, KH; Fox, L; Friedland, GH; Havlir, DV; Kessler, H; Pollard, RB; Richman, DD; Smeaton, L; Sommadossi, JP; Tierney, C | 1 |
| Carr, A; Chuah, J; Cooper, DA; Emery, S; French, M; Hoy, J; Hudson, J; Law, M; Sayer, D | 1 |
| Burger, DM; Hoetelmans, RM; Jurriaans, S; Lange, JM; Portegies, P; Prins, JM; Sommadossi, JP; Turner-Foisy, ML; van Praag, RM; Weverling, GJ; Zhou, XJ | 1 |
| Boretto, J; Canard, B; Deville-Bonne, D; Guerreiro, C; Janin, J; Meyer, P; Sarfati, S; Schneider, B; Véron, M | 1 |
| Kong, F; Ning, J | 1 |
| James, IR; John, M; Mallal, SA; McKinnon, EJ; Moore, CB | 1 |
| Agut, H; Angleraud, F; Bonmarchand, M; Brun-Vezinet, F; Calvez, V; Coutellier, A; Delaugerre, C; Descamps, D; Izopet, J; Katlama, C; Matheron, S; Mouroux, M; Valantin, MA; Yvon-Groussin, A | 1 |
| Ahmed, PS; Bedard, J; Bowlin, TL; Chambers, P; Clarke, J; Kelly, LA; Rando, RF; Taylor, DL; Tyms, AS; Wood, LJ | 1 |
| Bryson, YJ; Deville, J; Equils, O; Garratty, E; Krogstad, P; Nielsen, K; Plaeger, S; Sim, MS; Tapia, M; Wei, LS | 1 |
| Acosta, EP; Bassett, RL; Bell, D; Eron, JJ; Fife, K; Johnson, VA; Kuritzkes, DR; Marschner, IC; Martinez, A; Murphy, RL; Pettinelli, CB; Sommadossi, JP; Wood, K | 1 |
| Clark, R; Cohen, C; Cooley, T; Grosso, R; Gulick, R; Marlowe, SI; Mauney, J; Mulanovich, V; Santana, J; Schoellkopf, N; Squires, KE; Stevens, M; Tebas, P; Uffelman, K; Wright, D; Yangco, B | 1 |
| Bellos, N; Eron, JJ; Esinhart, J; Grosso, R; Jemsek, J; Murphy, RL; Parenti, DM; Peterson, D; Pottage, J; Rashbaum, BC; Schoellkopf, N; Sepulveda, G; Stevens, M; Swindells, S | 1 |
| Badia, X; Benavides, A; Coma, A; López Lavid, C; Pinto, JL | 1 |
| Bower, M; Gazzard, BG; Mandalia, S; Matthews, GV; Moyle, GJ; Nelson, M | 1 |
| Belec, L; Costagliola, D; Kazatchkine, MD; Ledeine, JM; Mohammed, AS; Troccaz, M; Van, PN | 1 |
| Aquaro, S; Balzarini, J; Bianchi, V; De Clercq, E; Knispel, T; Meier, C; Perno, CF; Rampazzo, C | 1 |
| Albright, AV; Erickson-Viitanen, S; Frank, I; González-Scarano, F; O'Connor, M; Rayner, MM | 1 |
| Alonso, MM; Arrizabalaga, J; Clotet, B; Cruceta, A; Dalmau, D; Ferrer, E; Frances, A; Gallart, T; García, F; Gatell, JM; Gomez-Sirvent, JL; Knobel, H; Miró, JM; O'Brien, WA; Pumarola, T; Romeu, J; Ruiz, I; Segura, F; Vidal, F | 1 |
| Matsuura, SE; Meyer, PR; Schinazi, RF; Scott, WA; So, AG | 1 |
| de Ronde, A; de Rooij, E; Goudsmit, J; Lange, J; van Dooren, M; van Gemen, B | 1 |
| Fiore, TC; Tashima, KT | 1 |
| Gonzalez-Muñoz, M; Madrigal, P; Martinez-Rodriguez, S; Polo, R; Verdejo, J | 1 |
| Darque, A; Moore, JD; Sommadossi, JP; Valette, G; Zhou, XJ | 1 |
| Boretto, J; Canard, B; Guerreiro, C; Longhi, S; Mulard, L; Navarro, JM; Sarfati, S; Selmi, B; Sire, J | 1 |
| Busch, M; Hecht, FM; Kahn, J; Levy, JA; Martinez-Marino, B; Ong, JC; Stranford, SA | 1 |
| Fleury, H; Garrigue, I; Izopet, J; Massip, P; Montes, B; Pellegrin, I; Pellegrin, JL; Puel, J; Reynes, J; Segondy, M | 1 |
| Brown, T; Feingold, AR; Meislich, D; Rudy, BJ; Rutstein, RM | 1 |
| Back, DJ; Carey, P; Hart, CA; Hoggard, PG; Khoo, SH; Lloyd, J; Maher, BA; Phiboonbanakit, D; Sales, SD; Wilkins, E | 1 |
| Becker, SL; Fusco, GP; Fusco, JS; Graham, NM; Hansen, NI; Igboko, EF; Raffanti, SR; Slatko, GH | 1 |
| Back, DJ; Hart, CA; Hoggard, PG; Kewn, S; Khoo, SH; Sales, SD; Sunderland, D | 1 |
| Arendt, G; Hefter, H; Theisen, A; von Giesen, HJ | 1 |
| Chaisson, RE; Keruly, JC; Moore, RD | 1 |
| Copeland, WC; Lim, SE | 1 |
| Carr, A; Mallon, P; Morey, A; Thorburn, DR; Williams, D | 1 |
| Gilden, D | 2 |
| Poscher, M | 1 |
| Conant, M | 1 |
| Torres, G | 1 |
| Japour, AJ | 1 |
| Smart, T | 3 |
| Cheng, B | 1 |
| Smart, T; Torres, G | 1 |
| Elperin, A; Sax, P | 1 |
| Falkenberg, J; Gilden, D; Torres, G | 1 |
| Zuger, A | 1 |
| Baker, R | 1 |
| Wool, M | 1 |
| Bowersox, J | 1 |
| Cadman, J | 1 |
| Maenza, JR | 1 |
| Amaro, J; Bienvenu, L; Burel, F; Hofman, P; Hofman, V; Itchaï, C | 1 |
| Gazzard, BG; Gilleece, Y; Hertogs, K; Pozniak, AL; Torti, C | 1 |
| Bonot, P; Caumont, A; Fleury, H; Garrigue, I; Merel, P; Pellegrin, I; Pellegrin, JL; Schrive, MH | 1 |
| Burlina, A; D'Elia, R; De Romeo, A; De Rossi, A; Giacomet, V; Giaquinto, C; Rampon, O; Ruga, E; Sturkenboom, M | 1 |
| Danner, SA; de Boer, RJ; Goudsmit, J; Huismans, R; Jebbink, MF; Lukashov, VV | 1 |
| Beckmann, RA; Bogner, JR; Goebel, FD; Michl, G; Salzberger, B; Vielhauer, V; Wille, L | 1 |
| Hughes, M; Katzenstein, DA; Liou, SH; Machekano, RA; Shafer, RW; Shulman, NS; Winters, MA; Zolopa, AR | 1 |
| Angelini, E; Chêne, G; Clavel, F; Ferchal, F; Maillard, A; Molina, JM; Picard, V; Race, E | 1 |
| Becker, S; Fisher, R; Graham, N; Henry, K; Hernandez, J; Hirani, A; Liao, Q; Raffanti, S; Ross, L; Scarsella, A; St Clair, M | 1 |
| Cain, D; Clarke, JR; Erlwein, O; Frater, AJ; Grigg, AR; Hill, CL; McClure, MO; Patton, G; Rosenblum, LL | 1 |
| Miller, MD; Naeger, LK | 1 |
| Aubertin, AM; Benzaria, S; Ciurea, A; Delbederi, Z; Fossey, C; Gavriliu, D; Kirn, A; Ladurée, D; Lelong, B | 1 |
| Antinori, A; Bruno, R; Bugarini, R; Chigiotti, S; Chirianni, A; De Luca, A; De Stefano, C; Gritti, F; Monforte, Ade A; Moroni, M; Mussini, C; Perrella, O; Pezzotti, P; Piazza, M; Pizzigallo, E; Tirelli, U; Vigevani, GM | 1 |
| Duan, C; Kuritzkes, DR; McHenry, CS; Petropoulos, CJ; Poticha, D; Stoeckli, TC; Whitcomb, JM | 1 |
| Bernasconi, E; Boggian, K; Boubaker, K; Chave, JP; Egger, M; Flepp, M; Francioli, P; Furrer, H; Haensel, A; Hirschel, B; Opravil, M; Rickenbach, M; Sudre, P; Telenti, A | 1 |
| Blumoff, K; Garcia-Lerma, JG; Heneine, W; Nidtha, S; Weinstock, H | 1 |
| Chadapaud, S; Hittinger, G; Lafeuillade, A; Poggi, C | 1 |
| Abbadessa, V; Andreoni, M; D'Ettorre, G; Dalle, NE; Gallo, I; Mancino, G; Narciso, P; Nicastri, E; Parisi, SG; Sarmati, L; Traina, C; Vullo, V | 1 |
| Anastos, K; Burke, J; Cohen, MH; Cook, JA; Grey, D; Kirstein, L; Palacio, H; Richardson, J; Wilson, TE; Young, M | 1 |
| Agut, H; Bonmarchand, M; Brun-Vezinet, F; Calvez, V; Costagliola, D; Coutellier, A; Delaugerre, C; Descamps, D; Izopet, J; Katlama, C; Massip, P; Matheron, S; Mouroux, M; Valantin, MA; Yvon, A | 1 |
| Craig, K | 1 |
| Emery, VC; Lock, MJ; Teo, J; Thorley, N | 1 |
| Agrofoglio, LA; Cahours, X; Dessans, H; Morin, P | 1 |
| Delaporte, E; Malonga-Mouellet, G; Mansaray, H; Mavoungou, R; Mistoul, I; Peeters, M; Vergne, L | 1 |
| Jiricny, J | 1 |
| Cheng, YC; Chou, KM | 1 |
| Jaccard, R; Jenni, R; Opravil, M; Speich, R | 1 |
| Bettendorf, D; Bucy, RP; Chan, E; Evans, T; Gonzalez, CJ; Landay, AL; Phair, JP; Schmitz, JL; Schnizlein-Bick, CT; Spritzler, J; Squires, KE | 1 |
| Blanquet, D; Hage, F; Hallard, M; Mathe, G; Morette, C; Pontiggia, P | 1 |
| Birkus, G; Cihlar, T; Greenwalt, DE; Hitchcock, MJ | 1 |
| Back, N; Bijen, M; Boucher, CA; de Graaf, L; Keulen, W; Kline, MW; Maxeiner, HG; Nijhuis, M; Schuurman, R; van Wijk, A | 1 |
| Alexander, C; Soldin, SJ; Ting, L; Volosov, A | 1 |
| Klinowska-Skupniewska, J; Prandota-Schoepp, A | 1 |
| Aboulker, JP; Brun-Vezinet, F; Certain, A; Descamps, D; Flandre, P; Gastaut, JA; Goujard, C; Joly, V; Meiffredy, V; Remy, G; Ruffault, A; Yeni, P | 1 |
| Margot, NA; Miller, MD; Naeger, LK | 1 |
| Amin, J; Carr, A; Cooper, DA; Doong, N; Freund, J; Hoy, J; Hudson, J; Law, M; Martin, A; Smith, DE; Workman, C | 1 |
| Domínguez Castellanos, A; Justo Alpañés, E; Orbea Ríos, L | 1 |
| Aukrust, P; Frøland, SS; Kvale, D; Mellbye, OJ; Müller, F; Nordøy, I; Tjønnfjord, GE | 1 |
| Fox, L; Friedland, GH; Havlir, D; Pollard, RB; Richman, D; Smeaton, L; Tebas, P; Tierney, C | 1 |
| Ait-Khaled, M; Amphlett, G; Clotet, B; Katlama, C; Staszewski, S; Stone, C; Tisdale, M | 1 |
| Perronne, C | 1 |
| Antonelli, G; Bambacioni, F; Bellomi, F; Focher, F; Gentile, M; Scagnolari, C; Turriziani, O | 1 |
| Aldamiz-Etxebarría, M; Andonegui Navarro, J | 1 |
| Pendergrass, S; Qazi, S; Richman, D; Uckun, FM; Venkatachalam, TK | 1 |
| Dikalov, S; Haase, CP; Lewis, W; Parker, J; Racine, AK; Raidel, S; Russ, R; Sutliff, RL; Taylor, WR; Weiss, D | 1 |
| Bates, M; Hellmann, NS; Hughes, MD; Katzenstein, DA; Shafer, RW; Shulman, NS; Whitcomb, JM; Winters, MA; Zolopa, AR | 1 |
| Lauenroth-Mai, E; Schlote, F | 1 |
| Empey, K; Pomeroy, C; Romanelli, F | 1 |
| Kang, JX; Sun, XB; Zhao, YF | 1 |
| Fernando, SL; Keogh, GL; Quin, J; Steele, RH; Stojkova, V | 1 |
| Aboulker, JP; Flandre, P; Harel, M; Joly, V; Leturque, N; Meiffredy, V; Yeni, P | 1 |
| Carr, A; Cooper, DA; Hoy, J; Hudson, J; Law, M; Martin, A; Smith, DE | 1 |
| Aboulker, JP; Brun-Vézinet, F; Descamps, D; Flandre, P; Harel, M; Izopet, J; Joly, V; Lastère, S; Meiffrédy, V; Peytavin, G; Tamalet, C; Yéni, P; Zeng, AF | 1 |
| Aubertin, AM; Ciurea, A; Delbederi, Z; Fossey, C; Gavriliu, D; Ladurée, D; Laumond, G; Schmidt, S; Sugeac, E | 1 |
| Brun-Vézinet, F; Calvez, V; Cécile, A; Collin, G; Costagliola, D; Damond, F; Delaugerre, C; Descamps, D; Katlama, C; Marcelin, AG; Matheron, S; Simon, A; Valantin, MA; Yvon, A | 1 |
| Baldanti, F; Galloni, D; Gerna, G; Lilleri, D; Piccinini, G; Seminari, E | 1 |
| Becher, F; Benech, HC; Créminon, CA; Delfraissy, JF; Goujard, CM; Grassi, JJ; Pruvost, AG; Schlemmer, DD | 1 |
| Baldanti, F; Blanca, G; Gerna, G; Hübscher, U; Maga, G; Paolucci, S; Skoblov, AY; Spadari, S; Victorova, L | 1 |
| Graziadei, IW; Koch, RO; Maier, H; Romani, N; Vogel, W; Zangerle, R | 1 |
| Bennett, D; García-Lerma, JG; Heneine, W; Kaplan, JE; MacInnes, H; Nidtha, S; Reid, P; Weinstock, H | 1 |
| Oka, S; Teruya, K | 1 |
| Boretto, J; Canard, B; Deval, J; Selmi, B | 1 |
| Copeland, WC; Lim, SE; Longley, MJ; Ponamarev, MV | 1 |
| Brault, C; Chennebault, JM; Loison, J; Payan, C; Peigne, M | 1 |
| Herrmann, SE; James, IR; John, M; Mallal, SA; McKinnon, EJ; Moore, CB; Nolan, DA; White, AJ | 1 |
| Andron, L; Asmuth, DM; Grady, JJ; Green, S; McKinsey, DS; Pollard, RB; Rossero, R | 1 |
| Gronowitz, JS; Källander, CF; Lennerstrand, J; Malmsten, A; Shao, XW; Sönnerborg, A; Unge, T | 1 |
| Bachiller Luque, P; de Luis Román, DA; Eiros Bouza, JM; Ortega Lafont, M; Ortiz de Lejarazu, R | 1 |
| Meldrum, J | 1 |
| Derse, D; Hill, SA; Lloyd, PA; McDonald, S; Wykoff, J | 1 |
| Domingo, P; Ordoñez, J; Pérez, A; Rodriguez, J; Sambeat, MA; Vázquez, G | 1 |
| Chuenyam, T; Cooper, D; Emery, S; Lange, J; Phanuphak, P; Ruxrungtham, K; Sirivichayakul, S; Techasathit, W; Ubolyam, S; Ungsedhapand, C | 1 |
| Hammond, EL; Mallal, SA; Mamotte, CD; Martin, AM; Nolan, DA; Pace, CS | 1 |
| Gazzard, BG; Gilleece, Y; Mandalia, S; Pillay, D; Pozniak, AL; Torti, C | 1 |
| Barber, RE; Lonergan, JT; Mathews, WC | 1 |
| Bölske, G; Carnrot, C; Eriksson, S; Wang, L; Wehelie, R | 1 |
| Calvez, V; Delaugerre, C; Katlama, C; Marcelin, AG; Simon, A; Viegas, P; Wirden, M | 1 |
| Back, DJ; Hoggard, PG; Janneh, O; Jones, SP; Khoo, SH; Maher, B; Pirmohamed, M; Tjia, JF | 1 |
| Ajana, F; Alcaraz, I; Bocket, L; Gerard, Y; Goffard, A; Mouton, Y; Viget, N; Wattré, P; Yazdanpanah, Y | 1 |
| Maa, JF; McComsey, G | 1 |
| Becker, MI; D'Aquila, RT; De Gruttola, V; Delapenha, R; Dubé, MP; Fischl, MA; Gedeon, L; Hirsch, MS; Merigan, TC; Murphy, RL; Pettinelli, C; Pollard, RB; Robbins, GK; Shafer, RW; Smeaton, LM; Snyder, SW; van der Horst, C; Vella, S | 1 |
| D'Aquila, RT; De Gruttola, V; Gripshover, BM; Haubrich, R; Hirsch, MS; Johnson, VA; Kaul, P; Martinez, AI; McCarty, SD; Merigan, TC; Morse, GD; Nokta, MA; Robbins, GK; Shafer, RW; Smeaton, LM; Snyder, SW; Swingle, M; Vella, S | 1 |
| Koopmans, PP; ter Hofstede, HJ; Willems, HL | 1 |
| Fisher, RL; Hernandez, JE; Hessenthaler, SM; Lonergan, JT; McComsey, GA; Sension, MG; Shalit, P; Ward, DJ; Williams, VC | 1 |
| Fu, H; Lin, C; Zhao, Y | 1 |
| Agher, R; Ait-Mohand, H; Bricaire, F; Calvez, V; Costagliola, D; Duvivier, C; Ghosn, J; Katlama, C; Marcelin, AG; Myrto, A; Peytavin, G; Schneider, L | 1 |
| Boyle, BA | 1 |
| Pendergrass, S; Qazi, S; Uckun, FM; Venkatachalam, TK | 1 |
| Brew, BJ; Pemberton, L; Ray, J | 1 |
| Amin, J; Hill, A; Law, M; Moyle, G; Sawyer, W | 1 |
| Becker, SL; Danehower, SC; Fusco, GP; Fusco, JS; Graham, NM; Hansen, NI; Justice, AC; Sherrill, BH; Stein, DS | 1 |
| Franco, S; Martínez, MA; Mas, A; Matamoros, T; Menéndez-Arias, L; Vázquez-Alvarez, BM | 1 |
| Pendergrass, S; Qazi, S; Samuel, P; Uckun, FM; Venkatachalam, TK | 1 |
| Boffito, M; Bonora, S; Caci, AM; Conta, F; D'Avolio, A; De Rosa, FG; Di Perri, G; Sciandra, M; Sinicco, A | 1 |
| Amin, J; Carr, A; Cooper, DA; Doong, N; Emery, S; Freund, J; Hoy, J; Martin, A; Ringland, C; Smith, DE; Workman, C | 1 |
| Barrett, H; Bassett, RL; Hazelwood, JD; Johnson, VA; Kuritzkes, DR; Rhodes, RA; Young, RK | 1 |
| Fletcher, CV; McIntosh, K; Nachman, SA; Pelton, S; Stanley, K; Wiznia, A; Yogev, R | 1 |
| Cardiello, P; Cooper, DA; Emery, S; Juengprasert, N; Kroon, ED; Lange, JM; Phanuphak, P; Ratanasuwan, W; Ruxrungtham, K; Siangphoe, U; Srasuebkul, P; Tongtalung, M; Ubolyam, S; Ungsedhapand, C | 1 |
| Chakraborti, AK; Dunge, A; Singh, S | 1 |
| De Clercq, E; Fernández, S; Ferrero, M; Gotor, V; Lazrek, HB; Mohamed, LA; Pannecouque, C; Rochdi, A; Taourirte, M; Vasseur, JJ | 1 |
| Everall, IP; Kandanearatchi, A; Landau, S; Vyakarnam, A | 1 |
| File, TM; Fisher, RL; Hernandez, JE; Hessenthaler, SM; Lindsey, L; Lonergan, JT; McComsey, GA; Shalit, P; Ward, DJ; Williams, VC | 1 |
| Brinkman, K; Casula, M; de Ronde, A; Hulsebosch, HJ; Lange, J; Nieuwkerk, P; Reiss, P; van der Valk, M; van Eck-Smit, B; van Eeden, A; van Kuijk, K; Weverlingz, GJ | 1 |
| Bates, M; Chappey, C; Clair, MS; Fisher, R; Lanier, ER; Parkin, N; Ross, L; Tisdale, M | 1 |
| Antonelli, G; Bambacioni, F; Gianotti, N; Lazzarin, A; Manconi, PE; Turriziani, O | 1 |
| Rosa, U; Sepkowitz, D; Smith, PR; Tripuraneni, NS; Weedon, J | 1 |
| Demeter, LM; Erice, A; Eshleman, SH; Fischl, MA; Hammer, SM; Hellmann, NS; Ribaudo, HJ | 1 |
| Deville-Bonne, D; Faraj, A; Gallois-Montbrun, S; Seclaman, E; Sommadossi, JP; Véron, M | 1 |
| Beckerman, K; Chavers, S; Covington, DL; Dominguez, K; Garcia, P; Ross, B; Sacks, S; Scheuerle, A; Tilson, H; Watts, DH | 1 |
| Bastin, J; Begriche, K; Fromenty, B; Guimont, MC; Igoudjil, A; Laigneau, JP; Lettéron, P; Maisonneuve, C; Pessayre, D | 1 |
| Auclair, M; Capeau, J; Caron, M; Kornprobst, M; Lagathu, C; Lombès, A; Walker, UA | 1 |
| Fu, H; Jiang, YY; Ju, Y; Wu, YW; Xiao, Q; Zhao, YF | 1 |
| Cancio, R; Crespan, E; Hübscher, U; Locatelli, GA; Maga, G; Spadari, S | 1 |
| Cherry, CL; Fisher, RL; Hernandez, JE; Hessenthaler, SM; Hoppel, CL; Lonergan, JT; McComsey, GA; Paulsen, DM; Ross, LL; Ross, ST; Thompson, KA; White-Owen, C; Williams, VC | 1 |
| Aarnoutse, RE; Burger, DM; Verweij-van Wissen, CP | 1 |
| Cherry, CL; Hernandez, J; Lal, L; McComsey, G; McLean, CA; Ross, LL; Thompson, KA; Wesselingh, SL | 1 |
| Cossarizza, A; Ferraresi, R; Galluzzi, L; Mussini, C; Nasi, M; Pinti, M; Prada, N; Salomoni, P; Troiano, L | 1 |
| Andrieux-Meyer, I; Bourgeois, A; Calmy, A; Ciaffi, L; Delaporte, E; Lactuock, B; Laurent, C; Liégeois, F; Mougnutou, R; Mpoudi-Ngolé, E; Nkoué, N; Zekeng, L | 1 |
| Amin, J; Carr, A; Cooper, DA; McAllister, J; Winston, A | 1 |
| Canard, B; Deval, J; Guerreiro, C; Matamoros, T; Menéndez-Arias, L; Mulard, L | 1 |
| James, JS | 1 |
| Qazi, S; Uckun, FM; Venkatachalam, TK | 1 |
| Gonzalez, RG; Hedreen, JC; Lipton, SA; Monti, L; Navia, BA; Rostasy, K | 1 |
| Qazi, S; Samuel, P; Uckun, FM; Venkatachalam, TK | 1 |
| Chêuc, G; Cotte, L; Debord, T; Decazes, JM; Ferchal, F; Journot, V; Madelaine, I; Molina, JM; Pellegrin, I; Rancinan, C; Sombardier, MN | 1 |
| Bouillaud, F; Leibowitch, J; Lesne, A; Leste-Lasserre, T; Mathez, D; Naviaux, RK; Petit, C; Piétri-Rouxel, F; Sonigo, P | 1 |
| Lewis, W | 1 |
| Alston-Smith, BL; Dubé, MP; Kitch, DW; Mulligan, K; Parker, RA | 1 |
| Back, D; Borucki, MJ; Dieterich, D; Gries, JM; Hoggard, PG; Lissen, E; Rodriguez-Torres, M; Soriano, V; Sulkowski, M; Torriani, FJ; Wang, K | 1 |
| Alhassoon, OM; Brown, GG; Ellis, RJ; Gonzalez, R; Grant, I; Letendre, S; McCutchan, JA; Patterson, TL; Schweinsburg, BC; Taylor, MJ; Videen, JS | 1 |
| Engels, JW; Lazrek, HB; Rochdi, A; Taourirte, M; Vasseur, JJ | 1 |
| Back, DJ; Gazzard, BG; Jones, SP; Lebrecht, D; Morelese, J; Moyle, GJ; Pirmohamed, M; Qazi, N; Sutinen, J; Walker, UA; Yki-Jărvinen, H | 1 |
| Nolan, D | 1 |
| Borderi, M | 1 |
| Averitt, D; Kumar, PN; Pakes, GE; Pappa, KA; Rodriguez-French, A; Shaefer, MS; Tashima, KT; Thompson, MA; Wannamaker, PG; Williams, VC | 1 |
| Chu, CK; Gadthula, S; Schinazi, RF | 1 |
| Blanco, R; Delgado, W; García, H; García, R; Meléndez, M; Rodríguez, JF; Rosario, O; Santana, J | 1 |
| Bienstock, RJ; Copeland, WC; Haase, CP; Hosseini, SH; Kohler, JJ; Lewis, W; Ludaway, T; McNaught, J; Russ, R; Santoianni, R; Stuart, T | 1 |
| Kiseleva, IaIu; Pliasunova, OA; Pokrovskaia, NV; Pokrovskiĭ, AG | 1 |
| Barberá Farré, JR; Beato Pérez, JL; Cuadra García-Tenorio, F; Geijo Martínez, MP; Maciá Martínez, MA; Marcos Sánchez, F; Martínez Alfaro, E; Moreno Mendaña, JM; Rodríguez Zapata, M; Sanz Moreno, J; Sanz Sanz, J; Solera Santos, J | 1 |
| Koh, MT | 1 |
| Gray, G; Jivkov, B; Ledeine, JM; McIntyre, J; Reynolds, L; Schnittman, S; Violari, A | 1 |
| Becher, F; Benech, H; Grassi, JJ; Pruvost, A | 1 |
| Bien, D; Boyd, MA; Carr, A; Cooper, DA; Krisanachinda, A; Lange, JM; Law, M; Lerdlum, S; Phanuphak, P; Reiss, P; Ruxrungtham, K; Srasuebkul, P; Wangsuphachart, S | 1 |
| Ahlenstiel, G; Altfeld, M; Kaufmann, DE; Kupfer, B; Lichterfeld, M; Mui, SK; Rockstroh, JK; Spengler, U; Vogel, M; Voigt, E; Walker, B | 1 |
| Cartledge, J; Churchill, D; Fakoya, A; Hay, P; Johnson, M; Leen, C; Moyle, GJ; Murphy, M; Reilly, G; Sabin, CA; Scullard, G; Wilkins, E | 1 |
| Andreotti, M; Ceffa, S; Cusato, M; Germano, P; Giuliano, M; Guidotti, G; Liotta, G; Loureiro, S; Mancini, MG; Marazzi, MC; Palombi, L; Pirillo, MF; Regazzi, M; Vella, S; Villani, P | 1 |
| Cecelia, AJ; Kumarasamy, N; Mayer, K; Saghayam, S; Solomon, S; Wanke, C | 1 |
| Amellal, B; Calvez, V; Castro, ND; Chêne, G; Cotte, L; Gourlain, K; Journot, V; Molina, JM; Palmer, P; Pédrono, G; Rancinan, C | 1 |
| Samuels, DC | 1 |
| Baba, M; Cheng, YC; Dutschman, GE; Hsu, CH; Hu, R; Krishnan, P; Tanaka, H; Yang, G | 1 |
| Gibb, DM; Grosskurth, H; Khoo, S; Kikaire, B; Mugyenyi, P; Munderi, P; Namale, L; Reid, A; Ssali, F; Walker, AS | 1 |
| Teruya, K | 1 |
| Nelson, M; Waters, L | 1 |
| Begley, JA; Blum, MR; Chittick, GE; Hui, J; Wang, LH; Zong, J | 1 |
| Dubé, MP; Grinspoon, SK; Mulligan, K; Parker, RA; Robbins, GK; Roubenoff, R; Tebas, P | 1 |
| Dubé, MP; Grinspoon, SK; Komarow, L; Mulligan, K; Parker, RA; Robbins, GK; Roubenoff, R; Tebas, P | 1 |
| Baldanti, F; Belfiore, A; Campanini, G; Cancio, R; Gerna, G; Maga, G; Paolucci, S | 1 |
| Abdel-Megeed, MF; Kashuba, AD; Rezk, NL | 1 |
| Enejosa, J; Hinkle, J; Kearney, BP; Ramanathan, S; Shen, G | 1 |
| Diquet, B; Goujard, C; Legrand, M; Mentré, F; Panhard, X; Taburet, AM | 1 |
| Bagnis, CI; Bessette, C; Deray, G; Karie, S; Launay-Vacher, V; Tézenas Du Montcel, S; Tostivint, I; Tourret, J; Vigneau, C | 1 |
| Carvalho, AT; Fernandes, PA; Ramos, MJ | 1 |
| Auclair, M; Capeau, J; Caron, M; Frachon, P; Kim, MJ; Lombès, A; Lombès, M; Viengchareun, S | 1 |
| Acosta, EP; Bassett, R; Eron, JJ; Fischl, MA; Johnson, VA; Kuritzkes, DR; Long, MC; Moore, JD; Sommadossi, JP | 1 |
| Easley, KA; Lennox, JL; Lu, C; Ofotokun, I; Smithson, SE | 1 |
| Anderson, AM; Bartlett, JA; Kosinski, AS | 1 |
| Doerries, R; Drechsler, H; Gass, A; Hardmeier, M; Kuhle, J; Mehling, M; Ruegg, S | 1 |
| Côté, HC; Gadawski, I; Papp, E | 1 |
| Bourgeois, A; Calmy, A; Ciaffi, L; Delaporte, E; Kouanfack, C; Koulla-Shiro, S; Laurent, C; Mougnutou, R; Mpoudi-Ngolé, E; Nkoué, N | 1 |
| Aurpibul, L; Puthanakit, T; Sirisanthana, T; Sirisanthana, V | 1 |
| Behrens, GM; Schmidt, RE; Stankov, MV | 2 |
| Gibert, CL; Grunfeld, C; Peng, G; Sharma, S; Shlay, JC | 1 |
| Basseila, GB; Bokilo, AD; Dokekias, AE; Galiba, FO; Malanda, F; Nsitou, MB; Ntsimba, P | 1 |
| Ahmadou Ahidjo, B; Becker, P; Dusé, AG; Marais, E; Veale, R | 1 |
| Balakrishnan, P; Kumarasamy, N; Murugavel, KG; Priya, B; Saghayam, S; Shankar, EM; Solomon, S; Sundaram, M; Venkatesh, KK | 1 |
| Arnould, L; Isaakidis, P; Khem, S; Khim, SA; Kuoch, S; Phe, T; Raguenaud, ME; Reid, T | 1 |
| Cotter, BR; Currier, JS; Dubé, MP; Fichtenbaum, CJ; Gerschenson, M; Komarow, L; Mitchell, CK; Murphy, RL; Parker, RA; Squires, K; Stein, JH; Torriani, FJ | 1 |
| Bélec, L; Charpentier, C; Karmochkine, M; Laureillard, D; Piketty, C; Si-Mohamed, A; Sodqi, M; Weiss, L | 1 |
| Berrisford, AE; Boulle, AM; Jaspan, HB | 1 |
| Chen, SS; Cheng, AK; DeJesus, E; Enejosa, JV; Gallant, JE; Pozniak, AL; Winston, JA | 1 |
| Atté, EF; Rasschaert, F; Reid, T; van Griensven, J; Zachariah, R | 1 |
| Bassit, L; Detorio, MA; Dikalov, S; Hernandez-Santiago, BI; Jones, DP; Kleinhenz, DJ; Kline, ER; Liang, B; Schinazi, RF; Sutliff, RL; Walp, ER | 1 |
| George, C; Jayakumar, B; Lal, L; Yesoda, A | 1 |
| Portilla, J | 1 |
| Brenner, BG; Cox, S; Moisi, D; Oliveira, M; Spira, B; Wainberg, MA | 1 |
| Duy, SV; Hugon-Chapuis, F; Lefebvre-Tournier, I; Périgaud, C; Pichon, V; Puy, JY | 1 |
| Berzins, B; Evans, S; Forand, J; Hafner, R; Murphy, R; Owens, S; Shevitz, A; Tashima, K; Tebas, P; Yarasheski, K; Zhang, J | 1 |
| Ambrose, P; Devaleenol, B; Kumarasamy, N; Manohar, D; Mayer, KH; Poongulali, S; Saghayam, S; Solomon, S; Venkatesh, KK; Yepthomi, T | 1 |
| Castelnuovo, B; Kamya, M; Nanyonjo, A; Ocama, P | 1 |
| Baba, M; Cheng, YC; Tanaka, H; Wang, X | 1 |
| Benn, P; Cartledge, J; Edwards, SG; Linney, A; Moyle, G; Reilly, G; Ruff, C; Sabin, CA; Sauret-Jackson, V | 1 |
| Eriksson, P; Setzer, B; Sevastianova, K; Sievers, M; Sutinen, J; Wågsäter, D; Walker, UA; Yki-Järvinen, H | 1 |
| Cao, YL; Chen, H; Guo, Y; Li, SX | 1 |
| Bruun, J; Clotet, B; Cozzi-Lepri, A; Eg Hansen, AB; Horban, A; Katlama, C; Lundgren, JD; Martinez-Picado, J; Monforte, Ad; Phillips, AN | 1 |
| Boamah, I; Court, MH; Kashuba, AD; Kenu, E; Kwara, A; Lartey, M; Oliver-Commey, J; Rezk, NL | 1 |
| Alemayehu, YK; Bushen, OY; Muluneh, AT | 1 |
| Martínez, MA; Matamoros, T; Menéndez-Arias, L; Nevot, M | 1 |
| Amuron, B; Birungi, J; Bunnell, R; Coutinho, A; Foster, S; Grosskurth, H; Jaffar, S; Kyomuhangi, R; Levin, J; Mermin, J; Nabiryo, C; Namara, G; Ndembi, N; Opio, A; Tappero, JW | 1 |
| Alvarez, K; Balzarini, J; Barral, K; Canard, B; De Michelis, C; Neyts, J; Priet, S; Sire, J | 1 |
| Bender, MA; Flanigan, T; Freedberg, KA; Kumarasamy, N; Lu, Z; Mayer, KH; Schackman, BR; Scott, CA; Walensky, RP; Wang, B | 1 |
| Deshpande, A; Fleury, HJ; Jeannot, AC; Pinson, P; Schrive, MH; Wittkop, L | 1 |
| Asboe, D; Dunn, D; Fearnhill, E; Gazzard, B; Pillay, D; Pozniak, A; Price, H | 1 |
| Butini, L; Cirioni, O; Costantini, A; Giacometti, A; Montroni, M; Scalise, G | 1 |
| Antinori, A; Ciccosanti, F; Corazzari, M; Fimia, GM; Iadevaia, V; Kroemer, G; Malorni, W; Matarrese, P; Pagliarini, V; Perfettini, JL; Piacentini, M; Soldani, F; Tinari, A; Zaccarelli, M | 1 |
| Borum, PR; Brogly, SB; Chernoff, MC; Crain, MJ; Ford-Chatterton, HM; Malee, KM; Meyer, WA; Mitchell, WG; Moye, JH; Oleske, JM; Seage Iii, GR; Van Dyke, RB | 1 |
| Akarawut, W; Prasanchaimontri, IO; Wattananat, T | 1 |
| Laclair, DD; McKee, EE; Morris, GW | 1 |
| Deribew, A; Shurie, JS | 1 |
| Rutherford, GW; Siegfried, N; Spaulding, A | 1 |
| Cook, A; Divi, RL; Einem, TL; Fletcher, SL; Harbaugh, JW; Harbaugh, SW; Kuo, MM; Nagashima, K; Poirier, MC; Shockley, ME; St Claire, MC | 1 |
| Feng, Y; Huang, J; Huang, Y; Liao, L; Liu, S; Ma, L; Qu, S; Shao, Y; Sun, J; Xing, H; Yu, X; Yuan, L | 1 |
| Betancor, G; Garriga, C; Martínez, MA; Martinez-Picado, J; Menéndez-Arias, L; Nevot, M; Puertas, MC | 1 |
| Castelnuovo, B; Kamya, MR; Kiragga, A; Manabe, Y | 1 |
| Bachani, D; Chan, PL; Deshpande, A; Rajasekaran, S; Rewari, BB; Srikantiah, P | 1 |
| Dhlomo, S; Emery, S; Grandits, G; Khabo, P; Khanyile, T; Komati, S; Magongoa, D; Naidoo, LC; Neaton, JD; Polis, M; Qolohle, D; Ratsela, A | 1 |
| Biwolé-Sida, M; Bork, K; Coudray, M; Cournil, A; Delaporte, E; Essomba, CN; Kouanfack, C; Laurent, C; Tonfack, CA | 1 |
| Cheng, YC; Dutschman, GE; Ghebremichael, M; Grill, SP; Hu, R; Lam, W; Li, FY; Northrup, V; Paintsil, E; Wang, CJ | 1 |
| Breytenbach, JC; Breytenbach, JW; N'Da, DD | 1 |
| Curran, A; Ribera, E | 1 |
| Balzarini, J; Meier, C; Rios Morales, EH | 1 |
| Kisic, M; Martínez, MA; Martinez-Picado, J; Matamoros, T; Mendieta, J; Menéndez-Arias, L; Nevot, M | 1 |
| Cui, J; Fan, A; Gao, X; Liu, Y; Xu, P; Zhang, S; Zhao, Y | 1 |
| Azzoni, L; Firnhaber, C; Foulkes, AS; Fox, L; Glencross, DK; Gross, R; Hunt, G; Montaner, LJ; Morris, L; Sanne, I; Schulze, D; Stevens, W; Van Amsterdam, D; Yin, X | 1 |
| Bygrave, H; Cleary, S; Ford, N; Gadot, L; Goemaere, E; Hilderbrand, K; Jouquet, G; Kranzer, K; Lee, J; Makakole, L; Trivino, L; Vlahakis, N | 1 |
| Calis, JC; de Wit, TF; Geelen, SP; Sigaloff, KC; van Vugt, M | 1 |
| Gu, WB; Han, Y; Li, TS; Li, YL; Qiu, ZF; Wu, P; Xie, J; Zhang, L | 1 |
| Mohiuddin, S; Rajesh, R; Varma, DM; Vidyasagar, S | 1 |
| Aurpibul, L; Puthanakit, T; Sirisanthana, T; Sirisanthana, V; Taejaroenkul, S | 1 |
| Arenas-Pinto, A; Bolhaar, M; Bradman, N; Ekong, R; Grant, A; Ingram, C; Karstaedt, A; Reiss, P; Telisinghe, L; Weber, R; Weller, I | 1 |
| Agu, KA; Akpoigbe, KJ; Badru, T; Chabikuli, O; Eluwa, GI; Hamelmann, C | 1 |
| Lovett, ST; Seier, T; Zeiger, DM; Zilberberg, G | 1 |
| Benki-Nugent, SF; Chung, MH; Etyang, A; John-Stewart, GC; Kohler, PK; McGrath, CJ; Njoroge, J; Thiga, JW | 1 |
| McCann, KA; McKee, EE; Williams, DW | 1 |
| Deshpande, A; Fleury, H; Papuchon, J; Recordon-Pinson, P; Reigadas, S | 1 |
| Didierlaurent, L; Ducloux, C; Goldschmidt, V; Isel, C; Marquet, R; Mougel, M | 1 |
| Carda-Broch, S; Casas-Breva, I; Esteve-Romero, J; Peris-Vicente, J; Rambla-Alegre, M | 1 |
| Espiridião, S; Kulay, L; Moreira de Carvalho, A; Pereira Fontes, TM; Restum Antonio, E; Simões, RS; Uchiyama Nakamurau, M | 1 |
| Bauerfeind, R; Behrens, GM; Binz, A; Leverkus, M; Panayotova-Dimitrova, D; Stankov, MV; Vondran, FW | 1 |
| Bonovas, S; Hatzakis, A; Nikolopoulos, G; Tsiodras, S | 1 |
| Chaiwarith, R; Kotarathitithum, W; Nuntachit, N; Praparattanapan, J; Sirisanthana, T; Supparatpinyo, K | 1 |
| Behrens, GM; Leverkus, M; Panayotova-Dimitrova, D; Schmidt, RE; Stankov, MV | 1 |
| Côté, HC; Hukezalie, KR; Thumati, NR; Wong, JM | 1 |
| Agbaji, O; Ekong, E; Graham, C; Hawkins, C; Idoko, J; Kanki, P; Meloni, S; Muazu, M; Murphy, R; Nimzing, L; Sankalé, JL; Thio, CL | 1 |
| Ananworanich, J; Chomchey, N; Gerschenson, M; Hongchookiat, P; Jadwattanakul, T; Kerr, SJ; Kim, JH; Mathajittiphun, P; Phanuphak, N; Phanuphak, P; Pinyakorn, S; Praihirunyakit, P; Rungrojrat, P; Shikuma, C; Teeratakulpisarn, N; Valcour, V | 1 |
| Adedokun, O; Badru, T; Chabikuli, O; Khamofu, H; Kuti, O; Odafe, S; Ogbanufe, O; Okechukwu, E; Oladele, EA; Torpey, K | 1 |
| Han, Y; Li, TS; Li, YL; Qiu, ZF; Song, XJ; Su, YB; Xie, J; Yu, W | 1 |
