Page last updated: 2024-08-23

zidovudine and glutamine

zidovudine has been researched along with glutamine in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (18.18)18.2507
2000's6 (54.55)29.6817
2010's2 (18.18)24.3611
2020's1 (9.09)2.80

Authors

AuthorsStudies
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
McGregor, WG; Roberts, J1
Caliendo, AM; Chow, YK; Cooley, TP; D'Aquila, RT; Devore, KM; Eron, JJ; Hirsch, MS; Kaplan, JC; Liebman, HA; Videler, J1
Adman, ET; Isaacs, SJ; Kim, B; Tran, NH; Weiss, KK1
Cotter, RL; Curthoys, NP; Erichsen, D; Herek, S; Lopez, AL; Zhao, J; Zheng, J1
Guo, D; Jamburuthugoda, VK; Kim, B; Wedekind, JE1
Arnold, E; Boyer, PL; Clark, PK; Hughes, SH; Sarafianos, SG1
Brehm, JH; Mellors, JW; Sluis-Cremer, N1
Fortuin, R; Sitole, L; Tugizimana, F1

Reviews

1 review(s) available for zidovudine and glutamine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

10 other study(ies) available for zidovudine and glutamine

ArticleYear
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Inhibition of mouse retroviral disease by bioactive glutaminase-asparaginase.
    The Journal of general virology, 1991, Volume: 72 ( Pt 2)

    Topics: Amidohydrolases; Animals; Blotting, Western; Cell Line; Glutamine; Leukemia, Experimental; Mice; Organ Size; Protein Biosynthesis; Rauscher Virus; RNA-Directed DNA Polymerase; Spleen; Virus Replication; Zidovudine

1991
pol mutations conferring zidovudine and didanosine resistance with different effects in vitro yield multiply resistant human immunodeficiency virus type 1 isolates in vivo.
    Antimicrobial agents and chemotherapy, 1993, Volume: 37, Issue:7

    Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Complex; Didanosine; Drug Resistance, Microbial; Genes, pol; Glutamine; HIV Reverse Transcriptase; HIV-1; Humans; Leucine; Microbial Sensitivity Tests; Mutation; Phenotype; Polymerase Chain Reaction; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Tyrosine; Valine; Zidovudine

1993
Molecular architecture of the mutagenic active site of human immunodeficiency virus type 1 reverse transcriptase: roles of the beta 8-alpha E loop in fidelity, processivity, and substrate interactions.
    Biochemistry, 2000, Sep-05, Volume: 39, Issue:35

    Topics: Amino Acid Substitution; Anti-HIV Agents; Base Pair Mismatch; Binding Sites; Dideoxynucleotides; DNA Mutational Analysis; DNA Primers; Glutamine; Glycine; HIV Reverse Transcriptase; Humans; Lac Operon; Lysine; Mutagenesis, Site-Directed; Protein Processing, Post-Translational; Protein Structure, Secondary; RNA; Substrate Specificity; Templates, Genetic; Thymine Nucleotides; Tryptophan; Zidovudine

2000
Mitochondrial glutaminase enhances extracellular glutamate production in HIV-1-infected macrophages: linkage to HIV-1 associated dementia.
    Journal of neurochemistry, 2004, Volume: 88, Issue:1

    Topics: AIDS Dementia Complex; Anti-HIV Agents; Cell Survival; Cells, Cultured; Chromatography, High Pressure Liquid; Culture Media, Conditioned; Dose-Response Relationship, Drug; Enzyme Inhibitors; Extracellular Space; Glutamic Acid; Glutaminase; Glutamine; HIV Infections; HIV-1; Humans; Macrophages; Mitochondria; Monocytes; RNA, Messenger; Zidovudine

2004
Kinetic evidence for interaction of human immunodeficiency virus type 1 reverse transcriptase with the 3'-OH of the incoming dTTP substrate.
    Biochemistry, 2005, Aug-09, Volume: 44, Issue:31

    Topics: Acyclovir; Amino Acid Substitution; Asparagine; Dideoxynucleotides; Glutamine; HIV Reverse Transcriptase; Hydroxyl Radical; Isoleucine; Kinetics; Models, Molecular; Protein Binding; Substrate Specificity; Thymine Nucleotides; Valine; Zidovudine

2005
Why do HIV-1 and HIV-2 use different pathways to develop AZT resistance?
    PLoS pathogens, 2006, Volume: 2, Issue:2

    Topics: Amino Acid Sequence; Drug Resistance, Viral; Glutamine; HIV-1; HIV-2; Methionine; Molecular Sequence Data; Mutation; Protein Structure, Tertiary; RNA-Directed DNA Polymerase; Zidovudine

2006
Mechanism by which a glutamine to leucine substitution at residue 509 in the ribonuclease H domain of HIV-1 reverse transcriptase confers zidovudine resistance.
    Biochemistry, 2008, Dec-30, Volume: 47, Issue:52

    Topics: Amino Acid Substitution; Binding, Competitive; Drug Resistance, Viral; Glutamine; HIV Reverse Transcriptase; Kinetics; Leucine; Reverse Transcriptase Inhibitors; Ribonuclease H; Zidovudine

2008
Metabolic profiling of HIV infected individuals on an AZT-based antiretroviral treatment regimen reveals persistent oxidative stress.
    Journal of pharmaceutical and biomedical analysis, 2022, Oct-25, Volume: 220

    Topics: Anti-HIV Agents; Anti-Retroviral Agents; Arginine; Biomarkers; Disease Progression; Glucose; Glutamates; Glutamine; Glutathione; HIV Infections; Humans; Oxidative Stress; Reproducibility of Results; Zidovudine

2022