Compounds > zidovudine
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zidovudine and r-82913

zidovudine has been researched along with r-82913 in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's16 (94.12)18.2507
2000's1 (5.88)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Breslin, HJ; De Clercq, E; Diamond, CJ; Grous, PP; Ho, CY; Kukla, MJ; Miranda, M; Pauwels, R; Rodgers, JD; Sherrill, RG1
Andreola, ML; Aubertin, AM; Bisagni, E; Dollé, V; Fan, E; Jamieson, G; Kirn, A; Nguyen, CH; Tarrago-Litvak, L1
Antonenko, SV; Chentsova, NP; Kukhar, VP; Luik, AI; Poda, GI; Tetko, IV1
Balani, SK; Ciccarone, TM; Condra, JH; Emini, EA; Goldman, ME; Greenlee, WJ; Kauffman, LR; MacTough, SC; Rooney, CS; Williams, TM1
Breslin, HJ; De Clercq, E; Diamond, CJ; Grous, PP; Ho, CY; Ho, W; Kukla, MJ; Ludovici, DW; Miranda, M; Rodgers, JD1
Bell, FW; Cantrell, AS; Högberg, M; Jaskunas, SR; Johansson, NG; Jordan, CL; Kinnick, MD; Lind, P; Morin, JM; Noréen, R1
Andreola, ML; Aubertin, AM; Bisagni, E; Dollé, V; Kirn, A; Legraverend, M; Nguyen, CH; Tarrago-Litvak, L; Ventura, M1
Larder, BA1
Andries, K; De Clercq, E; Debyser, Z; Pauwels, R1
Balzarini, J; Bergamini, A; Calio, R; De Clercq, E; Milanese, G; Pauwels, R; Perno, CF; Rocchi, G; Yarchoan, R1
Anné, J; de Clercq, E; de Vreese, K; Debyser, Z; Desmyter, J; Pauwels, R; Vandamme, AM1
Andries, K; Buckheit, RW; Chirigos, MA; Germany, JM; Janssen, PA; Pauwels, R; Ross, LJ; Shannon, WM; White, EL1
Andries, K; Ganser, A; Geissler, RG; Hoelzer, D; Kojouharoff, G; Ottmann, OG; Reutzel, P; Schellekens, K1
Allen, LB; Buckheit, RW; Chirigos, MA; Germany-Decker, J; Hollingshead, MG; Janssen, PA; Shannon, WM1
Bakhanashvili, M; Hizi, A1
Hansen, JE; Mathiesen, LR; Nielsen, C; Nielsen, JO; Sørensen, AM1
Balzarini, J; De Clercq, E; Kleim, JP; Pelemans, H; Riess, G; Roesner, M; Winkler, I1

Reviews

1 review(s) available for zidovudine and r-82913

ArticleYear
Specific HIV-1 reverse transcriptase inhibitors.
    Journal of enzyme inhibition, 1992, Volume: 6, Issue:1

    Topics: Antiviral Agents; Benzodiazepines; HIV Reverse Transcriptase; HIV-1; Imidazoles; Models, Genetic; Reverse Transcriptase Inhibitors; Thymine; Transcription, Genetic; Zidovudine

1992

Other Studies

16 other study(ies) available for zidovudine and r-82913

ArticleYear
Synthesis and anti-HIV-1 activity of 4,5,6,7-tetrahydro-5-methylimidazo[4,5,1-jk][1,4]benzodiazepin-2(1H)-on e (TIBO) derivatives. 2.
    Journal of medicinal chemistry, 1991, Volume: 34, Issue:11

    Topics: Antiviral Agents; Benzodiazepines; HIV-1; Imidazoles; Microbial Sensitivity Tests; Structure-Activity Relationship; Virus Replication

1991
A new series of pyridinone derivatives as potent non-nucleoside human immunodeficiency virus type 1 specific reverse transcriptase inhibitors.
    Journal of medicinal chemistry, 1995, Nov-10, Volume: 38, Issue:23