| Fekade, D; Feleke, Y; Mezegebu, Y | 1 |
| Campbell, GR; Pallack, ZT; Spector, SA | 1 |
| Lynen, L; Phe, T; Sok, S; Thai, S; van Griensven, J; Veng, C | 1 |
| Arnett, DK; Bagchi, S; Chi, BH; Heimburger, DC; Kabagambe, EK; Kiage, JN; Koethe, JR; Nyirenda, CK; Wellons, MF | 1 |
| Brew, BJ; Cheng, WJ; Churchill, MJ; Ellett, AM; Gorry, PR; Gray, LR; Guillemin, GJ; Roche, MJ; Tachedjian, G; Turville, SG; Wesselingh, SL | 1 |
| Aghokeng, A; Belec, L; Bertagnolio, S; Bunupuradah, T; Burda, S; Cane, P; Cappelli, G; Charpentier, C; Dagnra, AY; de Wit, TF; Deshpande, AK; El-Katib, Z; Eshleman, SH; Fleury, HJ; Fokam, J; Ford, N; Gody, JC; Hamers, RL; Hawkins, CA; Holmes, S; Hosseinipour, MC; Jordan, MR; Kanki, PJ; Katzenstein, D; Koyalta, DD; Kumwenda, JJ; Lallemant, M; Lynen, L; Manosuthi, W; Marconi, VC; Margot, NA; Moussa, S; Ndung'u, T; Ngo-Giang-Huong, N; Nyambi, PN; Orrell, C; Peeters, M; Rhee, SY; Ruxrungtham, K; Schapiro, JM; Schuurman, R; Shafer, RW; Sigaloff, KC; Sirivichayakul, S; Smith, D; Stevens, W; Tang, MW; van Zyl, GU; Wallis, CL; Zolfo, M | 1 |
| Charalambous, S; Churchyard, GJ; Grant, AD; Hoffmann, CJ; Lewis, JJ; Velen, K | 1 |
| Chamnanchanunt, S; Chierakul, W; Desakorn, V; Kiertiburanakul, S; Kyaw, NL; Manosuthi, W; Pitisuttithum, P; Sungkanuparph, S; Thanachartwet, V | 1 |
| Massawe, A; Mghamba, FW; Minzi, OM; Sasi, P | 1 |
| Ampofo, WK; Barnor, JS; Brandful, JA; Ibe, S; Ishikawa, K; Nii-Trebi, NI; Ofori, SB; Sugiura, W; Yamaoka, S | 1 |
| de Oliveira, T; Lessells, RJ; Manasa, J; McGrath, N; Naidu, KK; Newell, ML; Skingsley, A | 1 |
| Ferradini, L; Madec, Y; Nerrienet, E; Ngo-Giang-Huong, N; Nouhin, J | 1 |
| Gong, S; Li, X; Liu, G; Peng, L; Shen, L; Sun, Q | 1 |
| Boulle, A; Chi, BH; Chimbetete, C; Egger, M; Fox, MP; Gerber, F; Gsponer, T; Hoffmann, CJ; Orrell, C; Prozesky, H; Rohr, J; Wandeler, G; Zwahlen, M | 1 |
| Lu, H; Qi, T; Shen, Y; Wang, J; Wang, Z | 1 |
| Bai, J; Gao, G; Guo, F; Han, Y; He, Y; Huang, A; Lei, J; Li, T; Li, Y; Lu, H; Luo, L; Lye, W; Sun, Y; Tang, X; Wang, H; Wu, X; Xie, J; Zhang, C; Zhang, T; Zhang, X | 1 |
| Doumbo, OK; Guirou, EA; Hendrix, CW; Kayentao, K; Nyunt, MM; Parsons, TL; Plowe, CV; Venkatesan, M | 1 |
| Chen, D; Chen, X; Ding, W; Gao, Z; Jin, R; Qiao, L; Song, F; Yang, S; Zhang, Y | 1 |
| Bharti, A; Chakravarty, J; Goel, R; Meena, LP; Rai, M; Sundar, S; Tiwary, NK | 1 |
| Choun, K; De Weggheleire, A; Lynen, L; Phirum, L; Thai, S; van Griensven, J | 1 |
| Clifford, DB; Haas, DW; Johnson, DH; Leger, PD; Li, J; McLaren, PJ; Robbins, GK; Shafer, RW | 1 |
| Aghokeng, AF; Chia, JE; Delaporte, E; Einterz, E; Eymard-Duvernay, S; Molina, JM; Mpoudi-Ngole, E; Peeters, M; Taieb, F | 1 |
| Abongomera, G; Arach, B; Asiimwe, AR; Cook, A; Gibb, DM; Kabamba, D; Kayiwa, J; Kekitiinwa, A; Kenny, J; Kityo, C; Klein, N; Komunyena, J; Mirembe, G; Mulenga, V; Musiime, V; Nansubuga, C; Walker, SA; Wavamunno, P; Zangata, D | 1 |
| Crowe, SM; David, M; Gare, J; Hearps, AC; Imara, U; Kaima, P; Kelly-Hanku, A; Kombati, Z; Ryan, CE; Siba, PM; Timbi, D | 1 |
| Holla, P; Jameel, S; Munshi, SU; Panda, H; Rewari, BB | 1 |
| Bloch, N; Huber, AD; Ji, J; Kirby, KA; Landau, NR; Leslie, MD; Lucas, AD; Michailidis, E; Ong, YT; Puray-Chavez, MN; Sarafianos, SG; Schultz, ML | 1 |
| Gui, T; Guo, W; Jia, L; Jiao, L; Li, H; Li, J; Li, L; Liu, S; Liu, Y; Zhuang, D | 1 |
| Badia, R; Ballana, E; Clotet, B; Esté, JA; Martí, R; Pauls, E; Riveira-Muñoz, E; Ruiz, A; Terradas, G; Torres-Torronteras, J | 1 |
| Bekolo, CE; Bekoule, PS; Djidjou, H; Kollo, B; Sonkoue, C | 1 |
| Guo, F; Li, T; Lin, Q; Shao, H; Sun, P; Tian, J; Xu, Y; Yu, W; Zhou, X | 1 |
| Gilks, CF; Kikaire, B; Kiwuwa-Muyingo, S; Levin, JB; Mambule, I; Musana, H; Musoro, G; Walker, AS | 1 |
| Havens, PL; Hazra, R | 1 |
| Chuturgoon, A; Nagiah, S; Phulukdaree, A | 1 |
| Arterburn, S; Castaño, E; Cheng, AK; Chuck, SL; Church, J; Deville, J; Enejosa, JV; Estripeaut, D; Gaur, A; Rathore, M; Rhee, MS; Saez-Llorens, X; White, K | 1 |
| Fan, P; Li, J; Li, N; Liang, Y; Ma, Y; Sun, D; Wang, Z; Yang, W; Zhu, Q | 1 |
| Brul, S; de Boer, R; De Vos, WH; Manders, EM; Smith, RL; van der Spek, H | 1 |
| Ananworanich, J; Bennett, K; Chomchey, N; DeGruttola, V; Ebenezer, G; Gerschenson, M; Hauer, P; Hongchookiat, P; Jadwattanakul, T; Mathajittiphun, P; McArthur, JC; Nakamoto, B; Phanuphak, N; Phanuphak, P; Praihirunkit, P; Shikuma, CM; Teeratakulpisarn, N | 1 |
| Chen, D; Chen, J; Guo, H; Liang, Q; Qiao, L; Wang, B; Wu, J; Xu, B; Yang, S; Zhang, H; Zhang, Y | 1 |
| Antony, J; Arumugam, K; D'Souza, G; De Costa, A; Kumar, DS; Kumarasamy, N; Poongulali, S; Rewari, BB; Shastri, S; Shet, A | 1 |
| Abongomera, G; Asiimwe, A; Burger, D; Chabala, C; Chintu, C; Cook, AD; Gibb, DM; Kekitiinwa, A; Kenny, J; Kityo, C; Klein, N; McIlleron, H; Mirembe, G; Mulenga, V; Musiime, V; Owen-Powell, E; Thomason, MJ; Walker, AS | 1 |
| Cai, W; Caughey, B; Chung, C; Dai, Z; Hu, F; Lan, Y; Li, L; Tang, X; Zhang, K | 1 |
| Restrepo Valencia, P; Rojas Gómez, R | 1 |
| Adebiyi, OA; Adebiyi, OO; Owira, PM | 1 |
| Maharaj, N; Moodley, D; Moodley, T; Sartorius, B; Sebitloane, M | 1 |
| Fan, P; Li, N; Liang, Y; Nie, Y; Sun, D; Wang, Z; Yang, W; Zhu, Q | 1 |
| Chuturgoon, AA; Nagiah, S; Phulukdaree, A | 1 |
| Emanuel, EJ; Persad, GC | 1 |
| Goryaeva, MP; Gulyaeva, SS; Minaeva, SV; Moshkovich, GF; Tichonova, EV; Varlova, LW | 1 |
| Belyhun, Y; Liebert, UG; Maier, M | 1 |
| Birbal, S; Dheda, M; Ojewole, E; Oosthuizen, F | 1 |
| Abach, J; Abongomera, G; Chabala, C; Colebunders, R; Cook, A; Gibb, DM; Kekitiinwa, A; Kityo, C; Lamorde, M; Mulenga, V; Musiime, V; Thomason, M; Walker, AS | 1 |
| Bor, J; Boulle, A; Brennan, AT; Davies, MA; de Rekeneire, N; Fatti, G; Fox, MP; Leroy, V; Prozesky, H; Sikazwe, I; Stinson, K; Tanser, F; Wandeler, G; Wood, R; Wool-Kaloustian, K; Yuannoutsos, C | 1 |
| Brophy, JC; Chan, AK; Hawkes, MT; Mateyu, G; Mwinjiwa, E; Sodhi, SK | 1 |
| Behrens, GM; Jablonka, A; Kimani, J; Ndakala, FN; Oluka, MN; Oyugi, JO | 1 |
| Boulle, A; Cohen, K; Davies, MA; de Waal, R; Fortuin-de Smidt, M; Igumbor, EU; Maartens, G; Stinson, K; Technau, KG | 1 |
| Conrad, F; Govender, M; Maartens, G; Manning, K; Papavarnavas, NS | 1 |
| Abad-Carrillo, MA; Álvarez-Ríos, AI; Bernal-Morell, E; Genebat, M; González-García, J; Herrero-Fernández, I; Leal, M; Montero, M; Pacheco, YM; Pulido, F; Rosado-Sánchez, I; Ruiz-Mateos, E; Vidal, F | 1 |
| Awoke, T; Birlie, B; Braekers, R; Kasim, A; Shkedy, Z | 1 |
| He, C; Kan, W; Leng, X; Liang, S; Liao, L; Liu, P; Ma, Y; Marconi, VC; Ruan, Y; Shao, Y; Sun, G; Tang, H; Teng, T; Wall, KM; Xing, H; Zuohela, T | 1 |
| Contreras-Galindo, R; Dube, D; Fujinaga, K; Kaplan, MH; Markovitz, DM | 1 |
| Ankrah, DNA; Lartey, M; Leufkens, HGM; Mantel-Teeuwisse, AK | 1 |
| Arudo, J; Barry, M; Hodgkinson, LM; Makori, J; Okwiri, J; Tsisiche, C | 1 |
| Kimani, J; Ndakala, FN; Norbert Behrens, GM; Oluka, MN; Oyugi, JO | 1 |
| Aroke, D; Bechem, NN; Dimala, CA; Kadia, BM | 1 |
| Cuong, DD; Dung, NT; Dung, NTH; Haneuse, S; Kinh, NV; Matsumoto, S; Oka, S; Tanuma, J; Thuy, PTT; Trung, NV; Vu, TV | 1 |
| Antony, J; Ashoor, HM; Blondal, E; Finkelstein, Y; Ghassemi, M; Gough, K; Hemmelgarn, BR; Hutton, B; Ivory, JD; Khan, PA; Lillie, E; Straus, SE; Tricco, AC; Vafaei, A; Veroniki, AA | 1 |
| Balakrishnan, P; Boobalan, J; Chitra, DA; Dinesha, TR; Mothi, SN; Poongulali, S; Saravanan, S; Solomon, S; Solomon, SS; Srirama, RB; Subashini, D | 1 |
| Kan, W; Leng, X; Liao, L; Liu, P; Ruan, Y; Shao, Y; Wang, J; Xing, H; Xu, W; Yan, J; You, Y; Zuo, Z | 1 |
| Ablaeva, J; Antoch, MP; Cohen, HY; De Cecco, M; Gladyshev, VN; Gonzalez, RS; Gorbunova, V; Gudkov, AV; Helfand, SL; Ke, Z; Kogan, V; Leonova, KI; Meer, MV; Neretti, N; Roichman, A; Sedivy, JM; Seluanov, A; Simon, M; Taguchi, T; Van Meter, M | 1 |
| Billong, SC; Cappelli, G; Ceccherini-Silberstein, F; Colizzi, V; Dambaya, B; Fokam, J; Fokunang, CN; Gori, C; Nanfack, AJ; Ndjolo, A; Perno, CF; Salpini, R; Santoro, MM; Sosso, SM; Takou, D; Teto, G | 1 |
| Huang, JP; Huang, WH; Luo, SD; Luo, XL; Mo, LD; Ni, ZY; Su, GS; Su, HZ; Wu, JY | 1 |
| Kammarabutr, J; Mahalapbutr, P; Okumura, H; Rungrotmongkol, T; Wolschann, P | 1 |
| Eggers, C; Hoetelmans, R; Läer, S | 1 |
| Apalata, T; Bam, NE; Chitha, W; Mabunda, SA; Nomatshila, SC; Ntsaba, J | 1 |
| Fernández, S; Ferrero, M; Martín-Nieves, V; Sanghvi, YS | 1 |
| Ge, Z; Mashiach, D; Miller, JH; Shin, J; Singh, S; Yaramada, L | 1 |
| Begovac, J; Šoštarić Zadro, A; Višković, K | 1 |
44 review(s) available for zidovudine and stavudine
| Article | Year |
|---|---|
Natural product-based anti-HIV drug discovery and development facilitated by the NCI developmental therapeutics program.
Topics: Amino Acid Sequence; Anti-HIV Agents; HIV-1; Models, Biological; Models, Chemical; Molecular Sequence Data; National Institutes of Health (U.S.); Retrospective Studies; United States; Virus Replication | 2001 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
[Anti-HIV treatment, today and in the near future].
Topics: Antiviral Agents; Didanosine; Dideoxynucleosides; DNA, Viral; Drug Therapy, Combination; HIV Infections; Humans; Reverse Transcriptase Inhibitors; Stavudine; Transcription, Genetic; Zalcitabine; Zidovudine | 1992 |
Targeted therapy of human immunodeficiency virus-related disease.
Topics: Acquired Immunodeficiency Syndrome; Adenine; Antiviral Agents; CD4 Antigens; Didanosine; Dideoxynucleosides; Dipyridamole; Drug Synergism; Gene Expression Regulation, Viral; Genes, nef; Genes, rev; Genes, tat; HIV; HIV Protease; Interferon Type I; Organophosphonates; RNA-Directed DNA Polymerase; Stavudine; Transcription, Genetic; Zalcitabine; Zidovudine | 1991 |
Pharmacologic therapy for human immunodeficiency virus infection: a review.
Topics: Antiviral Agents; Didanosine; Drug Resistance, Microbial; HIV Infections; HIV Protease Inhibitors; Humans; Reverse Transcriptase Inhibitors; Stavudine; Structure-Activity Relationship; Zidovudine | 1994 |
Pharmacokinetic optimisation of antiretroviral therapy in patients with HIV infection.
Topics: Aging; Antineoplastic Agents; Antiviral Agents; Didanosine; Drug Interactions; Guidelines as Topic; HIV Infections; Humans; Phosphorylation; Racial Groups; Sex Characteristics; Stavudine; Zalcitabine; Zidovudine | 1995 |
An approach to antiretroviral treatment of HIV disease. Nucleoside monotherapy.
Topics: Antiviral Agents; Didanosine; HIV Infections; HIV-1; Humans; Lamivudine; Nucleosides; Stavudine; Zalcitabine; Zidovudine | 1995 |
Human immunodeficiency virus infection in children.
Topics: Adolescent; AIDS-Related Opportunistic Infections; Child; Child, Preschool; Dapsone; Didanosine; Drug Interactions; Drug Therapy, Combination; Female; HIV Infections; Humans; Male; Pentamidine; Pneumonia, Pneumocystis; Pregnancy; Pregnancy Complications, Infectious; Recurrence; Stavudine; Trimethoprim, Sulfamethoxazole Drug Combination; Zalcitabine; Zidovudine | 1995 |
Clinical pharmacokinetics of nucleoside antiretroviral agents.
Topics: Animals; Didanosine; Dideoxynucleosides; HIV Infections; Humans; Lamivudine; Stavudine; Zalcitabine; Zidovudine | 1995 |
[Antiretroviral therapy. Current status and perspectives].
Topics: Antiviral Agents; CD4 Lymphocyte Count; Clinical Trials as Topic; Didanosine; Drug Therapy, Combination; HIV; HIV Infections; Humans; Stavudine; Zalcitabine; Zidovudine | 1994 |
Metabolism and mechanism of antiretroviral action of purine and pyrimidine derivatives.
Topics: Animals; Antiviral Agents; Dideoxyadenosine; Dideoxynucleosides; Humans; Lamivudine; Purines; Pyrimidines; Retroviridae; Spiro Compounds; Stavudine; Thymidine; Uridine; Zalcitabine; Zidovudine | 1994 |
Perspectives on the use of antiretroviral drugs in the treatment of HIV infection.
Topics: Didanosine; Dideoxynucleosides; Drug Administration Schedule; HIV Infections; Humans; Stavudine; Zalcitabine; Zidovudine | 1994 |
Effect of HIV treatment on cognition, behavior, and emotion.
Topics: Acquired Immunodeficiency Syndrome; Cognition Disorders; Cycloserine; Didanosine; Humans; Mental Disorders; Mood Disorders; Stavudine; Zidovudine | 1994 |
Antiretroviral therapy of human immunodeficiency virus type-1 (HIV-1) infection.
Topics: Antiviral Agents; Didanosine; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Reverse Transcriptase Inhibitors; Stavudine; Zalcitabine; Zidovudine | 1995 |
Clinical toxicity of antiretroviral nucleoside analogs.
Topics: Animals; Antiviral Agents; Didanosine; Humans; Lamivudine; Mitochondria; Nucleosides; Stavudine; Zalcitabine; Zidovudine | 1996 |
Guide to major clinical trials of antiretroviral therapy administered to patients infected with human immunodeficiency virus.
Topics: Anti-HIV Agents; Clinical Trials as Topic; Didanosine; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; Humans; Lamivudine; Meta-Analysis as Topic; Reverse Transcriptase Inhibitors; Stavudine; Zalcitabine; Zidovudine | 1996 |
[Nucleoside analogs inhibiting reverse transcriptase: use in adult patient with HIV infection].
Topics: Adult; Anti-HIV Agents; Clinical Trials as Topic; Didanosine; Dideoxynucleosides; Drug Resistance, Microbial; Drug Therapy, Combination; HIV Infections; Humans; Lamivudine; Reverse Transcriptase Inhibitors; Stavudine; Zalcitabine; Zidovudine | 1996 |
Antiretroviral therapy: a guide to the most important trials.
Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Clinical Trials as Topic; Didanosine; Drug Therapy, Combination; HIV Infections; Humans; Indinavir; Lamivudine; Nevirapine; Pyridines; Ritonavir; Saquinavir; Stavudine; Viral Load; Zalcitabine; Zidovudine | 1997 |
[Antiretroviral treatment in human immunodeficiency virus infection].
Topics: Antiviral Agents; Didanosine; Drug Interactions; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Ritonavir; Saquinavir; Stavudine; Treatment Outcome; Viral Load; Zalcitabine; Zidovudine | 1997 |
Antiretroviral chemotherapy.
Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Delavirdine; Didanosine; Dideoxynucleosides; HIV Infections; HIV-1; Humans; Indinavir; Lamivudine; Nelfinavir; Nevirapine; Oxazines; Ritonavir; Saquinavir; Stavudine; Zalcitabine; Zidovudine | 1998 |
Toxicity of antiretroviral agents.
Topics: Anti-HIV Agents; Didanosine; Health Personnel; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Occupational Exposure; Reverse Transcriptase Inhibitors; Ritonavir; Saquinavir; Stavudine; Zalcitabine; Zidovudine | 1997 |
Prevalence and incidence of resistance to zidovudine and other antiretroviral drugs.
Topics: Anti-HIV Agents; Drug Resistance, Microbial; HIV Protease Inhibitors; HIV-1; Humans; Incidence; Indinavir; Lamivudine; Prevalence; Reverse Transcriptase Inhibitors; Risk Factors; Saquinavir; Stavudine; Time Factors; Zidovudine | 1997 |
Peripheral neuropathy with nucleoside antiretrovirals: risk factors, incidence and management.
Topics: Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Didanosine; Drug Therapy, Combination; HIV Infections; Humans; Peripheral Nervous System Diseases; Reverse Transcriptase Inhibitors; Stavudine; Zalcitabine; Zidovudine | 1998 |
Antiretrovirals.
Topics: Adolescent; Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Carbamates; Cyclopropanes; Delavirdine; Didanosine; Dideoxynucleosides; Female; Furans; HIV Infections; Humans; Indinavir; Lamivudine; Nelfinavir; Nevirapine; Oxazines; Pregnancy; Pregnancy Complications, Infectious; Protease Inhibitors; Reverse Transcriptase Inhibitors; Ritonavir; Saquinavir; Stavudine; Sulfonamides; Zalcitabine; Zidovudine | 1999 |
Stavudine plus a non-thymidine nucleoside reverse transcriptase inhibitor as a backbone for highly active antiretroviral therapy.
Topics: Clinical Trials as Topic; Didanosine; Drug Therapy, Combination; HIV Infections; Humans; Lamivudine; Retroviridae; Reverse Transcriptase Inhibitors; Stavudine; Zidovudine | 1998 |
Mechanisms of HIV-1 nucleoside reverse transcriptase inhibitor resistance: is it all figured out?
Topics: Adenine; Adenosine Triphosphate; Anti-HIV Agents; Drug Resistance, Microbial; HIV-1; Mutation; Organophosphonates; Organophosphorus Compounds; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Stavudine; Tenofovir; Zidovudine | 2001 |
[Treatment of chronic hepatitis C in patients coinfected with HIV: tolerability, drug interactions, therapeutic indications].
Topics: Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Clinical Trials as Topic; Didanosine; Drug Interactions; Hepatitis C, Chronic; HIV Infections; Humans; Interferon-alpha; Life Style; Mitochondria; Monitoring, Physiologic; Multicenter Studies as Topic; Patient Selection; Randomized Controlled Trials as Topic; Retrospective Studies; Reverse Transcriptase Inhibitors; Ribavirin; Stavudine; Time Factors; Viral Load; Zidovudine | 2002 |
[Antiretrovirals].
Topics: Acidosis, Lactic; Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Didanosine; Hemophilia A; Hemorrhage; HIV Protease Inhibitors; HIV-Associated Lipodystrophy Syndrome; Humans; Indinavir; Nevirapine; Oxazines; Reverse Transcriptase Inhibitors; Stavudine; Zidovudine | 2003 |
Nucleotide analogue binding, catalysis and primer unblocking in the mechanisms of HIV-1 reverse transcriptase-mediated resistance to nucleoside analogues.
Topics: Anti-HIV Agents; DNA Primers; DNA Repair; Drug Resistance, Multiple, Viral; Genes, pol; HIV Reverse Transcriptase; HIV-1; Models, Molecular; Mutation; Protein Binding; Reverse Transcriptase Inhibitors; Stavudine; Zidovudine | 2003 |
The continuing evolution of HIV therapy.
Topics: Adenine; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Atazanavir Sulfate; Benzoxazines; Carbamates; CD4 Lymphocyte Count; Cyclopropanes; Delayed-Action Preparations; Deoxycytidine; Didanosine; Dideoxynucleosides; Drug Monitoring; Emtricitabine; Furans; HIV Infections; Humans; Lamivudine; Nevirapine; Oligopeptides; Organophosphates; Organophosphonates; Organophosphorus Compounds; Oxazines; Pyridines; Randomized Controlled Trials as Topic; Stavudine; Sulfonamides; Tenofovir; Treatment Outcome; Viral Load; Zidovudine | 2003 |
Changes in hematologic parameters and efficacy of thymidine analogue-based, highly active antiretroviral therapy: a meta-analysis of six prospective, randomized, comparative studies.
Topics: Anemia; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Hemoglobins; HIV Infections; Humans; Neutropenia; Randomized Controlled Trials as Topic; Stavudine; Viral Load; Zidovudine | 2004 |
Prognostic factors in lactic acidosis syndrome caused by nucleoside reverse transcriptase inhibitors: report of eight cases and review of the literature.
Topics: Acidosis, Lactic; Adult; Didanosine; Female; HIV Infections; Humans; Lamivudine; Male; Middle Aged; New York; Reverse Transcriptase Inhibitors; Stavudine; Syndrome; Zidovudine | 2004 |
Nucleoside reverse transcriptase inhibitors, mitochondrial DNA and AIDS therapy.
Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Didanosine; DNA Replication; DNA, Mitochondrial; Humans; Lamivudine; Mitochondria; Nucleosides; Reverse Transcriptase Inhibitors; Stavudine; Zidovudine | 2005 |
Do non-nucleoside reverse transcriptase inhibitors contribute to lipodystrophy?
Topics: Alkynes; Anti-Retroviral Agents; Benzoxazines; Cardiovascular Diseases; Cyclopropanes; HIV Infections; HIV-Associated Lipodystrophy Syndrome; Humans; Metabolic Syndrome; Nevirapine; Oxazines; Randomized Controlled Trials as Topic; Reverse Transcriptase Inhibitors; Risk Factors; Stavudine; Zidovudine | 2005 |
[Use of thymidine-sparing regimens in first-line therapy and in switches from thymidine analogues].
Topics: Anti-HIV Agents; Antiretroviral Therapy, Highly Active; HIV Infections; Humans; Stavudine; Thymidine; Treatment Outcome; Zidovudine | 2005 |
Computational models of antiviral toxicity.
Topics: Anti-HIV Agents; Computer Simulation; Drug-Related Side Effects and Adverse Reactions; HIV Infections; Humans; Lamivudine; Molecular Structure; Stavudine; Zidovudine | 2007 |
[Antiretrovirals].
Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Didanosine; Drug Prescriptions; Drug Therapy, Combination; Humans; Lopinavir; Protease Inhibitors; Pyrimidinones; Reverse Transcriptase Inhibitors; Stavudine; Zidovudine | 2007 |
Long-term complications of antiretroviral therapy: lipoatrophy.
Topics: Anti-HIV Agents; Body Image; Cardiovascular Diseases; Female; HIV-Associated Lipodystrophy Syndrome; Humans; Male; Stavudine; Time Factors; Zidovudine | 2007 |
[Tenofovir as a strategy to avoid or limit adverse effects].
Topics: Adenine; Anemia; Anti-HIV Agents; Antimetabolites; Clinical Trials as Topic; DNA, Mitochondrial; Double-Blind Method; Drug Therapy, Combination; Dyslipidemias; Glucose Metabolism Disorders; HIV Infections; HIV-1; HIV-Associated Lipodystrophy Syndrome; Humans; Multicenter Studies as Topic; Organophosphonates; Prospective Studies; Randomized Controlled Trials as Topic; Reverse Transcriptase Inhibitors; Stavudine; Tenofovir; Thymidine; Zidovudine | 2008 |
Stavudine or zidovudine in three-drug combination therapy for initial treatment of HIV infection in antiretroviral-naïve individuals.
Topics: Adolescent; Adult; Anti-HIV Agents; Child; Child, Preschool; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Randomized Controlled Trials as Topic; Reverse Transcriptase Inhibitors; Stavudine; Young Adult; Zidovudine | 2010 |
From old to new nucleoside reverse transcriptase inhibitors: changes in body fat composition, metabolic parameters and mitochondrial toxicity after the switch from thymidine analogs to tenofovir or abacavir.
Topics: Adenine; Adipose Tissue; Body Composition; Dideoxynucleosides; Drug Substitution; Humans; Metabolism; Mitochondria; Organophosphonates; Reverse Transcriptase Inhibitors; Stavudine; Tenofovir; Thymidine; Zidovudine | 2011 |
HIV-1-resistance-associated mutations after failure of first-line antiretroviral treatment among children in resource-poor regions: a systematic review.
Topics: Adolescent; Africa; Alkynes; Anti-HIV Agents; Asia; Benzoxazines; Child; Child, Preschool; Cross-Sectional Studies; Cyclopropanes; Developing Countries; Drug Resistance, Viral; Female; Health Resources; HIV Infections; HIV-1; Humans; Indinavir; Lamivudine; Latin America; Lopinavir; Male; Mutation; Nevirapine; Pyrimidinones; Reverse Transcriptase Inhibitors; Ritonavir; Stavudine; Treatment Failure; Viral Load; Zidovudine | 2011 |
Antiretrovirals for HIV Exposure Prophylaxis.
Topics: Adenine; Anti-HIV Agents; Deoxycytidine; Dideoxynucleosides; Emtricitabine; HIV; HIV Infections; Humans; Lamivudine; Occupational Exposure; Organophosphonates; Stavudine; Tenofovir; Zidovudine | 2012 |
Comparative safety and effectiveness of perinatal antiretroviral therapies for HIV-infected women and their children: Systematic review and network meta-analysis including different study designs.
Topics: Abnormalities, Drug-Induced; Alkynes; Anti-HIV Agents; Benzoxazines; Child; Congenital Abnormalities; Cyclopropanes; Drug Therapy, Combination; Female; HIV Infections; Humans; Infant; Infant, Low Birth Weight; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Network Meta-Analysis; Nevirapine; Perinatal Care; Pregnancy; Pregnancy Complications, Infectious; Stavudine; Stillbirth; Zidovudine | 2018 |
101 trial(s) available for zidovudine and stavudine
| Article | Year |
|---|---|
Pitt tests new HIV/AIDS drug.
Topics: Antiviral Agents; Dideoxynucleosides; HIV Infections; Humans; Stavudine; Zidovudine | 1992 |
A phase I/II evaluation of stavudine (d4T) in children with human immunodeficiency virus infection.
Topics: Administration, Oral; Adolescent; Adult; Biological Availability; Body Weight; CD4 Lymphocyte Count; Child; Child, Preschool; Disease Progression; Female; Growth; HIV Core Protein p24; HIV Infections; Humans; Infant; Male; Stavudine; Survival Rate; Zidovudine | 1995 |
Stavudine (Zerit). New antiretroviral joins arsenal against HIV.
Topics: Double-Blind Method; HIV Infections; Humans; Stavudine; Zidovudine | 1994 |
D4T nucleoside combinations for HIV.
Topics: Adult; Antiviral Agents; Didanosine; Drug Therapy, Combination; HIV Infections; Humans; Stavudine; Zidovudine | 1996 |
Clinical efficacy of monotherapy with stavudine compared with zidovudine in HIV-infected, zidovudine-experienced patients. A randomized, double-blind, controlled trial. Bristol-Myers Squibb Stavudine/019 Study Group.
Topics: Adult; Anemia; Anti-HIV Agents; CD4 Lymphocyte Count; Disease Progression; Double-Blind Method; Female; HIV Infections; Humans; Male; Nausea; Neutropenia; Stavudine; Vomiting; Zidovudine | 1997 |
A controlled trial of two nucleoside analogues plus indinavir in persons with human immunodeficiency virus infection and CD4 cell counts of 200 per cubic millimeter or less. AIDS Clinical Trials Group 320 Study Team.
Topics: Acquired Immunodeficiency Syndrome; Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Disease Progression; Double-Blind Method; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Indinavir; Lamivudine; Male; Reverse Transcriptase Inhibitors; RNA, Viral; Stavudine; Zidovudine | 1997 |
Stavudine, lamivudine and indinavir in children with advanced HIV-1 infection: preliminary experience.
Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Child; Child, Preschool; Drug Therapy, Combination; Female; HIV Protease Inhibitors; Humans; Indinavir; Infectious Disease Transmission, Vertical; Lamivudine; Male; Pilot Projects; Retrospective Studies; Stavudine; Zidovudine | 1997 |
A randomized comparative trial of stavudine (d4T) versus zidovudine (ZDV, AZT) in children with human immunodeficiency virus infection. AIDS Clinical Trials Group 240 Team.
Topics: Anti-HIV Agents; Bias; CD4 Lymphocyte Count; Child; Child, Preschool; Disease Progression; Double-Blind Method; Female; Follow-Up Studies; HIV Infections; Humans; Infant; Male; Neutropenia; Stavudine; Zidovudine | 1998 |
Antiviral effect of double and triple drug combinations amongst HIV-infected adults: lessons from the implementation of viral load-driven antiretroviral therapy.
Topics: Adult; Anti-HIV Agents; Cohort Studies; Didanosine; Drug Therapy, Combination; Female; HIV Infections; Humans; Lamivudine; Male; Multivariate Analysis; Stavudine; Viral Load; Zalcitabine; Zidovudine | 1998 |
An open randomized controlled trial of zidovudine plus lamivudine versus stavudine plus lamivudine.
Topics: Adult; CD4 Lymphocyte Count; CD8-Positive T-Lymphocytes; Drug Therapy, Combination; HIV; HIV Infections; HIV Protease Inhibitors; Homosexuality, Male; Humans; Indinavir; Lamivudine; Male; Middle Aged; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; RNA, Viral; Stavudine; Treatment Outcome; Viral Load; Zidovudine | 1998 |
Eradication of AIDS-related disseminated mycobacterium avium complex infection after 12 months of antimycobacterial therapy combined with highly active antiretroviral therapy.
