Page last updated: 2024-08-23

zidovudine and dipyridamole

zidovudine has been researched along with dipyridamole in 28 studies

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-19902 (7.14)18.7374
1990's12 (42.86)18.2507
2000's4 (14.29)29.6817
2010's9 (32.14)24.3611
2020's1 (3.57)2.80

Authors

AuthorsStudies
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Chen, X; Lin, X; Skolnik, S; Wang, J1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Boon, GD; Chan, TC; Redmond, R; Shaffer, L1
Domin, BA; Hajian, G; Koszalka, GW; Mahony, WB; Porter, DJ; Zimmerman, TP1
Taniki, T; Weber, G; Zhen, YS1
Broder, S; Kageyama, S; Mitsuya, H; Yarchoan, R1
Szebeni, J1
Bunow, B; Schinazi, RF; Szebeni, J; Wahl, LM; Wahl, SM; Weinstein, JN; Weislow, OS1
Betageri, GV; Corcoran, M; Hung, K; Patel, SS; Szebeni, J; Wahl, LM; Weinstein, JN1
Fine, RL; Friedmann, RM; Gartner, S; Popovic, M; Skaleric, U; Szebeni, J; Wahl, LM; Wahl, SM; Weinstein, JN1
Wyngaarden, JB1
Bawdon, RE; Kaul, S; Sobhi, S1
Flexner, C; Hendrix, CW; Kuwahara, S; Lietman, PS; Pennypacker, S; Szebeni, J; Weinstein, JN1
Abbott, NJ; Begley, DJ; Jezequel, SG; Khan, EU; Reichel, A; Roffey, SJ1
Fayz, S; Inaba, T1
Büchele, T; Dempke, W; Grothey, A; Schmoll, HJ1
Baba, M; Cheng, YC; Tanaka, H; Wang, X1
Nosengo, N1

Reviews

5 review(s) available for zidovudine and dipyridamole

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Targeted therapy of human immunodeficiency virus-related disease.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 1991, Volume: 5, Issue:10

    Topics: Acquired Immunodeficiency Syndrome; Adenine; Antiviral Agents; CD4 Antigens; Didanosine; Dideoxynucleosides; Dipyridamole; Drug Synergism; Gene Expression Regulation, Viral; Genes, nef; Genes, rev; Genes, tat; HIV; HIV Protease; Interferon Type I; Organophosphonates; RNA-Directed DNA Polymerase; Stavudine; Transcription, Genetic; Zalcitabine; Zidovudine

1991
[A new drug in a new role: dipyridamole in the treatment of HIV-1 infections?].
    Orvosi hetilap, 1991, Sep-01, Volume: 132, Issue:35

    Topics: Acquired Immunodeficiency Syndrome; Dipyridamole; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Zidovudine

1991
Synergistic drug combinations in AIDS therapy. Dipyridamole/3'-azido-3'-deoxythymidine in particular and principles of analysis in general.
    Annals of the New York Academy of Sciences, 1990, Volume: 616

    Topics: Acquired Immunodeficiency Syndrome; Dideoxynucleosides; Dipyridamole; Drug Synergism; Drug Therapy, Combination; Electronic Data Processing; Zidovudine

1990
Where do we stand with 5-fluorouracil?
    Seminars in oncology, 1999, Volume: 26, Issue:6

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Chronotherapy; Colorectal Neoplasms; Dipyridamole; Drug Synergism; Fluorouracil; Humans; Interferons; Leucovorin; Levamisole; Methotrexate; Phosphonoacetic Acid; Radiation-Sensitizing Agents; Trimetrexate; Zidovudine

1999

Other Studies

23 other study(ies) available for zidovudine and dipyridamole

ArticleYear
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Attenuation of intestinal absorption by major efflux transporters: quantitative tools and strategies using a Caco-2 model.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:2

    Topics: Adenosine; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Sub-Family B Member 4; ATP-Binding Cassette Transporters; Biological Transport; Caco-2 Cells; Chromatography, Liquid; Dibenzocycloheptenes; Diketopiperazines; Drug Discovery; Heterocyclic Compounds, 4 or More Rings; Humans; Intestinal Absorption; Mass Spectrometry; Models, Biological; Neoplasm Proteins; Pharmaceutical Preparations; Predictive Value of Tests; Propionates; Quinolines; Substrate Specificity

2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
Antiviral nucleoside toxicity in canine bone marrow progenitor cells and its relationship to drug permeation.
    European journal of haematology, 1992, Volume: 49, Issue:2

    Topics: Animals; Biological Transport, Active; Colony-Forming Units Assay; Didanosine; Dipyridamole; Dogs; Dose-Response Relationship, Drug; Erythrocytes; Female; Granulocytes; Hematopoietic Stem Cells; In Vitro Techniques; Macrophages; Zalcitabine; Zidovudine

1992
Membrane permeation characteristics of 5'-modified thymidine analogs.
    Molecular pharmacology, 1992, Volume: 41, Issue:5

