Page last updated: 2024-08-23

zidovudine and didanosine

zidovudine has been researched along with didanosine in 957 studies

Research

Studies (957)

TimeframeStudies, this research(%)All Research%
pre-19905 (0.52)18.7374
1990's693 (72.41)18.2507
2000's200 (20.90)29.6817
2010's56 (5.85)24.3611
2020's3 (0.31)2.80

Authors

AuthorsStudies
Gumus, F; Ishaq, KS; Iyer, N; Kucera, LS; Marasco, CJ; Meyer, KL; Morris-Natschke, SL; Piantadosi, C; Surles, JR; Wallen, CA1
Breslin, HJ; De Clercq, E; Diamond, CJ; Grous, PP; Ho, CY; Kukla, MJ; Miranda, M; Pauwels, R; Rodgers, JD; Sherrill, RG1
Andries, K; Breslin, HJ; Fedde, CL; Kukla, MJ; Miranda, M; Pauwels, R; Raeymaekers, A; Scott, MK; Sherrill, RG; Van Gelder, J1
Aoki, S; Driscoll, JS; Ford, H; Kelley, JA; Kojima, E; Mitsuya, H; Murakami, K; Shirasaka, T; Yoshioka, H1
Aoki, S; Barchi, JJ; Driscoll, JS; Ford, H; Kelley, JA; Marquez, VE; Mitsuya, H; Shirasaka, T1
Antonenko, SV; Chentsova, NP; Kukhar, VP; Luik, AI; Poda, GI; Tetko, IV1
abu Sheikha, G; Cappellacci, L; de Montis, A; Franchetti, P; Grifantini, M; La Colla, P; Loi, AG; Messini, L; Spiga, MG; Tramontano, E1
Driscoll, JS; Ford, H; Kelley, JA; Marquez, VE; Mitsuya, H; Shirasaka, T; Siddiqui, MA1
Andrei, G; Balzarini, J; Blache, Y; Chapat, JP; Chavignon, O; De Clercq, E; Debouzy, JC; Elhakmaoui, A; Essassi, EM; Gueiffier, A; Kerbal, A; Lhassani, M; Snoeck, R; Teulade, JC; Witvrouw, M1
Gam, J; Kim, DK; Kim, HT; Kim, KH; Kim, YW; Lim, J1
Cha, SH; Endou, H; Kanai, Y; Kimura, M; Sekine, T; Tsuda, M; Wada, S1
Bader, JP; Cragg, GM; Newman, DJ; Yang, SS1
Alam, N; Hong, J; Im, KS; Jung, JH; Lee, CK; Li, F; Liu, Y; Wang, W1
Chen, IS; Ishikawa, T; Nishigaya, K; Takami, K; Tsai, IL; Uchikoshi, H1
Jolivette, LJ; Ward, KW1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Lund, KC; Peterson, LL; Wallace, KB1
Ainsworth, J; Booth, C; Bradshaw, D; Geretti, AM; Malik, S; Pattery, T; Van Houtte, M; Waters, A1
Anderson, DJ; Gottlieb, GS; Preston, BD; Pyrak, CL; Smith, RA1
Beadle, JR; Bradley, M; Farasati, NA; Hostetler, KY; Huang, Y; Meier, C; Randhawa, P; Sauerbrei, A; Zemlicka, J1
Lombardo, F; Obach, RS; Waters, NJ1
Haas, RH; Naviaux, RK; Saitoh, A; Salva, NG; Spector, SA; Wong, JK1
Chou, KC; González-Díaz, H; Martinez de la Vega, O; Prado-Prado, FJ; Ubeira, FM; Uriarte, E1
Bachmann, MH; Fessel, WJ; Kagan, RM; Mitsuya, Y; Shafer, RW; Shahriar, R; Varghese, V1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Amblard, F; Bassit, L; Bondada, L; Coats, SJ; Detorio, M; Grier, J; Hernandez-Santiago, BI; Koontz, D; Mellors, JW; Rapp, KL; Schinazi, RF; Sluis-Cremer, N1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Almond, MR; Buckheit, RW; Hartman, T; Keilholz, L; Lampert, BM; Lanier, ER; Mankowski, MK; Osterling, MC; Painter, GR; Ptak, RG1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Azas, N; Casano, G; Dumètre, A; Hutter, S; Pannecouque, C; Robin, M1
Ekins, S; Williams, AJ; Xu, JJ1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Chen, W; Chen, X; De Clercq, E; Li, D; Li, X; Liu, X; Pannecouque, C; Tian, Y; Zhan, P1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Balzarini, J; Chen, FE; Chen, WX; Daelemans, D; De Clercq, E; He, QQ; Pannecouque, C; Wu, HQ; Yan, ZH1
Balzarini, J; Chen, X; De Clercq, E; Li, Z; Liu, H; Liu, X; Pannecouque, C; Xie, Z; Zhan, P; Zhang, L; Zhao, T1
Costa, J; Dumontet, V; Leyssen, P; Litaudon, M; Neyts, J; Nothias-Scaglia, LF; Pannecouque, C; Paolini, J; Retailleau, P; Roussi, F1
Chen, W; De Clercq, E; Liu, X; Liu, Z; Pannecouque, C; Zhan, P1
Chen, FE; Chen, WX; Daelemans, D; De Clercq, E; He, QQ; Pannecouque, C; Wu, HQ; Yao, J1
Balzarini, J; Chen, W; De Clercq, E; Fu, L; Huang, B; Li, C; Liu, H; Liu, T; Liu, X; Pannecouque, C; Sun, Y; Yu, M; Zhan, P1
Ashok, P; Balzarini, J; Chander, S; Murugesan, S; Pannecouque, C1
Chen, W; De Clercq, E; Fu, L; Huang, B; Li, C; Li, X; Liang, X; Liu, H; Liu, T; Liu, X; Pannecouque, C; Sun, Y; Zhan, P1
Girard-Valenciennes, E; Grondin, I; Leyssen, P; Litaudon, M; Neyts, J; Olivon, F; Palenzuela, H; Pannecouque, C; Roussi, F1
Arumugam, SR; Badri, KR; He, JJ; Visalli, RJ; Zhang, X; Zhao, H; Ziobrowski, H1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Chen, X; Daelemans, D; De Clercq, E; Huang, B; Kang, D; Li, W; Liu, X; Meng, Q; Pannecouque, C; Zhan, P1
Bhatt, HG; Pannecouque, C; Patel, BD; Patel, SB1
Chizhov, AO; Geisman, AN; Khandazhinskaya, AL; Kochetkov, SN; Naesens, L; Novikov, MS; Ozerov, AA; Pannecouque, C; Seley-Radtke, KL; Valuev-Elliston, VT1
Bingöl Özakpınar, Ö; De Clercq, E; Küçükgüzel, İ; Kulabaş, N; Özsavcı, D; Pannecouque, C; Tatar, E1
Buckheit, RW; Cushman, M; Hartman, TL; Hoshi, A; Okazaki, M; Pannecouque, C; Sakamoto, T; Takayama, J; Xuan, M1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y1
Camarasa, MJ; de Castro, S1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Gao, Q; Gu, Z; Li, X; Parniak, MA; Wainberg, MA1
Ayehunie, S; Britton, S; Sönnerborg, A; Strannegård, O; Wondimu, Z1
Fauci, AS1
Caliò, R; Perno, CF1
Brett, CM; Giacomini, KM; Hui, AC; Wu, X; Yuan, G1
Johnson, VA2
Kahn, J1
Balzarini, J; Bergamini, A; Calio, R; De Clercq, E; Milanese, G; Pauwels, R; Perno, CF; Rocchi, G; Yarchoan, R1
Husson, RN; Pizzo, PA1
Hammer, SM; McLeod, GX2
Saag, MS2
Skowron, G1
Watson, AJ; Wilburn, LM1
Garfunkel, AA; Glick, M1
Boon, GD; Chan, TC; Redmond, R; Shaffer, L1
Blakeslee, JR; Mathes, LE; Olsen, RG; Tanabe-Tochikura, A; Tochikura, TS1
Bawdon, RE; Dax, J; Sobhi, S1
Foerster, M; Kastner, U; Neubert, R1
Bjornson, DC; Cortese, M1
Lynn, LA1
Morse, GD; O'Donnell, AM; Shelton, MJ1
Beall, G; Brown, M; Cross, A; Crumpacker, CS; Kahn, JO; Lagakos, SW; Liou, SH; Pettinelli, C; Richman, DD; Volberding, PA1
Lane, HC1
Aboulker, JP; Darbyshire, JH1
Martin, ES; Rathbun, RC1
Barsanti, L; Batoni, G; Ceccherini Nelli, L; Chirianni, A; Liuzzi, G; Piazza, M; Santoro, G; Tullio Cataldo, P1
Cooper, DA; Danner, SA; Lange, JM1
Broder, S; Caliò, R; Cooney, DA; Foli, A; Gao, WY; Hao, Z; Hartman, NR; Johns, DG; Perno, CF; Yarchoan, R1
Cameron, JM; Cammack, N; Coates, JA; Jenkinson, HJ; Jowett, AJ; Jowett, MI; Pearson, BA; Penn, CR; Rouse, PL; Viner, KC1
Agrawal, KC; Gogu, SR; Malter, JS1
Blais, FX1
Friedmann, PD; Roberts, MS; Saitz, R1
Venes, DJ1
Behrman, RE; Feigal, DW; Kammerman, LA1
Butler, KM; Husson, RN; Lewis, LL; Patronas, N; Pizzo, PA; Saini, R1
Allan, JD; Beltangady, M; Canetta, R; Cooley, TP; Dolin, R; Kelley, S; Lambert, J; Liebman, HA; Rozencweig, M; Schacter, LP1
Benson, CA; Kessler, HA; Pottage, JC; Sha, BE; Urbanski, P1
Grieco, MH; Hargrove, D; McHugh, T; McKinley, GF; Reddy, MM; Winger, EE1
Heinzl, S1
Hsiung, GD; Medina, DJ; Mellors, JW1
Hammer, SM; Ladd, EA; McGrath, JM; McLeod, GX1
Erickson, J; Kageyama, S; Kempf, DJ; Mitsuya, H; Norbeck, DW; Plattner, JJ; Shirasaka, T; Weinstein, JN1
Canipari, R; Coluzzi, ML; Cossu, G; Cusella De Angelis, MG; Floridia, M; Mezzogiorno, A; Sieh, E; Vella, S1
Albert, J; Cox, SW; Uhlén, M; Wahlberg, J; Wahren, B1
Finco, TS; Gallo, JM; Mehta, MU; Qian, M; Swagler, AR; Viswanathan, CT1
Armstrong, JA; Asuncion, C; Gueverra, L; Ho, M; O'Marro, SD1
DiJohn, D; Karpatkin, M; Kaul, A; Krasinski, K; Lawrence, R; Leibovitz, E; Nardi, M; Pollack, H; Quee, CS; Rigaud, M1
Gupta, I; Kocher, J; Miller, AJ; Perz, J; Scully, M; Weisholtz, SJ1
Batash, S; Falkenstein, D; Hollander, D; Katz, K; Ma, T; Raicht, R; Weinshel, E1
Gao, Q; Gu, Z; Parniak, MA; Wainberg, MA1
Cohen, JB; Derish, PA; Hernandez, SR; Hirozawa, AM; Lemp, GF; McKinney, KC1
Au, JL; Wientjes, MG1
Groopman, JE; Molina, JM1
Keilbaugh, SA; Prusoff, WH; Simpson, MV1
Rousseau, F; Sereni, D1
Goldsmith, MF1
Fischl, MA1
Allan, JD; Canetta, R; Connolly, KJ; Fitch, H; Groopman, JE; Jackson-Pope, L; McLaren, C2
Butler, K; Husson, R; Marshall, D; Pizzo, PA; Roilides, E; Venzon, D1
Ayisi, NK; Gupta, SV; Qualtiere, LF1
Cao, W; Fuchs, BA; Germolec, DR; Luster, MI; Munson, AE; Prejean, JD; Rosenthal, GJ; Shopp, G; Thompson, MB; Tomaszewski, JE1
LeBourdais, E1
Coplan, PM; Nolan, LL1
Pinching, AJ2
Gallo, JM; Qian, MX; Swagler, AR1
Andries, K; Breslin, HJ; Desmyter, J; Heykants, J; Kukla, MJ; Pauwels, R; Raeymaeckers, A; Schols, D; Van Gelder, J; Woestenborghs, R1
Hirsch, MS2
Horgan, J1
Ashorn, P; Berger, EA; Chaudhary, VK; FitzGerald, DJ; Moss, B; Pastan, I; Weinstein, JN1
Chatis, PA; Crumpacker, CS; Eigenrauch, HA; Japour, AJ1
Averett, DR; Burns, CL; Dornsife, RE; Huang, AT; Koszalka, GW; Panella, TJ; St Clair, MH1
Broder, S; Kageyama, S; Mitsuya, H; Yarchoan, R1
Broder, S; Mitsuya, H; Perno, CF; Pluda, JM; Yarchoan, R1
Byington, RE; Chou, TC; D'Aquila, RT; Eron, JJ; Hirsch, MS; Johnson, VA; Merrill, DP; Videler, JA1
Bach, MC; Kellam, P; Kemp, SD; King, DM; Larder, BA; Martin, JL; St Clair, MH; Tudor-Williams, G; Vavro, CL1
Mitsuya, H2
Fernández-Cruz, E1
Cersosimo, RJ; Matthews, SJ; Spivack, ML1
Gao, Q; Gu, ZX; Li, XG; Parniak, MA; Wainberg, MA1
Belfort, R; Butler, KM; Caruso, R; de Smet, MD; Husson, RN; Lopez, JS; Nussenblatt, RB; Pizzo, PA; Rubin, B; Whitcup, SM1
Back, DJ; Eagling, VA; Macleod, R; Sim, SM1
Healy, B1
Beall, G; Boyar, A1
Grieco, MH; McKinley, GF; Reddy, MM1
McCune, JM; Péault, B; Rabin, L; Streeter, PR1
Merigan, TC1
Chen, CH; Cheng, YC; Vazquez-Padua, M1
Kaneshima, H; Machado, SG; McCune, JM; Namikawa, R; Outzen, H; Rabin, L; Shih, CC1
Crumpacker, C; Finberg, RW; Heagy, W; Lopez, PA1
Jost, J; Lüthy, R1
Goldspiel, BR1
Connor, E1
Back, DJ; Breckenridge, AM; Sim, SM1
Hirschel, B; Vanhems, P1
Aoki-Sei, S; Broder, S; Cooney, DA; Ford, H; Fujii, H; Gilbert, DA; Johns, DG; Mitsuya, H; O'Brien, MC1
Foth, H; Frijus-Plessen, N; Kahl, GF; Michaelis, HC1
Broder, S; Brouwers, P; Hartman, N; Johns, DG; Mitsuya, H; Pluda, JM; Thomas, RV; Wyvill, KM; Yarchoan, R1
Bach, MC1
Cooper, EC2
Hoth, D1
Pizzo, PA; Roilides, E; Rubin, M; Venzon, D1
Marwick, C1
McGourty, C1
de Noronha, F; Postie, L; Roneker, C; Tavares, L1
González-Lahoz, J; Soriano, V1
Portegies, P1
Gallicchio, VS; Hughes, NK2
Cauda, R; Donelli, G; Landay, AL; Lucia, MB; Malorni, W; Ortona, L1
Carr, A; Cooper, DA; Loewenthal, M1
Mitsuya, H; Shirasaka, T1
Akagi, K; Okuyama, N1
Kurimura, T; Sakamoto, T; Tsuchie, H1
Koerber, KL; Pagano, JS; Smith, MS1
Allen, LB; Buckheit, RW; Chirigos, MA; Germany-Decker, J; Hollingshead, MG; Janssen, PA; Shannon, WM1
Bozzette, SA; Hay, J; Parker, R1
Balfour, HH; Erice, A1
Neuzil, KM1
Cameron, J; Fang, H; Gao, Q; Goldberg, E; Gu, Z; Parniak, MA; Salomon, H; Wainberg, MA1
Connell, EV; Hsu, MC; Richman, DD1
Efron, B; Katzenstein, DA; Kozal, MJ; Kroodsma, K; Merigan, TC; Shafer, RW; Winters, MA1
Caliendo, AM; Hirsch, MS1
Auclair, C; Beaulieu, R; Boulerice, F; Gill, J; Montaner, JS; Phillips, P; Rachlis, A; Schindzielorz, A; Schlech, W; Smaldone, L1
Britton, S; Julander, I1
Au, JL; Mathes, LE; Mukherji, E1
Biteau, N; Doignon, F; Fleury, HJ; Masquelier, B; Michelet, C; Morlat, P; Pellegrin, I; Ragnaud, JM; Ruffault, A1
Andries, K; Breslin, HJ; De Clercq, E; Debyser, Z; Desmyter, J; Janssen, MA; Kukla, MJ; Pauwels, R; Schols, D; Woestenborghs, R1
Besemer, D; Eastman, PS; Kolberg, J; Stempien, M; Urdea, M1
Aguiniga, E; Iversen, AK; Katzenstein, DA; Merigan, TC; Shafer, RW; Winters, MA1
Brennan, TM; Bridges, CG; Leyda, JP; Taylor, DL; Tyms, AS1
Barry, DW; Pennington, KN; Rooney, J; St Clair, MH1
Farr, SS; Kammerman, LA; Kazempour, K1
Stephenson, J1
Choo, V1
Dillner, L1
Dalakas, MC; Lewis, W1
Stretcher, BN1
Flexner, C; Ginsberg, R; Hamzeh, FM; Haubrich, RH; Hirsch, M; Lederman, MM; Lietman, P; Pettinelli, CP; Richman, DD; Spector, SA1
Demeter, LM; Dexter, A; Dolin, R; Gerondelis, P; Morse, G; Nawaz, T; Reichman, RC1
Bartlett, JA; Cohen, OJ; Graziosi, C; Holodniy, M; Lalezari, J; Niu, M; Pantaleo, G; Pavlakis, GN; Schnittman, S; Steigbigel, RT1
Domanski, MJ; Egan, D; Follmann, DA; Pizzo, PA; Scalise, PP; Sloas, MM; Tucker, EE1
Darbyshire, J1
Gunnarsson, G; Hammer, SM1
Arasteh, K; Haase, W; Jablonowski, H; Ruf, B; Schomaker, U; Schrappe, M; Staszewski, S; Stellbrink, HJ; Stoehr, A; von Eisenhart Rothe, B1
Hoernle, EH; Reid, TE1
Cameron, W; Gallicano, K; Garber, G; Pakuts, A; Sahai, J1
Brouwers, P; Crowley, JS; Heyes, MP; Katz, DA; Kleiner, DE; Pizzo, PA; Saito, K; Sei, S; Stewart, SK1
Aperia, K; Cox, S; Palmer, S; Wahren, B1
Chokekuchai, S; Gao, WY; Johns, DG; Mitsuya, H1
Back, D; Barry, M; Giaquinto, C; Gibb, D; Nokes, L; Ormesher, S; Seefried, M1
Beaulieu, R; Cameron, B; Dunkle, L; Gill, J; Montaner, JS; Raboud, J; Rachlis, A; Salomon, H; Schechter, MT; Smaldone, L; Tsoukas, C; Wainberg, MA1
Bechtel, LJ; Chow, YK; D'Aquila, RT; Eron, JJ; Hirsch, MS; Kaplan, JC; Merrill, DP1
Rennie, J1
Kamali, F1
Campbell, TB; D'Aquila, RT; Eron, JJ; Kuritzkes, DR; Tarpley, WG; Young, RK1
Cohen, J1
Byrnes, VW; Condra, JH; Emini, EA; Gotlib, L; Graham, DJ; Schleif, WA1
Albert, J; Cox, SW; Ljungdahl-Ståhle, E; Wahren, B1
Hansen, JE; Mathiesen, LR; Nielsen, C; Nielsen, JO; Sørensen, AM1
Caliendo, AM; Chow, YK; Cooley, TP; D'Aquila, RT; Devore, KM; Eron, JJ; Hirsch, MS; Kaplan, JC; Liebman, HA; Videler, J1
Kellam, P; Kemp, SD; Larder, BA1
Allen, LB; Buckheit, RW; Decker, WD; Germany-Decker, J; Hollingshead, MG; McMahon, JB; Ross, LJ; Shannon, WM; Westbrook, L; White, EL1
Besemer, D; Fong, SJ; Hoo, B; Irvine, B; Kern, DG; Pachl, C; Sheridan, PJ; Stempien, M; Todd, JA; Yeghiazarian, T1
Bagnarelli, P; Clementi, M; Manzin, A; Menzo, S; Paolucci, S; Petroni, S; Sampaolesi, R; Scalise, G; Valenza, A; Varaldo, PE1
Anderson, BD; Kojima, E; Mitsuya, H; Shirasaka, T; Yarchoan, R1
Atwood, SM; Cummins, TJ; Dewhurst, S; Frenkel, LM; Wagner, LE1
Aboulker, JP; Darbyshire, JH; Debré, M; Giaquinto, C; Gibb, DM; Martinez, M; Tudor-Williams, G1
Baseler, MW; Foli, A; Saville, MW; Yarchoan, R1
Baughman, WL; Nosbisch, C; Pereira, CM; Unadkat, JD1
Amato, DA; Beltangady, M; Brown, MJ; Cross, AP; Dolin, R; Fischl, MA; Hardy, WD; Hirsch, MS; Liou, SH; Pettinelli, C1
Amato, DA; DeGruttola, V; Eyster, ME; Gjerset, GF; Ho, M; Kessler, CM; LoFaro, ML; Parenti, DM; Ragni, MV; Van Der Horst, C1
Lissen, E1
Boyer, E; Dong, H; Eastman, S; Holodniy, M; Kolberg, J; Margolis, D; Mole, L; Moss, J; Urdea, M1
Anderson, BD; Broder, S; Chokekijchai, S; Kojima, E; Mitsuya, H; Shirasaka, T; Steinberg, SM; Yarchoan, R1
Broder, S; Mitsuya, H; Nguyen, BY; Pluda, JM; Venzon, DJ; Wyvill, KM; Yarchoan, R1
Brown, T; Dancis, J; Esterman, AL; Rosenberg, C1
Faye, M; Michel, P; Sarthou, JL; Toure Balde, A1
Khoo, SH; Wilkins, EG1
Kitamura, T; Kunisada, T; Müller, WE; Ushijima, H1
Hsieh, YH; Velasco-Hernandez, JX1
Capparelli, EV; Connor, JD; Wu, LR1
Carroll, R; Holodniy, M; Margolis, D; Mole, L; Todd, J1
Birch, NJ; Gaines, H; Gallicchio, VS; Hughes, NK; Kirk, PR; Scott, KW; Tse, KF1
Hamby, RL; Henderson, GI; Perez, AB; Schenken, RS; Schenker, S; Yang, Y1
Back, DJ; Barry, MG; Veal, GJ; Wild, MJ1
Krasinski, K1
Spector, SA1
Abrams, DI1
Dormont, J1
Coombs, RW; DeGruttola, V; Fiscus, SA; Gupta, P; Katzenstein, DA; Katzman, M; LoFaro, ML; Meyer, WA; Ragni, MV; Reichelderfer, PS1
Machado, SG; Robinson, GA1
Coombs, RW; Crumpacker, CS; D'Aquila, RT; DeGruttola, V; Japour, AJ; Johnson, VA; Kahn, JO; Kuritzkes, DR; Reichelderfer, PS; Richman, DD; Welles, SL1
Dudley, MN1
Rowe, PM1
Baumberger, C; Hirschel, B; Kaiser, L; Perrin, LH; Yerly, S1
Albert, J; Apéria, K; Cox, SW; Wahren, B1
Debaisieux, L; Delforge, ML; Farber, CM; Liesnard, C; Tchetcheroff, M; Van Vooren, JP1
Carpenter, CC; Cobbs, CG; Holmes, KK; Sande, MA; Sanford, JP1
Houston, SC; Ostashewski, PM; Robertson, JA1
Klein, HG; Kumar, P; Merritt, S; Sacher, R; Sloand, E1
Agbaria, R; Brawley, OW; Lietzau, JA; Mitsuya, H; Nguyen, BY; Pluda, JM; Saville, MW; Steinberg, SM; Wyvill, KM; Yarchoan, R1
Lancaster, DJ; Lancaster, LL1
Bernstein, BM; Berry, A; Brand, J; Brown, MJ; Crane, L; Cross, A; Dunkle, LM; Frank, I; Green, SL; Gugliotti, R; Ingraham, P; MacArthur, RD; Morey, GE; Pachucki, CT; Patterson, TF; Pavia, AT; Peterson, D; Peterson, EA; Pollard, R; Ramirez-Ronda, CH; Remick, SC; Rios, A; Schindzielorz, AH; Smaldone, L; Spruance, SL; Sweet, DE; Thompson, M1
Bubp, J; Israelski, D; Katzenstein, DA; Merigan, TC; Winger, E; Winters, M1
Abrams, DI; Crane, LR; Goldman, AI; Grodesky, M; Kornegay, S; Korvick, JA; Launer, C; Muth, K; Neaton, JD; Wakefield, S1
Balis, FM; Brouwers, P; Farley, M; Goldsmith, JC; Husson, RN; Kovacs, A; Lewis, LL; Mueller, BU; Ono, J; Woods, L1
Bagnarelli, P; Clementi, M; Manzin, A; Menzo, S; Scalise, G; Valenza, A; Varaldo, PE1
Grange, JM; Hamedi-Sangsari, F; Malley, SD; Vila, JR2
Frost, SD; McLean, AR1
Arts, EJ; Wainberg, MA1
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Perronne, C1
Flexner, C; Gandhi, R1
Alesse, E; Boschini, A; De Simone, C; Famularo, G; Lucci, L; Marcellini, S; Moretti, S; Santini, G; Trinchieri, V1
Aldamiz-Etxebarría, M; Andonegui Navarro, J1
Brandi, G; Casabianca, A; Cerasi, A; Chiarantini, L; Fraternale, A; Magnani, M; Orlandi, C1
Fan, B; Stewart, JT1
Brandi, G; Casabianca, A; Chiarantini, L; Fraternale, A; Magnani, M; Orlandi, C; Silvestri, G1
Bettendorf, DM; Christopherson, C; D'Aquila, RT; Hammer, SM; Katzenstein, DA; Lathey, JL; Tierney, C1
Baldanti, F; Galloni, D; Gerna, G; Lilleri, D; Piccinini, G; Seminari, E1
Graziadei, IW; Koch, RO; Maier, H; Romani, N; Vogel, W; Zangerle, R1
Campos, SB; de Araujo, M; Magaldi, AJ; Rienzo, M; Seguro, AC; Seguro, FS1
Aboulker, JP; Brun-Vézinet, F; Descamps, D; Flandre, P; Izopet, J; Joly, V; Meiffrédy, V; Tamalet, C1
Oka, S; Teruya, K1
Bacheler, L; Erickson-Viitanen, S; Gallagher, K; Garber, S; Geleziunas, R; Otto, MJ; Schinazi, RF; Shi, G; Wu, JT; Zhang, H1
Andron, L; Asmuth, DM; Grady, JJ; Green, S; McKinsey, DS; Pollard, RB; Rossero, R1
Harada, S; Kavlick, MF; Kosalaraksa, P; Matsumi, S; Mitsuya, H; Tsang, H1
Bachiller Luque, P; de Luis Román, DA; Eiros Bouza, JM; Ortega Lafont, M; Ortiz de Lejarazu, R1
Das, P1
Lin, DY; Ying, Z1
Chuenyam, T; Cooper, D; Emery, S; Lange, J; Phanuphak, P; Ruxrungtham, K; Sirivichayakul, S; Techasathit, W; Ubolyam, S; Ungsedhapand, C1
Daniels, MJ; Robins, JM; Scharfstein, DO1
Barber, RE; Lonergan, JT; Mathews, WC1
Becker, MI; D'Aquila, RT; De Gruttola, V; Delapenha, R; Dubé, MP; Fischl, MA; Gedeon, L; Hirsch, MS; Merigan, TC; Murphy, RL; Pettinelli, C; Pollard, RB; Robbins, GK; Shafer, RW; Smeaton, LM; Snyder, SW; van der Horst, C; Vella, S1
D'Aquila, RT; De Gruttola, V; Gripshover, BM; Haubrich, R; Hirsch, MS; Johnson, VA; Kaul, P; Martinez, AI; McCarty, SD; Merigan, TC; Morse, GD; Nokta, MA; Robbins, GK; Shafer, RW; Smeaton, LM; Snyder, SW; Swingle, M; Vella, S1
Albert, J; Antonsson, L; Fenyö, EM; Karlsson, A; Karlsson, I; Leitner, T; Olde, B; Owman, C; Shi, Y1
Casula, M; de Ronde, A; Goudsmit, J; Lange, JM; Reiss, P; Weverling, GJ1
Baker, CJ; Colgrove, RC; Englund, JA; McKinney, R; Nikolic-Djokic, D; Palumbo, P; Raskino, C; Ross, LL; Vavro, C1
Bishop, JB; Tice, RR; Witt, KL; Wolfe, GW2
Agher, R; Ait-Mohand, H; Bricaire, F; Calvez, V; Costagliola, D; Duvivier, C; Ghosn, J; Katlama, C; Marcelin, AG; Myrto, A; Peytavin, G; Schneider, L1
Boyle, BA1
Burzykowski, T; Geys, H; Molenberghs, G; Tibaldi, F1
Babiker, AG; Dunn, DT; Goodall, RL1
Cardiello, P; Cooper, DA; Emery, S; Juengprasert, N; Kroon, ED; Lange, JM; Phanuphak, P; Ratanasuwan, W; Ruxrungtham, K; Siangphoe, U; Srasuebkul, P; Tongtalung, M; Ubolyam, S; Ungsedhapand, C1
Beland, FA; Bishop, ME; Dobrovolsky, VN; Heflich, RH; Shaddock, JG; Von Tungeln, LS1
Bates, M; Chappey, C; Clair, MS; Fisher, R; Lanier, ER; Parkin, N; Ross, L; Tisdale, M1
Rosa, U; Sepkowitz, D; Smith, PR; Tripuraneni, NS; Weedon, J1
Artuch, R; Fortuny, C; Jimenez, R; Muñoz-Almagro, C; Noguera, A; Pou, J; Sanchez, E; Vilaseca, MA1
Auclair, M; Capeau, J; Caron, M; Kornprobst, M; Lagathu, C; Lombès, A; Walker, UA1
Aarnoutse, RE; Burger, DM; Verweij-van Wissen, CP1
Ambu, S; Bartolozzi, D; Boddi, V; Farese, A; Giuntini, R; Leoncini, F; Martinelli, C1
Fahey, JL; Grossberg, SE; Johnston, DM; Kagan, J; Mildvan, D; Schock, BR; Spritzler, J1
Cossarizza, A; Ferraresi, R; Galluzzi, L; Mussini, C; Nasi, M; Pinti, M; Prada, N; Salomoni, P; Troiano, L1
Abraira, V; Antela, A; Casado, JL; Dronda, F; Gutiérrez, C; López, D; Moreno, A; Moreno, S; Pérez-Elías, MJ; Rodríguez, MA1
Baker, SG; Fitzmaurice, GM; Freedman, LS; Kramer, BS1
Britto, P; Capparelli, E; Cowles, MK; Fowler, MG; Husson, RN; Kovacs, A; McIntosh, K; Moye, J; Pitt, J; Rathore, MH1
Götte, M; Kuritzkes, DR; Liang, F; Miranda, LR1
Chêuc, G; Cotte, L; Debord, T; Decazes, JM; Ferchal, F; Journot, V; Madelaine, I; Molina, JM; Pellegrin, I; Rancinan, C; Sombardier, MN1
Campanini, A; Cancellieri, C; Marani, M; Mastroianni, A; Vicini, C1
Lewis, W1
Alston-Smith, BL; Dubé, MP; Kitch, DW; Mulligan, K; Parker, RA1
Alhassoon, OM; Brown, GG; Ellis, RJ; Gonzalez, R; Grant, I; Letendre, S; McCutchan, JA; Patterson, TL; Schweinsburg, BC; Taylor, MJ; Videen, JS1
Engels, JW; Lazrek, HB; Rochdi, A; Taourirte, M; Vasseur, JJ1
Bautista-Arredondo, S; Bertozzi, SM; Mane, A1
Ballardin, M; Barale, R; Kotwal, GJ; Scarpato, R1
Abrams, EJ; Gvetadze, R; Kline, MW; Rivadeneira, E; Weidle, PJ1
Bampi, C; Bibillo, A; Darlix, JL; Divita, G; Gorelick, RJ; Le Grice, SF; Wendeler, M1
Collier, AC; Lockhart, DW; Marra, CM; Rees, TS; Schouten, JT1
Kiseleva, IaIu; Pliasunova, OA; Pokrovskaia, NV; Pokrovskiĭ, AG1
Barberá Farré, JR; Beato Pérez, JL; Cuadra García-Tenorio, F; Geijo Martínez, MP; Maciá Martínez, MA; Marcos Sánchez, F; Martínez Alfaro, E; Moreno Mendaña, JM; Rodríguez Zapata, M; Sanz Moreno, J; Sanz Sanz, J; Solera Santos, J1
Balestre, E; Boucher, S; Capdepont, S; Dabis, F; Dupon, M; Fleury, H; Masquelier, B; Thiébaut, R1
Gray, G; Jivkov, B; Ledeine, JM; McIntyre, J; Reynolds, L; Schnittman, S; Violari, A1
Bacheler, L; Koontz, D; Mellors, JW; Parikh, UM1
Alvarez, ML; Cihlar, T; Cordobilla, B; Domingo, JC; Domingo, P; Giralt, M; Guallar, J; López-Dupla, M; Sánchez de la Rosa, R; Saumoy, M; Torres, F; Vidal, F; Villarroya, F1
Engchanil, C; Kosalaraksa, P; Lulitanond, V; Lumbiganon, P; Pongjunyakul, P; Suwan-apichon, O; Thuennadee, R; Tungsawad, S1
Kilby, M; McDonald, JM; Pan, G1
Amellal, B; Calvez, V; Castro, ND; Chêne, G; Cotte, L; Gourlain, K; Journot, V; Molina, JM; Palmer, P; Pédrono, G; Rancinan, C1
López, G; Omiste, T; Ramos, C; Ruiz, M1
Teruya, K1
Dubé, MP; Grinspoon, SK; Mulligan, K; Parker, RA; Robbins, GK; Roubenoff, R; Tebas, P1
Johnston, E; Kassaye, SG; Katzenstein, DA; Shulman, NS; Winters, MA1
Abdoulaye, D; André, C; André, E; Bernard, L; Sandrine, PF; Sylvie, A1
Dubé, MP; Grinspoon, SK; Komarow, L; Mulligan, K; Parker, RA; Robbins, GK; Roubenoff, R; Tebas, P1
Bussmann, H; DeGruttola, V; Essex, M; Gaseitsiwe, S; Marlink, RG; Moyo, S; Musonda, R; Novitsky, V; Thomas, A; Van Widenfelt, E; Wester, CW1
Enejosa, J; Hinkle, J; Kearney, BP; Ramanathan, S; Shen, G1
Doerries, R; Drechsler, H; Gass, A; Hardmeier, M; Kuhle, J; Mehling, M; Ruegg, S1
de Andrade, HH; de Castro Pereira, K; Guimarães, NN; Lehmann, M; Silva Cunha, K1
Arenas-Pinto, A; Bhaskaran, K; Dunn, D; Weller, IV1
Basseila, GB; Bokilo, AD; Dokekias, AE; Galiba, FO; Malanda, F; Nsitou, MB; Ntsimba, P1
Ahmadou Ahidjo, B; Becker, P; Dusé, AG; Marais, E; Veale, R1
Cao, YL; Guo, Y1
Braude, J; Galambos, MR; Joelson, D; Johnson, M; Rubin, RA; Saifee, S; Sellers, M; Shrestha, R1
Bentata, M; Chêne, G; Collin, F; Garré, M; Goujard, C; Lafaurie, M; Leport, C; Levy, Y; Molina, JM1
Angels Ribas, M; Asensi, V; Berenguer, J; Domingo, P; Gimeno, JL; González, J; Miralles, P; Pedrol, E; Pérez-Molina, JA; Ribera, E; Santamaría, JM; Santos, J; Terrón, JA1
Berrisford, AE; Boulle, AM; Jaspan, HB1
Antonelli, A; Casabianca, A; Fraternale, A; Magnani, M; Orlandi, C; Paoletti, MF; Pierigè, F; Rossi, L; Schiavano, GF; Serafini, S; Sfara, C1
Ishikawa, H; Kaneko, S; Katayama, M; Matsuda, Y; Miyaji, K; Suzuki, K; Takamatsu, K1
Afonso, AO; Cunha, SM; Lemey, P; Machado, ES; Nissley, DV; Oliveira, RH; Soares, MA1
Bouic, PJ; Pretorius, E1
Bussmann, H; Degruttola, V; Essex, M; Gaolathe, T; Makhema, J; Marlink, RG; Mawoko, N; Mine, M; Moffat, H; Moyo, S; Musonda, R; Muzenda, T; Ndwapi, N; Novitsky, V; Okezie, R; Thomas, A; Wester, CW; Widenfelt, E1
Carter, MM; Hardy, AW; Kajon, AE; McCash, CL; Olivero, OA; Poirier, MC; Shearer, GM; Swenberg, JA; Torres, SM; Upton, PB; Walker, DM; Walker, VE1
Heckl-Ostreicher, B; Lebrecht, D; Reuss, FU; Venhoff, AC; Venhoff, N; Walker, UA; Wehr, R1
Fox, MP; Ive, P; Long, L; Maskew, M; Sanne, I1
Cooper, V; Fisher, M; Gellaitry, G; Horne, R; Lange, AC; Vrijens, B; White, D1
Achalapong, J; Ariyadej, S; Chotivanich, N; Collins, IJ; Cressey, TR; Frenkel, LM; Hemvuttiphan, J; Jarupanich, T; Jourdain, G; Kanchana, S; Kanjanasing, A; Kengsakul, K; Koetsawang, S; Lallemant, M; Le Coeur, S; Liampongsabuddhi, P; McIntosh, K; Ngo-Giang-Huong, N; Pornkitprasarn, W; Ratanakosol, J; Sabsanong, P; Sittipiyasakul, V; Sukhumanant, T; Traisaithit, P; Van Dyke, RB; Wannapira, W; Winiyakul, N1
Cotton, MF; Rabie, H; van Zyl, GU1
Fitzmaurice, GM; Ibrahim, JG; Lipsitz, SR; Molenberghs, G; Sinha, D; Troxel, AB1
Aguiar, CV; Braga Neto, MB; Brito, GA; Guerrant, RL; Lima, AA; Maciel, JG; Oliveira, BM; Oriá, RB; Sevilleja, JE; Warren, CA1
Cook, A; Divi, RL; Einem, TL; Fletcher, SL; Harbaugh, JW; Harbaugh, SW; Kuo, MM; Nagashima, K; Poirier, MC; Shockley, ME; St Claire, MC1
Feng, Y; Huang, J; Huang, Y; Liao, L; Liu, S; Ma, L; Qu, S; Shao, Y; Sun, J; Xing, H; Yu, X; Yuan, L1
Dhlomo, S; Emery, S; Grandits, G; Khabo, P; Khanyile, T; Komati, S; Magongoa, D; Naidoo, LC; Neaton, JD; Polis, M; Qolohle, D; Ratsela, A1
Delaporte, E; Diouf, A; Etard, JF; Girard, PM; Landman, R; Laurent, C; Molinari, N; Ndoye, I; Ngom Guèye, NF; Sow, PS; Tchatchueng Mbougua, JB1
Du, L; Jin, Y; Li, M; Tong, L; Xin, R1
Arenas-Pinto, A; Bolhaar, M; Bradman, N; Ekong, R; Grant, A; Ingram, C; Karstaedt, A; Reiss, P; Telisinghe, L; Weber, R; Weller, I1
Aschacher, T; Bergmann, M; Bernhard, D; Holzmann, K; Käser, L; Sampl, S; Spittler, A1
Lovett, ST; Seier, T; Zeiger, DM; Zilberberg, G1
Côté, HC; Hukezalie, KR; Thumati, NR; Wong, JM1
Cunha, KS; de Andrade, HH; Dihl, RR; Guimarães, NN; Lehmann, M; Silva, CJ1
Gabrielian, A; Holland, GN; Kukuyev, A; MacCumber, MM; Mitsuyasu, R; Sarraf, D1
Campbell, GR; Pallack, ZT; Spector, SA1
Chen, D; Chen, X; Ding, W; Gao, Z; Jin, R; Qiao, L; Song, F; Yang, S; Zhang, Y1
Gibbons, AT; Liu, Y; Mitchell, JB; Nguyen, P; Poirier, MC; Shim, E1
Berendes, S; Campbell, TB; Cardoso, SW; Christian, P; Gupta, A; Gupte, N; Kanyama, C; Lama, JR; Mwelase, N; Pillay, S; Riviere, C; Samaneka, W; Semba, RD; Shivakoti, R; Sugandhavesa, P; Tang, AM; Yang, WT1
Gilks, CF; Kikaire, B; Kiwuwa-Muyingo, S; Levin, JB; Mambule, I; Musana, H; Musoro, G; Walker, AS1
Brul, S; de Boer, R; De Vos, WH; Manders, EM; Smith, RL; van der Spek, H1
Chen, D; Chen, J; Guo, H; Liang, Q; Qiao, L; Wang, B; Wu, J; Xu, B; Yang, S; Zhang, H; Zhang, Y1
Avi, R; Huik, K; Jõgeda, EL; Kallas, E; Karki, T; Lutsar, I; Margus, T; Pauskar, M1
Arnold, E; Das, K; Martinez, SE1
Abad-Carrillo, MA; Álvarez-Ríos, AI; Bernal-Morell, E; Genebat, M; González-García, J; Herrero-Fernández, I; Leal, M; Montero, M; Pacheco, YM; Pulido, F; Rosado-Sánchez, I; Ruiz-Mateos, E; Vidal, F1
Blanche, S; Clavel, J; Dollfus, C; Faye, A; Goujon, S; Hleyhel, M; Mandelbrot, L; Sibiude, J; Tubiana, R; Warszawski, J1
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Ge, Z; Mashiach, D; Miller, JH; Shin, J; Singh, S; Yaramada, L1