Topics: Adult; AIDS-Related Opportunistic Infections; Anti-Bacterial Agents; Anti-HIV Agents; Clarithromycin; Drug Therapy, Combination; Ethambutol; Female; Humans; Lamivudine; Male; Mycobacterium avium Complex; Mycobacterium avium-intracellulare Infection; Rifabutin; Stavudine; Zidovudine | 1998 |
Cerebrospinal-fluid HIV-1 RNA and drug concentrations after treatment with lamivudine plus zidovudine or stavudine.
Topics: Adult; AIDS Dementia Complex; Analysis of Variance; Anti-HIV Agents; CD4 Lymphocyte Count; Chromatography, High Pressure Liquid; Drug Combinations; Follow-Up Studies; HIV Core Protein p24; HIV Infections; HIV-1; Humans; Lamivudine; Middle Aged; RNA, Viral; Spinal Puncture; Stavudine; Zidovudine | 1998 |
The ALBI trial: a randomized controlled trial comparing stavudine plus didanosine with zidovudine plus lamivudine and a regimen alternating both combinations in previously untreated patients infected with human immunodeficiency virus.
Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Didanosine; Drug Administration Schedule; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Reverse Transcriptase Inhibitors; RNA, Viral; Stavudine; Treatment Outcome; Viremia; Zidovudine | 1999 |
Lamivudine in combination with zidovudine, stavudine, or didanosine in patients with HIV-1 infection. A randomized, double-blind, placebo-controlled trial. National Institute of Allergy and Infectious Disease AIDS Clinical Trials Group Protocol 306 Invest
Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Didanosine; Double-Blind Method; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Reverse Transcriptase Inhibitors; RNA, Viral; Stavudine; Viral Load; Zidovudine | 1999 |
Long-term effects of antiretroviral combination therapy on HIV type 1 DNA levels.
Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; CD8-Positive T-Lymphocytes; Data Interpretation, Statistical; Didanosine; DNA, Viral; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Middle Aged; Polymerase Chain Reaction; RNA, Viral; Stavudine; Time Factors; Zidovudine | 1999 |
Preliminary experiences with triple therapy including nelfinavir and two reverse transcriptase inhibitors in previously untreated HIV-infected children.
Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Child; Child, Preschool; Didanosine; Drug Therapy, Combination; Female; HIV Infections; Humans; Infant; Lamivudine; Male; Nelfinavir; Prospective Studies; Reverse Transcriptase Inhibitors; Stavudine; Viral Load; Zidovudine | 1999 |
Evidence of stavudine-related phenotypic resistance among zidovudine-pretreated HIV-1-infected subjects receiving a therapeutic regimen of stavudine plus lamivudine.
Topics: Anti-HIV Agents; Drug Resistance, Microbial; Drug Therapy, Combination; Genotype; HIV Infections; HIV-1; Humans; Lamivudine; Molecular Sequence Data; Phenotype; Prospective Studies; Reverse Transcriptase Inhibitors; RNA, Viral; Stavudine; Zidovudine | 1999 |
Mutations conferring resistance to zidovudine diminish the antiviral effect of stavudine plus didanosine.
Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Didanosine; Drug Resistance; Drug Therapy, Combination; Female; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Male; Mutation; Pilot Projects; Reverse Transcriptase Inhibitors; RNA, Viral; Stavudine; Zidovudine | 1999 |
A randomized study comparing triple versus double antiretroviral therapy or no treatment in HIV-1-infected patients in very early stage disease: the Spanish Earth-1 study.
Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; CD4-CD8 Ratio; Didanosine; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Palatine Tonsil; Ritonavir; RNA, Viral; Spain; Stavudine; Viremia; Zalcitabine; Zidovudine | 1999 |
Cerebrospinal fluid beta2-microglobulin, monocyte chemotactic protein-1, and soluble tumour necrosis factor alpha receptors before and after treatment with lamivudine plus zidovudine or stavudine.
Topics: Adult; Anti-HIV Agents; beta 2-Microglobulin; Chemokine CCL2; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Lamivudine; Middle Aged; Receptors, Tumor Necrosis Factor; Solubility; Stavudine; Zidovudine | 2000 |
Nucleoside analogs plus ritonavir in stable antiretroviral therapy-experienced HIV-infected children: a randomized controlled trial. Pediatric AIDS Clinical Trials Group 338 Study Team.
Topics: Adolescent; Anti-HIV Agents; CD4 Lymphocyte Count; Child; Child, Preschool; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Male; Reverse Transcriptase Inhibitors; Ritonavir; RNA, Viral; Stavudine; Viral Load; Zidovudine | 2000 |
Human immunodeficiency virus-infected persons with mutations conferring resistance to zidovudine show reduced virologic responses to hydroxyurea and stavudine-lamivudine.
Topics: Anti-HIV Agents; Drug Resistance, Microbial; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Hydroxyurea; Lamivudine; Logistic Models; Mutation; Nucleic Acid Synthesis Inhibitors; Reverse Transcriptase Inhibitors; Stavudine; Viral Load; Zidovudine | 2000 |
A randomized, controlled, phase II trial comparing escalating doses of subcutaneous interleukin-2 plus antiretrovirals versus antiretrovirals alone in human immunodeficiency virus-infected patients with CD4+ cell counts >/=350/mm3.
Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; CD8-Positive T-Lymphocytes; Didanosine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; HIV Infections; Humans; Indinavir; Injections, Subcutaneous; Interleukin-2; Lamivudine; Lymphocyte Count; Male; Nelfinavir; Nevirapine; Ritonavir; RNA, Viral; Saquinavir; Stavudine; Zalcitabine; Zidovudine | 2000 |
Dual nucleoside regimens in nonadvanced HIV infection: prospective follow-up of 130 patients, Aquitaine Cohort, 1996 to 1998. Groupe d'Epidémiologie Clinique du SIDA en Aquitaine (GECSA).
Topics: AIDS-Related Opportunistic Infections; Anti-HIV Agents; CD4 Lymphocyte Count; Cohort Studies; Didanosine; Drug Therapy, Combination; Follow-Up Studies; HIV Infections; HIV-1; Humans; Lamivudine; Multivariate Analysis; Prospective Studies; Reverse Transcriptase Inhibitors; RNA, Viral; Stavudine; Treatment Outcome; Zalcitabine; Zidovudine | 2000 |
In vivo antagonism with zidovudine plus stavudine combination therapy.
Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Drug Therapy, Combination; Female; HIV; HIV Infections; Humans; Male; RNA, Viral; Stavudine; Zidovudine | 2000 |
A randomised, open-label comparison of three highly active antiretroviral therapy regimens including two nucleoside analogues and indinavir for previously untreated HIV-1 infection: the OzCombo1 study.
Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Australia; CD4 Lymphocyte Count; Didanosine; Female; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Male; Stavudine; Viral Load; Zidovudine | 2000 |
Recovery of replication-competent virus from CD4 T cell reservoirs and change in coreceptor use in human immunodeficiency virus type 1-infected children responding to highly active antiretroviral therapy.
Topics: Adolescent; CD4-Positive T-Lymphocytes; Cell Differentiation; Child; Coculture Techniques; Female; HIV Infections; HIV-1; Humans; Immunophenotyping; Infant; Lamivudine; Leukocytes, Mononuclear; Male; Nelfinavir; Prospective Studies; Receptors, CCR5; Receptors, CXCR4; Reverse Transcriptase Inhibitors; Ritonavir; Stavudine; Viral Load; Virus Replication; Zidovudine | 2000 |
Continued lamivudine versus delavirdine in combination with indinavir and zidovudine or stavudine in lamivudine-experienced patients: results of Adult AIDS Clinical Trials Group protocol 370.
Topics: Acquired Immunodeficiency Syndrome; Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Delavirdine; Female; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Male; Reverse Transcriptase Inhibitors; Stavudine; Time Factors; Viral Load; Zidovudine | 2000 |
A comparison of stavudine plus lamivudine versus zidovudine plus lamivudine in combination with indinavir in antiretroviral naive individuals with HIV infection: selection of thymidine analog regimen therapy (START I).
Topics: Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Female; Follow-Up Studies; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Indinavir; Lamivudine; Male; Reverse Transcriptase Inhibitors; RNA, Viral; Stavudine; Thymidine; Zidovudine | 2000 |
A comparison of stavudine, didanosine and indinavir with zidovudine, lamivudine and indinavir for the initial treatment of HIV-1 infected individuals: selection of thymidine analog regimen therapy (START II).
Topics: Adolescent; Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Didanosine; Dideoxynucleosides; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Indinavir; Lamivudine; Male; Reverse Transcriptase Inhibitors; Stavudine; Thymidine; Viral Load; Zidovudine | 2000 |
Didanosine dosed once daily is equivalent to twice daily dosing for patients on double or triple combination antiretroviral therapy. The AI454-147 Team.
Topics: Adult; Anti-HIV Agents; Didanosine; Drug Administration Schedule; Drug Therapy, Combination; Female; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Male; Middle Aged; Mutation; Reverse Transcriptase Inhibitors; RNA, Viral; Stavudine; Treatment Outcome; Zidovudine | 2000 |
Comparison of immunologic restoration and virologic response in plasma, tonsillar tissue, and cerebrospinal fluid in HIV-1-infected patients treated with double versus triple antiretroviral therapy in very early stages: The Spanish EARTH-2 Study. Early An
Topics: Adult; Blood; CD4 Lymphocyte Count; Cell Count; Cerebrospinal Fluid; Cerebrospinal Fluid Proteins; Cohort Studies; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Male; Palatine Tonsil; Point Mutation; Reverse Transcriptase Inhibitors; RNA, Viral; Spain; Stavudine; Time Factors; Viral Load; Zidovudine | 2000 |
Influence of prior exposure to zidovudine on stavudine phosphorylation in vivo and ex vivo.
Topics: Anti-HIV Agents; Chromatography, High Pressure Liquid; Female; HIV Seropositivity; Humans; Male; Monocytes; Phosphorylation; Stavudine; Zidovudine | 2001 |
Zidovudine and stavudine sequencing in HIV treatment planning: findings from the CHORUS HIV cohort.
Topics: Adolescent; Adult; Aged; Anti-HIV Agents; CD4 Lymphocyte Count; Drug Administration Schedule; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Homosexuality; Humans; Logistic Models; Longitudinal Studies; Male; Middle Aged; Reverse Transcriptase Inhibitors; RNA, Viral; Stavudine; Thymidine; White People; Zidovudine | 2001 |
Therapeutic effects of nucleoside analogues on psychomotor slowing in HIV infection.
Topics: Adult; Anti-HIV Agents; Central Nervous System Diseases; Didanosine; Drug Therapy, Combination; Female; HIV Infections; HIV Seropositivity; HIV-1; Humans; Lamivudine; Male; Middle Aged; Motor Skills; Stavudine; Zalcitabine; Zidovudine | 2001 |
An open-label randomized trial to evaluate different therapeutic strategies of combination therapy in HIV-1 infection: design, rationale, and methods of the initio trial.
Topics: Adult; Didanosine; Dideoxynucleosides; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Middle Aged; Nelfinavir; Patient Selection; Randomized Controlled Trials as Topic; Research Design; Ritonavir; Sample Size; Saquinavir; Stavudine; Zidovudine | 2001 |
Phase II/III Trials of Viracept start.
Topics: Anti-HIV Agents; Blood; CD4 Lymphocyte Count; Drug Therapy, Combination; HIV; HIV Infections; HIV Protease Inhibitors; Humans; Isoquinolines; Lamivudine; Nelfinavir; Pilot Projects; Reverse Transcriptase Inhibitors; Stavudine; Sulfonic Acids; Time Factors; Zidovudine | 1996 |
Reappraising d4T.
Topics: CD4 Lymphocyte Count; HIV; HIV Infections; Humans; Randomized Controlled Trials as Topic; Stavudine; Zidovudine | 1995 |
ACTG 343: (why) we can't relax our grip on viral suppression.
Topics: Anti-HIV Agents; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Reverse Transcriptase Inhibitors; Stavudine; Zidovudine | 1998 |
Persistence of zidovudine-resistance mutations in HIV-1 isolates from patients removed from zidovudine therapy for at least 3 years and switched to a stavudine-containing regimen.
Topics: Anti-HIV Agents; Drug Resistance, Microbial; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Point Mutation; Reverse Transcriptase Inhibitors; RNA, Viral; Stavudine; Viral Load; Zidovudine | 2001 |
Lactic acid levels in children perinatally treated with antiretroviral agents to prevent HIV transmission.
Topics: Anti-HIV Agents; Cross-Sectional Studies; Female; HIV Infections; HIV Protease Inhibitors; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Lactic Acid; Lamivudine; Male; Perinatal Care; Pregnancy; Pregnancy Complications, Infectious; Prenatal Care; Reverse Transcriptase Inhibitors; Stavudine; Zidovudine | 2001 |
Genotypic correlates of a virologic response to stavudine after zidovudine monotherapy.
Topics: Adult; Anti-HIV Agents; Drug Resistance, Microbial; Drug Resistance, Multiple; Female; Genotype; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Male; Mutation; Retrospective Studies; Reverse Transcriptase Inhibitors; Stavudine; Zidovudine | 2001 |
Comparison of genotypic and phenotypic resistance patterns of human immunodeficiency virus type 1 isolates from patients treated with stavudine and didanosine or zidovudine and lamivudine.
Topics: Adult; Didanosine; Dideoxynucleosides; Drug Resistance, Microbial; Drug Therapy, Combination; Female; Follow-Up Studies; Genotype; HIV Infections; HIV-1; Humans; Lamivudine; Male; Microbial Sensitivity Tests; Phenotype; Point Mutation; Reverse Transcriptase Inhibitors; Stavudine; Zidovudine | 2001 |
Failure of stavudine-lamivudine combination therapy in antiretroviral-naive patients with AZT-like HIV-1 resistance mutations.
Topics: Anti-HIV Agents; Cohort Studies; Drug Resistance, Viral; Drug Therapy, Combination; Genotype; HIV Infections; HIV Seropositivity; HIV-1; Humans; Lamivudine; Mutation; Stavudine; Treatment Failure; Zidovudine | 2001 |
Evidence of immune reconstitution in antiretroviral drug-experienced patients with advanced HIV disease.
Topics: Adult; Aged; Alkynes; Anti-HIV Agents; Antigens, CD; Antiretroviral Therapy, Highly Active; Benzoxazines; Biomarkers; CD4 Lymphocyte Count; CD8-Positive T-Lymphocytes; Cyclopropanes; Didanosine; Dideoxynucleosides; Double-Blind Method; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Indinavir; Lamivudine; Male; Middle Aged; Oxazines; Reverse Transcriptase Inhibitors; RNA, Viral; Stavudine; Treatment Outcome; Viral Load; Zidovudine | 2002 |
Efficacy of zidovudine compared to stavudine, both in combination with lamivudine and indinavir, in human immunodeficiency virus-infected nucleoside-experienced patients with no prior exposure to lamivudine, stavudine, or protease inhibitors (novavir tria
Topics: Adult; Anti-HIV Agents; Double-Blind Method; Drug Resistance, Microbial; Drug Therapy, Combination; Female; Follow-Up Studies; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Indinavir; Lamivudine; Male; Middle Aged; Reverse Transcriptase Inhibitors; RNA, Viral; Stavudine; Treatment Outcome; Viral Load; Zidovudine | 2002 |
Abacavir substitution for nucleoside analogs in patients with HIV lipoatrophy: a randomized trial.
Topics: Absorptiometry, Photon; Adult; Anti-HIV Agents; Body Composition; Dideoxynucleosides; Female; HIV Infections; Humans; Lipids; Lipodystrophy; Male; Middle Aged; Quality of Life; Reverse Transcriptase Inhibitors; Stavudine; Tomography, X-Ray Computed; Treatment Outcome; Viral Load; Zidovudine | 2002 |
A phase II randomized study of the virologic and immunologic effect of zidovudine + stavudine versus stavudine alone and zidovudine + lamivudine in patients with >300 CD4 cells who were antiretroviral naive (ACTG 298).
Topics: Acquired Immunodeficiency Syndrome; Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Lamivudine; Male; Middle Aged; RNA, Viral; Stavudine; Zidovudine | 2002 |
Subtle decreases in stavudine phenotypic susceptibility predict poor virologic response to stavudine monotherapy in zidovudine-experienced patients.
Topics: Adult; Anti-HIV Agents; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Microbial Sensitivity Tests; Mutation; Phenotype; Predictive Value of Tests; Reverse Transcriptase Inhibitors; RNA, Viral; Stavudine; Thymidine; Time Factors; Treatment Outcome; Viral Load; Zidovudine | 2002 |
Increased risk of lipoatrophy under stavudine in HIV-1-infected patients: results of a substudy from a comparative trial.
Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Body Constitution; Body Mass Index; Female; Follow-Up Studies; HIV Infections; HIV-Associated Lipodystrophy Syndrome; Humans; Indinavir; Lamivudine; Male; Middle Aged; Risk Factors; Stavudine; Zidovudine | 2002 |
Thymidine analogue withdrawal for lipoatrophic patients on protease-sparing therapy improves lipoatrophy but compromises antiviral control: the PIILR extension study.
Topics: Anti-HIV Agents; HIV-Associated Lipodystrophy Syndrome; Humans; Male; Middle Aged; Stavudine; Substance Withdrawal Syndrome; Thymidine; Zidovudine | 2002 |
Effect of zidovudine resistance mutations on virologic response to treatment with zidovudine or stavudine, each in combination with lamivudine and indinavir.
Topics: Anti-HIV Agents; Drug Administration Schedule; Drug Resistance, Viral; Drug Therapy, Combination; Female; Genotype; HIV; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Male; Mutation; Patient Compliance; RNA, Viral; Stavudine; Viral Load; Zidovudine | 2002 |
Randomized, controlled, 48-week study of switching stavudine and/or protease inhibitors to combivir/abacavir to prevent or reverse lipoatrophy in HIV-infected patients.
Topics: Adult; Body Composition; Dideoxynucleosides; Drug Combinations; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; HIV-Associated Lipodystrophy Syndrome; Humans; Lamivudine; Male; Middle Aged; Stavudine; Zidovudine | 2003 |
Hydroxyurea in combination with didanosine and stavudine in antiretroviral-experienced HIV-infected subjects with a review of the literature.
Topics: Adult; Anti-HIV Agents; Antineoplastic Agents; Antiretroviral Therapy, Highly Active; Didanosine; Drug Administration Schedule; Drug Therapy, Combination; Female; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Hydroxyurea; Male; Middle Aged; Reverse Transcriptase Inhibitors; RNA, Viral; Stavudine; Viral Load; Zidovudine | 2003 |
Nucleoside analogue mutations and Q151M in HIV-1 subtype A/E infection treated with nucleoside reverse transcriptase inhibitors.
Topics: Anti-HIV Agents; Didanosine; Drug Resistance, Multiple; Drug Resistance, Viral; Drug Therapy, Combination; Genotype; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Mutation; Reverse Transcriptase Inhibitors; Stavudine; Zidovudine | 2003 |
Mitochondrial proliferation, DNA depletion and adipocyte differentiation in subcutaneous adipose tissue of HIV-positive HAART recipients.
Topics: Adipocytes; Adipose Tissue; Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Cell Differentiation; Dideoxynucleosides; DNA, Mitochondrial; HIV Infections; HIV Protease Inhibitors; Humans; Male; Middle Aged; Mitochondria; Mitochondrial Proteins; Polymerase Chain Reaction; Reverse Transcriptase Inhibitors; RNA, Messenger; Stavudine; Zidovudine | 2003 |
Thymidine analogue mutations in antiretroviral-naive HIV-1 patients on triple therapy including either zidovudine or stavudine.
Topics: Adolescent; Adult; Aged; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Drug Resistance, Multiple, Viral; Female; Genotype; HIV Infections; HIV-1; Humans; Male; Middle Aged; Mutation; Stavudine; Thymidine; Viral Load; Zidovudine | 2004 |
Comparison of sequential three-drug regimens as initial therapy for HIV-1 infection.
Topics: Adult; Alkynes; Anti-Retroviral Agents; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; Didanosine; Double-Blind Method; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Middle Aged; Nelfinavir; Oxazines; RNA, Viral; Stavudine; Time Factors; Treatment Failure; Zidovudine | 2003 |
Comparison of four-drug regimens and pairs of sequential three-drug regimens as initial therapy for HIV-1 infection.
Topics: Adult; Alkynes; Anti-Retroviral Agents; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; Didanosine; Double-Blind Method; Drug Resistance, Viral; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Mutation; Nelfinavir; Oxazines; Stavudine; Time Factors; Treatment Failure; Zidovudine | 2003 |
Improvement in lipoatrophy associated with highly active antiretroviral therapy in human immunodeficiency virus-infected patients switched from stavudine to abacavir or zidovudine: the results of the TARHEEL study.
Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Dideoxynucleosides; Female; HIV; HIV Infections; HIV-1; Humans; Lipodystrophy; Male; Middle Aged; RNA, Viral; Stavudine; Treatment Outcome; Viral Load; Zidovudine | 2004 |
Reversibility of lipoatrophy in HIV-infected patients 2 years after switching from a thymidine analogue to abacavir: the MITOX Extension Study.
Topics: Absorptiometry, Photon; Adipose Tissue; Anti-HIV Agents; Body Composition; Bone Density; Dideoxynucleosides; Follow-Up Studies; HIV Infections; HIV-Associated Lipodystrophy Syndrome; Humans; Reverse Transcriptase Inhibitors; Stavudine; Zidovudine | 2004 |
Rate of thymidine analogue resistance mutation accumulation with zidovudine- or stavudine-based regimens.
Topics: Drug Resistance, Multiple, Viral; HIV Infections; HIV-1; Humans; Lamivudine; Molecular Sequence Data; Mutation; Reverse Transcriptase Inhibitors; Stavudine; Zidovudine | 2004 |
Pharmacokinetic characteristics of ritonavir, zidovudine, lamivudine, and stavudine in children with human immunodeficiency virus infection.
Topics: Adolescent; Anti-HIV Agents; Area Under Curve; Child; Child, Preschool; Drug Interactions; Drug Therapy, Combination; Female; Half-Life; HIV Infections; Humans; Lamivudine; Male; Metabolic Clearance Rate; Ritonavir; Stavudine; Zidovudine | 2004 |
Three-year durability of dual-nucleoside versus triple-nucleoside therapy in a Thai population with HIV infection.
Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Didanosine; Dideoxynucleosides; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Retrospective Studies; RNA, Viral; Stavudine; Thailand; Time Factors; Zidovudine | 2004 |
Lack of recurrence of hyperlactatemia in HIV-infected patients switched from stavudine to abacavir or zidovudine.
Topics: Adult; Anti-HIV Agents; Dideoxynucleosides; Female; HIV Infections; HIV-1; Humans; Lactates; Male; Middle Aged; Recurrence; Stavudine; Treatment Outcome; Viral Load; Zidovudine | 2004 |
Prevalence of lipoatrophy and mitochondrial DNA content of blood and subcutaneous fat in HIV-1-infected patients randomly allocated to zidovudine- or stavudine-based therapy.
Topics: Adipose Tissue; Adult; Anti-HIV Agents; DNA, Mitochondrial; Follow-Up Studies; HIV Infections; HIV-Associated Lipodystrophy Syndrome; Humans; Leukocytes, Mononuclear; Middle Aged; Muscle, Skeletal; Radiography; Reverse Transcriptase Inhibitors; Stavudine; Zidovudine | 2004 |
HIV-1 drug resistance in subjects with advanced HIV-1 infection in whom antiretroviral combination therapy is failing: a substudy of AIDS Clinical Trials Group Protocol 388.
Topics: Acquired Immunodeficiency Syndrome; Adult; Antiretroviral Therapy, Highly Active; Drug Resistance, Viral; Female; Genotype; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Indinavir; Lamivudine; Male; Nelfinavir; Phenotype; Stavudine; Treatment Failure; Zidovudine | 2004 |
Field assessment of generic antiretroviral drugs: a prospective cohort study in Cameroon.
Topics: Adult; Anti-HIV Agents; Cameroon; CD4 Lymphocyte Count; Cohort Studies; Drug Resistance, Viral; Drug Therapy, Combination; Drugs, Generic; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Nevirapine; Prospective Studies; Stavudine; Treatment Outcome; Viral Load; Zidovudine | 2005 |
Results of the ALBI trial: a randomized comparison of stavudine/didanosine, zidovudine/lamivudine and alternating treatment in antiretroviral-naive patients.
Topics: Anti-HIV Agents; Didanosine; Drug Administration Schedule; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Lamivudine; Reverse Transcriptase Inhibitors; RNA, Viral; Stavudine; Treatment Outcome; Viral Load; Zidovudine | 1999 |
Effect of ribavirin on intracellular and plasma pharmacokinetics of nucleoside reverse transcriptase inhibitors in patients with human immunodeficiency virus-hepatitis C virus coinfection: results of a randomized clinical study.
Topics: Adult; Area Under Curve; Drug Therapy, Combination; Female; Hepacivirus; Hepatitis C; HIV Infections; HIV-1; Humans; Interferon alpha-2; Interferon-alpha; Lamivudine; Male; Middle Aged; Polyethylene Glycols; Recombinant Proteins; Reverse Transcriptase Inhibitors; Ribavirin; Stavudine; Time Factors; Zidovudine | 2005 |
Brain mitochondrial injury in human immunodeficiency virus-seropositive (HIV+) individuals taking nucleoside reverse transcriptase inhibitors.
Topics: Adult; Aspartic Acid; Brain; Cell Respiration; Didanosine; Female; HIV Infections; Humans; Lamivudine; Magnetic Resonance Spectroscopy; Male; Middle Aged; Mitochondria; Mitochondrial Diseases; Reverse Transcriptase Inhibitors; Stavudine; Treatment Outcome; Zidovudine | 2005 |
A prospective, 96-week study of the impact of Trizivir, Combivir/nelfinavir, and lamivudine/stavudine/nelfinavir on lipids, metabolic parameters and efficacy in antiretroviral-naive patients: effect of sex and ethnicity.
Topics: Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Black or African American; CD4 Lymphocyte Count; Cholesterol; Dideoxynucleosides; Drug Combinations; Female; Hispanic or Latino; HIV Infections; HIV-1; Humans; Hyperlipidemias; Lactic Acid; Lamivudine; Male; Nelfinavir; Nevirapine; Prospective Studies; Sex Factors; Stavudine; Treatment Outcome; Triglycerides; Zidovudine | 2006 |
[Clinical trial comparing efficacy and safety of four highly active antiretroviral therapy (HAART) in antiretroviral-naive treatment with advanced HIV infection].
Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Didanosine; Disease Progression; Female; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Male; Middle Aged; Ritonavir; Stavudine; Zidovudine | 2006 |
Antiviral activity of nucleoside analogues during short-course monotherapy or dual therapy: its role in preventing HIV infection in infants.
Topics: Acidosis, Lactic; Anti-HIV Agents; CD4 Lymphocyte Count; Didanosine; Drug Therapy, Combination; Fatty Liver; Female; HIV Infections; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Male; Mothers; Pregnancy; Pregnancy Complications, Infectious; Prospective Studies; RNA, Viral; South Africa; Stavudine; Viral Load; Zidovudine | 2006 |
A randomized comparative trial of tenofovir DF or abacavir as replacement for a thymidine analogue in persons with lipoatrophy.
Topics: Adenine; Adult; Aged; Anti-HIV Agents; Biomarkers; Body Fat Distribution; Dideoxynucleosides; Female; HIV Infections; HIV-Associated Lipodystrophy Syndrome; Humans; Lipids; Male; Middle Aged; Organophosphonates; Reverse Transcriptase Inhibitors; Stavudine; Tenofovir; Zidovudine | 2006 |
Triple antiretroviral prophylaxis administered during pregnancy and after delivery significantly reduces breast milk viral load: a study within the Drug Resource Enhancement Against AIDS and Malnutrition Program.
Topics: Adolescent; Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Female; HIV; HIV Infections; Humans; Lamivudine; Milk, Human; Nevirapine; Pilot Projects; Pregnancy; Pregnancy Complications, Infectious; Pregnancy Trimester, Third; RNA, Viral; Stavudine; Zidovudine | 2007 |
Changes in the peripheral blood mtDNA levels in naive patients treated by different nucleoside reverse transcriptase inhibitor combinations and their association with subsequent lipodystrophy.
Topics: Adult; Anti-HIV Agents; Didanosine; DNA, Mitochondrial; Drug Therapy, Combination; Female; Follow-Up Studies; HIV Infections; HIV-Associated Lipodystrophy Syndrome; Humans; Lamivudine; Leukocytes, Mononuclear; Logistic Models; Male; Reverse Transcriptase Inhibitors; Stavudine; Surveys and Questionnaires; Time Factors; Zidovudine | 2007 |
Pharmacokinetic evaluation of emtricitabine in combination with other nucleoside antivirals in healthy volunteers.
Topics: 2-Aminopurine; Adolescent; Adult; Anti-HIV Agents; Area Under Curve; Cross-Over Studies; Deoxycytidine; Drug Interactions; Drug Therapy, Combination; Emtricitabine; Famciclovir; Female; Humans; Male; Middle Aged; Reverse Transcriptase Inhibitors; Stavudine; Zidovudine | 2007 |
Effects of potent antiretroviral therapy on free testosterone levels and fat-free mass in men in a prospective, randomized trial: A5005s, a substudy of AIDS Clinical Trials Group Study 384.
Topics: Adult; Anti-HIV Agents; Anti-Retroviral Agents; Didanosine; Double-Blind Method; HIV Infections; Humans; Lamivudine; Longitudinal Studies; Male; Nelfinavir; Prospective Studies; Stavudine; Testosterone; Zidovudine | 2007 |
Long-term body fat outcomes in antiretroviral-naive participants randomized to nelfinavir or efavirenz or both plus dual nucleosides. Dual X-ray absorptiometry results from A5005s, a substudy of Adult Clinical Trials Group 384.
Topics: Absorptiometry, Photon; Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Body Composition; Cyclopropanes; Didanosine; Drug Therapy, Combination; Female; HIV; HIV Infections; HIV Protease Inhibitors; HIV-Associated Lipodystrophy Syndrome; Humans; Lamivudine; Male; Middle Aged; Nelfinavir; Prospective Studies; Stavudine; Time Factors; Treatment Outcome; United States; Zidovudine | 2007 |
Population pharmacokinetic analysis of lamivudine, stavudine and zidovudine in controlled HIV-infected patients on HAART.
Topics: Adult; Aged; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Drug Interactions; Female; HIV Infections; Humans; Indinavir; Lamivudine; Male; Middle Aged; Models, Biological; Nelfinavir; Reverse Transcriptase Inhibitors; Stavudine; Tissue Distribution; Zidovudine | 2007 |
Tolerability and effectiveness of first-line regimens combining nevirapine and lamivudine plus zidovudine or stavudine in Cameroon.
Topics: Adult; Anemia; Anti-HIV Agents; Cameroon; CD4 Lymphocyte Count; Cohort Studies; Drug Therapy, Combination; Female; Follow-Up Studies; HIV Infections; HIV-Associated Lipodystrophy Syndrome; Humans; Kaplan-Meier Estimate; Lamivudine; Male; Multivariate Analysis; Nevirapine; Patient Compliance; Peripheral Nervous System Diseases; Prospective Studies; Stavudine; Treatment Outcome; Viral Load; Zidovudine | 2008 |
Long-term subcutaneous tissue changes among antiretroviral-naive persons initiating stavudine, zidovudine, or abacavir with lamivudine.
Topics: Adult; Cohort Studies; Dideoxynucleosides; Female; HIV Infections; Humans; Lamivudine; Male; Middle Aged; Reverse Transcriptase Inhibitors; Stavudine; Subcutaneous Fat; Zidovudine | 2008 |
Changes in antioxidant profile among HIV-infected individuals on generic highly active antiretroviral therapy in southern India.
Topics: Adult; Albumins; Alkynes; Anti-HIV Agents; Antioxidants; Antiretroviral Therapy, Highly Active; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; Drug Therapy, Combination; Drugs, Generic; Female; Glutathione Peroxidase; Glutathione Reductase; HIV Infections; Humans; India; Lamivudine; Male; Oxidative Stress; Reverse Transcriptase Inhibitors; Stavudine; Uric Acid; Young Adult; Zidovudine | 2008 |
Endothelial function in human immunodeficiency virus-infected antiretroviral-naive subjects before and after starting potent antiretroviral therapy: The ACTG (AIDS Clinical Trials Group) Study 5152s.
Topics: Adenine; Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Brachial Artery; CD4 Lymphocyte Count; Cyclopropanes; Endothelium, Vascular; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Lopinavir; Male; Organophosphonates; Prospective Studies; Pyrimidinones; Reverse Transcriptase Inhibitors; Ritonavir; Stavudine; Tenofovir; Time Factors; Zidovudine | 2008 |
The 3-year renal safety of a tenofovir disoproxil fumarate vs. a thymidine analogue-containing regimen in antiretroviral-naive patients.
Topics: Adenine; Adolescent; Adult; Aged; Aged, 80 and over; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Creatinine; Double-Blind Method; Female; Glomerular Filtration Rate; HIV Infections; HIV-1; Humans; Male; Middle Aged; Organophosphonates; Phosphorus; Proteinuria; Reverse Transcriptase Inhibitors; Stavudine; Tenofovir; Young Adult; Zidovudine | 2008 |
Peripheral and visceral fat changes following a treatment switch to a non-thymidine analogue or a nucleoside-sparing regimen in HIV-infected subjects with peripheral lipoatrophy: results of ACTG A5110.
Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Dideoxynucleosides; Female; HIV Infections; HIV-Associated Lipodystrophy Syndrome; Humans; Intra-Abdominal Fat; Lopinavir; Male; Middle Aged; Nevirapine; Pyrimidinones; Radiography, Abdominal; Stavudine; Thigh; Viral Load; Zidovudine | 2009 |
Improvements in cheek volume in lipoatrophic individuals switching away from thymidine nucleoside reverse transcriptase inhibitors.
Topics: Absorptiometry, Photon; Adenine; Adult; Aged; Body Composition; Cheek; Dideoxynucleosides; Female; HIV Infections; HIV-1; HIV-Associated Lipodystrophy Syndrome; Humans; Male; Middle Aged; Organophosphonates; Quality of Life; Reverse Transcriptase Inhibitors; Stavudine; Tenofovir; Zidovudine | 2009 |
Interindividual variability in pharmacokinetics of generic nucleoside reverse transcriptase inhibitors in TB/HIV-coinfected Ghanaian patients: UGT2B7*1c is associated with faster zidovudine clearance and glucuronidation.
Topics: Adult; AIDS-Related Opportunistic Infections; Drug Combinations; Drug Therapy, Combination; Drugs, Generic; Female; Ghana; Glucuronides; Glucuronosyltransferase; Half-Life; HIV Infections; Humans; Lamivudine; Liver; Male; Middle Aged; Polymorphism, Genetic; Reverse Transcriptase Inhibitors; Stavudine; Tuberculosis; Zidovudine | 2009 |
Rates of virological failure in patients treated in a home-based versus a facility-based HIV-care model in Jinja, southeast Uganda: a cluster-randomised equivalence trial.
Topics: Adenine; Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Community Health Services; Female; HIV; HIV Infections; Home Care Services; Humans; Lamivudine; Male; Nevirapine; Organophosphonates; Stavudine; Tenofovir; Uganda; Zidovudine | 2009 |
A randomized factorial trial comparing 4 treatment regimens in treatment-naive HIV-infected persons with AIDS and/or a CD4 cell count <200 cells/μL in South Africa.
Topics: Acquired Immunodeficiency Syndrome; Adult; Alkynes; Anti-HIV Agents; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; Didanosine; Drug Therapy, Combination; Female; HIV; Humans; Lamivudine; Lopinavir; Male; Pyrimidinones; Ritonavir; RNA, Viral; South Africa; Stavudine; Treatment Outcome; Zidovudine | 2010 |
Randomized trial of time-limited interruptions of protease inhibitor-based antiretroviral therapy (ART) vs. continuous therapy for HIV-1 infection.
Topics: Anti-HIV Agents; CD4-Positive T-Lymphocytes; HIV Infections; Lamivudine; Lopinavir; Protease Inhibitors; Ritonavir; Stavudine; Zidovudine | 2011 |
A 72-week randomized study of the safety and efficacy of a stavudine to zidovudine switch at 24 weeks compared to zidovudine or tenofovir disoproxil fumarate when given with lamivudine and nevirapine.
Topics: Adenine; Adult; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Diet; Drug Administration Schedule; Drug Substitution; Female; Glomerular Filtration Rate; Hemoglobins; HIV Infections; Humans; Lamivudine; Male; Nevirapine; Organophosphonates; Peripheral Nervous System Diseases; Stavudine; Tenofovir; Treatment Outcome; Viral Load; Zidovudine | 2012 |
Increased risk of Q151M and K65R mutations in patients failing stavudine-containing first-line antiretroviral therapy in Cambodia.
Topics: Acquired Immunodeficiency Syndrome; Adolescent; Adult; Amino Acid Substitution; Anti-HIV Agents; Base Sequence; Cambodia; Child; Child, Preschool; Drug Resistance, Multiple, Viral; Female; Follow-Up Studies; HIV Reverse Transcriptase; HIV-1; Humans; Male; Molecular Sequence Data; Mutation, Missense; Retrospective Studies; Stavudine; Zidovudine | 2013 |
Anthropometric measurements and lipid profiles to detect early lipodystrophy in antiretroviral therapy experienced HIV-infected children in the CHAPAS-3 trial.
Topics: Anthropometry; Anti-HIV Agents; Child; Child, Preschool; Cross-Sectional Studies; Dideoxynucleosides; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Lamivudine; Lipid Metabolism; Lipodystrophy; Lipoproteins, HDL; Lipoproteins, LDL; Male; Nevirapine; Stavudine; Triglycerides; Viral Load; Zidovudine | 2014 |
Prevalence, incidence and predictors of peripheral neuropathy in African adults with HIV infection within the DART trial.
