Page last updated: 2024-08-23

zidovudine and guanosine

zidovudine has been researched along with guanosine in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's7 (50.00)18.2507
2000's7 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Goudgaon, NM; Schinazi, RF1
Hayakawa, M; Ogawa, T; Ozawa, T; Sugiyama, S; Tanaka, M1
Freeman, GA; Rideout, JL; Shaver, SR; Short, SA1
Black, PL; McKinnon, KM; Ussery, MA; Wooden, SL1
Cass, CE; Elliott, JF; Huang, MY; Ritzel, MW; Yao, SY; Young, JD1
Ahle, D; Bushnell, S; Chang, C; Collins, ML; Detmer, J; Fine, E; Ho, DD; Horn, T; Irvine, B; Kolberg, J; Shen, LP; Tyner, D; Urdea, MS; Zayati, C1
Back, DJ; Barry, MG; Henry-Mowatt, JS; Hoggard, PG; Kewn, S; Sales, SD; Veal, GJ1
Bendayan, R; Hong, M; Schlichter, L1
Bazmi, HZ; Cavalcanti, SC; Chu, CK; Hammond, JL; Mellors, JW; Schinazi, RF1
Borroto-Esoda, K; Chong, Y; Chu, CK; Furman, PA; Schinazi, RF1
Anderson, KS; Feng, JY; Furman, PA; Jeffrey, JL; Qi, CC1
Parker, WB; Rose, JD; Secrist, JA1
Boojamra, CG; Cihlar, T; Douglas, J; Grant, D; Hui, H; Lin, KY; Mackman, RL; Petrakovsky, O; Prasad, V; Ray, AS1
Boojamra, CG; Cihlar, T; Douglas, J; Grant, D; Kim, CU; Mackman, RL; Markevitch, DY; Prasad, V; Ray, AS1

Other Studies

14 other study(ies) available for zidovudine and guanosine

ArticleYear
Activity of acyclic 6-(phenylselenenyl)pyrimidine nucleosides against human immunodeficiency viruses in primary lymphocytes.
    Journal of medicinal chemistry, 1991, Volume: 34, Issue:11

    Topics: Animals; Antiviral Agents; HIV-1; HIV-2; Humans; Lymphocytes; Pyrimidine Nucleosides; RNA-Directed DNA Polymerase; Structure-Activity Relationship; Vero Cells

1991
Massive conversion of guanosine to 8-hydroxy-guanosine in mouse liver mitochondrial DNA by administration of azidothymidine.
    Biochemical and biophysical research communications, 1991, Apr-15, Volume: 176, Issue:1

    Topics: Animals; Chromatography, High Pressure Liquid; DNA, Mitochondrial; Dose-Response Relationship, Drug; Guanosine; Mass Spectrometry; Mice; Mice, Inbred Strains; Mitochondria, Liver; Reference Values; Superoxides; Zidovudine

1991
2-amino-9-(3-azido-2,3-dideoxy-beta-D-erythro-pentofuranosyl)-6-substituted-9H-purines: synthesis and anti-HIV activity.
    Bioorganic & medicinal chemistry, 1995, Volume: 3, Issue:4

    Topics: Antiviral Agents; Cell Line, Transformed; Cytopathogenic Effect, Viral; Dideoxynucleosides; Guanosine; HIV-1; Humans; Lactobacillus; Pentosyltransferases; Purines; Structure-Activity Relationship; T-Lymphocytes; Thymidine; Zidovudine

1995
Antiviral activity of biological response modifiers in a murine model of AIDS. Requirement for augmentation of natural killer cell activity and synergy with oral AZT.
    International journal of immunopharmacology, 1996, Volume: 18, Issue:11

    Topics: Acquired Immunodeficiency Syndrome; Acridines; Animals; Antibodies; Antiviral Agents; Asialoglycoproteins; Disease Models, Animal; Drug Synergism; Female; G(M1) Ganglioside; Glucans; Guanosine; Immunologic Factors; In Vitro Techniques; Killer Cells, Natural; Lymphocyte Depletion; Mice; Mice, Inbred BALB C; Poly I-C; Poly U; Pyran Copolymer; Rabbits; Rauscher Virus; Specific Pathogen-Free Organisms; Viral Plaque Assay; Zidovudine

1996
Molecular cloning and functional expression of cDNAs encoding a human Na+-nucleoside cotransporter (hCNT1).
    The American journal of physiology, 1997, Volume: 272, Issue:2 Pt 1

    Topics: Adenosine; Amino Acid Sequence; Animals; Biological Transport; Carrier Proteins; Chromosome Mapping; Cloning, Molecular; Deoxyadenosines; DNA, Complementary; Female; Guanosine; Humans; Kinetics; Molecular Sequence Data; Oocytes; Rats; Recombinant Proteins; Symporters; Xenopus; Zidovudine

1997
A branched DNA signal amplification assay for quantification of nucleic acid targets below 100 molecules/ml.
    Nucleic acids research, 1997, Aug-01, Volume: 25, Issue:15

