Page last updated: 2024-08-23

zidovudine and foscarnet

zidovudine has been researched along with foscarnet in 98 studies

Research

Studies (98)

Timeframe	Studies, this research(%)	All Research%
pre-1990	21 (21.43)	18.7374
1990's	48 (48.98)	18.2507
2000's	21 (21.43)	29.6817
2010's	8 (8.16)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Corbett, TH; Court, BA; Kessel, D; Phadtare, S; Renis, HE; Zimlicka, J	1
De Clercq, E	1
Fu, H; Hostetler, KY; Mellors, J; Pai, N; Richman, DD; Rosowsky, A	1
Cha, SH; Endou, H; Kanai, Y; Kimura, M; Sekine, T; Tsuda, M; Wada, S	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Chen, JJ; Cheng, P; Jiang, ZY; Wang, Q; Wang, RR; Zhang, XM; Zheng, YT; Zhou, J	1
Lombardo, F; Obach, RS; Waters, NJ	1
Chou, KC; González-Díaz, H; Martinez de la Vega, O; Prado-Prado, FJ; Ubeira, FM; Uriarte, E	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Campillo, NE; Guerra, A; Páez, JA	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Endo, T; Higuchi, H; Kaji, A; Kaji, H; Kato, A; Matsumoto, H; Mochida, S; Ogata, T	1
Skolnik, PR	1
Connolly, S; Malin, A; Manji, H	1
Causey, DM; Davis, RB; Grieco, MH; Hooton, TM; Jacobson, MA; McKinley, GF; Parenti, DM; Reddy, MM; van der Horst, CM	1
Morris, DJ	2
Cheng, YC; Dutschman, GE; Im, GJ; Mellors, JW; Tramontano, E; Winkler, SR	1
Cheng, YC; Tramontano, E	1
Burrell, CJ; Kuiper, LJ; Li, P; Stephenson, AJ	1
Aweeka, FT; Gambertoglio, JG; Jacobson, MA; Raasch, R; van der Horst, C	1
Seigneurin, JM	1
Cox, SW; Wahren, B	1
Anderson, S; Beck, EJ; Coker, R; Coleman, D; Harris, JR; Main, J; Migdal, C; Peters, BS; Pinching, AJ	1
Ayisi, NK; Gupta, SV; Qualtiere, LF	1
Kemp, SD; Larder, BA; Lowe, DM; Parmar, V	1
Quan, K; Tao, P; Zhang, X	1
Cox, S; Harmenberg, J; Koshida, R; Wahren, B	1
Armstrong, D; Chou, TC; Gold, JW; Kong, XB; Polsky, B; Ruprecht, RM; Watanabe, KA; Zeidler, JM; Zhu, QY	1
Cersosimo, RJ; Matthews, SJ; Spivack, ML	1
Causey, DM; Dehlinger, M; Hafner, R; Jacobsen, MA; Mills, J; van der Horst, C	1
Aubertin, P; Barrier, JH; Boibieux, A; Lortholary, A; Peyramond, D; Raffi, F	1
Balzarini, J; Bron, D; De Clercq, E; Delforge, A; Lagneaux, L; Snoeck, R; Stryckmans, P; Van der Auwera, P	1
Hirsch, MS; Schooley, RT; Vogt, M	1
Pomerantz, RJ; Schooley, RT	1
Bryson, YJ	1
Darby, G; Larder, BA; Richman, DD	1
Mitchell, WM; Montefiori, DC; Robinson, WE	1
Kemp, SD; Larder, BA; Purifoy, DJ	1
Kurth, R; Löwer, J; Oberg, B; Vrang, L	1
Gilljam, G; Harmenberg, J; Koshida, R; Oberg, B; Vrang, L; Wahren, B	1
Crowe, SM; Elbeik, T; Kirihara, J; McGrath, MS; Mills, J	1
Cox, S; Gilljam, G; Harmenberg, J; Koshida, R; Wahren, B	1
Jacobson, MA; O'Donnell, JJ	1
Girard, B; Katlama, C; Lehoang, P; Lernestedt, JO; Marcel, P; Matheron, S; Morer, I; Robinet, M; Rozenbaum, W; Zazoun, L	1
Eriksson, BF; Schinazi, RF	1
Kaplan, JC; Sandström, EG	1
Broder, S; Yarchoan, R	1
Wyngaarden, JB	1
Richman, DD	1
Collins, P; Evans, R; Hawkins, DA; Lawrence, A; Oliver, N; Shanson, DC; Youle, MM	1
Sandström, E	1
Weber, J	1
Cheng, YC; Gonzalez, CJ; Im, GJ; Tramontano, E	1
Birch, C; Hoy, J; McGavin, K; Tachedjian, G	1
Caliendo, AM; Hirsch, MS	1
Blay, RA; Buck, SM; Epstein, JS; Geyer, S; Mayner, RE; Pollock, L; Selvam, MP	1
Fleckenstein, B; Stamminger, T	1
Gobert, JM; North, TW; Remington, KM; Zhu, YQ	1
Brun-Vezinet, F; Pépin, JM; Simon, F	1
Baird, BF; Davey, RT; deSmet, MD; Falloon, J; Kovacs, JA; Masur, H; Mellow, S; Nussenblatt, RB; Palestine, AG; Polis, MA	1
Blackburn, EH; Strahl, C	1
Anderson, KP; Azad, RF; Brown-Driver, V; Buckheit, RW	1
Detels, RR; Hoover, DR; Peng, Y; Phair, JP; Rinaldo, CR; Saah, A; Semba, R	1
Cox, S; Harmenberg, J; Palmer, S	1
Bazmi, H; Birch, C; Mellors, J; Mills, J; Tachedjian, G	1
Beauchamp, D; Bergeron, MG; Désormeaux, A; Gourde, P; Omar, RF; Tremblay, M	1
Brisson, E; Guettari, N; Klatzmann, D; Loubière, L	1
Alaeus, A; Albert, J; Cox, S; Palmer, S	1
Andreula, CF; Angarano, G; Appice, A; Di Stefano, M; Fiore, JR; Monno, L; Pastore, G; Perulli, LM; Zimatore, GB	1
French, M; Mills, J; Tachedjian, G	1
Arion, D; Borkow, G; Kaushik, N; McCormick, S; Parniak, MA	1
Aubertin, AM; de Monte, M; Faraj, A; Gosselin, G; Imbach, JL; Meier, C; Périgaud, C; Sommadossi, JP	1
Bazmi, HZ; La Colla, P; Mellors, JW; Piras, G; Putzolu, M; Tramontano, E	1
Bareta, J; Hidalgo, J; Rhee, W; Steidl, S; Wutoh, AK	1
Arion, D; Parniak, MA; Sluis-Cremer, N	1
Aldern, KA; Beadle, JR; Chou, TC; Hammond, JL; Hostetler, KY; Hostetler, SE; Kini, GD; Mellors, JW; Richman, DD	1
Boretto, J; Canard, B; Capony, JP; Lazaro, JB; Selmi, B	1
Aldern, KA; Bazmi, HZ; Beadle, JR; Hammond, JL; Hostetler, KY; Hostetler, SE; Kini, GD; Koontz, DL; Mellors, JW; Richman, DD	1
Gérard, M; Hainaut, M; Levy, J; Mascart, F; Peltier, CA; Souayah, H; Zissis, G	1
Bazmi, HZ; Chopra, RR; Matsuura, SE; Mellors, JW; Meyer, PR; Pendarvis, E; Scott, WA; Zonarich, D	1
Goldschmidt, V; Marquet, R	1
Bocharov, EV; Fedyuk, NV; Ivanov, AV; Jasko, MV; Khandazhinskaya, AL; Kukhanova, MK; Mitkevich, VA; Pokrovsky, AG; Pronyaeva, TR; Shirokova, EA; Skoblov, YS; Yanvarev, DV	1
Feuston, B; Getty, K; Hazuda, DJ; Krueger, J; Lewis, D; Miller, MD; Munshi, V; Parniak, MA; Shaw-Reid, CA	1
Anderson, DJ; Preston, BD; Smith, RA	1
Ansó, E; Cruchaga, C; Martínez-Irujo, JJ; Rouzaut, A	1
Clavel, F; Dam, E; Gerstoft, J; Joergensen, LB; Laursen, AL; Mathiesen, S; Roge, B	1
Kisic, M; Martínez, MA; Martinez-Picado, J; Mendieta, J; Menéndez-Arias, L; Parera, M; Puertas, MC	1
Bélec, L; Charpentier, C; Karmochkine, M; Laureillard, D; Piketty, C; Si-Mohamed, A; Sodqi, M; Weiss, L	1
Hamprecht, K; Schott, H; Schott, S; Schott, TC; Schwendener, RA	1
Tan, DH; Walmsley, SL	1
Arastéh, K; Dieckmann, S; Drauz, D; Grueneisen, A; Koch, A; Marretta, L; Masuhr, A; Mueller, M; Stocker, H; Weiss, R; Wong, V	1
Agut, H; Caumes, E; Challine, D; Deback, C; Lascaux, AS; Lévy, Y; Melica, G	1