Reviews

103 review(s) available for zidovudine and didanosine

ArticleYear
Natural product-based anti-HIV drug discovery and development facilitated by the NCI developmental therapeutics program.
    Journal of natural products, 2001, Volume: 64, Issue:2

    Topics: Amino Acid Sequence; Anti-HIV Agents; HIV-1; Models, Biological; Models, Chemical; Molecular Sequence Data; National Institutes of Health (U.S.); Retrospective Studies; United States; Virus Replication

2001
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Polypharmacology in HIV inhibition: can a drug with simultaneous action against two relevant targets be an alternative to combination therapy?
    European journal of medicinal chemistry, 2018, Apr-25, Volume: 150

    Topics: Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Drug Therapy, Combination; HIV; Humans; Microbial Sensitivity Tests; Molecular Structure; Polypharmacology

2018
[New therapeutic trends in AIDS].
    La Clinica terapeutica, 1992, Volume: 140, Issue:2

    Topics: Acquired Immunodeficiency Syndrome; Adult; Antiviral Agents; Deoxyadenosines; Didanosine; Dideoxynucleosides; Humans; Poly I-C; Poly U; Randomized Controlled Trials as Topic; Ribavirin; RNA, Double-Stranded; Zalcitabine; Zidovudine

1992
New developments in antiretroviral drug therapy for HIV infection.
    AIDS clinical review, 1992

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Didanosine; Drug Combinations; Drug Therapy, Combination; Gene Products, tat; HIV Infections; HIV-1; Humans; Protease Inhibitors; tat Gene Products, Human Immunodeficiency Virus; Zalcitabine; Zidovudine

1992
Anti-human immunodeficiency virus therapeutics: now and the future.
    Seminars in liver disease, 1992, Volume: 12, Issue:2

    Topics: Acquired Immunodeficiency Syndrome; Didanosine; Dideoxynucleosides; HIV; HIV-1; Humans; Trichosanthin; Zalcitabine; Zidovudine

1992
The use of nucleoside analogues in the treatment of HIV-infected children.
    AIDS research and human retroviruses, 1992, Volume: 8, Issue:6

    Topics: Child; Child, Preschool; Didanosine; Drug Therapy, Combination; HIV Infections; Humans; Infant; Infant, Newborn; Zalcitabine; Zidovudine

1992
Treatment of HIV infection: the antiretroviral nucleoside analogues. Nucleoside analogues: combination therapy.
    Hospital practice (Office ed.), 1992, Volume: 27 Suppl 2

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Didanosine; Drug Evaluation; Drug Resistance, Microbial; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Zalcitabine; Zidovudine

1992
Treatment of HIV infection: the antiretroviral nucleoside analogues. Nucleoside analogues: adverse effects.
    Hospital practice (Office ed.), 1992, Volume: 27 Suppl 2

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Didanosine; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Zalcitabine; Zidovudine

1992
Treatment of HIV infection: the antiretroviral nucleoside analogues. Nucleoside analogues: monotherapy.
    Hospital practice (Office ed.), 1992, Volume: 27 Suppl 2

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Didanosine; Drug Resistance, Microbial; HIV Infections; HIV-1; Humans; Time Factors; Zalcitabine; Zidovudine

1992
HIV disease: therapy, related systemic and oral conditions--an update.
    Compendium (Newtown, Pa.), 1992, Volume: 13, Issue:4

    Topics: Acquired Immunodeficiency Syndrome; Bacterial Infections; Didanosine; HIV Infections; Humans; Mouth Diseases; Mycoses; Sarcoma, Kaposi; Virus Diseases; Zalcitabine; Zidovudine

1992
Primary care for HIV infection.
    Hospital practice (Office ed.), 1992, Feb-28, Volume: 27, Issue:2A

    Topics: CD4-Positive T-Lymphocytes; Clinical Protocols; Clinical Trials as Topic; Didanosine; Drug Monitoring; HIV Infections; HIV-1; Humans; Immunization; Leukocyte Count; Pneumonia, Pneumocystis; Primary Health Care; Sex Counseling; Zidovudine

1992
Didanosine.
    The Annals of pharmacotherapy, 1992, Volume: 26, Issue:5

    Topics: Acquired Immunodeficiency Syndrome; Adult; CD4-Positive T-Lymphocytes; Child; Child, Preschool; Clinical Trials as Topic; Didanosine; Drug Evaluation; Drug Interactions; Female; Humans; Leukocyte Count; Male; Time Factors; Zidovudine

1992
Current status of therapy for human immunodeficiency virus type 1.
    Current opinion in immunology, 1992, Volume: 4, Issue:4

    Topics: CD4-CD8 Ratio; CD4-Positive T-Lymphocytes; Didanosine; Drug Resistance; HIV Infections; HIV Seropositivity; HIV-1; Humans; T-Lymphocytes, Helper-Inducer; Zalcitabine; Zidovudine

1992
[Anti-HIV treatment, today and in the near future].
    Nederlands tijdschrift voor geneeskunde, 1992, Aug-01, Volume: 136, Issue:31

    Topics: Antiviral Agents; Didanosine; Dideoxynucleosides; DNA, Viral; Drug Therapy, Combination; HIV Infections; Humans; Reverse Transcriptase Inhibitors; Stavudine; Transcription, Genetic; Zalcitabine; Zidovudine

1992
[Treatments of human immunodeficiency virus infection. Current developments].
    Annales de medecine interne, 1991, Volume: 142, Issue:3

    Topics: Acquired Immunodeficiency Syndrome; Didanosine; HIV; HIV Infections; Humans; Zalcitabine; Zidovudine

1991
New developments in dideoxynucleoside antiretroviral therapy for HIV infection.
    AIDS clinical review, 1991

    Topics: Acquired Immunodeficiency Syndrome; Didanosine; Dideoxynucleosides; HIV Infections; Humans; Zalcitabine; Zidovudine

1991
HIV/AIDS pathogenesis and treatment: new twists and turns.
    Current opinion in immunology, 1991, Volume: 3, Issue:4

    Topics: Acquired Immunodeficiency Syndrome; CD4-Positive T-Lymphocytes; Didanosine; Humans; Lymphocyte Depletion; Trichosanthin; Zalcitabine; Zidovudine

1991
Chemotherapy of human immunodeficiency virus infections: current practice and future prospects.
    The Journal of infectious diseases, 1990, Volume: 161, Issue:5

    Topics: Animals; Antiviral Agents; Didanosine; DNA Nucleotidyltransferases; DNA Replication; Drug Therapy, Combination; Endopeptidases; HIV Infections; HIV-1; Humans; Integrases; RNA-Directed DNA Polymerase; Virus Replication; Zalcitabine; Zidovudine

1990
Targeted therapy of human immunodeficiency virus-related disease.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 1991, Volume: 5, Issue:10

    Topics: Acquired Immunodeficiency Syndrome; Adenine; Antiviral Agents; CD4 Antigens; Didanosine; Dideoxynucleosides; Dipyridamole; Drug Synergism; Gene Expression Regulation, Viral; Genes, nef; Genes, rev; Genes, tat; HIV; HIV Protease; Interferon Type I; Organophosphonates; RNA-Directed DNA Polymerase; Stavudine; Transcription, Genetic; Zalcitabine; Zidovudine

1991
Anti-retroviral therapy of human immunodeficiency virus infection: current strategies and challenges for the future.
    Blood, 1991, Aug-15, Volume: 78, Issue:4

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Didanosine; Drug Resistance; HIV; HIV Infections; Humans; Lymphoma, Non-Hodgkin; Retroviridae; Reverse Transcriptase Inhibitors; T-Lymphocytes, Helper-Inducer; Virus Replication; Zalcitabine; Zidovudine

1991
Zidovudine and other reverse transcriptase inhibitors in the management of human immunodeficiency virus-related disease.
    Pharmacotherapy, 1991, Volume: 11, Issue:6

    Topics: Acquired Immunodeficiency Syndrome; Adult; Antiviral Agents; Child; Didanosine; Female; Foscarnet; HIV Infections; Humans; Phosphonoacetic Acid; Pregnancy; Reverse Transcriptase Inhibitors; Zalcitabine; Zidovudine

1991
Preclinical evaluation of human hematolymphoid function in the SCID-hu mouse.
    Immunological reviews, 1991, Volume: 124

    Topics: Acquired Immunodeficiency Syndrome; Animals; Bone Marrow Transplantation; Didanosine; Hematopoiesis; HIV; Humans; Liver Transplantation; Lymph Nodes; Mice; Mice, SCID; Models, Biological; Thymus Gland; Transplantation, Heterologous; Zidovudine

1991
Treatment of AIDS with combinations of antiretroviral agents.
    The American journal of medicine, 1991, Apr-10, Volume: 90, Issue:4A

    Topics: Acquired Immunodeficiency Syndrome; Clinical Trials as Topic; Didanosine; Drug Therapy, Combination; Humans; Interferon Type I; Recombinant Proteins; Zalcitabine; Zidovudine

1991
Update on reverse transcriptase inhibitors in HIV disease.
    Israel journal of medical sciences, 1993, Volume: 29, Issue:10 Suppl

    Topics: Acquired Immunodeficiency Syndrome; Clinical Trials as Topic; Didanosine; Humans; Prognosis; Reverse Transcriptase Inhibitors; Risk Factors; Zalcitabine; Zidovudine

1993
[Reverse transcriptase inhibitors as anti-HIV agents].
    Nihon rinsho. Japanese journal of clinical medicine, 1993, Volume: 51 Suppl

    Topics: Amino Acid Sequence; Antiviral Agents; Didanosine; Drug Resistance, Microbial; HIV Reverse Transcriptase; HIV-1; Humans; Mutation; Protein Conformation; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Zalcitabine; Zidovudine

1993
Resistance of human immunodeficiency virus type 1 to antiretroviral agents: a review.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1994, Volume: 18, Issue:2

    Topics: Antiviral Agents; Didanosine; Drug Resistance, Microbial; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Microbial Sensitivity Tests; Reverse Transcriptase Inhibitors; Zalcitabine; Zidovudine

1994
Pharmacologic therapy for human immunodeficiency virus infection: a review.
    The American journal of the medical sciences, 1994, Volume: 307, Issue:5

    Topics: Antiviral Agents; Didanosine; Drug Resistance, Microbial; HIV Infections; HIV Protease Inhibitors; Humans; Reverse Transcriptase Inhibitors; Stavudine; Structure-Activity Relationship; Zidovudine

1994
Combination therapy for infection due to human immunodeficiency virus type 1.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1994, Volume: 18, Issue:4

    Topics: Acyclovir; Antiviral Agents; CD4 Antigens; Clinical Trials as Topic; Combined Modality Therapy; Didanosine; Drug Therapy, Combination; Foscarnet; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; In Vitro Techniques; Interferon alpha-2; Interferon-alpha; Recombinant Proteins; Reverse Transcriptase Inhibitors; Zalcitabine; Zidovudine

1994
Survival effects of ZDV, ddI, and ddC in patients with CD4 < or = 50 cells/mm3.
    Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association, 1995, Volume: 10 Suppl 2

    Topics: Antiviral Agents; CD4 Lymphocyte Count; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Didanosine; Double-Blind Method; HIV Infections; Humans; Randomized Controlled Trials as Topic; Risk Assessment; Survival Analysis; Zalcitabine; Zidovudine

1995
Mitochondrial toxicity of antiviral drugs.
    Nature medicine, 1995, Volume: 1, Issue:5

    Topics: Acquired Immunodeficiency Syndrome; Animals; Antiviral Agents; Arabinofuranosyluracil; Didanosine; DNA-Directed DNA Polymerase; DNA, Mitochondrial; Humans; Mitochondria; Zalcitabine; Zidovudine

1995
Pharmacokinetic optimisation of antiretroviral therapy in patients with HIV infection.
    Clinical pharmacokinetics, 1995, Volume: 29, Issue:1

    Topics: Aging; Antineoplastic Agents; Antiviral Agents; Didanosine; Drug Interactions; Guidelines as Topic; HIV Infections; Humans; Phosphorylation; Racial Groups; Sex Characteristics; Stavudine; Zalcitabine; Zidovudine

1995
An approach to antiretroviral treatment of HIV disease. Nucleoside monotherapy.
    Hospital practice (1995), 1995, Volume: 30 Suppl 1

    Topics: Antiviral Agents; Didanosine; HIV Infections; HIV-1; Humans; Lamivudine; Nucleosides; Stavudine; Zalcitabine; Zidovudine

1995
Human immunodeficiency virus infection in children.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 1995, May-01, Volume: 52, Issue:9

    Topics: Adolescent; AIDS-Related Opportunistic Infections; Child; Child, Preschool; Dapsone; Didanosine; Drug Interactions; Drug Therapy, Combination; Female; HIV Infections; Humans; Male; Pentamidine; Pneumonia, Pneumocystis; Pregnancy; Pregnancy Complications, Infectious; Recurrence; Stavudine; Trimethoprim, Sulfamethoxazole Drug Combination; Zalcitabine; Zidovudine

1995
Clinical pharmacology of zidovudine and other 2',3'-dideoxynucleoside analogues.
    The Clinical investigator, 1993, Volume: 71, Issue:5

    Topics: Acquired Immunodeficiency Syndrome; Adult; Child; Didanosine; Dideoxynucleosides; Drug Interactions; Drug Resistance, Microbial; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Interferons; Needlestick Injuries; Sarcoma, Kaposi; Zalcitabine; Zidovudine

1993
[Anti-HIV therapy (1987-1994): from nothing to confusion].
    Medicina clinica, 1995, Apr-01, Volume: 104, Issue:12

    Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Complex; Clinical Trials as Topic; Didanosine; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Time Factors; Zalcitabine; Zidovudine

1995
Controversies in anti-retroviral therapy of adults.
    The Journal of antimicrobial chemotherapy, 1995, Volume: 35, Issue:2

    Topics: Acquired Immunodeficiency Syndrome; Acyclovir; AIDS-Related Complex; AIDS-Related Opportunistic Infections; CD4 Lymphocyte Count; Didanosine; Drug Therapy, Combination; Drug Tolerance; HIV Infections; HIV-1; Humans; Zalcitabine; Zidovudine

1995
Therapy of pediatric AIDS.
    Current opinion in pediatrics, 1995, Volume: 7, Issue:2

    Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Opportunistic Infections; Child; Didanosine; Humans; Immunization, Passive; Infectious Disease Transmission, Vertical; Vaccination; Zidovudine

1995
Antiretroviral therapy for children.
    Acta paediatrica (Oslo, Norway : 1992). Supplement, 1994, Volume: 400

    Topics: Acquired Immunodeficiency Syndrome; Adult; Child; Clinical Trials as Topic; Controlled Clinical Trials as Topic; Didanosine; DNA, Viral; Drug Resistance, Microbial; HIV-1; Humans; Immunity, Cellular; Virus Replication; Zalcitabine; Zidovudine

1994
HIV therapy advances. Pediatric antiretroviral choices.
    AIDS (London, England), 1994, Volume: 8 Suppl 3

    Topics: Body Weight; Clinical Trials as Topic; Didanosine; Female; Growth; HIV Infections; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Pregnancy; Pregnancy Complications, Infectious; Treatment Failure; Zalcitabine; Zidovudine

1994
Future treatment strategies in HIV infection.
    AIDS (London, England), 1994, Volume: 8 Suppl 3

    Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Complex; Antiviral Agents; Biomarkers; CD4 Lymphocyte Count; Didanosine; Forecasting; HIV Infections; Humans; Zalcitabine; Zidovudine

1994
Nucleoside reverse transcriptase inhibitors and resistance of human immunodeficiency virus type 1.
    The Journal of infectious diseases, 1995, Volume: 171 Suppl 2

    Topics: Clinical Trials as Topic; Didanosine; Dideoxynucleosides; Drug Resistance; HIV Infections; HIV-1; Humans; Zidovudine

1995
Clinical pharmacokinetics of nucleoside antiretroviral agents.
    The Journal of infectious diseases, 1995, Volume: 171 Suppl 2

    Topics: Animals; Didanosine; Dideoxynucleosides; HIV Infections; Humans; Lamivudine; Stavudine; Zalcitabine; Zidovudine

1995
Antiretroviral therapy for adult HIV-infected patients. Recommendations from a state-of-the-art conference. National Institute of Allergy and Infectious Diseases State-of-the-Art Panel on Anti-Retroviral Therapy for Adult HIV-Infected Patients.
    JAMA, 1993, Dec-01, Volume: 270, Issue:21

    Topics: Adult; CD4-Positive T-Lymphocytes; Clinical Trials as Topic; Didanosine; Dideoxynucleosides; Drug Resistance; Guidelines as Topic; HIV Infections; Humans; Leukocyte Count; Zalcitabine; Zidovudine

1993
Management of antiretroviral drug therapy in human immunodeficiency virus infection.
    Critical reviews in clinical laboratory sciences, 1994, Volume: 31, Issue:2

    Topics: Acquired Immunodeficiency Syndrome; Didanosine; HIV-1; Humans; Retroviridae Infections; Zalcitabine; Zidovudine

1994
Antiretroviral therapy for human immunodeficiency virus infection: hope and despair.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 1994, Volume: 48, Issue:2

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Didanosine; Humans; In Vitro Techniques; Zalcitabine; Zidovudine

1994
[Antiretroviral therapy. Current status and perspectives].
    Der Internist, 1994, Volume: 35, Issue:10

    Topics: Antiviral Agents; CD4 Lymphocyte Count; Clinical Trials as Topic; Didanosine; Drug Therapy, Combination; HIV; HIV Infections; Humans; Stavudine; Zalcitabine; Zidovudine

1994
Adverse effects and drug interactions of clinical importance with antiviral drugs.
    Drug safety, 1994, Volume: 10, Issue:4

    Topics: Acyclovir; AIDS-Related Opportunistic Infections; Amantadine; Antiviral Agents; Didanosine; Drug Interactions; Foscarnet; Ganciclovir; Humans; Interferon-alpha; Ribavirin; Rimantadine; Vidarabine; Zalcitabine; Zidovudine

1994
Managing occupational risks in the dental office: HIV and the dental professional.
    Journal of the American Dental Association (1939), 1994, Volume: 125, Issue:7

    Topics: Blood-Borne Pathogens; Dental Staff; Didanosine; HIV Infections; HIV Seropositivity; Humans; Needlestick Injuries; Occupational Exposure; Risk Factors; Universal Precautions; Zidovudine

1994
Perspectives on the use of antiretroviral drugs in the treatment of HIV infection.
    Infectious disease clinics of North America, 1994, Volume: 8, Issue:2

    Topics: Didanosine; Dideoxynucleosides; Drug Administration Schedule; HIV Infections; Humans; Stavudine; Zalcitabine; Zidovudine

1994
Effect of HIV treatment on cognition, behavior, and emotion.
    The Psychiatric clinics of North America, 1994, Volume: 17, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Cognition Disorders; Cycloserine; Didanosine; Humans; Mental Disorders; Mood Disorders; Stavudine; Zidovudine

1994
[Therapy of HIV infection with nucleoside analogs].
    Zeitschrift fur Gastroenterologie, 1993, Volume: 31 Suppl 5

    Topics: Antiviral Agents; Didanosine; Drug Therapy, Combination; HIV; HIV Infections; Humans; Nucleosides; Zalcitabine; Zidovudine

1993
Pharmacodynamics of antiretroviral chemotherapy.
    Infection control and hospital epidemiology, 1993, Volume: 14, Issue:9

    Topics: Antiviral Agents; Biological Availability; CD4 Antigens; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Dextran Sulfate; Didanosine; HIV Core Protein p24; HIV Infections; Humans; T-Lymphocytes; Zidovudine

1993
[Dideoxynucleoside therapy in acquired immunodeficiency syndrome].
    Harefuah, 1993, Nov-01, Volume: 125, Issue:9

    Topics: Acquired Immunodeficiency Syndrome; Clinical Trials as Topic; Didanosine; Dideoxynucleosides; Humans; Zidovudine

1993
[What is known about the cellular and molecular pharmacodynamics of nucleosides?].
    Pathologie-biologie, 1993, Volume: 41, Issue:8 Pt 2

    Topics: Didanosine; Dideoxyadenosine; Dideoxynucleosides; DNA-Directed DNA Polymerase; Drug Resistance, Microbial; Hematopoietic Stem Cells; HIV-1; Humans; In Vitro Techniques; Zidovudine

1993
[Is resistance of human immunodeficiency viruses (HIV) to nucleoside analogs an indication for their combined use?].
    Pathologie-biologie, 1993, Volume: 41, Issue:8 Pt 2

    Topics: Acyclovir; Didanosine; Drug Synergism; Drug Therapy, Combination; Female; Foscarnet; HIV-1; Humans; In Vitro Techniques; Male; Ribavirin; Zalcitabine; Zidovudine

1993
Roundtable discussion: management issues in didanosine therapy.
    Journal of acquired immune deficiency syndromes, 1993, Volume: 6 Suppl 1

    Topics: Didanosine; Dose-Response Relationship, Drug; Health Personnel; HIV Infections; Humans; Occupational Exposure; Pancreatitis; Peripheral Nervous System Diseases; Zidovudine

1993
Increased survival of a cohort of patients with acquired immunodeficiency syndrome and cytomegalovirus retinitis who received sodium phosphonoformate (foscarnet).
    The American journal of medicine, 1993, Volume: 94, Issue:2

    Topics: Acquired Immunodeficiency Syndrome; Cohort Studies; Cytomegalovirus Infections; Didanosine; Drug Tolerance; Follow-Up Studies; Foscarnet; Ganciclovir; Humans; Infusions, Intravenous; Injections, Intravenous; Retinitis; Survival Rate; Time Factors; Zidovudine

1993
Therapy for human immunodeficiency virus infection.
    The New England journal of medicine, 1993, Jun-10, Volume: 328, Issue:23

    Topics: Didanosine; Drug Resistance; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Protease Inhibitors; Zalcitabine; Zidovudine

1993
Current use of anti-HIV drugs in AIDS.
    The Journal of antimicrobial chemotherapy, 1993, Volume: 32 Suppl A

    Topics: Acquired Immunodeficiency Syndrome; Didanosine; Drug Therapy, Combination; Humans; Zalcitabine; Zidovudine

1993
Current management of HIV infection in children.
    Pediatric annals, 1993, Volume: 22, Issue:7

    Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Child; Child, Preschool; Didanosine; Drug Monitoring; HIV Infections; Humans; Infant; Infant, Newborn; Zidovudine

1993
Arguments against the chemoprophylactic use of zidovudine following occupational exposure to the human immunodeficiency virus.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1993, Volume: 16, Issue:3

    Topics: Didanosine; Health Personnel; HIV Infections; Humans; Occupational Exposure; Zidovudine

1993
Antiretroviral therapy of human immunodeficiency virus type-1 (HIV-1) infection.
    Australian and New Zealand journal of medicine, 1995, Volume: 25, Issue:4

    Topics: Antiviral Agents; Didanosine; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Reverse Transcriptase Inhibitors; Stavudine; Zalcitabine; Zidovudine

1995
Studies of zidovudine in combination with didanosine and zalcitabine.
    Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association, 1995, Volume: 10 Suppl 1

    Topics: Antiviral Agents; CD4 Lymphocyte Count; Clinical Trials as Topic; Didanosine; Disease Progression; Drug Resistance, Microbial; Drug Therapy, Combination; HIV; HIV Infections; Humans; Reverse Transcriptase Inhibitors; Safety; Zalcitabine; Zidovudine

1995
Managing HIV. Part 4: Primary therapy. 4.1 Antiretroviral therapies for HIV.
    The Medical journal of Australia, 1996, Mar-04, Volume: 164, Issue:5

    Topics: Antiviral Agents; Clinical Trials as Topic; Didanosine; Drug Therapy, Combination; HIV Infections; Humans; Multicenter Studies as Topic; Zalcitabine; Zidovudine

1996
Ups and downs--and ups in the antiviral therapy of HIV infection.
    Genitourinary medicine, 1996, Volume: 72, Issue:1

    Topics: AIDS-Related Complex; AIDS-Related Opportunistic Infections; Antiviral Agents; Didanosine; HIV Infections; Humans; Quality of Life; Randomized Controlled Trials as Topic; Zidovudine

1996
The role of antiretroviral therapy in the management of HIV infection in women.
    Clinical obstetrics and gynecology, 1996, Volume: 39, Issue:2

    Topics: Antiviral Agents; Clinical Trials as Topic; Didanosine; Female; HIV Infections; Humans; Infectious Disease Transmission, Vertical; Pregnancy; Pregnancy Complications, Infectious; Protease Inhibitors; Treatment Outcome; Zidovudine

1996
Clinical toxicity of antiretroviral nucleoside analogs.
    Antiviral research, 1996, Volume: 31, Issue:3

    Topics: Animals; Antiviral Agents; Didanosine; Humans; Lamivudine; Mitochondria; Nucleosides; Stavudine; Zalcitabine; Zidovudine

1996
Guide to major clinical trials of antiretroviral therapy administered to patients infected with human immunodeficiency virus.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1996, Volume: 23, Issue:1

    Topics: Anti-HIV Agents; Clinical Trials as Topic; Didanosine; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; Humans; Lamivudine; Meta-Analysis as Topic; Reverse Transcriptase Inhibitors; Stavudine; Zalcitabine; Zidovudine

1996
Pediatric human immunodeficiency virus infection.
    Clinical microbiology reviews, 1996, Volume: 9, Issue:4

    Topics: AIDS-Related Opportunistic Infections; Anti-HIV Agents; Central Nervous System Diseases; Child; Child, Preschool; Cytomegalovirus Infections; Didanosine; Disease Transmission, Infectious; Eye Diseases; Female; Gastrointestinal Diseases; Heart Diseases; Hematologic Diseases; Herpes Simplex; Herpes Zoster; HIV Infections; Humans; Incidence; Infant; Infant, Newborn; Infectious Disease Transmission, Vertical; Kidney Diseases; Male; Neoplasms; Pregnancy; Prevalence; Risk Factors; Sexual Behavior; Skin Diseases; Transfusion Reaction; Zidovudine

1996
Pediatric HIV infection: a primer for pharmacists.
    Journal of the American Pharmaceutical Association (Washington, D.C. : 1996), 1996, Volume: NS36, Issue:10

    Topics: Adolescent; Anti-HIV Agents; Child; Child, Preschool; Didanosine; Female; HIV Infections; Humans; Infant; Infant, Newborn; Male; Pharmacists; Reverse Transcriptase Inhibitors; Zalcitabine; Zidovudine

1996
[Initial anti-retroviral treatment (therapeutic approach to patients without previous treatment)].
    Enfermedades infecciosas y microbiologia clinica, 1996, Volume: 14 Suppl 1

    Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Didanosine; HIV Infections; Humans; Zalcitabine; Zidovudine

1996
[Anti-retroviral treatment. Approach to previously treated patients].
    Enfermedades infecciosas y microbiologia clinica, 1996, Volume: 14 Suppl 1

    Topics: Anti-HIV Agents; Didanosine; Drug Therapy, Combination; HIV Infections; Humans; Zalcitabine; Zidovudine

1996
[Nucleoside analogs inhibiting reverse transcriptase: use in adult patient with HIV infection].
    Enfermedades infecciosas y microbiologia clinica, 1996, Volume: 14 Suppl 1

    Topics: Adult; Anti-HIV Agents; Clinical Trials as Topic; Didanosine; Dideoxynucleosides; Drug Resistance, Microbial; Drug Therapy, Combination; HIV Infections; Humans; Lamivudine; Reverse Transcriptase Inhibitors; Stavudine; Zalcitabine; Zidovudine

1996
[Anti-retroviral treatment. Treatment modification: toxicity management].
    Enfermedades infecciosas y microbiologia clinica, 1996, Volume: 14 Suppl 1

    Topics: Anti-HIV Agents; Didanosine; Drug Eruptions; Drug Therapy, Combination; Gastrointestinal Diseases; Hematologic Diseases; HIV Infections; Humans; Muscular Diseases; Reverse Transcriptase Inhibitors; Zalcitabine; Zidovudine

1996
[Antiretroviral treatment. Present and future of the combinations].
    Revista de neurologia, 1996, Volume: 24, Issue:136

    Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Didanosine; HIV-1; Humans; Zalcitabine; Zidovudine

1996
Antiretroviral therapy for pregnant women.
    American journal of obstetrics and gynecology, 1997, Volume: 176, Issue:2

    Topics: Anti-HIV Agents; Didanosine; Female; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Pregnancy; Pregnancy Complications, Infectious; Ritonavir; Saquinavir; Zalcitabine; Zidovudine

1997
Antiretroviral therapy: a guide to the most important trials.
    Schweizerische medizinische Wochenschrift, 1997, Mar-15, Volume: 127, Issue:11

    Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Clinical Trials as Topic; Didanosine; Drug Therapy, Combination; HIV Infections; Humans; Indinavir; Lamivudine; Nevirapine; Pyridines; Ritonavir; Saquinavir; Stavudine; Viral Load; Zalcitabine; Zidovudine

1997
[Infectious diseases that require world-wide control--HIV infections].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1997, Nov-10, Volume: 86, Issue:11

    Topics: Anti-HIV Agents; Communicable Disease Control; Didanosine; Drug Therapy, Combination; HIV Infections; Humans; International Cooperation; Protease Inhibitors; Reverse Transcriptase Inhibitors; Zidovudine

1997
[Antiretroviral treatment in human immunodeficiency virus infection].
    Annales de dermatologie et de venereologie, 1997, Volume: 124, Issue:9

    Topics: Antiviral Agents; Didanosine; Drug Interactions; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Ritonavir; Saquinavir; Stavudine; Treatment Outcome; Viral Load; Zalcitabine; Zidovudine

1997
Antiretroviral chemotherapy.
    Current clinical topics in infectious diseases, 1998, Volume: 18

    Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Delavirdine; Didanosine; Dideoxynucleosides; HIV Infections; HIV-1; Humans; Indinavir; Lamivudine; Nelfinavir; Nevirapine; Oxazines; Ritonavir; Saquinavir; Stavudine; Zalcitabine; Zidovudine

1998
Toxicity of antiretroviral agents.
    The American journal of medicine, 1997, May-19, Volume: 102, Issue:5B

    Topics: Anti-HIV Agents; Didanosine; Health Personnel; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Occupational Exposure; Reverse Transcriptase Inhibitors; Ritonavir; Saquinavir; Stavudine; Zalcitabine; Zidovudine

1997
Peripheral neuropathy with nucleoside antiretrovirals: risk factors, incidence and management.
    Drug safety, 1998, Volume: 19, Issue:6

    Topics: Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Didanosine; Drug Therapy, Combination; HIV Infections; Humans; Peripheral Nervous System Diseases; Reverse Transcriptase Inhibitors; Stavudine; Zalcitabine; Zidovudine

1998
[Vasculitis associated with antiviral vaccines and antiviral agents].
    Pathologie-biologie, 1999, Volume: 47, Issue:3

    Topics: Acyclovir; Antiviral Agents; Didanosine; Hepatitis B Vaccines; Humans; Interferons; Vasculitis; Viral Vaccines; Zidovudine

1999
[Response of fetal macrophages in the placenta of pregnant HIV-positive patients with and without antiretroviral treatment].
    Ginecologia y obstetricia de Mexico, 1999, Volume: 67

    Topics: Antiviral Agents; Didanosine; Female; HIV Infections; HIV Seropositivity; Humans; Macrophages; Pregnancy; Pregnancy Complications, Infectious; Retroviridae; Zidovudine