    Topics: Antiviral Agents; Biological Transport; Dilazep; Dipyridamole; Erythrocyte Membrane; Erythrocytes; Humans; Kinetics; Nucleosides; Purines; Pyrimidines; Radioisotope Dilution Technique; Thymidine; Tritium; Zidovudine

1992
Azidothymidine and dipyridamole as biochemical response modifiers: synergism with methotrexate and 5-fluorouracil in human colon and pancreatic carcinoma cells.
    Oncology research, 1992, Volume: 4, Issue:2

    Topics: Adenocarcinoma; Cell Division; Cell Line; Cell Survival; Colonic Neoplasms; Dipyridamole; DNA Replication; Drug Screening Assays, Antitumor; Drug Synergism; Fluorouracil; Humans; Methotrexate; Pancreatic Neoplasms; Thymidine; Tumor Stem Cell Assay; Zidovudine

1992
Effect of dipyridamole on transport and phosphorylation of thymidine and 3'-azido-3'-deoxythymidine in human monocyte/macrophages.
    Biochemical pharmacology, 1990, Aug-15, Volume: 40, Issue:4

    Topics: Biological Transport; Cells, Cultured; Dipyridamole; Humans; Macrophages; Monocytes; Phosphorylation; Thymidine; Zidovudine

1990
Dipyridamole potentiates the inhibition by 3'-azido-3'-deoxythymidine and other dideoxynucleosides of human immunodeficiency virus replication in monocyte-macrophages.
    Proceedings of the National Academy of Sciences of the United States of America, 1989, Volume: 86, Issue:10

    Topics: Antiviral Agents; Biological Transport; Bone Marrow; Bone Marrow Cells; Cell Survival; Dideoxynucleosides; Dipyridamole; Drug Synergism; HIV; Humans; In Vitro Techniques; Interferon Type I; Macrophages; Monocytes; Virus Replication; Zalcitabine; Zidovudine

1989
From the National Institutes of Health.
    JAMA, 1989, Jul-07, Volume: 262, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Carcinoma; Colorectal Neoplasms; Dipyridamole; Humans; Interferon Type I; Zidovudine

1989
The ex vivo transfer of the anti-HIV nucleoside compound d4T in the human placenta.
    Gynecologic and obstetric investigation, 1994, Volume: 38, Issue:1

    Topics: Diffusion; Dipyridamole; Female; Fetal Blood; Gestational Age; Humans; Maternal-Fetal Exchange; Perfusion; Placenta; Pregnancy; Stavudine; Thymidine; Zidovudine

1994
Effect of dipyridamole on zidovudine pharmacokinetics and short-term tolerance in asymptomatic human immunodeficiency virus-infected subjects.
    Antimicrobial agents and chemotherapy, 1994, Volume: 38, Issue:5

    Topics: Adult; Dipyridamole; Drug Combinations; Drug Interactions; HIV Seropositivity; Humans; Iodine Radioisotopes; Male; Orosomucoid; Zidovudine

1994
The effect of drug lipophilicity on P-glycoprotein-mediated colchicine efflux at the blood-brain barrier.
    International journal of clinical pharmacology and therapeutics, 1998, Volume: 36, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood-Brain Barrier; Cell Line; Colchicine; Cyclosporine; Dipyridamole; Lipids; Rats; Solubility; Verapamil; Zidovudine

1998
Zidovudine azido-reductase in human liver microsomes: activation by ethacrynic acid, dipyridamole, and indomethacin and inhibition by human immunodeficiency virus protease inhibitors.
    Antimicrobial agents and chemotherapy, 1998, Volume: 42, Issue:7

    Topics: Chromatography, Thin Layer; Dipyridamole; Enzyme Activation; Enzyme Inhibitors; Enzyme Repression; Ethacrynic Acid; Humans; Indomethacin; Microsomes, Liver; Oxidoreductases; Zidovudine

1998
Retention of metabolites of 2',3'-didehydro-3'-deoxy-4'-ethynylthymidine, a novel anti-human immunodeficiency virus type 1 thymidine analog, in cells.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:8

    Topics: Anti-HIV Agents; Biological Transport; Cell Line; Cell Line, Tumor; Chromatography, High Pressure Liquid; Dipyridamole; Humans; Multidrug Resistance-Associated Proteins; Phosphodiesterase Inhibitors; Phosphorylation; Stavudine; Thymidine; Zidovudine

2009
Can you teach old drugs new tricks?
    Nature, 2016, 06-16, Volume: 534, Issue:7607

    Topics: Animals; Azoles; Bipolar Disorder; Carbazoles; Clinical Trials, Phase II as Topic; Dipyridamole; Drug Approval; Drug Evaluation, Preclinical; Drug Industry; Drug Repositioning; Drugs, Generic; Dry Eye Syndromes; Epilepsy; Humans; Isoindoles; Mice; Multiple Sclerosis; Neoplasms; Off-Label Use; Organoselenium Compounds; Patents as Topic; Sildenafil Citrate; Zidovudine

2016