Topics: Adolescent; Adult; Aged; Anti-Retroviral Agents; Antitubercular Agents; Didanosine; Female; HIV Infections; Humans; Incidence; Isoniazid; Male; Middle Aged; Peripheral Nervous System Diseases; Prevalence; Risk Factors; Stavudine; Uganda; Young Adult; Zidovudine; Zimbabwe | 2014 |
A randomized, open-label study of the safety and efficacy of switching stavudine or zidovudine to tenofovir disoproxil fumarate in HIV-1-infected children with virologic suppression.
Topics: Adenine; Adolescent; Anti-HIV Agents; Child; Child, Preschool; Drug-Related Side Effects and Adverse Reactions; Female; HIV Infections; HIV-1; Humans; Male; Organophosphonates; RNA, Viral; Stavudine; Tenofovir; Treatment Outcome; Viral Load; Zidovudine | 2015 |
Distal leg epidermal nerve fiber density as a surrogate marker of HIV-associated sensory neuropathy risk: risk factors and change following initial antiretroviral therapy.
Topics: Adult; Anti-Retroviral Agents; Cross-Sectional Studies; Female; HIV Infections; Humans; Leg; Male; Peripheral Nervous System Diseases; Risk Factors; Sensory Receptor Cells; Skin; Stavudine; Tenofovir; Thailand; Zidovudine | 2015 |
Abacavir, zidovudine, or stavudine as paediatric tablets for African HIV-infected children (CHAPAS-3): an open-label, parallel-group, randomised controlled trial.
Topics: Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Child; Child, Preschool; Cyclopropanes; Dideoxynucleosides; Drug Therapy, Combination; Female; HIV Infections; Humans; Infant; Lamivudine; Male; Nevirapine; Stavudine; Tablets; Uganda; Zambia; Zidovudine | 2016 |
In vitro-in vivo Pharmacokinetic correlation model for quality assurance of antiretroviral drugs.
Topics: Adolescent; Adult; Animals; Anti-HIV Agents; Area Under Curve; Biological Availability; Caco-2 Cells; Humans; Lamivudine; Male; Models, Biological; Permeability; Rabbits; Solubility; Species Specificity; Stavudine; Young Adult; Zidovudine | 2015 |
The association between HIV tri-therapy with the development of Type-2 Diabetes Mellitus in a rural South African District: A case-control study.
Topics: Adult; Diabetes Mellitus, Type 2; Female; HIV Infections; Humans; Male; Middle Aged; Prospective Studies; Rural Population; South Africa; Stavudine; Time Factors; Zidovudine | 2020 |
462 other study(ies) available for zidovudine and stavudine
| Article | Year |
|---|---|
Synthesis and in vitro evaluation of some modified 4-thiopyrimidine nucleosides for prevention or reversal of AIDS-associated neurological disorders.
Topics: AIDS Dementia Complex; Animals; Antiviral Agents; Cell Line; Chemical Phenomena; Chemistry; Chemistry, Physical; Cytopathogenic Effect, Viral; Dideoxynucleosides; HIV; Humans; Kinetics; Molecular Structure; Phosphorylation; Pyrimidine Nucleosides; Rabbits; Stavudine; T-Lymphocytes; Thymidine Kinase; Thymus Gland; Zidovudine | 1990 |
Synthesis and anti-HIV evaluation of 2',3'-dideoxyribo-5-chloropyrimidine analogues: reduced toxicity of 5-chlorinated 2',3'-dideoxynucleosides.
Topics: Antiviral Agents; Cell Line; Dideoxynucleosides; HIV; Humans; Molecular Conformation; X-Ray Diffraction | 1990 |
1-(2,3-Dideoxy-beta-D-glycero-pent-2-enofuranosyl)thymine. A highly potent and selective anti-HIV agent.
Topics: Antiviral Agents; Bone Marrow; Dideoxynucleosides; HIV; Stavudine; Thymidine; Zidovudine | 1989 |
Structure-activity relationships of pyrimidine nucleosides as antiviral agents for human immunodeficiency virus type 1 in peripheral blood mononuclear cells.
Topics: Antiviral Agents; Cell Division; Chemical Phenomena; Chemistry; HIV-1; Humans; Leukocytes, Mononuclear; Pyrimidine Nucleosides; Structure-Activity Relationship | 1989 |
1-(3-cyano-2,3-dideoxy-beta-D-erythro-pentofuranosyl)thymine (cyanothymidine): synthesis and antiviral evaluation against human immunodeficiency virus.
Topics: Antiviral Agents; Chemical Phenomena; Chemistry; HIV-1; Humans; Models, Molecular; Stereoisomerism; Structure-Activity Relationship; Thymidine; X-Ray Diffraction | 1989 |
3'-substituted 2',3'-dideoxynucleoside analogues as potential anti-HIV (HTLV-III/LAV) agents.
Topics: Antiviral Agents; Cell Line; Chemical Phenomena; Chemistry; Cytopathogenic Effect, Viral; Deoxyribonucleosides; HIV; Humans; Structure-Activity Relationship; T-Lymphocytes; Virus Replication | 1987 |
Synthesis and antiviral activity of various 3'-azido, 3'-amino, 2',3'-unsaturated, and 2',3'-dideoxy analogues of pyrimidine deoxyribonucleosides against retroviruses.
Topics: Antiviral Agents; Cell Line; HIV; Indicators and Reagents; Magnetic Resonance Spectroscopy; Moloney murine leukemia virus; Pyrimidine Nucleosides; Spectrophotometry; Structure-Activity Relationship | 1987 |
HIV-1 reverse transcriptase inhibitor design using artificial neural networks.
Topics: Algorithms; Cell Line; Drug Design; HIV Reverse Transcriptase; HIV-1; Humans; Molecular Structure; Neural Networks, Computer; Pyrimidines; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; T-Lymphocytes; Zidovudine | 1994 |
Synthesis and anti-HIV evaluation of D4T and D4T 5'-monophosphate prodrugs.
Topics: Antiviral Agents; Cell Line; Dideoxynucleosides; Dideoxynucleotides; HIV-1; Humans; Prodrugs; Stavudine; Structure-Activity Relationship; Thymine Nucleotides; Tumor Cells, Cultured; Virus Replication | 1993 |
Aryl phosphoramidate derivatives of d4T have improved anti-HIV efficacy in tissue culture and may act by the generation of a novel intracellular metabolite.
Topics: 3T3 Cells; Animals; Antiviral Agents; HIV; Mice; Phosphates; Stavudine; Structure-Activity Relationship | 1996 |
cycloSal-2',3'-dideoxy-2',3'-didehydrothymidine monophosphate (cycloSal-d4TMP): synthesis and antiviral evaluation of a new d4TMP delivery system.
Topics: Animals; Anti-HIV Agents; Buffers; Cattle; Chromatography, High Pressure Liquid; Drug Delivery Systems; HIV-1; HIV-2; Humans; Hydrogen-Ion Concentration; Hydrolysis; Mutation; Octanols; Organophosphates; Prodrugs; Solubility; Stavudine; Stereoisomerism; Structure-Activity Relationship; T-Lymphocytes; Thymidine Kinase; Thymidine Monophosphate; Tumor Cells, Cultured | 1998 |
Enhancing effects of a mono-bromo substitution at the para position of the phenyl moiety on the metabolism and anti-HIV activity of d4T-phenyl methoxyalaninyl phosphate derivatives.
Topics: Anti-HIV Agents; Humans; Stavudine; Structure-Activity Relationship; Zidovudine | 1998 |
cycloSal-Pronucleotides of 2',3'-dideoxyadenosine and 2', 3'-dideoxy-2',3'-didehydroadenosine: synthesis and antiviral evaluation of a highly efficient nucleotide delivery system.
Topics: 3T3 Cells; Adenosine Deaminase; Adenosine Monophosphate; AMP Deaminase; Animals; Anti-HIV Agents; Cell Line; Cell Transformation, Viral; Deoxyadenine Nucleotides; Dideoxynucleotides; Drug Delivery Systems; Drug Evaluation, Preclinical; HIV-1; HIV-2; Humans; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Mice; Organophosphates; Prodrugs; Structure-Activity Relationship; Virus Replication | 1999 |
cycloSal-Pronucleotides of 2'-fluoro-ara- and 2'-fluoro-ribo-2',3'- dideoxyadenosine as a strategy to bypass a metabolic blockade.
Topics: 3T3 Cells; Adenosine Deaminase; AMP Deaminase; Animals; Anti-HIV Agents; Cell Line; Dideoxyadenosine; Drug Delivery Systems; HIV-1; HIV-2; Humans; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Mice; Organophosphates; Prodrugs; Structure-Activity Relationship; Virus Replication | 1999 |
Rat multispecific organic anion transporter 1 (rOAT1) transports zidovudine, acyclovir, and other antiviral nucleoside analogs.
Topics: Acyclovir; Animals; Anion Transport Proteins; Antiviral Agents; Carrier Proteins; Didanosine; In Vitro Techniques; Lamivudine; Oocytes; Rats; Stavudine; Transfection; Trifluridine; Xenopus laevis; Zalcitabine; Zidovudine | 2000 |
Carbocyclic dinucleoside polyphosphonates: interaction with HIV reverse transcriptase and antiviral activity.
Topics: Animals; Anti-HIV Agents; Cells, Cultured; Cyclopentanes; HIV Reverse Transcriptase; Humans; Liposomes; Nucleosides; Organophosphorus Compounds; Rats; Reverse Transcriptase Inhibitors; Structure-Activity Relationship | 2002 |
A conformationally locked analogue of the anti-HIV agent stavudine. An important correlation between pseudorotation and maximum amplitude.
Topics: Animals; Anti-HIV Agents; Bridged Bicyclo Compounds; Cell Line; Crystallography, X-Ray; HIV Reverse Transcriptase; HIV-1; HIV-2; Humans; Lymphocytes; Molecular Conformation; Molecular Mimicry; Reverse Transcriptase Inhibitors; Stavudine; Stereoisomerism; Structure-Activity Relationship; Thymidine | 2003 |
2('),3(')-didehydro-2('),3(')-dideoxynucleosides are degraded to furfuryl alcohol under acidic conditions.
Topics: Acids; Animals; Cell Line; Dideoxynucleosides; Furans; Humans; Magnetic Resonance Spectroscopy | 2004 |
Uncharged AZT and D4T derivatives of phosphonoformic and phosphonoacetic acids as anti-HIV pronucleosides.
Topics: Anti-HIV Agents; Cell Line; Drug Stability; Foscarnet; HIV-1; Humans; Hydrolysis; Phosphonoacetic Acid; Prodrugs; Stavudine; Stereoisomerism; Structure-Activity Relationship; Zidovudine | 2004 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Synthesis, in vitro antiviral evaluation, and stability studies of novel alpha-borano-nucleotide analogues of 9-[2-(phosphonomethoxy)ethyl]adenine and (R)-9-[2-(phosphonomethoxy)propyl]adenine.
Topics: Adenine; Animals; Anti-HIV Agents; Antiviral Agents; Boranes; Boron Compounds; Chlorocebus aethiops; DNA Viruses; HIV-1; Humans; In Vitro Techniques; Nucleosides; Organophosphonates; Phosphates; RNA Viruses; Structure-Activity Relationship; Vero Cells; Virus Replication | 2006 |
Selective inhibition of porcine endogenous retrovirus replication in human cells by acyclic nucleoside phosphonates.
Topics: Adenine; Amino Acid Sequence; Animals; Antiviral Agents; Catalysis; Cell Line; Dose-Response Relationship, Drug; Endogenous Retroviruses; HIV-1; Humans; Kidney; Molecular Sequence Data; Organophosphonates; Polymerase Chain Reaction; Protein Structure, Tertiary; Reverse Transcriptase Inhibitors; Stavudine; Swine; Swine, Miniature; Tenofovir; Virus Replication; Zidovudine | 2007 |
Pharmacokinetics of the anti-human immunodeficiency virus agent 1-(beta-D-dioxolane)thymine in rhesus monkeys.
Topics: Administration, Oral; Animals; Antiviral Agents; Area Under Curve; Calibration; Chromatography, High Pressure Liquid; Dioxolanes; Female; Half-Life; HIV-1; Injections, Intravenous; Macaca mulatta; Mass Spectrometry; Metabolic Clearance Rate; Molecular Structure; Reference Standards; Reproducibility of Results; Thymine | 2007 |
Synthesis, anti-HIV activity, and resistance profile of thymidine phosphonomethoxy nucleosides and their bis-isopropyloxymethylcarbonyl (bisPOC) prodrugs.
Topics: Anti-HIV Agents; Cell Line; Drug Resistance, Viral; Magnetic Resonance Spectroscopy; Methane; Molecular Structure; Nucleosides; Organophosphorus Compounds; Prodrugs; Thymidine | 2007 |
Intracellular metabolism and persistence of the anti-human immunodeficiency virus activity of 2',3'-didehydro-3'-deoxy-4'-ethynylthymidine, a novel thymidine analog.
Topics: Anti-HIV Agents; Cell Line; Dideoxynucleotides; Dose-Response Relationship, Drug; HeLa Cells; HIV; Humans; Phosphorylation; Reverse Transcriptase Inhibitors; Stavudine; Thymine Nucleotides; Virus Replication; Zidovudine | 2007 |
Hologram QSAR model for the prediction of human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2007 |
Novel drug resistance pattern associated with the mutations K70G and M184V in human immunodeficiency virus type 1 reverse transcriptase.
Topics: Adenine; Amino Acid Substitution; Deoxycytidine; Didanosine; Dideoxynucleosides; Drug Resistance, Multiple, Viral; Emtricitabine; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Molecular Sequence Data; Mutation; Organophosphonates; Reverse Transcriptase Inhibitors; Stavudine; Tenofovir; Zidovudine | 2007 |
Human immunodeficiency virus types 1 and 2 exhibit comparable sensitivities to Zidovudine and other nucleoside analog inhibitors in vitro.
Topics: Anti-HIV Agents; HeLa Cells; HIV-1; HIV-2; Humans; Microbial Sensitivity Tests; Reverse Transcriptase Inhibitors; Zidovudine | 2008 |
Anti-BK virus activity of nucleoside analogs.
Topics: Adenine; BK Virus; Esters; Fatty Acids; Humans; Microbial Sensitivity Tests; Nucleosides; Organophosphonates; Virus Replication | 2008 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Impact of nucleoside reverse transcriptase inhibitors on mitochondrial DNA and RNA in human skeletal muscle cells.
Topics: Cell Proliferation; Cells, Cultured; Dideoxynucleosides; DNA, Mitochondrial; Humans; Lamivudine; Muscle Fibers, Skeletal; Muscle, Skeletal; Myoblasts; Nucleosides; Reverse Transcriptase Inhibitors; Reverse Transcriptase Polymerase Chain Reaction; RNA; RNA, Mitochondrial; Stavudine; Zidovudine | 2008 |
Effects of zidovudine and stavudine on mitochondrial DNA of differentiating 3T3-F442a cells are not associated with imbalanced deoxynucleotide pools.
Topics: 3T3 Cells; Animals; Anti-HIV Agents; Cell Differentiation; Deoxyribonucleotides; DNA, Mitochondrial; Dose-Response Relationship, Drug; Kinetics; Mice; Stavudine; Zidovudine | 2009 |
Unified QSAR approach to antimicrobials. 4. Multi-target QSAR modeling and comparative multi-distance study of the giant components of antiviral drug-drug complex networks.
Topics: Anti-Infective Agents; Antiviral Agents; Artificial Intelligence; Computer Simulation; Drug Evaluation, Preclinical; Molecular Structure; Quantitative Structure-Activity Relationship | 2009 |
Human immunodeficiency virus type 1 isolates with the reverse transcriptase (RT) mutation Q145M retain nucleoside and nonnucleoside RT inhibitor susceptibility.
Topics: Amino Acid Sequence; Anti-HIV Agents; Drug Resistance, Viral; Genotype; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Microbial Sensitivity Tests; Molecular Sequence Data; Mutation; Nucleosides; Phenotype; Reverse Transcriptase Inhibitors | 2009 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Anti-human immunodeficiency virus activity, cross-resistance, cytotoxicity, and intracellular pharmacology of the 3'-azido-2',3'-dideoxypurine nucleosides.
Topics: Anti-HIV Agents; Cell Line, Tumor; Cell Survival; Cells, Cultured; Dideoxynucleosides; HIV Infections; HIV-1; Humans; Molecular Structure; Reverse Transcriptase Inhibitors | 2009 |
Impact of novel human immunodeficiency virus type 1 reverse transcriptase mutations P119S and T165A on 4'-ethynylthymidine analog resistance profile.
Topics: Anti-HIV Agents; Computer Simulation; Drug Resistance, Viral; HIV Reverse Transcriptase; HIV-1; Humans; Microbial Sensitivity Tests; Mutation; Reverse Transcriptase Inhibitors; Stavudine | 2009 |
Mitochondrial DNA depletion and respiratory chain activity in primary human subcutaneous adipocytes treated with nucleoside analogue reverse transcriptase inhibitors.
Topics: Adipocytes; Azo Compounds; Cell Survival; Cells, Cultured; Coloring Agents; DNA, Mitochondrial; Electron Transport; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Glycerides; Humans; Reverse Transcriptase Inhibitors; Reverse Transcriptase Polymerase Chain Reaction; RNA; Skin | 2010 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2010 |
Synthesis of fluorescent nucleoside analogs as probes for 2'-deoxyribonucleoside kinases.
Topics: Animals; Drosophila melanogaster; Fluorescent Dyes; Nucleosides; Phosphotransferases (Alcohol Group Acceptor) | 2010 |
Development of hexadecyloxypropyl tenofovir (CMX157) for treatment of infection caused by wild-type and nucleoside/nucleotide-resistant HIV.
Topics: Adenine; Anti-HIV Agents; Cell Survival; Cells, Cultured; Drug Resistance, Viral; HIV Infections; HIV-1; Humans; Macrophages; Nucleosides; Nucleotides; Organophosphonates; Tenofovir | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
Predicting phospholipidosis using machine learning.
Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Design, synthesis and biological evaluation of phosphorodiamidate prodrugs of antiviral and anticancer nucleosides.
Topics: Anti-HIV Agents; Antineoplastic Agents; Caco-2 Cells; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; HeLa Cells; HIV-1; HIV-2; Humans; Microbial Sensitivity Tests; Molecular Structure; Nucleosides; Prodrugs; Structure-Activity Relationship | 2013 |
Hydroxy fatty acids for the delivery of dideoxynucleosides as anti-HIV agents.
Topics: Adenine; Anti-HIV Agents; Antiviral Agents; Dideoxynucleosides; Drug Delivery Systems; Fatty Acids; HIV-1; Humans; Hydroxy Acids; Molecular Structure; Prodrugs | 2014 |
Ionic derivatives of betulinic acid exhibit antiviral activity against herpes simplex virus type-2 (HSV-2), but not HIV-1 reverse transcriptase.
Topics: Acyclovir; Animals; Antiviral Agents; Betulinic Acid; Chlorocebus aethiops; Herpesvirus 2, Human; HIV Reverse Transcriptase; HIV-1; Humans; Pentacyclic Triterpenes; Triterpenes; Vero Cells; Virus Replication | 2015 |
Nucleoside Diphosphate Prodrugs: Nonsymmetric DiPPro-Nucleotides.
Topics: Anti-HIV Agents; Cell Line; Chromatography, High Pressure Liquid; HIV-1; HIV-2; Humans; Nucleosides; Nucleotides; Prodrugs | 2015 |
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone | 2016 |
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries | 2023 |
In vitro toxicity of 3'-azido-3'-deoxythymidine, carbovir and 2',3'-didehydro-2',3'-dideoxythymidine to human and murine haematopoietic progenitor cells.
Topics: Animals; Antiviral Agents; Bone Marrow Cells; Cell Division; Cells, Cultured; Colony-Forming Units Assay; Dideoxynucleosides; Dose-Response Relationship, Drug; Hematopoietic Stem Cells; Humans; In Vitro Techniques; Mice; Mice, Inbred Strains; Stavudine; Zidovudine | 1992 |
[Synthesis of nucleoside 5'-fluoroalkylphosphonate--compounds with potential antiviral properties].
Topics: Antiviral Agents; Dideoxynucleosides; Magnetic Resonance Spectroscopy; Organophosphorus Compounds; Stavudine; Zidovudine | 1992 |
Synthesis of 5-homologous AZT and D4T derivatives.
Topics: Antiviral Agents; Dideoxynucleosides; Stavudine; Zidovudine | 1992 |
Suppression of murine retroviral disease by 2',3'-didehydro-2',3'-dideoxythymidine (D4T).
Topics: Animals; Antibodies, Viral; Antiviral Agents; Cell Line; Dideoxynucleosides; Drug Administration Schedule; Female; Friend murine leukemia virus; Killer Cells, Natural; Leukemia, Experimental; Male; Mice; Stavudine; Zidovudine | 1992 |
The PC12 cell as a model for studies of the mechanism of induction of peripheral neuropathy by anti-HIV-1 dideoxynucleoside analogs.
Topics: Animals; Axons; Bone Marrow; Cell Division; Cell Line, Transformed; Didanosine; Dideoxynucleosides; Dose-Response Relationship, Drug; Peripheral Nervous System Diseases; Stavudine; Tumor Cells, Cultured; Zalcitabine; Zidovudine | 1991 |
Metabolism and DNA interaction of 2',3'-didehydro-2',3'-dideoxythymidine in human bone marrow cells.
Topics: Antiviral Agents; Bone Marrow; Dideoxynucleosides; DNA; Drug Stability; Humans; In Vitro Techniques; Stavudine; Zidovudine | 1991 |
Comparison of in vitro biological properties and mouse toxicities of three thymidine analogs active against human immunodeficiency virus.
Topics: Administration, Oral; Animals; Antiviral Agents; Bone Marrow; Dideoxynucleosides; HIV-1; Leukemia, Experimental; Male; Mice; Microbial Sensitivity Tests; Retroviridae; Reverse Transcriptase Inhibitors; Stavudine; Zidovudine | 1990 |
Development and application of an in vitro model for screening anti-hepatitis B virus therapeutics.
Topics: Antiviral Agents; Dideoxynucleosides; DNA Replication; DNA, Viral; Hepatitis B; Hepatitis B virus; Humans; In Vitro Techniques; Interferon Type I; Stavudine; Vidarabine; Vidarabine Phosphate; Virus Replication; Zalcitabine; Zidovudine | 1991 |
Effect of anti-human immunodeficiency virus nucleoside analogs on mitochondrial DNA and its implication for delayed toxicity.
Topics: Antiviral Agents; Cell Line; Cytarabine; Didanosine; Dideoxynucleosides; DNA, Mitochondrial; HIV; Humans; Lymphocyte Activation; Nucleosides; Stavudine; T-Lymphocytes; Zalcitabine; Zidovudine | 1991 |
Potent and selective in vitro activity of 3'-deoxythymidin-2'-ene (3'-deoxy-2',3'-didehydrothymidine) against human immunodeficiency virus.
Topics: Antiviral Agents; Deoxycytidine; HIV; Humans; Monocytes; Retroviridae Proteins; RNA-Directed DNA Polymerase; Stavudine; Thymidine; Virus Replication; Zidovudine | 1987 |
Antiviral agents with activity against human retroviruses.
Topics: Antiviral Agents; Deltaretrovirus; Dextran Sulfate; Dextrans; Dideoxynucleosides; Fungal Proteins; Glycyrrhetinic Acid; Glycyrrhizic Acid; HIV-1; HIV-2; Human T-lymphotropic virus 1; Lentinan; Polysaccharides; Proteoglycans; Stavudine; Zidovudine | 1989 |
Tetrazolium-based plaque assay for HIV-1 and HIV-2, and its use in the evaluation of antiviral compounds.
Topics: Antiviral Agents; Cell Line; Dideoxynucleosides; HIV-1; HIV-2; Pentosan Sulfuric Polyester; Staining and Labeling; Stavudine; Tetrazolium Salts; Thiazoles; Viral Plaque Assay; Zidovudine | 1989 |
Replication of human immunodeficiency virus in monocytes. Granulocyte/macrophage colony-stimulating factor (GM-CSF) potentiates viral production yet enhances the antiviral effect mediated by 3'-azido-2'3'-dideoxythymidine (AZT) and other dideoxynucleoside
Topics: Cells, Cultured; Colony-Stimulating Factors; Dideoxynucleosides; Granulocyte-Macrophage Colony-Stimulating Factor; Growth Substances; HIV-1; Humans; Lymphocytes; Monocytes; Stavudine; Virus Replication; Zidovudine | 1989 |
Differential patterns of intracellular metabolism of 2',3'-didehydro-2',3'-dideoxythymidine and 3'-azido-2',3'-dideoxythymidine, two potent anti-human immunodeficiency virus compounds.
Topics: Animals; Antiviral Agents; Cell Line; Cell Survival; Deoxycytidine; Deoxyribonucleotides; Dideoxynucleosides; Dose-Response Relationship, Drug; HIV; Humans; Mice; Phosphorylation; Sarcoma Viruses, Murine; Solubility; Stavudine; Thymidine; Zidovudine | 1989 |
Sensitization of X-irradiated Chinese hamster V79 cells by derivatives of pyrimidine nucleosides.
Topics: Animals; Antiviral Agents; Cell Count; Cell Line; Cell Survival; Dideoxynucleosides; Pyrimidine Nucleosides; Radiation-Sensitizing Agents; Stavudine; Zalcitabine; Zidovudine | 1988 |
Both 2',3'-dideoxythymidine and its 2',3'-unsaturated derivative (2',3'-dideoxythymidinene) are potent and selective inhibitors of human immunodeficiency virus replication in vitro.
Topics: Antigens, Viral; Antiviral Agents; Cell Line; Cell Survival; Cytopathogenic Effect, Viral; Dideoxynucleosides; HIV; Humans; Stavudine; Structure-Activity Relationship; Thymidine; Virus Replication; Zidovudine | 1987 |
Inhibitory effect of 2',3'-didehydro-2',3'-dideoxynucleosides on infectivity, cytopathic effects, and replication of human immunodeficiency virus.
Topics: Antigens, Viral; Antiviral Agents; Cells, Cultured; Cytopathogenic Effect, Viral; Dideoxynucleosides; HIV; Humans; Stavudine; Thymidine; Viral Plaque Assay; Virus Replication; Zalcitabine; Zidovudine | 1987 |
HIV-1, the brain, and combination therapy.
Topics: Adult; AIDS Dementia Complex; Antiviral Agents; Child; Didanosine; Drug Combinations; HIV-1; Humans; Lamivudine; Neuroprotective Agents; Stavudine; Zalcitabine; Zidovudine | 1995 |
[AIDS therapy with reverse transcriptase inhibitors].
Topics: Acquired Immunodeficiency Syndrome; Didanosine; Drug Therapy, Combination; Humans; Lamivudine; Reverse Transcriptase Inhibitors; Stavudine; Zalcitabine; Zidovudine | 1993 |
Novel mutation (V75T) in human immunodeficiency virus type 1 reverse transcriptase confers resistance to 2',3'-didehydro-2',3'-dideoxythymidine in cell culture.
Topics: Base Sequence; Cells, Cultured; Drug Resistance, Microbial; Emtricitabine; HeLa Cells; HIV Reverse Transcriptase; HIV-1; Humans; Molecular Sequence Data; Mutation; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Stavudine; Zalcitabine; Zidovudine | 1994 |
Natural occurrence of drug resistance mutations in the reverse transcriptase of human immunodeficiency virus type 1 isolates.
Topics: Amino Acid Sequence; Antiviral Agents; Base Sequence; Cloning, Molecular; DNA, Viral; Drug Resistance, Microbial; HIV Reverse Transcriptase; HIV-1; Humans; Molecular Sequence Data; Mutation; Nevirapine; Point Mutation; Polymerase Chain Reaction; Pyridines; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Stavudine; Virus Cultivation; Zalcitabine; Zidovudine | 1994 |
Drugs for AIDS and associated infections.
Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Opportunistic Infections; Amphotericin B; Antifungal Agents; Antiprotozoal Agents; Antiviral Agents; Atovaquone; Candidiasis, Oral; Clindamycin; Clotrimazole; Cryptosporidiosis; Cytomegalovirus Infections; Dapsone; Didanosine; Drug Combinations; Drug Therapy, Combination; Fluconazole; Flucytosine; Folic Acid Antagonists; Foscarnet; Glucuronates; Herpes Simplex; Herpes Zoster; Humans; Isoniazid; Itraconazole; Ketoconazole; Lamivudine; Mycobacterium avium-intracellulare Infection; Naphthoquinones; Nystatin; Pentamidine; Pneumocystis Infections; Pneumonia, Pneumocystis; Prednisone; Primaquine; Reverse Transcriptase Inhibitors; Stavudine; Syphilis; Toxoplasmosis; Trimetrexate; Tuberculosis; Zalcitabine; Zidovudine | 1995 |
Removal of anti-human immunodeficiency virus 2',3'-dideoxynucleoside monophosphates from DNA by a novel human cytosolic 3'-->5' exonuclease.
Topics: Antiviral Agents; Base Sequence; Cell Line; Cytosol; Dideoxynucleosides; DNA, Single-Stranded; Exonucleases; HIV-1; Humans; Molecular Sequence Data; Phosphates; Stavudine; Stereoisomerism; Substrate Specificity; Virus Replication; Zalcitabine; Zidovudine | 1995 |
Evaluation of the combination effect of different antiviral compounds against HIV in vitro.
Topics: Antiviral Agents; Benzodiazepines; Didanosine; Dideoxynucleosides; Drug Combinations; Drug Evaluation; Drug Synergism; HIV; Humans; Imidazoles; Microbial Sensitivity Tests; Reverse Transcriptase Inhibitors; Stavudine; Zidovudine | 1993 |
Preparation of anti-HIV-low-density lipoprotein complexes for delivery of anti-HIV drugs via the low-density lipoprotein pathways.
Topics: Animals; Antibodies, Monoclonal; Binding, Competitive; Cholic Acids; Drug Carriers; HIV-1; Humans; Lipoproteins, LDL; Macrophages, Peritoneal; Membrane Proteins; Mice; Molecular Structure; Prodrugs; Receptors, Immunologic; Receptors, Lipoprotein; Receptors, Scavenger; Scavenger Receptors, Class B; Stavudine; Structure-Activity Relationship; Zidovudine | 1994 |
The ex vivo transfer of the anti-HIV nucleoside compound d4T in the human placenta.
Topics: Diffusion; Dipyridamole; Female; Fetal Blood; Gestational Age; Humans; Maternal-Fetal Exchange; Perfusion; Placenta; Pregnancy; Stavudine; Thymidine; Zidovudine | 1994 |
Genotypic and phenotypic analysis of human immunodeficiency virus type 1 isolates from patients on prolonged stavudine therapy.
Topics: Acquired Immunodeficiency Syndrome; Base Sequence; Drug Resistance; Genotype; HIV-1; Humans; Molecular Sequence Data; Phenotype; Stavudine; Zidovudine | 1994 |
Generation of multiple drug resistance by sequential in vitro passage of the human immunodeficiency virus type 1.
Topics: Antiviral Agents; Cell Line; Cloning, Molecular; Didanosine; Drug Interactions; Drug Resistance, Microbial; HIV-1; Humans; Interferon-alpha; Neutralization Tests; Phenotype; Serial Passage; Stavudine; Zalcitabine; Zidovudine | 1994 |
Comparative embryonic cytotoxicity of antiretroviral nucleosides.
Topics: Animals; Antiviral Agents; Culture Techniques; Didanosine; Embryo, Mammalian; HIV; Mice; Nucleosides; Stavudine; Zalcitabine; Zidovudine | 1994 |
In vitro and in vivo disposition and metabolism of 3'-deoxy-2',3'-didehydrothymidine.
Topics: Aminoisobutyric Acids; Animals; Antiviral Agents; Biological Availability; Biotransformation; Chromatography, High Pressure Liquid; Feces; HIV; In Vitro Techniques; Injections, Intravenous; Injections, Subcutaneous; Liver; Macaca fascicularis; Macaca mulatta; Rats; Rats, Sprague-Dawley; Stavudine; Thymine; Zidovudine | 1993 |
Factors associated with changes in the use of antiretroviral therapy by a cohort of homosexual men infected with human immunodeficiency virus type 1.
Topics: Antiviral Agents; CD4 Lymphocyte Count; Cohort Studies; Didanosine; Drug Therapy, Combination; Drug Utilization; Follow-Up Studies; Hemoglobins; HIV Infections; HIV-1; Homosexuality, Male; Humans; Male; Multicenter Studies as Topic; Reverse Transcriptase Inhibitors; Stavudine; Zalcitabine; Zidovudine | 1995 |
Drug combinations and effect parameters of zidovudine, stavudine, and nevirapine in standardized drug-sensitive and resistant HIV type 1 strains.
Topics: Antiviral Agents; Cell Line, Transformed; Cytotoxicity, Immunologic; Drug Resistance, Microbial; Drug Therapy, Combination; HIV Infections; HIV-1; Microbial Sensitivity Tests; Nevirapine; Pyridines; Stavudine; T-Lymphocytes; Zidovudine | 1996 |
Comparative kinetic analyses of interaction of inhibitors with Rauscher murine leukemia virus and human immunodeficiency virus reverse transcriptases.
Topics: Adenine; Antiviral Agents; HIV Reverse Transcriptase; HIV-1; Kinetics; Organophosphonates; Phosphates; Rauscher Virus; Reverse Transcriptase Inhibitors; Stavudine; Virus Replication; Zidovudine | 1996 |
Zidovudine does not affect transplacental transfer or systemic clearance of stavudine (2',3'-didehydro-3'-deoxythymidine) in the pigtailed macaque (Macaca nemestrina).
Topics: Animals; Drug Interactions; Female; Infusions, Intravenous; Macaca nemestrina; Maternal-Fetal Exchange; Metabolic Clearance Rate; Placenta; Pregnancy; Stavudine; Zidovudine | 1996 |
Intracellular metabolism of zidovudine and stavudine in combination.
Topics: Antiviral Agents; Cells, Cultured; Drug Combinations; Genetic Variation; HIV Infections; HIV-1; Humans; Leukocytes, Mononuclear; Phosphorylation; Stavudine; Zidovudine | 1996 |
Therapy of HIV infections: problems and prospects.
Topics: Anti-HIV Agents; Didanosine; Drug Resistance, Microbial; HIV; HIV Infections; HIV Protease Inhibitors; Humans; Stavudine; Urban Health; Zalcitabine; Zidovudine | 1996 |
Didanosine (ddl) and stavudine (d4T): absence of peripheral neurotoxicity in rabbits.
Topics: Animals; Antiviral Agents; Didanosine; Male; Microscopy, Electron; Neural Conduction; Neurons; Peripheral Nerves; Rabbits; Sciatic Nerve; Spinal Nerves; Stavudine; Zidovudine | 1995 |
Intestinal absorption and first-pass elimination of 2', 3'-dideoxynucleosides following oral administration in rats.
Topics: Administration, Oral; Animals; Anti-HIV Agents; Area Under Curve; Biological Availability; Didanosine; Dideoxynucleosides; Intestinal Absorption; Intestinal Mucosa; Male; Rats; Rats, Wistar; Stavudine; Zidovudine | 1996 |
Stavudine selectively induces apoptosis in HIV type 1-infected cells.
Topics: Anti-HIV Agents; Apoptosis; Cell Line; Didanosine; DNA Fragmentation; Down-Regulation; HIV Reverse Transcriptase; HIV-1; Humans; Nevirapine; Proto-Oncogene Proteins c-bcl-2; Pyridines; Reverse Transcriptase Inhibitors; Stavudine; T-Lymphocytes; Thymidine; Zalcitabine; Zidovudine | 1997 |
Effect of nucleoside analogs on neurite regeneration and mitochondrial DNA synthesis in PC-12 cells.
Topics: Animals; Didanosine; Dideoxynucleosides; DNA Replication; DNA, Mitochondrial; Nerve Growth Factors; Neurites; PC12 Cells; Phosphorylation; Rats; Stavudine; Zalcitabine; Zidovudine | 1997 |
Hearing loss and antiretroviral therapy in patients infected with HIV-1.
Topics: Adult; Anti-HIV Agents; Didanosine; Female; Hearing Disorders; HIV Infections; HIV-1; Humans; Male; Middle Aged; Stavudine; Zidovudine | 1997 |
Treatment options for human immunodeficiency virus.
Topics: Acquired Immunodeficiency Syndrome; Adult; Antiviral Agents; Child; Didanosine; Drug Approval; Female; HIV Infections; HIV Protease Inhibitors; Humans; Infant, Newborn; Lamivudine; Male; Saquinavir; Stavudine; United States; United States Food and Drug Administration; Zalcitabine; Zidovudine | 1996 |
Phenotypic variations and switches in HIV isolated from the blood and the gastrointestinal tissues of patients with HIV-1 infection. HIV/GI Research Study Group.
Topics: Biopsy; Didanosine; Digestive System; Female; Giant Cells; HIV; HIV Enteropathy; HIV Infections; Humans; Male; Mutation; Phenotype; Prospective Studies; Stavudine; Viral Load; Zidovudine | 1997 |
[Therapy of HIV infection: combination drug therapy effective, immunotherapy still experimental].
Topics: Animals; Anti-HIV Agents; CD4 Lymphocyte Count; HIV Infections; Humans; Immunotherapy; Interleukin-2; Stavudine; Zidovudine | 1997 |
Correlation between plasma HIV-1 RNA levels and the rate of immunologic decline.
Topics: Anti-HIV Agents; beta 2-Microglobulin; CD4 Lymphocyte Count; Didanosine; Disease Progression; DNA, Viral; Drug Therapy, Combination; HIV Core Protein p24; HIV Infections; HIV-1; Humans; Longitudinal Studies; RNA, Viral; Stavudine; Viral Load; Viremia; Virus Replication; Zalcitabine; Zidovudine | 1997 |
Effects of drugs on 2',3'-dideoxy-2',3'-didehydrothymidine phosphorylation in vitro.