    Topics: Adenosine; Anti-HIV Agents; Cytidine; DNA; DNA, Viral; Drug Therapy, Combination; Guanosine; HIV; HIV Infections; Humans; Isoquinolines; Lamivudine; Nelfinavir; Nucleic Acid Hybridization; RNA, Viral; Sulfonic Acids; Zidovudine

1997
Intracellular activation of 2',3'-dideoxyinosine and drug interactions in vitro.
    AIDS research and human retroviruses, 1999, Jun-10, Volume: 15, Issue:9

    Topics: Anti-HIV Agents; Deoxyadenine Nucleotides; Didanosine; Dideoxynucleotides; Drug Interactions; Guanosine; Humans; Hydroxyurea; Inosine; Intracellular Fluid; Lamivudine; Pentoxifylline; Stavudine; U937 Cells; Zidovudine

1999
A Na(+)-dependent nucleoside transporter in microglia.
    The Journal of pharmacology and experimental therapeutics, 2000, Volume: 292, Issue:1

    Topics: Adenosine; Animals; Carrier Proteins; Cell Size; Cells, Cultured; Cytidine; Dideoxynucleosides; Dose-Response Relationship, Drug; Guanosine; Membrane Proteins; Microglia; Nucleic Acid Probes; Nucleoside Transport Proteins; Rats; Rats, Wistar; Sodium; Thymidine; Time Factors; Uridine; Zidovudine

2000
In vitro selection of mutations in the human immunodeficiency virus type 1 reverse transcriptase that decrease susceptibility to (-)-beta-D-dioxolane-guanosine and suppress resistance to 3'-azido-3'-deoxythymidine.
    Antimicrobial agents and chemotherapy, 2000, Volume: 44, Issue:7

    Topics: Cells, Cultured; Computer Simulation; Dioxolanes; Drug Resistance, Microbial; Guanosine; HIV Reverse Transcriptase; HIV-1; Humans; Microbial Sensitivity Tests; Mutation; Reverse Transcriptase Inhibitors; Zidovudine

2000
Molecular mechanism of DApd/DXG against zidovudine- and lamivudine- drug resistant mutants: a molecular modelling approach.
    Antiviral chemistry & chemotherapy, 2002, Volume: 13, Issue:2

    Topics: Anti-HIV Agents; Binding Sites; Dioxolanes; Drug Resistance; Guanosine; HIV-1; Lamivudine; Models, Molecular; Mutation, Missense; Protein Binding; Purine Nucleosides; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Structure-Activity Relationship; Zidovudine

2002
Dioxolane guanosine 5'-triphosphate, an alternative substrate inhibitor of wild-type and mutant HIV-1 reverse transcriptase. Steady state and pre-steady state kinetic analyses.
    The Journal of biological chemistry, 2003, May-23, Volume: 278, Issue:21

    Topics: Acquired Immunodeficiency Syndrome; Cytidine Triphosphate; Deoxycytidine Monophosphate; Deoxyguanine Nucleotides; Dideoxynucleotides; Dioxolanes; DNA, Viral; Drug Resistance, Viral; Guanosine; Guanosine Triphosphate; HIV Reverse Transcriptase; HIV-1; Lamivudine; Mutation; Reverse Transcriptase Inhibitors; Substrate Specificity; Thymidine Monophosphate; Thymine Nucleotides; Zidovudine

2003
Bis(tBuSATE) phosphotriester prodrugs of 8-azaguanosine and 6-methylpurine riboside; bis(pom) phosphotriester prodrugs of 2'-deoxy-4'-thioadenosine and its corresponding 9alpha anomer.
    Nucleosides, nucleotides & nucleic acids, 2005, Volume: 24, Issue:5-7

    Topics: Adenosine; Antineoplastic Agents; Antiviral Agents; Chromatography; Chromatography, Thin Layer; Dideoxynucleotides; Drug Design; Guanosine; Humans; Inhibitory Concentration 50; Models, Chemical; Nucleosides; Organophosphonates; Phosphates; Prodrugs; Stereoisomerism; Thionucleosides; Zidovudine

2005
Synthesis and anti-HIV activity of 2'-fluorine modified nucleoside phosphonates: analogs of GS-9148.
    Bioorganic & medicinal chemistry letters, 2008, Feb-01, Volume: 18, Issue:3

    Topics: Anti-HIV Agents; Fluorine; Guanosine; Humans; Molecular Structure; Nucleosides; Organophosphonates; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Zidovudine

2008
Synthesis and anti-HIV activity of GS-9148 (2'-Fd4AP), a novel nucleoside phosphonate HIV reverse transcriptase inhibitor.
    Bioorganic & medicinal chemistry letters, 2008, Feb-01, Volume: 18, Issue:3

    Topics: Anti-HIV Agents; DNA, Mitochondrial; Fluorine; Guanosine; HIV Reverse Transcriptase; Humans; Molecular Structure; Nucleosides; Organophosphonates; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Zidovudine

2008