Auge-Courtoi, C; Charpentier, C; Delory, T; Descamps, D; Matheron, S; Michard, F; Papot, E; Peytavin, G; Rioux, C; Yazdanpanah, Y	1

Reviews

15 review(s) available for zidovudine and foscarnet

Article	Year
Chemotherapeutic approaches to the treatment of the acquired immune deficiency syndrome (AIDS). Journal of medicinal chemistry, 1986, Volume: 29, Issue:9 Topics: Acquired Immunodeficiency Syndrome; Adsorption; Antibodies, Viral; Antigens, Viral; Aurintricarboxylic Acid; Deltaretrovirus; Deoxycytidine; Foscarnet; Genes, Viral; Glycoproteins; Humans; Interferons; Male; Phosphonoacetic Acid; Retroviridae Infections; Reverse Transcriptase Inhibitors; Ribavirin; RNA, Viral; Suramin; Thymidine; Transcription, Genetic; Viral Proteins; Virus Replication; Zalcitabine; Zidovudine	1986
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Zidovudine and other reverse transcriptase inhibitors in the management of human immunodeficiency virus-related disease. Pharmacotherapy, 1991, Volume: 11, Issue:6 Topics: Acquired Immunodeficiency Syndrome; Adult; Antiviral Agents; Child; Didanosine; Female; Foscarnet; HIV Infections; Humans; Phosphonoacetic Acid; Pregnancy; Reverse Transcriptase Inhibitors; Zalcitabine; Zidovudine	1991
Therapy of human immunodeficiency virus infections. Clinics in laboratory medicine, 1987, Volume: 7, Issue:4 Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Foscarnet; Humans; Immunotherapy; Interferons; Oligodeoxyribonucleotides; Phosphonoacetic Acid; Ribavirin; Suramin; Thymidine; Zidovudine	1987
Promising new antiviral drugs. Journal of the American Academy of Dermatology, 1988, Volume: 18, Issue:1 Pt 2 Topics: Acyclovir; Animals; Antiviral Agents; Bromodeoxyuridine; Cytomegalovirus Infections; Foscarnet; Ganciclovir; Herpes Simplex; Herpes Zoster; Humans; Interferons; Phosphonoacetic Acid; Ribavirin; Thymidine; Zidovudine	1988
Cotton-wool spots and cytomegalovirus retinitis in AIDS. International ophthalmology clinics, 1989,Summer, Volume: 29, Issue:2 Topics: Acquired Immunodeficiency Syndrome; Acyclovir; Cytomegalovirus Infections; Diabetic Retinopathy; Diagnosis, Differential; Foscarnet; Ganciclovir; Humans; Phosphonoacetic Acid; Pneumonia, Pneumocystis; Prognosis; Retinal Diseases; Retinitis; Zidovudine	1989
Antiviral therapy in AIDS. Clinical pharmacological properties and therapeutic experience to date. Drugs, 1987, Volume: 34, Issue:3 Topics: Acquired Immunodeficiency Syndrome; Antimony; Antiviral Agents; Forecasting; Foscarnet; Immunotherapy; Phosphonoacetic Acid; Rifabutin; Rifamycins; Suramin; Thymidine; Tungsten; Tungsten Compounds; Zidovudine	1987
Progress in the development of antiviral therapy for HTLV-III-associated diseases. Important advances in oncology, 1987 Topics: Acquired Immunodeficiency Syndrome; Antimony; Antiviral Agents; Foscarnet; HIV; Humans; Phosphonoacetic Acid; Ribavirin; Rifabutin; Rifamycins; Suramin; Thymidine; Tungsten; Tungsten Compounds; Zidovudine	1987
The treatment of HIV infection. AIDS (London, England), 1988, Volume: 2 Suppl 1 Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Clinical Trials as Topic; Dideoxynucleosides; Drug Evaluation; Foscarnet; Humans; Opportunistic Infections; Phosphonoacetic Acid; Zalcitabine; Zidovudine	1988
Antiviral drugs for AIDS. Current status and future prospects. Drugs, 1986, Volume: 31, Issue:6 Topics: Acquired Immunodeficiency Syndrome; Antimony; Antiviral Agents; Foscarnet; Humans; Interferon Type I; Phosphonoacetic Acid; Ribavirin; Suramin; Thymidine; Tungsten; Tungsten Compounds; Zidovudine	1986
Combination therapy for infection due to human immunodeficiency virus type 1. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1994, Volume: 18, Issue:4 Topics: Acyclovir; Antiviral Agents; CD4 Antigens; Clinical Trials as Topic; Combined Modality Therapy; Didanosine; Drug Therapy, Combination; Foscarnet; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; In Vitro Techniques; Interferon alpha-2; Interferon-alpha; Recombinant Proteins; Reverse Transcriptase Inhibitors; Zalcitabine; Zidovudine	1994
Adverse effects and drug interactions of clinical importance with antiviral drugs. Drug safety, 1994, Volume: 10, Issue:4 Topics: Acyclovir; AIDS-Related Opportunistic Infections; Amantadine; Antiviral Agents; Didanosine; Drug Interactions; Foscarnet; Ganciclovir; Humans; Interferon-alpha; Ribavirin; Rimantadine; Vidarabine; Zalcitabine; Zidovudine	1994
[Is resistance of human immunodeficiency viruses (HIV) to nucleoside analogs an indication for their combined use?]. Pathologie-biologie, 1993, Volume: 41, Issue:8 Pt 2 Topics: Acyclovir; Didanosine; Drug Synergism; Drug Therapy, Combination; Female; Foscarnet; HIV-1; Humans; In Vitro Techniques; Male; Ribavirin; Zalcitabine; Zidovudine	1993
Increased survival of a cohort of patients with acquired immunodeficiency syndrome and cytomegalovirus retinitis who received sodium phosphonoformate (foscarnet). The American journal of medicine, 1993, Volume: 94, Issue:2 Topics: Acquired Immunodeficiency Syndrome; Cohort Studies; Cytomegalovirus Infections; Didanosine; Drug Tolerance; Follow-Up Studies; Foscarnet; Ganciclovir; Humans; Infusions, Intravenous; Injections, Intravenous; Retinitis; Survival Rate; Time Factors; Zidovudine	1993
Primer unblocking by HIV-1 reverse transcriptase and resistance to nucleoside RT inhibitors (NRTIs). The international journal of biochemistry & cell biology, 2004, Volume: 36, Issue:9 Topics: Adenosine Triphosphate; DNA Primers; Drug Resistance, Multiple, Viral; Foscarnet; HIV; HIV Reverse Transcriptase; Humans; Point Mutation; Reverse Transcriptase Inhibitors; Thymidine; Zidovudine	2004

Trials

6 trial(s) available for zidovudine and foscarnet

Article	Year