Topics: Anti-HIV Agents; Cells, Cultured; Drug Interactions; Humans; Leukemia, Monocytic, Acute; Leukocytes, Mononuclear; Phosphorylation; Phytohemagglutinins; Stavudine; Stimulation, Chemical; Thymidine; Zidovudine | 1997 |
Microdialysis studies of the distribution of stavudine into the central nervous system in the freely-moving rat.
Topics: Animals; Anti-HIV Agents; Central Nervous System; Drug Interactions; Infusions, Intravenous; Injections, Intraventricular; Male; Microdialysis; Rats; Rats, Sprague-Dawley; Stavudine; Tissue Distribution; Zidovudine | 1997 |
Cure or control of HIV/AIDS?
Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Didanosine; Drug Resistance, Microbial; Drug Therapy, Combination; HIV; HIV Infections; Humans; Indinavir; Lamivudine; Models, Biological; Nevirapine; Pyridines; Ritonavir; Saquinavir; Stavudine; Zalcitabine; Zidovudine | 1997 |
[Anti-retrovirals].
Topics: Anti-HIV Agents; Didanosine; Reverse Transcriptase Inhibitors; Stavudine; Zalcitabine; Zidovudine | 1997 |
Metabolism and activities of 3'-azido-2',3'-dideoxythymidine and 2',3'-didehydro-2',3'-dideoxythymidine in herpesvirus thymidine kinase transduced T-lymphocytes.
Topics: Acyclovir; Cell Line; Dose-Response Relationship, Drug; Ganciclovir; Genetic Therapy; Growth Inhibitors; Herpesvirus 1, Human; HIV-1; Humans; Hydroxyurea; Nucleosides; Stavudine; Substrate Specificity; T-Lymphocytes; Thymidine Kinase; Zalcitabine; Zidovudine | 1997 |
Lamivudine (3TC) phosphorylation and drug interactions in vitro.
Topics: Anti-HIV Agents; Cells, Cultured; Deoxycytidine; Didanosine; Dideoxynucleosides; Drug Interactions; Humans; Kinetics; Lamivudine; Lymphocyte Activation; Lymphocytes; Mitogens; Models, Chemical; Monocytes; Phosphorylation; Stavudine; Tumor Cells, Cultured; Zalcitabine; Zidovudine | 1997 |
Protease inhibitor therapy in children with perinatally acquired HIV infection.
Topics: Anti-HIV Agents; Child; Child, Preschool; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Indinavir; Infant; Infectious Disease Transmission, Vertical; Lamivudine; Male; Protease Inhibitors; Retrospective Studies; Ritonavir; Saquinavir; Stavudine; Zidovudine | 1997 |
[HIV-therapy: as early and as intensive as possible].
Topics: Anti-HIV Agents; Clinical Trials as Topic; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Reverse Transcriptase Inhibitors; Stavudine; Time Factors; Treatment Outcome; Zidovudine | 1997 |
A controlled trial of double versus triple therapy for HIV.
Topics: Anti-HIV Agents; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; Humans; Stavudine; Zidovudine | 1998 |
Effect of protease inhibitors on nucleoside analogue phosphorylation in vitro.
Topics: Anti-HIV Agents; Cell Count; Cell Survival; Didanosine; Drug Interactions; Humans; Indinavir; Lamivudine; Leukocytes, Mononuclear; Nucleosides; Phosphorylation; Protease Inhibitors; Ritonavir; Saquinavir; Stavudine; Trypan Blue; Tumor Cells, Cultured; Zalcitabine; Zidovudine | 1998 |
Survival in 2367 zidovudine-treated patients according to use of other nucleoside analogue drugs. The EuroSIDA Study Group.
Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Cohort Studies; Didanosine; Dideoxynucleosides; Disease Progression; Drug Therapy, Combination; Europe; Female; Follow-Up Studies; HIV Infections; Humans; Lamivudine; Male; Middle Aged; Proportional Hazards Models; Prospective Studies; Stavudine; Survival Analysis; Zalcitabine; Zidovudine | 1998 |
TXU (anti-CD7)-pokeweed antiviral protein as a potent inhibitor of human immunodeficiency virus.
Topics: Acquired Immunodeficiency Syndrome; Animals; Anti-HIV Agents; Disease Models, Animal; HIV-1; Humans; Immunoconjugates; Macaca fascicularis; Mice; Mice, SCID; N-Glycosyl Hydrolases; Plant Proteins; Ribosome Inactivating Proteins, Type 1; Stavudine; Zidovudine | 1998 |
Regression of cytomegalovirus retinitis associated with protease-inhibitor treatment in patients with AIDS.
Topics: AIDS-Related Opportunistic Infections; Anti-HIV Agents; Cytomegalovirus Retinitis; Drug Therapy, Combination; HIV Protease Inhibitors; Humans; Lamivudine; Saquinavir; Stavudine; Zidovudine | 1998 |
Clinical and biological impact of antiretroviral therapy with protease inhibitors on HIV-related Kaposi's sarcoma.
Topics: Adult; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Didanosine; Dideoxynucleosides; Drug Therapy, Combination; Female; Herpesvirus 8, Human; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Male; Middle Aged; Prospective Studies; Reverse Transcriptase Inhibitors; Ritonavir; Saquinavir; Sarcoma, Kaposi; Stavudine; Treatment Outcome; Viral Load; Viremia; Zalcitabine; Zidovudine | 1998 |
The M184V mutation in HIV-1 reverse transcriptase (RT) conferring lamivudine resistance does not result in broad cross-resistance to nucleoside analogue RT inhibitors.
Topics: Anti-HIV Agents; Cohort Studies; Didanosine; Dideoxynucleosides; Drug Resistance, Microbial; Drug Resistance, Multiple; Drug Therapy, Combination; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Methionine; Point Mutation; Reverse Transcriptase Inhibitors; Stavudine; Valine; Zalcitabine; Zidovudine | 1998 |
Discrepant responses to triple combination antiretroviral therapy in advanced HIV disease.
Topics: Adult; Aged; Anti-HIV Agents; Cohort Studies; Drug Therapy, Combination; Female; Follow-Up Studies; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Male; Middle Aged; Prospective Studies; Reverse Transcriptase Inhibitors; Stavudine; Treatment Outcome; Zidovudine | 1998 |
Persistence of HIV-1 variants harbouring the zidovudine resistance mutation at pol codon 215 in patients who respond to triple combination therapy.
Topics: Adult; Anti-HIV Agents; Codon; Drug Resistance, Microbial; Drug Therapy, Combination; Female; Genes, pol; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Indinavir; Lamivudine; Male; Mutation; Prospective Studies; Reverse Transcriptase Inhibitors; Stavudine; Treatment Outcome; Virus Latency; Zidovudine | 1998 |
Antiretroviral triple therapy decreases HIV viral load but does not alter hepatitis C virus (HCV) serum levels in HIV-HCV-co-infected haemophiliacs.
Topics: AIDS-Related Opportunistic Infections; Anti-HIV Agents; Cohort Studies; Drug Therapy, Combination; Hemophilia A; Hepacivirus; Hepatitis C; HIV; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Reverse Transcriptase Inhibitors; RNA, Viral; Saquinavir; Stavudine; Treatment Outcome; Viral Load; Zidovudine | 1998 |
Metabolism of 2',3'-dideoxy-2',3'-didehydro-beta-L(-)-5-fluorocytidine and its activity in combination with clinically approved anti-human immunodeficiency virus beta-D(+) nucleoside analogs in vitro.
Topics: Anti-HIV Agents; Cell Line; Deamination; Deoxycytidine Kinase; Didanosine; DNA Polymerase gamma; DNA-Directed DNA Polymerase; DNA, Mitochondrial; DNA, Viral; Drug Interactions; HIV Reverse Transcriptase; HIV-1; Phosphorylation; Stavudine; Virus Replication; Zalcitabine; Zidovudine | 1998 |
Risk of HIV dementia and opportunistic brain disease in AIDS and zidovudine therapy.
Topics: Acquired Immunodeficiency Syndrome; Adult; AIDS Dementia Complex; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Brain Diseases; Didanosine; Female; Follow-Up Studies; Humans; Longitudinal Studies; Male; Retrospective Studies; Risk; Stavudine; Treatment Outcome; Zalcitabine; Zidovudine | 1998 |
Clinical experience with adding delavirdine to combination therapy in patients in whom multiple antiretroviral treatment including protease inhibitors has failed.
Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Delavirdine; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Indinavir; Lamivudine; Male; Middle Aged; Reverse Transcriptase Inhibitors; RNA, Viral; Stavudine; Treatment Failure; Viral Load; Zidovudine | 1998 |
Neurological efficacy of stavudine, zidovudine, and lamivudine.
Topics: AIDS Dementia Complex; Anti-HIV Agents; beta 2-Microglobulin; Blood-Brain Barrier; Brain; HIV-1; Humans; Lamivudine; Meninges; RNA, Viral; Stavudine; Virus Shedding; Zidovudine | 1998 |
Neurological efficacy of stavudine, zidovudine, and lamivudine.
Topics: AIDS Dementia Complex; Anti-HIV Agents; Brain; Female; Follow-Up Studies; HIV-1; Humans; Indinavir; Lamivudine; Neopterin; RNA, Viral; Stavudine; Viral Load; Virus Replication; Zidovudine | 1998 |
Cerebrospinal fluid levels of antiretroviral medications: abstract and commentary.
Topics: Anti-HIV Agents; Blood-Brain Barrier; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Lamivudine; RNA, Viral; Stavudine; Zidovudine | 1998 |
[Weak antiviral effect of changing two nucleoside analogues combined with antiretroviral agents. 3TC and d4T after ZDU and ddi or ddc].
Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Didanosine; Drug Therapy, Combination; Female; HIV Seropositivity; HIV-1; Humans; Lamivudine; Male; Retrospective Studies; Stavudine; Viral Load; Zalcitabine; Zidovudine | 1998 |
The transport of the anti-HIV drug, 2',3'-didehydro-3'-deoxythymidine (D4T), across the blood-brain and blood-cerebrospinal fluid barriers.
Topics: Analysis of Variance; Animals; Anti-HIV Agents; Biological Transport; Blood-Brain Barrier; Brain; Guinea Pigs; Reverse Transcriptase Inhibitors; Stavudine; Thymidine; Zidovudine | 1998 |
High incidence of nevirapine-associated rash in HIV-infected Chinese.
Topics: Anti-HIV Agents; CD4 Lymphocyte Count; China; Didanosine; Drug Eruptions; Drug Therapy, Combination; HIV Infections; Humans; Nevirapine; Reverse Transcriptase Inhibitors; Stavudine; Zidovudine | 1998 |
[Clinical case of the month. Apropos of pancytopenia in a seropositive patient].
Topics: Adult; Anemia, Aplastic; Anti-HIV Agents; Bone Marrow; HIV Infections; HIV Seropositivity; HIV-1; Humans; Indinavir; Lamivudine; Male; Pancytopenia; Stavudine; Zidovudine | 1998 |
Suppression of replication of multidrug-resistant HIV type 1 variants by combinations of thymidylate synthase inhibitors with zidovudine or stavudine.
Topics: Anti-HIV Agents; Antimetabolites; Drug Interactions; Drug Resistance, Microbial; Drug Resistance, Multiple; Floxuridine; Fluorouracil; HIV-1; Humans; Mutation; Reverse Transcriptase Inhibitors; Stavudine; Thymidylate Synthase; Thymine Nucleotides; Virus Replication; Zidovudine | 1999 |
AIDS: the new drug war.
Topics: Acquired Immunodeficiency Syndrome; Black or African American; Dideoxynucleosides; Drug Combinations; Drug Industry; Humans; Investments; Lamivudine; Stavudine; United States; Zidovudine | 1998 |
Stavudine in zidovudine (ZDV)-experienced compared with ZDV-naive patients.
Topics: Adult; Anti-HIV Agents; Female; HIV Infections; HIV-1; Humans; Male; Prospective Studies; Reverse Transcriptase Inhibitors; Stavudine; Zidovudine | 1999 |
Combination antiretroviral therapy including ritonavir in children infected with human immunodeficiency.
Topics: Adolescent; Anti-HIV Agents; Child; Child, Preschool; Drug Therapy, Combination; Female; Follow-Up Studies; HIV Infections; HIV Protease Inhibitors; Humans; Lamivudine; Male; Reverse Transcriptase Inhibitors; Ritonavir; Stavudine; Zidovudine | 1999 |
Intracellular activation of 2',3'-dideoxyinosine and drug interactions in vitro.
Topics: Anti-HIV Agents; Deoxyadenine Nucleotides; Didanosine; Dideoxynucleotides; Drug Interactions; Guanosine; Humans; Hydroxyurea; Inosine; Intracellular Fluid; Lamivudine; Pentoxifylline; Stavudine; U937 Cells; Zidovudine | 1999 |
Levels of human immunodeficiency virus type 1-specific cytotoxic T-lymphocyte effector and memory responses decline after suppression of viremia with highly active antiretroviral therapy.
Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Cytotoxicity, Immunologic; Drug Therapy, Combination; Epitopes, T-Lymphocyte; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Immunologic Memory; Indinavir; Lamivudine; Longitudinal Studies; Reverse Transcriptase Inhibitors; Stavudine; T-Lymphocytes, Cytotoxic; Viral Load; Viremia; Zidovudine | 1999 |
Antiviral effect of AZT versus stavudine in combination with lamivudine and indinavir in the context of a populational study.
Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Indinavir; Lamivudine; Male; Stavudine; Viremia; Zidovudine | 1999 |
Synthesis and anti-HIV activity of some novel arylphosphate and H-phosphonate derivatives of 3'-azido-2',3'-dideoxythymidine and 2',3'-didehydro-2',3'-dideoxythymidine.
Topics: Anti-HIV Agents; Cell Line; Drug Evaluation, Preclinical; HIV-1; Humans; Phosphoric Acids; Reverse Transcriptase Inhibitors; Stavudine; Zidovudine | 1999 |
Characterization of the activation pathway of phosphoramidate triester prodrugs of stavudine and zidovudine.
Topics: Amino Acids; Animals; Anti-HIV Agents; Biotransformation; Dideoxynucleotides; Drug Design; Esterases; Esters; HIV; Humans; Liver; Male; Mice; Nucleosides; Prodrugs; Rats; Rats, Wistar; Reverse Transcriptase Inhibitors; Stavudine; Thymine Nucleotides; Tumor Cells, Cultured; Zidovudine | 1999 |
Use of recombinant viruses to assess the pattern of early human immunodeficiency virus breakthrough infection in the presence of stavudine.
Topics: Animals; Anti-HIV Agents; COS Cells; Defective Viruses; Floxuridine; HeLa Cells; HIV; Humans; Jurkat Cells; Leukemia Virus, Murine; Recombination, Genetic; Stavudine; Zidovudine | 1999 |
A syndrome of peripheral fat wasting (lipodystrophy) in patients receiving long-term nucleoside analogue therapy.
Topics: Adipose Tissue; Adult; Aged; Body Composition; Cross-Sectional Studies; Energy Intake; Female; Glucose Tolerance Test; HIV Infections; HIV Wasting Syndrome; Humans; Lipids; Lipodystrophy; Male; Middle Aged; Reverse Transcriptase Inhibitors; Risk Factors; Stavudine; Syndrome; Zidovudine | 1999 |
Emergence of zidovudine and multidrug-resistance mutations in the HIV-1 reverse transcriptase gene in therapy-naive patients receiving stavudine plus didanosine combination therapy. STADI Group.
Topics: Adult; Anti-HIV Agents; Didanosine; Drug Resistance, Multiple; Drug Therapy, Combination; HIV Infections; HIV Reverse Transcriptase; Humans; Mutation; Reverse Transcriptase Inhibitors; Stavudine; Viral Load; Zidovudine | 1999 |
Intracellular metabolism of CycloSaligenyl 3'-azido-2', 3'-dideoxythymidine monophosphate, a prodrug of 3'-azido-2', 3'-dideoxythymidine (zidovudine).
Topics: Anti-HIV Agents; Cell Line; Culture Media; Dideoxynucleotides; Drug Stability; Humans; Hydrogen-Ion Concentration; Organophosphates; Prodrugs; Stavudine; Thymidine Kinase; Thymine Nucleotides; Tritium; Tumor Cells, Cultured; Zidovudine | 1999 |
Highly active anti-retroviral therapy (HAART) is associated with a lower level of CD4+ T cell apoptosis in HIV-infected patients.
Topics: Adult; Aged; Anti-HIV Agents; Apoptosis; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Didanosine; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; Humans; Lamivudine; Male; Middle Aged; Multivariate Analysis; Retrospective Studies; Stavudine; Viral Load; Zalcitabine; Zidovudine | 1999 |
Advanced Hodgkin's disease in a pregnant HIV seropositive woman: favorable mother and baby outcome following combined anticancer and antiretroviral therapy.
Topics: Adult; Anti-HIV Agents; Antineoplastic Combined Chemotherapy Protocols; Drug Therapy, Combination; Female; HIV Seropositivity; Hodgkin Disease; Humans; Lamivudine; Male; Pregnancy; Pregnancy Complications, Infectious; Pregnancy Complications, Neoplastic; Pregnancy Outcome; Remission Induction; Stavudine; Zidovudine | 2000 |
Potential multifunctional inhibitors of HIV-1 reverse transcriptase. Novel [AZT]-[TSAO-T] and [d4T]-[TSAO-T] heterodimers modified in the linker and in the dideoxynucleoside region.
Topics: Anti-HIV Agents; Cell Line; Dimerization; HIV-1; HIV-2; Humans; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Reverse Transcriptase Inhibitors; Spectrometry, Mass, Fast Atom Bombardment; Spiro Compounds; Stavudine; Thymidine; Uridine; Zidovudine | 1999 |
Incidence and predictors of virologic failure of antiretroviral triple-drug therapy in a community-based cohort.
Topics: Adult; Aged; Anti-HIV Agents; CD4 Lymphocyte Count; Cohort Studies; Didanosine; Disease Progression; Drug Administration Schedule; Drug Resistance, Microbial; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Incidence; Indinavir; Lamivudine; Male; Middle Aged; Reverse Transcriptase Inhibitors; Risk Factors; Ritonavir; RNA, Viral; Salvage Therapy; Saquinavir; Stavudine; Switzerland; Treatment Failure; Viral Load; Zalcitabine; Zidovudine | 1999 |
Evaluation of antiretroviral drug efficacy for HIV-1 encephalitis in SCID mice.
Topics: AIDS Dementia Complex; Animals; Cells, Cultured; Didanosine; Dideoxynucleosides; Disease Models, Animal; HIV-1; Humans; Lamivudine; Male; Mice; Mice, SCID; Monocytes; Reverse Transcriptase Inhibitors; Stavudine; Virus Replication; Zidovudine | 2000 |
Drugs for HIV infection.
Topics: Anti-HIV Agents; Didanosine; Dideoxynucleosides; Drug Costs; Drug Therapy, Combination; Female; HIV Infections; Humans; Infectious Disease Transmission, Vertical; Lamivudine; Pregnancy; Pregnancy Complications, Infectious; Reverse Transcriptase Inhibitors; Stavudine; Zalcitabine; Zidovudine | 2000 |
Phenotypic and genotypic resistance patterns of HIV-1 isolates derived from individuals treated with didanosine and stavudine.
Topics: Anti-HIV Agents; Didanosine; Drug Resistance, Microbial; Drug Resistance, Multiple; Drug Therapy, Combination; Follow-Up Studies; Genotype; HIV Infections; HIV-1; Humans; Mutation; Phenotype; Polymerase Chain Reaction; RNA-Directed DNA Polymerase; RNA, Viral; Stavudine; Viral Load; Zidovudine | 2000 |
Early immune reconstitution after potent antiretroviral therapy in HIV-infected children correlates with the increase in thymus volume.
Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Child; Cohort Studies; Didanosine; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Organ Size; Reverse Transcriptase Inhibitors; Stavudine; Thymus Gland; Viral Load; Zidovudine | 2000 |
Predicting the duration of antiviral treatment needed to suppress plasma HIV-1 RNA.
Topics: Adult; Anti-HIV Agents; Carbamates; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; Cohort Studies; Dideoxynucleosides; Furans; HIV Infections; HIV Protease Inhibitors; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Lymph Nodes; Nelfinavir; Reverse Transcriptase Inhibitors; RNA, Viral; Saquinavir; Stavudine; Sulfonamides; Time Factors; Viral Load; Viremia; Zidovudine | 2000 |
Mitigation of hepato-cellular injury caused by HAART with glycyrrhizin compound in patients co-infected with HIV and HCV.
Topics: Anti-HIV Agents; Chemical and Drug Induced Liver Injury; Cysteine; Drug Combinations; Drug Therapy, Combination; Glycine; Glycyrrhetinic Acid; Hemophilia A; Hepatitis C; HIV Infections; HIV Protease Inhibitors; Humans; Lamivudine; Reverse Transcriptase Inhibitors; Stavudine; Viral Load; Zalcitabine; Zidovudine | 1999 |
The mechanism of phosphorylation of anti-HIV D4T by nucleoside diphosphate kinase.
Topics: Adenosine Triphosphate; Anti-HIV Agents; Dideoxynucleotides; HIV Reverse Transcriptase; Humans; Kinetics; Nucleoside-Diphosphate Kinase; Phosphorylation; Stavudine; Thymine Nucleotides; Zidovudine | 2000 |
Lipodystrophy and long-term therapy with nucleoside reverse transcriptase inhibitors.
Topics: Anti-HIV Agents; HIV Infections; Humans; Lipodystrophy; Reverse Transcriptase Inhibitors; Stavudine; Time Factors; Zidovudine | 2000 |
Emergence of zidovudine resistance in HIV-infected patients receiving stavudine.
Topics: Adult; Anti-HIV Agents; Drug Resistance, Microbial; Drug Therapy, Combination; Female; HIV; HIV Infections; Humans; Male; Stavudine; Zidovudine | 2000 |
Causes of macrocytosis in HIV-infected patients not treated with zidovudine. Swiss HIV Cohort Study.
Topics: Adult; Anti-HIV Agents; Case-Control Studies; Drug Therapy, Combination; Erythrocyte Indices; Female; HIV Infections; Humans; Male; Middle Aged; Reverse Transcriptase Inhibitors; Stavudine; Zidovudine | 2000 |
Cutaneous side effects induced by indinavir.
Topics: Adult; Alopecia; Didanosine; Drug Eruptions; Drug Therapy, Combination; Female; HIV; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Lipodystrophy; Male; Middle Aged; Pruritus; Pyoderma Gangrenosum; Retrospective Studies; Reverse Transcriptase Inhibitors; RNA, Viral; Scalp Dermatoses; Skin; Stavudine; Zalcitabine; Zidovudine | 2000 |
Enhanced penetration of indinavir in cerebrospinal fluid and semen after the addition of low-dose ritonavir.
Topics: Adult; Antiretroviral Therapy, Highly Active; Dideoxynucleosides; Disease Reservoirs; HIV Protease Inhibitors; HIV-1; Humans; Indinavir; Lamivudine; Male; Middle Aged; Nevirapine; Reverse Transcriptase Inhibitors; Ritonavir; RNA, Viral; Semen; Stavudine; Viral Load; Zidovudine | 2000 |
Structural basis for activation of alpha-boranophosphate nucleotide analogues targeting drug-resistant reverse transcriptase.
Topics: Anti-HIV Agents; Boron Compounds; Crystallography, X-Ray; DNA Repair; Drug Resistance, Microbial; HIV Reverse Transcriptase; HIV-1; Humans; Kinetics; Models, Molecular; Molecular Conformation; Nucleoside-Diphosphate Kinase; Protein Binding; Reverse Transcriptase Inhibitors; Stavudine; Structure-Activity Relationship; Thymidine; Transcription, Genetic; Zidovudine | 2000 |
A facile synthesis of 1-(5'-O-acetyl-3'-O-benzyl-beta-D-xylofuranosyl)thymidine: a potentially viable intermediate for the preparation of the anti-AIDS drugs, AZT and D4T.
Topics: Anti-HIV Agents; Stavudine; Thymidine; Zidovudine | 2000 |
Contribution of nucleoside analogue reverse transcriptase inhibitors to subcutaneous fat wasting in patients with HIV infection.
Topics: Absorptiometry, Photon; Adipose Tissue; Adult; Cohort Studies; Didanosine; Female; HIV Infections; HIV Protease Inhibitors; HIV Wasting Syndrome; Humans; Lamivudine; Longitudinal Studies; Male; Middle Aged; Reverse Transcriptase Inhibitors; Risk Factors; Stavudine; Time Factors; Zidovudine | 2000 |
[Conditions of "thymidine analog mutations" (TAMs) in naive patients treated with different combinations of d4T].
Topics: Anti-HIV Agents; Drug Resistance; Humans; Lamivudine; Mutation; Reverse Transcriptase Inhibitors; Stavudine; Thymidine; Zidovudine | 2000 |
Drug resistance and drug combination features of the human immunodeficiency virus inhibitor, BCH-10652 [(+/-)-2'-deoxy-3'-oxa-4'-thiocytidine, dOTC].
Topics: Anti-HIV Agents; Cells, Cultured; Deoxycytidine; Didanosine; Drug Combinations; Drug Resistance, Microbial; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Indinavir; Lamivudine; Molecular Structure; Mutation; Nevirapine; Reverse Transcriptase Inhibitors; Ritonavir; Saquinavir; Stavudine; T-Lymphocytes; Thionucleosides; Zidovudine | 2000 |
[Cost effectiveness analysis of highly active antiretroviral therapy in HIV asymptomatic patients].
Topics: Adult; Anti-HIV Agents; Cost-Benefit Analysis; Didanosine; Drug Therapy, Combination; Female; HIV Seropositivity; Humans; Indinavir; Lamivudine; Male; Middle Aged; Nevirapine; Sickness Impact Profile; Spain; Stavudine; Viral Load; Zidovudine | 2000 |
Absence of association between individual thymidine analogues or nonnucleoside analogues and lipid abnormalities in HIV-1-infected persons on initial therapy.
Topics: Adult; Alkynes; Anti-HIV Agents; Arteriosclerosis; Benzoxazines; Cholesterol; Cyclopropanes; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Lipids; Male; Nevirapine; Oxazines; Risk Factors; Stavudine; Thymidine; Triglycerides; Zidovudine | 2000 |
Cyclosaligenyl-2',3'-didehydro-2',3'-dideoxythymidine monophosphate: efficient intracellular delivery of d4TMP.
Topics: 5'-Nucleotidase; Anti-HIV Agents; Culture Media; Dideoxynucleotides; Half-Life; Humans; Hydrogen-Ion Concentration; Leukocytes, Mononuclear; Macrophages; Monocytes; Stavudine; Thymidine; Thymidine Kinase; Thymidine Monophosphate; Thymine Nucleotides; Time Factors; Tritium; Tumor Cells, Cultured; Zidovudine | 2000 |
Efavirenz is a potent nonnucleoside reverse transcriptase inhibitor of HIV type 1 replication in microglia in vitro.
Topics: Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Cells, Cultured; Coculture Techniques; Cyclopropanes; HIV-1; Humans; Microglia; Neuroglia; Nucleosides; Oxazines; Reverse Transcriptase Inhibitors; Stavudine; Virus Replication; Zalcitabine; Zidovudine | 2000 |
Differential removal of thymidine nucleotide analogues from blocked DNA chains by human immunodeficiency virus reverse transcriptase in the presence of physiological concentrations of 2'-deoxynucleoside triphosphates.
Topics: Adenosine Triphosphate; Dideoxynucleotides; DNA Primers; HIV Reverse Transcriptase; Reverse Transcriptase Inhibitors; Stavudine; Templates, Genetic; Thymidine Monophosphate; Thymine Nucleotides; Zidovudine | 2000 |
Infection by zidovudine-resistant HIV-1 compromises the virological response to stavudine in a drug-naive patient.
Topics: Anti-HIV Agents; Drug Resistance, Microbial; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Mutation; Phenotype; Reverse Transcriptase Inhibitors; Stavudine; Zidovudine | 2000 |
Sustained responses to dual nucleoside therapy in women.
Topics: Adult; CD4 Lymphocyte Count; Didanosine; Drug Therapy, Combination; Female; HIV Infections; Humans; Lamivudine; Middle Aged; Reverse Transcriptase Inhibitors; Stavudine; Viral Load; Zidovudine | 2000 |
Lipoatrophy, fat accumulation, and mixed syndrome in protease inhibitor-naive HIV-infected patients.
Topics: Adult; Anti-HIV Agents; Body Composition; Female; HIV Infections; Humans; Lipodystrophy; Male; Reverse Transcriptase Inhibitors; Stavudine; Zidovudine | 2000 |
Simultaneous quantitation of the 5'-triphosphate metabolites of zidovudine, lamivudine, and stavudine in peripheral mononuclear blood cells of HIV infected patients by high-performance liquid chromatography tandem mass spectrometry.
Topics: Anti-HIV Agents; Calibration; Chromatography, High Pressure Liquid; Cytidine Triphosphate; Dideoxynucleotides; Drug Therapy, Combination; HIV Infections; Humans; Lamivudine; Mass Spectrometry; Monocytes; Reference Standards; Sensitivity and Specificity; Stavudine; Thymine Nucleotides; Zidovudine | 2000 |
The valine-to-threonine 75 substitution in human immunodeficiency virus type 1 reverse transcriptase and its relation with stavudine resistance.
Topics: Adenosine Triphosphate; Anti-HIV Agents; Antiviral Agents; Binding Sites; Cell Line; DNA; DNA Repair; Drug Resistance; HeLa Cells; HIV Reverse Transcriptase; Humans; Inhibitory Concentration 50; Kinetics; Models, Molecular; Plasmids; Recombinant Proteins; Stavudine; Threonine; Time Factors; Transfection; Tyrosine; Valine; Zidovudine | 2001 |
Reduction in CD8+ cell noncytotoxic anti-HIV activity in individuals receiving highly active antiretroviral therapy during primary infection.
Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4-CD8 Ratio; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Depression, Chemical; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Hydroxyurea; Immunity, Cellular; Indinavir; Lamivudine; Lymphocyte Count; Male; Middle Aged; Nelfinavir; Reverse Transcriptase Inhibitors; RNA, Viral; Stavudine; Treatment Refusal; Viral Load; Viremia; Zidovudine | 2001 |
Phenotypic resistance pattern of HIV-1 isolates with zidovudine and/or multidrug resistance mutations after didanosine-stavudine combination therapy.
Topics: Anti-HIV Agents; Didanosine; Drug Resistance, Microbial; Drug Resistance, Multiple; Drug Therapy, Combination; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Mutation; Phenotype; Reverse Transcriptase Inhibitors; Stavudine; Viral Load; Zidovudine | 2000 |
Protease inhibitor therapy in HIV-infected children.
Topics: Adolescent; Age Factors; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Child; Child, Preschool; Didanosine; Female; HIV Infections; HIV Protease Inhibitors; Humans; Infant; Lamivudine; Male; Nelfinavir; Patient Compliance; Retrospective Studies; Stavudine; Treatment Outcome; Viral Load; Zidovudine | 2000 |
Correlation between intracellular pharmacological activation of nucleoside analogues and HIV suppression in vitro.
Topics: Anti-HIV Agents; HIV Infections; HIV-1; Humans; Reverse Transcriptase Inhibitors; Stavudine; Virus Replication; Zalcitabine; Zidovudine | 2000 |
Incidence of pancreatitis in HIV-infected patients receiving nucleoside reverse transcriptase inhibitor drugs.
Topics: Adult; Amylases; Anti-HIV Agents; Didanosine; Female; HIV Infections; HIV-1; Humans; Hydroxyurea; Incidence; Lipase; Longitudinal Studies; Male; Pancreatitis; Reverse Transcriptase Inhibitors; Stavudine; United States; Zidovudine | 2001 |
Differential incorporation and removal of antiviral deoxynucleotides by human DNA polymerase gamma.
Topics: Anti-HIV Agents; Cytidine Triphosphate; Deoxyguanine Nucleotides; Deoxyribonucleotides; Dideoxynucleotides; DNA; DNA Polymerase gamma; DNA Replication; DNA-Directed DNA Polymerase; Exodeoxyribonucleases; Humans; Kinetics; Lamivudine; Nucleic Acid Synthesis Inhibitors; Reverse Transcriptase Inhibitors; Stavudine; Substrate Specificity; Thymine Nucleotides; Zalcitabine; Zidovudine | 2001 |
Fatal portal hypertension, liver failure, and mitochondrial dysfunction after HIV-1 nucleoside analogue-induced hepatitis and lactic acidaemia.
Topics: Acute Disease; Aged; Anti-HIV Agents; Chemical and Drug Induced Liver Injury; Didanosine; Fatal Outcome; Fatty Liver; HIV Infections; HIV-1; Humans; Hypertension, Portal; Male; Mitochondria, Liver; Stavudine; Zidovudine | 2001 |
Treatment briefs.
Topics: CD4 Lymphocyte Count; Clinical Trials as Topic; Didanosine; Drug Industry; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Nerve Growth Factors; Nervous System Diseases; Pyridines; Recombinant Proteins; Stavudine; Zalcitabine; Zidovudine | 1995 |
What we know about anti-HIV drugs.
Topics: Antiviral Agents; Didanosine; DNA, Viral; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Lamivudine; RNA, Viral; Stavudine; Zalcitabine; Zidovudine | 1995 |
Combination treatment and single drugs: interview with Margaret Poscher, M.D. Interview by John S. James.
Topics: Acyclovir; Administration, Oral; Antiviral Agents; CD4 Lymphocyte Count; Didanosine; Drug Administration Schedule; Drug Resistance, Microbial; Drug Therapy, Combination; Ganciclovir; HIV Infections; Humans; Lamivudine; Stavudine; Zalcitabine; Zidovudine | 1995 |
New antiretroviral strategies: interview with Marcus Conant, M.D. Interview by John S. James.
Topics: Antiviral Agents; CD4 Lymphocyte Count; DNA, Viral; Drug Therapy, Combination; HIV; HIV Infections; Humans; Isoquinolines; Lamivudine; Peripheral Nervous System Diseases; Protease Inhibitors; Quinolines; Saquinavir; Stavudine; Zalcitabine; Zidovudine | 1995 |
Antiretroviral drug resistance.
Topics: Antiviral Agents; CD4 Lymphocyte Count; Didanosine; Drug Resistance, Microbial; Drug Resistance, Multiple; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Lamivudine; RNA, Viral; Stavudine; Viremia; Zalcitabine; Zidovudine | 1995 |
Update on clinical trials of combination therapies for HIV infection.
Topics: Adult; Antiviral Agents; CD4 Lymphocyte Count; Child; Clinical Trials as Topic; Didanosine; Drug Therapy, Combination; HIV Infections; Humans; Hydroxyurea; Lamivudine; RNA-Directed DNA Polymerase; Stavudine; Zalcitabine; Zidovudine | 1995 |
FDA triple header. Food and Drug Administration.
Topics: Acquired Immunodeficiency Syndrome; Adult; Antiviral Agents; CD4 Lymphocyte Count; Child; Didanosine; Drug Resistance, Microbial; Drug Therapy, Combination; HIV Protease Inhibitors; Humans; Isoquinolines; Lamivudine; Mutation; Quinolines; Salvage Therapy; Saquinavir; Stavudine; United States; United States Food and Drug Administration; Zalcitabine; Zidovudine | 1995 |
Combination therapy increases survival.
Topics: Antiviral Agents; CD4 Lymphocyte Count; Clinical Trials as Topic; Didanosine; Drug Therapy, Combination; HIV Infections; Humans; Lamivudine; Stavudine; Zalcitabine; Zidovudine | 1995 |
Back to the nukes.
Topics: Antiviral Agents; CD4 Lymphocyte Count; Clinical Trials as Topic; Didanosine; Drug Therapy, Combination; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Stavudine; Zalcitabine; Zidovudine | 1996 |
Update on other antivirals.
Topics: Adenine; Antiviral Agents; Didanosine; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Organophosphonates; Stavudine; Zalcitabine; Zidovudine | 1996 |
Nipping HIV in the bud.
Topics: Antiviral Agents; CD4 Lymphocyte Count; Didanosine; DNA, Viral; Drug Resistance, Microbial; Drug Therapy, Combination; HIV; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Isoquinolines; Lamivudine; Pyridines; Quinolines; Ritonavir; Saquinavir; Stavudine; Thiazoles; Valine; Virus Replication; Zalcitabine; Zidovudine | 1996 |
Antiviral roundup.
Topics: CD4 Lymphocyte Count; Cohort Studies; Delavirdine; Didanosine; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; HIV Reverse Transcriptase; HIV-1; Humans; Indoles; Mutation; Piperazines; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Stavudine; Zidovudine | 1996 |
Top AIDS researchers' strategy for antiretroviral treatment.
Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; CD4 Lymphocyte Count; Didanosine; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Patient Compliance; Practice Guidelines as Topic; RNA, Viral; Stavudine; Zalcitabine; Zidovudine | 1996 |
A patient's guide to protease inhibitors.
Topics: Anti-HIV Agents; Didanosine; Drug Administration Schedule; Drug Therapy, Combination; Eating; Guidelines as Topic; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Ritonavir; Saquinavir; Stavudine; Zidovudine | 1996 |
ddI and d4T plus protease inhibitors.
Topics: Anti-HIV Agents; Didanosine; HIV Infections; Humans; Lamivudine; Stavudine; Zalcitabine; Zidovudine | 1996 |
d4T+AZT--unexpected CD4 drop seen in study.
Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; CD4 Lymphocyte Count; Drug Therapy, Combination; Humans; Practice Patterns, Physicians'; Stavudine; Zidovudine | 1996 |
Dethroning AZT.
Topics: Alkynes; Anti-HIV Agents; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; Didanosine; Drug Therapy, Combination; HIV Infections; Humans; Hydroxyurea; Lamivudine; Oxazines; Stavudine; Viral Load; Zidovudine | 1997 |
Study shows three drugs better than two.
Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Clinical Trials as Topic; Disease Progression; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Stavudine; United States; Zidovudine | 1997 |
AZT, d4T ok'd for infants.
