zidovudine has been researched along with nsc 614846 in 18 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (11.11) | 18.7374 |
| 1990's | 14 (77.78) | 18.2507 |
| 2000's | 1 (5.56) | 29.6817 |
| 2010's | 1 (5.56) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hua, M; Vince, R | 1 |
| Bennett, M; Chu, CK; Jin, Y; Rapp, KL; Schinazi, RF; Wang, J | 1 |
| Du, DL; Grieshaber, CK; Murphy, MJ; Volpe, DA | 1 |
| Cameron, JM; Figueiredo, HT; Mo, CL; Orr, DC; Penn, CR | 1 |
| Cameron, JM; Coates, JA; Inggall, HJ; Pearson, BA; Penn, CR; Storer, R; Williamson, C | 1 |
| Carter, SG; Kurtzberg, J | 1 |
| Carter, SG; Kessler, JA; Rankin, CD | 1 |
| Macy, LJ; McCaleb, G; Parker, WB; Secrist, JA; Shaddix, SC; Shannon, WM; Vince, R; White, EL | 1 |
| Brownell, J; Daluge, S; Hua, M; Kiser, R; Lavelle, GC; Lee, FC; Qualls, J; Shannon, WM; Vince, R; Weislow, OS | 1 |
| Parker, WB; Ross, LJ; Shannon, WM; White, EL | 1 |
| Bennett, LL; Bowdon, BJ; Parker, WB; Rose, LM; Shaddix, SC; Shannon, WM; Vince, R | 1 |
| Carter, SG; Kessler, JA; Kurtzberg, J; Pagano, JS; Rankin, CD; Smith, MS | 1 |
| Alberdi, E; Martinez-Irujo, JJ; Santiago, E; Villahermosa, ML | 1 |
| Akimov, SS; Bolsheva, NL; Chernov, DN; Krayevsky, AA; Yegorov, YE; Zelenin, AV | 1 |
| Akhmalisheva, AK; Akimov, SS; Chernov, DN; Semenova, IV; Shinkarev, DB; Smirnova, YB; Yegorov, YE; Yegorova, IN; Zelenin, AV | 1 |
| Kato, K; Miyasaka, T; Suzuki, H; Tanaka, H | 1 |
| Mickle, T; Nair, V | 1 |
| Betancor, G; Garriga, C; MartÃnez, MA; Martinez-Picado, J; Menéndez-Arias, L; Nevot, M; Puertas, MC | 1 |
18 other study(ies) available for zidovudine and nsc 614846
| Article | Year |
|---|---|
Synthesis and anti-HIV activity of carbocyclic 2',3'-didehydro-2',3'-dideoxy 2,6-disubstituted purine nucleosides.
Topics: Animals; Antiviral Agents; Chemical Phenomena; Chemistry; Cytopathogenic Effect, Viral; Dideoxyadenosine; Dideoxynucleosides; HIV; Leukemia P388; Molecular Structure; Purine Nucleosides; Structure-Activity Relationship; Tumor Cells, Cultured; Virus Replication; Zidovudine | 1990 |
Synthesis, antiviral activity, and mechanism of drug resistance of D- and L-2',3'-didehydro-2',3'-dideoxy-2'-fluorocarbocyclic nucleosides.
Topics: Adenine; Anti-HIV Agents; Cells, Cultured; Cyclopentanes; Dideoxynucleosides; Drug Resistance, Viral; HIV Reverse Transcriptase; HIV-1; Humans; Hydrogen Bonding; Lamivudine; Leukocytes, Mononuclear; Models, Molecular; Molecular Conformation; Mutation; Stereoisomerism; Structure-Activity Relationship | 2005 |
In vitro toxicity of 3'-azido-3'-deoxythymidine, carbovir and 2',3'-didehydro-2',3'-dideoxythymidine to human and murine haematopoietic progenitor cells.
Topics: Animals; Antiviral Agents; Bone Marrow Cells; Cell Division; Cells, Cultured; Colony-Forming Units Assay; Dideoxynucleosides; Dose-Response Relationship, Drug; Hematopoietic Stem Cells; Humans; In Vitro Techniques; Mice; Mice, Inbred Strains; Stavudine; Zidovudine | 1992 |
DNA chain termination activity and inhibition of human immunodeficiency virus reverse transcriptase by carbocyclic 2',3'-didehydro-2',3'-dideoxyguanosine triphosphate.
Topics: Antiviral Agents; Base Sequence; Dideoxynucleosides; DNA, Viral; Escherichia coli; HIV Reverse Transcriptase; HIV-1; Kinetics; Molecular Sequence Data; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Transcription, Genetic; Zidovudine | 1992 |
Carbovir: the (-) enantiomer is a potent and selective antiviral agent against human immunodeficiency virus in vitro.
Topics: CD4-Positive T-Lymphocytes; Cell Line; Cell Survival; Dideoxynucleosides; Giant Cells; HIV; Humans; Viral Core Proteins; Virus Replication; Zalcitabine; Zidovudine | 1991 |
Differential toxicity of carbovir and AZT to human bone marrow hematopoietic progenitor cells in vitro.
