Compounds > zidovudine
Page last updated: 2024-08-23

zidovudine and hymecromone

zidovudine has been researched along with hymecromone in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (66.67)29.6817
2010's1 (16.67)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Strassburg, CP; Tukey, RH1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Elliot, DJ; Gaganis, P; Knights, KM; Mackenzie, PI; Miners, JO; Rowland, A1
Galetin, A; Houston, JB; Mackenzie, PI; Miners, JO; Uchaipichat, V; Williams, JA1
Finel, M; Manevski, N; Moreolo, PS; Yli-Kauhaluoma, J1
Chau, N; McKinnon, RA; Miners, JO; Nair, PC1

Reviews

1 review(s) available for zidovudine and hymecromone

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic

2000

Other Studies

5 other study(ies) available for zidovudine and hymecromone

ArticleYear
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Binding of inhibitory fatty acids is responsible for the enhancement of UDP-glucuronosyltransferase 2B7 activity by albumin: implications for in vitro-in vivo extrapolation.
    The Journal of pharmacology and experimental therapeutics, 2007, Volume: 321, Issue:1

    Topics: Albumins; Animals; Anti-HIV Agents; Blotting, Western; Cattle; Chromatography, High Pressure Liquid; Data Interpretation, Statistical; Fatty Acids; Glucuronides; Glucuronosyltransferase; Humans; Hymecromone; In Vitro Techniques; Kinetics; Microsomes; Protein Binding; Recombinant Proteins; Serum Albumin; Serum Albumin, Bovine; Zidovudine

2007
Kinetic modeling of the interactions between 4-methylumbelliferone, 1-naphthol, and zidovudine glucuronidation by udp-glucuronosyltransferase 2B7 (UGT2B7) provides evidence for multiple substrate binding and effector sites.
    Molecular pharmacology, 2008, Volume: 74, Issue:4

    Topics: Antimetabolites; Binding Sites; Cell Line; Dose-Response Relationship, Drug; Drug Interactions; Glucuronides; Glucuronosyltransferase; Humans; Hymecromone; Indicators and Reagents; Kidney; Kinetics; Naphthols; Substrate Specificity; Transfection; Zidovudine

2008
Bovine serum albumin decreases Km values of human UDP-glucuronosyltransferases 1A9 and 2B7 and increases Vmax values of UGT1A9.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:11

    Topics: Animals; Catechols; Cattle; Cell Membrane; Drug Interactions; Glucuronides; Glucuronosyltransferase; Humans; Hymecromone; Kinetics; Microsomes, Liver; Nitriles; Recombinant Proteins; Serum Albumin, Bovine; UDP-Glucuronosyltransferase 1A9; Uridine Diphosphate Glucuronic Acid; Zidovudine

2011
Arginine-259 of UGT2B7 Confers UDP-Sugar Selectivity.
    Molecular pharmacology, 2020, Volume: 98, Issue:6

    Topics: Arginine; Binding Sites; Coenzymes; Crystallography, X-Ray; Glucosyltransferases; Glucuronides; Glucuronosyltransferase; Glycosides; HEK293 Cells; Humans; Hymecromone; Medicago truncatula; Molecular Dynamics Simulation; Morphine; Mutagenesis, Site-Directed; Mutation; Plant Proteins; Sequence Homology, Amino Acid; Substrate Specificity; Uridine Diphosphate Glucuronic Acid; Zidovudine

2020