1999
Zidovudine, didanosine, and zalcitabine in the treatment of HIV infection: meta-analyses of the randomised evidence. HIV Trialists' Collaborative Group.
    Lancet (London, England), 1999, Jun-12, Volume: 353, Issue:9169

    Topics: Acquired Immunodeficiency Syndrome; Adult; Anti-HIV Agents; Didanosine; Disease Progression; Drug Therapy, Combination; Female; HIV Infections; Humans; Male; Randomized Controlled Trials as Topic; Survival Rate; Time Factors; Zalcitabine; Zidovudine

1999
Relation of peripheral neuropathy to HIV treatment in four randomized clinical trials including didanosine.
    Clinical therapeutics, 1999, Volume: 21, Issue:7

    Topics: Adolescent; Adult; Aged; Anti-HIV Agents; CD4 Lymphocyte Count; Child, Preschool; Data Collection; Didanosine; Dose-Response Relationship, Drug; Double-Blind Method; Drug Interactions; Female; Humans; Male; Middle Aged; Peripheral Nervous System Diseases; Polypharmacy; Randomized Controlled Trials as Topic; Risk Factors; Time Factors; Zalcitabine; Zidovudine

1999
Antiretrovirals.
    Mayo Clinic proceedings, 1999, Volume: 74, Issue:12

    Topics: Adolescent; Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Carbamates; Cyclopropanes; Delavirdine; Didanosine; Dideoxynucleosides; Female; Furans; HIV Infections; Humans; Indinavir; Lamivudine; Nelfinavir; Nevirapine; Oxazines; Pregnancy; Pregnancy Complications, Infectious; Protease Inhibitors; Reverse Transcriptase Inhibitors; Ritonavir; Saquinavir; Stavudine; Sulfonamides; Zalcitabine; Zidovudine

1999
Stavudine plus a non-thymidine nucleoside reverse transcriptase inhibitor as a backbone for highly active antiretroviral therapy.
    Antiviral therapy, 1998, Volume: 3 Suppl 4

    Topics: Clinical Trials as Topic; Didanosine; Drug Therapy, Combination; HIV Infections; Humans; Lamivudine; Retroviridae; Reverse Transcriptase Inhibitors; Stavudine; Zidovudine

1998
Meta-analysis of two randomized controlled trials comparing combined zidovudine and didanosine therapy with combined zidovudine, didanosine, and nevirapine therapy in patients with HIV. INCAS study team.
    Journal of acquired immune deficiency syndromes (1999), 1999, Nov-01, Volume: 22, Issue:3

    Topics: Adult; Didanosine; Drug Therapy, Combination; Female; HIV Infections; Humans; Male; Middle Aged; Multivariate Analysis; Nevirapine; Proportional Hazards Models; Viral Load; Zidovudine

1999
Zidovudine (AZT) versus AZT plus didanosine (ddI) versus AZT plus zalcitabine (ddC) in HIV infected adults.
    The Cochrane database of systematic reviews, 2000, Issue:2

    Topics: Adult; Anti-HIV Agents; Didanosine; Drug Administration Schedule; Drug Therapy, Combination; HIV Infections; Humans; Zalcitabine; Zidovudine

2000
Zidovudine (AZT) versus AZT plus didanosine (ddI) versus AZT plus zalcitabine (ddC) in HIV infected adults.
    The Cochrane database of systematic reviews, 2000, Issue:3

    Topics: Adult; Anti-HIV Agents; Didanosine; Drug Administration Schedule; Drug Therapy, Combination; HIV Infections; Humans; Randomized Controlled Trials as Topic; Zalcitabine; Zidovudine

2000
Antiretroviral agents.
    IARC monographs on the evaluation of carcinogenic risks to humans, 2000, Volume: 76

    Topics: Acyclovir; Animals; Antiviral Agents; Carcinogens; Didanosine; Disease Models, Animal; Evidence-Based Medicine; Humans; Intestinal Absorption; Neoplasms; Risk Factors; Tissue Distribution; Zalcitabine; Zidovudine

2000
Systematic review of combination antiretroviral therapy with didanosine plus hydroxyurea: a partial solution to Africa's HIV/AIDS problem?
    International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2001, Volume: 5, Issue:1

    Topics: Africa; Anti-HIV Agents; CD4 Lymphocyte Count; Didanosine; Drug Therapy, Combination; HIV Infections; Humans; Hydroxyurea; MEDLINE; Treatment Outcome; Viral Load; Zidovudine

2001
The role of didanosine in the management of HIV-1 infection.
    Antiviral therapy, 1997, Volume: 2, Issue:3

    Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Didanosine; Drug Therapy, Combination; HIV-1; Humans; Zidovudine

1997
Meta-analysis of five randomized controlled trials comparing continuation of zidovudine versus switching to didanosine in HIV-infected individuals.
    Antiviral therapy, 1997, Volume: 2, Issue:4

    Topics: AIDS Dementia Complex; Anti-HIV Agents; CD4 Lymphocyte Count; Didanosine; HIV Infections; Humans; Incidence; Randomized Controlled Trials as Topic; Zidovudine

1997
Pediatric antiretroviral therapy: from research to practice.
    Pediatric AIDS and HIV infection, 1996, Volume: 7, Issue:1

    Topics: Adolescent; Age Factors; Anti-HIV Agents; Child; Child, Preschool; Didanosine; HIV Infections; HIV-1; Humans; Infant; Infant, Newborn; Viral Load; Virus Replication; Zidovudine

1996
[Treatment of chronic hepatitis C in patients coinfected with HIV: tolerability, drug interactions, therapeutic indications].
    Gastroenterologie clinique et biologique, 2002, Volume: 26 Spec No 2

    Topics: Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Clinical Trials as Topic; Didanosine; Drug Interactions; Hepatitis C, Chronic; HIV Infections; Humans; Interferon-alpha; Life Style; Mitochondria; Monitoring, Physiologic; Multicenter Studies as Topic; Patient Selection; Randomized Controlled Trials as Topic; Retrospective Studies; Reverse Transcriptase Inhibitors; Ribavirin; Stavudine; Time Factors; Viral Load; Zidovudine

2002
[Antiretrovirals].
    Nihon rinsho. Japanese journal of clinical medicine, 2003, Volume: 61 Suppl 2

    Topics: Acidosis, Lactic; Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Didanosine; Hemophilia A; Hemorrhage; HIV Protease Inhibitors; HIV-Associated Lipodystrophy Syndrome; Humans; Indinavir; Nevirapine; Oxazines; Reverse Transcriptase Inhibitors; Stavudine; Zidovudine

2003
The continuing evolution of HIV therapy.
    The AIDS reader, 2003, Volume: 13, Issue:12

    Topics: Adenine; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Atazanavir Sulfate; Benzoxazines; Carbamates; CD4 Lymphocyte Count; Cyclopropanes; Delayed-Action Preparations; Deoxycytidine; Didanosine; Dideoxynucleosides; Drug Monitoring; Emtricitabine; Furans; HIV Infections; Humans; Lamivudine; Nevirapine; Oligopeptides; Organophosphates; Organophosphonates; Organophosphorus Compounds; Oxazines; Pyridines; Randomized Controlled Trials as Topic; Stavudine; Sulfonamides; Tenofovir; Treatment Outcome; Viral Load; Zidovudine

2003
Prognostic factors in lactic acidosis syndrome caused by nucleoside reverse transcriptase inhibitors: report of eight cases and review of the literature.
    AIDS patient care and STDs, 2004, Volume: 18, Issue:7

    Topics: Acidosis, Lactic; Adult; Didanosine; Female; HIV Infections; Humans; Lamivudine; Male; Middle Aged; New York; Reverse Transcriptase Inhibitors; Stavudine; Syndrome; Zidovudine

2004
Nucleoside reverse transcriptase inhibitors, mitochondrial DNA and AIDS therapy.
    Antiviral therapy, 2005, Volume: 10 Suppl 2

    Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Didanosine; DNA Replication; DNA, Mitochondrial; Humans; Lamivudine; Mitochondria; Nucleosides; Reverse Transcriptase Inhibitors; Stavudine; Zidovudine

2005
[Antiretrovirals].
    Nihon rinsho. Japanese journal of clinical medicine, 2007, Feb-28, Volume: 65 Suppl 2 Pt. 1

    Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Didanosine; Drug Prescriptions; Drug Therapy, Combination; Humans; Lopinavir; Protease Inhibitors; Pyrimidinones; Reverse Transcriptase Inhibitors; Stavudine; Zidovudine

2007

Trials

212 trial(s) available for zidovudine and didanosine

ArticleYear
A controlled trial comparing continued zidovudine with didanosine in human immunodeficiency virus infection. The NIAID AIDS Clinical Trials Group.
    The New England journal of medicine, 1992, Aug-27, Volume: 327, Issue:9

    Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Complex; CD4-Positive T-Lymphocytes; Didanosine; Double-Blind Method; Female; HIV Core Protein p24; HIV Infections; Humans; Leukocyte Count; Male; Patient Compliance; Survival Rate; Zidovudine

1992
Didanosine for zidovudine-intolerant patients with HIV disease.
    Lancet (London, England), 1992, Nov-28, Volume: 340, Issue:8831

    Topics: Didanosine; Europe; HIV Infections; HIV-1; Humans; Survival Rate; Zidovudine

1992
Continued zidovudine or didanosine for human immunodeficiency virus infection.
    The New England journal of medicine, 1992, Nov-26, Volume: 327, Issue:22

    Topics: Acquired Immunodeficiency Syndrome; Didanosine; Humans; Patient Dropouts; Zidovudine

1992
Continued zidovudine or didanosine for human immunodeficiency virus infection.
    The New England journal of medicine, 1992, Nov-26, Volume: 327, Issue:22

    Topics: Acquired Immunodeficiency Syndrome; Didanosine; Humans; Zidovudine

1992
Effects of therapy with didanosine on hematologic parameters in patients with advanced human immunodeficiency virus disease.
    Blood, 1992, Dec-15, Volume: 80, Issue:12

    Topics: Acquired Immunodeficiency Syndrome; Adult; AIDS-Related Complex; CD4 Antigens; Didanosine; Female; Granulocytes; Hemoglobins; HIV Seropositivity; Humans; Leukocyte Count; Male; Platelet Count; T-Lymphocyte Subsets; Time Factors; Zidovudine

1992
Nucleoside therapy for HIV infection--some answers, many questions.
    The New England journal of medicine, 1992, Aug-27, Volume: 327, Issue:9

    Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Complex; Didanosine; HIV Infections; Humans; Zidovudine

1992
Phase I study of 2'-3'-dideoxyinosine administered orally twice daily to patients with AIDS or AIDS-related complex and hematologic intolerance to zidovudine.
    The American journal of medicine, 1991, Volume: 91, Issue:5

    Topics: Acquired Immunodeficiency Syndrome; Administration, Oral; Adult; AIDS-Related Complex; Didanosine; Drug Evaluation; Female; Hemoglobins; Humans; Hypocalcemia; Male; Pancreatitis; Peripheral Nervous System Diseases; Zidovudine

1991
Chemotherapy of human immunodeficiency virus infections: current practice and future prospects.
    The Journal of infectious diseases, 1990, Volume: 161, Issue:5

    Topics: Animals; Antiviral Agents; Didanosine; DNA Nucleotidyltransferases; DNA Replication; Drug Therapy, Combination; Endopeptidases; HIV Infections; HIV-1; Humans; Integrases; RNA-Directed DNA Polymerase; Virus Replication; Zalcitabine; Zidovudine

1990
Retinal toxicity in human immunodeficiency virus-infected children treated with 2',3'-dideoxyinosine.
    American journal of ophthalmology, 1992, Jan-15, Volume: 113, Issue:1

    Topics: Atrophy; Child; Child, Preschool; Didanosine; Drug Evaluation; Electrooculography; Electroretinography; Female; Follow-Up Studies; Fundus Oculi; HIV Infections; HIV-1; Humans; Male; Pigment Epithelium of Eye; Prospective Studies; Retina; Retinal Diseases; Zidovudine

1992
HIV-seropositive thrombocytopenia: the action of zidovudine.
    AIDS (London, England), 1991, Volume: 5, Issue:11

    Topics: Adult; Didanosine; Female; HIV Seropositivity; Humans; Male; Middle Aged; Platelet Count; Platelet Glycoprotein GPIb-IX Complex; Platelet Membrane Glycoproteins; Thrombocytopenia; Zidovudine

1991
Treatment of AIDS with combinations of antiretroviral agents.
    The American journal of medicine, 1991, Apr-10, Volume: 90, Issue:4A

    Topics: Acquired Immunodeficiency Syndrome; Clinical Trials as Topic; Didanosine; Drug Therapy, Combination; Humans; Interferon Type I; Recombinant Proteins; Zalcitabine; Zidovudine

1991
New drugs being tested for better AIDS treatment.
    Ohio medicine : journal of the Ohio State Medical Association, 1991, Volume: 87, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Didanosine; Humans; Zidovudine

1991
Effects of antiretroviral dideoxynucleosides on polymorphonuclear leukocyte function.
    Antimicrobial agents and chemotherapy, 1990, Volume: 34, Issue:9

    Topics: Cell Survival; Chemotaxis, Leukocyte; Didanosine; HIV Infections; HIV-1; Humans; Neutrophils; Phagocytosis; Superoxides; Zalcitabine; Zidovudine

1990
Expanding AIDS drug availability.
    JAMA, 1989, Sep-08, Volume: 262, Issue:10

    Topics: Acquired Immunodeficiency Syndrome; Clinical Trials as Topic; Didanosine; Dideoxynucleosides; Humans; Zidovudine

1989
AIDS treatment: 'parallel trick' for ddI.
    Nature, 1989, Oct-12, Volume: 341, Issue:6242

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Clinical Trials as Topic; Didanosine; Drug Evaluation; Humans; Zidovudine

1989
FDA expands testing of anti-AIDS drugs.
    New York state journal of medicine, 1989, Volume: 89, Issue:9

    Topics: Acquired Immunodeficiency Syndrome; Adult; AIDS Dementia Complex; AIDS-Related Complex; Antiviral Agents; Clinical Trials as Topic; Didanosine; Humans; Infant; Infant, Newborn; United States; United States Food and Drug Administration; Zalcitabine; Zidovudine

1989
Long-term persistence of zidovudine resistance mutations in plasma isolates of human immunodeficiency virus type 1 of dideoxyinosine-treated patients removed from zidovudine therapy.
    The Journal of infectious diseases, 1994, Volume: 169, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Cloning, Molecular; Didanosine; DNA, Viral; Dose-Response Relationship, Drug; Drug Resistance, Microbial; HIV Reverse Transcriptase; HIV-1; Humans; Microbial Sensitivity Tests; Mutation; Polymerase Chain Reaction; RNA-Directed DNA Polymerase; Zidovudine

1994
Drug resistance and heterogeneous long-term virologic responses of human immunodeficiency virus type 1-infected subjects to zidovudine and didanosine combination therapy. The AIDS Clinical Trials Group 143 Virology Team.
    The Journal of infectious diseases, 1995, Volume: 172, Issue:1

    Topics: Amino Acid Sequence; Base Sequence; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; Codon; Didanosine; DNA Primers; Drug Resistance, Microbial; Drug Resistance, Multiple; Drug Therapy, Combination; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Molecular Sequence Data; Point Mutation; Polymerase Chain Reaction; RNA-Directed DNA Polymerase; RNA, Viral; Zidovudine

1995
A randomized trial of the activity and safety of Ro 24-7429 (Tat antagonist) versus nucleoside for human immunodeficiency virus infection. The AIDS Clinical Trials Group 213 Team.
    The Journal of infectious diseases, 1995, Volume: 172, Issue:5

    Topics: Adult; Antiviral Agents; Benzodiazepines; CD4 Lymphocyte Count; Didanosine; Dose-Response Relationship, Drug; Female; Gene Products, tat; HIV Core Protein p24; HIV Infections; Humans; Male; Middle Aged; Pyrroles; tat Gene Products, Human Immunodeficiency Virus; Time Factors; Zidovudine

1995
Decreased human immunodeficiency virus type 1 plasma viremia during antiretroviral therapy reflects downregulation of viral replication in lymphoid tissue.
    Proceedings of the National Academy of Sciences of the United States of America, 1995, Jun-20, Volume: 92, Issue:13

    Topics: Adult; Didanosine; DNA, Viral; Female; HIV Infections; HIV-1; Humans; Lymph Nodes; Lymphocytes; Male; Time Factors; Viremia; Zidovudine

1995
A dose comparison study of didanosine in patients with very advanced HIV infection who are intolerant to or clinically deteriorate on zidovudine. German ddI Trial Group.
    AIDS (London, England), 1995, Volume: 9, Issue:5

    Topics: Acquired Immunodeficiency Syndrome; Adult; Aged; AIDS-Related Complex; CD4 Lymphocyte Count; Didanosine; Disease Progression; Drug Evaluation; Drug Tolerance; Female; Humans; Male; Middle Aged; Pancreatitis; Survival Rate; Treatment Outcome; Zidovudine

1995
Pharmacokinetics of simultaneously administered zidovudine and didanosine in HIV-seropositive male patients.
    Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association, 1995, Sep-01, Volume: 10, Issue:1

    Topics: Adult; Cross-Over Studies; Didanosine; Drug Interactions; Drug Therapy, Combination; HIV Seropositivity; Humans; Male; Metabolic Clearance Rate; Zidovudine

1995
Pharmacokinetics of zidovudine and dideoxyinosine alone and in combination in children with HIV infection.
    British journal of clinical pharmacology, 1995, Volume: 39, Issue:5

    Topics: Administration, Oral; Adolescent; Child; Child, Preschool; Didanosine; Drug Interactions; Drug Therapy, Combination; Half-Life; HIV Infections; Humans; Male; Radioimmunoassay; Zidovudine

1995
Didanosine compared with continued zidovudine therapy for HIV-infected patients with 200 to 500 CD4 cells/mm3. A double-blind, randomized, controlled trial. Canadian HIV Trials Network Protocol 002 Study Group.
    Annals of internal medicine, 1995, Oct-15, Volume: 123, Issue:8

    Topics: Adult; CD4 Lymphocyte Count; Didanosine; Disease Progression; Double-Blind Method; Drug Resistance, Microbial; Female; HIV Infections; Humans; Male; Prospective Studies; Zidovudine

1995
Zidovudine compared with didanosine in patients with advanced HIV type 1 infection and little or no previous experience with zidovudine. AIDS Clinical Trials Group.
    Archives of internal medicine, 1995, May-08, Volume: 155, Issue:9

    Topics: Acquired Immunodeficiency Syndrome; Adult; AIDS-Related Opportunistic Infections; CD4 Lymphocyte Count; Didanosine; Double-Blind Method; Drug Administration Schedule; Female; Humans; Male; Patient Compliance; Severity of Illness Index; Survival Analysis; Treatment Outcome; Zidovudine

1995
Randomized study of didanosine monotherapy and combination therapy with zidovudine in hemophilic and nonhemophilic subjects with asymptomatic human immunodeficiency virus-1 infection. AIDS Clinical Trial Groups.
    Blood, 1995, May-01, Volume: 85, Issue:9

    Topics: Adult; CD4 Lymphocyte Count; Chemical and Drug Induced Liver Injury; Didanosine; Drug Therapy, Combination; Female; Hemophilia A; HIV Core Protein p24; HIV Infections; HIV-1; Humans; Male; Safety; Treatment Outcome; Viremia; Zidovudine

1995
Human immunodeficiency virus type 1 (HIV-1) viremia changes and development of drug-related mutations in patients with symptomatic HIV-1 infection receiving alternating or simultaneous zidovudine and didanosine therapy.
    The Journal of infectious diseases, 1995, Volume: 171, Issue:5

    Topics: Adult; Base Sequence; CD4 Lymphocyte Count; Codon; Didanosine; Drug Resistance, Microbial; Drug Therapy, Combination; Female; Genes, pol; HIV Core Protein p24; HIV Infections; HIV-1; Humans; Male; Middle Aged; Molecular Sequence Data; Mutation; RNA, Viral; Viremia; Zidovudine

1995
Five-year follow-up of a phase I study of didanosine in patients with advanced human immunodeficiency virus infection.
    The Journal of infectious diseases, 1995, Volume: 171, Issue:5

    Topics: Adult; CD4 Lymphocyte Count; Didanosine; Disease Progression; Drug Therapy, Combination; Female; Follow-Up Studies; HIV Infections; Humans; Male; Middle Aged; Survival Rate; Zidovudine

1995
Treatment options in zidovudine intolerance or failure.
    AIDS (London, England), 1994, Volume: 8 Suppl 3

    Topics: Acquired Immunodeficiency Syndrome; Adult; Didanosine; Female; Follow-Up Studies; Humans; Male; Survival Rate; Time Factors; Treatment Failure; Zalcitabine; Zidovudine

1994
Human immunodeficiency virus type 1 quantitative cell microculture as a measure of antiviral efficacy in a multicenter clinical trial.
    The Journal of infectious diseases, 1995, Volume: 171, Issue:2

    Topics: CD4 Lymphocyte Count; Didanosine; Drug Therapy, Combination; HIV Core Protein p24; HIV Infections; HIV-1; Humans; Leukocytes, Mononuclear; Treatment Outcome; Virus Cultivation; Zidovudine

1995
Zidovudine resistance and HIV-1 disease progression during antiretroviral therapy. AIDS Clinical Trials Group Protocol 116B/117 Team and the Virology Committee Resistance Working Group.
    Annals of internal medicine, 1995, Mar-15, Volume: 122, Issue:6

    Topics: Acquired Immunodeficiency Syndrome; Adult; CD4 Lymphocyte Count; Didanosine; Drug Resistance, Microbial; Drug Therapy, Combination; Female; HIV-1; Humans; Male; Prognosis; Proportional Hazards Models; Retrospective Studies; Risk Factors; Zidovudine

1995
Something better than zidovudine for children.
    Lancet (London, England), 1995, Feb-25, Volume: 345, Issue:8948

    Topics: Adolescent; Child; Child, Preschool; Didanosine; Double-Blind Method; Drug Therapy, Combination; HIV Infections; Humans; Infant; Zidovudine

1995
A randomized pilot study of alternating or simultaneous zidovudine and didanosine therapy in patients with symptomatic human immunodeficiency virus infection.
    The Journal of infectious diseases, 1994, Volume: 169, Issue:1

    Topics: Administration, Oral; Adolescent; Adult; AIDS-Related Opportunistic Infections; beta 2-Microglobulin; Body Weight; CD4-Positive T-Lymphocytes; Didanosine; Drug Administration Schedule; Drug Therapy, Combination; Female; Follow-Up Studies; HIV Core Protein p24; HIV Infections; Humans; Leukocyte Count; Male; Middle Aged; Pancreatitis; Pilot Projects; Zidovudine

1994
Didanosine compared with continuation of zidovudine in HIV-infected patients with signs of clinical deterioration while receiving zidovudine. A randomized, double-blind clinical trial. The Bristol-Myers Squibb AI454-010 Study Group.
    Annals of internal medicine, 1994, Mar-01, Volume: 120, Issue:5

    Topics: Acquired Immunodeficiency Syndrome; Adult; Aged; AIDS-Related Complex; CD4-Positive T-Lymphocytes; Didanosine; Double-Blind Method; Female; Humans; Leukocyte Count; Male; Middle Aged; Zidovudine

1994
A comparative trial of didanosine or zalcitabine after treatment with zidovudine in patients with human immunodeficiency virus infection. The Terry Beirn Community Programs for Clinical Research on AIDS.
    The New England journal of medicine, 1994, Mar-10, Volume: 330, Issue:10

    Topics: Acquired Immunodeficiency Syndrome; Adult; CD4-Positive T-Lymphocytes; Didanosine; Female; Follow-Up Studies; HIV Infections; Humans; Leukocyte Count; Male; Risk; Zalcitabine; Zidovudine

1994
Zidovudine and didanosine combination therapy in children with human immunodeficiency virus infection.
    Pediatrics, 1994, Volume: 93, Issue:2

    Topics: Adolescent; Adult; CD4-Positive T-Lymphocytes; Child; Child, Preschool; Didanosine; Drug Administration Schedule; Drug Therapy, Combination; Female; HIV Infections; Humans; Infant; Leukocyte Count; Male; Treatment Outcome; Zidovudine

1994
A phase II study of effect of addition of trichosanthin to zidovudine in patients with HIV disease and failing antiretroviral agents.
    AIDS research and human retroviruses, 1994, Volume: 10, Issue:4

    Topics: Adolescent; Adult; Aged; CD4-Positive T-Lymphocytes; Didanosine; Drug Therapy, Combination; Female; HIV Infections; Humans; Leukocyte Count; Liver; Male; Middle Aged; Trichosanthin; Zidovudine

1994
AIDS dementia complex and didanosine.
    Lancet (London, England), 1994, Sep-10, Volume: 344, Issue:8924

    Topics: Acquired Immunodeficiency Syndrome; AIDS Dementia Complex; Didanosine; Double-Blind Method; Follow-Up Studies; HIV-1; Humans; Zidovudine

1994
Antiretroviral therapy is associated with a decrease in unintegrated HIV-1 DNA in pediatric patients.
    Journal of acquired immune deficiency syndromes, 1994, Volume: 7, Issue:12

    Topics: CD4 Lymphocyte Count; Child, Preschool; Didanosine; DNA, Viral; Drug Therapy, Combination; Female; HIV Core Protein p24; HIV Infections; HIV-1; Humans; Infant; Leukocytes, Mononuclear; Male; Polymerase Chain Reaction; Viremia; Zidovudine

1994
Pharmacokinetic evaluation of the combination of zidovudine and didanosine in children with human immunodeficiency virus infection.
    The Journal of pediatrics, 1994, Volume: 125, Issue:1

    Topics: Adolescent; Adult; Child; Child, Preschool; Didanosine; Dose-Response Relationship, Drug; Drug Interactions; Drug Monitoring; Drug Therapy, Combination; Female; HIV Infections; Humans; Infant; Male; Zidovudine

1994
Pharmacokinetics of zidovudine and dideoxyinosine alone and in combination in patients with the acquired immunodeficiency syndrome.
    British journal of clinical pharmacology, 1994, Volume: 37, Issue:5

    Topics: Acquired Immunodeficiency Syndrome; Administration, Oral; Adult; Chromatography, High Pressure Liquid; Didanosine; Drug Interactions; Drug Therapy, Combination; Half-Life; Humans; Male; Metabolic Clearance Rate; Middle Aged; Zidovudine

1994
Combination therapy with zidovudine and didanosine selects for drug-resistant human immunodeficiency virus type 1 strains with unique patterns of pol gene mutations.
    The Journal of infectious diseases, 1994, Volume: 169, Issue:4

    Topics: Amino Acids; Base Sequence; Cells, Cultured; Codon; Didanosine; DNA Primers; DNA, Viral; Drug Resistance, Microbial; Drug Therapy, Combination; Genes, pol; HIV Seropositivity; HIV-1; Humans; Molecular Sequence Data; Mutation; Polymerase Chain Reaction; Proviruses; RNA, Viral; Zidovudine

1994
Uric acid and didanosine compliance in AIDS clinical trials: an analysis of AIDS Clinical Trials Group protocols 116A and 116B/117.
    Journal of acquired immune deficiency syndromes, 1993, Volume: 6, Issue:11

    Topics: Adult; Clinical Protocols; Cohort Studies; Didanosine; Double-Blind Method; Female; HIV Infections; Humans; Male; Patient Compliance; Sensitivity and Specificity; Uric Acid; Zidovudine

1993
Combination therapy with zidovudine and didanosine compared with zidovudine alone in HIV-1 infection.
    Annals of internal medicine, 1993, Oct-15, Volume: 119, Issue:8

    Topics: Adult; CD4 Antigens; Cell Count; Didanosine; Drug Administration Schedule; Drug Interactions; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Male; RNA, Viral; Zidovudine

1993
Increased survival of a cohort of patients with acquired immunodeficiency syndrome and cytomegalovirus retinitis who received sodium phosphonoformate (foscarnet).
    The American journal of medicine, 1993, Volume: 94, Issue:2

    Topics: Acquired Immunodeficiency Syndrome; Cohort Studies; Cytomegalovirus Infections; Didanosine; Drug Tolerance; Follow-Up Studies; Foscarnet; Ganciclovir; Humans; Infusions, Intravenous; Injections, Intravenous; Retinitis; Survival Rate; Time Factors; Zidovudine

1993
Longitudinal analysis of responses to oral didanosine therapy following zidovudine therapy in advanced infection with human immunodeficiency virus.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1993, Volume: 16 Suppl 1

    Topics: Administration, Oral; Adult; Blood Cell Count; Didanosine; Female; Hemoglobins; HIV Infections; Humans; Longitudinal Studies; Male; Middle Aged; Retrospective Studies; Treatment Outcome; Zidovudine

1993
Long-term follow-up of didanosine administered orally twice daily to patients with advanced human immunodeficiency virus infection and hematologic intolerance of zidovudine.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1993, Volume: 16 Suppl 1

    Topics: Administration, Oral; Adult; Didanosine; Drug Administration Schedule; Female; Follow-Up Studies; Hematologic Diseases; HIV Infections; Humans; Male; Middle Aged; Zidovudine

1993
Detection of human immunodeficiency virus type 1 in semen: effects of disease stage and nucleoside therapy.
    The Journal of infectious diseases, 1993, Volume: 167, Issue:4

    Topics: Anti-Bacterial Agents; Cross-Sectional Studies; Didanosine; DNA, Viral; Drug Therapy, Combination; HIV Seropositivity; HIV-1; Humans; Leukocyte Count; Longitudinal Studies; Male; RNA, Viral; Semen; T-Lymphocytes; Zidovudine

1993
Pharmacokinetics of zidovudine and didanosine during combination therapy.
    Antiviral research, 1995, Volume: 27, Issue:4

    Topics: Adult; Didanosine; Drug Therapy, Combination; Female; HIV Infections; Humans; Male; Zidovudine

1995
Tolerance of a triple combination therapy with zidovudine, didanosine and interferon-alpha in seven HIV-infected patients.
    AIDS (London, England), 1995, Volume: 9, Issue:11

    Topics: Antiviral Agents; Didanosine; Drug Therapy, Combination; HIV Infections; Humans; Interferon-alpha; Zidovudine

1995
Study on didanosine concentrations in cerebrospinal fluid. Implications for the treatment and prevention of AIDS dementia complex.
    Pharmacy world & science : PWS, 1995, Nov-24, Volume: 17, Issue:6

    Topics: Acquired Immunodeficiency Syndrome; AIDS Dementia Complex; Antiviral Agents; Didanosine; Humans; Individuality; Zidovudine

1995
Combination therapy with ZDV + DDI versus ZDV + DDC in patients with progression of HIV-infection under treatment with ZDV.
    Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association, 1996, Apr-15, Volume: 11, Issue:5

    Topics: Adult; Antiviral Agents; CD4 Lymphocyte Count; Didanosine; Disease Progression; Drug Therapy, Combination; Female; Follow-Up Studies; HIV Infections; Humans; Male; Middle Aged; Reverse Transcriptase Inhibitors; Survival Analysis; Treatment Outcome; Zalcitabine; Zidovudine

1996
Patterns of opportunistic infections in patients with HIV infection.
    Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association, 1996, May-01, Volume: 12, Issue:1

    Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; CD4 Lymphocyte Count; Cohort Studies; Cytomegalovirus Infections; Didanosine; Double-Blind Method; Female; HIV Infections; HIV-1; Humans; Male; Mycobacterium avium-intracellulare Infection; Mycoses; Pneumonia, Pneumocystis; Prospective Studies; Retrospective Studies; Risk Factors; Survival Rate; Zidovudine

1996
Impact of missing data due to dropouts on estimates of the treatment effect in a randomized trial of antiretroviral therapy for HIV-infected individuals. Canadian HIV Trials Network A002 Study Group.
    Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association, 1996, May-01, Volume: 12, Issue:1

    Topics: Antiviral Agents; Bias; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; Data Interpretation, Statistical; Didanosine; Double-Blind Method; HIV Infections; Humans; Patient Dropouts; Randomized Controlled Trials as Topic; Reproducibility of Results; Treatment Outcome; Zidovudine

1996
Nevirapine, zidovudine, and didanosine compared with zidovudine and didanosine in patients with HIV-1 infection. A randomized, double-blind, placebo-controlled trial. National Institute of Allergy and Infectious Diseases AIDS Clinical Trials Group Protoco
    Annals of internal medicine, 1996, Jun-15, Volume: 124, Issue:12

    Topics: Adult; CD4 Lymphocyte Count; Didanosine; Disease Progression; Double-Blind Method; Drug Therapy, Combination; Erythema; Female; HIV Infections; HIV-1; Humans; Male; Nevirapine; Prospective Studies; Pyridines; Reverse Transcriptase Inhibitors; RNA, Viral; Zidovudine

1996
Survival in HIV-infected patients who have received zidovudine: comparison of combination therapy with sequential monotherapy and continued zidovudine monotherapy. Multicenter AIDS Cohort Study Group.
    Annals of internal medicine, 1996, Jun-15, Volume: 124, Issue:12

    Topics: Antiviral Agents; CD4 Lymphocyte Count; Didanosine; Disease Progression; Drug Administration Schedule; Drug Therapy, Combination; HIV Seropositivity; Humans; Longitudinal Studies; Male; Proportional Hazards Models; Zalcitabine; Zidovudine

1996
Virologic and immunologic benefits of initial combination therapy with zidovudine and zalcitabine or didanosine compared with zidovudine monotherapy. Wellcome Resistance Study Collaborative Group.
    The Journal of infectious diseases, 1996, Volume: 173, Issue:6

    Topics: Adult; Antiviral Agents; CD4 Lymphocyte Count; Didanosine; Disease Progression; Drug Resistance, Microbial; Drug Therapy, Combination; Female; HIV Infections; HIV Seropositivity; HIV-1; Humans; Male; Middle Aged; Phenotype; RNA, Viral; Zalcitabine; Zidovudine

1996
Switching from zidovudine to didanosine in patients with symptomatic HIV infection and disease progression. ddI Iberian Study Group.
    Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association, 1996, Volume: 12, Issue:3

    Topics: Acquired Immunodeficiency Syndrome; Adult; AIDS-Related Complex; AIDS-Related Opportunistic Infections; Antiviral Agents; Body Weight; CD4 Lymphocyte Count; Didanosine; Disease Progression; Female; HIV-1; Humans; Male; Pancreatitis; Zidovudine

1996
Double-blind placebo-controlled pilot trial of acemannan in advanced human immunodeficiency virus disease.
    Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association, 1996, Jun-01, Volume: 12, Issue:2

    Topics: Administration, Oral; Adult; Antiviral Agents; CD4 Lymphocyte Count; Didanosine; Double-Blind Method; Drug Therapy, Combination; Drug Tolerance; HIV Infections; Humans; Male; Mannans; Pilot Projects; Safety; Zidovudine

1996
[Comparative study of the placenta from HIV+ mothers. Ultrastructural analysis].
    Ginecologia y obstetricia de Mexico, 1996, Volume: 64

    Topics: Antiviral Agents; Didanosine; Female; HIV Infections; HIV Seropositivity; Humans; Infectious Disease Transmission, Vertical; Microscopy, Electron; Placenta; Pregnancy; Pregnancy Complications, Infectious; Zidovudine

1996
Human immunodeficiency virus type 1 drug susceptibility during zidovudine (AZT) monotherapy compared with AZT plus 2',3'-dideoxyinosine or AZT plus 2',3'-dideoxycytidine combination therapy. The protocol 34,225-02 Collaborative Group.
    Journal of virology, 1996, Volume: 70, Issue:9

    Topics: Antigens, CD; Antiviral Agents; CD4 Antigens; Coculture Techniques; Didanosine; Drug Resistance, Microbial; Drug Therapy, Combination; Genotype; HeLa Cells; HIV Reverse Transcriptase; HIV Seropositivity; HIV-1; Humans; Lymphocytes; Microbial Sensitivity Tests; Phenotype; Point Mutation; RNA-Directed DNA Polymerase; Zalcitabine; Zidovudine

1996
Delta: a randomised double-blind controlled trial comparing combinations of zidovudine plus didanosine or zalcitabine with zidovudine alone in HIV-infected individuals. Delta Coordinating Committee.
    Lancet (London, England), 1996, Aug-03, Volume: 348, Issue:9023

    Topics: Adolescent; Adult; Antiviral Agents; CD4 Lymphocyte Count; Didanosine; Disease Progression; Double-Blind Method; Drug Therapy, Combination; Female; Follow-Up Studies; HIV Infections; Humans; Male; Survival Analysis; Zalcitabine; Zidovudine

1996
Combination therapy with zidovudine, didanosine and saquinavir.
    Antiviral research, 1996, Volume: 29, Issue:1

    Topics: Antiviral Agents; Didanosine; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; Humans; Isoquinolines; Quinolines; Saquinavir; Zidovudine