    Topics: Antiviral Agents; HIV Reverse Transcriptase; HIV-1; HIV-2; Kinetics; Molecular Structure; Pyridones; Recombinant Proteins; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Structure-Activity Relationship; Virus Replication

1995
HIV-1 reverse transcriptase inhibitor design using artificial neural networks.
    Journal of medicinal chemistry, 1994, Aug-05, Volume: 37, Issue:16

    Topics: Algorithms; Cell Line; Drug Design; HIV Reverse Transcriptase; HIV-1; Humans; Molecular Structure; Neural Networks, Computer; Pyrimidines; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; T-Lymphocytes; Zidovudine

1994
5-chloro-3-(phenylsulfonyl)indole-2-carboxamide: a novel, non-nucleoside inhibitor of HIV-1 reverse transcriptase.
    Journal of medicinal chemistry, 1993, Apr-30, Volume: 36, Issue:9

    Topics: Animals; Antiviral Agents; Base Sequence; Biological Availability; HIV; HIV Reverse Transcriptase; HIV-1; Indoles; Macaca mulatta; Molecular Sequence Data; Molecular Structure; Reverse Transcriptase Inhibitors; Sulfoxides

1993
Synthesis and anti-HIV-1 activity of 4,5,6,7-tetrahydro-5-methylimidazo-[4,5,1-jk][1,4]benzodiazepin- 2(1H)-one (TlBO) derivatives. 4.
    Journal of medicinal chemistry, 1995, Mar-03, Volume: 38, Issue:5

    Topics: Antiviral Agents; Benzodiazepines; Cell Line; Cytopathogenic Effect, Viral; HIV-1; Imidazoles; Structure-Activity Relationship; Virus Replication

1995
Phenethylthiazolethiourea (PETT) compounds, a new class of HIV-1 reverse transcriptase inhibitors. 1. Synthesis and basic structure-activity relationship studies of PETT analogs.
    Journal of medicinal chemistry, 1995, Dec-08, Volume: 38, Issue:25

    Topics: Animals; Antiviral Agents; Cell Line; HIV-1; Humans; Isothiocyanates; Rats; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Thiazoles; Thiourea

1995
Synthesis and antiviral activity of 4-benzyl pyridinone derivatives as potent and selective non-nucleoside human immunodeficiency virus type 1 reverse transcriptase inhibitors.
    Journal of medicinal chemistry, 2000, Oct-19, Volume: 43, Issue:21

    Topics: Anti-HIV Agents; Cell Line; Cells, Cultured; Drug Resistance, Microbial; HIV-1; Humans; Pyridones; Recombinant Proteins; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Structure-Activity Relationship; Virion; Virus Replication

2000
3'-Azido-3'-deoxythymidine resistance suppressed by a mutation conferring human immunodeficiency virus type 1 resistance to nonnucleoside reverse transcriptase inhibitors.
    Antimicrobial agents and chemotherapy, 1992, Volume: 36, Issue:12

    Topics: Antiviral Agents; Base Sequence; Benzodiazepines; Cloning, Molecular; Drug Resistance, Microbial; HIV Reverse Transcriptase; HIV-1; Humans; Imidazoles; Molecular Sequence Data; Mutagenesis, Site-Directed; Nevirapine; Pyridines; Reverse Transcriptase Inhibitors; Zidovudine

1992
Different pattern of activity of inhibitors of the human immunodeficiency virus in lymphocytes and monocyte/macrophages.
    Antiviral research, 1992, Volume: 17, Issue:4

    Topics: Adenine; Antibodies, Viral; Antiviral Agents; Benzodiazepines; CD4 Antigens; Cytokines; Didanosine; Doxorubicin; Drug Interactions; HIV; HIV Infections; Humans; Imidazoles; Leukocytes, Mononuclear; Lymphocytes; Macrophages; Monocytes; Organ Specificity; Organophosphonates; Zalcitabine; Zidovudine