Topics: Administration, Oral; Animals; Anti-HIV Agents; Child; Child, Preschool; Female; HIV Infections; Humans; Infant; Infant, Newborn; Infectious Disease Transmission, Vertical; Mice; Pregnancy; Stavudine; Vaginal Neoplasms; Zidovudine | 1997 |
Nelfinavir - major trial results at retroviruses conference.
Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Clinical Trials as Topic; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; Humans; Isoquinolines; Lamivudine; Nelfinavir; Stavudine; Sulfonic Acids; Viral Load; Zidovudine | 1997 |
Spring cleaning in trial land.
Topics: Anti-HIV Agents; Brazil; CD4 Lymphocyte Count; Clinical Trials as Topic; Disease Progression; Drug Resistance, Microbial; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Saquinavir; Stavudine; United States; Viral Load; Zidovudine | 1997 |
Treating a survivor.
Topics: Acquired Immunodeficiency Syndrome; Adult; Anti-HIV Agents; Counseling; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Male; Mycobacterium avium-intracellulare Infection; Pneumonia, Pneumocystis; Reverse Transcriptase Inhibitors; Stavudine; Treatment Outcome; Zidovudine | 1997 |
3-drug therapy reduces deaths and new AIDS-related illnesses by 50%.
Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Reverse Transcriptase Inhibitors; Stavudine; Zidovudine | 1997 |
HIV in the brain: an interview with Dr. Michael Wool, UCLA researcher.
Topics: AIDS Dementia Complex; Anti-HIV Agents; Blood-Brain Barrier; Brain; Drug Therapy, Combination; Drugs, Investigational; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Nevirapine; Reverse Transcriptase Inhibitors; Stavudine; Viral Load; Zidovudine | 1998 |
ACTG 343: three drugs better than two for maintaining HIV suppression.
Topics: AIDS Vaccines; Anti-HIV Agents; CD4 Lymphocyte Count; Clinical Trials as Topic; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Reverse Transcriptase Inhibitors; Saquinavir; Stavudine; Viral Load; Zidovudine | 1998 |
Drug research shows easier dosing, new combinations are making gains.
Topics: Anti-HIV Agents; Clinical Trials as Topic; Drug Combinations; Drug Therapy; Drug Therapy, Combination; Enzyme Inhibitors; HIV Infections; HIV Protease Inhibitors; Humans; Hydroxyurea; Salvage Therapy; Stavudine; United States; Zidovudine | 1998 |
Reevaluating initial therapy.
Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Clinical Trials as Topic; Didanosine; DNA, Viral; Drug Resistance, Microbial; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; Humans; Lamivudine; Polymerase Chain Reaction; Stavudine; Viral Load; Zidovudine | 1998 |
New study shows efavirenz effective with d4T and 3TC.
Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Cerebrospinal Fluid; Clinical Trials as Topic; Cyclopropanes; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Male; Oxazines; Reverse Transcriptase Inhibitors; Stavudine; Vagina; Viral Load; Zidovudine | 1999 |
Antiretroviral therapy for adults and children.
Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Child; Didanosine; Female; HIV Infections; Humans; Pregnancy; Pregnancy Complications, Infectious; Primary Health Care; Stavudine; Viral Load; Zalcitabine; Zidovudine | 1995 |
[A rare etiology of hepatic steatosis associated with lactic acidosis: the toxicity of antiviral nucleoside analogues].
Topics: Acidosis, Lactic; Adult; Anti-HIV Agents; Antimetabolites; Didanosine; Fatal Outcome; Fatty Liver; Female; HIV Seropositivity; Humans; Lamivudine; Microscopy, Electron; Mitochondria, Liver; Stavudine; Zidovudine | 2001 |
R211K and L214F do not invariably confer high level phenotypic resistance to thymidine analogs in zidovudine-naive patients with M184V.
Topics: Anti-HIV Agents; Drug Resistance, Microbial; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Microbial Sensitivity Tests; Mutation; Phenotype; Reverse Transcriptase Inhibitors; Stavudine; Zidovudine | 2001 |
Choosing which nuke to use first.
Topics: Didanosine; Dideoxynucleosides; Drug Administration Schedule; HIV Infections; Humans; Lamivudine; Reverse Transcriptase Inhibitors; Stavudine; Zidovudine | 2001 |
Selection by AZT and rapid replacement in the absence of drugs of HIV type 1 resistant to multiple nucleoside analogs.
Topics: Amino Acid Sequence; Anti-HIV Agents; Base Sequence; DNA, Viral; Drug Resistance, Microbial; Drug Resistance, Multiple; Evolution, Molecular; Genetic Heterogeneity; HIV Infections; HIV Protease Inhibitors; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Molecular Sequence Data; Mutagenesis, Insertional; Phylogeny; Reverse Transcriptase Inhibitors; Saquinavir; Stavudine; Time Factors; Zidovudine | 2001 |
Stavudine versus zidovudine and the development of lipodystrophy.
Topics: Adult; Age Factors; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Cholesterol; Cohort Studies; Female; HIV Infections; Humans; Lipodystrophy; Male; Odds Ratio; Prevalence; Regression Analysis; Risk Factors; Stavudine; Viral Load; White People; Zidovudine | 2001 |
Thymidine analog and multinucleoside resistance mutations are associated with decreased phenotypic susceptibility to stavudine in HIV type 1 isolated from zidovudine-naive patients experiencing viremia on stavudine-containing regimens.
Topics: Anti-HIV Agents; Drug Resistance, Microbial; Drug Resistance, Multiple; Drug Therapy, Combination; HIV Infections; HIV Protease; HIV Reverse Transcriptase; HIV-1; Humans; Microbial Sensitivity Tests; Molecular Sequence Data; Mutation; Reverse Transcriptase Inhibitors; RNA, Viral; Stavudine; Thymidine; Viremia; Zidovudine | 2001 |
Differential susceptibility of retroviruses to nucleoside analogues.
Topics: Animals; Antiviral Agents; Cell Line; Cricetinae; Didanosine; Dose-Response Relationship, Drug; Humans; Inhibitory Concentration 50; Lamivudine; Mink; Nucleosides; Retroviridae; Reverse Transcriptase Inhibitors; Stavudine; Substrate Specificity; Zalcitabine; Zidovudine | 2001 |
Synthesis of 5-alkenylated D4T analogues via the Pd-catalyzed cross-coupling reaction.
Topics: Catalysis; Cell Line; Chromatography, Thin Layer; HIV-1; Humans; Magnetic Resonance Spectroscopy; Palladium; RNA-Directed DNA Polymerase; Spectroscopy, Fourier Transform Infrared; Stavudine; Uridine; Zidovudine | 2001 |
Low frequency of severe hepatotoxicity and association with HCV coinfection in HIV-positive patients treated with HAART.
Topics: Alanine Transaminase; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Cohort Studies; Disease Progression; Female; Hepatitis B Surface Antigens; Hepatitis C; HIV Seropositivity; HIV-1; Humans; Male; Proportional Hazards Models; Stavudine; Zidovudine | 2001 |
Inhibition of purified recombinant reverse transcriptase from wild-type and zidovudine-resistant clinical isolates of human immunodeficiency virus type 1 by zidovudine, stavudine, and lamivudine triphosphates.
Topics: Anti-HIV Agents; Cytidine Triphosphate; Dideoxynucleotides; Dose-Response Relationship, Drug; Drug Resistance, Microbial; Escherichia coli; HIV Infections; HIV-1; Lamivudine; Recombinant Proteins; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Stavudine; Thymine Nucleotides; Transfection; Zidovudine | 2001 |
Hyperlactatemia and antiretroviral therapy: the Swiss HIV Cohort Study.
Topics: Acidosis, Lactic; Adult; Anti-HIV Agents; Cohort Studies; Didanosine; Female; HIV Infections; Humans; Male; Prevalence; Reverse Transcriptase Inhibitors; Risk Factors; Stavudine; Switzerland; Zidovudine | 2001 |
Increased ability for selection of zidovudine resistance in a distinct class of wild-type HIV-1 from drug-naive persons.
Topics: Anti-HIV Agents; Base Sequence; Didanosine; Dideoxynucleosides; DNA, Viral; Drug Resistance, Viral; Evolution, Molecular; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Molecular Sequence Data; Mutagenesis; Recombination, Genetic; Reverse Transcriptase Inhibitors; Stavudine; Virus Replication; Zalcitabine; Zidovudine | 2001 |
Drugs for HIV infection.
Topics: Alkynes; Benzoxazines; Cyclopropanes; Delavirdine; Didanosine; Dose-Response Relationship, Drug; HIV Infections; HIV Protease Inhibitors; Humans; Nelfinavir; Nevirapine; Oxazines; Reverse Transcriptase Inhibitors; Saquinavir; Stavudine; Zidovudine | 2001 |
Phenotypic and genotypic resistance to nucleoside reverse transcriptase inhibitors in HIV-1 clinical isolates.
Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; DNA, Viral; Drug Resistance, Viral; Female; Genotype; HIV Infections; HIV-1; Humans; Male; Microbial Sensitivity Tests; Mutation; Patient Selection; Phenotype; Polymerase Chain Reaction; Reverse Transcriptase Inhibitors; RNA, Viral; Stavudine; Time Factors; Treatment Failure; Viral Load; Zidovudine | 2001 |
Use of highly active antiretroviral therapy in a cohort of HIV-seropositive women.
Topics: Adolescent; Adult; Age Factors; Aged; Antiretroviral Therapy, Highly Active; Clinical Trials as Topic; Cohort Studies; Education; Female; HIV Protease Inhibitors; HIV Seropositivity; Humans; Logistic Models; Middle Aged; Reverse Transcriptase Inhibitors; Stavudine; Time Factors; Zidovudine | 2002 |
Low-rate emergence of thymidine analogue mutations and multi-drug resistance mutations in the HIV-1 reverse transcriptase gene in therapy-naive patients receiving stavudine plus lamivudine combination therapy.
Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Drug Resistance, Multiple, Viral; Drug Therapy, Combination; Genotype; HIV Reverse Transcriptase; Humans; Lamivudine; Mutation; Stavudine; Viral Load; Zidovudine | 2001 |
Clinical trials group: two studies are now open to patients who qualify.
Topics: Alkynes; Benzoxazines; CD4 Lymphocyte Count; Clinical Trials as Topic; Cyclopropanes; Drug Therapy, Combination; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Oxazines; Patient Selection; Reverse Transcriptase Inhibitors; Ritonavir; Stavudine; Viral Load; Zidovudine | 2000 |
Azidodeoxythymidine and didehydrodeoxythymidine as inhibitors and substrates of the human herpesvirus 8 thymidine kinase.
Topics: Amino Acid Sequence; Anti-HIV Agents; Catalytic Domain; Enzyme Inhibitors; Herpesvirus 8, Human; Humans; Kinetics; Male; Molecular Sequence Data; Phosphorylation; Recombinant Proteins; Stavudine; Substrate Specificity; Thymidine Kinase; Zidovudine | 2002 |
Determination of some anti-human immunodeficiency virus nucleosides by capillary zone electrophoresis-tandem mass spectrometry.
Topics: Anti-HIV Agents; Electrophoresis, Capillary; Hydrogen-Ion Concentration; Nucleosides; Osmolar Concentration; Reference Standards; Reverse Transcriptase Inhibitors; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Stavudine; Zidovudine | 2002 |
Resistance to antiretroviral treatment in Gabon: need for implementation of guidelines on antiretroviral therapy use and HIV-1 drug resistance monitoring in developing countries.
Topics: Anti-HIV Agents; Developing Countries; Didanosine; Drug Resistance, Viral; Gabon; HIV Infections; HIV Protease; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Population Surveillance; Practice Guidelines as Topic; Reverse Transcriptase Inhibitors; Stavudine; Zidovudine | 2002 |
An APE that proofreads.
Topics: Anti-HIV Agents; Carbon-Oxygen Lyases; DNA; DNA Repair; DNA-(Apurinic or Apyrimidinic Site) Lyase; DNA, Viral; Escherichia coli; HIV; Humans; Stavudine; Substrate Specificity; Zidovudine | 2002 |
An exonucleolytic activity of human apurinic/apyrimidinic endonuclease on 3' mispaired DNA.
Topics: Anti-HIV Agents; Carbon-Oxygen Lyases; Cell Line; DNA; DNA Damage; DNA Repair; DNA-(Apurinic or Apyrimidinic Site) Lyase; Exodeoxyribonucleases; Humans; Reverse Transcriptase Inhibitors; Stavudine; Substrate Specificity; Zidovudine | 2002 |
Regression of HIV-associated pulmonary arterial hypertension and long-term survival during antiretroviral therapy.
Topics: Adult; Anti-HIV Agents; Anticoagulants; Drug Therapy, Combination; Echocardiography; Follow-Up Studies; HIV Infections; Humans; Hypertension, Pulmonary; Lamivudine; Male; Nelfinavir; Severity of Illness Index; Stavudine; Treatment Outcome; Zidovudine | 2001 |
Viral and immunologic follow up of 4 to 9 years of AIDS treatments by quadruple combinations of virostatics including integrase inhibitors applied in short sequences differing by drug rotation.
Topics: Acquired Immunodeficiency Syndrome; Acriflavine; Adult; Anti-HIV Agents; Antiviral Agents; CD4-CD8 Ratio; Didanosine; Drug Therapy, Combination; Ellipticines; Female; Follow-Up Studies; HIV-1; Humans; Integrase Inhibitors; Male; Middle Aged; Protease Inhibitors; Stavudine; Vitamin B 12; Zalcitabine; Zidovudine | 2002 |
Tenofovir exhibits low cytotoxicity in various human cell types: comparison with other nucleoside reverse transcriptase inhibitors.
Topics: Adenine; Anti-HIV Agents; Antigens, CD34; Cell Line; Didanosine; Dideoxynucleosides; Epithelial Cells; Hematopoietic Stem Cells; Humans; Kidney Tubules, Proximal; Liver; Muscle, Skeletal; Organophosphonates; Organophosphorus Compounds; Reverse Transcriptase Inhibitors; Stavudine; Tenofovir; Tumor Cells, Cultured; Zalcitabine; Zidovudine | 2002 |
Selection of zidovudine resistance mutations and escape of human immunodeficiency virus type 1 from antiretroviral pressure in stavudine-treated pediatric patients.
Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Child; Child, Preschool; Drug Resistance, Viral; HIV Reverse Transcriptase; HIV-1; Humans; Infant; Mutagenesis, Site-Directed; Mutation; RNA, Viral; Stavudine; Viral Load; Zidovudine | 2002 |
Simple rapid method for quantification of antiretrovirals by liquid chromatography-tandem mass-spectrometry.
Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Calibration; Chromatography, High Pressure Liquid; Cyclopropanes; Drug Evaluation; Gas Chromatography-Mass Spectrometry; Humans; Oxazines; Reproducibility of Results; Sensitivity and Specificity; Stavudine; Zidovudine | 2002 |
[Drug combination therapy for children infected with HIV/AIDS--own experience].
Topics: Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Child; Child, Preschool; Didanosine; Drug Resistance, Viral; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; Humans; Infant; Lamivudine; Male; Nelfinavir; Poland; Reverse Transcriptase Inhibitors; Stavudine; Treatment Outcome; Viral Load; Zidovudine | 2001 |
ATP-dependent removal of nucleoside reverse transcriptase inhibitors by human immunodeficiency virus type 1 reverse transcriptase.
Topics: Adenine; Adenosine Triphosphate; Anti-HIV Agents; Catalysis; Drug Resistance, Viral; HIV Reverse Transcriptase; Mutation; Organophosphonates; Organophosphorus Compounds; Recombinant Proteins; Reverse Transcriptase Inhibitors; Stavudine; Tenofovir; Virus Replication; Zidovudine | 2002 |
[Mononucleosis syndrome with viro-immunologic parameters similar to those of a primary HIV-1 infection after interruption of highly effective anti-retroviral treatment].
Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4-CD8 Ratio; Depression; Didanosine; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Infectious Mononucleosis; Male; Reverse Transcriptase Inhibitors; Ritonavir; Stavudine; Treatment Refusal; Trimethoprim, Sulfamethoxazole Drug Combination; Viral Load; Viremia; Zalcitabine; Zidovudine | 2002 |
Immunophenotypic analyses of CD34(+) cell subsets in bone marrow from HIV-infected patients during highly- active antiretroviral therapy.
Topics: Adult; Antigens, CD34; Antiretroviral Therapy, Highly Active; beta 2-Microglobulin; Bone Marrow Cells; Case-Control Studies; Female; Flow Cytometry; HIV Infections; HIV Protease Inhibitors; Humans; Immunoglobulin G; Immunophenotyping; Indinavir; Lamivudine; Leukocyte Count; Male; Middle Aged; Stavudine; T-Lymphocyte Subsets; Zidovudine | 2002 |
M184V is associated with a low incidence of thymidine analogue mutations and low phenotypic resistance to zidovudine and stavudine.
Topics: Drug Resistance, Microbial; Genotype; HIV Infections; HIV-1; Humans; Mutation; Phenotype; Retrospective Studies; Reverse Transcriptase Inhibitors; Stavudine; Thymidine; Viral Load; Zidovudine | 2002 |
Selection of a T-cell line resistant to stavudine and zidovudine by prolonged treatment with stavudine.
Topics: Anti-HIV Agents; Cell Line; Drug Resistance, Viral; HIV; Humans; Phosphorylation; RNA, Messenger; Stavudine; T-Lymphocytes; Thymidine Kinase; Time Factors; Zidovudine | 2002 |
[Cytomegalovirus retinitis after highly active antiretroviral therapy: a case report].
Topics: Adult; AIDS-Related Opportunistic Infections; Antiretroviral Therapy, Highly Active; Antiviral Agents; CD4 Lymphocyte Count; Cytomegalovirus Retinitis; Didanosine; Ganciclovir; HIV Infections; HIV Protease Inhibitors; Humans; Lamivudine; Male; Retinal Hemorrhage; Reverse Transcriptase Inhibitors; Risk; Saquinavir; Stavudine; Substance Abuse, Intravenous; Zidovudine | 2002 |
Stampidine is a potent inhibitor of Zidovudine- and nucleoside analog reverse transcriptase inhibitor-resistant primary clinical human immunodeficiency virus type 1 isolates with thymidine analog mutations.
Topics: Anti-HIV Agents; Dideoxynucleotides; Drug Resistance, Viral; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Nucleosides; Phenotype; Reverse Transcriptase Inhibitors; Stavudine; Structure-Activity Relationship; Thymidine; Thymidine Monophosphate; Zidovudine | 2002 |
Nucleoside reverse transcriptase inhibitors impair endothelium-dependent relaxation by increasing superoxide.
Topics: 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt; Animals; Aorta; Cells, Cultured; Dose-Response Relationship, Drug; Electron Spin Resonance Spectroscopy; Endothelium, Vascular; Free Radical Scavengers; In Vitro Techniques; Male; Mice; Mice, Inbred Strains; Nucleosides; Reverse Transcriptase Inhibitors; Stavudine; Superoxides; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents; Zidovudine | 2002 |
HIV-associated lipodystrophy syndrome: LioN-HAART cohort: (lipodystrophy in patients on nucleoside-based HAART). Highly active antiretroviral therapy.
Topics: Adult; Age Factors; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Clinical Trials as Topic; Cohort Studies; HIV-Associated Lipodystrophy Syndrome; Humans; Male; Prospective Studies; Reverse Transcriptase Inhibitors; Risk Factors; Stavudine; Time Factors; Zidovudine | 2002 |
Macrocytosis as an indicator of medication (zidovudine) adherence in patients with HIV infection.
Topics: Adult; Anemia, Macrocytic; Anti-HIV Agents; Case-Control Studies; Chi-Square Distribution; Erythrocyte Indices; Female; HIV Infections; Humans; Incidence; Male; Patient Compliance; Retrospective Studies; Stavudine; Treatment Outcome; Zidovudine | 2002 |
One-pot synthesis of hydrogen phosphonate derivatives of d4T and AZT.
Topics: Anti-HIV Agents; Humans; Organophosphonates; Prodrugs; Stavudine; Zidovudine | 2002 |
Mean cell volume (MCV) changes in HIV-positive patients taking nucleoside reverse transcriptase inhibitors (NRTIs): a surrogate marker for adherence.
Topics: Biomarkers; Erythrocyte Indices; HIV Infections; Humans; Lamivudine; Patient Compliance; Retrospective Studies; Reverse Transcriptase Inhibitors; Stavudine; Treatment Outcome; Zidovudine | 2002 |
Synthesis and anti-HIV activity of [d4U]-[trovirdine analogue] and [d4T]-[trovirdine analogue] heterodimers as inhibitors of HIV-1 reverse transcriptase.
Topics: Anti-HIV Agents; Dideoxynucleosides; Dimerization; Drug Evaluation, Preclinical; HIV Reverse Transcriptase; HIV-1; Humans; Lymphocytes; Pyridines; Reverse Transcriptase Inhibitors; Stavudine; Tumor Cells, Cultured; Zidovudine | 2002 |
Impact of stavudine phenotype and thymidine analogues mutations on viral response to stavudine plus lamivudine in ALTIS 2 ANRS trial.
Topics: Adult; Anti-HIV Agents; Drug Resistance, Viral; Female; Genotype; HIV Infections; HIV-1; Humans; Inhibitory Concentration 50; Lamivudine; Male; Middle Aged; Molecular Sequence Data; Mutation; Phenotype; RNA, Viral; Stavudine; Zidovudine | 2002 |
Fat wasting--AZT vs. d4T.
Topics: HIV Infections; HIV Wasting Syndrome; Humans; Male; Reverse Transcriptase Inhibitors; Stavudine; Zidovudine | 2002 |
Multiple relapses of human cytomegalovirus retinitis during HAART in an AIDS patient with reconstitution of CD4+ T cell count in the absence of HCMV-specific CD4+ T cell response.
Topics: Adult; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Antiviral Agents; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; Cytomegalovirus Retinitis; Didanosine; Follow-Up Studies; Ganciclovir; HIV Protease Inhibitors; Humans; Lamivudine; Lymphocyte Activation; Male; Nevirapine; Recurrence; Reverse Transcriptase Inhibitors; Stavudine; Zidovudine | 2003 |
Significant levels of intracellular stavudine triphosphate are found in HIV-infected zidovudine-treated patients.
Topics: Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Chromatography, High Pressure Liquid; HIV Infections; Humans; Intracellular Fluid; Leukocytes, Mononuclear; Mass Spectrometry; Stavudine; Zidovudine | 2003 |
Nevirapine resistance mutation at codon 181 of the HIV-1 reverse transcriptase confers stavudine resistance by increasing nucleotide substrate discrimination and phosphorolytic activity.
Topics: Codon; Drug Resistance, Viral; HIV Reverse Transcriptase; Mutation; Nevirapine; Nucleotides; Phosphorylation; Reverse Transcriptase Inhibitors; Stavudine; Zidovudine | 2003 |
New questions about an old combination--ddI + d4T.
Topics: Didanosine; Drug Therapy, Combination; HIV Infections; Humans; Reverse Transcriptase Inhibitors; Stavudine; Zidovudine | 2003 |
Acute hepatic failure and lactate acidosis associated with antiretroviral treatment for HIV.
Topics: Acidosis, Lactic; Acute Disease; Adult; Anti-HIV Agents; Biopsy; Critical Care; Didanosine; Drug Therapy, Combination; Female; Follow-Up Studies; HIV Infections; Humans; Liver; Liver Failure; Pancreatitis; Reverse Transcriptase Inhibitors; Stavudine; Time Factors; Tomography, X-Ray Computed; Treatment Outcome; Ultrasonography; Zidovudine | 2003 |
A novel genetic pathway of human immunodeficiency virus type 1 resistance to stavudine mediated by the K65R mutation.
Topics: Anti-HIV Agents; Cell Line; Drug Resistance, Viral; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Microbial Sensitivity Tests; Mutation; Reverse Transcriptase Inhibitors; Stavudine; Virus Cultivation; Zidovudine | 2003 |
Structural determinants in human DNA polymerase gamma account for mitochondrial toxicity from nucleoside analogs.
Topics: Amino Acid Sequence; Anti-HIV Agents; Baculoviridae; Binding Sites; DNA Polymerase gamma; DNA Primers; DNA-Directed DNA Polymerase; DNA, Viral; Electrophoretic Mobility Shift Assay; Humans; Lamivudine; Mitochondria; Molecular Sequence Data; Mutagenesis, Site-Directed; Polymerase Chain Reaction; Protein Conformation; Protein Folding; Recombinant Fusion Proteins; Reverse Transcriptase Inhibitors; Sequence Homology, Amino Acid; Stavudine; Zalcitabine; Zidovudine | 2003 |
[Measuring the HIV viral load with LCx (Abbott): importance for the therapeutic follow-up of 3 patients infected by type O HIV].
Topics: Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Cyclopropanes; Drug Resistance, Multiple, Viral; Female; Follow-Up Studies; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Indinavir; Lamivudine; Male; Oxazines; Polymerase Chain Reaction; Reverse Transcriptase Inhibitors; Ritonavir; Stavudine; Viral Load; Viremia; Zidovudine | 2003 |
Use of HIV-1 reverse transcriptase recovered from human plasma for phenotypic drug susceptibility testing.
Topics: Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Dideoxynucleotides; Drug Resistance, Viral; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Microbial Sensitivity Tests; Reproducibility of Results; Stavudine; Thymine Nucleotides; Virion; Zidovudine | 2003 |
[Observational study on the efficacy of the application of two classical regimens of triple antiretroviral therapy].
Topics: Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Cohort Studies; Didanosine; Drug Evaluation; Female; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Male; Retrospective Studies; Reverse Transcriptase Inhibitors; Stavudine; Time Factors; Treatment Outcome; Viral Load; Zidovudine | 2003 |
Nevirapine-based fixed-dose combination ARVs.
Topics: Dose-Response Relationship, Drug; Drug Eruptions; Drug Therapy, Combination; HIV Infections; Humans; Nevirapine; Patient Compliance; Reverse Transcriptase Inhibitors; Stavudine; Zidovudine | 2003 |
Susceptibility of human T cell leukemia virus type I to nucleoside reverse transcriptase inhibitors.
Topics: Adenine; Cell Line; Dideoxynucleosides; Human T-lymphotropic virus 1; Humans; Lamivudine; Microbial Sensitivity Tests; Organophosphonates; Organophosphorus Compounds; Reverse Transcriptase Inhibitors; Stavudine; Tenofovir; Virus Replication; Zalcitabine; Zidovudine | 2003 |
Fat distribution and metabolic abnormalities in HIV-infected patients on first combination antiretroviral therapy including stavudine or zidovudine: role of physical activity as a protective factor.
Topics: Adult; Anthropometry; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Body Composition; Exercise; Female; HIV Infections; HIV-1; HIV-Associated Lipodystrophy Syndrome; Humans; Male; Middle Aged; Reverse Transcriptase Inhibitors; Stavudine; Zidovudine | 2003 |
The prevalence of reduced zidovudine susceptibility in zidovudine-naive, antiretroviral-experienced HIV-1-infected patients.
Topics: Anti-HIV Agents; Drug Resistance, Multiple; Drug Resistance, Viral; Drug Therapy, Combination; HIV Infections; Humans; Mutation; Reverse Transcriptase Inhibitors; Stavudine; Zidovudine | 2003 |
Safety and efficacy of switching to alternative nucleoside analogues following symptomatic hyperlactatemia and lactic acidosis.
Topics: Acidosis, Lactic; Adult; Alanine Transaminase; Didanosine; Dideoxynucleosides; Drug Therapy, Combination; Female; HIV Infections; Humans; Lactates; Lamivudine; Male; Middle Aged; Reverse Transcriptase Inhibitors; Stavudine; Time Factors; Zidovudine | 2003 |
Molecular characterization of thymidine kinase from Ureaplasma urealyticum: nucleoside analogues as potent inhibitors of mycoplasma growth.
Topics: Amino Acid Sequence; Cell Division; Cloning, Molecular; Deoxyuridine; Escherichia coli; Feedback, Physiological; Molecular Sequence Data; Molecular Weight; Mycoplasma pneumoniae; Nucleosides; Phosphates; Pyrimidine Nucleosides; Recombinant Proteins; Sequence Homology, Amino Acid; Stavudine; Substrate Specificity; Tetrahydrouridine; Thymidine; Thymidine Kinase; Thymine Nucleotides; Ureaplasma urealyticum; Zidovudine | 2003 |
Thymidine analogue reverse transcriptase inhibitors resistance mutations profiles and association to other nucleoside reverse transcriptase inhibitors resistance mutations observed in the context of virological failure.
Topics: Anti-HIV Agents; Base Sequence; Drug Resistance, Viral; Drug Therapy, Combination; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Mutation; Reverse Transcriptase Inhibitors; RNA, Viral; Stavudine; Thymidine; Treatment Failure; Viral Load; Zidovudine | 2004 |
Intracellular disposition and metabolic effects of zidovudine, stavudine and four protease inhibitors in cultured adipocytes.
Topics: Adipocytes; Animals; Anti-HIV Agents; Cell Differentiation; Cell Survival; Cells, Cultured; HIV Protease Inhibitors; Lipolysis; Mice; Phosphorylation; Reverse Transcriptase Inhibitors; Stavudine; Zidovudine | 2003 |
Host factors may be more important than choice of antiretrovirals in the development of lipoatrophy.
Topics: Adolescent; Adult; Aged; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Female; HIV Infections; HIV-Associated Lipodystrophy Syndrome; Humans; Integration Host Factors; Leptin; Male; Middle Aged; Retrospective Studies; Stavudine; Zidovudine | 2003 |
Serum L-lactate and pyruvate in HIV-infected patients with and without presumed NRTI-related adverse events compared to healthy volunteers.
Topics: Adult; Anti-HIV Agents; DNA, Mitochondrial; Female; HIV Infections; HIV-1; Humans; Lactic Acid; Male; Mitochondria; Pyruvic Acid; Reverse Transcriptase Inhibitors; Stavudine; Zidovudine | 2004 |
Synthesis and electrospray ionization mass spectra of AZT/d4T boranophosphates.
Topics: Anti-HIV Agents; Boranes; Phosphates; Phosphorylation; Spectrometry, Mass, Electrospray Ionization; Stavudine; Zidovudine | 2004 |
Efficacy and safety of ritonavir/indinavir 100/400 mg twice daily in combination with two nucleoside analogues in antiretroviral treatment-naive HIV-infected individuals.
Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Didanosine; Drug Administration Schedule; Drug Therapy, Combination; Female; HIV Infections; Humans; Indinavir; Lamivudine; Male; Middle Aged; Prospective Studies; Ritonavir; Stavudine; Zidovudine | 2003 |
In vitro activity of stampidine against primary clinical human immunodeficiency virus isolates.
Topics: Cells, Cultured; Dideoxynucleotides; Drug Resistance, Viral; Genotype; HIV; HIV Infections; HIV-1; Humans; Lamivudine; Mutation; Neutrophils; Phenotype; Reverse Transcriptase Inhibitors; Stavudine; Thymidine Monophosphate; Viral Plaque Assay; Zidovudine | 2004 |
Can the peripheral blood monocyte count be used as a marker of CSF resistance to antiretroviral drugs?
Topics: Anti-HIV Agents; Biomarkers; Buffers; Culture Media; Dideoxynucleosides; Drug Resistance, Viral; HIV; HIV Infections; Humans; In Vitro Techniques; Leukocyte Count; Monocytes; Stavudine; Zidovudine | 2004 |
[Long-term tolerance. Preventing lipoatrophy].
Topics: Acquired Immunodeficiency Syndrome; Antiretroviral Therapy, Highly Active; Clinical Trials as Topic; Dideoxynucleosides; DNA, Mitochondrial; Drug Combinations; HIV-Associated Lipodystrophy Syndrome; Humans; Lamivudine; Long-Term Care; Risk Factors; Stavudine; Zidovudine | 2003 |
Disease progression in HIV-infected patients treated with stavudine vs. zidovudine.
Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Databases, Factual; Disease Progression; Disease-Free Survival; Follow-Up Studies; HIV Infections; HIV Wasting Syndrome; Humans; Proportional Hazards Models; Prospective Studies; Reverse Transcriptase Inhibitors; Stavudine; Zidovudine | 2004 |
Molecular determinants of multi-nucleoside analogue resistance in HIV-1 reverse transcriptases containing a dipeptide insertion in the fingers subdomain: effect of mutations D67N and T215Y on removal of thymidine nucleotide analogues from blocked DNA prim
Topics: Adenosine Triphosphate; Amino Acid Sequence; Base Sequence; Codon; DNA; DNA Primers; Drug Resistance, Viral; Gene Deletion; HIV Reverse Transcriptase; Kinetics; Models, Molecular; Molecular Sequence Data; Mutation; Peptides; Phenotype; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Reverse Transcriptase Inhibitors; Sequence Homology, Amino Acid; Stavudine; Thymidine; Time Factors; Tyrosine; Zidovudine | 2004 |
Phenyl phosphoramidate derivatives of stavudine as anti-HIV agents with potent and selective in-vitro antiviral activity against adenovirus.
Topics: Adenoviridae; Adenoviridae Infections; Amides; Anti-HIV Agents; Antiviral Agents; Enzyme Inhibitors; HIV Infections; HIV-1; Humans; In Vitro Techniques; Phosphoric Acids; Stavudine; Structure-Activity Relationship; Zidovudine | 2004 |
Detection of stavudine concentrations in plasma of HIV-infected patients taking zidovudine.
Topics: Anti-HIV Agents; Drug Monitoring; HIV Infections; Humans; Stavudine; Zidovudine | 2004 |
Lamivudine 300 mg in HIV infection: dose change. Once-a-day dosing.
Topics: Adult; Child; Drug Therapy, Combination; France; HIV Infections; Humans; Indinavir; Lamivudine; Nelfinavir; Protease Inhibitors; Reverse Transcriptase Inhibitors; Stavudine; Zidovudine | 2004 |
Mechanistic explanation to the variable degradation behaviour of stavudine and zidovudine under hydrolytic, oxidative and photolytic conditions.
Topics: Hydrolysis; Oxidation-Reduction; Photolysis; Stavudine; Zidovudine | 2004 |
Chemoenzymatic syntheses of homo- and heterodimers of AZT and d4T, and evaluation of their anti-HIV activity.
Topics: Anti-HIV Agents; Cell Line; Dimerization; Fungal Proteins; HIV Infections; HIV-1; HIV-2; Humans; Lipase; Stavudine; Virus Replication; Zidovudine | 2004 |
Suppression of human immunodeficiency virus replication in human brain tissue by nucleoside reverse transcriptase inhibitors.
Topics: AIDS Dementia Complex; Antiretroviral Therapy, Highly Active; Brain; Dideoxynucleosides; HIV-1; Humans; In Vitro Techniques; Reverse Transcriptase Inhibitors; Stavudine; Virus Replication; Zidovudine | 2004 |
Nucleoside analogue use before and during highly active antiretroviral therapy and virus load rebound.
Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Australia; Cohort Studies; Didanosine; Drug Administration Schedule; Europe; Female; HIV Infections; Humans; Lamivudine; Male; Proportional Hazards Models; Reverse Transcriptase Inhibitors; Stavudine; Time Factors; Viral Load; Zidovudine | 2004 |
Phenotypic impact of HIV reverse transcriptase M184I/V mutations in combination with single thymidine analog mutations on nucleoside reverse transcriptase inhibitor resistance.
Topics: Adenine; Algorithms; Anti-HIV Agents; Databases, Genetic; Didanosine; Dideoxynucleosides; Drug Resistance, Multiple, Viral; HIV; HIV Infections; Humans; Mutation; Organophosphonates; Organophosphorus Compounds; Phenotype; Reverse Transcriptase Inhibitors; Stavudine; Tenofovir; Thymidine; Zalcitabine; Zidovudine | 2004 |
Lack of reduction of thymidine kinase activity in stavudine-treated HIV-infected patients.
Topics: Anti-HIV Agents; HIV Infections; Humans; Leukocytes, Mononuclear; Stavudine; Thymidine Kinase; Zidovudine | 2004 |
Broad specificity of human phosphoglycerate kinase for antiviral nucleoside analogs.
Topics: Acyclovir; Antiviral Agents; Humans; Nucleoside-Diphosphate Kinase; Phosphoglycerate Kinase; Purine Nucleotides; Pyrimidine Nucleotides; Recombinant Proteins; Stavudine; Substrate Specificity; Zidovudine | 2004 |
Assessing the risk of birth defects associated with antiretroviral exposure during pregnancy.
Topics: Abnormalities, Drug-Induced; Anti-Retroviral Agents; Female; Gestational Age; Humans; Lamivudine; Maternal-Fetal Exchange; Nelfinavir; Nevirapine; Pregnancy; Pregnancy Outcome; Prospective Studies; Risk Factors; Stavudine; Zidovudine | 2004 |
Tenofovir: new indication. For first-line antiretroviral therapy: wait and see.
Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Controlled Clinical Trials as Topic; Didanosine; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Lamivudine; Reverse Transcriptase Inhibitors; Stavudine; Treatment Outcome; Zidovudine | 2004 |
Antiretroviral treatment. HIV infection in adults: better-defined first-line treatment.
Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Antiviral Agents; CD4 Lymphocyte Count; Clinical Trials as Topic; Dideoxynucleosides; Drug Resistance, Microbial; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; Humans; Lamivudine; Nelfinavir; Oligopeptides; Organophosphonates; Oxazines; Pregnancy; Pyrimidinones; Ritonavir; Stavudine; Sulfonamides; Treatment Outcome; Viral Load; Zidovudine | 2004 |
Effects of zidovudine, stavudine and beta-aminoisobutyric acid on lipid homeostasis in mice: possible role in human fat wasting.
Topics: Aminoisobutyric Acids; Animals; Anti-HIV Agents; Body Weight; Homeostasis; Lipid Metabolism; Lipodystrophy; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Reverse Transcriptase Inhibitors; Stavudine; Thinness; Zidovudine | 2004 |
The HIV-1 nucleoside reverse transcriptase inhibitors stavudine and zidovudine alter adipocyte functions in vitro.