1996
D4T nucleoside combinations for HIV.
    Antiviral research, 1996, Volume: 29, Issue:1

    Topics: Adult; Antiviral Agents; Didanosine; Drug Therapy, Combination; HIV Infections; Humans; Stavudine; Zidovudine

1996
A randomized trial (ISS 901) of switching to didanosine versus continued zidovudine after the diagnosis of AIDS.
    Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association, 1996, Aug-15, Volume: 12, Issue:5

    Topics: Acquired Immunodeficiency Syndrome; Adult; Antiviral Agents; Didanosine; Disease Progression; Drug Administration Schedule; Female; Humans; Male; Middle Aged; Zidovudine

1996
Development of resistance of zidovudine (ZDV) and didanosine (ddI) in HIV from patients in ZDV, ddI and alternating ZDV/ddI therapy.
    AIDS (London, England), 1996, Volume: 10, Issue:6

    Topics: Anti-HIV Agents; CD4-Positive T-Lymphocytes; Cells, Cultured; Didanosine; Drug Resistance; HIV Infections; HIV-1; Humans; Mutation; Zidovudine

1996
Effects of cytokines on antiviral pharmacokinetics: an alternative approach to assessment of drug interactions using bioequivalence guidelines.
    Antimicrobial agents and chemotherapy, 1996, Volume: 40, Issue:1

    Topics: Adult; Antiviral Agents; Cytokines; Didanosine; Drug Interactions; Drug Therapy, Combination; Female; HIV Infections; Humans; Interferon-alpha; Interleukin-2; Male; Reference Standards; Reference Values; Therapeutic Equivalency; Zidovudine

1996
Randomized, controlled phase I/II, trial of combination therapy with delavirdine (U-90152S) and conventional nucleosides in human immunodeficiency virus type 1-infected patients.
    Antimicrobial agents and chemotherapy, 1996, Volume: 40, Issue:7

    Topics: Adult; Anti-HIV Agents; Biological Availability; Delavirdine; Didanosine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Indoles; Male; Middle Aged; Piperazines; Reverse Transcriptase Inhibitors; Zidovudine

1996
A trial comparing nucleoside monotherapy with combination therapy in HIV-infected adults with CD4 cell counts from 200 to 500 per cubic millimeter. AIDS Clinical Trials Group Study 175 Study Team.
    The New England journal of medicine, 1996, Oct-10, Volume: 335, Issue:15

    Topics: Acquired Immunodeficiency Syndrome; Adult; Antiviral Agents; CD4 Lymphocyte Count; Didanosine; Disease Progression; Double-Blind Method; Drug Therapy, Combination; Female; HIV Infections; Humans; Male; Proportional Hazards Models; Treatment Outcome; Zidovudine

1996
The relation of virologic and immunologic markers to clinical outcomes after nucleoside therapy in HIV-infected adults with 200 to 500 CD4 cells per cubic millimeter. AIDS Clinical Trials Group Study 175 Virology Study Team.
    The New England journal of medicine, 1996, Oct-10, Volume: 335, Issue:15

    Topics: Adult; Antiviral Agents; CD4 Lymphocyte Count; Didanosine; Disease Progression; Drug Therapy, Combination; Female; HIV; HIV Infections; Humans; Male; Middle Aged; Multivariate Analysis; Phenotype; Proportional Hazards Models; RNA, Viral; Treatment Outcome; Virus Replication; Zidovudine

1996
Zidovudine alone or in combination with didanosine or zalcitabine in HIV-infected patients with the acquired immunodeficiency syndrome or fewer than 200 CD4 cells per cubic millimeter. Investigators for the Terry Beirn Community Programs for Clinical Rese
    The New England journal of medicine, 1996, Oct-10, Volume: 335, Issue:15

    Topics: Acquired Immunodeficiency Syndrome; Adult; Antiviral Agents; CD4 Lymphocyte Count; Didanosine; Disease Progression; Disease-Free Survival; Drug Therapy, Combination; Female; Humans; Male; Risk; Survival Analysis; Zalcitabine; Zidovudine

1996
The Alpha trial: European/Australian randomized double-blind trial of two doses of didanosine in zidovudine-intolerant patients with symptomatic HIV disease. Alpha International Coordinating Committee.
    AIDS (London, England), 1996, Volume: 10, Issue:8

    Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Didanosine; Disease Progression; Double-Blind Method; Drug Tolerance; Female; HIV Core Protein p24; HIV Infections; Humans; Male; Pancreatitis; Zidovudine

1996
Viral load, CD4 percentage, and delayed-type hypersensitivity in subjects receiving the HIV-1 immunogen and antiviral drug therapy.
    Journal of clinical immunology, 1996, Volume: 16, Issue:5

    Topics: AIDS Vaccines; CD4 Lymphocyte Count; Didanosine; Drug Therapy, Combination; HIV Envelope Protein gp120; HIV Infections; Hypersensitivity, Delayed; Immunotherapy, Active; Viral Load; Zidovudine

1996
Intrathecal immunoactivation in patients with HIV-1 infection is reduced by zidovudine but not by didanosine.
    Scandinavian journal of infectious diseases, 1996, Volume: 28, Issue:4

    Topics: Adult; Aged; Anti-HIV Agents; Biopterins; Didanosine; HIV Infections; HIV-1; Humans; Immunoglobulin G; Middle Aged; Neopterin; Zidovudine

1996
CD8+ lymphocyte responses to antiretroviral therapy of HIV infection.
    Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association, 1996, Dec-01, Volume: 13, Issue:4

    Topics: Acetamides; Acetophenones; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Didanosine; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; HIV Reverse Transcriptase; Humans; Lamivudine; Lymphocyte Count; Pyridines; Reverse Transcriptase Inhibitors; Ritonavir; Viral Load; Zalcitabine; Zidovudine

1996
AIDS therapy with two, three or four agent combinations, applied in short sequences, differing from each other by drug rotation. I. First of two parts: a phase I trial equivalent, concerning five virostatics: AZT, ddI, ddC, acriflavine and an ellipticine
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 1996, Volume: 50, Issue:5

    Topics: Acquired Immunodeficiency Syndrome; Acriflavine; Adult; Anti-Infective Agents; Antiviral Agents; CD4 Lymphocyte Count; Didanosine; Drug Therapy, Combination; Ellipticines; Female; Humans; Immunosuppressive Agents; Male; Middle Aged; Zalcitabine; Zidovudine

1996
Should we embrace new drugs with open arms? Experience from a community-based, open-arm, randomized clinical trial of combination antiretroviral therapy in advanced HIV disease.
    Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association, 1996, Dec-15, Volume: 13, Issue:5

    Topics: Adult; Anti-HIV Agents; British Columbia; Didanosine; Drug Therapy, Combination; Female; HIV Infections; Humans; Male; Middle Aged; Patient Selection; Practice Patterns, Physicians'; Prospective Studies; Zalcitabine; Zidovudine

1996
[Effect of treatment with nucleoside analogues in subjects with primary genotypic resistance to zidovudine].
    Medicina clinica, 1996, Nov-30, Volume: 107, Issue:19

    Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Didanosine; Drug Resistance; Drug Therapy, Combination; Genotype; HIV-1; Humans; Zalcitabine; Zidovudine

1996
Human immunodeficiency virus type 1 reverse transcriptase genotype and drug susceptibility changes in infected individuals receiving dideoxyinosine monotherapy for 1 to 2 years.
    Antimicrobial agents and chemotherapy, 1997, Volume: 41, Issue:4

    Topics: Anti-HIV Agents; Didanosine; Double-Blind Method; Drug Resistance, Microbial; Genotype; HIV Infections; HIV Reverse Transcriptase; Humans; Mutation; Polymerase Chain Reaction; Recombinant Proteins; Reverse Transcriptase Inhibitors; RNA, Viral; Zidovudine

1997
Phase I dose-escalation pharmacokinetics of AZT-P-ddI (IVX-E-59) in patients with human immunodeficiency virus.
    Journal of clinical pharmacology, 1997, Volume: 37, Issue:3

    Topics: Administration, Oral; Adult; Anti-HIV Agents; Biological Availability; Didanosine; Dideoxynucleotides; HIV Infections; Humans; Infusions, Intravenous; Male; Zidovudine

1997
Italian multicentre study of didanosine compassionate use in advanced HIV infection. Italian BMS-906 Study Group.
    European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 1997, Volume: 16, Issue:2

    Topics: Acquired Immunodeficiency Syndrome; Adolescent; Adult; Aged; AIDS Dementia Complex; Anti-HIV Agents; CD4 Lymphocyte Count; Didanosine; Disease Progression; Drug Resistance, Microbial; Female; HIV Infections; Humans; Immunocompromised Host; Italy; Male; Middle Aged; Multivariate Analysis; Pancreatitis; Treatment Outcome; Zidovudine

1997
Effect of combination therapy with zidovudine and didanosine on neuropsychological functioning in patients with symptomatic HIV disease: a comparison of simultaneous and alternating regimens.
    AIDS (London, England), 1997, Volume: 11, Issue:1

    Topics: Adult; AIDS Dementia Complex; Anti-HIV Agents; Didanosine; Drug Therapy, Combination; Female; Humans; Male; Neuropsychological Tests; Zidovudine

1997
Effects of a combination of zidovudine, didanosine, and lamivudine on primary human immunodeficiency virus type 1 infection.
    The Journal of infectious diseases, 1997, Volume: 175, Issue:5

    Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; CD4-CD8 Ratio; Didanosine; DNA, Viral; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Lamivudine; Lymphocytes; Male; Pilot Projects; Proviruses; RNA, Viral; Zidovudine

1997
Combination treatment with zidovudine, didanosine, and nevirapine in infants with human immunodeficiency virus type 1 infection.
    The New England journal of medicine, 1997, May-08, Volume: 336, Issue:19

    Topics: Administration, Oral; Anti-HIV Agents; CD4 Lymphocyte Count; Didanosine; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Infant; Infectious Disease Transmission, Vertical; Male; Nevirapine; Pyridines; RNA, Viral; Viral Load; Zidovudine

1997
Randomised trial of addition of lamivudine or lamivudine plus loviride to zidovudine-containing regimens for patients with HIV-1 infection: the CAESAR trial.
    Lancet (London, England), 1997, May-17, Volume: 349, Issue:9063

    Topics: Acetamides; Acetophenones; Acquired Immunodeficiency Syndrome; Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Didanosine; Disease Progression; Double-Blind Method; Drug Therapy, Combination; Female; Follow-Up Studies; Health Services; HIV-1; Humans; Lamivudine; Male; Middle Aged; Reverse Transcriptase Inhibitors; Zalcitabine; Zidovudine

1997
Additive or sequential nucleoside analogue therapy compared with continued zidovudine monotherapy in human immunodeficiency virus-infected patients with advanced disease does not prolong survival: an observational study.
    The Journal of infectious diseases, 1997, Volume: 175, Issue:6

    Topics: Adult; Age Factors; Anti-HIV Agents; Didanosine; Drug Administration Schedule; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Middle Aged; Prognosis; Proportional Hazards Models; Survival Rate; Treatment Outcome; Zalcitabine; Zidovudine

1997
Alternating treatment with didanosine and zidovudine versus either drug alone for the treatment of advanced HIV infection. The Alter Study. Nordic HIV Therapy Group.
    Scandinavian journal of infectious diseases, 1997, Volume: 29, Issue:2

    Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Didanosine; Drug Administration Schedule; Drug Therapy, Combination; Female; HIV Infections; Humans; Male; Middle Aged; Zidovudine

1997
Zidovudine, didanosine, or both as the initial treatment for symptomatic HIV-infected children. AIDS Clinical Trials Group (ACTG) Study 152 Team.
    The New England journal of medicine, 1997, Jun-12, Volume: 336, Issue:24

    Topics: Adolescent; Anti-HIV Agents; CD4 Lymphocyte Count; Child; Child, Preschool; Didanosine; Disease Progression; Disease-Free Survival; Double-Blind Method; Drug Therapy, Combination; Female; HIV Core Protein p24; HIV Infections; Humans; Infant; Male; Treatment Outcome; Zidovudine

1997
Monitoring plasma HIV-1 RNA levels in addition to CD4+ lymphocyte count improves assessment of antiretroviral therapeutic response. ACTG 241 Protocol Virology Substudy Team.
    Annals of internal medicine, 1997, Jun-15, Volume: 126, Issue:12

    Topics: Acquired Immunodeficiency Syndrome; Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Didanosine; Disease Progression; Drug Therapy, Combination; HIV-1; Humans; Monitoring, Physiologic; Nevirapine; Phenotype; Prospective Studies; Pyridines; RNA, Viral; Viral Load; Zidovudine

1997
A randomized trial (ISS 902) of didanosine versus zidovudine in previously untreated patients with mildly symptomatic human immunodeficiency virus infection.
    The Journal of infectious diseases, 1997, Volume: 175, Issue:2

    Topics: Acquired Immunodeficiency Syndrome; Adult; Anti-HIV Agents; Body Weight; CD4 Lymphocyte Count; Didanosine; Disease Progression; Female; HIV Core Protein p24; HIV Infections; Humans; Male; Risk; Zidovudine

1997
No therapeutic advantage from didanosine (ddI) and hydroxyurea versus ddI alone in patients with HIV infection.
    AIDS (London, England), 1997, Volume: 11, Issue:10

    Topics: CD4 Lymphocyte Count; Didanosine; Drug Therapy, Combination; HIV Infections; Humans; Hydroxyurea; RNA, Viral; Treatment Outcome; Viremia; Zidovudine

1997
HIV-1 viral load, phenotype, and resistance in a subset of drug-naive participants from the Delta trial. The National Virology Groups. Delta Virology Working Group and Coordinating Committee.
    Lancet (London, England), 1997, Oct-04, Volume: 350, Issue:9083

    Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Didanosine; Double-Blind Method; Drug Resistance, Microbial; Drug Therapy, Combination; Genes, pol; HIV Infections; HIV-1; Humans; Point Mutation; Prospective Studies; RNA, Viral; Viral Load; Zalcitabine; Zidovudine

1997
Quantification of HIV-1 proviral DNA by a standardized colorimetric PCR-based assay.
    Journal of medical virology, 1998, Volume: 54, Issue:1

    Topics: Adult; Anti-HIV Agents; Colorimetry; Didanosine; DNA, Viral; Evaluation Studies as Topic; Female; HIV-1; Humans; Indinavir; Lamivudine; Male; Polymerase Chain Reaction; Proviruses; Ritonavir; RNA, Viral; Transcription, Genetic; Zalcitabine; Zidovudine

1998
Interleukin-2 in combination with zidovudine and didanosine is able to maintain high levels of CD4 cells and undetectable HIV viraemia.
    AIDS (London, England), 1998, Jan-01, Volume: 12, Issue:1

    Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Didanosine; Drug Therapy, Combination; Female; HIV; HIV Infections; Humans; Interleukin-2; Leukocyte Common Antigens; Male; Pilot Projects; RNA, Viral; Viremia; Zidovudine

1998
A phase I/II study of the protease inhibitor ritonavir in children with human immunodeficiency virus infection.
    Pediatrics, 1998, Volume: 101, Issue:3 Pt 1

    Topics: Administration, Oral; Adolescent; Anti-HIV Agents; CD4 Lymphocyte Count; Child; Child, Preschool; Didanosine; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; Humans; Infant; Male; Ritonavir; Viral Load; Zidovudine

1998
[Effect of antiretroviral treatment on early electroencephalographic and otoneurologic manifestations in HIV infection and prognostic importance of verified perturbations].
    Neurophysiologie clinique = Clinical neurophysiology, 1997, Volume: 27, Issue:6

    Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Cross-Over Studies; Didanosine; Double-Blind Method; Electroencephalography; Follow-Up Studies; Hearing Tests; HIV-1; Humans; Male; Neurologic Examination; Prognosis; Reproducibility of Results; Zidovudine

1997
Pharmacokinetics of oral ganciclovir alone and in combination with zidovudine, didanosine, and probenecid in HIV-infected subjects.
    Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association, 1998, Mar-01, Volume: 17, Issue:3

    Topics: Administration, Oral; Adult; Anti-HIV Agents; Antiviral Agents; Area Under Curve; Didanosine; Drug Interactions; Female; Ganciclovir; Half-Life; HIV Infections; Humans; Male; Probenecid; Renal Agents; Zidovudine

1998
Changes in virologic markers as predictors of CD4 cell decline and progression of disease in human immunodeficiency virus type 1-infected adults treated with nucleosides. AIDS Clinical Trials Group Protocol 175 Team.
    The Journal of infectious diseases, 1998, Volume: 177, Issue:3

    Topics: Adult; Anti-HIV Agents; Biomarkers; CD4 Lymphocyte Count; Didanosine; Dideoxynucleosides; Disease Progression; HIV Core Protein p24; HIV Infections; HIV-1; Humans; Leukocytes, Mononuclear; Multivariate Analysis; Prognosis; Reverse Transcriptase Inhibitors; RNA, Viral; Zalcitabine; Zidovudine

1998
Antiviral effect of double and triple drug combinations amongst HIV-infected adults: lessons from the implementation of viral load-driven antiretroviral therapy.
    AIDS (London, England), 1998, Feb-12, Volume: 12, Issue:3

    Topics: Adult; Anti-HIV Agents; Cohort Studies; Didanosine; Drug Therapy, Combination; Female; HIV Infections; Humans; Lamivudine; Male; Multivariate Analysis; Stavudine; Viral Load; Zalcitabine; Zidovudine

1998
The effects of lamivudine treatment on HIV-1 disease progression are highly correlated with plasma HIV-1 RNA and CD4 cell count.
    AIDS (London, England), 1998, Mar-26, Volume: 12, Issue:5

    Topics: Acetamides; Acetophenones; Acquired Immunodeficiency Syndrome; Adult; Aged; Anti-HIV Agents; CD4 Lymphocyte Count; Didanosine; Disease Progression; Double-Blind Method; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Middle Aged; Multivariate Analysis; Proportional Hazards Models; RNA, Viral; Treatment Outcome; Viral Load; Zalcitabine; Zidovudine

1998
A randomized, double-blind trial comparing combinations of nevirapine, didanosine, and zidovudine for HIV-infected patients: the INCAS Trial. Italy, The Netherlands, Canada and Australia Study.
    JAMA, 1998, Mar-25, Volume: 279, Issue:12

    Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Didanosine; Disease Progression; Double-Blind Method; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Male; Middle Aged; Nevirapine; RNA, Viral; Viral Load; Zidovudine

1998
Phenotypic variability of lymphocyte populations in peripheral blood and lymph nodes from HIV-infected individuals and the impact of antiretroviral therapy. DATRI 003 Study Group. Division of AIDS Treatment Research Initiative.
    AIDS research and human retroviruses, 1998, Mar-20, Volume: 14, Issue:5

    Topics: Anti-HIV Agents; B-Lymphocytes; Didanosine; HIV Seropositivity; Humans; Immunophenotyping; Lymph Nodes; Lymphocyte Count; Lymphocyte Subsets; Prospective Studies; T-Lymphocytes; Zidovudine

1998
[Efficacy of combining zidovudine plus didanosine in patients with and without previous exposure to zidovudine].
    Anales de medicina interna (Madrid, Spain : 1984), 1998, Volume: 15, Issue:3

    Topics: Adult; CD4 Lymphocyte Count; Didanosine; Drug Therapy, Combination; Female; HIV Infections; Humans; Male; Viral Load; Zidovudine

1998
Cellular proviral HIV type 1 DNA load persists after long-term RT-inhibitor therapy in HIV type 1 infected persons.
    AIDS research and human retroviruses, 1998, Aug-10, Volume: 14, Issue:12

    Topics: Anti-HIV Agents; Base Sequence; Didanosine; DNA Primers; DNA, Viral; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Proviruses; Reverse Transcriptase Inhibitors; Viral Load; Zalcitabine; Zidovudine

1998
Predictive factors influencing peak viral load drop in response to nucleoside reverse transcriptase inhibitors in antiretroviral-naive HIV-1-infected patients.
    Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association, 1998, Sep-01, Volume: 19, Issue:1

    Topics: Adult; Analysis of Variance; Anti-HIV Agents; Didanosine; Drug Therapy, Combination; Female; Giant Cells; HIV Infections; HIV-1; Humans; Linear Models; Male; Middle Aged; Multivariate Analysis; Phenotype; Probability; Reverse Transcriptase Inhibitors; Risk Factors; Time Factors; Viral Load; Zalcitabine; Zidovudine

1998
Suppression of plasma viral load below 20 copies/ml is required to achieve a long-term response to therapy.
    AIDS (London, England), 1998, Sep-10, Volume: 12, Issue:13

    Topics: Anti-HIV Agents; Australia; Canada; CD4 Lymphocyte Count; Didanosine; Double-Blind Method; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Italy; Netherlands; Nevirapine; Reverse Transcriptase Inhibitors; RNA, Viral; Viral Load; Zidovudine

1998
A randomized study of combined zidovudine-lamivudine versus didanosine monotherapy in children with symptomatic therapy-naive HIV-1 infection. The Pediatric AIDS Clinical Trials Group Protocol 300 Study Team.
    The Journal of pediatrics, 1998, Volume: 133, Issue:4

    Topics: Adolescent; Anti-HIV Agents; CD4 Antigens; Child; Child, Preschool; Didanosine; Disease Progression; Double-Blind Method; Drug Therapy, Combination; Female; Follow-Up Studies; HIV Infections; HIV-1; Humans; Lamivudine; Male; Neurodegenerative Diseases; Polymerase Chain Reaction; RNA, Viral; Survival Rate; Zidovudine

1998
A randomized double-blind trial of the addition of lamivudine or matching placebo to current nucleoside analogue reverse transcriptase inhibitor therapy in HIV-infected children: the PENTA-4 trial. Paediatric European Network for Treatment of AIDS.
    AIDS (London, England), 1998, Oct-01, Volume: 12, Issue:14

    Topics: Adolescent; Anti-HIV Agents; CD4 Lymphocyte Count; Child; Child, Preschool; Didanosine; Double-Blind Method; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Infant; Lamivudine; Male; Reverse Transcriptase Inhibitors; RNA, Viral; Time Factors; Treatment Outcome; Viral Load; Zalcitabine; Zidovudine

1998
Individual prognoses of long-term responses to antiretroviral treatment based on virological, immunological and pharmacological parameters measured during the first week under therapy.
    AIDS (London, England), 1998, Oct-22, Volume: 12, Issue:15

    Topics: Adolescent; Anti-HIV Agents; CD4 Lymphocyte Count; Child; Child, Preschool; Didanosine; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Prognosis; Reverse Transcriptase Inhibitors; Ritonavir; RNA, Viral; Viral Load; Zidovudine

1998
A trial comparing nucleoside monotherapy with sequential therapy with 3 drugs in HIV-infected patients.
    Scandinavian journal of infectious diseases, 1998, Volume: 30, Issue:4

    Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Didanosine; Drug Therapy, Combination; Female; HIV Infections; Humans; Male; Reverse Transcriptase Inhibitors; Treatment Outcome; Zalcitabine; Zidovudine

1998
A randomized, controlled, double-blind study comparing the survival benefit of four different reverse transcriptase inhibitor therapies (three-drug, two-drug, and alternating drug) for the treatment of advanced AIDS. AIDS Clinical Trial Group 193A Study T
    Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association, 1998, Dec-01, Volume: 19, Issue:4

    Topics: Acquired Immunodeficiency Syndrome; Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Didanosine; Disease-Free Survival; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; HIV; Humans; Male; Nevirapine; Placebos; Reverse Transcriptase Inhibitors; RNA, Viral; Survival Rate; Time Factors; Zalcitabine; Zidovudine

1998
Characterizing patterns of drug-taking behavior with a multiple drug regimen in an AIDS clinical trial.
    AIDS (London, England), 1998, Dec-03, Volume: 12, Issue:17

    Topics: Acquired Immunodeficiency Syndrome; Adult; Aged; Anti-HIV Agents; Didanosine; Double-Blind Method; Drug Administration Schedule; Female; Humans; Male; Middle Aged; Patient Compliance; Reverse Transcriptase Inhibitors; Time Factors; Zalcitabine; Zidovudine

1998
The extent of non-adherence in a large AIDS clinical trial using plasma dideoxynucleoside concentrations as a marker.
    AIDS (London, England), 1998, Dec-03, Volume: 12, Issue:17

    Topics: Acquired Immunodeficiency Syndrome; Adolescent; Adult; Aged; Anti-HIV Agents; Didanosine; Double-Blind Method; Drug Administration Schedule; Female; Humans; Male; Middle Aged; Patient Compliance; Reverse Transcriptase Inhibitors; Zalcitabine; Zidovudine

1998
Population pharmacokinetics of nevirapine, zidovudine, and didanosine in human immunodeficiency virus-infected patients. The National Institute of Allergy and Infectious Diseases AIDS Clinical Trials Group Protocol 241 Investigators.
    Antimicrobial agents and chemotherapy, 1999, Volume: 43, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Adolescent; Adult; Anti-HIV Agents; Didanosine; Double-Blind Method; Drug Therapy, Combination; Female; HIV Infections; Humans; Male; Middle Aged; Models, Biological; Nevirapine; Zidovudine

1999
Zidovudine therapy and HIV type 1 mutations in children with symptomatic HIV type 1 infection: effect of switching to didanosine or zidovudine plus didanosine therapy. Italian Multicenter Study Group on HIV Mutations in Children.
    AIDS research and human retroviruses, 1998, Dec-20, Volume: 14, Issue:18

    Topics: Anti-HIV Agents; Base Sequence; Child; Codon; Didanosine; DNA Primers; Drug Therapy, Combination; Genotype; HIV Infections; HIV-1; Humans; Mutation; Reverse Transcriptase Inhibitors; Zidovudine

1998
A randomized, double-blind trial on the use of a triple combination including nevirapine, a nonnucleoside reverse transcriptase HIV inhibitor, in antiretroviral-naive patients with advanced disease.
    Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association, 1999, Jan-01, Volume: 20, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Didanosine; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Nevirapine; Zidovudine

1999
Virologic and immunologic response to nucleoside reverse-transcriptase inhibitor therapy among human immunodeficiency virus-infected infants and children.
    The Journal of infectious diseases, 1999, Volume: 179, Issue:3

    Topics: Adolescent; Anti-HIV Agents; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; Child; Child, Preschool; Didanosine; Drug Therapy, Combination; HIV Infections; HIV Reverse Transcriptase; Humans; Infant; Reverse Transcriptase Inhibitors; RNA, Viral; Time Factors; Zidovudine

1999
An evaluation of HIV RNA and CD4 cell count as surrogates for clinical outcome. Delta Coordinating Committee and Virology Group.
    AIDS (London, England), 1999, Apr-01, Volume: 13, Issue:5

    Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Didanosine; Double-Blind Method; HIV Infections; HIV-1; Humans; Reverse Transcriptase Inhibitors; RNA, Viral; Treatment Outcome; Viral Load; Zidovudine

1999
HIV-1 RNA response to antiretroviral treatment in 1280 participants in the Delta Trial: an extended virology study.
    AIDS (London, England), 1999, Jan-14, Volume: 13, Issue:1

    Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Didanosine; Double-Blind Method; Female; HIV Infections; HIV-1; Humans; Male; Predictive Value of Tests; Reverse Transcriptase Inhibitors; RNA, Viral; Time Factors; Viral Load; Zalcitabine; Zidovudine

1999
Recombinant human gamma interferon in human immunodeficiency virus-infected children: safety, CD4(+)-lymphocyte count, viral load, and neutrophil function (AIDS Clinical Trials Group Protocol 211).
    Clinical and diagnostic laboratory immunology, 1999, Volume: 6, Issue:3

    Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Child; Child, Preschool; Didanosine; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Infant; Interferon-gamma; Male; Neutrophils; Recombinant Proteins; Reverse Transcriptase Inhibitors; Viral Load; Zidovudine

1999
Immunoreconstitution after ritonavir therapy in children with human immunodeficiency virus infection involves multiple lymphocyte lineages.
    The Journal of pediatrics, 1999, Volume: 134, Issue:5

    Topics: Adolescent; Anti-HIV Agents; CD4-CD8 Ratio; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Child; Child, Preschool; Didanosine; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; Humans; Immunophenotyping; Infant; Leukocyte Common Antigens; Lymphocyte Subsets; Ritonavir; Viral Load; Zidovudine

1999
[Response of fetal macrophages in the placenta of pregnant HIV-positive patients with and without antiretroviral treatment].
    Ginecologia y obstetricia de Mexico, 1999, Volume: 67

    Topics: Antiviral Agents; Didanosine; Female; HIV Infections; HIV Seropositivity; Humans; Macrophages; Pregnancy; Pregnancy Complications, Infectious; Retroviridae; Zidovudine

1999
Comparison of subcutaneous and intravenous interleukin-2 in asymptomatic HIV-1 infection: a randomised controlled trial. ANRS 048 study group.
    Lancet (London, England), 1999, Jun-05, Volume: 353, Issue:9168

    Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; CD4-CD8 Ratio; Didanosine; Female; Follow-Up Studies; HIV Infections; HIV-1; Humans; Infusions, Intravenous; Injections, Subcutaneous; Interleukin-2; Male; Time Factors; Zidovudine

1999
The ALBI trial: a randomized controlled trial comparing stavudine plus didanosine with zidovudine plus lamivudine and a regimen alternating both combinations in previously untreated patients infected with human immunodeficiency virus.
    The Journal of infectious diseases, 1999, Volume: 180, Issue:2

    Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Didanosine; Drug Administration Schedule; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Reverse Transcriptase Inhibitors; RNA, Viral; Stavudine; Treatment Outcome; Viremia; Zidovudine

1999
Lamivudine in combination with zidovudine, stavudine, or didanosine in patients with HIV-1 infection. A randomized, double-blind, placebo-controlled trial. National Institute of Allergy and Infectious Disease AIDS Clinical Trials Group Protocol 306 Invest
    AIDS (London, England), 1999, Apr-16, Volume: 13, Issue:6

    Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Didanosine; Double-Blind Method; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Reverse Transcriptase Inhibitors; RNA, Viral; Stavudine; Viral Load; Zidovudine

1999
Combining mortality and longitudinal measures in clinical trials.
    Statistics in medicine, 1999, Jun-15, Volume: 18, Issue:11

    Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Anti-Infective Agents; Antifungal Agents; Candidiasis; Child; Child, Preschool; Clinical Trials as Topic; Clotrimazole; Dapsone; Didanosine; Drug Therapy, Combination; Fluconazole; Head; Humans; Longitudinal Studies; Pentamidine; Pneumonia, Pneumocystis; Statistics, Nonparametric; Treatment Outcome; Trimethoprim, Sulfamethoxazole Drug Combination; Zidovudine

1999
Efficacy and safety of delavirdine mesylate with zidovudine and didanosine compared with two-drug combinations of these agents in persons with HIV disease with CD4 counts of 100 to 500 cells/mm3 (ACTG 261). ACTG 261 Team.
    Journal of acquired immune deficiency syndromes (1999), 1999, Aug-01, Volume: 21, Issue:4

    Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Delavirdine; Didanosine; Double-Blind Method; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Male; Reverse Transcriptase Inhibitors; RNA, Viral; Safety; Zidovudine

1999
Preliminary evaluation of human immunodeficiency virus type 1 (HIV-1) immunogen in children with HIV-1 infection.
    The Journal of infectious diseases, 1999, Volume: 180, Issue:3

    Topics: Adolescent; AIDS Vaccines; Anti-HIV Agents; Child; Child, Preschool; Combined Modality Therapy; Didanosine; Dose-Response Relationship, Drug; Double-Blind Method; Female; HIV Infections; HIV-1; Humans; Infant; Male; RNA, Viral; Safety; Time Factors; Zidovudine

1999
Cerebrospinal fluid human immunodeficiency virus type 1 (HIV-1) suppression and efavirenz drug concentrations in HIV-1-infected patients receiving combination therapy.
    The Journal of infectious diseases, 1999, Volume: 180, Issue:3

    Topics: Acquired Immunodeficiency Syndrome; Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Didanosine; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Indinavir; Lamivudine; Oxazines; Viral Load; Zidovudine

1999
Relation of peripheral neuropathy to HIV treatment in four randomized clinical trials including didanosine.
    Clinical therapeutics, 1999, Volume: 21, Issue:7

    Topics: Adolescent; Adult; Aged; Anti-HIV Agents; CD4 Lymphocyte Count; Child, Preschool; Data Collection; Didanosine; Dose-Response Relationship, Drug; Double-Blind Method; Drug Interactions; Female; Humans; Male; Middle Aged; Peripheral Nervous System Diseases; Polypharmacy; Randomized Controlled Trials as Topic; Risk Factors; Time Factors; Zalcitabine; Zidovudine

1999
Neurologic, neurocognitive, and brain growth outcomes in human immunodeficiency virus-infected children receiving different nucleoside antiretroviral regimens. Pediatric AIDS Clinical Trials Group 152 Study Team.
    Pediatrics, 1999, Volume: 104, Issue:3

    Topics: Adolescent; Analysis of Variance; Anti-HIV Agents; Brain; Central Nervous System Diseases; Child; Child, Preschool; Cognition; Didanosine; Double-Blind Method; Drug Therapy, Combination; Female; HIV Infections; Humans; Infant; Intelligence Tests; Male; Motor Skills; Reverse Transcriptase Inhibitors; Zidovudine

1999
Sequence clusters in human immunodeficiency virus type 1 reverse transcriptase are associated with subsequent virological response to antiretroviral therapy.
    The Journal of infectious diseases, 1999, Volume: 180, Issue:4

    Topics: Acquired Immunodeficiency Syndrome; Amino Acid Sequence; Anti-HIV Agents; Didanosine; Drug Therapy, Combination; Evolution, Molecular; HIV Reverse Transcriptase; HIV-1; Humans; Molecular Sequence Data; Nevirapine; Sequence Alignment; Time Factors; Viral Load; Zidovudine

1999
Long-term effects of antiretroviral combination therapy on HIV type 1 DNA levels.
    AIDS research and human retroviruses, 1999, Sep-20, Volume: 15, Issue:14

    Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; CD8-Positive T-Lymphocytes; Data Interpretation, Statistical; Didanosine; DNA, Viral; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Middle Aged; Polymerase Chain Reaction; RNA, Viral; Stavudine; Time Factors; Zidovudine

1999
Rapid detection of the HIV type 1 reverse transcriptase codon T215Y by reverse transcription-polymerase chain reaction with fluorogenic probes.
    AIDS research and human retroviruses, 1999, Sep-20, Volume: 15, Issue:14

    Topics: Anti-HIV Agents; Child; Child, Preschool; Codon; Didanosine; DNA Mutational Analysis; Drug Resistance, Microbial; Drug Resistance, Multiple; Fluorescent Dyes; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Point Mutation; Retrospective Studies; Reverse Transcriptase Polymerase Chain Reaction; Zidovudine

1999
Preliminary experiences with triple therapy including nelfinavir and two reverse transcriptase inhibitors in previously untreated HIV-infected children.
    AIDS (London, England), 1999, Sep-10, Volume: 13, Issue:13

    Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Child; Child, Preschool; Didanosine; Drug Therapy, Combination; Female; HIV Infections; Humans; Infant; Lamivudine; Male; Nelfinavir; Prospective Studies; Reverse Transcriptase Inhibitors; Stavudine; Viral Load; Zidovudine

1999
Mutations conferring resistance to zidovudine diminish the antiviral effect of stavudine plus didanosine.
    Journal of medical virology, 1999, Volume: 59, Issue:4

    Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Didanosine; Drug Resistance; Drug Therapy, Combination; Female; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Male; Mutation; Pilot Projects; Reverse Transcriptase Inhibitors; RNA, Viral; Stavudine; Zidovudine

1999
Combined antiviral therapy reduces HIV-1 plasma load and improves CD4 counts but does not interfere with ongoing lymphocyte apoptosis.
    Immunopharmacology and immunotoxicology, 1999, Volume: 21, Issue:4

    Topics: Adult; Anti-HIV Agents; Apoptosis; Caspase 1; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Ceramides; Didanosine; Drug Therapy, Combination; fas Receptor; HIV Infections; HIV-1; Humans; Male; Mitochondria; Viral Load; Viremia; Zidovudine

1999
A randomized study comparing triple versus double antiretroviral therapy or no treatment in HIV-1-infected patients in very early stage disease: the Spanish Earth-1 study.
    AIDS (London, England), 1999, Dec-03, Volume: 13, Issue:17

    Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; CD4-CD8 Ratio; Didanosine; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Palatine Tonsil; Ritonavir; RNA, Viral; Spain; Stavudine; Viremia; Zalcitabine; Zidovudine

1999
Patterns of resistance mutations selected by treatment of human immunodeficiency virus type 1 infection with zidovudine, didanosine, and nevirapine.
    The Journal of infectious diseases, 2000, Volume: 181, Issue:3

    Topics: Acquired Immunodeficiency Syndrome; Codon; Didanosine; Double-Blind Method; Drug Resistance; Drug Therapy, Combination; HIV Reverse Transcriptase; HIV-1; Humans; Mutation; Nevirapine; Polymerase Chain Reaction; Zidovudine