Effect of foscarnet therapy on human immunodeficiency virus p24 antigen levels in AIDS patients with cytomegalovirus retinitis. The Journal of infectious diseases, 1992, Volume: 166, Issue:3 Topics: Acquired Immunodeficiency Syndrome; Adult; Cytomegalovirus Infections; Dose-Response Relationship, Drug; Drug Evaluation; Foscarnet; HIV Core Protein p24; Humans; Middle Aged; Phosphonoacetic Acid; Retinitis; Zidovudine	1992
Mortality in patients with the acquired immunodeficiency syndrome treated with either foscarnet or ganciclovir for cytomegalovirus retinitis. The New England journal of medicine, 1992, 01-23, Volume: 326, Issue:4 Topics: Acquired Immunodeficiency Syndrome; Adult; Antiviral Agents; CD4-Positive T-Lymphocytes; Cytomegalovirus Infections; Drug Therapy, Combination; Drug Tolerance; Foscarnet; Ganciclovir; Humans; Leukocyte Count; Phosphonoacetic Acid; Random Allocation; Retinitis; Zidovudine	1992
[Chemotherapy and immunoprophylaxis of HIV infection]. Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis, 1986, Nov-25, Volume: 75, Issue:48 Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Clinical Trials as Topic; Foscarnet; HIV; Humans; Phosphonoacetic Acid; Reverse Transcriptase Inhibitors; Ribavirin; Suramin; Thymidine; Viral Vaccines; Virus Replication; Zidovudine	1986
From the National Institutes of Health. Progress in AIDS research. JAMA, 1988, Dec-16, Volume: 260, Issue:23 Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Clinical Trials as Topic; Cytomegalovirus Infections; Drug Therapy, Combination; Foscarnet; Humans; Interferon Type I; Phosphonoacetic Acid; Recombinant Proteins; Research; Vaccines; Zidovudine	1988
The treatment of HIV infection. AIDS (London, England), 1988, Volume: 2 Suppl 1 Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Clinical Trials as Topic; Dideoxynucleosides; Drug Evaluation; Foscarnet; Humans; Opportunistic Infections; Phosphonoacetic Acid; Zalcitabine; Zidovudine	1988
Increased survival of a cohort of patients with acquired immunodeficiency syndrome and cytomegalovirus retinitis who received sodium phosphonoformate (foscarnet). The American journal of medicine, 1993, Volume: 94, Issue:2 Topics: Acquired Immunodeficiency Syndrome; Cohort Studies; Cytomegalovirus Infections; Didanosine; Drug Tolerance; Follow-Up Studies; Foscarnet; Ganciclovir; Humans; Infusions, Intravenous; Injections, Intravenous; Retinitis; Survival Rate; Time Factors; Zidovudine	1993

Other Studies

79 other study(ies) available for zidovudine and foscarnet

Article	Year
Unsaturated and carbocyclic nucleoside analogues: synthesis, antitumor, and antiviral activity. Journal of medicinal chemistry, 1991, Volume: 34, Issue:1 Topics: Adenosine Deaminase; Animals; Antimetabolites, Antineoplastic; Antiviral Agents; Cell Line; Cell Survival; Drug Screening Assays, Antitumor; Friend murine leukemia virus; HIV-1; HIV-2; Humans; Indicators and Reagents; Leukemia L1210; Mice; Molecular Structure; Nucleosides; Rauscher Virus; Structure-Activity Relationship	1991
Synthesis and in vitro activity of long-chain 5'-O-[(alkoxycarbonyl)phosphinyl]-3'-azido-3'-deoxythymidines against wild-type and AZT- and foscarnet-resistant strains of HIV-1. Journal of medicinal chemistry, 1997, Aug-01, Volume: 40, Issue:16 Topics: Anti-HIV Agents; CD4-Positive T-Lymphocytes; Cell Line; Drug Combinations; Drug Resistance, Microbial; Foscarnet; HIV-1; Humans; Magnetic Resonance Spectroscopy; Models, Chemical; Mutagenesis, Site-Directed; Prodrugs; Virus Replication; Zidovudine	1997
Rat multispecific organic anion transporter 1 (rOAT1) transports zidovudine, acyclovir, and other antiviral nucleoside analogs. The Journal of pharmacology and experimental therapeutics, 2000, Volume: 294, Issue:3 Topics: Acyclovir; Animals; Anion Transport Proteins; Antiviral Agents; Carrier Proteins; Didanosine; In Vitro Techniques; Lamivudine; Oocytes; Rats; Stavudine; Transfection; Trifluridine; Xenopus laevis; Zalcitabine; Zidovudine	2000
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Synthesis and biological evaluation of N-acetyl-beta-aryl-1,2-didehydroethylamines as new HIV-1 RT inhibitors in vitro. Bioorganic & medicinal chemistry letters, 2007, Aug-15, Volume: 17, Issue:16 Topics: Ethylamines; HIV Reverse Transcriptase; HIV-1; Molecular Structure; Reverse Transcriptase Inhibitors; Structure-Activity Relationship	2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Unified QSAR approach to antimicrobials. 4. Multi-target QSAR modeling and comparative multi-distance study of the giant components of antiviral drug-drug complex networks. Bioorganic & medicinal chemistry, 2009, Jan-15, Volume: 17, Issue:2 Topics: Anti-Infective Agents; Antiviral Agents; Artificial Intelligence; Computer Simulation; Drug Evaluation, Preclinical; Molecular Structure; Quantitative Structure-Activity Relationship	2009
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Neural computational prediction of oral drug absorption based on CODES 2D descriptors. European journal of medicinal chemistry, 2010, Volume: 45, Issue:3 Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
HIV-1 reverse transcriptase inhibitor from Phyllanthus niruri. AIDS research and human retroviruses, 1992, Volume: 8, Issue:11 Topics: Antigens, Viral; Benzopyrans; Binding, Competitive; Cell Fusion; Chromatography; DNA-Directed DNA Polymerase; Dose-Response Relationship, Drug; Ellagic Acid; Foscarnet; Gallic Acid; Glucose; HIV Core Protein p24; HIV Reverse Transcriptase; HIV-1; Plant Extracts; Plants; Reverse Transcriptase Inhibitors; Zidovudine	1992
Treatment of CMV retinitis. The New England journal of medicine, 1992, Jun-18, Volume: 326, Issue:25 Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Cytomegalovirus Infections; Drug Therapy, Combination; Foscarnet; Ganciclovir; Humans; Phosphonoacetic Acid; Retinitis; Zidovudine	1992
CMV polyradiculopathy in AIDS--suggestions for new strategies in treatment. Genitourinary medicine, 1992, Volume: 68, Issue:3 Topics: Acquired Immunodeficiency Syndrome; Adult; Cytomegalovirus Infections; Foscarnet; Humans; Male; Nervous System Diseases; Phosphonoacetic Acid; Zidovudine	1992