Topics: 3T3-L1 Cells; Adenine; Adipocytes; Animals; Apoptosis; Cell Differentiation; Didanosine; Dideoxynucleosides; HIV-1; HIV-Associated Lipodystrophy Syndrome; Lamivudine; Lipid Metabolism; Mice; Mitochondria; Organophosphonates; Reverse Transcriptase Inhibitors; Stavudine; Tenofovir; Zidovudine | 2004 |
Synthesis, in vitro anticancer evaluation, and interference with cell cycle progression of N-phosphoamino acid esters of zidovudine and stavudine.
Topics: Antineoplastic Agents; Cell Cycle; Cell Line, Tumor; Humans; Organophosphonates; Phosphoamino Acids; Stavudine; Zidovudine | 2004 |
Drug resistance mutations in the nucleotide binding pocket of human immunodeficiency virus type 1 reverse transcriptase differentially affect the phosphorolysis-dependent primer unblocking activity in the presence of stavudine and zidovudine and its inhib
Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Drug Resistance, Viral; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Kinetics; Microbial Sensitivity Tests; Models, Molecular; Mutation; Nucleotides; Oxazines; Reverse Transcriptase Inhibitors; Stavudine; Zidovudine | 2005 |
Improvements in lipoatrophy, mitochondrial DNA levels and fat apoptosis after replacing stavudine with abacavir or zidovudine.
Topics: Adipocytes; Adipose Tissue; Adult; Apoptosis; Dideoxynucleosides; DNA, Mitochondrial; Electron Transport; Female; HIV-Associated Lipodystrophy Syndrome; Humans; Leukocytes, Mononuclear; Male; Middle Aged; Mitochondria; Muscle, Skeletal; Reverse Transcriptase Inhibitors; Stavudine; Zidovudine | 2005 |
Simultaneous determination of the HIV nucleoside analogue reverse transcriptase inhibitors lamivudine, didanosine, stavudine, zidovudine and abacavir in human plasma by reversed phase high performance liquid chromatography.
Topics: Anti-HIV Agents; Chromatography, High Pressure Liquid; Didanosine; Dideoxynucleosides; Drug Stability; HIV; HIV Infections; Humans; Lamivudine; Quality Control; Reproducibility of Results; Reverse Transcriptase Inhibitors; Sensitivity and Specificity; Spectrophotometry, Ultraviolet; Stavudine; Zidovudine | 2005 |
Increased adipocyte apoptosis in lipoatrophy improves within 48 weeks of switching patient therapy from Stavudine to abacavir or zidovudine.
Topics: Adipocytes; Adipose Tissue; Adult; Anti-HIV Agents; Apoptosis; Biopsy; Dideoxynucleosides; DNA; DNA Fragmentation; Female; HIV Infections; HIV-Associated Lipodystrophy Syndrome; Humans; In Situ Nick-End Labeling; Male; Middle Aged; Stavudine; Zidovudine | 2005 |
Changes in mitochondrial RNA production in cells treated with nucleoside analogues.
Topics: Antiviral Agents; Cell Line; Didanosine; DNA, Mitochondrial; Humans; Polymerase Chain Reaction; Reverse Transcriptase Inhibitors; RNA; RNA, Mitochondrial; Stavudine; U937 Cells; Zidovudine | 2005 |
The use of a triple nucleoside-nucleotide regimen for nonoccupational HIV post-exposure prophylaxis.
Topics: Adenine; Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Chi-Square Distribution; HIV Infections; Humans; Lamivudine; Male; Nelfinavir; Organophosphonates; Reverse Transcriptase Inhibitors; Risk Assessment; Risk-Taking; Stavudine; Tenofovir; Zidovudine | 2005 |
Suppression of multidrug-resistant HIV-1 reverse transcriptase primer unblocking activity by alpha-phosphate-modified thymidine analogues.
Topics: Adenosine Triphosphate; Boron Compounds; Dideoxynucleotides; Drug Resistance, Multiple, Viral; HIV-1; Humans; Kinetics; Mutation; Phosphorylation; RNA-Directed DNA Polymerase; Stavudine; Thymidine; Thymine Nucleotides; Time Factors; Zidovudine | 2005 |
Sculptra facial treatment: new physician locator.
Topics: Cosmetic Techniques; Humans; Lipodystrophy; Physicians; Referral and Consultation; Reverse Transcriptase Inhibitors; Stavudine; Zidovudine | 2005 |
In vitro anti-HIV potency of stampidine alone and in combination with standard anti-HIV drugs.
Topics: Anti-HIV Agents; Dideoxynucleotides; Drug Combinations; Drug Interactions; HIV-1; Humans; Lamivudine; Least-Squares Analysis; Models, Theoretical; Nelfinavir; Nevirapine; Phenotype; Stavudine; Thymidine Monophosphate; Virus Replication; Zidovudine | 2005 |
HIV leucoencephalopathy and TNFalpha expression in neurones.
Topics: Adult; AIDS Dementia Complex; Anti-Retroviral Agents; Basal Ganglia; Biopsy; Brain; Diffusion Magnetic Resonance Imaging; Disease Progression; Follow-Up Studies; Frontal Lobe; HIV Envelope Protein gp41; Humans; Macrophages; Male; Microglia; Middle Aged; Neurologic Examination; Neurons; Neuropsychological Tests; Saquinavir; Stavudine; Treatment Outcome; Tumor Necrosis Factor-alpha; Zidovudine | 2005 |
Effect of change in nucleoside structure on the activation and antiviral activity of phosphoramidate derivatives.
Topics: Amides; Animals; Anti-HIV Agents; Cell Line, Tumor; Dideoxynucleotides; Enzyme Inhibitors; Esterases; Humans; Kinetics; Lipase; Lymphocytes; Microbial Sensitivity Tests; Molecular Conformation; Peptide Hydrolases; Phenol; Phosphoric Acids; Stavudine; Stereoisomerism; Structure-Activity Relationship; Thymidine Monophosphate; Zidovudine | 2005 |
Oxygen consumption by cultured human cells is impaired by a nucleoside analogue cocktail that inhibits mitochondrial DNA synthesis.
Topics: Adipocytes; Cell Culture Techniques; Cell Line; Cell Respiration; DNA, Mitochondrial; Humans; Lipids; Models, Biological; Oxygen Consumption; Reverse Transcriptase Inhibitors; Stavudine; Zalcitabine; Zidovudine | 2005 |
The effect of long-term storage on measured plasma lactate concentrations and prospective lactate results from a multicenter trial of antiretroviral therapy.
Topics: Acidosis, Lactic; Anti-HIV Agents; Blood Preservation; Blood Specimen Collection; Didanosine; HIV Infections; Humans; Lactates; Lamivudine; Multicenter Studies as Topic; Oxalates; Randomized Controlled Trials as Topic; Reverse Transcriptase Inhibitors; Sodium Fluoride; Specimen Handling; Stavudine; Time Factors; Zidovudine | 2005 |
Homo and heterodimers of ddI, d4T and AZT: influence of (5'-5') thiolcabonate-carbamate linkage on anti-HIV activity.
Topics: Anti-HIV Agents; Antiviral Agents; Carbamates; Didanosine; Dimerization; HIV; HIV Infections; Models, Chemical; Molecular Conformation; Mutation; Stavudine; Sulfhydryl Compounds; Zidovudine | 2005 |
Assessment of adipokine expression and mitochondrial toxicity in HIV patients with lipoatrophy on stavudine- and zidovudine-containing regimens.
Topics: Adiponectin; Adipose Tissue; Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; DNA, Mitochondrial; Drug Therapy, Combination; HIV Infections; HIV-1; HIV-Associated Lipodystrophy Syndrome; Humans; Interleukin-6; Male; Middle Aged; Mitochondria; Reverse Transcriptase Inhibitors; Stavudine; Sterol Regulatory Element Binding Protein 1; Tumor Necrosis Factor-alpha; Zidovudine | 2005 |
Synthesis and anti-HIV activity of beta-D-3'-azido-2',3'-unsaturated nucleosides and beta-D-3'-azido-3'-deoxyribofuranosylnucleosides.
Topics: Anti-HIV Agents; Cells, Cultured; HIV-1; Humans; Leukocytes, Mononuclear; Reverse Transcriptase Inhibitors; Stavudine; Virus Replication; Xylose; Zidovudine | 2005 |
Lack of evidence for in vivo transformation of zidovudine triphosphate to stavudine triphosphate in human immunodeficiency virus-infected patients.
Topics: Anti-HIV Agents; Cell Line; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; HIV Infections; Humans; Kinetics; Leukocytes, Mononuclear; Mass Spectrometry; Microbial Sensitivity Tests; Stavudine; Time Factors; Zidovudine | 2006 |
Antiretroviral nucleosides, deoxynucleotide carrier and mitochondrial DNA: evidence supporting the DNA pol gamma hypothesis.
Topics: Animals; DNA; DNA, Mitochondrial; Echocardiography; Genes, pol; HIV Infections; HIV-1; Humans; Immunoblotting; Lamivudine; Membrane Transport Proteins; Mice; Mice, Transgenic; Microscopy, Electron, Transmission; Mitochondria, Heart; Mitochondrial Membrane Transport Proteins; Models, Molecular; Myocardium; Reverse Transcriptase Inhibitors; Reverse Transcriptase Polymerase Chain Reaction; Stavudine; Zidovudine | 2006 |
[In vitro selection and phenotyping of HIV-1 mutants resistant to azidothymidine and didanosine].
Topics: Didanosine; Drug Resistance, Viral; HIV-1; Mutation; Reverse Transcriptase Inhibitors; Stavudine; Thymidine; Zidovudine | 2005 |
Unrecognized near-fatal hyperlactatemia in an HIV-infected infant exposed to nucleoside reverse transcriptase inhibitors.
Topics: Anti-HIV Agents; Female; HIV Infections; Humans; Infant, Newborn; Lactates; Lamivudine; Male; Mitochondria; Nevirapine; Pregnancy; Pregnancy Complications, Infectious; Reverse Transcriptase Inhibitors; Stavudine; Zidovudine | 2007 |
Is stavudine triphosphate a natural metabolite of zidovudine?
Topics: Anti-HIV Agents; Chromatography, High Pressure Liquid; HIV Infections; Humans; Leukocytes, Mononuclear; Stavudine; Zidovudine | 2006 |
Changes in body composition and mitochondrial nucleic acid content in patients switched from failed nucleoside analogue therapy to ritonavir-boosted indinavir and efavirenz.
Topics: Absorptiometry, Photon; Acquired Immunodeficiency Syndrome; Adult; Body Composition; DNA, Mitochondrial; HIV Protease Inhibitors; Humans; Indinavir; Lumbar Vertebrae; Middle Aged; Mitochondria; Reverse Transcriptase Inhibitors; Ritonavir; RNA; RNA, Mitochondrial; RNA, Viral; Stavudine; Tomography, X-Ray Computed; Treatment Failure; Treatment Outcome; Viral Load; Zidovudine | 2006 |
Structured treatment interruptions following immediate initiation of HAART in eight patients with acute HIV-1 seroconversion.
Topics: Acute Disease; Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Drug Therapy, Combination; Female; Follow-Up Studies; Histocompatibility Testing; HIV Seropositivity; HIV-1; Humans; Lamivudine; Lopinavir; Male; Pyrimidinones; Retrospective Studies; RNA, Viral; Stavudine; Treatment Outcome; Zidovudine | 2006 |
Weight and body shape changes in a treatment-naive population after 6 months of nevirapine-based generic highly active antiretroviral therapy in South India.
Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Body Composition; Body Weight; CD4 Lymphocyte Count; Cohort Studies; Female; HIV Infections; Humans; India; Lamivudine; Male; Nevirapine; Stavudine; Zidovudine | 2007 |
Comparison of the phosphorylation of 4'-ethynyl 2',3'-dihydro-3'-deoxythymidine with that of other anti-human immunodeficiency virus thymidine analogs.
Topics: Anti-HIV Agents; Humans; Nucleoside-Phosphate Kinase; Phosphorylation; Stavudine; Structure-Activity Relationship; Zidovudine | 2007 |
Nevirapine clearance from plasma in African adults stopping therapy: a pharmacokinetic substudy.
Topics: Adult; Cohort Studies; Drug Therapy, Combination; Female; HIV Infections; Humans; Lamivudine; Male; Middle Aged; Nevirapine; Reverse Transcriptase Inhibitors; Stavudine; Uganda; Zidovudine; Zimbabwe | 2007 |
Relationship of mitochondrial DNA depletion and respiratory chain activity in preadipocytes treated with nucleoside reverse transcriptase inhibitors.
Topics: 3T3-L1 Cells; Adipocytes; Adiponectin; Animals; Cell Differentiation; Cell Proliferation; Cell Shape; Dideoxynucleosides; DNA, Mitochondrial; Dose-Response Relationship, Drug; Electron Transport; HIV-Associated Lipodystrophy Syndrome; Mice; Phenotype; Reverse Transcriptase Inhibitors; Stavudine; Triglycerides; Zalcitabine; Zidovudine | 2007 |
NNRTI-selected mutations at codon 190 of human immunodeficiency virus type 1 reverse transcriptase decrease susceptibility to stavudine and zidovudine.
Topics: Amino Acid Substitution; Anti-HIV Agents; Drug Resistance, Viral; HIV Reverse Transcriptase; HIV-1; Inhibitory Concentration 50; Microbial Sensitivity Tests; Mutation; Nevirapine; Reverse Transcriptase Inhibitors; Stavudine; Zidovudine | 2007 |
Development of a highly efficient extraction technique and specific multiplex assay for measuring antiretroviral drug concentrations in breast milk.
Topics: Chromatography, High Pressure Liquid; Female; HIV Infections; Humans; Infectious Disease Transmission, Vertical; Lamivudine; Milk, Human; Nevirapine; Postpartum Period; Reproducibility of Results; Reverse Transcriptase Inhibitors; Sensitivity and Specificity; Spectrophotometry, Ultraviolet; Stavudine; Zidovudine | 2007 |
Pharmacokinetics of coadministered ritonavir-boosted elvitegravir and zidovudine, didanosine, stavudine, or abacavir.
Topics: Adolescent; Adult; Confidence Intervals; Cross-Over Studies; Didanosine; Dideoxynucleosides; Drug Interactions; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Quinolones; Stavudine; Zidovudine | 2007 |
Antiretroviral drug dosing errors in HIV-infected patients undergoing hemodialysis.
Topics: Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Dose-Response Relationship, Drug; Drug Administration Schedule; Follow-Up Studies; France; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Kaplan-Meier Estimate; Medication Errors; Prospective Studies; Renal Dialysis; Stavudine; Zidovudine | 2007 |
The excision mechanism in reverse transcriptase: pyrophosphate leaving and fingers opening are uncoupled events with the analogues AZT and d4T.
Topics: Diphosphates; Drug Resistance, Viral; HIV Reverse Transcriptase; Hydrogen; Models, Molecular; Molecular Conformation; Reverse Transcriptase Inhibitors; Stavudine; Zidovudine | 2007 |
Mitochondrial toxicity of indinavir, stavudine and zidovudine involves multiple cellular targets in white and brown adipocytes.
Topics: Adipocytes, Brown; Adipocytes, White; Adipogenesis; Animals; Anti-HIV Agents; Cell Line; DNA, Mitochondrial; HIV Protease Inhibitors; Indinavir; Mice; Mitochondria; Mitochondrial Proteins; Reverse Transcriptase Inhibitors; Stavudine; Transcription, Genetic; Zidovudine | 2007 |
Intracellular nucleoside triphosphate concentrations in HIV-infected patients on dual nucleoside reverse transcriptase inhibitor therapy.
Topics: Anti-HIV Agents; Cytidine Triphosphate; Dideoxynucleotides; Drug Therapy, Combination; Female; HIV Infections; Humans; Lamivudine; Leukocytes, Mononuclear; Male; Reverse Transcriptase Inhibitors; Stavudine; Thymine Nucleotides; Zidovudine | 2007 |
Liver enzymes elevation and immune reconstitution among treatment-naïve HIV-infected patients instituting antiretroviral therapy.
Topics: Adult; Alanine Transaminase; Alkynes; Anti-HIV Agents; Anti-Retroviral Agents; Aspartate Aminotransferases; Benzoxazines; CD4-Positive T-Lymphocytes; Cyclopropanes; Drug Therapy, Combination; Female; Hepatitis B; Hepatitis C; HIV Infections; Humans; Immune Reconstitution Inflammatory Syndrome; Lamivudine; Linear Models; Male; Middle Aged; Multivariate Analysis; Retrospective Studies; Risk Factors; Stavudine; Zidovudine | 2007 |
Decreasing CD4+ T-cell count during suppressed or low-level viraemia in patients with HIV infection.
Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Case-Control Studies; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; Female; HIV; HIV Infections; Humans; Male; RNA, Viral; Stavudine; Viral Load; Viremia; Zidovudine | 2007 |
Adaptation of antiretroviral therapy in human immunodeficiency virus infection with central nervous system involvement.
Topics: Adenine; Adult; AIDS Dementia Complex; Alkynes; Anti-HIV Agents; Anticonvulsants; Antiretroviral Therapy, Highly Active; Atazanavir Sulfate; Benzoxazines; Cerebrospinal Fluid; Cyclopropanes; Didanosine; HIV-1; Humans; Indinavir; Lamivudine; Male; Nelfinavir; Nevirapine; Oligopeptides; Organophosphonates; Pyridines; Ritonavir; Seizures; Stavudine; Tenofovir; Viral Load; Virus Replication; Zidovudine | 2008 |
Longitudinal effects of thymidine analogues on mtDNA, mtRNA and multidrug resistance (MDR-1) induction in cultured cells.
Topics: Anti-HIV Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; DNA, Mitochondrial; Dose-Response Relationship, Drug; Gene Expression Regulation; Humans; K562 Cells; RNA; RNA, Mitochondrial; Stavudine; Thymidine; Time Factors; Zidovudine | 2008 |
Haematological changes after switching from stavudine to zidovudine in HIV-infected children receiving highly active antiretroviral therapy.
Topics: Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Child; Cohort Studies; Drug Administration Schedule; Female; Hematologic Tests; HIV Infections; HIV-1; Humans; Male; Retrospective Studies; Stavudine; Treatment Outcome; Viral Load; Zidovudine | 2008 |
Zidovudine impairs adipogenic differentiation through inhibition of clonal expansion.
Topics: 3T3 Cells; Adipocytes; Adipogenesis; Animals; CCAAT-Enhancer-Binding Protein-alpha; CCAAT-Enhancer-Binding Protein-beta; Cell Differentiation; Cell Proliferation; Cells, Cultured; Gene Expression; Humans; Mice; PPAR gamma; Reverse Transcriptase Inhibitors; Reverse Transcriptase Polymerase Chain Reaction; Stavudine; Triglycerides; Zidovudine | 2008 |
[Evaluation of antiretroviral therapy in HIV-infected adults in the Department of Haematology, University Hospital of Brazzavllle, Congo].
Topics: Adolescent; Adult; Aged; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; CD4 Lymphocyte Count; Congo; Cyclopropanes; Didanosine; Drug Evaluation; Drug Therapy, Combination; Female; Hematology; HIV Infections; Hospital Departments; Hospitals, University; Humans; Lamivudine; Male; Middle Aged; Nevirapine; Retrospective Studies; Stavudine; Treatment Outcome; Viral Load; Zidovudine | 2008 |
The nucleoside reverse transcriptase inhibitors didanosine, lamivudine, stavudine and zidovudine show little effect on the virulence of Candida albicans in vitro.
Topics: Antifungal Agents; Biofilms; Candida albicans; Cell Adhesion; Cell Line; Didanosine; Humans; Lamivudine; Microbial Sensitivity Tests; Reverse Transcriptase Inhibitors; Stavudine; Virulence; Zidovudine | 2008 |
Evaluation of a systematic substitution of zidovudine for stavudine-based HAART in a program setting in rural Cambodia.
Topics: Anemia; Antiretroviral Therapy, Highly Active; Body Mass Index; Cambodia; CD4 Lymphocyte Count; HIV Infections; Humans; Patient Compliance; Retrospective Studies; Risk Factors; Rural Population; Stavudine; Zidovudine | 2008 |
Foscarnet salvage therapy efficacy is associated with the presence of thymidine-associated mutations (TAMs) in HIV-infected patients.
Topics: Adult; Anti-HIV Agents; Drug Resistance, Viral; Drug Therapy, Combination; Female; Foscarnet; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Male; Middle Aged; Mutation; Reverse Transcriptase Inhibitors; Salvage Therapy; Stavudine; Thymidine; Treatment Outcome; Zidovudine | 2008 |
Two-year outcomes of children on non-nucleoside reverse transcriptase inhibitor and protease inhibitor regimens in a South African pediatric antiretroviral program.
Topics: Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Child; Child, Preschool; Cohort Studies; Didanosine; Female; HIV Infections; HIV Protease Inhibitors; Humans; Infant; Lamivudine; Lopinavir; Male; Multivariate Analysis; Pyrimidinones; Retrospective Studies; Reverse Transcriptase Inhibitors; Ritonavir; South Africa; Stavudine; Treatment Outcome; Zidovudine | 2008 |
Weight evolution in HIV-1 infected women in Rwanda after stavudine substitution due to lipoatrophy: comparison of zidovudine with tenofovir/abacavir.
Topics: Adenine; Adult; Anti-HIV Agents; Body Weight; Dideoxynucleosides; Drug Therapy, Combination; Female; HIV-1; HIV-Associated Lipodystrophy Syndrome; Humans; Organophosphonates; Rwanda; Stavudine; Tenofovir; Treatment Outcome; Weight Loss; Zidovudine | 2009 |
Long-term exposure to AZT, but not d4T, increases endothelial cell oxidative stress and mitochondrial dysfunction.
Topics: Biomarkers; Cell Death; Cell Line, Tumor; Cells, Cultured; DNA, Mitochondrial; Endothelial Cells; Glutathione; Humans; Lactic Acid; Membrane Potential, Mitochondrial; Mitochondria; Mitochondria, Liver; Oxidative Stress; Phosphorylation; Reverse Transcriptase Inhibitors; Stavudine; Superoxides; Time Factors; Zidovudine | 2009 |
A prospective study evaluating clinical outcomes and costs of three NNRTI-based HAART regimens in Kerala, India.
Topics: Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; Female; HIV Infections; HIV-1; Hospitals, Teaching; Humans; India; Lamivudine; Male; Medication Adherence; Nevirapine; Prospective Studies; Stavudine; Treatment Outcome; Zidovudine | 2009 |
Apricitabine does not select additional drug resistance mutations in tissue culture in human immunodeficiency virus type 1 variants containing K65R, M184V, or M184V plus thymidine analogue mutations.
Topics: Anti-HIV Agents; Deoxycytidine; Drug Resistance, Viral; HIV Reverse Transcriptase; HIV-1; Mutation; Reverse Transcriptase Inhibitors; Stavudine; Zidovudine | 2009 |
Molecularly imprinted polymer for analysis of zidovudine and stavudine in human serum by liquid chromatography-mass spectrometry.
Topics: Anti-HIV Agents; Chromatography, High Pressure Liquid; Cross Reactions; Humans; Indicators and Reagents; Mass Spectrometry; Polymers; Solvents; Stavudine; Zidovudine | 2009 |
Safe substitution to zidovudine among HIV-infected patients initiated on stavudine-containing highly active antiretroviral therapy from a resource-limited setting.
Topics: Anemia; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Drug Administration Schedule; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; India; Poverty; Stavudine; Treatment Outcome; Zidovudine | 2009 |
Is it safe to switch from stavudine to zidovudine after developing symptomatic hyperlactatemia?
Topics: Acidosis, Lactic; Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Female; Humans; Middle Aged; Stavudine; Treatment Outcome; Uganda; Zidovudine | 2008 |
Retention of metabolites of 2',3'-didehydro-3'-deoxy-4'-ethynylthymidine, a novel anti-human immunodeficiency virus type 1 thymidine analog, in cells.
Topics: Anti-HIV Agents; Biological Transport; Cell Line; Cell Line, Tumor; Chromatography, High Pressure Liquid; Dipyridamole; Humans; Multidrug Resistance-Associated Proteins; Phosphodiesterase Inhibitors; Phosphorylation; Stavudine; Thymidine; Zidovudine | 2009 |
Gene expression and immunohistochemistry in adipose tissue of HIV type 1-infected patients with nucleoside analogue reverse-transcriptase inhibitor-associated lipoatrophy.
Topics: Adipocytes; Anti-HIV Agents; DNA Polymerase gamma; DNA-Directed DNA Polymerase; DNA, Mitochondrial; Female; Gene Expression Profiling; Gene Expression Regulation, Viral; Glucose; HIV-1; HIV-Associated Lipodystrophy Syndrome; Humans; Immunohistochemistry; Lipid Metabolism; Male; Middle Aged; Nucleic Acid Synthesis Inhibitors; Reverse Transcriptase Inhibitors; Stavudine; Subcutaneous Fat, Abdominal; Zidovudine | 2009 |
[Establishment of pharmacological evaluation system for non-nucleoside reverse-transcriptase inhibitors resistant HIV-1].
Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Cell Line; Cyclopropanes; Delavirdine; Drug Evaluation, Preclinical; Drug Resistance, Viral; Genetic Vectors; HIV Reverse Transcriptase; HIV-1; Humans; Membrane Glycoproteins; Nevirapine; Plasmids; Point Mutation; Reverse Transcriptase Inhibitors; Stavudine; Transfection; Viral Envelope Proteins; Virion; Virus Replication; Zidovudine | 2009 |
Rate of accumulation of thymidine analogue mutations in patients continuing to receive virologically failing regimens containing zidovudine or stavudine: implications for antiretroviral therapy programs in resource-limited settings.
Topics: Adolescent; Adult; Aged; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Drug Resistance, Viral; Female; HIV; HIV Infections; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Mutation, Missense; Stavudine; Young Adult; Zidovudine | 2009 |
Evaluation of HIV/AIDS clinical care quality: the case of a referral hospital in North West Ethiopia.
Topics: Adolescent; Anti-HIV Agents; Antibiotic Prophylaxis; Child; Child, Preschool; Cross-Sectional Studies; Ethiopia; Female; Guideline Adherence; HIV Infections; Humans; Infant; Male; Outcome and Process Assessment, Health Care; Patient Satisfaction; Quality of Health Care; Stavudine; Trimethoprim, Sulfamethoxazole Drug Combination; Young Adult; Zidovudine | 2009 |
Thymidine analogue resistance suppression by V75I of HIV-1 reverse transcriptase: effects of substituting valine 75 on stavudine excision and discrimination.
Topics: Acyclovir; Adenosine Triphosphate; Anti-HIV Agents; DNA Mutational Analysis; DNA Primers; Drug Resistance, Multiple; Drug Resistance, Viral; HIV Reverse Transcriptase; HIV-1; Humans; Kinetics; Stavudine; Thymidine; Valine; Zidovudine | 2009 |
Combined effect of C-reactive protein and stavudine on adipogenesis.
Topics: 3T3 Cells; Adipogenesis; Animals; Anti-HIV Agents; Biomarkers; C-Reactive Protein; Drug Therapy, Combination; Mice; Stavudine; Zidovudine | 2009 |
Synthesis and antiviral activity of boranophosphonate isosteres of AZT and d4T monophosphates.
Topics: Animals; Antiviral Agents; Cell Line; Drug Stability; Half-Life; Humans; Organophosphonates; Stavudine; Viruses; Zidovudine | 2010 |
Cost-effectiveness of tenofovir as first-line antiretroviral therapy in India.
Topics: Adenine; Adult; Antifungal Agents; Antiretroviral Therapy, Highly Active; Cost-Benefit Analysis; Female; HIV Infections; Humans; India; Male; Organophosphonates; Stavudine; Survival Analysis; Tenofovir; Treatment Outcome; Zidovudine | 2010 |
Analysis of RT sequences of subtype C HIV-type 1 isolates from indian patients at failure of a first-line treatment according to clinical and/or immunological WHO guidelines.
Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Drug Resistance, Multiple, Viral; Drug Therapy, Combination; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; India; Lamivudine; Molecular Sequence Data; Nevirapine; Polymorphism, Single Nucleotide; Stavudine; Treatment Failure; Zidovudine | 2010 |
Positive and negative drug selection pressures on the N348I connection domain mutation: new insights from in vivo data.
Topics: Adenine; Alkynes; Anti-HIV Agents; Benzoxazines; Case-Control Studies; Cyclopropanes; Databases, Genetic; Drug Administration Schedule; Drug Resistance, Viral; Drug Therapy, Combination; HIV Reverse Transcriptase; HIV-1; Humans; Logistic Models; Mutation; Nevirapine; Organophosphonates; Reverse Transcriptase Inhibitors; Stavudine; Tenofovir; Zidovudine | 2010 |
[Durability and tolerability of long-term nevirapine-based HAART].
Topics: Adult; Aged; Antiretroviral Therapy, Highly Active; Comorbidity; Dideoxynucleosides; Female; Hepatitis, Viral, Human; HIV Infections; HIV Protease Inhibitors; Humans; Lamivudine; Lipids; Liver Function Tests; Male; Middle Aged; Nevirapine; Retrospective Studies; Stavudine; Viral Load; Young Adult; Zidovudine | 2010 |
Proteomic analysis identifies prohibitin down-regulation as a crucial event in the mitochondrial damage observed in HIV-infected patients.
Topics: Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Down-Regulation; Electrophoresis, Gel, Two-Dimensional; HIV Infections; HIV-1; Humans; Mitochondria; Prohibitins; Proteomics; Repressor Proteins; Reverse Transcriptase Inhibitors; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Stavudine; Zidovudine | 2010 |
Possible mitochondrial dysfunction and its association with antiretroviral therapy use in children perinatally infected with HIV.
Topics: Adolescent; Anti-HIV Agents; Child; Child, Preschool; Cohort Studies; Female; HIV Infections; Humans; Infant, Newborn; Male; Mitochondrial Diseases; Pregnancy; Prenatal Exposure Delayed Effects; Prospective Studies; Regression Analysis; Stavudine; United States; Zidovudine | 2010 |
Simultaneous determination of stavudine and lamivudine in human plasma by high performance liquid chromatography and its application to a bioavailability study.
Topics: Anti-HIV Agents; Biological Availability; Chromatography, High Pressure Liquid; Drug Stability; Humans; Lamivudine; Reference Standards; Stavudine; Zidovudine | 2010 |
Pyrimidine deoxynucleoside and nucleoside reverse transcriptase inhibitor metabolism in the perfused heart and isolated mitochondria.
Topics: Animals; Anti-HIV Agents; Deoxycytidine; Male; Mitochondria, Heart; Myocardium; Nucleosides; Perfusion; Phosphorylation; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Inhibitors; Stavudine; Thymidine; Zalcitabine; Zidovudine | 2010 |
Assessment of the prevalence of distal symmetrical polyneuropathy and its risk factors among HAART-treated and untreated HIV infected individuals.
Topics: Adolescent; Adult; Age Distribution; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Cross-Sectional Studies; Ethiopia; Female; HIV Infections; HIV-1; Hospitals, Teaching; Humans; Male; Middle Aged; Neurologic Examination; Polyneuropathies; Prevalence; Risk Factors; Socioeconomic Factors; Stavudine; Young Adult; Zidovudine | 2010 |
Progressive mitochondrial compromise in brains and livers of primates exposed in utero to nucleoside reverse transcriptase inhibitors (NRTIs).
Topics: Animals; Animals, Newborn; Cerebral Cortex; Didanosine; Disease Models, Animal; DNA, Mitochondrial; Drug Therapy, Combination; Erythrocebus patas; Female; Lamivudine; Maternal Exposure; Mitochondria, Liver; Oxidative Phosphorylation; Pregnancy; Reverse Transcriptase Inhibitors; Stavudine; Zidovudine | 2010 |
Genotypic and phenotypic cross-drug resistance of harboring drug-resistant HIV type 1 subtype B' strains from former blood donors in central Chinese provinces.
Topics: Adult; Anti-HIV Agents; Blood Donors; China; Didanosine; Drug Resistance, Multiple, Viral; Female; Genotype; HIV Infections; HIV-1; Humans; Lamivudine; Male; Middle Aged; Mutation; Phenotype; pol Gene Products, Human Immunodeficiency Virus; RNA, Viral; Sequence Analysis, RNA; Stavudine; Zidovudine | 2010 |
Mechanisms involved in the selection of HIV-1 reverse transcriptase thumb subdomain polymorphisms associated with nucleoside analogue therapy failure.
Topics: Cell Line; Cells, Cultured; Dideoxynucleosides; Drug Resistance, Viral; HIV Infections; HIV Reverse Transcriptase; Humans; Polymorphism, Genetic; Reverse Transcriptase Inhibitors; Stavudine; Virus Replication; Zidovudine | 2010 |
Stavudine toxicity in women is the main reason for treatment change in a 3-year prospective cohort of adult patients started on first-line antiretroviral treatment in Uganda.
Topics: Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Cyclopropanes; Female; HIV Infections; Humans; Kaplan-Meier Estimate; Lamivudine; Male; Multivariate Analysis; Nevirapine; Prospective Studies; Risk Factors; Sex Factors; Stavudine; Uganda; Zidovudine | 2011 |
Evaluating patients for second-line antiretroviral therapy in India: the role of targeted viral load testing.
Topics: Adult; Alkynes; Anti-HIV Agents; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; Female; HIV; HIV Infections; Humans; India; Lamivudine; Male; Middle Aged; Nevirapine; RNA, Viral; Stavudine; Treatment Failure; Viral Load; Zidovudine | 2010 |
Reduced dose of stavudine and lipoatrophy in HIV-infected patients in Cameroon.
Topics: Adult; Anti-HIV Agents; Cameroon; CD4 Lymphocyte Count; Cross-Sectional Studies; Female; HIV; HIV Infections; Humans; Lamivudine; Lipodystrophy; Male; Middle Aged; Nevirapine; Stavudine; Zidovudine | 2010 |
Determinants of individual variation in intracellular accumulation of anti-HIV nucleoside analog metabolites.
Topics: Anti-HIV Agents; CD4-Positive T-Lymphocytes; Cross-Sectional Studies; Deoxycytidine Kinase; Female; HIV Seronegativity; Humans; Lamivudine; Leukocytes, Mononuclear; Lymphocyte Activation; Male; Nucleosides; Polyphosphates; Sex Factors; Stavudine; Thymidine Kinase; Treatment Outcome; Zidovudine | 2011 |
Synthesis and in vitro human skin penetration of oligo- and polymeric ethylene glycol carbonates of zidovudine and stavudine.
Topics: Administration, Cutaneous; Adult; Anti-HIV Agents; Carbonates; Chromatography, High Pressure Liquid; Ethylene Glycol; Female; Humans; In Vitro Techniques; Indicators and Reagents; Kinetics; Lipids; Magnetic Resonance Spectroscopy; Mass Spectrometry; Skin Absorption; Solubility; Stavudine; Water; Zidovudine | 2010 |
Diastereoselective synthesis of cyclosaligenyl-nucleosyl-phosphotriesters.
Topics: Anti-HIV Agents; Dideoxynucleotides; Humans; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Nucleotides; Organophosphates; Stavudine; Stereoisomerism; Structure-Activity Relationship; Zidovudine | 2011 |
Thymidine analogue excision and discrimination modulated by mutational complexes including single amino acid deletions of Asp-67 or Thr-69 in HIV-1 reverse transcriptase.
Topics: DNA, Viral; HIV Reverse Transcriptase; HIV-1; Humans; Kinetics; Mutation; Stavudine; Zidovudine | 2011 |
Identification of amino acid phosphorodiamidates of antiviral nucleosides using electrospray ionization tandem mass spectrometry.
Topics: Amino Acids; Anti-HIV Agents; Phosphorus Compounds; Spectrometry, Mass, Electrospray Ionization; Stavudine; Tandem Mass Spectrometry; Zidovudine | 2011 |
Cost and cost-effectiveness of switching from d4T or AZT to a TDF-based first-line regimen in a resource-limited setting in rural Lesotho.
Topics: Adenine; Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Cost-Benefit Analysis; Developing Countries; Female; Health Care Costs; HIV Infections; Humans; Lesotho; Male; Middle Aged; Organophosphonates; Pregnancy; Rural Population; Stavudine; Tenofovir; Zidovudine | 2011 |
[Association between the change regularity of peripheral blood mononuclear cell mitochondrial deoxyribonucleic acid content and human immunodeficiency virus-related lipodystrophy].
Topics: Adult; Antiretroviral Therapy, Highly Active; Case-Control Studies; DNA, Mitochondrial; Female; HIV-Associated Lipodystrophy Syndrome; Humans; Leukocytes, Mononuclear; Male; Middle Aged; Stavudine; Young Adult; Zidovudine | 2011 |
Evaluation of incidence of zidovudine induced anemia in Indian human immunodeficiency virus positive patients in comparison with stavudine based highly active antiretroviral therapy.
Topics: Adult; Anemia; Anti-Retroviral Agents; Antiretroviral Therapy, Highly Active; Case-Control Studies; Female; Hemoglobins; HIV Infections; Humans; Incidence; India; Male; Multivariate Analysis; Prospective Studies; Risk Factors; Severity of Illness Index; Stavudine; Zidovudine | 2011 |
Recovery from lipodystrophy in HIV-infected children after substitution of stavudine with zidovudine in a non-nucleoside reverse transcriptase inhibitor-based antiretroviral therapy.
Topics: Adolescent; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Child; Child, Preschool; Female; HIV Infections; Humans; Lipodystrophy; Male; Retrospective Studies; Severity of Illness Index; Stavudine; Thailand; Treatment Outcome; Zidovudine | 2012 |
Common inherited mitochondrial DNA mutations and nucleoside reverse transcriptase inhibitor-induced severe hyperlactataemia in HIV-infected adults: an exploratory study.
Topics: Acidosis, Lactic; Adult; Anti-HIV Agents; Black People; Case-Control Studies; Didanosine; DNA, Mitochondrial; Female; HIV Infections; Humans; Leukocytes, Mononuclear; Male; Middle Aged; Mitochondria; Mutation; Polymorphism, Single Nucleotide; Reverse Transcriptase Inhibitors; Sequence Deletion; Stavudine; White People; Zidovudine | 2012 |
Adverse drug reactions to antiretroviral therapy (ARVs): incidence, type and risk factors in Nigeria.