2000
Meta-analysis of two randomized controlled trials comparing combined zidovudine and didanosine therapy with combined zidovudine, didanosine, and nevirapine therapy in patients with HIV. INCAS study team.
    Journal of acquired immune deficiency syndromes (1999), 1999, Nov-01, Volume: 22, Issue:3

    Topics: Adult; Didanosine; Drug Therapy, Combination; Female; HIV Infections; Humans; Male; Middle Aged; Multivariate Analysis; Nevirapine; Proportional Hazards Models; Viral Load; Zidovudine

1999
A randomized, controlled, phase II trial comparing escalating doses of subcutaneous interleukin-2 plus antiretrovirals versus antiretrovirals alone in human immunodeficiency virus-infected patients with CD4+ cell counts >/=350/mm3.
    The Journal of infectious diseases, 2000, Volume: 181, Issue:5

    Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; CD8-Positive T-Lymphocytes; Didanosine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; HIV Infections; Humans; Indinavir; Injections, Subcutaneous; Interleukin-2; Lamivudine; Lymphocyte Count; Male; Nelfinavir; Nevirapine; Ritonavir; RNA, Viral; Saquinavir; Stavudine; Zalcitabine; Zidovudine

2000
Dual nucleoside regimens in nonadvanced HIV infection: prospective follow-up of 130 patients, Aquitaine Cohort, 1996 to 1998. Groupe d'Epidémiologie Clinique du SIDA en Aquitaine (GECSA).
    Journal of acquired immune deficiency syndromes (1999), 2000, Mar-01, Volume: 23, Issue:3

    Topics: AIDS-Related Opportunistic Infections; Anti-HIV Agents; CD4 Lymphocyte Count; Cohort Studies; Didanosine; Drug Therapy, Combination; Follow-Up Studies; HIV Infections; HIV-1; Humans; Lamivudine; Multivariate Analysis; Prospective Studies; Reverse Transcriptase Inhibitors; RNA, Viral; Stavudine; Treatment Outcome; Zalcitabine; Zidovudine

2000
Effect of two different combinations of antiretrovirals (AZT+ddI and AZT+3TC) on cytokine production and apoptosis in asymptomatic HIV infection.
    Antiviral research, 2000, Volume: 46, Issue:3

    Topics: Anti-HIV Agents; Apoptosis; CD4 Lymphocyte Count; CD4-CD8 Ratio; Cytokines; Didanosine; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Lamivudine; Leukocytes, Mononuclear; Prospective Studies; Reverse Transcriptase Inhibitors; Th1 Cells; Viremia; Zidovudine

2000
A randomised, open-label comparison of three highly active antiretroviral therapy regimens including two nucleoside analogues and indinavir for previously untreated HIV-1 infection: the OzCombo1 study.
    AIDS (London, England), 2000, Jun-16, Volume: 14, Issue:9

    Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Australia; CD4 Lymphocyte Count; Didanosine; Female; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Male; Stavudine; Viral Load; Zidovudine

2000
The CCR5Delta32 allele slows disease progression of human immunodeficiency virus-1-infected children receiving antiretroviral treatment.
    The Journal of infectious diseases, 2000, Volume: 182, Issue:2

    Topics: Alleles; Anti-HIV Agents; Child, Preschool; Clinical Trials as Topic; Didanosine; Disease Progression; Disease-Free Survival; Ethnicity; Gene Frequency; HIV Infections; HIV-1; Humans; Racial Groups; Receptors, CCR5; Sequence Deletion; Zidovudine

2000
Plasma HIV-1 copy number and in vitro infectivity of plasma prior to and during combination antiretroviral treatment.
    Antiviral research, 2000, Volume: 47, Issue:3

    Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Didanosine; Double-Blind Method; Drug Therapy, Combination; Giant Cells; HIV Infections; HIV-1; Humans; Nevirapine; RNA, Viral; Viral Load; Zidovudine

2000
A comparison of stavudine, didanosine and indinavir with zidovudine, lamivudine and indinavir for the initial treatment of HIV-1 infected individuals: selection of thymidine analog regimen therapy (START II).
    AIDS (London, England), 2000, Jul-28, Volume: 14, Issue:11

    Topics: Adolescent; Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Didanosine; Dideoxynucleosides; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Indinavir; Lamivudine; Male; Reverse Transcriptase Inhibitors; Stavudine; Thymidine; Viral Load; Zidovudine

2000
Differences between women and men in adverse events and CD4+ responses to nucleoside analogue therapy for HIV infection. The Aids Clinical Trials Group 175 Team.
    Journal of acquired immune deficiency syndromes (1999), 2000, Aug-01, Volume: 24, Issue:4

    Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Didanosine; Double-Blind Method; Female; HIV Infections; Humans; Liver; Male; Nucleosides; Prospective Studies; Sex Characteristics; Zalcitabine; Zidovudine

2000
Effect of lamivudine in HIV-infected persons with prior exposure to zidovudine/didanosine or zidovudine/zalcitabine.
    AIDS research and human retroviruses, 2000, Sep-20, Volume: 16, Issue:14

    Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Didanosine; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Reverse Transcriptase Inhibitors; RNA, Viral; Treatment Outcome; Zalcitabine; Zidovudine

2000
Didanosine dosed once daily is equivalent to twice daily dosing for patients on double or triple combination antiretroviral therapy. The AI454-147 Team.
    Journal of acquired immune deficiency syndromes (1999), 2000, Aug-15, Volume: 24, Issue:5

    Topics: Adult; Anti-HIV Agents; Didanosine; Drug Administration Schedule; Drug Therapy, Combination; Female; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Male; Middle Aged; Mutation; Reverse Transcriptase Inhibitors; RNA, Viral; Stavudine; Treatment Outcome; Zidovudine

2000
Predicting HIV disease progression in children using measures of neuropsychological and neurological functioning. Pediatric AIDS clinical trials 152 study team.
    Pediatrics, 2000, Volume: 106, Issue:6

    Topics: Acquired Immunodeficiency Syndrome; Adolescent; AIDS Dementia Complex; Anti-HIV Agents; Brain; CD4 Lymphocyte Count; Child; Child, Preschool; Didanosine; Disease Progression; Double-Blind Method; Drug Therapy, Combination; Female; HIV-1; Humans; Infant; Intelligence Tests; Male; Neurologic Examination; Neuropsychological Tests; Predictive Value of Tests; Radiography; Regression Analysis; RNA, Viral; Zidovudine

2000
Quality of life outcomes of combination zidovudine- didanosine-nevirapine and zidovudine-didanosine for antiretroviral-naive advanced HIV-infected patients.
    AIDS (London, England), 2000, Nov-10, Volume: 14, Issue:16

    Topics: Adult; Anti-HIV Agents; Didanosine; Double-Blind Method; Drug Therapy, Combination; Female; HIV Infections; Humans; Male; Nevirapine; Quality of Life; Reverse Transcriptase Inhibitors; Treatment Outcome; Zidovudine

2000
Virologic and CD4 cell response to zidovudine or zidovudine and lamivudine following didanosine treatment of human immunodeficiency virus infection.
    AIDS research and human retroviruses, 2001, Feb-10, Volume: 17, Issue:3

    Topics: Adult; CD4 Lymphocyte Count; Didanosine; Double-Blind Method; Drug Therapy, Combination; Female; HIV Infections; Humans; Lamivudine; Male; Middle Aged; Reverse Transcriptase Inhibitors; RNA, Viral; Treatment Outcome; Zidovudine

2001
Lack of an effect of azithromycin on the disposition of zidovudine and dideoxyinosine in HIV-infected patients.
    Journal of clinical pharmacology, 2001, Volume: 41, Issue:2

    Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Anti-HIV Agents; Azithromycin; Didanosine; Drug Interactions; Female; HIV Infections; Humans; Male; Middle Aged; Zidovudine

2001
Therapeutic effects of nucleoside analogues on psychomotor slowing in HIV infection.
    AIDS (London, England), 2001, Mar-09, Volume: 15, Issue:4

    Topics: Adult; Anti-HIV Agents; Central Nervous System Diseases; Didanosine; Drug Therapy, Combination; Female; HIV Infections; HIV Seropositivity; HIV-1; Humans; Lamivudine; Male; Middle Aged; Motor Skills; Stavudine; Zalcitabine; Zidovudine

2001
An open-label randomized trial to evaluate different therapeutic strategies of combination therapy in HIV-1 infection: design, rationale, and methods of the initio trial.
    Controlled clinical trials, 2001, Volume: 22, Issue:2

    Topics: Adult; Didanosine; Dideoxynucleosides; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Middle Aged; Nelfinavir; Patient Selection; Randomized Controlled Trials as Topic; Research Design; Ritonavir; Sample Size; Saquinavir; Stavudine; Zidovudine

2001
A pilot case-control study of zidovudine compared with zidovudine plus didanosine in patients with advanced HIV-1 disease and no previous experience with antiretrovirals.
    Antiviral therapy, 1996, Volume: 1, Issue:2

    Topics: Adult; Anti-HIV Agents; Case-Control Studies; CD4 Lymphocyte Count; Codon; Didanosine; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Male; Multivariate Analysis; Mutation; Nausea; Neutropenia; Pilot Projects; RNA, Viral; Survival Analysis; Zidovudine

1996
The impact of zidovudine compared with didanosine on health status and functioning in persons with advanced HIV infection and a varying duration of prior zidovudine therapy. AIDS Clinical Trials Group 116/117 Study Group.
    Antiviral therapy, 1996, Volume: 1, Issue:1

    Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Didanosine; Female; HIV Infections; Humans; Male; Severity of Illness Index; Sickness Impact Profile; Survival Analysis; Time Factors; Treatment Outcome; Zidovudine

1996
Hydroxyurea and didanosine is a more potent combination than hydroxyurea and zidovudine.
    Antiviral therapy, 1997, Volume: 2, Issue:1

    Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Didanosine; Drug Therapy, Combination; Female; HIV Infections; Humans; Hydroxyurea; Male; Middle Aged; Zidovudine

1997
Once versus twice daily administration of didanosine in children with symptomatic HIV-associated disease who were intolerant to or clinically deteriorated on zidovudine. The Italian Pediatric Collaborative Study Group on Didanosine.
    Antiviral therapy, 1997, Volume: 2, Issue:1

    Topics: Adolescent; Anti-HIV Agents; CD4 Lymphocyte Count; Child; Child, Preschool; Didanosine; Drug Administration Schedule; Female; HIV Infections; Humans; Infant; Male; Zidovudine

1997
Research study of combination AIDS therapies underway.
    AIDS patient care and STDs, 1996, Volume: 10, Issue:1

    Topics: Anti-HIV Agents; Didanosine; Drug Therapy, Combination; Humans; Lamivudine; Nevirapine; Pyridines; Zidovudine

1996
Final CESARE trial results show continued clinical and survival benefit.
    AIDS patient care and STDs, 1997, Volume: 11, Issue:2

    Topics: Acetamides; Acetophenones; Anti-HIV Agents; Antiviral Agents; CD4 Lymphocyte Count; Controlled Clinical Trials as Topic; Didanosine; Drug Therapy, Combination; HIV Infections; Humans; Lamivudine; Survival Rate; Zalcitabine; Zidovudine

1997
Viramune triple combo reduces viral load below limit of detection.
    AIDS patient care and STDs, 1997, Volume: 11, Issue:6

    Topics: Adult; Anti-HIV Agents; Didanosine; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Male; Nevirapine; Randomized Controlled Trials as Topic; Viral Load; Zidovudine

1997
AZT: pediatric study changed after worse monotherapy survival.
    AIDS treatment news, 1995, Feb-17, Issue:no 217

    Topics: Adolescent; Child; Child, Preschool; Didanosine; Drug Therapy, Combination; HIV Infections; Humans; Infant; Survival Analysis; Zidovudine

1995
Pediatrics clinical trial drops AZT-alone arm.
    Common factor (Stoughton, Mass.), 1995, Issue:no 10

    Topics: Adolescent; Child; Child, Preschool; Didanosine; Drug Therapy, Combination; Humans; Infant; Treatment Failure; Zidovudine

1995
Major study shows AZT monotherapy inferior.
    AIDS treatment news, 1995, Sep-29, Issue:no 231

    Topics: CD4 Lymphocyte Count; Clinical Trials as Topic; Didanosine; Drug Therapy, Combination; HIV; HIV Infections; Humans; Randomized Controlled Trials as Topic; Zalcitabine; Zidovudine

1995
New double vs. triple antiviral combination study, CD4 200-500, no prior treatment.
    AIDS treatment news, 1995, Dec-01, Issue:no 236

    Topics: Antiviral Agents; CD4 Lymphocyte Count; Didanosine; Drug Therapy, Combination; HIV Infections; Humans; Lamivudine; Nevirapine; Pyridines; Reverse Transcriptase Inhibitors; Zalcitabine; Zidovudine

1995
Antiretroviral combination treatment prolongs life in people with HIV/AIDS.
    AmFAR report, 1996

    Topics: Antiviral Agents; Clinical Trials as Topic; Didanosine; Drug Resistance, Microbial; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; Humans; Lamivudine; Multicenter Studies as Topic; Randomized Controlled Trials as Topic; Reverse Transcriptase Inhibitors; Zalcitabine; Zidovudine

1996
CPCRA 007: preliminary results of combination antiretroviral study.
    NIAID AIDS agenda, 1996

    Topics: Antiviral Agents; Didanosine; Drug Therapy, Combination; HIV Infections; Humans; Randomized Controlled Trials as Topic; Zalcitabine; Zidovudine

1996
Major pediatric study stopped early: combination treatment better.
    AIDS treatment news, 1997, Jul-04, Issue:No 274

    Topics: Anti-HIV Agents; Child; Didanosine; Drug Therapy, Combination; HIV Infections; Humans; Lamivudine; Zidovudine

1997
Combination therapies improve outlook for children with HIV disease.
    NIAID AIDS agenda, 1997

    Topics: Adolescent; Anti-HIV Agents; Child; Child, Preschool; Didanosine; Drug Therapy, Combination; HIV Infections; Humans; Infant; Lamivudine; Zidovudine

1997
Maintaining a low viral load with Nevirapine?
    TreatmentUpdate, 1998, Volume: 10, Issue:10

    Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Didanosine; Drug Resistance, Microbial; Drug Therapy, Combination; HIV Infections; Humans; Nevirapine; Randomized Controlled Trials as Topic; Reverse Transcriptase Inhibitors; Viral Load; Zidovudine

1998
Virus sidesteps convergent therapy.
    GMHC treatment issues : the Gay Men's Health Crisis newsletter of experimental AIDS therapies, 1995, Volume: 9, Issue:1

    Topics: Antiviral Agents; CD4 Lymphocyte Count; Didanosine; Drug Therapy, Combination; HIV Infections; Humans; Nevirapine; Pyridines; Zidovudine

1995
A randomized, open-label, comparative trial of zidovudine plus lamivudine versus zidovudine plus lamivudine plus didanosine in antiretroviral-naive HIV-1-infected Thai patients.
    Journal of acquired immune deficiency syndromes (1999), 2001, Jun-01, Volume: 27, Issue:2

    Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Didanosine; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Middle Aged; Reverse Transcriptase Inhibitors; RNA, Viral; Thailand; Treatment Outcome; Zidovudine

2001
High exposure to nevirapine in plasma is associated with an improved virological response in HIV-1-infected individuals.
    AIDS (London, England), 2001, Jun-15, Volume: 15, Issue:9

    Topics: Anti-HIV Agents; Didanosine; Double-Blind Method; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Nevirapine; Retrospective Studies; Reverse Transcriptase Inhibitors; RNA, Viral; Time Factors; Treatment Outcome; Zidovudine

2001
Development of drug resistance in patients receiving combinations of zidovudine, didanosine and nevirapine.
    AIDS (London, England), 2001, Jul-06, Volume: 15, Issue:10

    Topics: Anti-HIV Agents; Didanosine; Double-Blind Method; Drug Resistance, Microbial; Drug Therapy, Combination; Genotype; HIV Infections; HIV-1; Humans; Mutation; Nevirapine; Phenotype; Reverse Transcriptase Inhibitors; Zidovudine

2001
Comparison of genotypic and phenotypic resistance patterns of human immunodeficiency virus type 1 isolates from patients treated with stavudine and didanosine or zidovudine and lamivudine.
    The Journal of infectious diseases, 2001, Sep-15, Volume: 184, Issue:6

    Topics: Adult; Didanosine; Dideoxynucleosides; Drug Resistance, Microbial; Drug Therapy, Combination; Female; Follow-Up Studies; Genotype; HIV Infections; HIV-1; Humans; Lamivudine; Male; Microbial Sensitivity Tests; Phenotype; Point Mutation; Reverse Transcriptase Inhibitors; Stavudine; Zidovudine

2001
Potential adverse effects of structured therapeutic interruptions on the pool of HIV-infected cells.
    Journal of acquired immune deficiency syndromes (1999), 2001, Oct-01, Volume: 28, Issue:2

    Topics: Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Didanosine; Disease Progression; HIV Infections; HIV-1; Humans; Lamivudine; Lymphocyte Count; Morbidity; Prognosis; Ritonavir; RNA, Viral; Saquinavir; Viral Load; Zidovudine

2001
Evidence for prolonged clinical benefit from initial combination antiretroviral therapy: Delta extended follow-up.
    HIV medicine, 2001, Volume: 2, Issue:3

    Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Didanosine; Drug Therapy, Combination; Follow-Up Studies; HIV Infections; Humans; International Cooperation; Multicenter Studies as Topic; Randomized Controlled Trials as Topic; Reverse Transcriptase Inhibitors; Survival Analysis; Treatment Outcome; Zalcitabine; Zidovudine

2001
Evidence of immune reconstitution in antiretroviral drug-experienced patients with advanced HIV disease.
    AIDS research and human retroviruses, 2002, Jan-20, Volume: 18, Issue:2

    Topics: Adult; Aged; Alkynes; Anti-HIV Agents; Antigens, CD; Antiretroviral Therapy, Highly Active; Benzoxazines; Biomarkers; CD4 Lymphocyte Count; CD8-Positive T-Lymphocytes; Cyclopropanes; Didanosine; Dideoxynucleosides; Double-Blind Method; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Indinavir; Lamivudine; Male; Middle Aged; Oxazines; Reverse Transcriptase Inhibitors; RNA, Viral; Stavudine; Treatment Outcome; Viral Load; Zidovudine

2002
Impact of highly active antiretroviral therapy on cognitive processing in HIV infection: cross-sectional and longitudinal studies of event-related potentials.
    AIDS research and human retroviruses, 2002, May-01, Volume: 18, Issue:7

    Topics: Adult; AIDS Dementia Complex; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Cross-Sectional Studies; Didanosine; Drug Therapy, Combination; Evoked Potentials; Female; Humans; Longitudinal Studies; Male; Middle Aged; Prospective Studies; Treatment Outcome; Zalcitabine; Zidovudine

2002
L-carnitine reduces lymphocyte apoptosis and oxidant stress in HIV-1-infected subjects treated with zidovudine and didanosine.
    Antioxidants & redox signaling, 2002, Volume: 4, Issue:3

    Topics: Anti-HIV Agents; Apoptosis; Carnitine; Didanosine; Drug Therapy, Combination; fas Receptor; Flow Cytometry; HIV Infections; HIV-1; Humans; Hydrogen Peroxide; Male; Membrane Potentials; Mitochondria; Oxidants; Oxidative Stress; Phenotype; Reverse Transcriptase Inhibitors; Superoxides; T-Lymphocytes; Zidovudine

2002
Prognostic value of baseline human immunodeficiency virus type 1 DNA measurement for disease progression in patients receiving nucleoside therapy.
    The Journal of infectious diseases, 2003, Jan-01, Volume: 187, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Didanosine; Disease Progression; DNA, Viral; HIV-1; Humans; Multivariate Analysis; Prognosis; RNA, Viral; Zalcitabine; Zidovudine

2003
Predictive factors and selection of thymidine analogue mutations by nucleoside reverse transcriptase inhibitors according to initial regimen received.
    Antiviral therapy, 2003, Volume: 8, Issue:1

    Topics: Anti-HIV Agents; Didanosine; Dideoxynucleosides; Drug Resistance, Viral; Drug Therapy, Combination; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Mutation; Predictive Value of Tests; Reverse Transcriptase Inhibitors; Selection, Genetic; Thymidine; Zalcitabine; Zidovudine

2003
Hydroxyurea in combination with didanosine and stavudine in antiretroviral-experienced HIV-infected subjects with a review of the literature.
    International journal of STD & AIDS, 2003, Volume: 14, Issue:5

    Topics: Adult; Anti-HIV Agents; Antineoplastic Agents; Antiretroviral Therapy, Highly Active; Didanosine; Drug Administration Schedule; Drug Therapy, Combination; Female; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Hydroxyurea; Male; Middle Aged; Reverse Transcriptase Inhibitors; RNA, Viral; Stavudine; Viral Load; Zidovudine

2003
Feeding risk cut for HIV-infected women.
    Lancet (London, England), 2003, Jul-26, Volume: 362, Issue:9380

    Topics: Anti-HIV Agents; Breast Feeding; Didanosine; Female; HIV Infections; HIV-1; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Nevirapine; Pregnancy; Pregnancy Complications, Infectious; Risk Factors; Rwanda; Uganda; Zidovudine

2003
Nucleoside analogue mutations and Q151M in HIV-1 subtype A/E infection treated with nucleoside reverse transcriptase inhibitors.
    AIDS (London, England), 2003, Sep-05, Volume: 17, Issue:13

    Topics: Anti-HIV Agents; Didanosine; Drug Resistance, Multiple; Drug Resistance, Viral; Drug Therapy, Combination; Genotype; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Mutation; Reverse Transcriptase Inhibitors; Stavudine; Zidovudine

2003
Comparison of sequential three-drug regimens as initial therapy for HIV-1 infection.
    The New England journal of medicine, 2003, Dec-11, Volume: 349, Issue:24

    Topics: Adult; Alkynes; Anti-Retroviral Agents; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; Didanosine; Double-Blind Method; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Middle Aged; Nelfinavir; Oxazines; RNA, Viral; Stavudine; Time Factors; Treatment Failure; Zidovudine

2003
Comparison of four-drug regimens and pairs of sequential three-drug regimens as initial therapy for HIV-1 infection.
    The New England journal of medicine, 2003, Dec-11, Volume: 349, Issue:24

    Topics: Adult; Alkynes; Anti-Retroviral Agents; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; Didanosine; Double-Blind Method; Drug Resistance, Viral; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Mutation; Nelfinavir; Oxazines; Stavudine; Time Factors; Treatment Failure; Zidovudine

2003
Mutations linked to drug resistance, human immunodeficiency virus type 1 biologic phenotype and their association with disease progression in children receiving nucleoside reverse transcriptase inhibitors.
    The Pediatric infectious disease journal, 2004, Volume: 23, Issue:1

    Topics: Case-Control Studies; CD4 Lymphocyte Count; Child; Child, Preschool; Didanosine; Drug Resistance, Viral; Female; HIV Infections; HIV-1; Humans; Infant; Male; Mutation; Pharmacogenetics; Phenotype; Polymerase Chain Reaction; Probability; Prospective Studies; Reference Values; Reverse Transcriptase Inhibitors; RNA, Viral; Statistics, Nonparametric; Viral Load; Zidovudine

2004
Three-year durability of dual-nucleoside versus triple-nucleoside therapy in a Thai population with HIV infection.
    Journal of acquired immune deficiency syndromes (1999), 2004, Jun-01, Volume: 36, Issue:2

    Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Didanosine; Dideoxynucleosides; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Retrospective Studies; RNA, Viral; Stavudine; Thailand; Time Factors; Zidovudine

2004
High virological failure rate in HIV patients after switching to a regimen with two nucleoside reverse transcriptase inhibitors plus tenofovir.
    AIDS (London, England), 2005, Apr-29, Volume: 19, Issue:7

    Topics: Acquired Immunodeficiency Syndrome; Adenine; Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Didanosine; Drug Resistance, Multiple, Viral; Female; Follow-Up Studies; HIV-1; Humans; Male; Middle Aged; Multivariate Analysis; Organophosphonates; Reverse Transcriptase Inhibitors; RNA, Viral; Tenofovir; Treatment Failure; Viral Load; Zidovudine

2005
Pharmacokinetics of didanosine and drug resistance mutations in infants exposed to zidovudine during gestation or postnatally and treated with didanosine or zidovudine in the first three months of life.
    The Pediatric infectious disease journal, 2005, Volume: 24, Issue:6

    Topics: Anti-HIV Agents; Didanosine; Drug Resistance, Viral; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Infant; Infant, Newborn; Male; Mutation; Pregnancy; Pregnancy Complications, Infectious; Reverse Transcriptase Inhibitors; Zidovudine

2005
Results of the ALBI trial: a randomized comparison of stavudine/didanosine, zidovudine/lamivudine and alternating treatment in antiretroviral-naive patients.
    Antiviral therapy, 1999, Volume: 4 Suppl 3

    Topics: Anti-HIV Agents; Didanosine; Drug Administration Schedule; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Lamivudine; Reverse Transcriptase Inhibitors; RNA, Viral; Stavudine; Treatment Outcome; Viral Load; Zidovudine

1999
Brain mitochondrial injury in human immunodeficiency virus-seropositive (HIV+) individuals taking nucleoside reverse transcriptase inhibitors.
    Journal of neurovirology, 2005, Volume: 11, Issue:4

    Topics: Adult; Aspartic Acid; Brain; Cell Respiration; Didanosine; Female; HIV Infections; Humans; Lamivudine; Magnetic Resonance Spectroscopy; Male; Middle Aged; Mitochondria; Mitochondrial Diseases; Reverse Transcriptase Inhibitors; Stavudine; Treatment Outcome; Zidovudine

2005
A prospective study of hearing changes after beginning zidovudine or didanosine in HIV-1 treatment-naïve people.
    BMC infectious diseases, 2006, Feb-20, Volume: 6

    Topics: Adult; Aging; Anti-HIV Agents; Didanosine; Female; Hearing Loss; HIV Infections; Humans; Male; Middle Aged; Prospective Studies; Zidovudine

2006
[Clinical trial comparing efficacy and safety of four highly active antiretroviral therapy (HAART) in antiretroviral-naive treatment with advanced HIV infection].
    Revista clinica espanola, 2006, Volume: 206, Issue:2

    Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Didanosine; Disease Progression; Female; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Male; Middle Aged; Ritonavir; Stavudine; Zidovudine

2006
Antiviral activity of nucleoside analogues during short-course monotherapy or dual therapy: its role in preventing HIV infection in infants.
    Journal of acquired immune deficiency syndromes (1999), 2006, Volume: 42, Issue:2

    Topics: Acidosis, Lactic; Anti-HIV Agents; CD4 Lymphocyte Count; Didanosine; Drug Therapy, Combination; Fatty Liver; Female; HIV Infections; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Male; Mothers; Pregnancy; Pregnancy Complications, Infectious; Prospective Studies; RNA, Viral; South Africa; Stavudine; Viral Load; Zidovudine

2006
Therapeutic potential of chloroquine added to zidovudine plus didanosine for HIV-1 infected children.
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2006, Volume: 89, Issue:8

    Topics: Anti-HIV Agents; Antimalarials; Child; Child, Preschool; Chloroquine; Didanosine; Female; HIV Infections; HIV-1; Humans; Male; Zidovudine

2006
Changes in the peripheral blood mtDNA levels in naive patients treated by different nucleoside reverse transcriptase inhibitor combinations and their association with subsequent lipodystrophy.
    AIDS research and human retroviruses, 2007, Volume: 23, Issue:1

    Topics: Adult; Anti-HIV Agents; Didanosine; DNA, Mitochondrial; Drug Therapy, Combination; Female; Follow-Up Studies; HIV Infections; HIV-Associated Lipodystrophy Syndrome; Humans; Lamivudine; Leukocytes, Mononuclear; Logistic Models; Male; Reverse Transcriptase Inhibitors; Stavudine; Surveys and Questionnaires; Time Factors; Zidovudine

2007
Effects of potent antiretroviral therapy on free testosterone levels and fat-free mass in men in a prospective, randomized trial: A5005s, a substudy of AIDS Clinical Trials Group Study 384.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2007, Jul-01, Volume: 45, Issue:1

    Topics: Adult; Anti-HIV Agents; Anti-Retroviral Agents; Didanosine; Double-Blind Method; HIV Infections; Humans; Lamivudine; Longitudinal Studies; Male; Nelfinavir; Prospective Studies; Stavudine; Testosterone; Zidovudine

2007
More on the treatment-tropism relationship: the impact of prior antiretroviral treatment on HIV coreceptor tropism among subjects entering AIDS clinical trials group 175.
    The Journal of infectious diseases, 2007, Jul-15, Volume: 196, Issue:2

    Topics: Adult; Anti-Retroviral Agents; Didanosine; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Middle Aged; Receptors, CCR5; Receptors, CXCR4; Zalcitabine; Zidovudine

2007
Long-term body fat outcomes in antiretroviral-naive participants randomized to nelfinavir or efavirenz or both plus dual nucleosides. Dual X-ray absorptiometry results from A5005s, a substudy of Adult Clinical Trials Group 384.
    Journal of acquired immune deficiency syndromes (1999), 2007, Aug-15, Volume: 45, Issue:5

    Topics: Absorptiometry, Photon; Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Body Composition; Cyclopropanes; Didanosine; Drug Therapy, Combination; Female; HIV; HIV Infections; HIV Protease Inhibitors; HIV-Associated Lipodystrophy Syndrome; Humans; Lamivudine; Male; Middle Aged; Nelfinavir; Prospective Studies; Stavudine; Time Factors; Treatment Outcome; United States; Zidovudine

2007
The risk of developing peripheral neuropathy induced by nucleoside reverse transcriptase inhibitors decreases over time: evidence from the Delta trial.
    Antiviral therapy, 2008, Volume: 13, Issue:2

    Topics: Adult; Anti-HIV Agents; Didanosine; Double-Blind Method; Drug Therapy, Combination; Female; HIV Infections; Humans; Incidence; Male; Middle Aged; Peripheral Nervous System Diseases; Reverse Transcriptase Inhibitors; Risk Factors; Time Factors; Zalcitabine; Zidovudine

2008
Switch from zidovudine- to non-zidovudine-containing regimens is associated with modest haematological improvement and no obvious clinical benefit: a substudy of the ANRS 099 ALIZE trial.
    The Journal of antimicrobial chemotherapy, 2008, Volume: 62, Issue:5

    Topics: Adult; Alkynes; Anti-HIV Agents; Bacterial Infections; Benzoxazines; Blood Platelets; Cardiovascular Diseases; Cyclopropanes; Deoxycytidine; Didanosine; Emtricitabine; Female; Hemoglobins; HIV Infections; Humans; Leukocyte Count; Male; Middle Aged; Neutrophils; Pancytopenia; Platelet Count; Prevalence; Zidovudine

2008
Didanosine, lamivudine, and efavirenz versus zidovudine, lamivudine, and efavirenz for the initial treatment of HIV type 1 infection: final analysis (48 weeks) of a prospective, randomized, noninferiority clinical trial, GESIDA 3903.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2008, Oct-15, Volume: 47, Issue:8

    Topics: Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; Didanosine; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Middle Aged; Prospective Studies; RNA, Viral; Severity of Illness Index; Treatment Outcome; Viral Load; Zidovudine

2008
Response to zidovudine/didanosine-containing combination antiretroviral therapy among HIV-1 subtype C-infected adults in Botswana: two-year outcomes from a randomized clinical trial.
    Journal of acquired immune deficiency syndromes (1999), 2009, May-01, Volume: 51, Issue:1

    Topics: Adult; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Botswana; CD4 Lymphocyte Count; Didanosine; Drug Tolerance; Female; HIV Infections; HIV-1; Humans; Male; Patient Compliance; RNA, Viral; Survival Analysis; Time Factors; Viremia; Zidovudine

2009
The impact of once-nightly versus twice-daily dosing and baseline beliefs about HAART on adherence to efavirenz-based HAART over 48 weeks: the NOCTE study.
    Journal of acquired immune deficiency syndromes (1999), 2010, Volume: 53, Issue:3

    Topics: Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Culture; Cyclopropanes; Didanosine; Drug Combinations; Female; HIV Infections; Humans; Lamivudine; Male; Medication Adherence; Middle Aged; Surveys and Questionnaires; Zidovudine

2010
A randomized factorial trial comparing 4 treatment regimens in treatment-naive HIV-infected persons with AIDS and/or a CD4 cell count <200 cells/μL in South Africa.
    The Journal of infectious diseases, 2010, Nov-15, Volume: 202, Issue:10

    Topics: Acquired Immunodeficiency Syndrome; Adult; Alkynes; Anti-HIV Agents; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; Didanosine; Drug Therapy, Combination; Female; HIV; Humans; Lamivudine; Lopinavir; Male; Pyrimidinones; Ritonavir; RNA, Viral; South Africa; Stavudine; Treatment Outcome; Zidovudine

2010
Long-term effectiveness and safety of didanosine combined with lamivudine and efavirenz or nevirapine in antiretroviral-naive patients: a 9-year cohort study in Senegal.
    Tropical medicine & international health : TM & IH, 2011, Volume: 16, Issue:2

    Topics: Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; Didanosine; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Middle Aged; Nevirapine; Treatment Outcome; Viral Load; Zidovudine

2011
Pre-antiretroviral therapy serum selenium concentrations predict WHO stages 3, 4 or death but not virologic failure post-antiretroviral therapy.
    Nutrients, 2014, Nov-13, Volume: 6, Issue:11

    Topics: Adult; Alkynes; Anti-HIV Agents; Atazanavir Sulfate; Benzoxazines; Body Mass Index; C-Reactive Protein; CD4 Lymphocyte Count; Cyclopropanes; Deoxycytidine; Didanosine; Disease Progression; Emtricitabine; Female; HIV Infections; Humans; Lamivudine; Logistic Models; Male; Multivariate Analysis; Oligopeptides; Prospective Studies; Pyridines; Risk Factors; Selenium; World Health Organization; Zidovudine

2014
Prevalence, incidence and predictors of peripheral neuropathy in African adults with HIV infection within the DART trial.
    AIDS (London, England), 2014, Nov-13, Volume: 28, Issue:17

    Topics: Adolescent; Adult; Aged; Anti-Retroviral Agents; Antitubercular Agents; Didanosine; Female; HIV Infections; Humans; Incidence; Isoniazid; Male; Middle Aged; Peripheral Nervous System Diseases; Prevalence; Risk Factors; Stavudine; Uganda; Young Adult; Zidovudine; Zimbabwe

2014

Other Studies

648 other study(ies) available for zidovudine and didanosine

ArticleYear
Synthesis and evaluation of novel ether lipid nucleoside conjugates for anti-HIV-1 activity.
    Journal of medicinal chemistry, 1991, Volume: 34, Issue:4

    Topics: Antiviral Agents; Cell Line; Didanosine; Dideoxynucleotides; Ethers; HIV-1; Humans; Indicators and Reagents; Molecular Structure; Phospholipid Ethers; Structure-Activity Relationship; Virus Replication; Zidovudine

1991
Synthesis and anti-HIV-1 activity of 4,5,6,7-tetrahydro-5-methylimidazo[4,5,1-jk][1,4]benzodiazepin-2(1H)-on e (TIBO) derivatives. 2.
    Journal of medicinal chemistry, 1991, Volume: 34, Issue:11

    Topics: Antiviral Agents; Benzodiazepines; HIV-1; Imidazoles; Microbial Sensitivity Tests; Structure-Activity Relationship; Virus Replication

1991
Synthesis and anti-HIV-1 activity of 4,5,6,7-tetrahydro-5-methylimidazo[4,5,1-jk][1,4]benzodiazepin- 2(1H)-one (TIBO) derivatives.
    Journal of medicinal chemistry, 1991, Volume: 34, Issue:2

    Topics: Antiviral Agents; Benzodiazepinones; Chemical Phenomena; Chemistry; HIV; Structure-Activity Relationship; Virus Replication

1991
Escherichia coli mediated biosynthesis and in vitro anti-HIV activity of lipophilic 6-halo-2',3'-dideoxypurine nucleosides.
    Journal of medicinal chemistry, 1991, Volume: 34, Issue:5

    Topics: Adenosine Deaminase; Cells, Cultured; Chemical Phenomena; Chemistry; Dideoxynucleosides; Escherichia coli; HIV; Kinetics; Prodrugs; Structure-Activity Relationship

1991
Potential anti-AIDS drugs. Lipophilic, adenosine deaminase-activated prodrugs.
    Journal of medicinal chemistry, 1991, Volume: 34, Issue:5

    Topics: Adenosine Deaminase; Antiviral Agents; Cells, Cultured; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Dideoxynucleosides; HIV; Kinetics; Prodrugs; Structure-Activity Relationship

1991
HIV-1 reverse transcriptase inhibitor design using artificial neural networks.
    Journal of medicinal chemistry, 1994, Aug-05, Volume: 37, Issue:16

