Page last updated: 2024-08-23

zidovudine and emivirine

zidovudine has been researched along with emivirine in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's12 (80.00)18.2507
2000's1 (6.67)29.6817
2010's2 (13.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Baba, M; De Clercq, E; Inouye, N; Miyasaka, T; Sekiya, K; Shigeta, S; Takashima, H; Tanaka, H; Ubasawa, M; Walker, RT1
Danel, K; Larsen, E; Nielsen, C; Pedersen, EB; Vestergaard, BF1
Danel, K; Nielsen, C; Pedersen, EB1
Mao, C; Sudbeck, EA; Tuel-Ahlgren, L; Uckun, FM; Venkatachalam, TK; Vig, R1
Mao, C; Sudbeck, EA; Uckun, FM; Venkatachalam, TK1
Maher, D; Mao, C; Pendergrass, S; Tuel-Ahlgren, L; Uckun, FM; Venkatachalam, TK; Zhu, D2
Collu, G; Giliberti, G; La Colla, P; Loddo, R; Loksha, YM; Pedersen, EB; Sanna, G1
Baba, M; De Clercq, E; Miyasaka, T; Sekiya, K; Shigeta, S; Takashima, H; Tanaka, H; Ubasawa, M; Walker, RT; Yuasa, S1
Brennan, TM; Bridges, CG; Leyda, JP; Taylor, DL; Tyms, AS1
Baba, M; Inouye, N; Sadakata, Y; Sekiya, K; Takashima, H; Ubasawa, M; Yuasa, S1
Baba, M; Makino, M; Nakade, K; Okamoto, M; Yamada, K; Yuasa, S1
Baba, M; Nakade, K; Piras, G; Yuasa, S1
Danel, K; La Colla, P; Larsen, LM; Loddo, R; Pedersen, EB; Sanna, G1
Hattori, T; Kodama, EN; Li, S1

Other Studies

15 other study(ies) available for zidovudine and emivirine

ArticleYear
Synthesis and antiviral activity of 6-benzyl analogs of 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine (HEPT) as potent and selective anti-HIV-1 agents.
    Journal of medicinal chemistry, 1995, Jul-21, Volume: 38, Issue:15

    Topics: Animals; Antiviral Agents; Benzyl Compounds; HIV Infections; HIV-1; Humans; Lymphocytes; Mice; Microbial Sensitivity Tests; Structure-Activity Relationship; Thymine

1995
Synthesis and potent anti-HIV-1 activity of novel 6-benzyluracil analogues of 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine.
    Journal of medicinal chemistry, 1996, Jun-07, Volume: 39, Issue:12

    Topics: Alkylation; Antiviral Agents; Cell Division; Drug Design; HIV-1; Humans; Magnetic Resonance Spectroscopy; Molecular Structure; Structure-Activity Relationship; T-Lymphocytes; Thymine; Uracil; Virus Replication

1996
Synthesis and anti-HIV-1 activity of novel 2,3-dihydro-7H-thiazolo[3,2-a]pyrimidin-7-ones.
    Journal of medicinal chemistry, 1998, Jan-15, Volume: 41, Issue:2

    Topics: Alkylation; Anti-HIV Agents; Cell Line; HIV Reverse Transcriptase; HIV-1; Humans; Magnetic Resonance Spectroscopy; Mesylates; Pyrimidines; Pyrimidinones; Reverse Transcriptase Inhibitors; T-Lymphocytes; Thiazoles; Thymine; Uracil; Virus Replication

1998
5-Alkyl-2-[(methylthiomethyl)thio]-6-(benzyl)-pyrimidin-4-(1H)-ones as potent non-nucleoside reverse transcriptase inhibitors of S-DABO series.
    Bioorganic & medicinal chemistry letters, 1998, Jun-16, Volume: 8, Issue:12

    Topics: Anti-HIV Agents; Cell-Free System; Drug Design; HIV-1; Humans; Monocytes; Pyrimidinones; Reverse Transcriptase Inhibitors; Sulfides

1998
Rational design of N-[2-(2,5-dimethoxyphenylethyl)]-N'-[2-(5-bromopyridyl)]-thiourea (HI-236) as a potent non-nucleoside inhibitor of drug-resistant human immunodeficiency virus.
    Bioorganic & medicinal chemistry letters, 1999, Jun-07, Volume: 9, Issue:11

    Topics: Anti-HIV Agents; Delavirdine; Drug Design; Humans; Inhibitory Concentration 50; Kinetics; Models, Molecular; Nevirapine; Pyridines; Thiourea

1999
N-[2-(1-cyclohexenyl)ethyl]-N'-[2-(5-bromopyridyl)]-thiourea and N'-[2-(1-cyclohexenyl)ethyl]-N'-[2-(5-chloropyridyl)]-thiourea as potent inhibitors of multidrug-resistant human immunodeficiency virus-1.
    Bioorganic & medicinal chemistry letters, 1999, Sep-20, Volume: 9, Issue:18

