Compounds > zidovudine
Page last updated: 2024-08-23

zidovudine and dioxolane-thymine

zidovudine has been researched along with dioxolane-thymine in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (50.00)18.2507
2000's2 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ahn, SK; Alves, AJ; Beach, JW; Choi, BG; Chu, CK; Jeong, LS; Kim, HO; Schinazi, RF; Van Roey, P1
Beach, JW; Cannon, DL; Chu, CK; Jeong, LS; Kim, HO; Nampalli, S; Schinazi, RF; Shanmuganathan, K1
Asif, G; Chu, CK; Delinsky, D; Hurwitz, SJ; McClure, HM; Narayanasamy, J; Obikhod, A; Schinazi, RF1
Chu, CK; Grier, JP; Liang, Y; Rapp, KL; Schinazi, RF; Sharon, A1

Other Studies

4 other study(ies) available for zidovudine and dioxolane-thymine

ArticleYear
Asymmetric synthesis of 1,3-dioxolane-pyrimidine nucleosides and their anti-HIV activity.
    Journal of medicinal chemistry, 1992, May-29, Volume: 35, Issue:11

    Topics: Antiviral Agents; Cytosine; Dioxolanes; HIV-1; Humans; Leukocytes, Mononuclear; Molecular Conformation; Molecular Structure; Pyrimidine Nucleosides; Structure-Activity Relationship

1992
L-beta-(2S,4S)- and L-alpha-(2S,4R)-dioxolanyl nucleosides as potential anti-HIV agents: asymmetric synthesis and structure-activity relationships.
    Journal of medicinal chemistry, 1993, Mar-05, Volume: 36, Issue:5

    Topics: Antiviral Agents; Cell Line; Cell Survival; Cytosine; Dioxolanes; HIV-1; Humans; Molecular Structure; Purines; Pyrimidines; Structure-Activity Relationship

1993
Pharmacokinetics of the anti-human immunodeficiency virus agent 1-(beta-D-dioxolane)thymine in rhesus monkeys.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:7

    Topics: Administration, Oral; Animals; Antiviral Agents; Area Under Curve; Calibration; Chromatography, High Pressure Liquid; Dioxolanes; Female; Half-Life; HIV-1; Injections, Intravenous; Macaca mulatta; Mass Spectrometry; Metabolic Clearance Rate; Molecular Structure; Reference Standards; Reproducibility of Results; Thymine

2007
5'-O-Aliphatic and amino acid ester prodrugs of (-)-beta-D-(2R,4R)-dioxolane-thymine (DOT): synthesis, anti-HIV activity, cytotoxicity and stability studies.
    Bioorganic & medicinal chemistry, 2009, Feb-01, Volume: 17, Issue:3

    Topics: Animals; Anti-HIV Agents; Cell Line; Chlorocebus aethiops; Dioxolanes; Drug Stability; Half-Life; Humans; Leukocytes, Mononuclear; Prodrugs; Stereoisomerism; Thymine; Vero Cells

2009