    Topics: Algorithms; Cell Line; Drug Design; HIV Reverse Transcriptase; HIV-1; Humans; Molecular Structure; Neural Networks, Computer; Pyrimidines; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; T-Lymphocytes; Zidovudine

1994
Synthesis and evaluation of the anti-HIV activity of aza and deaza analogues of isoddA and their phosphates as prodrugs.
    Journal of medicinal chemistry, 1994, Oct-14, Volume: 37, Issue:21

    Topics: Adenosine Triphosphate; Antiviral Agents; Aza Compounds; Dideoxyadenosine; Dideoxynucleotides; HIV Reverse Transcriptase; HIV-1; HIV-2; Molecular Structure; Phosphates; Recombinant Proteins; Reverse Transcriptase Inhibitors

1994
Lipophilic, acid-stable, adenosine deaminase-activated anti-HIV prodrugs for central nervous system delivery. 2. 6-Halo and 6-alkoxy prodrugs of 2'-beta-fluoro-2',3'-dideoxyinosine.
    Journal of medicinal chemistry, 1995, Mar-31, Volume: 38, Issue:7

    Topics: Adenosine Deaminase; Antiviral Agents; Cells, Cultured; Didanosine; HIV Infections; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Prodrugs; Solubility

1995
Synthesis of acyclo-C-nucleosides in the imidazo[1,2-a]pyridine and pyrimidine series as antiviral agents.
    Journal of medicinal chemistry, 1996, Jul-05, Volume: 39, Issue:14

    Topics: Animals; Antiviral Agents; Chlorocebus aethiops; HeLa Cells; Humans; Nucleosides; Pyridines; Pyrimidines; Structure-Activity Relationship; Tumor Cells, Cultured; Vero Cells

1996
Synthesis and anti-HIV-1 activity of a series of 1-alkoxy-5-alkyl-6-(arylthio)uracils.
    Journal of medicinal chemistry, 1997, Jul-18, Volume: 40, Issue:15

    Topics: Animals; Anti-HIV Agents; HIV Reverse Transcriptase; HIV-1; Liver; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Rats; Rats, Sprague-Dawley; Spectrophotometry, Infrared; Structure-Activity Relationship; Uracil

1997
Rat multispecific organic anion transporter 1 (rOAT1) transports zidovudine, acyclovir, and other antiviral nucleoside analogs.
    The Journal of pharmacology and experimental therapeutics, 2000, Volume: 294, Issue:3

    Topics: Acyclovir; Animals; Anion Transport Proteins; Antiviral Agents; Carrier Proteins; Didanosine; In Vitro Techniques; Lamivudine; Oocytes; Rats; Stavudine; Transfection; Trifluridine; Xenopus laevis; Zalcitabine; Zidovudine

2000
New saponins from the starfish Certonardoa semiregularis.
    Journal of natural products, 2002, Volume: 65, Issue:11

    Topics: Animals; Antineoplastic Agents; Antiviral Agents; Artemia; HeLa Cells; Humans; Korea; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Saponins; Starfish; Stereoisomerism; Steroids

2002
Isolation of salicin derivatives from Homalium cochinchinensis and their antiviral activities.
    Journal of natural products, 2004, Volume: 67, Issue:4

    Topics: Anti-HIV Agents; Antiviral Agents; Benzyl Alcohols; Glucosides; Medicine, Traditional; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Plant Bark; Plant Leaves; Plant Roots; Plants, Medicinal; Salicaceae

2004
Extrapolation of human pharmacokinetic parameters from rat, dog, and monkey data: Molecular properties associated with extrapolative success or failure.
    Journal of pharmaceutical sciences, 2005, Volume: 94, Issue:7

    Topics: Algorithms; Animals; Dogs; Haplorhini; Humans; Pharmaceutical Preparations; Pharmacokinetics; Rats; Species Specificity; Tissue Distribution

2005
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Absence of a universal mechanism of mitochondrial toxicity by nucleoside analogs.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:7

    Topics: Animals; Antimetabolites; Carcinoma, Hepatocellular; Cell Line; Cell Line, Tumor; Cell Proliferation; Cell Survival; Didanosine; DNA, Mitochondrial; Dose-Response Relationship, Drug; Humans; Lactates; Liver Neoplasms; Mitochondria; Myocytes, Cardiac; Rats; Superoxides; Zalcitabine; Zidovudine

2007
Novel drug resistance pattern associated with the mutations K70G and M184V in human immunodeficiency virus type 1 reverse transcriptase.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:12

    Topics: Adenine; Amino Acid Substitution; Deoxycytidine; Didanosine; Dideoxynucleosides; Drug Resistance, Multiple, Viral; Emtricitabine; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Molecular Sequence Data; Mutation; Organophosphonates; Reverse Transcriptase Inhibitors; Stavudine; Tenofovir; Zidovudine

2007
Human immunodeficiency virus types 1 and 2 exhibit comparable sensitivities to Zidovudine and other nucleoside analog inhibitors in vitro.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:1

    Topics: Anti-HIV Agents; HeLa Cells; HIV-1; HIV-2; Humans; Microbial Sensitivity Tests; Reverse Transcriptase Inhibitors; Zidovudine

2008
Anti-BK virus activity of nucleoside analogs.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:4

    Topics: Adenine; BK Virus; Esters; Fatty Acids; Humans; Microbial Sensitivity Tests; Nucleosides; Organophosphonates; Virus Replication

2008
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Impact of nucleoside reverse transcriptase inhibitors on mitochondrial DNA and RNA in human skeletal muscle cells.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:8

    Topics: Cell Proliferation; Cells, Cultured; Dideoxynucleosides; DNA, Mitochondrial; Humans; Lamivudine; Muscle Fibers, Skeletal; Muscle, Skeletal; Myoblasts; Nucleosides; Reverse Transcriptase Inhibitors; Reverse Transcriptase Polymerase Chain Reaction; RNA; RNA, Mitochondrial; Stavudine; Zidovudine

2008
Unified QSAR approach to antimicrobials. 4. Multi-target QSAR modeling and comparative multi-distance study of the giant components of antiviral drug-drug complex networks.
    Bioorganic & medicinal chemistry, 2009, Jan-15, Volume: 17, Issue:2

    Topics: Anti-Infective Agents; Antiviral Agents; Artificial Intelligence; Computer Simulation; Drug Evaluation, Preclinical; Molecular Structure; Quantitative Structure-Activity Relationship

2009
Human immunodeficiency virus type 1 isolates with the reverse transcriptase (RT) mutation Q145M retain nucleoside and nonnucleoside RT inhibitor susceptibility.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:5

    Topics: Amino Acid Sequence; Anti-HIV Agents; Drug Resistance, Viral; Genotype; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Microbial Sensitivity Tests; Molecular Sequence Data; Mutation; Nucleosides; Phenotype; Reverse Transcriptase Inhibitors

2009
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Anti-human immunodeficiency virus activity, cross-resistance, cytotoxicity, and intracellular pharmacology of the 3'-azido-2',3'-dideoxypurine nucleosides.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:9

    Topics: Anti-HIV Agents; Cell Line, Tumor; Cell Survival; Cells, Cultured; Dideoxynucleosides; HIV Infections; HIV-1; Humans; Molecular Structure; Reverse Transcriptase Inhibitors

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of hexadecyloxypropyl tenofovir (CMX157) for treatment of infection caused by wild-type and nucleoside/nucleotide-resistant HIV.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:7

    Topics: Adenine; Anti-HIV Agents; Cell Survival; Cells, Cultured; Drug Resistance, Viral; HIV Infections; HIV-1; Humans; Macrophages; Nucleosides; Nucleotides; Organophosphonates; Tenofovir

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
Anti-HIV and antiplasmodial activity of original flavonoid derivatives.
    Bioorganic & medicinal chemistry, 2010, Aug-15, Volume: 18, Issue:16

    Topics: Anti-HIV Agents; Antimalarials; Cell Line; Cell Survival; Flavonoids; HIV; HIV Infections; Humans; Malaria, Falciparum; Plasmodium falciparum

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Arylazolylthioacetanilide. Part 8: Design, synthesis and biological evaluation of novel 2-(2-(2,4-dichlorophenyl)-2H-1,2,4-triazol-3-ylthio)-N-arylacetamides as potent HIV-1 inhibitors.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:10

    Topics: Acetamides; Anti-HIV Agents; Cell Line; HIV Infections; HIV Reverse Transcriptase; HIV-1; HIV-2; Humans; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Triazoles; Virus Replication

2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Towards new C6-rigid S-DABO HIV-1 reverse transcriptase inhibitors: synthesis, biological investigation and molecular modeling studies.
    Bioorganic & medicinal chemistry, 2013, Nov-01, Volume: 21, Issue:21

    Topics: Binding Sites; HIV Reverse Transcriptase; HIV-1; Humans; Molecular Docking Simulation; Protein Binding; Protein Structure, Tertiary; Pyrimidines; Pyrimidinones; Reverse Transcriptase Inhibitors; Structure-Activity Relationship

2013
Design, synthesis and preliminary SAR studies of novel N-arylmethyl substituted piperidine-linked aniline derivatives as potent HIV-1 NNRTIs.
    Bioorganic & medicinal chemistry, 2014, Jan-01, Volume: 22, Issue:1

    Topics: Aniline Compounds; Anti-HIV Agents; Drug Design; HIV-1; Humans; Models, Molecular; Piperidines; Structure-Activity Relationship

2014
Jatrophane diterpenes as inhibitors of chikungunya virus replication: structure-activity relationship and discovery of a potent lead.
    Journal of natural products, 2014, Jun-27, Volume: 77, Issue:6

    Topics: Alphavirus Infections; Antiviral Agents; Chikungunya Fever; Chikungunya virus; Diterpenes; Euphorbia; France; HIV-1; HIV-2; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Semliki forest virus; Sindbis Virus; Structure-Activity Relationship; Virus Replication

2014
Design, synthesis and anti-HIV evaluation of novel diarylnicotinamide derivatives (DANAs) targeting the entrance channel of the NNRTI binding pocket through structure-guided molecular hybridization.
    European journal of medicinal chemistry, 2014, Nov-24, Volume: 87

    Topics: Anti-HIV Agents; Catalytic Domain; Dose-Response Relationship, Drug; Drug Design; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Models, Molecular; Molecular Structure; Niacinamide; Protein Conformation; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Tumor Cells, Cultured

2014
Synthesis and biological evaluation of DAPY-DPEs hybrids as non-nucleoside inhibitors of HIV-1 reverse transcriptase.
    Bioorganic & medicinal chemistry, 2015, Feb-01, Volume: 23, Issue:3

    Topics: Anti-HIV Agents; Binding Sites; Cell Line; Drug Design; HIV Reverse Transcriptase; HIV-1; Humans; Pyrimidines; Reverse Transcriptase Inhibitors; Structure-Activity Relationship

2015
Fused heterocycles bearing bridgehead nitrogen as potent HIV-1 NNRTIs. Part 3: optimization of [1,2,4]triazolo[1,5-a]pyrimidine core via structure-based and physicochemical property-driven approaches.
    European journal of medicinal chemistry, 2015, Mar-06, Volume: 92

    Topics: Anti-HIV Agents; Cell Line, Tumor; Dose-Response Relationship, Drug; Heterocyclic Compounds; Heterocyclic Compounds, 2-Ring; HIV Reverse Transcriptase; HIV-1; Humans; Microbial Sensitivity Tests; Models, Molecular; Molecular Structure; Nitrogen; Reverse Transcriptase Inhibitors; Solubility; Structure-Activity Relationship; Sulfones

2015
Design, synthesis of new β-carboline derivatives and their selective anti-HIV-2 activity.
    Bioorganic & medicinal chemistry letters, 2015, Mar-15, Volume: 25, Issue:6

    Topics: Carbolines; Drug Design; HIV Reverse Transcriptase; HIV-1; HIV-2; Humans; Piperazines; Reverse Transcriptase Inhibitors; Structure-Activity Relationship

2015
Fused heterocycles bearing bridgehead nitrogen as potent HIV-1 NNRTIs. Part 4: design, synthesis and biological evaluation of novel imidazo[1,2-a]pyrazines.
    European journal of medicinal chemistry, 2015, Mar-26, Volume: 93

    Topics: Anti-HIV Agents; Chemistry Techniques, Synthetic; Computational Biology; Drug Design; HIV Reverse Transcriptase; HIV-1; Imidazoles; Molecular Docking Simulation; Protein Conformation; Pyrazines; Reverse Transcriptase Inhibitors; Structure-Activity Relationship

2015
Antiviral Activity of Flexibilane and Tigliane Diterpenoids from Stillingia lineata.
    Journal of natural products, 2015, May-22, Volume: 78, Issue:5

    Topics: Antiviral Agents; Chikungunya virus; Diterpenes; Euphorbiaceae; France; HCT116 Cells; HIV-1; HIV-2; Humans; Macrocyclic Compounds; MCF-7 Cells; Molecular Structure; Semliki forest virus; Sindbis Virus; Virus Replication

2015
Ionic derivatives of betulinic acid exhibit antiviral activity against herpes simplex virus type-2 (HSV-2), but not HIV-1 reverse transcriptase.
    Bioorganic & medicinal chemistry letters, 2015, Aug-15, Volume: 25, Issue:16

    Topics: Acyclovir; Animals; Antiviral Agents; Betulinic Acid; Chlorocebus aethiops; Herpesvirus 2, Human; HIV Reverse Transcriptase; HIV-1; Humans; Pentacyclic Triterpenes; Triterpenes; Vero Cells; Virus Replication

2015
Design, synthesis and evaluation of novel HIV-1 NNRTIs with dual structural conformations targeting the entrance channel of the NNRTI binding pocket.
    European journal of medicinal chemistry, 2016, Jun-10, Volume: 115

    Topics: Anti-HIV Agents; Binding Sites; Dose-Response Relationship, Drug; Drug Design; HIV Reverse Transcriptase; HIV-1; Humans; Microbial Sensitivity Tests; Molecular Structure; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Virus Replication

2016
Design, synthesis and anti-HIV activity of novel quinoxaline derivatives.
    European journal of medicinal chemistry, 2016, Jul-19, Volume: 117

    Topics: Animals; Anti-HIV Agents; Chlorocebus aethiops; Computer Simulation; Drug Design; HIV Integrase; Molecular Docking Simulation; Quantitative Structure-Activity Relationship; Quinoxalines; Vero Cells

2016
1,6-Bis[(benzyloxy)methyl]uracil derivatives-Novel antivirals with activity against HIV-1 and influenza H1N1 virus.
    Bioorganic & medicinal chemistry, 2016, 06-01, Volume: 24, Issue:11

    Topics: Animals; Antiviral Agents; Cells, Cultured; Dogs; Dose-Response Relationship, Drug; HIV-1; Influenza A Virus, H1N1 Subtype; Madin Darby Canine Kidney Cells; Microbial Sensitivity Tests; Models, Molecular; Molecular Structure; Structure-Activity Relationship; Uracil

2016
Synthesis and antiproliferative evaluation of novel 2-(4H-1,2,4-triazole-3-ylthio)acetamide derivatives as inducers of apoptosis in cancer cells.
    European journal of medicinal chemistry, 2016, Oct-04, Volume: 121

    Topics: Acetamides; Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Humans; Membrane Potential, Mitochondrial; Structure-Activity Relationship; Triazoles

2016
Systematic evaluation of methyl ester bioisosteres in the context of developing alkenyldiarylmethanes (ADAMs) as non-nucleoside reverse transcriptase inhibitors (NNRTIs) for anti-HIV-1 chemotherapy.
    Bioorganic & medicinal chemistry, 2016, 07-01, Volume: 24, Issue:13

    Topics: Anti-HIV Agents; Drug Stability; Esters; HIV-1; Humans; Inhibitory Concentration 50; Methane; Models, Molecular; Reverse Transcriptase Inhibitors

2016
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
    Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16

    Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone

2016
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
Novel mutation in the human immunodeficiency virus type 1 reverse transcriptase gene that encodes cross-resistance to 2',3'-dideoxyinosine and 2',3'-dideoxycytidine.
    Journal of virology, 1992, Volume: 66, Issue:12

    Topics: Acquired Immunodeficiency Syndrome; Base Sequence; Cell Line; Cloning, Molecular; Didanosine; Drug Resistance, Microbial; Genetic Variation; HIV Reverse Transcriptase; HIV-1; Humans; Molecular Sequence Data; Mutation; Oligodeoxyribonucleotides; Polymerase Chain Reaction; Restriction Mapping; RNA-Directed DNA Polymerase; Zalcitabine; Zidovudine

1992
Response of Ethiopian human immunodeficiency virus type 1 isolates to antiviral compounds.
    Antiviral research, 1992, Oct-01, Volume: 19, Issue:4

    Topics: Acquired Immunodeficiency Syndrome; Didanosine; Ethiopia; HIV Core Protein p24; HIV-1; Humans; Interferon-alpha; Microbial Sensitivity Tests; Mutation; RNA-Directed DNA Polymerase; Sweden; Zidovudine

1992
Combination therapy for HIV infection: getting closer.
    Annals of internal medicine, 1992, Jan-01, Volume: 116, Issue:1

    Topics: Didanosine; Drug Therapy, Combination; HIV Infections; Humans; Zalcitabine; Zidovudine

1992
Trial of three drugs for HIV-infected patients.
    American family physician, 1992, Volume: 45, Issue:4

    Topics: Clinical Trials as Topic; Didanosine; HIV Infections; Humans; Zalcitabine; Zidovudine

1992
Sodium-dependent nucleoside transport in choroid plexus from rabbit. Evidence for a single transporter for purine and pyrimidine nucleosides.
    The Journal of biological chemistry, 1992, May-05, Volume: 267, Issue:13

    Topics: Adenosine Triphosphate; Animals; Carrier Proteins; Choroid Plexus; Cytarabine; Didanosine; Membrane Proteins; Nucleoside Transport Proteins; Purine Nucleosides; Pyrimidine Nucleosides; Rabbits; Sodium; Substrate Specificity; Zalcitabine; Zidovudine

1992
Different pattern of activity of inhibitors of the human immunodeficiency virus in lymphocytes and monocyte/macrophages.
    Antiviral research, 1992, Volume: 17, Issue:4

    Topics: Adenine; Antibodies, Viral; Antiviral Agents; Benzodiazepines; CD4 Antigens; Cytokines; Didanosine; Doxorubicin; Drug Interactions; HIV; HIV Infections; Humans; Imidazoles; Leukocytes, Mononuclear; Lymphocytes; Macrophages; Monocytes; Organ Specificity; Organophosphonates; Zalcitabine; Zidovudine

1992
Treatment of HIV infection: the antiretroviral nucleoside analogues. Introduction.
    Hospital practice (Office ed.), 1992, Volume: 27 Suppl 2

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Didanosine; Drug Evaluation; HIV Infections; HIV-1; Humans; Nucleosides; Zalcitabine; Zidovudine

1992
Inhibition of HIV infection of resting peripheral blood lymphocytes by nucleosides.
    AIDS research and human retroviruses, 1992, Volume: 8, Issue:7

    Topics: Base Sequence; Cells, Cultured; Didanosine; DNA, Viral; HIV; Humans; Lymphocyte Activation; Molecular Sequence Data; Polymerase Chain Reaction; Proviruses; T-Lymphocytes; Virus Replication; Zalcitabine; Zidovudine

1992
Antiviral nucleoside toxicity in canine bone marrow progenitor cells and its relationship to drug permeation.
    European journal of haematology, 1992, Volume: 49, Issue:2

    Topics: Animals; Biological Transport, Active; Colony-Forming Units Assay; Didanosine; Dipyridamole; Dogs; Dose-Response Relationship, Drug; Erythrocytes; Female; Granulocytes; Hematopoietic Stem Cells; In Vitro Techniques; Macrophages; Zalcitabine; Zidovudine

1992
Anti-human immunodeficiency virus (HIV) agents are also potent and selective inhibitors of feline immunodeficiency virus (FIV)-induced cytopathic effect: development of a new method for screening of anti-FIV substances in vitro.
    Antiviral research, 1992, Volume: 19, Issue:2

    Topics: Animals; Anthracyclines; Antibiotics, Antineoplastic; Antiviral Agents; Cats; Cell Fusion; Cells, Cultured; Cytopathogenic Effect, Viral; Dextran Sulfate; Didanosine; Drug Evaluation, Preclinical; Heparin; HIV; Humans; Immunodeficiency Virus, Feline; Virus Replication; Zidovudine

1992
The transfer of anti-human immunodeficiency virus nucleoside compounds by the term human placenta.
    American journal of obstetrics and gynecology, 1992, Volume: 167, Issue:6

    Topics: Antiviral Agents; Chromatography, High Pressure Liquid; Didanosine; Female; HIV Infections; Humans; Maternal-Fetal Exchange; Osmolar Concentration; Placenta; Pregnancy; Zalcitabine; Zidovudine

1992
Effect of six virustatic nucleoside analogues on the development of fetal rat thymus in organ culture.
    Archives of toxicology, 1992, Volume: 66, Issue:10

    Topics: Animals; Antiviral Agents; Cell Differentiation; Cell Division; Cells, Cultured; Didanosine; Female; Flow Cytometry; Ganciclovir; Immunity, Cellular; Male; Nucleotides; Organ Culture Techniques; Pregnancy; Rats; Rats, Wistar; Thymus Gland; Vidarabine; Zalcitabine; Zidovudine

1992
Criteria for use of didanosine in adult and pediatric patients.
    Clinical pharmacy, 1992, Volume: 11, Issue:10

    Topics: Adult; Child, Preschool; Didanosine; HIV Infections; Humans; Infant; Leukocyte Count; Zidovudine

1992
Testing an anti-HIV trio.
    Lancet (London, England), 1992, Mar-14, Volume: 339, Issue:8794

    Topics: Clinical Trials as Topic; Didanosine; Drug Therapy, Combination; HIV Infections; Humans; Zalcitabine; Zidovudine

1992
Didanosine therapy in patients intolerant of or failing zidovudine therapy.
    The Annals of pharmacotherapy, 1992, Volume: 26, Issue:11

    Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Complex; CD4-Positive T-Lymphocytes; Didanosine; Female; HIV Core Protein p24; Humans; Leukocyte Count; Male; Peripheral Nervous System Diseases; Retrospective Studies; Time Factors; Treatment Failure; Zidovudine

1992
[HIV-1 proviral DNA sequences in the saliva of patients with HIV infection].
    Bollettino della Societa italiana di biologia sperimentale, 1992, Volume: 68, Issue:7

    Topics: Base Sequence; CD4-Positive T-Lymphocytes; Didanosine; DNA, Viral; Genes, env; HIV Infections; HIV-1; Humans; Leukocyte Count; Molecular Sequence Data; Polymerase Chain Reaction; Proviruses; Saliva; Zidovudine

1992
[AIDS. 3rd European conference on the clinical aspects and treatment of HIV infection. Paris, 12-13 March 1992. 4th German AIDS congress. Wiesbaden, 25-28 March 1992. 8th International AIDS Conference. Amsterdam, 19-24 July 1992].
    Der Internist, 1992, Volume: 33, Issue:10 Suppl [

    Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Opportunistic Infections; Didanosine; Drug Therapy, Combination; HIV Infections; Humans; Zidovudine

1992
Effects of bone marrow stimulatory cytokines on human immunodeficiency virus replication and the antiviral activity of dideoxynucleosides in cultures of monocyte/macrophages.
    Blood, 1992, Aug-15, Volume: 80, Issue:4

    Topics: Antiviral Agents; Bone Marrow; Cells, Cultured; Cytokines; Didanosine; Dideoxynucleosides; Erythropoietin; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Stimulating Factor; HIV; Humans; Macrophage Colony-Stimulating Factor; Macrophages; Monocytes; Virus Replication; Zalcitabine; Zidovudine

1992
(-)-2'-deoxy-3'-thiacytidine is a potent, highly selective inhibitor of human immunodeficiency virus type 1 and type 2 replication in vitro.
    Antimicrobial agents and chemotherapy, 1992, Volume: 36, Issue:4

    Topics: Cell Death; Cells, Cultured; Didanosine; Giant Cells; HIV Reverse Transcriptase; HIV-1; HIV-2; Humans; Lamivudine; RNA-Directed DNA Polymerase; Tritium; Virus Replication; Zalcitabine; Zidovudine

1992
Children with AIDS benefit from two-drug regimen.
    Oncology (Williston Park, N.Y.), 1992, Volume: 6, Issue:7

    Topics: Acquired Immunodeficiency Syndrome; Adolescent; Child; Child, Preschool; Didanosine; Drug Synergism; Drug Therapy, Combination; Humans; Zidovudine

1992
Zidovudine-induced blockade of the expression and function of the erythropoietin receptor.
    Biochemical pharmacology, 1992, Sep-25, Volume: 44, Issue:6

    Topics: Animals; Cell Differentiation; Colony-Forming Units Assay; Didanosine; Dose-Response Relationship, Drug; Down-Regulation; Hematopoietic Stem Cells; Male; Mice; Receptors, Erythropoietin; RNA, Messenger; Signal Transduction; Zidovudine

1992
Starting therapy for an HIV-infected patient.
    The Journal of the American Osteopathic Association, 1992, Volume: 92, Issue:9

    Topics: Didanosine; HIV Infections; Humans; Zidovudine

1992
Continued zidovudine or didanosine for human immunodeficiency virus infection.
    The New England journal of medicine, 1992, Nov-26, Volume: 327, Issue:22

    Topics: Didanosine; HIV Infections; Humans; Zidovudine

1992
Cerebral artery aneurysms in children infected with human immunodeficiency virus.
    The Journal of pediatrics, 1992, Volume: 121, Issue:6

    Topics: Brain; Cerebral Angiography; Child; Didanosine; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Intracranial Aneurysm; Magnetic Resonance Imaging; Male; Zidovudine

1992
Approval for broader use of DDI.
    American family physician, 1992, Volume: 46, Issue:6

    Topics: Didanosine; Drug Approval; HIV Infections; HIV-1; Humans; United States; United States Food and Drug Administration; Zidovudine

1992
DDI more effective than AZT.
    Minnesota medicine, 1992, Volume: 75, Issue:6

    Topics: Didanosine; HIV Infections; Zidovudine

1992
Treatment of patients with advanced HIV infection and zidovudine intolerance with dideoxyinosine.
    AIDS (London, England), 1992, Volume: 6, Issue:7

    Topics: Adult; Didanosine; Drug Tolerance; HIV Infections; Humans; Male; Middle Aged; Zidovudine

1992
An improved method for monitoring efficacy of anti-retroviral therapy in HIV-infected individuals: a highly sensitive HIV p24 antigen assay.
    Journal of clinical laboratory analysis, 1992, Volume: 6, Issue:3

    Topics: Biomarkers; Didanosine; Enzyme-Linked Immunosorbent Assay; Evaluation Studies as Topic; HIV Core Protein p24; HIV Infections; Humans; Sensitivity and Specificity; Zidovudine

1992
[AIDS from the CIA?].
    Medizinische Monatsschrift fur Pharmazeuten, 1992, Volume: 15, Issue:8

    Topics: Didanosine; Government Agencies; HIV Infections; HIV-1; HIV-2; Humans; Mass Media; Zidovudine

1992
Ganciclovir antagonizes the anti-human immunodeficiency virus type 1 activity of zidovudine and didanosine in vitro.
    Antimicrobial agents and chemotherapy, 1992, Volume: 36, Issue:5

    Topics: Didanosine; Drug Interactions; Ganciclovir; HIV-1; Zidovudine

1992
Didanosine and zidovudine resistance patterns in clinical isolates of human immunodeficiency virus type 1 as determined by a replication endpoint concentration assay.
    Antimicrobial agents and chemotherapy, 1992, Volume: 36, Issue:5

    Topics: Didanosine; Drug Resistance, Microbial; HIV-1; Humans; In Vitro Techniques; Methods; Virus Replication; Zidovudine

1992
In vitro inhibition of human immunodeficiency virus (HIV) type 1 replication by C2 symmetry-based HIV protease inhibitors as single agents or in combinations.
    Antimicrobial agents and chemotherapy, 1992, Volume: 36, Issue:5

    Topics: Didanosine; Drug Interactions; Drug Therapy, Combination; HIV Protease Inhibitors; HIV-1; Humans; Virus Replication; Zidovudine

1992
The effects of AZT and DDI on pre- and postimplantation mammalian embryos: an in vivo and in vitro study.
    AIDS research and human retroviruses, 1992, Volume: 8, Issue:5

    Topics: Animals; Blastocyst; Cells, Cultured; Didanosine; Electrophoresis, Polyacrylamide Gel; Embryonic and Fetal Development; Embryonic Development; Female; Fluorescent Antibody Technique; Humans; Kinetics; Mice; Microscopy, Electron, Scanning; Pregnancy; Zidovudine

1992
Loss of synergistic response to combinations containing AZT in AZT-resistant HIV-1.
    AIDS research and human retroviruses, 1992, Volume: 8, Issue:7

    Topics: Antiviral Agents; Cells, Cultured; Didanosine; Drug Resistance, Microbial; Drug Synergism; HIV-1; Humans; Thymidine; Zidovudine

1992
Pharmacokinetic evaluation of drug interactions with anti-HIV drugs, II: Effect of 2',3'-dideoxyinosine (ddI) on zidovudine kinetics in monkeys.
    AIDS research and human retroviruses, 1992, Volume: 8, Issue:2

    Topics: Animals; Data Interpretation, Statistical; Didanosine; Drug Interactions; Macaca fascicularis; Male; Zidovudine

1992
The effect of combinations of ampligen and zidovudine or dideoxyinosine against human immunodeficiency viruses in vitro.
    Antiviral research, 1992, Volume: 17, Issue:2

    Topics: Antiviral Agents; Cell Line; Cytopathogenic Effect, Viral; Didanosine; Drug Synergism; HeLa Cells; HIV; Humans; Poly I-C; Poly U; Zidovudine

1992
Thrombocytopenia in children infected with human immunodeficiency virus: long-term follow-up and therapeutic considerations.
    Journal of acquired immune deficiency syndromes, 1992, Volume: 5, Issue:5

    Topics: Acquired Immunodeficiency Syndrome; Child; Child, Preschool; Didanosine; Follow-Up Studies; Humans; Immunoglobulins, Intravenous; Infant; Infant, Newborn; New York; Platelet Count; Thrombocytopenia; Zidovudine

1992
Mycobacterium haemophilum osteomyelitis in an AIDS patient.
    New Jersey medicine : the journal of the Medical Society of New Jersey, 1992, Volume: 89, Issue:3

    Topics: Acquired Immunodeficiency Syndrome; Adult; Diagnosis, Differential; Didanosine; Drug Therapy, Combination; Female; Humans; Minocycline; Mycobacterium Infections, Nontuberculous; Opportunistic Infections; Osteomyelitis; Tuberculosis, Osteoarticular; Zidovudine

1992
Intestinal permeability in HIV infection: proper controls are necessary.
    The American journal of gastroenterology, 1992, Volume: 87, Issue:5

    Topics: California; Congresses as Topic; Didanosine; HIV Infections; Humans; Intestinal Absorption; Research Design; Zidovudine

1992
Generation of nucleoside-resistant variants of HIV-1 by in vitro selection in the presence of AZT or DDI but no by combinations.
    Leukemia, 1992, Volume: 6 Suppl 3

    Topics: Amino Acid Sequence; Didanosine; Drug Combinations; Drug Resistance, Microbial; HIV-1; Humans; Interferon alpha-2; Interferon-alpha; Molecular Sequence Data; Mutation; Polymerase Chain Reaction; Recombinant Proteins; Zidovudine

1992
Survival for women and men with AIDS.
    The Journal of infectious diseases, 1992, Volume: 166, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Adult; Age Factors; Didanosine; Female; Humans; Longevity; Male; Middle Aged; Proportional Hazards Models; Prospective Studies; Risk Factors; San Francisco; Sex Characteristics; Zidovudine

1992
Lack of pharmacokinetic interaction between intravenous 2',3'-dideoxyinosine and 3'-azido-3'-deoxythymidine in rats.
    Antimicrobial agents and chemotherapy, 1992, Volume: 36, Issue:3

    Topics: Animals; Didanosine; Drug Interactions; Half-Life; Injections, Intravenous; Metabolic Clearance Rate; Rats; Zidovudine

1992
The PC12 cell as a model for studies of the mechanism of induction of peripheral neuropathy by anti-HIV-1 dideoxynucleoside analogs.
    Biochemical pharmacology, 1991, Jun-21, Volume: 42, Issue:1

    Topics: Animals; Axons; Bone Marrow; Cell Division; Cell Line, Transformed; Didanosine; Dideoxynucleosides; Dose-Response Relationship, Drug; Peripheral Nervous System Diseases; Stavudine; Tumor Cells, Cultured; Zalcitabine; Zidovudine

1991
Therapeutic options expand, take new directions.
    JAMA, 1991, Aug-14, Volume: 266, Issue:6

    Topics: Acquired Immunodeficiency Syndrome; Didanosine; Humans; United States; Zalcitabine; Zidovudine

1991
Bacterial infections in human immunodeficiency virus type 1-infected children: the impact of central venous catheters and antiretroviral agents.
    The Pediatric infectious disease journal, 1991, Volume: 10, Issue:11

    Topics: Adolescent; Antiviral Agents; Bacterial Infections; Catheterization, Central Venous; Child; Child, Preschool; Didanosine; Female; HIV Infections; HIV-1; Humans; Male; Retrospective Studies; Zalcitabine; Zidovudine

1991
Modified tetrazolium-based colorimetric method for determining the activities of anti-HIV compounds.
    Journal of virological methods, 1991, Volume: 33, Issue:3

    Topics: Antiviral Agents; Cell Line; Colorimetry; Didanosine; Foscarnet; HIV-1; Humans; Phosphonoacetic Acid; Tetrazolium Salts; Thymidine; Zalcitabine; Zidovudine

1991
Experimental studies of the hematologic and immune system toxicity of nucleoside derivatives used against HIV infection.
    International journal of immunopharmacology, 1991, Volume: 13 Suppl 1

    Topics: Animals; Bone Marrow; Didanosine; Dideoxyadenosine; Female; HIV Infections; Immune System; Immunoglobulin M; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Zalcitabine; Zidovudine

1991
AIDS patients' concerns at centre stage during Vancouver conference.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 1991, Jul-15, Volume: 145, Issue:2

    Topics: Acquired Immunodeficiency Syndrome; Canada; Clinical Trials as Topic; Didanosine; Humans; Patient Participation; Risk Factors; Zidovudine

1991
The selective toxicity of medications used in the treatment of AIDS on the CEM human leukemic CD4+ T-cell line.
    Drug and chemical toxicology, 1991, Volume: 14, Issue:3

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; CD4-Positive T-Lymphocytes; Didanosine; Humans; Leukemia; Tumor Cells, Cultured; Zidovudine

1991
Pharmacokinetics of anti-HIV nucleosides in microswine.
    The Journal of pharmacy and pharmacology, 1991, Volume: 43, Issue:12

    Topics: Animals; Antiviral Agents; Chromatography, High Pressure Liquid; Didanosine; Half-Life; HIV; Male; Nucleosides; Swine; Swine, Miniature; Zalcitabine; Zidovudine

1991
Potent and selective inhibition of HIV-1 replication in vitro by a novel series of TIBO derivatives.
    Nature, 1990, Feb-01, Volume: 343, Issue:6257

    Topics: Animals; Antiviral Agents; Benzodiazepines; CD4-Positive T-Lymphocytes; Cell Line; Cytopathogenic Effect, Viral; Didanosine; Dogs; HIV-1; HIV-2; Humans; Imidazoles; Lymphocytes; Molecular Conformation; Molecular Structure; Reverse Transcriptase Inhibitors; Virus Replication; Zidovudine

1990
Strength in numbers. Researchers begin combining compounds to fight AIDS.
    Scientific American, 1990, Volume: 263, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; CD4 Antigens; Didanosine; Drug Therapy, Combination; Humans; Interferons; Zalcitabine; Zidovudine

1990
Elimination of infectious human immunodeficiency virus from human T-cell cultures by synergistic action of CD4-Pseudomonas exotoxin and reverse transcriptase inhibitors.
    Proceedings of the National Academy of Sciences of the United States of America, 1990, Volume: 87, Issue:22

    Topics: ADP Ribose Transferases; Bacterial Toxins; CD4 Antigens; Cells, Cultured; Didanosine; Drug Synergism; Exotoxins; HIV; HIV Infections; Humans; Immunotoxins; In Vitro Techniques; Pseudomonas aeruginosa Exotoxin A; Reverse Transcriptase Inhibitors; T-Lymphocytes; Virulence Factors; Virus Replication; Zidovudine

1990
Detection of human immunodeficiency virus type 1 clinical isolates with reduced sensitivity to zidovudine and dideoxyinosine by RNA.RNA hybridization.
    Proceedings of the National Academy of Sciences of the United States of America, 1991, Apr-15, Volume: 88, Issue:8