Treatment of CMV retinitis. Lancet (London, England), 1992, Jan-25, Volume: 339, Issue:8787 Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Cytomegalovirus Infections; Eye Infections, Viral; Foscarnet; Ganciclovir; Humans; Phosphonoacetic Acid; Retinitis; Zidovudine	1992
In vitro selection and molecular characterization of human immunodeficiency virus-1 resistant to non-nucleoside inhibitors of reverse transcriptase. Molecular pharmacology, 1992, Volume: 41, Issue:3 Topics: Antiviral Agents; Base Sequence; Benzodiazepines; CD4-Positive T-Lymphocytes; Cloning, Molecular; Drug Resistance, Microbial; Foscarnet; Gene Expression; HeLa Cells; HIV-1; Humans; Imidazoles; Molecular Sequence Data; Nevirapine; Phosphonoacetic Acid; Polymerase Chain Reaction; Pyridines; Recombinant Proteins; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Zidovudine	1992
HIV-1 reverse transcriptase inhibition by a dipyridodiazepinone derivative: BI-RG-587. Biochemical pharmacology, 1992, Mar-17, Volume: 43, Issue:6 Topics: Antiviral Agents; Foscarnet; HIV-1; Kinetics; Nevirapine; Phosphonoacetic Acid; Pyridines; Reverse Transcriptase Inhibitors; Templates, Genetic; Zidovudine	1992
De novo reverse transcription is a crucial event in cell-to-cell transmission of human immunodeficiency virus. The Journal of general virology, 1992, Volume: 73 ( Pt 4) Topics: Antiviral Agents; DNA, Viral; Foscarnet; HIV Reverse Transcriptase; HIV-1; Humans; Middle Aged; Phosphonoacetic Acid; RNA-Directed DNA Polymerase; Virus Replication; Zidovudine	1992
Pharmacokinetics of concomitantly administered foscarnet and zidovudine for treatment of human immunodeficiency virus infection (AIDS Clinical Trials Group protocol 053). Antimicrobial agents and chemotherapy, 1992, Volume: 36, Issue:8 Topics: Acquired Immunodeficiency Syndrome; Adult; Antiviral Agents; Chromatography, High Pressure Liquid; Drug Interactions; Foscarnet; HIV Core Protein p24; Humans; Male; Middle Aged; Zidovudine	1992
[Resistance of viruses to antiviral agents]. Presse medicale (Paris, France : 1983), 1992, Mar-28, Volume: 21, Issue:12 Topics: Acyclovir; Antiviral Agents; Drug Resistance; Foscarnet; Humans; Immunocompromised Host; Phosphonoacetic Acid; Rimantadine; Virus Diseases; Zidovudine	1992
Treatment of CMV retinitis. The New England journal of medicine, 1992, Jun-18, Volume: 326, Issue:25 Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Drug Synergism; Drug Therapy, Combination; Foscarnet; Ganciclovir; Humans; Phosphonoacetic Acid; Zidovudine	1992
Cytomegalovirus infection in AIDS. Patterns of disease, response to therapy and trends in survival. The Journal of infection, 1991, Volume: 23, Issue:2 Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Colitis; Cytomegalovirus Infections; Female; Foscarnet; Ganciclovir; Humans; London; Male; Neutropenia; Opportunistic Infections; Phosphonoacetic Acid; Prevalence; Recurrence; Retinitis; Retrospective Studies; Survival Rate; Thrombocytopenia; Zidovudine	1991
Modified tetrazolium-based colorimetric method for determining the activities of anti-HIV compounds. Journal of virological methods, 1991, Volume: 33, Issue:3 Topics: Antiviral Agents; Cell Line; Colorimetry; Didanosine; Foscarnet; HIV-1; Humans; Phosphonoacetic Acid; Tetrazolium Salts; Thymidine; Zalcitabine; Zidovudine	1991
Mutational analysis of two conserved sequence motifs in HIV-1 reverse transcriptase. FEBS letters, 1991, May-06, Volume: 282, Issue:2 Topics: Amino Acid Sequence; Dideoxynucleotides; DNA Mutational Analysis; Foscarnet; HIV-1; In Vitro Techniques; Kinetics; Molecular Sequence Data; Phosphonoacetic Acid; Recombinant Proteins; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Structure-Activity Relationship; Thymine Nucleotides; Zidovudine	1991
The characterization of EIAV reverse transcriptase and its inhibition by 5'-triphosphates of 2'-deoxyuridine analogs, PFA and PAA. Proceedings of the Chinese Academy of Medical Sciences and the Peking Union Medical College = Chung-kuo i hsueh k'o hsueh yuan, Chung-kuo hsieh ho i k'o ta hsueh hsueh pao, 1990, Volume: 5, Issue:3 Topics: Antiviral Agents; Dideoxynucleotides; Foscarnet; HIV; Infectious Anemia Virus, Equine; Phosphonoacetic Acid; RNA-Directed DNA Polymerase; Thymine Nucleotides; Zidovudine	1990
Synergistic combinations and peptides in the inhibition of human immunodeficiency virus. Advances in enzyme regulation, 1991, Volume: 31 Topics: Alpha-Globulins; Amino Acid Sequence; Antiviral Agents; Cell Line; Dideoxynucleosides; Drug Synergism; Foscarnet; HIV; Humans; Molecular Sequence Data; Oligopeptides; Phosphonoacetic Acid; Proteins; Reverse Transcriptase Inhibitors; Serine Proteinase Inhibitors; Virus Replication; Zidovudine	1991
Synergistic inhibition of human immunodeficiency virus type 1 replication in vitro by two-drug and three-drug combinations of 3'-azido-3'-deoxythymidine, phosphonoformate, and 2',3'-dideoxythymidine. Antimicrobial agents and chemotherapy, 1991, Volume: 35, Issue:10 Topics: Antiviral Agents; Cell Line; Cell Survival; Cell-Free System; Dideoxynucleosides; Drug Synergism; Enzyme-Linked Immunosorbent Assay; Foscarnet; HIV-1; Humans; Phosphonoacetic Acid; Reverse Transcriptase Inhibitors; Virus Replication; Zidovudine	1991
In vivo additive antiretroviral effect of combined zidovudine and foscarnet therapy for human immunodeficiency virus infection (ACTG Protocol 053). The Journal of infectious diseases, 1991, Volume: 163, Issue:6 Topics: Administration, Oral; Antiviral Agents; Drug Therapy, Combination; Follow-Up Studies; Foscarnet; Gene Products, gag; HIV Antigens; HIV Core Protein p24; HIV Infections; Humans; Infusions, Intravenous; Phosphonoacetic Acid; Viral Core Proteins; Zidovudine	1991