Topics: Adenine; Adolescent; Adult; Alkynes; Anti-Retroviral Agents; Benzoxazines; Cohort Studies; Cyclopropanes; Drug-Related Side Effects and Adverse Reactions; Exanthema; Female; HIV Infections; Humans; Incidence; Lamivudine; Male; Middle Aged; Nevirapine; Nigeria; Organophosphonates; Pain; Retrospective Studies; Risk Factors; Stavudine; Tenofovir; Zidovudine | 2012 |
Azidothymidine and other chain terminators are mutagenic for template-switch-generated genetic mutations.
Topics: Anti-HIV Agents; Base Sequence; Didanosine; DNA, Bacterial; Escherichia coli; Models, Genetic; Mutagens; Mutation; Stavudine; Templates, Genetic; Zidovudine | 2012 |
Increased incidence of symptomatic peripheral neuropathy among adults receiving stavudine- versus zidovudine-based antiretroviral regimens in Kenya.
Topics: Adult; Anti-HIV Agents; Female; HIV Infections; Humans; Incidence; Kenya; Male; Peripheral Nervous System Diseases; Probability; Retrospective Studies; Stavudine; Treatment Outcome; Zidovudine | 2012 |
Metabolism of deoxypyrimidines and deoxypyrimidine antiviral analogs in isolated brain mitochondria.
Topics: Animals; Brain; Chromatography, High Pressure Liquid; Deoxycytidine; Deoxyuridine; Dose-Response Relationship, Drug; Kinetics; Male; Mitochondria; Nucleotidases; Phosphorylation; Pyrimidine Nucleosides; Rats; Rats, Sprague-Dawley; Stavudine; Thymidine; Time Factors; Tritium; Zidovudine | 2012 |
K65R in subtype C HIV-1 isolates from patients failing on a first-line regimen including d4T or AZT: comparison of Sanger and UDP sequencing data.
Topics: HIV Infections; HIV-1; Humans; Mutation; Reverse Transcriptase Inhibitors; Stavudine; Zidovudine | 2012 |
A pyrophosphatase activity associated with purified HIV-1 particles.
Topics: Adenosine Triphosphate; Anti-HIV Agents; Dideoxynucleotides; Diphosphates; DNA, Viral; Drug Resistance, Viral; HIV Reverse Transcriptase; HIV-1; Kinetics; Mutation; Pyrophosphatases; Stavudine; Substrate Specificity; Thymine Nucleotides; Virion; Zidovudine | 2012 |
Monitoring of HAART regime antiretrovirals in serum of acquired immunodeficiency syndrome patients by micellar liquid chromatography.
Topics: Acquired Immunodeficiency Syndrome; Adenine; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Chromatography, Liquid; Cyclopropanes; Drug Monitoring; Humans; Lamivudine; Organophosphonates; Stavudine; Tenofovir; Zidovudine | 2012 |
Effects of daily intake of zidovudine-stavudine on rat pregnancy outcome: biological essay.
Topics: Animals; Anti-HIV Agents; Biological Assay; Disease Models, Animal; Drug Combinations; Female; HIV Infections; Pregnancy; Pregnancy Complications, Infectious; Pregnancy Outcome; Rats; Stavudine; Weight Gain; Zidovudine | 2012 |
Autophagy inhibition due to thymidine analogues as novel mechanism leading to hepatocyte dysfunction and lipid accumulation.
Topics: Anti-HIV Agents; Autophagy; Blotting, Western; Cells, Cultured; DNA, Mitochondrial; Fatty Liver; Female; Flow Cytometry; Hep G2 Cells; HIV Infections; Humans; Lipid Metabolism; Male; Microscopy, Electron; Mitochondria, Liver; Non-alcoholic Fatty Liver Disease; Stavudine; Thymidine; Zidovudine | 2012 |
Resistance-associated mutations after initial antiretroviral treatment failure in a large cohort of patients infected with HIV-1 subtype CRF01_AE.
Topics: Adult; Aged; Anti-HIV Agents; Cohort Studies; Drug Resistance, Multiple, Viral; Female; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Male; Middle Aged; Mutation; Reverse Transcriptase Inhibitors; RNA, Viral; Stavudine; Thailand; Thymidine; Treatment Failure; Zidovudine | 2012 |
Thymidine analogues suppress autophagy and adipogenesis in cultured adipocytes.
Topics: Adipocytes; Adipogenesis; Androstadienes; Animals; Autophagy; Autophagy-Related Protein 5; Cell Differentiation; Cell Line; Cell Proliferation; Cell Survival; Chromones; Flow Cytometry; Humans; Lamivudine; Mice; Microscopy, Fluorescence; Microtubule-Associated Proteins; Mitochondria; Morpholines; Nocodazole; Phagosomes; Reverse Transcriptase Inhibitors; RNA, Small Interfering; Stavudine; Wortmannin; Zidovudine | 2013 |
In vitro and ex vivo inhibition of human telomerase by anti-HIV nucleoside reverse transcriptase inhibitors (NRTIs) but not by non-NRTIs.
Topics: Adenine; Alkynes; Anti-HIV Agents; Benzoxazines; Cell Line; Cyclopropanes; Didanosine; Dideoxynucleosides; DNA Primers; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Nevirapine; Organophosphonates; Reverse Transcriptase Inhibitors; Stavudine; Telomerase; Tenofovir; Zidovudine | 2012 |
Impact of hepatitis C virus on HIV response to antiretroviral therapy in Nigeria.
Topics: Adult; Alanine Transaminase; Alkynes; Anti-Retroviral Agents; Benzoxazines; Chemical and Drug Induced Liver Injury; Coinfection; Cyclopropanes; Deoxycytidine; Drug Combinations; Drug Therapy, Combination; Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination; Female; Hepacivirus; Hepatitis C, Chronic; HIV Infections; Humans; Lamivudine; Logistic Models; Male; Nevirapine; Nigeria; Organophosphorus Compounds; RNA, Viral; Stavudine; Zidovudine | 2013 |
The pattern of attrition from an antiretroviral treatment program in Nigeria.
Topics: Adolescent; Adult; Anti-Retroviral Agents; Child; Child, Preschool; Cohort Studies; Female; HIV Infections; Hospitals; Humans; Male; Medication Adherence; Middle Aged; Nigeria; Patient Compliance; Proportional Hazards Models; Retrospective Studies; Risk Factors; Stavudine; Time Factors; Treatment Outcome; Zidovudine | 2012 |
[The influence of long-term nucleotide reverse transcriptase inhibitors on lipids metabolism in HIV/AIDS patients].
Topics: Acquired Immunodeficiency Syndrome; Adult; Antiretroviral Therapy, Highly Active; Case-Control Studies; Cross-Sectional Studies; Female; HIV Infections; Humans; Lipid Metabolism; Lipodystrophy; Male; Middle Aged; Reverse Transcriptase Inhibitors; Stavudine; Zidovudine | 2012 |
Prevalence of highly active antiretroviral therapy associated metabolic abnormalities and lipodystrophy in HIV infected patients.
Topics: Adult; Aged, 80 and over; Anti-Retroviral Agents; Antiretroviral Therapy, Highly Active; Cross-Sectional Studies; Ethiopia; Female; HIV Infections; HIV-Associated Lipodystrophy Syndrome; Humans; Hypercholesterolemia; Hyperglycemia; Hypertriglyceridemia; Interviews as Topic; Male; Metabolic Diseases; Middle Aged; Prevalence; Risk Factors; Stavudine; Surveys and Questionnaires; Zidovudine | 2012 |
Vitamin D attenuates nucleoside reverse transcriptase inhibitor induced human skeletal muscle mitochondria DNA depletion.
Topics: Anti-HIV Agents; Calcitriol; Didanosine; DNA, Mitochondrial; Drug Therapy, Combination; Female; HIV Reverse Transcriptase; Humans; Infant; Lamivudine; Mitochondria, Muscle; Muscle Fibers, Skeletal; Muscle, Skeletal; Myoblasts; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Inhibitors; Stavudine; Vitamins; Zidovudine | 2013 |
Risk factors of treatment-limiting anemia after substitution of zidovudine for stavudine in HIV-infected adult patients on antiretroviral treatment.
Topics: Adult; Anemia; Anti-HIV Agents; Female; HIV Infections; Humans; Male; Retrospective Studies; Risk Factors; Stavudine; Zidovudine | 2013 |
Cardiometabolic risk factors among HIV patients on antiretroviral therapy.
Topics: Adenine; Adolescent; Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Cardiovascular Diseases; Cholesterol, HDL; Cholesterol, LDL; Cyclopropanes; Female; HIV; HIV Infections; Humans; Insulin Resistance; Lamivudine; Male; Middle Aged; Nevirapine; Organophosphonates; Risk Factors; Stavudine; Tenofovir; Triglycerides; Zambia; Zidovudine | 2013 |
The NRTIs lamivudine, stavudine and zidovudine have reduced HIV-1 inhibitory activity in astrocytes.
Topics: Anti-HIV Agents; Astrocytes; Cell Line; HIV-1; Humans; Reverse Transcriptase Inhibitors; Stavudine; Zidovudine | 2013 |
Nucleoside reverse transcriptase inhibitor resistance mutations associated with first-line stavudine-containing antiretroviral therapy: programmatic implications for countries phasing out stavudine.
Topics: Adenine; Alkynes; Anti-Retroviral Agents; Benzoxazines; Cyclopropanes; Databases, Factual; Drug Resistance, Viral; Drug Therapy, Combination; Genotype; HIV Infections; HIV-1; Humans; Mutation, Missense; Nevirapine; Organophosphonates; Reverse Transcriptase Inhibitors; RNA, Viral; Stavudine; Tenofovir; Zidovudine | 2013 |
Comparison of tenofovir, zidovudine, or stavudine as part of first-line antiretroviral therapy in a resource-limited-setting: a cohort study.
Topics: Adenine; Adolescent; Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Cohort Studies; Female; Health Resources; HIV; HIV Infections; Humans; Male; Middle Aged; Organophosphonates; Residence Characteristics; RNA, Viral; Stavudine; Tenofovir; Young Adult; Zidovudine | 2013 |
Baseline CD4 cell counts and outcomes among adult treatment naive HIV patients after taking fixed dose combination GPO-VIR-S and GPO-VIR-Z in Thailand.
Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Female; Hematologic Tests; HIV Infections; Humans; Immune Reconstitution Inflammatory Syndrome; Kaplan-Meier Estimate; Lamivudine; Male; Middle Aged; Nevirapine; Retrospective Studies; Stavudine; Thailand; Treatment Outcome; Viral Load; Zidovudine | 2013 |
Adherence to antiretroviral therapy among HIV infected children measured by caretaker report, medication return, and drug level in Dar Es Salaam, Tanzania.
Topics: Adolescent; Adult; Aged; Anti-HIV Agents; Caregivers; CD4 Lymphocyte Count; Child; Child, Preschool; Cross-Sectional Studies; Drug Administration Schedule; Drug Combinations; Female; HIV Infections; Humans; Lamivudine; Logistic Models; Male; Medication Adherence; Middle Aged; Nevirapine; Odds Ratio; Stavudine; Surveys and Questionnaires; Tanzania; Young Adult; Zidovudine | 2013 |
HIV-1 drug-resistance surveillance among treatment-experienced and -naïve patients after the implementation of antiretroviral therapy in Ghana.
Topics: Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Child; Child, Preschool; Cyclopropanes; Drug Resistance, Viral; Epidemiological Monitoring; Female; Ghana; HIV Infections; HIV Protease; HIV-1; Humans; Infant; Lamivudine; Male; Middle Aged; Molecular Epidemiology; Molecular Typing; Mutation, Missense; Nevirapine; Prevalence; Sequence Analysis, DNA; Stavudine; Zidovudine | 2013 |
High-levels of acquired drug resistance in adult patients failing first-line antiretroviral therapy in a rural HIV treatment programme in KwaZulu-Natal, South Africa.
Topics: Adolescent; Adult; Alkynes; Analysis of Variance; Anti-HIV Agents; Benzoxazines; Cross-Sectional Studies; Cyclopropanes; Drug Resistance, Viral; Drug Therapy, Combination; Female; Genotype; HIV Infections; HIV-1; Humans; Lamivudine; Male; Middle Aged; Mutation; Nevirapine; Outcome Assessment, Health Care; Prevalence; South Africa; Stavudine; Young Adult; Zidovudine | 2013 |
A novel synthesis of antiviral nucleoside phosphoramidate and thiophosphoramidate prodrugs via nucleoside H-phosphonamidates.
Topics: Amides; Antiviral Agents; Magnetic Resonance Spectroscopy; Nucleosides; Organothiophosphorus Compounds; Phosphoric Acids; Prodrugs; Pyrimidine Nucleosides; Stavudine; Zidovudine | 2013 |
Tenofovir or zidovudine in second-line antiretroviral therapy after stavudine failure in southern Africa.
Topics: Adenine; Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Female; HIV Infections; Humans; Male; Middle Aged; Organophosphonates; Retreatment; South Africa; Stavudine; Tenofovir; Treatment Failure; Treatment Outcome; Viral Load; Zidovudine | 2014 |
Trends in clinical characteristics of HIV-infected patients initiating antiretroviral therapy in Shanghai from 2006 to 2011.
Topics: Adolescent; Adult; Anti-Retroviral Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; China; Cross-Sectional Studies; Female; HIV Infections; Humans; Immune Tolerance; Lamivudine; Male; Middle Aged; Nevirapine; Retrospective Studies; Stavudine; Viral Load; Zidovudine | 2014 |
An antiretroviral regimen containing 6 months of stavudine followed by long-term zidovudine for first-line HIV therapy is optimal in resource-limited settings: a prospective, multicenter study in China.
Topics: Adult; Anti-HIV Agents; Female; HIV Infections; Humans; Male; Middle Aged; Prospective Studies; Stavudine; Zidovudine | 2014 |
Preliminary study of quinine pharmacokinetics in pregnant women with malaria-HIV co-infection.
Topics: Adult; Anti-HIV Agents; Antimalarials; Antiretroviral Therapy, Highly Active; Coinfection; Drug Interactions; Female; HIV Infections; Humans; Lamivudine; Malaria, Falciparum; Nevirapine; Parasite Load; Pregnancy; Pregnancy Complications, Infectious; Prospective Studies; Quinidine; Quinine; Stavudine; Treatment Outcome; Young Adult; Zidovudine | 2014 |
Long-term exposure of mice to nucleoside analogues disrupts mitochondrial DNA maintenance in cortical neurons.
Topics: Animals; Antimetabolites; Cells, Cultured; Cerebral Cortex; Didanosine; DNA, Mitochondrial; Lamivudine; Liver; Mice; Mitochondria; Muscle, Skeletal; Neurons; Stavudine; Zidovudine | 2014 |
Clinical profile and response to first-line ARV in HIV patients from Eastern UP and Bihar: a retrospective study.
Topics: Adolescent; Adult; Aged; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Female; HIV Infections; Humans; India; Lamivudine; Male; Middle Aged; Nevirapine; Retrospective Studies; Reverse Transcriptase Inhibitors; Stavudine; Treatment Outcome; Young Adult; Zidovudine | 2013 |
Hepatitis B and C co-infection among HIV-infected adults while on antiretroviral treatment: long-term survival, CD4 cell count recovery and antiretroviral toxicity in Cambodia.
Topics: Adult; Alkynes; Anti-Retroviral Agents; Benzoxazines; Cambodia; CD4 Lymphocyte Count; Coinfection; Cyclopropanes; Female; Hepatitis B; Hepatitis C; HIV Infections; Humans; Kaplan-Meier Estimate; Lamivudine; Liver; Logistic Models; Male; Middle Aged; Nevirapine; Proportional Hazards Models; Retrospective Studies; Stavudine; Treatment Outcome; Zidovudine | 2014 |
Genome-wide association study of peripheral neuropathy with D-drug-containing regimens in AIDS Clinical Trials Group protocol 384.
Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Case-Control Studies; Drug Combinations; Drug Therapy, Combination; Genome-Wide Association Study; Genotype; Humans; Lamivudine; Multicenter Studies as Topic; Peripheral Nervous System Diseases; Polymorphism, Genetic; Principal Component Analysis; Randomized Controlled Trials as Topic; Retrospective Studies; Stavudine; Treatment Outcome; Zidovudine | 2014 |
Challenges of antiretroviral treatment monitoring in rural and remote-access regions in Africa.
Topics: Acquired Immunodeficiency Syndrome; Adult; Africa; Alkynes; Anti-HIV Agents; Benzoxazines; Cross-Sectional Studies; Cyclopropanes; Drug Monitoring; Drug Resistance, Viral; Female; HIV-1; Hospitals, Rural; Humans; Lamivudine; Male; Middle Aged; Nevirapine; Rural Health Services; Rural Population; Stavudine; Treatment Outcome; Zidovudine | 2014 |
Presence of HIV drug resistance in antiretroviral therapy-naive and -experienced patients from Papua New Guinea.
Topics: Adolescent; Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Cyclopropanes; Dried Blood Spot Testing; Drug Resistance, Viral; Female; HIV Infections; HIV Seropositivity; HIV-1; Humans; Lamivudine; Male; Middle Aged; Nevirapine; Papua New Guinea; Reverse Transcriptase Inhibitors; Stavudine; Treatment Failure; Viral Load; Young Adult; Zidovudine | 2014 |
MicroRNA-150 is a potential biomarker of HIV/AIDS disease progression and therapy.
Topics: Acquired Immunodeficiency Syndrome; Adult; Alkynes; Antiretroviral Therapy, Highly Active; Benzoxazines; Biomarkers; CD4 Lymphocyte Count; Cyclopropanes; Disease Progression; Drug Resistance, Viral; Female; Gene Expression Regulation; HIV; Humans; Lamivudine; Leukocytes, Mononuclear; Male; MicroRNAs; Nevirapine; Stavudine; Treatment Outcome; Viral Load; Zidovudine | 2014 |
SAMHD1 has differential impact on the efficacies of HIV nucleoside reverse transcriptase inhibitors.
Topics: Adenine; Cell Line; Dideoxynucleotides; Gene Expression; Genes, Reporter; HIV Reverse Transcriptase; HIV-1; Host-Pathogen Interactions; Humans; Lamivudine; Luciferases; Monocytes; Monomeric GTP-Binding Proteins; Organophosphonates; Reverse Transcriptase Inhibitors; RNA, Small Interfering; SAM Domain and HD Domain-Containing Protein 1; Stavudine; Tenofovir; Virus Replication; Zidovudine | 2014 |
Impact of Y181C and/or H221Y mutation patterns of HIV-1 reverse transcriptase on phenotypic resistance to available non-nucleoside and nucleoside inhibitors in China.
Topics: Alkynes; Benzoxazines; China; Cyclopropanes; Drug Resistance, Multiple, Viral; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Mutation; Nevirapine; Phenotype; Reverse Transcriptase Inhibitors; Stavudine; Zidovudine | 2014 |
SAMHD1 specifically affects the antiviral potency of thymidine analog HIV reverse transcriptase inhibitors.
Topics: CD4-Positive T-Lymphocytes; Gene Expression; HIV Reverse Transcriptase; HIV-2; Host-Pathogen Interactions; Humans; Jurkat Cells; Macrophages; Monomeric GTP-Binding Proteins; Primary Cell Culture; Reverse Transcriptase Inhibitors; SAM Domain and HD Domain-Containing Protein 1; Stavudine; Thymidine; Viral Regulatory and Accessory Proteins; Virus Replication; Zidovudine | 2014 |
Evaluating the utility of early laboratory monitoring of antiretroviral-induced haematological and hepatic toxicity in HIV-infected persons in Cameroon.
Topics: Adult; Anemia; Anti-HIV Agents; Cameroon; Chemical and Drug Induced Liver Injury; Early Diagnosis; Female; HIV Infections; Humans; Male; Middle Aged; Prevalence; Retrospective Studies; Stavudine; Zidovudine | 2014 |
[To evaluate the changes in body composition in male human immunodeficiency virus-related lipodystrophy after different treatment regimens by dual-energy X-ray absorptiometry].
Topics: Absorptiometry, Photon; Adenine; Anti-HIV Agents; Antiviral Agents; Body Composition; HIV Infections; HIV-Associated Lipodystrophy Syndrome; Humans; Male; Organophosphonates; Stavudine; Tenofovir; Zidovudine | 2014 |
Commentary: The place of tenofovir disoproxil fumarate in pediatric antiretroviral therapy.
Topics: Adenine; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Drug Utilization; Drug-Related Side Effects and Adverse Reactions; Female; HIV Infections; HIV-1; Humans; Male; Organophosphonates; Stavudine; Zidovudine | 2015 |
Mitochondrial and Oxidative Stress Response in HepG2 Cells Following Acute and Prolonged Exposure to Antiretroviral Drugs.
Topics: Anti-Retroviral Agents; DNA, Mitochondrial; Gene Expression Regulation; Hep G2 Cells; Humans; Membrane Potential, Mitochondrial; Mitochondria; Oxidative Stress; Reactive Oxygen Species; Stavudine; Tenofovir; Zidovudine | 2015 |
[Analysis on HIV suppression effect after initiating antiretroviral treatment and related factors among AIDS patients in Henan province during 2008 and 2013].
Topics: Acquired Immunodeficiency Syndrome; Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Female; Health Facilities; HIV Infections; Humans; Lamivudine; Male; Nevirapine; Stavudine; Time-to-Treatment; Treatment Outcome; Zidovudine | 2015 |
Caenorhabditis elegans as a Model System for Studying Drug Induced Mitochondrial Toxicity.
Topics: Animals; Anti-HIV Agents; Caenorhabditis elegans; Didanosine; Dideoxynucleosides; DNA-Directed DNA Polymerase; DNA, Mitochondrial; Drug Evaluation; Humans; Mitochondria; Mitochondrial Proteins; Models, Biological; Oxygen Consumption; Reverse Transcriptase Inhibitors; Stavudine; Ubiquinone; Zalcitabine; Zidovudine | 2015 |
Mitochondrial DNA D-loop AG/TC transition mutation in cortical neurons of mice after long-term exposure to nucleoside analogues.
Topics: Animals; Cerebral Cortex; Didanosine; DNA, Mitochondrial; Lamivudine; Laser Capture Microdissection; Mice; Mice, Inbred BALB C; Mutation; Neurons; Polymerase Chain Reaction; Reverse Transcriptase Inhibitors; Stavudine; Zidovudine | 2015 |
Longitudinal Analysis of Adherence to First-Line Antiretroviral Therapy: Evidence of Treatment Sustainability from an Indian HIV Cohort.
Topics: Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; Drug Administration Schedule; Female; HIV Infections; Humans; India; Lamivudine; Longitudinal Studies; Male; Medication Adherence; Middle Aged; Nevirapine; Reverse Transcriptase Inhibitors; Stavudine; Zidovudine | 2016 |
Plasma Mitochondrial DNA Levels as a Biomarker of Lipodystrophy Among HIV-infected Patients Treated with Highly Active Antiretroviral Therapy (HAART).
Topics: Adult; Alkynes; Antiretroviral Therapy, Highly Active; Benzoxazines; Biomarkers; Case-Control Studies; Cyclopropanes; DNA, Mitochondrial; Drug Combinations; Female; HIV; HIV Infections; Humans; Lamivudine; Lipodystrophy; Lopinavir; Male; Middle Aged; Mitochondria; Nelfinavir; Predictive Value of Tests; Ritonavir; ROC Curve; Stavudine; Zidovudine | 2015 |
Naringin Reverses Hepatocyte Apoptosis and Oxidative Stress Associated with HIV-1 Nucleotide Reverse Transcriptase Inhibitors-Induced Metabolic Complications.
Topics: Animals; Anti-HIV Agents; Apoptosis; Flavanones; Hepatocytes; Male; Oxidative Stress; Rats; Rats, Wistar; Reverse Transcriptase Inhibitors; Stavudine; Zidovudine | 2015 |
Improved pregnancy outcomes with increasing antiretroviral coverage in South Africa.
Topics: Adolescent; Adult; Anti-Retroviral Agents; Efavirenz, Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination; Female; HIV Infections; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Nevirapine; Pregnancy; Pregnancy Complications, Infectious; Pregnancy Outcome; Prenatal Care; South Africa; Stavudine; Young Adult; Zidovudine | 2016 |
[Survival analysis of AIDS patients of 15 years or above years old after initiation antiretroviral treatment in Henan province during 2005 to 2014].
Topics: Acquired Immunodeficiency Syndrome; Anti-Retroviral Agents; China; Drug Therapy, Combination; Female; Humans; Lymphocyte Count; Male; Nevirapine; Proportional Hazards Models; Retrospective Studies; Risk Factors; Stavudine; Survival Analysis; Survival Rate; Zidovudine | 2015 |
Lon protease and eiF2α are involved in acute, but not prolonged, antiretroviral induced stress response in HepG2 cells.
Topics: Anti-Retroviral Agents; Chaperonin 60; Eukaryotic Initiation Factor-2; Hep G2 Cells; Hepatocytes; Humans; Mitochondria; Mitochondrial Proteins; Oxidative Stress; Protease La; Sirtuin 3; Stavudine; Stress, Physiological; Tenofovir; Zidovudine | 2016 |
The ethics of expanding access to cheaper, less effective treatments.
Topics: Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Developed Countries; Developing Countries; Drug Administration Schedule; Ethical Theory; Global Health; Health Services Accessibility; HIV Infections; Humans; South Africa; Stavudine; Tenofovir; Treatment Outcome; United States; United States Food and Drug Administration; World Health Organization; Zidovudine | 2016 |
[CLINICAL AND PHARMACOECONOMIC RESULTS OF THE USAGE OF VARIOUS HIV REVERSE TRANSCRIPTASE INHIBITORS IN THE SCHEMES OF ANTIRETROVIRAL THERAPY OF PATIENT RECEIVING THERAPY FOR THE CHRONIC HEPATITIS C VIRUS].
Topics: Adult; Alanine Transaminase; Biomarkers; Blood Platelets; CD4-Positive T-Lymphocytes; Cell Count; Coinfection; Dideoxynucleosides; Female; Genotype; Hemoglobins; Hepacivirus; Hepatitis C, Chronic; HIV Infections; HIV-1; Humans; Male; Organophosphonates; Reverse Transcriptase Inhibitors; Stavudine; Zidovudine | 2016 |
HIV therapy with unknown HBV status is responsible for higher rate of HBV genome variability in Ethiopia.
Topics: Adult; Alkynes; Antiretroviral Therapy, Highly Active; Benzoxazines; Coinfection; Cyclopropanes; DNA, Viral; Drug Resistance, Viral; Ethiopia; Female; Genetic Variation; Genome, Viral; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; HIV; HIV Infections; Humans; Immune Evasion; Lamivudine; Male; Mutation; Stavudine; Viral Load; Zidovudine | 2017 |
Adverse drug reactions associated with antiretroviral therapy in South Africa.
Topics: Adolescent; Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Dizziness; Exanthema; Female; Gynecomastia; HIV Infections; Humans; Lipodystrophy; Male; Middle Aged; Nevirapine; Peripheral Nervous System Diseases; Renal Insufficiency; Retrospective Studies; South Africa; Stavudine; Tenofovir; Zidovudine | 2016 |
Improved Adherence to Antiretroviral Therapy Observed Among HIV-Infected Children Whose Caregivers had Positive Beliefs in Medicine in Sub-Saharan Africa.
Topics: Africa South of the Sahara; Alkynes; Anti-HIV Agents; Attitude to Health; Benzoxazines; Caregivers; Child; Child, Preschool; Cyclopropanes; Dideoxynucleosides; Female; HIV Infections; Humans; Infant; Lamivudine; Linear Models; Logistic Models; Male; Medication Adherence; Multivariate Analysis; Nevirapine; Randomized Controlled Trials as Topic; Stavudine; Surveys and Questionnaires; Uganda; Zambia; Zidovudine | 2017 |
Has the phasing out of stavudine in accordance with changes in WHO guidelines led to a decrease in single-drug substitutions in first-line antiretroviral therapy for HIV in sub-Saharan Africa?
Topics: Adult; Africa South of the Sahara; Anti-Retroviral Agents; Antiretroviral Therapy, Highly Active; Drug Substitution; Drug Utilization; Female; Health Policy; HIV Infections; Humans; Male; Prospective Studies; Stavudine; Tenofovir; Zidovudine | 2017 |
Survival Outcomes in a Pediatric Antiretroviral Treatment Cohort in Southern Malawi.
Topics: Adolescent; Alkynes; Anti-HIV Agents; Benzoxazines; CD4 Lymphocyte Count; Child; Child, Preschool; Cohort Studies; Cyclopropanes; Dideoxynucleotides; Female; HIV Infections; HIV Wasting Syndrome; Humans; Infant; Lamivudine; Malawi; Male; Proportional Hazards Models; Retrospective Studies; Rural Population; Stavudine; Survival Analysis; Tuberculosis, Pulmonary; Zidovudine | 2016 |
Prevalent neuropathy in a cohort of HIV-infected Kenyan sex workers using antiretroviral drugs.
Topics: Adult; Age Factors; Anti-HIV Agents; Female; HIV Infections; Humans; Kenya; Male; Middle Aged; Polyneuropathies; Prevalence; Retrospective Studies; Risk Factors; Sex Workers; Stavudine; Tenofovir; Zidovudine | 2016 |
First-line antiretroviral drug discontinuations in children.
Topics: Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; CD4 Lymphocyte Count; Child; Child, Preschool; Cyclopropanes; Dideoxynucleosides; Drug Combinations; Follow-Up Studies; HIV; HIV Infections; Humans; Infant; Kaplan-Meier Estimate; Lopinavir; Outcome Assessment, Health Care; Proportional Hazards Models; Ritonavir; South Africa; Stavudine; Withholding Treatment; Zidovudine | 2017 |
Factors associated with loss to follow-up after occupational HIV exposure in Cape Town, South Africa: a retrospective cohort study.
Topics: Adult; Anti-HIV Agents; Emtricitabine; Female; Health Personnel; HIV Infections; Humans; Infectious Disease Transmission, Patient-to-Professional; Lamivudine; Lost to Follow-Up; Male; Occupational Exposure; Post-Exposure Prophylaxis; Retrospective Studies; South Africa; Stavudine; Tenofovir; Young Adult; Zidovudine | 2017 |
A Lower Baseline CD4/CD8 T-Cell Ratio Is Independently Associated with Immunodiscordant Response to Antiretroviral Therapy in HIV-Infected Subjects.
Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Biomarkers; CD4-CD8 Ratio; CD8-Positive T-Lymphocytes; Cell Survival; Didanosine; Female; HIV Infections; Humans; Male; Middle Aged; Receptors, CXCR4; Stavudine; T-Lymphocytes, Regulatory; Viral Load; Zalcitabine; Zidovudine | 2017 |
Multi-state models for the analysis of time-to-treatment modification among HIV patients under highly active antiretroviral therapy in Southwest Ethiopia.
Topics: Adult; Alkynes; Antiretroviral Therapy, Highly Active; Benzoxazines; Cyclopropanes; Drug Therapy, Combination; Ethiopia; Female; HIV Infections; Humans; Lamivudine; Male; Models, Theoretical; Nevirapine; Pregnancy; Retrospective Studies; Stavudine; Tenofovir; Time-to-Treatment; Treatment Failure; Zidovudine | 2017 |
Predictors of HIV virological failure and drug resistance in Chinese patients after 48 months of antiretroviral treatment, 2008-2012: a prospective cohort study.
Topics: Adult; Aged; Anti-HIV Agents; CD4 Lymphocyte Count; China; Drug Resistance, Viral; Female; HIV Infections; Humans; Logistic Models; Male; Medication Adherence; Middle Aged; Multivariate Analysis; Mutation; Prospective Studies; Risk Factors; Sentinel Surveillance; Stavudine; Sustained Virologic Response; Treatment Failure; Viral Load; Zidovudine | 2017 |
Susceptibility of Human Endogenous Retrovirus Type K to Reverse Transcriptase Inhibitors.
Topics: Anti-HIV Agents; Cell Line, Tumor; Endogenous Retroviruses; Genome, Viral; Humans; Integrase Inhibitors; Lamivudine; Protease Inhibitors; Reverse Transcriptase Inhibitors; Reverse Transcription; Stavudine; Virus Replication; Zidovudine | 2017 |
Five-year trends in treatment changes in an adult cohort of HIV/AIDS patients in Ghana: a retrospective cohort study.
Topics: Acquired Immunodeficiency Syndrome; Adult; Aged; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Cohort Studies; Female; Ghana; HIV Infections; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Retrospective Studies; Stavudine; Tenofovir; Young Adult; Zidovudine | 2017 |
Community outreach programs and major adherence lapses with antiretroviral therapy in rural Kakamega, Kenya.
Topics: Adolescent; Adult; Anti-HIV Agents; Community Health Workers; Community-Institutional Relations; Female; HIV Infections; House Calls; Humans; Kenya; Male; Medication Adherence; Middle Aged; Rural Population; Stavudine; Survival Analysis; Tenofovir; Young Adult; Zidovudine | 2018 |
The incidence of first-line antiretroviral treatment changes and related factors among HIV-infected sex workers in Nairobi, Kenya.
Topics: Adult; Anti-HIV Agents; Female; Follow-Up Studies; HIV Infections; Humans; Incidence; Kenya; Male; Middle Aged; Retrospective Studies; Sex Workers; Stavudine; Tenofovir; Time Factors; Zidovudine | 2017 |
Motives for change of first-line antiretroviral therapy regimens in an unselected cohort of HIV/AIDS patients at a major referral centre in South-west Cameroon.
Topics: Adult; Anti-HIV Agents; Cameroon; Cohort Studies; Cross-Sectional Studies; Drug Combinations; Drug Substitution; Female; HIV Infections; Humans; Lamivudine; Male; Middle Aged; Nevirapine; Referral and Consultation; Stavudine; Zidovudine | 2017 |
Long-term viral suppression and immune recovery during first-line antiretroviral therapy: a study of an HIV-infected adult cohort in Hanoi, Vietnam.
Topics: Adolescent; Adult; Aged; Alkynes; Anti-HIV Agents; Benzoxazines; CD4 Lymphocyte Count; Cohort Studies; Cyclopropanes; Female; HIV Infections; Humans; Longitudinal Studies; Male; Middle Aged; Nevirapine; Stavudine; Time Factors; Vietnam; Viral Load; Young Adult; Zidovudine | 2017 |
Mitochondrial DNA content of peripheral blood mononuclear cells in ART untreated & stavudine/zidovudine treated HIV-1-infected patients.
Topics: Adult; Antiretroviral Therapy, Highly Active; DNA, Mitochondrial; Female; HIV Infections; HIV-1; Humans; Leukocytes, Mononuclear; Male; Middle Aged; Reverse Transcriptase Inhibitors; Stavudine; Zidovudine | 2018 |
Adherence, virological outcome, and drug resistance in Chinese HIV patients receiving first-line antiretroviral therapy from 2011 to 2015.
Topics: Adult; Anti-HIV Agents; China; Drug Resistance, Viral; Female; HIV; HIV Infections; Humans; Lamivudine; Male; Medication Adherence; Middle Aged; Retrospective Studies; Stavudine; Sustained Virologic Response; Tenofovir; Zidovudine | 2018 |
LINE1 Derepression in Aged Wild-Type and SIRT6-Deficient Mice Drives Inflammation.
Topics: Age Factors; Animals; Dideoxynucleotides; Female; Inflammation; Male; Mice; Mice, Inbred Strains; Mice, Knockout; RNA-Binding Proteins; Sirtuins; Stavudine; Thymine Nucleotides; Zidovudine | 2019 |
HIV-1 drug resistance testing is essential for heavily-treated patients switching from first- to second-line regimens in resource-limited settings: evidence from routine clinical practice in Cameroon.
Topics: Adolescent; Adult; Anti-HIV Agents; Cameroon; Child; Drug Resistance, Viral; Female; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Male; Reverse Transcriptase Inhibitors; Ritonavir; Stavudine; Tenofovir; Young Adult; Zidovudine | 2019 |
Incidence and types of HIV-1 drug resistance mutation among patients failing first-line antiretroviral therapy.
Topics: Adult; Alkynes; Antiretroviral Therapy, Highly Active; Antiviral Agents; Benzoxazines; Cyclopropanes; Drug Resistance, Viral; Female; HIV Infections; HIV-1; Humans; Incidence; Lamivudine; Male; Middle Aged; Mutation; Nevirapine; Stavudine; Tenofovir; Treatment Failure; Viral Load; Zidovudine | 2019 |
Structural dynamics and susceptibility of anti-HIV drugs against HBV reverse transcriptase.
Topics: Anti-HIV Agents; Hepatitis B virus; HIV Infections; Humans; Reverse Transcriptase Inhibitors; Stavudine; Zidovudine | 2021 |
Zidovudine and lamivudine reach higher concentrations in ventricular than in lumbar human cerebrospinal fluid.
Topics: Adult; AIDS Dementia Complex; Anti-HIV Agents; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Lamivudine; Male; RNA, Viral; Spinal Puncture; Stavudine; Viral Load; Zidovudine | 2020 |
Sustainable Protocol for the Synthesis of 2',3'-Dideoxynucleoside and 2',3'-Didehydro-2',3'-dideoxynucleoside Derivatives.
Topics: Anti-HIV Agents; Didanosine; Dideoxynucleosides; Stavudine; Zalcitabine; Zidovudine | 2022 |
The antiretroviral agents azidothymidine, stavudine, and didanosine have the identical mutational fingerprint in the rpoB region of Escherichia coli.
Topics: Anti-HIV Agents; Anti-Retroviral Agents; Didanosine; DNA-Directed RNA Polymerases; Escherichia coli; Escherichia coli Proteins; HIV Reverse Transcriptase; Mutation; Stavudine; Zidovudine | 2022 |
REVERSIBILITY OF LIPOATROPHY IN HIV-INFECTED PATIENTS TAKING ANTIRETROVIRAL THERAPY: A COHORT STUDY WITH ULTRASOUND ASSESSMENT.
Topics: Cohort Studies; HIV Infections; HIV-Associated Lipodystrophy Syndrome; Humans; Longitudinal Studies; Prospective Studies; Stavudine; Zidovudine | 2022 |