    Topics: Cloning, Molecular; Didanosine; HIV-1; Humans; In Vitro Techniques; Leukocytes, Mononuclear; Microbial Sensitivity Tests; Nucleic Acid Hybridization; Reverse Transcriptase Inhibitors; RNA Probes; RNA-Directed DNA Polymerase; RNA, Viral; Sequence Homology, Nucleic Acid; Zidovudine

1991
Anti-human immunodeficiency virus synergism by zidovudine (3'-azidothymidine) and didanosine (dideoxyinosine) contrasts with their additive inhibition of normal human marrow progenitor cells.
    Antimicrobial agents and chemotherapy, 1991, Volume: 35, Issue:2

    Topics: Bone Marrow; Bone Marrow Cells; Bone Marrow Diseases; Cell Division; Colony-Forming Units Assay; Didanosine; Drug Synergism; Erythroid Precursor Cells; HIV; Humans; In Vitro Techniques; RNA-Directed DNA Polymerase; Stem Cells; Zidovudine

1991
Two-drug combinations of zidovudine, didanosine, and recombinant interferon-alpha A inhibit replication of zidovudine-resistant human immunodeficiency virus type 1 synergistically in vitro.
    The Journal of infectious diseases, 1991, Volume: 164, Issue:4

    Topics: Base Sequence; Cells, Cultured; Codon; Didanosine; DNA, Viral; Drug Resistance, Microbial; Drug Synergism; Genotype; HIV-1; Humans; Interferon Type I; Leukocytes, Mononuclear; Molecular Sequence Data; Mutation; Recombinant Proteins; RNA-Directed DNA Polymerase; Virus Replication; Zidovudine

1991
Resistance to ddI and sensitivity to AZT induced by a mutation in HIV-1 reverse transcriptase.
    Science (New York, N.Y.), 1991, Sep-27, Volume: 253, Issue:5027

    Topics: Acquired Immunodeficiency Syndrome; Base Sequence; Didanosine; DNA, Viral; Drug Resistance, Microbial; Genotype; HIV-1; Humans; Molecular Sequence Data; Mutation; Oligodeoxyribonucleotides; RNA-Directed DNA Polymerase; Zidovudine

1991
[Inhibitors of HIV-1 reverse transcriptase and protease as chemotherapeutics for AIDS].
    Nihon rinsho. Japanese journal of clinical medicine, 1991, Volume: 49, Issue:9

    Topics: Acquired Immunodeficiency Syndrome; Animals; Antiviral Agents; Didanosine; HIV Protease Inhibitors; HIV Reverse Transcriptase; HIV-1; Humans; Reverse Transcriptase Inhibitors; Thymine; Zalcitabine; Zidovudine

1991
[Combination therapies with anti-retroviral agents in HIV and AIDS infections].
    Revista clinica espanola, 1991, Volume: 189, Issue:6

    Topics: Acquired Immunodeficiency Syndrome; Anti-Bacterial Agents; Didanosine; Drug Resistance, Microbial; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Interferons; Zalcitabine; Zidovudine

1991
In vitro selection of variants of human immunodeficiency virus type 1 resistant to 3'-azido-3'-deoxythymidine and 2',3'-dideoxyinosine.
    Journal of virology, 1992, Volume: 66, Issue:1

    Topics: Base Sequence; Cell Line; Cloning, Molecular; Didanosine; DNA, Viral; Drug Resistance, Microbial; HIV-1; Humans; Immunoblotting; Kinetics; Molecular Sequence Data; Mutation; Phenotype; Polymerase Chain Reaction; Viral Proteins; Virus Replication; Zidovudine

1992
In vitro inhibition studies of the glucuronidation of 3'-azido-3'-deoxythymidine catalysed by human liver UDP-glucuronosyl transferase.
    Biochemical pharmacology, 1992, Jan-22, Volume: 43, Issue:2

    Topics: Acquired Immunodeficiency Syndrome; Diazepam; Didanosine; Dose-Response Relationship, Drug; Flunitrazepam; Glucuronosyltransferase; Humans; Kinetics; Microsomes, Liver; Morphine; Naproxen; Zidovudine

1992
From the National Institutes of Health.
    JAMA, 1992, Mar-11, Volume: 267, Issue:10

    Topics: Acquired Immunodeficiency Syndrome; Child; Didanosine; HIV Infections; Humans; National Institutes of Health (U.S.); United States; Zidovudine

1992
DdI for AIDS patients intolerant to AZT.
    American pharmacy, 1991, Volume: NS31, Issue:12

    Topics: Acquired Immunodeficiency Syndrome; Contraindications; Didanosine; Drug Storage; Female; Humans; Infant; Pregnancy; Zidovudine

1991
Evaluation of HIV P24 antigen, beta 2-microglobulin, neopterin, soluble CD4, soluble CD8, and soluble interleukin-2 receptor levels in patients with AIDS or AIDS-related complex treated with 2',3'-dideoxyinosine (ddI).
    Journal of clinical laboratory analysis, 1991, Volume: 5, Issue:6

    Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Complex; beta 2-Microglobulin; Biopterins; CD4 Antigens; CD8 Antigens; Didanosine; Drug Tolerance; HIV Core Protein p24; Humans; Neopterin; Receptors, Interleukin-2; Solubility; Zidovudine

1991
Second AIDS drug approved for those who can't tolerate AZT.
    Oncology (Williston Park, N.Y.), 1991, Volume: 5, Issue:11

    Topics: Acquired Immunodeficiency Syndrome; Adult; Child; Didanosine; Drug Tolerance; Humans; Zidovudine

1991
Effect of anti-human immunodeficiency virus nucleoside analogs on mitochondrial DNA and its implication for delayed toxicity.
    Molecular pharmacology, 1991, Volume: 39, Issue:5

    Topics: Antiviral Agents; Cell Line; Cytarabine; Didanosine; Dideoxynucleosides; DNA, Mitochondrial; HIV; Humans; Lymphocyte Activation; Nucleosides; Stavudine; T-Lymphocytes; Zalcitabine; Zidovudine

1991
Human immunodeficiency virus infection of human lymph nodes in the SCID-hu mouse.
    Proceedings of the National Academy of Sciences of the United States of America, 1991, May-15, Volume: 88, Issue:10

    Topics: Animals; Antiviral Agents; Didanosine; DNA, Viral; HIV; HIV Infections; Humans; Immunohistochemistry; Immunologic Deficiency Syndromes; Lymph Nodes; Macrophages; Mice; Nucleic Acid Hybridization; Polymerase Chain Reaction; T-Lymphocytes; Transplantation, Heterologous; Zidovudine

1991
Inhibition of immune functions by antiviral drugs.
    The Journal of clinical investigation, 1991, Volume: 87, Issue:6

    Topics: Acyclovir; Antiviral Agents; Cell Cycle; Cells, Cultured; Concanavalin A; Didanosine; DNA; Ganciclovir; Humans; Immunity; In Vitro Techniques; Lymphocyte Activation; Lymphocytes; Proteins; Ribavirin; Zidovudine

1991
[Anti-retroviral therapy of HIV-infection. With preliminary results of the Swiss postmarketing surveillance of zidovudine].
    Schweizerische medizinische Wochenschrift, 1991, Apr-20, Volume: 121, Issue:16

    Topics: Didanosine; Hematologic Diseases; HIV Infections; Humans; Opportunistic Infections; Product Surveillance, Postmarketing; Switzerland; Zidovudine

1991
Availability of dideoxyinosine.
    American journal of hospital pharmacy, 1991, Volume: 48, Issue:6

    Topics: Clinical Protocols; Didanosine; Drugs, Investigational; HIV Infections; Humans; Zidovudine

1991
Antiretroviral treatment for children with human immunodeficiency virus infection.
    Pediatrics, 1991, Volume: 88, Issue:2

    Topics: Acquired Immunodeficiency Syndrome; Child; Didanosine; Drug Evaluation; Drug Tolerance; Humans; National Institutes of Health (U.S.); Research Design; Risk Factors; United States; Zidovudine

1991
The effect of various drugs on the glucuronidation of zidovudine (azidothymidine; AZT) by human liver microsomes.
    British journal of clinical pharmacology, 1991, Volume: 32, Issue:1

    Topics: Acetaminophen; Adolescent; Adult; Chromatography, High Pressure Liquid; Didanosine; Drug Interactions; Female; Glucuronosyltransferase; Humans; Male; Microsomes, Liver; Middle Aged; Salicylates; Sulfanilamide; Sulfanilamides; Zidovudine

1991
[Antiretroviral therapy in Switzerland 1991].
    Schweizerische medizinische Wochenschrift, 1991, Aug-24, Volume: 121, Issue:34

    Topics: Acquired Immunodeficiency Syndrome; Didanosine; HIV; Humans; RNA, Viral; Virus Replication; Zidovudine

1991
In vitro inhibition of hepatitis B virus replication by 2',3'-dideoxyguanosine, 2',3'-dideoxyinosine, and 3'-azido-2',3'-dideoxythymidine in 2.2.15 (PR) cells.
    The Journal of infectious diseases, 1991, Volume: 164, Issue:5

    Topics: Blotting, Southern; Cell Line; Didanosine; Dideoxynucleosides; DNA Replication; DNA, Viral; Hepatitis B virus; Humans; RNA, Viral; Time Factors; Virus Replication; Zidovudine

1991
Determination of 3'-azido-3'-deoxythymidine, 2',3'-dideoxycytidine, 3'-fluoro-3'-deoxythymidine and 2',3'-dideoxyinosine in biological samples by high-performance liquid chromatography.
    Journal of chromatography, 1990, Dec-14, Volume: 534

    Topics: Animals; Antiviral Agents; Chromatography, High Pressure Liquid; Didanosine; Dideoxynucleosides; Humans; Liver; Rats; Zalcitabine; Zidovudine

1990
Long-term toxicity/activity profile of 2',3'-dideoxyinosine in AIDS or AIDS-related complex.
    Lancet (London, England), 1990, Sep-01, Volume: 336, Issue:8714

    Topics: Acquired Immunodeficiency Syndrome; AIDS Dementia Complex; AIDS-Related Complex; CD4-Positive T-Lymphocytes; Didanosine; Drug Administration Schedule; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Leukocyte Count; Male; T-Lymphocytes, Regulatory; Zidovudine

1990
Clinical response to dideoxyinosine in patients with HIV infection resistant to zidovudine.
    The New England journal of medicine, 1990, Jul-26, Volume: 323, Issue:4

    Topics: Acquired Immunodeficiency Syndrome; Didanosine; Drug Resistance, Microbial; HIV; Humans; Zidovudine

1990
Methodological issues in AIDS clinical trials. Active control equivalence trials.
    Journal of acquired immune deficiency syndromes, 1990, Volume: 3 Suppl 2

    Topics: Acquired Immunodeficiency Syndrome; Didanosine; Humans; Placebos; Randomized Controlled Trials as Topic; Research Design; Zidovudine

1990
Drugs for HIV infection.
    The Medical letter on drugs and therapeutics, 1990, Feb-09, Volume: 31, Issue:811

    Topics: Didanosine; HIV Infections; Humans; Zalcitabine; Zidovudine

1990
Clinical trials of combination therapies for HIV infection. Rationale for development of multidrug therapy.
    Journal of acquired immune deficiency syndromes, 1990, Volume: 3 Suppl 2

    Topics: Acquired Immunodeficiency Syndrome; Didanosine; Drug Therapy, Combination; Humans; Zalcitabine; Zidovudine

1990
Testing of nucleoside analogues in cats infected with feline leukemia virus: a model.
    Intervirology, 1989, Volume: 30 Suppl 1

    Topics: Acquired Immunodeficiency Syndrome; Animals; Antibodies, Viral; Antiviral Agents; Cats; Cell Line; Didanosine; Dideoxyadenosine; Dideoxynucleosides; Disease Models, Animal; Drug Evaluation, Preclinical; Immunologic Deficiency Syndromes; Leukemia Virus, Feline; Leukemia, Experimental; Nucleosides; Specific Pathogen-Free Organisms; Virus Replication; Zalcitabine; Zidovudine

1989
[Antiretroviral treatment against HIV].
    Medicina clinica, 1995, Sep-30, Volume: 105, Issue:10

    Topics: Antiviral Agents; Didanosine; HIV Infections; Humans; Zalcitabine; Zidovudine

1995
HIV-1, the brain, and combination therapy.
    Lancet (London, England), 1995, Nov-11, Volume: 346, Issue:8985

    Topics: Adult; AIDS Dementia Complex; Antiviral Agents; Child; Didanosine; Drug Combinations; HIV-1; Humans; Lamivudine; Neuroprotective Agents; Stavudine; Zalcitabine; Zidovudine

1995
Influence of human granulocyte-macrophage colony stimulating factor/interleukin-3 fusion protein (PIXY321) on the hematopoietic toxicity associated with anti-viral drugs (zidovudine and didanosine) in vitro using normal human marrow cells.
    Life sciences, 1995, Volume: 57, Issue:18

    Topics: Antiviral Agents; Bone Marrow; Cells, Cultured; Didanosine; Dose-Response Relationship, Drug; Granulocyte-Macrophage Colony-Stimulating Factor; Growth Substances; Hematopoietic Stem Cells; Humans; In Vitro Techniques; Interleukin-3; Recombinant Fusion Proteins; Zidovudine

1995
Transmembrane P-glycoprotein (P-gp/P-170) in HIV infection: analysis of lymphocyte surface expression and drug-unrelated function.
    AIDS research and human retroviruses, 1995, Volume: 11, Issue:8

    Topics: Adult; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cells, Cultured; Didanosine; Female; HIV Seropositivity; Humans; Immunophenotyping; Interleukin-2; Lymphocyte Activation; Lymphocytes; Male; Phytohemagglutinins; Zalcitabine; Zidovudine

1995
Combined drugs may be better than zidovudine alone for immunocompromised adults infected with HIV-1.
    Communicable disease report. CDR weekly, 1995, Oct-20, Volume: 5, Issue:42

    Topics: Adult; Antiviral Agents; Clinical Trials as Topic; Didanosine; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Immunocompromised Host; Treatment Outcome; Zalcitabine; Zidovudine

1995
[AIDS therapy with reverse transcriptase inhibitors].
    Nihon rinsho. Japanese journal of clinical medicine, 1993, Volume: 51 Suppl

    Topics: Acquired Immunodeficiency Syndrome; Didanosine; Drug Therapy, Combination; Humans; Lamivudine; Reverse Transcriptase Inhibitors; Stavudine; Zalcitabine; Zidovudine

1993
[Perinatally acquired human immunodeficiency virus infection].
    Nihon rinsho. Japanese journal of clinical medicine, 1993, Volume: 51 Suppl

    Topics: Acquired Immunodeficiency Syndrome; Didanosine; Female; gamma-Globulins; Humans; Infant; Male; Pregnancy; Pregnancy Complications, Infectious; Zidovudine

1993
[HIV drug resistance and its genetic basis].
    Nihon rinsho. Japanese journal of clinical medicine, 1993, Volume: 51 Suppl

    Topics: Amino Acid Sequence; Codon; Didanosine; Drug Resistance, Microbial; HIV; Molecular Sequence Data; Mutation; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Zidovudine

1993
Differential antiviral activity of two TIBO derivatives against the human immunodeficiency and murine leukemia viruses alone and in combination with other anti-HIV agents.
    AIDS research and human retroviruses, 1993, Volume: 9, Issue:11

    Topics: Animals; Antiviral Agents; Benzodiazepines; Cell Line; Didanosine; Drug Synergism; HIV Reverse Transcriptase; HIV-1; HIV-2; Humans; Imidazoles; Mice; Rauscher Virus; Reverse Transcriptase Inhibitors; Virus Replication; Zidovudine

1993
A cost analysis of approved antiretroviral strategies in persons with advanced human immunodeficiency virus disease and zidovudine intolerance.
    Journal of acquired immune deficiency syndromes, 1994, Volume: 7, Issue:4

    Topics: Acquired Immunodeficiency Syndrome; Agranulocytosis; Algorithms; Anemia; Costs and Cost Analysis; Decision Support Techniques; Didanosine; Erythrocyte Transfusion; Erythropoietin; Granulocyte Colony-Stimulating Factor; Hematopoietic Cell Growth Factors; HIV Infections; Humans; Pancreatitis; Quality of Life; Zidovudine

1994
Identification of a mutation at codon 65 in the IKKK motif of reverse transcriptase that encodes human immunodeficiency virus resistance to 2',3'-dideoxycytidine and 2',3'-dideoxy-3'-thiacytidine.
    Antimicrobial agents and chemotherapy, 1994, Volume: 38, Issue:2

    Topics: Amino Acid Sequence; Base Sequence; Cloning, Molecular; Codon; Didanosine; DNA Primers; Drug Resistance, Microbial; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; RNA-Directed DNA Polymerase; Zalcitabine; Zidovudine

1994
Combinative interactions of a human immunodeficiency virus (HIV) Tat antagonist with HIV reverse transcriptase inhibitors and an HIV protease inhibitor.
    Antimicrobial agents and chemotherapy, 1994, Volume: 38, Issue:2

    Topics: Antiviral Agents; Benzodiazepines; Didanosine; Drug Synergism; Gene Products, tat; HeLa Cells; HIV; HIV Protease Inhibitors; Humans; Isoquinolines; Nevirapine; Pyridines; Pyrroles; Quinolines; Reverse Transcriptase Inhibitors; Saquinavir; tat Gene Products, Human Immunodeficiency Virus; Zalcitabine; Zidovudine

1994
Didanosine resistance in HIV-infected patients switched from zidovudine to didanosine monotherapy.
    Annals of internal medicine, 1994, Aug-15, Volume: 121, Issue:4

    Topics: CD4-Positive T-Lymphocytes; Codon; Didanosine; Drug Resistance, Microbial; Genes, Viral; HIV; HIV Infections; Humans; Leukocyte Count; Mutation; Retrospective Studies; RNA-Directed DNA Polymerase; RNA, Viral; Zidovudine

1994
Safety profile of didanosine among patients with advanced HIV disease who are intolerant to or deteriorate despite zidovudine therapy: results of the Canadian Open ddI Treatment Program.
    Journal of acquired immune deficiency syndromes, 1994, Volume: 7, Issue:9

    Topics: Adult; Amylases; Cause of Death; Cohort Studies; Didanosine; Drug Evaluation; Female; Follow-Up Studies; HIV Infections; Humans; Male; Pancreatitis; Peripheral Nervous System Diseases; Prospective Studies; Risk Factors; Safety; Survival Analysis; Treatment Failure; Zidovudine

1994
[Anti-HIV-therapy. Monotherapy with drugs delaying the course of the disease has limited effect].
    Lakartidningen, 1994, Jul-27, Volume: 91, Issue:30-31

    Topics: Acquired Immunodeficiency Syndrome; Didanosine; Dose-Response Relationship, Drug; Drug Therapy, Combination; HIV Infections; Humans; Palliative Care; Zalcitabine; Zidovudine

1994
Differential antiviral activities and intracellular metabolism of 3'-azido-3'-deoxythymidine and 2',3'-dideoxyinosine in human cells.
    Antimicrobial agents and chemotherapy, 1994, Volume: 38, Issue:7

    Topics: Antiviral Agents; Cells, Cultured; Chromatography, High Pressure Liquid; Didanosine; Humans; Leukemia Virus, Feline; Phosphorylation; Reverse Transcriptase Inhibitors; Virus Replication; Zidovudine

1994
Genotypic evolution of HIV-1 isolates from patients after a switch of therapy from zidovudine to didanosine.
    Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association, 1995, Apr-01, Volume: 8, Issue:4

    Topics: Base Sequence; Biological Evolution; Didanosine; DNA Primers; DNA, Viral; Drug Resistance, Microbial; Genotype; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Leukocytes, Mononuclear; Molecular Sequence Data; Mutation; Phenotype; Polymerase Chain Reaction; RNA-Directed DNA Polymerase; Zidovudine

1995
New tetrahydroimidazo[4,5,1-jk][1,4]-benzodiazepin-2(1H)-one and -thione derivatives are potent inhibitors of human immunodeficiency virus type 1 replication and are synergistic with 2',3'-dideoxynucleoside analogs.
    Antimicrobial agents and chemotherapy, 1994, Volume: 38, Issue:12

    Topics: Antiviral Agents; Benzodiazepines; Didanosine; Drug Synergism; HIV Reverse Transcriptase; HIV-1; Imidazoles; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Virus Replication; Zidovudine

1994
Comparison of selective polymerase chain reaction primers and differential probe hybridization of polymerase chain reaction products for determination of relative amounts of codon 215 mutant and wild-type HIV-1 populations.
    Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association, 1995, Jul-01, Volume: 9, Issue:3

    Topics: Base Sequence; Codon; Didanosine; DNA Primers; DNA Probes; DNA, Single-Stranded; Drug Resistance, Microbial; Drug Therapy, Combination; Genotype; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Molecular Sequence Data; Nucleic Acid Hybridization; Point Mutation; Polymerase Chain Reaction; RNA-Directed DNA Polymerase; RNA, Viral; Zidovudine

1995
The inhibition of human immunodeficiency virus type 1 in vitro by a non-nucleoside reverse transcriptase inhibitor MKC-442, alone and in combination with other anti-HIV compounds.
    Antiviral research, 1995, Volume: 26, Issue:2

    Topics: Antiviral Agents; Cells, Cultured; Cytotoxicity Tests, Immunologic; Didanosine; Drug Interactions; HIV Reverse Transcriptase; HIV-1; Humans; Indolizines; Isoquinolines; Leukocytes, Mononuclear; Molecular Structure; Nevirapine; Pyridines; Quinolines; Reverse Transcriptase Inhibitors; Saquinavir; Uracil; Zalcitabine; Zidovudine

1995
In vitro comparison of selected triple-drug combinations for suppression of HIV-1 replication: the Inter-Company Collaboration Protocol.
    Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association, 1995, Volume: 10 Suppl 2

    Topics: Antiviral Agents; Cell Line, Transformed; Cytopathogenic Effect, Viral; Didanosine; Drug Synergism; HIV Protease Inhibitors; HIV-1; Humans; Indinavir; Isoquinolines; Lamivudine; Nevirapine; Pyridines; Quinolines; Reverse Transcriptase Inhibitors; Saquinavir; Virus Replication; Zalcitabine; Zidovudine

1995
Other AIDS drug regimens beat AZT alone, reduce clinical progression and mortality.
    JAMA, 1995, Oct-18, Volume: 274, Issue:15

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Clinical Trials as Topic; Didanosine; Drug Therapy, Combination; Humans; Reverse Transcriptase Inhibitors; Zalcitabine; Zidovudine

1995
Combination superior to zidovudine in Delta trial.
    Lancet (London, England), 1995, Sep-30, Volume: 346, Issue:8979

    Topics: Antiviral Agents; Clinical Trials as Topic; Didanosine; Drug Therapy, Combination; HIV Infections; Humans; Zalcitabine; Zidovudine

1995
Drugs for AIDS and associated infections.
    The Medical letter on drugs and therapeutics, 1995, Oct-13, Volume: 37, Issue:959

    Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Opportunistic Infections; Amphotericin B; Antifungal Agents; Antiprotozoal Agents; Antiviral Agents; Atovaquone; Candidiasis, Oral; Clindamycin; Clotrimazole; Cryptosporidiosis; Cytomegalovirus Infections; Dapsone; Didanosine; Drug Combinations; Drug Therapy, Combination; Fluconazole; Flucytosine; Folic Acid Antagonists; Foscarnet; Glucuronates; Herpes Simplex; Herpes Zoster; Humans; Isoniazid; Itraconazole; Ketoconazole; Lamivudine; Mycobacterium avium-intracellulare Infection; Naphthoquinones; Nystatin; Pentamidine; Pneumocystis Infections; Pneumonia, Pneumocystis; Prednisone; Primaquine; Reverse Transcriptase Inhibitors; Stavudine; Syphilis; Toxoplasmosis; Trimetrexate; Tuberculosis; Zalcitabine; Zidovudine

1995
AZT combination trial shows positive results.
    Nature, 1995, Sep-28, Volume: 377, Issue:6547

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Clinical Trials as Topic; Didanosine; Drug Therapy, Combination; Humans; Zalcitabine; Zidovudine

1995
Confirmation for combination AIDS therapy.
    Science (New York, N.Y.), 1995, Oct-06, Volume: 270, Issue:5233

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Controlled Clinical Trials as Topic; Didanosine; Drug Therapy, Combination; Humans; Multicenter Studies as Topic; Reverse Transcriptase Inhibitors; Zalcitabine; Zidovudine

1995
Study shows two drugs are best for HIV infection.
    BMJ (Clinical research ed.), 1995, Sep-30, Volume: 311, Issue:7009

    Topics: Antiviral Agents; Clinical Trials as Topic; Didanosine; Drug Therapy, Combination; HIV Infections; Humans; Zalcitabine; Zidovudine

1995
Development of zidovudine resistance mutations in patients receiving prolonged didanosine monotherapy.
    The Journal of infectious diseases, 1995, Volume: 172, Issue:6

    Topics: Acquired Immunodeficiency Syndrome; Adult; Antiviral Agents; Base Sequence; Didanosine; Drug Resistance; Female; HIV Reverse Transcriptase; HIV-1; Humans; Male; Molecular Sequence Data; Mutation; RNA-Directed DNA Polymerase; Zidovudine

1995
Effect of zidovudine and didanosine treatment on heart function in children infected with human immunodeficiency virus.
    The Journal of pediatrics, 1995, Volume: 127, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Cardiomyopathies; CD4 Lymphocyte Count; Child, Preschool; Didanosine; Dose-Response Relationship, Drug; Echocardiography; Female; Heart; HIV; Humans; Infant; Infant, Newborn; Male; Medical Records; Retrospective Studies; Severity of Illness Index; Zalcitabine; Zidovudine

1995
Perspectives in drug therapy of HIV infection.
    Drugs, 1995, Volume: 49 Suppl 1

    Topics: Didanosine; Drug Administration Schedule; Drug Therapy, Combination; HIV Infections; Humans; Time Factors; Zidovudine

1995
Zidovudine regimen in pediatric AIDS trial halted, other regimens shown superior.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 1995, May-01, Volume: 52, Issue:9

    Topics: Acquired Immunodeficiency Syndrome; Adolescent; Child; Child, Preschool; Clinical Trials as Topic; Didanosine; Disease Progression; Drug Therapy, Combination; Humans; Infant; Zidovudine

1995
Increased human immunodeficiency virus (HIV) type 1 DNA content and quinolinic acid concentration in brain tissues from patients with HIV encephalopathy.
    The Journal of infectious diseases, 1995, Volume: 172, Issue:3

    Topics: Adolescent; Adult; AIDS Dementia Complex; AIDS-Related Opportunistic Infections; Base Sequence; Brain; Brain Chemistry; Cells, Cultured; Cerebellum; Child; Child, Preschool; Didanosine; DNA Primers; DNA, Viral; Genes, pol; HIV-1; Humans; Infant; Macrophages; Middle Aged; Molecular Sequence Data; Mutation; Organ Specificity; Polymerase Chain Reaction; Quinolinic Acid; Tumor Necrosis Factor-alpha; Zidovudine

1995
Chemotherapeutic options in HIV infection.
    Advances in experimental medicine and biology, 1994, Volume: 370

    Topics: Analysis of Variance; Antiviral Agents; Biotransformation; Cell Line; Cells, Cultured; Chromatography, High Pressure Liquid; Didanosine; Drug Interactions; HIV Infections; HIV Seropositivity; HIV-1; Humans; Lymphocytes; Microbial Sensitivity Tests; Tumor Cells, Cultured; Zidovudine

1994
Disparate actions of hydroxyurea in potentiation of purine and pyrimidine 2',3'-dideoxynucleoside activities against replication of human immunodeficiency virus.
    Proceedings of the National Academy of Sciences of the United States of America, 1995, Aug-29, Volume: 92, Issue:18

    Topics: Adenosine Kinase; Cells, Cultured; Didanosine; DNA Replication; Drug Synergism; HIV-1; Humans; Hydroxyurea; Phosphorylation; Proviruses; Uridine Kinase; Virus Replication; Zalcitabine; Zidovudine

1995
Use of evolutionary limitations of HIV-1 multidrug resistance to optimize therapy.
    Nature, 1993, Feb-18, Volume: 361, Issue:6413

    Topics: Acquired Immunodeficiency Syndrome; Biological Evolution; Didanosine; DNA, Viral; Drug Resistance, Microbial; Drug Therapy, Combination; HIV Reverse Transcriptase; HIV-1; Humans; Mutation; Nevirapine; Polymerase Chain Reaction; Pyridines; Pyridones; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Selection, Genetic; Virus Replication; Zidovudine

1993
Triple whammy. Will an AIDS therapy live up to its advance billing?
    Scientific American, 1993, Volume: 268, Issue:5

    Topics: Acquired Immunodeficiency Syndrome; Cells, Cultured; Didanosine; Drug Therapy, Combination; HIV; Humans; Nevirapine; Pyridines; Pyridones; Reverse Transcriptase Inhibitors; Virus Replication; Zidovudine

1993
Inhibition of human immunodeficiency virus type 1 replication in vitro by the bisheteroarylpiperazine atevirdine (U-87201E) in combination with zidovudine or didanosine.
    The Journal of infectious diseases, 1993, Volume: 168, Issue:2

    Topics: Antiviral Agents; Cells, Cultured; Didanosine; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Microbial Sensitivity Tests; Piperazines; Reverse Transcriptase Inhibitors; Virus Replication; Zidovudine

1993
AIDS drugs. Harvard group makes a splash--twice.
    Science (New York, N.Y.), 1993, Aug-06, Volume: 261, Issue:5122

    Topics: Antiviral Agents; Didanosine; HIV; Mutation; Nevirapine; Pyridines; Reverse Transcriptase Inhibitors; Virus Replication; Zidovudine

1993
Resisting the temptation.
    Lancet (London, England), 1993, Aug-21, Volume: 342, Issue:8869

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Clinical Trials as Topic; Didanosine; Drug Combinations; HIV; Humans; Nevirapine; Pyridines; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Virus Replication; Zidovudine

1993
HIV and multidrug resistance.
    Nature, 1993, Aug-19, Volume: 364, Issue:6439

    Topics: Acquired Immunodeficiency Syndrome; Didanosine; Drug Resistance, Microbial; HIV Reverse Transcriptase; HIV-1; Humans; Mutation; Reverse Transcriptase Inhibitors; Zidovudine

1993
Effect of resistance on combination chemotherapy for human immunodeficiency virus infection.
    Advances in enzyme regulation, 1993, Volume: 33

    Topics: Antiviral Agents; Didanosine; Dideoxynucleosides; Drug Resistance, Microbial; Drug Therapy, Combination; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Microbial Sensitivity Tests; RNA-Directed DNA Polymerase; Virus Replication; Zidovudine

1993
Evaluation of the combination effect of different antiviral compounds against HIV in vitro.
    Scandinavian journal of infectious diseases, 1993, Volume: 25, Issue:3

    Topics: Antiviral Agents; Benzodiazepines; Didanosine; Dideoxynucleosides; Drug Combinations; Drug Evaluation; Drug Synergism; HIV; Humans; Imidazoles; Microbial Sensitivity Tests; Reverse Transcriptase Inhibitors; Stavudine; Zidovudine

1993
pol mutations conferring zidovudine and didanosine resistance with different effects in vitro yield multiply resistant human immunodeficiency virus type 1 isolates in vivo.
    Antimicrobial agents and chemotherapy, 1993, Volume: 37, Issue:7

    Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Complex; Didanosine; Drug Resistance, Microbial; Genes, pol; Glutamine; HIV Reverse Transcriptase; HIV-1; Humans; Leucine; Microbial Sensitivity Tests; Mutation; Phenotype; Polymerase Chain Reaction; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Tyrosine; Valine; Zidovudine

1993
[A new AIDS drug in evaluation].
    Fortschritte der Medizin, 1993, Aug-30, Volume: 111, Issue:24

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Delavirdine; Didanosine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Humans; Indoles; Piperazines; Reverse Transcriptase Inhibitors; Zidovudine

1993
Convergent combination therapy can select viable multidrug-resistant HIV-1 in vitro.
    Nature, 1993, Sep-30, Volume: 365, Issue:6445

    Topics: Base Sequence; Didanosine; DNA, Viral; Drug Resistance, Microbial; HeLa Cells; HIV Reverse Transcriptase; HIV-1; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; Nevirapine; Pyridines; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Zidovudine

1993
Thiazolobenzimidazole: biological and biochemical anti-retroviral activity of a new nonnucleoside reverse transcriptase inhibitor.
    Antiviral research, 1993, Volume: 21, Issue:3

    Topics: Antiviral Agents; Base Sequence; Benzimidazoles; Cell Line; Didanosine; DNA, Single-Stranded; Drug Synergism; HIV Reverse Transcriptase; HIV-1; Humans; Leukemia Virus, Murine; Molecular Sequence Data; Molecular Structure; Reverse Transcriptase Inhibitors; Thiazoles; Zidovudine

1993
Rapid and precise quantification of HIV-1 RNA in plasma using a branched DNA signal amplification assay.
    Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association, 1995, Apr-15, Volume: 8, Issue:5

    Topics: Acyclovir; CD4 Lymphocyte Count; Didanosine; Disease Progression; DNA, Single-Stranded; Drug Therapy, Combination; Gene Amplification; Genes, pol; HIV Seropositivity; HIV-1; Humans; Longitudinal Studies; Nucleic Acid Hybridization; Oligonucleotide Probes; Reproducibility of Results; RNA, Viral; Sensitivity and Specificity; Zidovudine

1995
Quantitative molecular monitoring of human immunodeficiency virus type 1 activity during therapy with specific antiretroviral compounds.
    Journal of clinical microbiology, 1995, Volume: 33, Issue:1

    Topics: Amino Acid Sequence; Didanosine; DNA, Viral; Female; Genes, pol; HIV Infections; HIV-1; Humans; Leukocytes, Mononuclear; Male; Molecular Sequence Data; Mutagenesis; RNA, Viral; Sequence Analysis, DNA; Transcription, Genetic; Viremia; Zidovudine

1995
Identification of drug-related genotypic changes in HIV-1 from serum using the selective polymerase chain reaction.
    Antiviral research, 1994, Volume: 25, Issue:3-4

    Topics: Antiviral Agents; Base Sequence; Didanosine; DNA Primers; DNA, Viral; Efficiency; Evaluation Studies as Topic; Genes, pol; Genotype; HIV Infections; HIV-1; Humans; Leukocytes, Mononuclear; Molecular Sequence Data; Mutation; Polymerase Chain Reaction; Proviruses; Reproducibility of Results; RNA, Viral; Sensitivity and Specificity; Templates, Genetic; Virion; Zalcitabine; Zidovudine

1994
Specific, sensitive, and rapid assay for human immunodeficiency virus type 1 pol mutations associated with resistance to zidovudine and didanosine.
    Journal of clinical microbiology, 1995, Volume: 33, Issue:2

    Topics: Base Sequence; Didanosine; DNA Ligases; DNA Primers; DNA Probes; DNA, Viral; Drug Resistance, Microbial; Evaluation Studies as Topic; Genes, pol; HIV Infections; HIV-1; Humans; Molecular Sequence Data; Mutation; Polymerase Chain Reaction; Sensitivity and Specificity; Time Factors; Virology; Zidovudine

1995
Treatment of children with HIV infection. PENTA (Paediatric European Network for Treatment of AIDS)
    Lancet (London, England), 1995, Apr-29, Volume: 345, Issue:8957

    Topics: Child; Clinical Trials as Topic; Didanosine; Drug Therapy, Combination; HIV Infections; Humans; Zidovudine

1995
Effects of the Th1 and Th2 stimulatory cytokines interleukin-12 and interleukin-4 on human immunodeficiency virus replication.
    Blood, 1995, Apr-15, Volume: 85, Issue:8

    Topics: Antibodies, Monoclonal; Cells, Cultured; Cytopathogenic Effect, Viral; Didanosine; HIV Core Protein p24; HIV-1; Humans; Interleukin-12; Interleukin-4; Interleukins; Leukocytes, Mononuclear; Lymphocyte Activation; Macrophages; Monocytes; Muromonab-CD3; Phytohemagglutinins; T-Lymphocytes, Helper-Inducer; Virus Replication; Zalcitabine; Zidovudine

1995
Effect of zidovudine on transplacental pharmacokinetics of ddI in the pigtailed macaque (Macaca nemestrina).
    Antimicrobial agents and chemotherapy, 1995, Volume: 39, Issue:2

    Topics: Animals; Didanosine; Drug Interactions; Female; Macaca nemestrina; Maternal-Fetal Exchange; Metabolic Clearance Rate; Placenta; Pregnancy; Zidovudine

1995
Determination of human immunodeficiency virus RNA in plasma and cellular viral DNA genotypic zidovudine resistance and viral load during zidovudine-didanosine combination therapy.
    Journal of virology, 1995, Volume: 69, Issue:6