HIV-associated haemophagocytic syndrome. Lancet (London, England), 1990, Nov-03, Volume: 336, Issue:8723 Topics: Acquired Immunodeficiency Syndrome; Adult; Anti-Bacterial Agents; Antiviral Agents; Drug Therapy, Combination; Foscarnet; Histiocytosis, Non-Langerhans-Cell; Humans; Male; Phosphonoacetic Acid; Zidovudine	1990
Inhibitory effects of potent inhibitors of human immunodeficiency virus and cytomegalovirus on the growth of human granulocyte-macrophage progenitor cells in vitro. European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 1990, Volume: 9, Issue:8 Topics: Adenine; Adult; Antiviral Agents; Bone Marrow; Bone Marrow Cells; Cells, Cultured; Cidofovir; Cytomegalovirus; Cytosine; Foscarnet; Ganciclovir; Granulocytes; Hematopoietic Stem Cells; HIV; Humans; Macrophages; Organophosphonates; Organophosphorus Compounds; Phosphonoacetic Acid; Zidovudine	1990
HIV with reduced sensitivity to zidovudine (AZT) isolated during prolonged therapy. Science (New York, N.Y.), 1989, Mar-31, Volume: 243, Issue:4899 Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Complex; Dideoxynucleosides; Drug Resistance; Foscarnet; HeLa Cells; HIV; HIV Core Protein p24; Humans; Microbial Sensitivity Tests; Phosphonoacetic Acid; Retroviridae Proteins; Reverse Transcriptase Inhibitors; Viral Plaque Assay; Virus Replication; Zalcitabine; Zidovudine	1989
In vitro evaluation of mismatched double-stranded RNA (ampligen) for combination therapy in the treatment of acquired immunodeficiency syndrome. AIDS research and human retroviruses, 1989, Volume: 5, Issue:2 Topics: Acquired Immunodeficiency Syndrome; Alkaloids; Amphotericin B; Antiviral Agents; Drug Therapy, Combination; Foscarnet; HIV; Humans; In Vitro Techniques; Indolizines; Interferon beta-1a; Interferon beta-1b; Interferon Type I; Interferon-beta; Interferon-gamma; Interferons; Microbial Sensitivity Tests; Phosphonoacetic Acid; Recombinant Proteins; Ribavirin; RNA, Double-Stranded; Zidovudine	1989
Infectious potential of human immunodeficiency virus type 1 reverse transcriptase mutants with altered inhibitor sensitivity. Proceedings of the National Academy of Sciences of the United States of America, 1989, Volume: 86, Issue:13 Topics: Amino Acid Sequence; Antiviral Agents; Cell Line; Cloning, Molecular; Escherichia coli; Foscarnet; Genes; Genes, Viral; HIV-1; Humans; Molecular Sequence Data; Mutation; Phosphonoacetic Acid; Recombinant Proteins; RNA-Directed DNA Polymerase; Transfection; Zidovudine	1989
Reverse transcriptases from human immunodeficiency virus type 1 (HIV-1), HIV-2, and simian immunodeficiency virus (SIVMAC) are susceptible to inhibition by foscarnet and 3'-azido-3'-deoxythymidine triphosphate. Antimicrobial agents and chemotherapy, 1988, Volume: 32, Issue:11 Topics: Animals; Dideoxynucleotides; Foscarnet; HIV-1; HIV-2; Humans; Organophosphorus Compounds; Phosphonoacetic Acid; Reverse Transcriptase Inhibitors; Simian Immunodeficiency Virus; Thymine Nucleotides; Zidovudine	1988
Inhibition of human immunodeficiency virus in vitro by combinations of 3'-azido-3'-deoxythymidine and foscarnet. Antimicrobial agents and chemotherapy, 1989, Volume: 33, Issue:5 Topics: Antiviral Agents; Cells, Cultured; Fluorescent Antibody Technique; Foscarnet; HIV-1; Humans; Organophosphorus Compounds; Phosphonoacetic Acid; Zidovudine	1989
Comparative assessment of antiretrovirals in human monocyte-macrophages and lymphoid cell lines acutely and chronically infected with the human immunodeficiency virus. Journal of medical virology, 1989, Volume: 29, Issue:3 Topics: Antiviral Agents; Dose-Response Relationship, Drug; Foscarnet; Gene Products, gag; HIV; HIV Antigens; HIV Core Protein p24; Humans; Interferon Type I; Macrophages; Monocytes; Phosphonoacetic Acid; RNA, Viral; Tumor Cells, Cultured; Viral Core Proteins; Virus Replication; Zidovudine	1989
Structure-activity relationships of fluorinated nucleoside analogs and their synergistic effect in combination with phosphonoformate against human immunodeficiency virus type 1. Antimicrobial agents and chemotherapy, 1989, Volume: 33, Issue:12 Topics: Antiviral Agents; Cells, Cultured; Dideoxynucleosides; Drug Synergism; Enzyme-Linked Immunosorbent Assay; Foscarnet; HIV-1; Humans; Phosphonoacetic Acid; Structure-Activity Relationship; Virus Replication; Zidovudine	1989
Foscarnet in the treatment of cytomegalovirus retinitis in acquired immune deficiency syndrome. Ophthalmology, 1989, Volume: 96, Issue:6 Topics: Acquired Immunodeficiency Syndrome; Adult; Creatine; Cytomegalovirus Infections; Drug Therapy, Combination; Female; Foscarnet; Humans; Infusions, Intravenous; Male; Middle Aged; Organophosphorus Compounds; Phosphonoacetic Acid; Retinitis; Time Factors; Visual Acuity; Zidovudine	1989
Combinations of 3'-azido-3'-deoxythymidine (zidovudine) and phosphonoformate (foscarnet) against human immunodeficiency virus type 1 and cytomegalovirus replication in vitro. Antimicrobial agents and chemotherapy, 1989, Volume: 33, Issue:5 Topics: Antiviral Agents; Cells, Cultured; Cytomegalovirus; DNA-Directed DNA Polymerase; Drug Synergism; Foscarnet; HIV-1; Humans; Monocytes; Organophosphorus Compounds; Phosphonoacetic Acid; Viral Plaque Assay; Virus Replication; Zidovudine	1989
Acyclovir-resistant herpes in AIDS treated with foscarnet. Lancet (London, England), 1988, Aug-06, Volume: 2, Issue:8606 Topics: Acquired Immunodeficiency Syndrome; Acyclovir; Adult; Drug Resistance, Microbial; Female; Foscarnet; Herpes Genitalis; Humans; Organophosphorus Compounds; Phosphonoacetic Acid; Simplexvirus; Thymidine; Zidovudine	1988
AIDS: the virus, antivirals and vaccines. British journal of hospital medicine, 1987, Volume: 37, Issue:2 Topics: Acquired Immunodeficiency Syndrome; Antimony; Antiviral Agents; Foscarnet; Genes, Viral; HIV; Humans; Phosphonoacetic Acid; Suramin; Thymidine; Tungsten; Tungsten Compounds; Viral Vaccines; Virus Replication; Zidovudine	1987
