Page last updated: 2024-08-23

zidovudine and guanine

zidovudine has been researched along with guanine in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (30.00)18.2507
2000's5 (50.00)29.6817
2010's2 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Anderson, KS; Chu, CK; Mathew, JS; Ray, AS; Schinazi, RF; Shi, J1
Holý, A; Merta, A; Stĕtina, R; Votruba, I1
Ahmed, PS; Brennan, TM; Bridges, CG; Casara, P; Hornsperger, JM; Navé, JF; Taylor, DL; Tyms, AS1
Coffman, BL; Green, MD; Iyer, L; King, CD; Ratain, MJ; Roy, SK; Tephly, TR; Whitington, PF1
Bhat, S; Brennan, TP; Chong, CR; Hale, B; Hegarty, R; Jilek, BL; Liu, JO; McMahon, MA; Shen, L; Siliciano, RF; Thio, CL; Wind-Rotolo, M; Xing, S; Zhou, Y1
Fromentin, E; Hernandez-Santiago, BI; Hurwitz, SJ; Obikhod, A; Schinazi, RF1
Hoest, C; Jacobson, S; Rashti, F; Schott, TC; Yao, K1
Asif, G; Fromentin, E; Hurwitz, SJ; Obikhod, A; Schinazi, RF1
Kohli, RM; McMahon, MA; Siliciano, JD; Siliciano, RF1
Adhikary, A; Khanduri, D; Pottiboyina, V; Rice, CT; Sevilla, MD1

Other Studies

10 other study(ies) available for zidovudine and guanine

ArticleYear
2('),3(')-didehydro-2('),3(')-dideoxynucleosides are degraded to furfuryl alcohol under acidic conditions.
    Bioorganic & medicinal chemistry letters, 2004, May-03, Volume: 14, Issue:9

    Topics: Acids; Animals; Cell Line; Dideoxynucleosides; Furans; Humans; Magnetic Resonance Spectroscopy

2004
The effect of purine phosphonomethoxyalkyl derivatives on DNA synthesis in CHO Chinese hamster cells.
    Neoplasma, 1993, Volume: 40, Issue:6

    Topics: Adenine; Animals; Antiviral Agents; CHO Cells; Cricetinae; Cricetulus; Cytarabine; DNA Damage; DNA Replication; Dose-Response Relationship, Drug; Guanine; Organophosphonates; Organophosphorus Compounds; Zidovudine

1993
MDL 74,968, a new acyclonucleotide analog: activity against human immunodeficiency virus in vitro and in the hu-PBL-SCID.beige mouse model of infection.
    Antimicrobial agents and chemotherapy, 1996, Volume: 40, Issue:5

    Topics: Adenine; Animals; Antiviral Agents; Cell Line; Cells, Cultured; Didanosine; DNA, Viral; Guanine; HIV Infections; HIV-1; HIV-2; Humans; Male; Mice; Mice, SCID; Monocytes; Organophosphonates; Spleen; T-Lymphocytes; Zidovudine

1996
Genetic predisposition to the metabolism of irinotecan (CPT-11). Role of uridine diphosphate glucuronosyltransferase isoform 1A1 in the glucuronidation of its active metabolite (SN-38) in human liver microsomes.
    The Journal of clinical investigation, 1998, Feb-15, Volume: 101, Issue:4

    Topics: Animals; Antineoplastic Agents, Phytogenic; Bilirubin; Camptothecin; Causality; Crigler-Najjar Syndrome; Glucuronosyltransferase; Guanine; Humans; Irinotecan; Isoenzymes; Microsomes, Liver; Nitrophenols; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Uridine Diphosphate; Zidovudine

1998
The HBV drug entecavir - effects on HIV-1 replication and resistance.
    The New England journal of medicine, 2007, Jun-21, Volume: 356, Issue:25

    Topics: Adult; Antiviral Agents; CD4 Lymphocyte Count; Drug Resistance, Viral; Guanine; Hepatitis B; Hepatitis B virus; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Male; Middle Aged; Mutation; Phylogeny; Reverse Transcriptase Inhibitors; Reverse Transcription; RNA, Viral; Virus Replication; Zidovudine

2007
Short communication cellular pharmacology of 9-(beta-D-1,3-dioxolan-4-yl) guanine and its lack of drug interactions with zidovudine in primary human lymphocytes.
    Antiviral chemistry & chemotherapy, 2007, Volume: 18, Issue:6

    Topics: Cells, Cultured; Dioxolanes; Dose-Response Relationship, Drug; Drug Interactions; Guanine; Half-Life; HIV; Humans; Lymphocytes; Mutation; Phosphorylation; Prodrugs; Zidovudine

2007
Effect of (r)-9-[4-hydroxy-2-(hydroxymethyl)butyl]guanine (H2G) and AZT-lipid-PFA on human herpesvirus-6B infected cells.
    Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2009, Volume: 46, Issue:1

    Topics: Antiviral Agents; Cell Line; Cell Survival; Cells, Cultured; Guanine; Hepatocytes; Herpesvirus 6, Human; Humans; Leukocytes, Mononuclear; Microbial Sensitivity Tests; Transcription, Genetic; Virus Replication; Zidovudine

2009
Simultaneous quantification of 9-(beta-D-1,3-dioxolan-4-yl)guanine, Amdoxovir and Zidovudine in human plasma by liquid chromatography-tandem mass spectrometric assay.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2009, Nov-01, Volume: 877, Issue:29

    Topics: Antiviral Agents; Chromatography, Liquid; Dioxolanes; Guanine; Humans; Purine Nucleosides; Reproducibility of Results; Tandem Mass Spectrometry; Zidovudine

2009
Sensitivity of V75I HIV-1 reverse transcriptase mutant selected in vitro by acyclovir to anti-HIV drugs.
    AIDS (London, England), 2010, Jan-16, Volume: 24, Issue:2

    Topics: Acyclovir; Anti-HIV Agents; Antiviral Agents; Drug Resistance, Viral; Guanine; Herpes Genitalis; Herpesvirus 2, Human; HIV Reverse Transcriptase; HIV-1; Humans; Mutation; Viral Load; Virus Replication; Zidovudine

2010
Formation of aminyl radicals on electron attachment to AZT: abstraction from the sugar phosphate backbone versus one-electron oxidation of guanine.
    The journal of physical chemistry. B, 2010, Jul-22, Volume: 114, Issue:28

    Topics: Anti-HIV Agents; Electron Spin Resonance Spectroscopy; Electrons; Free Radicals; Guanine; Models, Theoretical; Oxidation-Reduction; Sugar Phosphates; Thymidine; Thymine; Zidovudine

2010