1992
Resistance of human immunodeficiency virus type 1 reverse transcriptase to TIBO derivatives induced by site-directed mutagenesis.
    Virology, 1992, Volume: 188, Issue:2

    Topics: Antiviral Agents; Base Sequence; Benzodiazepines; Binding Sites; Deoxyguanine Nucleotides; Dideoxynucleotides; HIV Reverse Transcriptase; HIV-1; Imidazoles; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Structure-Activity Relationship; Uracil; Zidovudine

1992
A TIBO derivative, R82913, is a potent inhibitor of HIV-1 reverse transcriptase with heteropolymer templates.
    Antiviral research, 1991, Volume: 16, Issue:3

    Topics: Base Sequence; Benzodiazepines; HIV-1; HIV-2; Imidazoles; Molecular Sequence Data; Retroviridae Proteins; Reverse Transcriptase Inhibitors; Templates, Genetic; Zidovudine

1991
TIBO R82913, a new HIV-1 inhibiting agent, does not inhibit hematopoietic progenitor cells.
    AIDS research and human retroviruses, 1991, Volume: 7, Issue:12

    Topics: Acquired Immunodeficiency Syndrome; Adult; Antiviral Agents; Benzodiazepines; Colony-Forming Units Assay; Erythroid Precursor Cells; Hematopoietic Stem Cells; Humans; Imidazoles; Zidovudine

1991
Differential antiviral activity of two TIBO derivatives against the human immunodeficiency and murine leukemia viruses alone and in combination with other anti-HIV agents.
    AIDS research and human retroviruses, 1993, Volume: 9, Issue:11

    Topics: Animals; Antiviral Agents; Benzodiazepines; Cell Line; Didanosine; Drug Synergism; HIV Reverse Transcriptase; HIV-1; HIV-2; Humans; Imidazoles; Mice; Rauscher Virus; Reverse Transcriptase Inhibitors; Virus Replication; Zidovudine

1993
Interaction of the reverse transcriptase of human immunodeficiency virus type 1 with DNA.
    Biochemistry, 1994, Oct-11, Volume: 33, Issue:40

    Topics: Antiviral Agents; Autoradiography; Base Sequence; Benzodiazepines; Binding, Competitive; Dideoxynucleotides; DNA-Binding Proteins; DNA, Viral; Electrophoresis, Polyacrylamide Gel; HIV Reverse Transcriptase; HIV-1; Imidazoles; Molecular Sequence Data; Oligodeoxyribonucleotides; Quinolones; Recombinant Proteins; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Thymine Nucleotides; Zidovudine

1994
Evaluation of the combination effect of different antiviral compounds against HIV in vitro.
    Scandinavian journal of infectious diseases, 1993, Volume: 25, Issue:3

    Topics: Antiviral Agents; Benzodiazepines; Didanosine; Dideoxynucleosides; Drug Combinations; Drug Evaluation; Drug Synergism; HIV; Humans; Imidazoles; Microbial Sensitivity Tests; Reverse Transcriptase Inhibitors; Stavudine; Zidovudine

1993
Retention of marked sensitivity to (S)-4-isopropoxycarbonyl-6-methoxy-3-(methylthiomethyl)-3,4-di hydroquin oxaline-2(1H)-thione (HBY 097) by an azidothymidine (AZT)-resistant human immunodeficiency virus type 1 (HIV-1) strain subcultured in the combined
    Biochemical pharmacology, 1998, Mar-01, Volume: 55, Issue:5

    Topics: Anti-HIV Agents; Antiviral Agents; Benzodiazepines; Cell Line; Delavirdine; Drug Resistance, Microbial; Furans; HIV Reverse Transcriptase; HIV-1; Humans; Imidazoles; Lamivudine; Microbial Sensitivity Tests; Mutagenesis, Site-Directed; Mutation; Nevirapine; Quinoxalines; Recombinant Proteins; Reverse Transcriptase Inhibitors; Zidovudine

1998