Topics: Bone Marrow Cells; Cell Division; Colony-Forming Units Assay; Dideoxynucleosides; Dose-Response Relationship, Drug; Erythroid Precursor Cells; Granulocytes; Hematopoietic Stem Cells; Humans; Macrophages; Megakaryocytes; Zidovudine | 1990 |
Activities of (-)-carbovir and 3'-azido-3'-deoxythymidine against human immunodeficiency virus in vitro.
Topics: Antiviral Agents; Cell Line; Cell Survival; Dideoxynucleosides; HIV; Humans; Virus Replication; Zidovudine | 1990 |
Comparison of the effect of Carbovir, AZT, and dideoxynucleoside triphosphates on the activity of human immunodeficiency virus reverse transcriptase and selected human polymerases.
Topics: Deoxyguanine Nucleotides; Dideoxynucleosides; Dideoxynucleotides; DNA Primase; HIV; Humans; Nucleic Acid Synthesis Inhibitors; Reverse Transcriptase Inhibitors; RNA Nucleotidyltransferases; Thymine Nucleotides; Zidovudine | 1989 |
Potent and selective activity of a new carbocyclic nucleoside analog (carbovir: NSC 614846) against human immunodeficiency virus in vitro.
Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Cytopathogenic Effect, Viral; Dideoxynucleosides; HIV; Molecular Structure; Structure-Activity Relationship; Virus Replication; Zalcitabine; Zidovudine | 1988 |
Lack of synergy in the inhibition of HIV-1 reverse transcriptase by combinations of the 5'-triphosphates of various anti-HIV nucleoside analogs.
Topics: Antiviral Agents; Base Sequence; Deoxyadenine Nucleotides; Dideoxynucleosides; Dideoxynucleotides; DNA-Directed DNA Polymerase; DNA, Viral; Drug Synergism; HIV Reverse Transcriptase; Molecular Sequence Data; Reverse Transcriptase Inhibitors; Thymine Nucleotides; Zidovudine | 1993 |
Metabolism of carbovir, a potent inhibitor of human immunodeficiency virus type 1, and its effects on cellular metabolism.
Topics: Antiviral Agents; Cell Line; Dideoxynucleosides; DNA; Drug Synergism; Half-Life; HIV-1; Humans; Mycophenolic Acid; RNA; Zidovudine | 1993 |
Evaluation of synergy between carbovir and 3'-azido-2',3'-deoxythymidine for inhibition of human immunodeficiency virus type 1.
Topics: Antiviral Agents; Cell Line; Dideoxynucleosides; Drug Synergism; HIV-1; Humans; Viral Plaque Assay; Virus Replication; Zidovudine | 1993 |
A checkerboard method to evaluate interactions between drugs.
Topics: Alcohol Dehydrogenase; Animals; Data Interpretation, Statistical; Dideoxynucleosides; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; HIV-1; Horses; Humans; Zidovudine | 1996 |
Reverse transcriptase inhibitors suppress telomerase function and induce senescence-like processes in cultured mouse fibroblasts.
Topics: 3T3 Cells; Animals; Antiviral Agents; Base Sequence; Cell Division; Cell Line, Transformed; Cell Transformation, Viral; Cells, Cultured; Cellular Senescence; Dideoxynucleosides; Dose-Response Relationship, Drug; Drug Resistance; Fibroblasts; Mice; Mice, Inbred CBA; Mitosis; Molecular Sequence Data; Polyploidy; Reverse Transcriptase Inhibitors; Simian virus 40; Telomerase; Zidovudine | 1996 |
Blockade of telomerase function by nucleoside analogs.
Topics: Animals; Cell Division; Cell Line; Cell Line, Transformed; Cells, Cultured; Cellular Senescence; Clone Cells; Dideoxynucleosides; Fetus; Fibroblasts; Humans; Kinetics; Mice; Mice, Inbred CBA; Rats; Telomerase; Zidovudine | 1997 |
Asymmetric synthesis of 4'-alpha-alkylcarbovir derivatives.
Topics: Alkylation; Anti-HIV Agents; Dideoxynucleosides; HIV; Indicators and Reagents; Molecular Structure; Zidovudine | 1997 |
Correlation of anti-HIV activity with structure: use of electrostatic potential and conformational analysis.
Topics: Adenine; Anti-HIV Agents; Computer Simulation; Deoxyribonucleotides; Dideoxynucleosides; Hydrogen Bonding; Isomerism; Models, Chemical; Models, Molecular; Static Electricity; Structure-Activity Relationship; Zidovudine | 1999 |
Mechanisms involved in the selection of HIV-1 reverse transcriptase thumb subdomain polymorphisms associated with nucleoside analogue therapy failure.
Topics: Cell Line; Cells, Cultured; Dideoxynucleosides; Drug Resistance, Viral; HIV Infections; HIV Reverse Transcriptase; Humans; Polymorphism, Genetic; Reverse Transcriptase Inhibitors; Stavudine; Virus Replication; Zidovudine | 2010 |