    Topics: Aminopyridines; Anti-HIV Agents; Drug Resistance, Microbial; Drug Resistance, Multiple; HIV Reverse Transcriptase; HIV-1; Humans; Models, Molecular; Reverse Transcriptase Inhibitors; Thiourea

1999
N'-[2-(2-thiophene)ethyl]-N'-[2-(5-bromopyridyl)] thiourea as a potent inhibitor of NNI-resistant and multidrug-resistant human immunodeficiency virus-1.
    Bioorganic & medicinal chemistry letters, 1999, Dec-20, Volume: 9, Issue:24

    Topics: Anti-HIV Agents; Cells, Cultured; HIV-1; Humans; Microbial Sensitivity Tests; Models, Molecular; Pyridines; Reverse Transcriptase Inhibitors; Thiourea; Virus Replication

1999
Synthesis of novel fluoro analogues of MKC442 as microbicides.
    Journal of medicinal chemistry, 2014, Jun-26, Volume: 57, Issue:12

    Topics: Anti-HIV Agents; Cell Line; Drug Resistance, Viral; HIV Protease Inhibitors; HIV Reverse Transcriptase; HIV-1; Humans; Mutation; Pyrimidinones; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Uracil

2014
Preclinical evaluation of MKC-442, a highly potent and specific inhibitor of human immunodeficiency virus type 1 in vitro.
    Antimicrobial agents and chemotherapy, 1994, Volume: 38, Issue:4

    Topics: Antiviral Agents; Cells, Cultured; Drug Evaluation, Preclinical; Drug Resistance, Microbial; Drug Synergism; HIV Reverse Transcriptase; HIV-1; HIV-2; Humans; Reverse Transcriptase Inhibitors; Uracil; Virus Replication; Zidovudine

1994
The inhibition of human immunodeficiency virus type 1 in vitro by a non-nucleoside reverse transcriptase inhibitor MKC-442, alone and in combination with other anti-HIV compounds.
    Antiviral research, 1995, Volume: 26, Issue:2

    Topics: Antiviral Agents; Cells, Cultured; Cytotoxicity Tests, Immunologic; Didanosine; Drug Interactions; HIV Reverse Transcriptase; HIV-1; Humans; Indolizines; Isoquinolines; Leukocytes, Mononuclear; Molecular Structure; Nevirapine; Pyridines; Quinolines; Reverse Transcriptase Inhibitors; Saquinavir; Uracil; Zalcitabine; Zidovudine

1995
Selective and synergistic inhibition of human immunodeficiency virus type 1 reverse transcriptase by a non-nucleoside inhibitor, MKC-442.
    Molecular pharmacology, 1993, Volume: 44, Issue:4

    Topics: Antiviral Agents; Dideoxynucleotides; Drug Synergism; HIV Reverse Transcriptase; HIV-1; Kinetics; Reverse Transcriptase Inhibitors; Thymine Nucleotides; Uracil; Virus Replication; Zidovudine

1993
Complete inhibition of viral breakthrough by combination of MKC-442 with AZT during a long-term culture of HIV-1 infected cells.
    Antiviral research, 1996, Volume: 31, Issue:1-2

    Topics: Acetamides; Acetophenones; Cell Line, Transformed; HIV; HIV Core Protein p24; HIV-1; Humans; Nevirapine; Pyridines; Reverse Transcriptase Inhibitors; Uracil; Zidovudine

1996
Three-drug combination of MKC-442, lamivudine and zidovudine in vitro: potential approach towards effective chemotherapy against HIV-1.
    AIDS (London, England), 1997, Mar-15, Volume: 11, Issue:4

    Topics: Anti-HIV Agents; Cell Line, Transformed; Cells, Cultured; Drug Synergism; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Leukocytes, Mononuclear; Uracil; Zidovudine

1997
Synthesis and antiviral activity of new dimeric inhibitors against HIV-1.
    Bioorganic & medicinal chemistry, 2008, Jan-01, Volume: 16, Issue:1

    Topics: Anti-HIV Agents; Dimerization; HIV-1; Humans; Mutation; Pyrimidines; Uracil; Zidovudine

2008
Epigallocatechin gallate inhibits the HIV reverse transcription step.
    Antiviral chemistry & chemotherapy, 2011, Jul-04, Volume: 21, Issue:6

    Topics: Anti-HIV Agents; Catechin; Drug Evaluation, Preclinical; Drug Synergism; HeLa Cells; HIV Infections; HIV Reverse Transcriptase; HIV-1; HIV-2; Humans; Reverse Transcriptase Inhibitors; Reverse Transcription; Uracil; Zidovudine

2011