Identification of the amino acid in the human immunodeficiency virus type 1 reverse transcriptase involved in the pyrophosphate binding of antiviral nucleoside triphosphate analogs and phosphonoformate. Implications for multiple drug resistance. Biochemical pharmacology, 1993, Dec-14, Volume: 46, Issue:12 Topics: Amino Acids; Antiviral Agents; Binding Sites; Dideoxynucleotides; Diphosphates; Drug Resistance, Microbial; Foscarnet; HIV Reverse Transcriptase; HIV-1; Kinetics; Recombinant Proteins; RNA-Directed DNA Polymerase; Thymine Nucleotides; Zidovudine	1993
Long-term foscarnet therapy not associated with the development of foscarnet-resistant human immunodeficiency virus type 1 in an acquired immunodeficiency syndrome patient. Journal of medical virology, 1994, Volume: 42, Issue:2 Topics: Acquired Immunodeficiency Syndrome; Dose-Response Relationship, Drug; Drug Resistance, Microbial; Foscarnet; Herpes Genitalis; Herpesvirus 2, Human; HIV Reverse Transcriptase; HIV-1; Humans; RNA-Directed DNA Polymerase; Time Factors; Zidovudine	1994
Drugs for AIDS and associated infections. The Medical letter on drugs and therapeutics, 1995, Oct-13, Volume: 37, Issue:959 Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Opportunistic Infections; Amphotericin B; Antifungal Agents; Antiprotozoal Agents; Antiviral Agents; Atovaquone; Candidiasis, Oral; Clindamycin; Clotrimazole; Cryptosporidiosis; Cytomegalovirus Infections; Dapsone; Didanosine; Drug Combinations; Drug Therapy, Combination; Fluconazole; Flucytosine; Folic Acid Antagonists; Foscarnet; Glucuronates; Herpes Simplex; Herpes Zoster; Humans; Isoniazid; Itraconazole; Ketoconazole; Lamivudine; Mycobacterium avium-intracellulare Infection; Naphthoquinones; Nystatin; Pentamidine; Pneumocystis Infections; Pneumonia, Pneumocystis; Prednisone; Primaquine; Reverse Transcriptase Inhibitors; Stavudine; Syphilis; Toxoplasmosis; Trimetrexate; Tuberculosis; Zalcitabine; Zidovudine	1995
Inhibition of HIV-1 replication in H9 cells by nystatin-A compared with other antiviral agents. AIDS research and human retroviruses, 1993, Volume: 9, Issue:5 Topics: Amphotericin B; Antiviral Agents; Cell Line, Transformed; Cell Survival; Foscarnet; HIV Core Protein p24; HIV Reverse Transcriptase; HIV-1; Humans; Microbial Sensitivity Tests; Nystatin; Reverse Transcriptase Inhibitors; Virus Replication; Zidovudine	1993
[Current developments in antiviral chemotherapy. Part 4: Foscarnet, zidovudine, didanosine]. Fortschritte der Medizin, 1994, May-10, Volume: 112, Issue:13 Topics: AIDS-Related Opportunistic Infections; Didanosine; Dose-Response Relationship, Drug; Drug Administration Schedule; Foscarnet; Herpesviridae Infections; HIV Infections; Humans; Zidovudine	1994
Multiple-drug-resistant mutants of feline immunodeficiency virus selected with 2',3'-dideoxyinosine alone and in combination with 3'-azido-3'-deoxythymidine. Antimicrobial agents and chemotherapy, 1994, Volume: 38, Issue:4 Topics: Animals; Antiviral Agents; Cats; Cells, Cultured; Didanosine; Drug Resistance, Microbial; Foscarnet; Immunodeficiency Virus, Feline; Mutation; Phenotype; Zalcitabine; Zidovudine	1994
Effects of reverse transcriptase inhibitors on telomere length and telomerase activity in two immortalized human cell lines. Molecular and cellular biology, 1996, Volume: 16, Issue:1 Topics: Antiviral Agents; Arabinonucleosides; Cell Division; Cell Line; Dideoxynucleosides; Dideoxynucleotides; DNA; Drug Interactions; Foscarnet; Humans; Oligonucleotide Probes; Repetitive Sequences, Nucleic Acid; Reverse Transcriptase Inhibitors; Telomerase; Telomere; Thymine Nucleotides; Zidovudine	1996
Antiviral activity of a phosphorothioate oligonucleotide complementary to human cytomegalovirus RNA when used in combination with antiviral nucleoside analogs. Antiviral research, 1995, Volume: 28, Issue:2 Topics: Antiviral Agents; Base Sequence; Cell Line; Cytomegalovirus; Drug Interactions; Foscarnet; Ganciclovir; HIV-1; Humans; Molecular Sequence Data; Nucleic Acid Synthesis Inhibitors; RNA, Viral; Thionucleotides; Virus Replication; Zalcitabine; Zidovudine	1995
Occurrence of cytomegalovirus retinitis after human immunodeficiency virus immunosuppression. Archives of ophthalmology (Chicago, Ill. : 1960), 1996, Volume: 114, Issue:7 Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; Cohort Studies; Cytomegalovirus Retinitis; Foscarnet; Ganciclovir; HIV Infections; HIV-1; Humans; Immune Tolerance; Incidence; Male; Pneumonia, Pneumocystis; Prevalence; Survival Rate; Zidovudine	1996
Synergistic inhibition of human immunodeficiency virus isolates (including 3'-azido-3'-deoxythymidine-resistant isolates) by foscarnet in combination with 2',3'-dideoxyinosine or 2',3'-dideoxycytidine. Antimicrobial agents and chemotherapy, 1996, Volume: 40, Issue:5 Topics: Antiviral Agents; Cells, Cultured; Didanosine; Drug Combinations; Drug Resistance, Microbial; Drug Synergism; Foscarnet; HIV-1; Humans; Microbial Sensitivity Tests; Monocytes; Zalcitabine; Zidovudine	1996
Zidovudine resistance is suppressed by mutations conferring resistance of human immunodeficiency virus type 1 to foscarnet. Journal of virology, 1996, Volume: 70, Issue:10 Topics: Antiviral Agents; Drug Resistance; Foscarnet; HIV-1; Humans; Molecular Sequence Data; Mutation; Zidovudine	1996
In vivo toxicity of foscarnet and zidovudine given alone or in combination. Toxicology and applied pharmacology, 1996, Volume: 139, Issue:2 Topics: Animals; Antiviral Agents; Female; Foscarnet; Hematologic Diseases; Injections, Intraperitoneal; Kidney; Kidney Diseases; Mice; Mice, Inbred C57BL; Microscopy, Electron; Organelles; Zidovudine	1996
Use of herpes simplex virus thymidine kinase to improve the antiviral activity of zidovudine. Virology, 1997, Sep-01, Volume: 235, Issue:2 Topics: Animals; Anti-HIV Agents; Cells, Cultured; Foscarnet; Herpesvirus 1, Human; Humans; Lymphocytes; Mice; Monocytes; Phosphorylation; Thymidine Kinase; Virus Replication; Zidovudine	1997
Drug susceptibility of subtypes A,B,C,D, and E human immunodeficiency virus type 1 primary isolates. AIDS research and human retroviruses, 1998, Jan-20, Volume: 14, Issue:2 Topics: Anti-HIV Agents; Cell Line, Transformed; Cells, Cultured; Didanosine; Foscarnet; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Leukocytes, Mononuclear; Nevirapine; Reverse Transcriptase Inhibitors; Ritonavir; Zidovudine	1998
Measurement of viral sequences in cerebrospinal fluid of AIDS patients with cerebral white-matter lesions using polymerase chain reaction. AIDS (London, England), 1998, Apr-16, Volume: 12, Issue:6 Topics: Adolescent; Adult; AIDS Dementia Complex; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Brain; Cytomegalovirus; Cytomegalovirus Infections; DNA, Viral; Drug Therapy, Combination; Female; Foscarnet; HIV-1; Humans; JC Virus; Leukoencephalopathy, Progressive Multifocal; Magnetic Resonance Imaging; Male; Middle Aged; Papillomavirus Infections; Polymerase Chain Reaction; RNA, Viral; Zidovudine	1998
Coresistance to zidovudine and foscarnet is associated with multiple mutations in the human immunodeficiency virus type 1 reverse transcriptase. Antimicrobial agents and chemotherapy, 1998, Volume: 42, Issue:11 Topics: Amino Acid Sequence; Anti-HIV Agents; Drug Resistance; Foscarnet; HIV Reverse Transcriptase; HIV-1; Humans; Molecular Sequence Data; Mutation; Polymerase Chain Reaction; Zidovudine	1998
Phenotypic mechanism of HIV-1 resistance to 3'-azido-3'-deoxythymidine (AZT): increased polymerization processivity and enhanced sensitivity to pyrophosphate of the mutant viral reverse transcriptase. Biochemistry, 1998, Nov-10, Volume: 37, Issue:45 Topics: Catalysis; Diphosphates; DNA, Viral; Drug Resistance, Microbial; Foscarnet; HIV Reverse Transcriptase; HIV-1; Mutagenesis, Site-Directed; Peptide Chain Termination, Translational; Phenotype; Polymers; Protein Processing, Post-Translational; Reverse Transcriptase Inhibitors; Templates, Genetic; Zidovudine	1998
Synthesis and antiviral evaluation of SATE-foscarnet prodrugs and new foscarnet-AZT conjugates. Antiviral chemistry & chemotherapy, 1998, Volume: 9, Issue:1 Topics: Anti-HIV Agents; Antiviral Agents; Cell Line; Foscarnet; Hepatitis B virus; HIV-1; Humans; Magnetic Resonance Spectroscopy; Mass Spectrometry; Microbial Sensitivity Tests; Molecular Structure; Prodrugs; Tumor Cells, Cultured; Zidovudine	1998
Biochemical characterization of HIV-1 reverse transcriptases encoding mutations at amino acid residues 161 and 208 involved in resistance to phosphonoformate. Biochemical pharmacology, 1998, Dec-15, Volume: 56, Issue:12 Topics: Amino Acids; Diphosphates; Dose-Response Relationship, Drug; Drug Resistance; Enzyme Stability; Foscarnet; HIV Reverse Transcriptase; Kinetics; Mutagenesis, Site-Directed; Nevirapine; Recombinant Proteins; Reverse Transcriptase Inhibitors; Zidovudine	1998
Survival differences associated with treatment of cytomegalovirus retinitis in Maryland patients with AIDS, 1987-1994. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 1999, Jul-01, Volume: 56, Issue:13 Topics: Adult; Age Factors; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Antiviral Agents; Cytomegalovirus Retinitis; Drug Therapy, Combination; Female; Foscarnet; Ganciclovir; Humans; Male; Maryland; Retrospective Studies; Risk Factors; Sex Factors; Zidovudine	1999
Mechanism by which phosphonoformic acid resistance mutations restore 3'-azido-3'-deoxythymidine (AZT) sensitivity to AZT-resistant HIV-1 reverse transcriptase. The Journal of biological chemistry, 2000, Mar-31, Volume: 275, Issue:13 Topics: Anti-HIV Agents; Base Sequence; DNA Primers; DNA Replication; Drug Resistance, Microbial; Foscarnet; HIV Reverse Transcriptase; HIV-1; Mutation; Recombinant Proteins; Reverse Transcriptase Inhibitors; Zidovudine	2000
In vitro anti-HIV-1 activity of sn-2-substituted 1-O-octadecyl-sn-glycero-3-phosphonoformate analogues and synergy with zidovudine. Antiviral chemistry & chemotherapy, 2000, Volume: 11, Issue:3 Topics: Antiviral Agents; Drug Carriers; Drug Combinations; Drug Synergism; Foscarnet; HeLa Cells; HIV-1; Humans; Liposomes; Viral Plaque Assay; Virus Replication; Zidovudine	2000
Phosphorylation of AZT-resistant human immunodeficiency virus type 1 reverse transcriptase by casein kinase II in vitro: effects on inhibitor sensitivity. Biochemical and biophysical research communications, 2000, Aug-18, Volume: 275, Issue:1 Topics: Amino Acid Motifs; Amino Acid Sequence; Binding Sites; Casein Kinase II; Consensus Sequence; Dideoxynucleotides; DNA; DNA Repair; Drug Resistance, Microbial; Enzyme Activation; Foscarnet; HIV Reverse Transcriptase; HIV-1; Humans; Mutation; Peptide Mapping; Phosphoric Monoester Hydrolases; Phosphorylation; Phosphoserine; Phosphothreonine; Protein Serine-Threonine Kinases; Recombinant Proteins; Reverse Transcriptase Inhibitors; Substrate Specificity; Thymine Nucleotides; Zidovudine	2000
Alkylglycerol prodrugs of phosphonoformate are potent in vitro inhibitors of nucleoside-resistant human immunodeficiency virus type 1 and select for resistance mutations that suppress zidovudine resistance. Antimicrobial agents and chemotherapy, 2001, Volume: 45, Issue:6 Topics: Drug Resistance, Microbial; Foscarnet; HIV-1; Microbial Sensitivity Tests; Prodrugs; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Virion; Zidovudine	2001
Effectiveness of rescue antiretroviral therapy including intravenously administered zidovudine and foscarnet in a child with HIV-1 enteropathy. European journal of pediatrics, 2003, Volume: 162, Issue:7-8 Topics: Anti-HIV Agents; Female; Foscarnet; HIV Enteropathy; HIV-1; Humans; Infant; RNA, Viral; Zidovudine	2003
Relationship between 3'-azido-3'-deoxythymidine resistance and primer unblocking activity in foscarnet-resistant mutants of human immunodeficiency virus type 1 reverse transcriptase. Journal of virology, 2003, Volume: 77, Issue:11 Topics: Antiviral Agents; Binding Sites; Cell Line; Deoxyadenine Nucleotides; Dideoxynucleotides; Diphosphates; DNA Primers; Drug Resistance, Viral; Foscarnet; HIV Reverse Transcriptase; HIV-1; Humans; Mutation; Templates, Genetic; Thymine Nucleotides; Zidovudine	2003
Uncharged AZT and D4T derivatives of phosphonoformic and phosphonoacetic acids as anti-HIV pronucleosides. Journal of medicinal chemistry, 2004, Jul-01, Volume: 47, Issue:14 Topics: Anti-HIV Agents; Cell Line; Drug Stability; Foscarnet; HIV-1; Humans; Hydrolysis; Phosphonoacetic Acid; Prodrugs; Stavudine; Stereoisomerism; Structure-Activity Relationship; Zidovudine	2004
Dissecting the effects of DNA polymerase and ribonuclease H inhibitor combinations on HIV-1 reverse-transcriptase activities. Biochemistry, 2005, Feb-08, Volume: 44, Issue:5 Topics: Anti-HIV Agents; Binding Sites; Butyrates; Catalysis; Dideoxynucleotides; DNA-Directed DNA Polymerase; Drug Combinations; Drug Synergism; Foscarnet; HIV Reverse Transcriptase; Hydrolysis; Kinetics; Nucleic Acid Synthesis Inhibitors; Oxazines; Reverse Transcriptase Inhibitors; Ribonuclease H; Thiophenes; Thymine Nucleotides; Zidovudine	2005
Hypersusceptibility to substrate analogs conferred by mutations in human immunodeficiency virus type 1 reverse transcriptase. Journal of virology, 2006, Volume: 80, Issue:14 Topics: Amino Acid Motifs; Catalysis; Drug Resistance, Viral; Foscarnet; HeLa Cells; HIV Reverse Transcriptase; HIV-1; Humans; Mutagenesis; Protein Binding; Protein Structure, Tertiary; Reverse Transcriptase Inhibitors; Substrate Specificity; Virus Replication; Zidovudine	2006
Selective excision of chain-terminating nucleotides by HIV-1 reverse transcriptase with phosphonoformate as substrate. The Journal of biological chemistry, 2006, Sep-22, Volume: 281, Issue:38 Topics: Antiviral Agents; Binding Sites; Catalysis; Dideoxynucleotides; Foscarnet; HIV Reverse Transcriptase; Reverse Transcriptase Inhibitors; Thymine Nucleotides; Zidovudine	2006
Long-term foscarnet therapy remodels thymidine analogue mutations and alters resistance to zidovudine and lamivudine in HIV-1. Antiviral therapy, 2007, Volume: 12, Issue:3 Topics: Amino Acid Substitution; Anti-HIV Agents; Drug Resistance, Multiple, Viral; Evolution, Molecular; Foscarnet; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Microbial Sensitivity Tests; Point Mutation; Reverse Transcriptase Inhibitors; Species Specificity; Thymidine; Time Factors; Zidovudine	2007
Mechanistic basis of zidovudine hypersusceptibility and lamivudine resistance conferred by the deletion of codon 69 in the HIV-1 reverse transcriptase coding region. Journal of molecular biology, 2008, Oct-03, Volume: 382, Issue:2 Topics: Amino Acid Sequence; Anti-HIV Agents; Codon; Crystallography, X-Ray; Deoxycytosine Nucleotides; DNA, Viral; Drug Resistance, Multiple, Viral; Foscarnet; HIV Infections; HIV Reverse Transcriptase; Humans; Lamivudine; Models, Molecular; Molecular Sequence Data; Mutation; Nucleic Acid Conformation; Protein Conformation; Reverse Transcriptase Inhibitors; Sequence Alignment; Sequence Deletion; Zidovudine	2008
Foscarnet salvage therapy efficacy is associated with the presence of thymidine-associated mutations (TAMs) in HIV-infected patients. Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2008, Volume: 43, Issue:2 Topics: Adult; Anti-HIV Agents; Drug Resistance, Viral; Drug Therapy, Combination; Female; Foscarnet; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Male; Middle Aged; Mutation; Reverse Transcriptase Inhibitors; Salvage Therapy; Stavudine; Thymidine; Treatment Outcome; Zidovudine	2008
Synthesis and in vitro activities of a new antiviral duplex drug linking Zidovudine (AZT) and Foscarnet (PFA) via an octadecylglycerol residue. Bioorganic & medicinal chemistry, 2009, Jan-01, Volume: 17, Issue:1 Topics: Antiviral Agents; Cross-Linking Reagents; Cytomegalovirus; Drug Interactions; Foscarnet; Glyceryl Ethers; HIV; Humans; Inhibitory Concentration 50; Simplexvirus; Zidovudine	2009
Response to Stegmann s, et Al. [J. Clin. Virol. 47 (1) (2010) 79-81]. Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2010, Volume: 47, Issue:3 Topics: Anti-HIV Agents; Foscarnet; HIV Infections; HIV-2; Humans; Salvage Therapy; Treatment Outcome; Viral Load; Zidovudine	2010
Treatment of HIV-related primary central nervous system lymphoma with AZT high dose, HAART, interleukin-2 and foscarnet in three patients. European journal of medical research, 2011, May-12, Volume: 16, Issue:5 Topics: Adult; Antiretroviral Therapy, Highly Active; Central Nervous System Neoplasms; Foscarnet; Humans; Interleukin-2; Lymphoma, AIDS-Related; Male; Zidovudine	2011
Successful treatment of aciclovir and foscarnet resistant Herpes simplex virus lesions with topical imiquimod in patients infected with human immunodeficiency virus type 1. Journal of medical virology, 2012, Volume: 84, Issue:2 Topics: Acyclovir; Administration, Topical; Adult; Aminoquinolines; Antiviral Agents; Drug Resistance, Viral; Foscarnet; Herpes Simplex; HIV Infections; HIV-1; Humans; Imiquimod; Lamivudine; Male; Middle Aged; Nelfinavir; Simplexvirus; Zidovudine	2012
Foscarnet, zidovudine and dolutegravir combination efficacy and tolerability for late stage HIV salvage therapy: A case-series experience. Journal of medical virology, 2016, Volume: 88, Issue:7 Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Drug Resistance, Viral; Drug Therapy, Combination; Female; Foscarnet; Heterocyclic Compounds, 3-Ring; HIV Infections; HIV-1; HIV-2; Humans; Kidney; Male; Middle Aged; Oxazines; Piperazines; Pyridones; Reverse Transcriptase Inhibitors; RNA, Viral; Salvage Therapy; Viral Load; Zidovudine	2016