    Topics: Base Sequence; Didanosine; DNA, Viral; Drug Resistance, Microbial; Drug Therapy, Combination; Genotype; HIV; HIV Infections; Humans; Molecular Sequence Data; RNA, Viral; Zidovudine

1995
Study of AZT effectiveness in treating HIV-infected children halted.
    The Journal of the American Osteopathic Association, 1995, Volume: 95, Issue:3

    Topics: Adolescent; Child; Child, Preschool; Didanosine; Drug Therapy, Combination; HIV Infections; Humans; Infant; Treatment Outcome; Zidovudine

1995
The effect of zidovudine and 2'3'-dideoxyinosine on human trophoblast in culture.
    Pharmacology & toxicology, 1995, Volume: 76, Issue:1

    Topics: Analysis of Variance; Cells, Cultured; Chorionic Gonadotropin; Didanosine; Energy Metabolism; Female; Humans; Pregnancy; Pregnancy Proteins; Pregnancy Trimester, First; Pregnancy Trimester, Third; Progesterone; Trophoblasts; Zidovudine

1995
[Use of an apoptosis test in the biological follow up of patients infected with HIV].
    Dakar medical, 1993, Volume: 38, Issue:2

    Topics: Apoptosis; CD4 Lymphocyte Count; Cells, Cultured; Didanosine; HIV Infections; Humans; Lymphocytes; Zidovudine

1993
Synergistic effect of recombinant CD4-immunoglobulin in combination with azidothymidine, dideoxyinosine and 0.5 beta-monoclonal antibody on human immunodeficiency virus infection in vitro.
    Letters in applied microbiology, 1994, Volume: 19, Issue:1

    Topics: Anti-Bacterial Agents; Antibodies, Monoclonal; CD4 Immunoadhesins; Cells, Cultured; Didanosine; Drug Synergism; Drug Therapy, Combination; HIV Infections; Humans; Lymphocytes; Zidovudine

1994
Community treatment of HIV-1: initial stage and asymptotic dynamics.
    Bio Systems, 1995, Volume: 35, Issue:1

    Topics: Community Health Services; Didanosine; HIV Infections; HIV-1; Humans; Male; Mathematics; Models, Biological; Zidovudine

1995
Stabilities of quantitative plasma culture for human immunodeficiency virus, RNA, and p24 antigen from samples collected in VACUTAINER CPT and standard VACUTAINER tubes.
    Journal of clinical microbiology, 1994, Volume: 32, Issue:9

    Topics: Anticoagulants; Blood Specimen Collection; CD4 Lymphocyte Count; Culture Media; Didanosine; DNA, Viral; Drug Therapy, Combination; Enzyme-Linked Immunosorbent Assay; Evaluation Studies as Topic; False Negative Reactions; Gels; HIV Core Protein p24; HIV Infections; HIV-1; Humans; Polyesters; Polymerase Chain Reaction; Predictive Value of Tests; RNA, Viral; Severity of Illness Index; Specimen Handling; Viremia; Virus Cultivation; Zidovudine

1994
Increased hematopoietic toxicity following administration of interferon-a with combination dideoxynucleoside therapy (zidovudine plus ddI) administered in normal mice.
    Life sciences, 1995, Volume: 56, Issue:3

    Topics: Animals; Bone Marrow; Didanosine; Dose-Response Relationship, Drug; Drug Synergism; Female; Interferon-alpha; Mice; Mice, Inbred C57BL; Spleen; Zidovudine

1995
Transfer of dideoxyinosine across the human isolated placenta.
    British journal of clinical pharmacology, 1994, Volume: 38, Issue:3

    Topics: Antipyrine; Biological Transport; Chromatography, High Pressure Liquid; Didanosine; Female; Glucose; Humans; Hydrogen-Ion Concentration; Hypoxanthine; Hypoxanthines; In Vitro Techniques; Inosine; Maternal-Fetal Exchange; Perfusion; Placenta; Pregnancy; Uric Acid; Zidovudine

1994
Effects of dideoxyinosine and dideoxycytidine on the intracellular phosphorylation of zidovudine in human mononuclear cells.
    British journal of clinical pharmacology, 1994, Volume: 38, Issue:4

    Topics: Analysis of Variance; B-Lymphocytes; Cell Line; Cells, Cultured; Didanosine; Drug Interactions; Humans; Leukocytes, Mononuclear; Lymphocyte Activation; Phosphorylation; Phytohemagglutinins; Thymidine; Zalcitabine; Zidovudine

1994
A direct, general approach based on isobolograms for assessing the joint action of drugs in pre-clinical experiments.
    Statistics in medicine, 1994, Nov-30, Volume: 13, Issue:22

    Topics: Didanosine; Dose-Response Relationship, Drug; Drug Antagonism; Drug Combinations; Drug Evaluation, Preclinical; Drug Interactions; Drug Synergism; HIV-1; Humans; Models, Theoretical; Zidovudine

1994
Early and prolonged decrease of viremia in HIV-1-infected patients treated with didanosine.
    Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association, 1995, Apr-01, Volume: 8, Issue:4

    Topics: AIDS-Related Opportunistic Infections; CD4 Lymphocyte Count; Didanosine; DNA, Viral; HIV Core Protein p24; HIV Infections; HIV-1; Humans; Polymerase Chain Reaction; Proviruses; RNA, Viral; Viremia; Virion; Zidovudine

1995
Comparison of the sensitivities of primary isolates of HIV type 2 and HIV type 1 to antiviral drugs and drug combinations.
    AIDS research and human retroviruses, 1994, Volume: 10, Issue:12

    Topics: Acquired Immunodeficiency Syndrome; Cells, Cultured; Didanosine; Dideoxynucleosides; Drug Synergism; HIV-1; HIV-2; Humans; Leukocytes, Mononuclear; Zidovudine

1994
In vivo inhibition of syncytium-inducing variants of HIV in patients treated with didanosine.
    AIDS (London, England), 1995, Volume: 9, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Didanosine; Giant Cells; HIV Infections; HIV-1; Humans; Phenotype; Prospective Studies; Zidovudine

1995
In-vitro activity of zidovudine, zalcitabine, and didanosine against mycoplasmas.
    Lancet (London, England), 1993, Nov-13, Volume: 342, Issue:8881

    Topics: Didanosine; In Vitro Techniques; Microbial Sensitivity Tests; Mycoplasma; Zalcitabine; Zidovudine

1993
Transfusion of blood components to persons infected with human immunodeficiency virus type 1: relationship to opportunistic infection.
    Transfusion, 1994, Volume: 34, Issue:1

    Topics: AIDS-Related Opportunistic Infections; Blood Component Transfusion; Blood Group Antigens; CD4-CD8 Ratio; CD4-Positive T-Lymphocytes; Cell Count; Cytomegalovirus Infections; Didanosine; Erythrocyte Transfusion; Female; HIV-1; Humans; Isoantibodies; Male; Mycobacterium avium-intracellulare Infection; Retrospective Studies; Risk Factors; Zalcitabine; Zidovudine

1994
Antiretroviral therapy in HIV-infected adults. Which regimens are recommended?
    Postgraduate medicine, 1994, Volume: 95, Issue:1

    Topics: Adult; CD4-Positive T-Lymphocytes; Didanosine; Drug Administration Schedule; Drug Resistance; Drug Therapy, Combination; HIV Infections; Humans; Leukocyte Count; Zalcitabine; Zidovudine

1994
Quantitation of human immunodeficiency virus by culture and polymerase chain reaction in response to didanosine after long-term therapy with zidovudine.
    The Journal of infectious diseases, 1994, Volume: 169, Issue:2

    Topics: Adult; CD4-Positive T-Lymphocytes; Didanosine; DNA, Viral; HIV Core Protein p24; HIV Infections; HIV Seropositivity; Humans; Leukocyte Count; Middle Aged; Polymerase Chain Reaction; Proviruses; RNA, Viral; Time Factors; Zidovudine

1994
Dynamics of molecular parameters of human immunodeficiency virus type 1 activity in vivo.
    Journal of virology, 1994, Volume: 68, Issue:4

    Topics: Acquired Immunodeficiency Syndrome; Adult; CD4-Positive T-Lymphocytes; Didanosine; Female; HIV Infections; HIV Seropositivity; HIV-1; Humans; Leukocytes, Mononuclear; Male; Middle Aged; Polymerase Chain Reaction; Proviruses; RNA, Viral; Time Factors; Transcription, Genetic; Zidovudine

1994
Suppression of HIV production in resting lymphocytes by combining didanosine and hydroxamate compounds.
    Lancet (London, England), 1994, May-21, Volume: 343, Issue:8908

    Topics: Cell Division; Cytopathogenic Effect, Viral; Didanosine; Drug Synergism; HIV-1; Humans; Interphase; Lymphocytes; Virus Replication; Zalcitabine; Zidovudine

1994
Quasispecies dynamics and the emergence of drug resistance during zidovudine therapy of HIV infection.
    AIDS (London, England), 1994, Volume: 8, Issue:3

    Topics: CD4-Positive T-Lymphocytes; Didanosine; Drug Resistance, Microbial; Drug Therapy, Combination; Genes, pol; HIV; HIV Infections; Humans; Leukocyte Count; Models, Biological; Mutation; Population Dynamics; Species Specificity; Virus Replication; Zidovudine

1994
Preferential incorporation of nucleoside analogs after template switching during human immunodeficiency virus reverse transcription.
    Antimicrobial agents and chemotherapy, 1994, Volume: 38, Issue:5

    Topics: Antiviral Agents; Base Sequence; CD4-Positive T-Lymphocytes; Cell Line; Didanosine; Dideoxynucleotides; DNA, Viral; HIV-1; Humans; Molecular Sequence Data; Nucleosides; Polymerase Chain Reaction; RNA, Transfer, Lys; Templates, Genetic; Thymine Nucleotides; Transcription, Genetic; Zidovudine

1994
Lower socioeconomic status and shorter survival following HIV infection.
    Lancet (London, England), 1994, Oct-22, Volume: 344, Issue:8930

    Topics: Acquired Immunodeficiency Syndrome; Adult; British Columbia; CD4 Lymphocyte Count; Cohort Studies; Didanosine; Health Services; HIV Infections; HIV Seropositivity; Homosexuality, Male; Humans; Income; Male; Pneumonia, Pneumocystis; Regression Analysis; Socioeconomic Factors; Survival Rate; Zalcitabine; Zidovudine

1994
[HIV infection--current possibilities in antiviral therapy].
    Therapeutische Umschau. Revue therapeutique, 1994, Volume: 51, Issue:8

    Topics: Antiviral Agents; Didanosine; Drug Therapy, Combination; HIV Infections; Humans; Pancreatitis; Zalcitabine; Zidovudine

1994
Anti-human immunodeficiency virus type 1 activity of hydroxyurea in combination with 2',3'-dideoxynucleosides.
    Molecular pharmacology, 1994, Volume: 46, Issue:4

    Topics: Antiviral Agents; Cells, Cultured; Didanosine; Dideoxynucleosides; Drug Synergism; HIV-1; Humans; Hydroxyurea; Virus Replication; Zalcitabine; Zidovudine

1994
Synergistic anti-human immunodeficiency virus type 1 effect of hydroxamate compounds with 2',3'-dideoxyinosine in infected resting human lymphocytes.
    Proceedings of the National Academy of Sciences of the United States of America, 1994, Nov-08, Volume: 91, Issue:23

    Topics: Antiviral Agents; Asparagine; Aspartic Acid; Cell Survival; Cells, Cultured; Didanosine; Drug Synergism; HIV Infections; Humans; Hydroxyurea; In Vitro Techniques; Lymphocyte Activation; Lymphocytes; Virus Replication; Zalcitabine; Zidovudine

1994
Hydroxyurea as an inhibitor of human immunodeficiency virus-type 1 replication.
    Science (New York, N.Y.), 1994, Nov-04, Volume: 266, Issue:5186

    Topics: Acquired Immunodeficiency Syndrome; Cell Survival; Didanosine; DNA Replication; DNA, Viral; Dose-Response Relationship, Drug; Drug Synergism; HIV Core Protein p24; HIV-1; Humans; Hydroxyurea; Leukocytes, Mononuclear; Lymphocyte Activation; Macrophage Activation; Macrophages; Virus Replication; Zidovudine

1994
MT-2 cell tropism of human immunodeficiency virus type 1 isolates as a marker for response to treatment and development of drug resistance.
    The Journal of infectious diseases, 1994, Volume: 170, Issue:6

    Topics: Adult; Biomarkers; CD4 Lymphocyte Count; Cell Line; Didanosine; Disease Progression; Drug Resistance, Microbial; Female; HIV Infections; HIV-1; Humans; Male; Prognosis; Virus Replication; Zidovudine

1994
Generation of multiple drug resistance by sequential in vitro passage of the human immunodeficiency virus type 1.
    Archives of virology, 1994, Volume: 136, Issue:1-2

    Topics: Antiviral Agents; Cell Line; Cloning, Molecular; Didanosine; Drug Interactions; Drug Resistance, Microbial; HIV-1; Humans; Interferon-alpha; Neutralization Tests; Phenotype; Serial Passage; Stavudine; Zalcitabine; Zidovudine

1994
[Current developments in antiviral chemotherapy. Part 4: Foscarnet, zidovudine, didanosine].
    Fortschritte der Medizin, 1994, May-10, Volume: 112, Issue:13

    Topics: AIDS-Related Opportunistic Infections; Didanosine; Dose-Response Relationship, Drug; Drug Administration Schedule; Foscarnet; Herpesviridae Infections; HIV Infections; Humans; Zidovudine

1994
Hyperosmolar nonketotic diabetic syndrome following treatment of human immunodeficiency virus infection with didanosine.
    Diabetes care, 1994, Volume: 17, Issue:4

    Topics: Adult; Blood Glucose; Didanosine; Female; HIV Infections; HIV Seropositivity; Humans; Hyperglycemia; Hyperglycemic Hyperosmolar Nonketotic Coma; Monitoring, Physiologic; Pregnancy; Pregnancy Complications, Infectious; Pregnancy in Diabetics; Zidovudine

1994
[The anti-viral agents used in the treatment of AIDS].
    Soins; la revue de reference infirmiere, 1994, Issue:584

    Topics: Acquired Immunodeficiency Syndrome; Didanosine; Humans; Zalcitabine; Zidovudine

1994
Multiple-drug-resistant mutants of feline immunodeficiency virus selected with 2',3'-dideoxyinosine alone and in combination with 3'-azido-3'-deoxythymidine.
    Antimicrobial agents and chemotherapy, 1994, Volume: 38, Issue:4

    Topics: Animals; Antiviral Agents; Cats; Cells, Cultured; Didanosine; Drug Resistance, Microbial; Foscarnet; Immunodeficiency Virus, Feline; Mutation; Phenotype; Zalcitabine; Zidovudine

1994
Influence of interleukin-3 (IL-3) on the hematopoietic toxicity associated with combination anti-viral drugs (zidovudine and DDI) in vitro using retrovirus-infected bone marrow cells.
    International journal of immunopharmacology, 1994, Volume: 16, Issue:4

    Topics: Animals; Antiviral Agents; Bone Marrow; Bone Marrow Cells; Didanosine; Drug Interactions; Female; Hematopoiesis; Hematopoietic Stem Cells; Immunoglobulin M; Interleukin-3; Mice; Mice, Inbred C57BL; Retroviridae Infections; Stem Cells; Zidovudine

1994
Effect of 3'-azido-3'-deoxythymidine and 2',3'-dideoxyinosine on establishment of human immunodeficiency virus type 1 infection in cultured CD8+ lymphocytes.
    Antimicrobial agents and chemotherapy, 1994, Volume: 38, Issue:5

    Topics: Antibodies, Monoclonal; Base Sequence; CD8 Antigens; Cells, Cultured; Didanosine; DNA Probes; DNA, Viral; Flow Cytometry; HIV Infections; HIV-1; Humans; Lymphocytes; Molecular Sequence Data; Zidovudine

1994
In vitro susceptibility of clinical isolates of HIV-1 to XM323, a non-peptidyl HIV protease inhibitor.
    AIDS (London, England), 1994, Volume: 8, Issue:6

    Topics: Antiviral Agents; Azepines; Cells, Cultured; Didanosine; Giant Cells; HIV Protease Inhibitors; HIV-1; Humans; Microbial Sensitivity Tests; Species Specificity; Zalcitabine; Zidovudine

1994
[Investigation of AZT susceptibility of sequential HIV-1 isolates from patients treated with ddI after long-term therapy with AZT].
    Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases, 1994, Volume: 68, Issue:7

    Topics: Acquired Immunodeficiency Syndrome; Adolescent; Adult; Didanosine; Female; HIV-1; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Zidovudine

1994
Use of didanosine in zidovudine-intolerant patients infected with human immunodeficiency virus.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1993, Volume: 16 Suppl 1

    Topics: CD4-Positive T-Lymphocytes; Didanosine; HIV Core Protein p24; HIV Infections; Humans; Leukocyte Count; Male; Zidovudine

1993
Didanosine and ACTG 116A.
    Lancet (London, England), 1993, Feb-27, Volume: 341, Issue:8844

    Topics: Didanosine; HIV Infections; Humans; Zidovudine

1993
Measurement of HIV virus load and genotypic resistance by gene amplification in asymptomatic subjects treated with combination therapy.
    Journal of acquired immune deficiency syndromes, 1993, Volume: 6, Issue:4

    Topics: CD4-Positive T-Lymphocytes; Codon; Didanosine; Drug Therapy, Combination; Gene Amplification; Genes, Viral; HIV; HIV Infections; Humans; Leukocyte Count; RNA, Viral; Zidovudine

1993
Quantitation of unintegrated HIV-1 DNA in asymptomatic patients in the presence or absence of antiretroviral therapy.
    AIDS research and human retroviruses, 1993, Volume: 9, Issue:2

    Topics: Adult; Antiviral Agents; Biomarkers; CD4-Positive T-Lymphocytes; Didanosine; DNA, Viral; Female; HIV Core Protein p24; HIV Infections; HIV-1; Humans; Leukocyte Count; Male; Middle Aged; Zidovudine

1993
Didanosine (ddI) and zidovudine (ZDV) susceptibilities of human immunodeficiency virus (HIV) isolates from long-term recipients of ddI.
    Antiviral research, 1993, Volume: 20, Issue:4

    Topics: Acquired Immunodeficiency Syndrome; Adult; AIDS-Related Complex; Base Sequence; CD4-Positive T-Lymphocytes; Didanosine; DNA, Viral; Drug Resistance, Microbial; Female; Genes, pol; HIV Core Protein p24; HIV-1; Humans; Leukocyte Count; Male; Microbial Sensitivity Tests; Middle Aged; Molecular Sequence Data; Time Factors; Zidovudine

1993
The Concorde trial.
    Lancet (London, England), 1993, May-15, Volume: 341, Issue:8855

    Topics: Didanosine; HIV Infections; Humans; Time Factors; Zidovudine

1993
Parameters affecting the development of non-Hodgkin's lymphoma in patients with severe human immunodeficiency virus infection receiving antiretroviral therapy.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1993, Volume: 11, Issue:6

    Topics: CD4-Positive T-Lymphocytes; Didanosine; HIV Infections; Humans; Interleukin-6; Leukocyte Count; Lymphoma, AIDS-Related; Lymphoma, Non-Hodgkin; Risk Factors; Zidovudine

1993
What to do when zidovudine fails.
    The New England journal of medicine, 1994, Mar-10, Volume: 330, Issue:10

    Topics: Didanosine; HIV Infections; Humans; Zalcitabine; Zidovudine

1994
Prophylactic zalcitabine and interferon-alpha for a large-bore needlestick exposure to human immunodeficiency virus.
    Journal of acquired immune deficiency syndromes, 1994, Volume: 7, Issue:4

    Topics: Adult; Didanosine; Drug Resistance, Microbial; Drug Therapy, Combination; Female; HIV; HIV Infections; Humans; Infectious Disease Transmission, Patient-to-Professional; Interferon alpha-2; Interferon-alpha; Needlestick Injuries; Recombinant Proteins; Zalcitabine; Zidovudine

1994
Relationship between anti-p24 antibody levels and p24 antigenemia in HIV-infected patients.
    AIDS research and human retroviruses, 1993, Volume: 9, Issue:12

    Topics: Antigen-Antibody Complex; Didanosine; HIV Antibodies; HIV Core Protein p24; HIV Infections; Humans; Prognosis; Viremia; Zidovudine

1993
Intermittent therapy.
    Journal of acquired immune deficiency syndromes, 1994, Volume: 7, Issue:5

    Topics: Didanosine; Drug Therapy, Combination; HIV Infections; Humans; Zalcitabine; Zidovudine

1994
Efflux of zidovudine and 2',3'-dideoxyinosine out of the cerebrospinal fluid when administered alone and in combination to Macaca nemestrina.
    Pharmaceutical research, 1994, Volume: 11, Issue:2

    Topics: Animals; Antipyrine; Chromatography, High Pressure Liquid; Didanosine; Drug Interactions; Female; Macaca nemestrina; Male; Zidovudine

1994
Pharmacotherapy of HIV. APhA Editorial Board on Pharmaceutical Care for Patients with HIV Infection.
    American pharmacy, 1994, Volume: NS34, Issue:2

    Topics: Adult; CD4 Antigens; Didanosine; Drug Interactions; Drug Therapy, Combination; HIV Infections; Humans; Male; Pharmaceutical Services; Zalcitabine; Zidovudine

1994
Comparative embryonic cytotoxicity of antiretroviral nucleosides.
    The Journal of infectious diseases, 1994, Volume: 169, Issue:5

    Topics: Animals; Antiviral Agents; Culture Techniques; Didanosine; Embryo, Mammalian; HIV; Mice; Nucleosides; Stavudine; Zalcitabine; Zidovudine

1994
Divergent anti-human immunodeficiency virus activity and anabolic phosphorylation of 2',3'-dideoxynucleoside analogs in resting and activated human cells.
    The Journal of biological chemistry, 1994, Apr-29, Volume: 269, Issue:17

    Topics: Cells, Cultured; Deoxycytidine Kinase; Didanosine; Dideoxynucleosides; HIV-1; Humans; Monocytes; Phosphorylation; Phytohemagglutinins; Thymidine Kinase; Zidovudine

1994
The drugs 2',3'-dideoxyinosine (ddI) and 2',3'-dideoxycytidine (ddC) are safe alternatives in people with AIDS with zidovudine-induced myopathy.
    Journal of acquired immune deficiency syndromes, 1994, Volume: 7, Issue:6

    Topics: Acquired Immunodeficiency Syndrome; Didanosine; Humans; Male; Muscular Diseases; Zalcitabine; Zidovudine

1994
Decreased anti-human immunodeficiency virus type-1 activities of 2',3'-dideoxynucleoside analogs in MOLT-4 cell sublines resistant to 2',3'-dideoxynucleoside analogs.
    Acta virologica, 1993, Volume: 37, Issue:5

    Topics: Cell Line; Culture Media; Didanosine; Dideoxynucleosides; Drug Resistance, Microbial; HIV Core Protein p24; HIV Infections; HIV-1; Humans; Microscopy, Electron; Time Factors; Zalcitabine; Zidovudine

1993
Dideoxynucleoside resistance emerges with prolonged zidovudine monotherapy. The RV43 Study Group.
    Antimicrobial agents and chemotherapy, 1994, Volume: 38, Issue:2

    Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Complex; Didanosine; Drug Resistance, Microbial; HIV Seropositivity; HIV-1; Humans; Leukocytes, Mononuclear; Microbial Sensitivity Tests; Time Factors; Zalcitabine; Zidovudine

1994
Inactivation of HIV infectivity by the chlorite-oxygen reaction product tetrachlorodecaoxygen.
    AIDS (London, England), 1993, Volume: 7, Issue:9

    Topics: Antiviral Agents; Cells, Cultured; Chlorine; Didanosine; Drug Interactions; HIV Envelope Protein gp120; HIV-1; HIV-2; Humans; Oxides; Tumor Cells, Cultured; Virus Replication; Zidovudine

1993
Human immunodeficiency virus type 1 pol gene mutations in an AIDS patient treated with multiple antiretroviral drugs.
    Journal of virology, 1993, Volume: 67, Issue:12

    Topics: Acquired Immunodeficiency Syndrome; Amino Acid Sequence; Base Sequence; Consensus Sequence; Didanosine; Genes, pol; Genotype; HIV-1; Humans; Leukocytes, Mononuclear; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Point Mutation; Polymerase Chain Reaction; Sequence Homology, Amino Acid; Time Factors; Viral Plaque Assay; Zalcitabine; Zidovudine

1993
Regulation of megakaryocyte colony forming cell numbers and ploidy by dideoxynucleosides in immunodeficient mice.
    American journal of hematology, 1993, Volume: 44, Issue:4

    Topics: Animals; Bone Marrow; Colony-Forming Units Assay; Didanosine; Female; Hematocrit; Hematopoietic Stem Cells; Leukemia Virus, Murine; Megakaryocytes; Mice; Mice, Inbred C57BL; Murine Acquired Immunodeficiency Syndrome; Platelet Count; Ploidies; Spleen; Zalcitabine; Zidovudine

1993
[Treatment--medical management of HIV carrier].
    Nihon rinsho. Japanese journal of clinical medicine, 1993, Volume: 51 Suppl

    Topics: Accidents, Occupational; Adjuvants, Immunologic; AIDS-Related Opportunistic Infections; Animals; Carrier State; Didanosine; Female; HIV Infections; Humans; Immunologic Factors; Male; Needles; Pneumonia, Pneumocystis; Zidovudine

1993
[BRM and drug combination therapy of HIV carriers].
    Nihon rinsho. Japanese journal of clinical medicine, 1993, Volume: 51 Suppl

    Topics: Carrier State; Cytokines; Didanosine; Drug Therapy, Combination; Female; HIV Infections; Humans; Immunologic Factors; Male; Zidovudine

1993
[Early treatment in HIV infection].
    Nihon rinsho. Japanese journal of clinical medicine, 1993, Volume: 51 Suppl

    Topics: Acquired Immunodeficiency Syndrome; Carrier State; CD4 Antigens; Didanosine; HIV Infections; Humans; Zidovudine

1993
[Treatment by antiviral drugs of HIV-infected patients].
    Revue de pneumologie clinique, 1993, Volume: 49, Issue:2

    Topics: Acyclovir; Antiviral Agents; Clinical Trials as Topic; Didanosine; Drug Therapy, Combination; HIV Infections; Humans; Interferon-alpha; Zalcitabine; Zidovudine

1993
[AIDS: therapeutic changes in the second decade. Triple combination--HIV vaccination].
    Fortschritte der Medizin, 1993, May-30, Volume: 111, Issue:15

    Topics: Acquired Immunodeficiency Syndrome; AIDS Vaccines; Antiviral Agents; Cross-Sectional Studies; Didanosine; Drug Therapy, Combination; Germany; Humans; Incidence; Nevirapine; Pyridines; Zidovudine

1993
Treating HIV infection: what pharmacists need to know.
    American pharmacy, 1993, Volume: NS33, Issue:5

    Topics: Adult; AIDS-Related Opportunistic Infections; Didanosine; Education, Pharmacy, Continuing; Female; HIV Infections; Humans; Male; Middle Aged; Pharmacists; Risk Factors; Zidovudine

1993
HIV-related thrombocytopenia.
    The New England journal of medicine, 1993, Jun-17, Volume: 328, Issue:24

    Topics: Didanosine; HIV Infections; Humans; Recurrence; Thrombocytopenia; Zidovudine

1993
Changes in drug sensitivity of human immunodeficiency virus type 1 during therapy with azidothymidine, dideoxycytidine, and dideoxyinosine: an in vitro comparative study.
    Proceedings of the National Academy of Sciences of the United States of America, 1993, Jan-15, Volume: 90, Issue:2

    Topics: Acquired Immunodeficiency Syndrome; Amino Acid Sequence; Base Sequence; Didanosine; Dose-Response Relationship, Drug; Genetic Variation; HIV-1; Humans; Microbial Sensitivity Tests; Molecular Sequence Data; Sequence Homology, Amino Acid; Zalcitabine; Zidovudine

1993
Population-based estimates of antiretroviral therapy and anti-Pneumocystis prophylaxis in San Francisco: 1991.
    Journal of acquired immune deficiency syndromes, 1993, Volume: 6, Issue:2

    Topics: AIDS-Related Opportunistic Infections; Anti-Infective Agents; Antiviral Agents; Cohort Studies; Dapsone; Didanosine; Drug Combinations; Follow-Up Studies; HIV Infections; Humans; Male; Pentamidine; Pneumonia, Pneumocystis; San Francisco; Sulfamethizole; Trimethoprim; Zalcitabine; Zidovudine

1993
Antiretroviral therapy.
    The Journal of the Louisiana State Medical Society : official organ of the Louisiana State Medical Society, 1993, Volume: 145, Issue:3

    Topics: Didanosine; Dideoxynucleosides; HIV Infections; Humans; Zalcitabine; Zidovudine

1993
The use and toxicity of didanosine (ddI) in HIV antibody-positive individuals intolerant to zidovudine (AZT)
    The Quarterly journal of medicine, 1993, Volume: 86, Issue:3

    Topics: Acquired Immunodeficiency Syndrome; Adult; Aged; AIDS-Related Complex; Body Weight; Diarrhea; Didanosine; Female; HIV Core Protein p24; Humans; Leukocyte Count; Lymphocyte Subsets; Male; Middle Aged; Pancreatitis; Peripheral Nervous System Diseases; Quality of Life; Risk Factors; Zidovudine

1993
Differential phosphorylation of azidothymidine, dideoxycytidine, and dideoxyinosine in resting and activated peripheral blood mononuclear cells.
    The Journal of clinical investigation, 1993, Volume: 91, Issue:5

    Topics: 5'-Nucleotidase; Acquired Immunodeficiency Syndrome; Adenosine Kinase; AIDS-Related Complex; Chromatography, High Pressure Liquid; Deoxycytidine Kinase; Deoxyribonucleotides; Didanosine; HIV-1; Humans; Kinetics; Microbial Sensitivity Tests; Monocytes; Phosphorylation; Thymidine Kinase; Uridine Kinase; Zalcitabine; Zidovudine

1993
Mechanism of action of N-butyl deoxynojirimycin in inhibiting HIV-1 infection and activity in combination with nucleoside analogs.
    AIDS research and human retroviruses, 1993, Volume: 9, Issue:4

    Topics: 1-Deoxynojirimycin; Antiviral Agents; CD4 Antigens; Cell Line; Didanosine; Drug Interactions; HIV Envelope Protein gp120; HIV-1; Humans; Nucleosides; Zalcitabine; Zidovudine

1993
High-level resistance to zidovudine but not to zalcitabine or didanosine in human immunodeficiency virus from children receiving antiretroviral therapy.
    The Journal of pediatrics, 1993, Volume: 123, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Child; Child, Preschool; Didanosine; DNA, Viral; Drug Resistance, Microbial; Drug Therapy, Combination; HIV-1; Humans; Infant; Microbial Sensitivity Tests; Mutation; Polymerase Chain Reaction; Time Factors; Zalcitabine; Zidovudine

1993
Antiretroviral therapy and medical management of the human immunodeficiency virus-infected child. Working Group on Antiretroviral Therapy: National Pediatric HIV Resource Center.
    The Pediatric infectious disease journal, 1993, Volume: 12, Issue:6

    Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Child; Child, Preschool; Didanosine; HIV Infections; Humans; Immunoglobulins, Intravenous; Infant; Zalcitabine; Zidovudine

1993
A pilot study of sequential therapy with zidovudine plus acyclovir, dideoxyinosine, and dideoxycytidine in patients with severe human immunodeficiency virus infection.
    The Journal of infectious diseases, 1993, Volume: 168, Issue:4

    Topics: Acquired Immunodeficiency Syndrome; Acyclovir; Adult; AIDS-Related Complex; Antigens, CD; Biomarkers; Body Weight; CD4 Antigens; Didanosine; Drug Administration Schedule; Drug Therapy, Combination; HIV Core Protein p24; Humans; Male; Middle Aged; Pilot Projects; T-Lymphocyte Subsets; Time Factors; Zalcitabine; Zidovudine

1993
Preliminary study analysis suggests similar efficacy for didanosine and zalcitabine.
    Clinical pharmacy, 1993, Volume: 12, Issue:6

    Topics: Acquired Immunodeficiency Syndrome; Didanosine; Humans; Treatment Outcome; Zalcitabine; Zidovudine

1993
Antiretroviral treatment reverses HIV-induced reduction in the expression of surface antigens on alveolar macrophages in AIDS patients.
    Clinical and experimental immunology, 1993, Volume: 91, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Antigens, Surface; Didanosine; HLA-DR Antigens; Humans; Macrophages, Alveolar; Zidovudine

1993
Didanosine-associated eosinophilia with acute thrombocytopenia.
    The Annals of pharmacotherapy, 1993, Volume: 27, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Acute Disease; Adult; Didanosine; Eosinophilia; Humans; Male; Sarcoma, Kaposi; Thrombocytopenia; Zidovudine

1993
[Antiretroviral therapy].
    Revue medicale de Liege, 1993, Volume: 48, Issue:2

    Topics: Clinical Trials as Topic; Didanosine; HIV Infections; Humans; Zidovudine

1993
Comparison of dideoxynucleoside drugs (DDI and zidovudine) and induction of hematopoietic toxicity using normal human bone marrow cells in vitro.
    International journal of immunopharmacology, 1993, Volume: 15, Issue:2

    Topics: Bone Marrow; Bone Marrow Cells; Colony-Forming Units Assay; Didanosine; Dose-Response Relationship, Drug; Drug Interactions; Erythropoietin; Hematopoiesis; Hematopoietic Stem Cells; Humans; In Vitro Techniques; Zidovudine

1993
Using convergent combination therapy, researchers stopped the human immunodeficiency virus (HIV) from reproducing in test tubes.
    The Journal of the American Osteopathic Association, 1993, Volume: 93, Issue:4

    Topics: Didanosine; Drug Therapy, Combination; HIV Infections; Humans; In Vitro Techniques; Pyridones; Zidovudine

1993
Parvovirus B19 infection in human immunodeficiency virus type 1-infected persons failing or intolerant to zidovudine therapy.
    The Journal of infectious diseases, 1993, Volume: 168, Issue:1

    Topics: Adult; AIDS-Related Opportunistic Infections; Antibodies, Viral; Didanosine; Erythema Infectiosum; HIV Infections; Humans; Incidence; Male; Middle Aged; Parvovirus B19, Human; Zidovudine

1993
Population pharmacokinetics of didanosine in patients with human immunodeficiency virus infection.
    The Journal of infectious diseases, 1996, Volume: 173, Issue:1

    Topics: Antiviral Agents; Demography; Didanosine; HIV Infections; Humans; Zidovudine

1996
Transdermal delivery of dideoxynucleoside-type anti-HIV drugs. 1. Stability studies for hairless rat skin permeation.
    Journal of pharmaceutical sciences, 1995, Volume: 84, Issue:9

    Topics: Administration, Cutaneous; Animals; Anti-Infective Agents, Local; Antiviral Agents; Chromatography, High Pressure Liquid; Didanosine; Dideoxynucleosides; Enzyme Inhibitors; Female; Half-Life; HIV-1; In Vitro Techniques; Rats; Rats, Nude; Skin Absorption; Zalcitabine; Zidovudine

1995
Multidrug-resistant human immunodeficiency virus type 1 strains resulting from combination antiretroviral therapy.
    Journal of virology, 1996, Volume: 70, Issue:2

    Topics: Animals; Antiviral Agents; Base Sequence; Cell Line; Didanosine; DNA Primers; DNA, Viral; Drug Resistance, Microbial; Drug Resistance, Multiple; Drug Therapy, Combination; HeLa Cells; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Virus Replication; Zidovudine

1996
Effects of 3'-deoxynucleoside 5'-triphosphate concentrations on chain termination by nucleoside analogs during human immunodeficiency virus type 1 reverse transcription of minus-strand strong-stop DNA.
    Journal of virology, 1996, Volume: 70, Issue:2

    Topics: Antiviral Agents; Base Sequence; Cells, Cultured; Didanosine; Dideoxynucleotides; DNA, Viral; HIV-1; Humans; Lamivudine; Molecular Sequence Data; Nucleic Acid Conformation; Nucleosides; Nucleotides; Phytohemagglutinins; RNA, Viral; Thymine Nucleotides; Transcription, Genetic; Zalcitabine; Zidovudine

1996
Development of a human thymic organ culture model for the study of HIV pathogenesis.
    AIDS research and human retroviruses, 1995, Volume: 11, Issue:9

    Topics: Animals; Antiviral Agents; Apoptosis; Cats; CD4-CD8 Ratio; CD4-Positive T-Lymphocytes; Didanosine; Drug Evaluation, Preclinical; Fetus; HIV Infections; HIV-1; Humans; Mice; Models, Biological; Organ Culture Techniques; Thymus Gland; Time Factors; Virus Replication; Zidovudine

1995
Inhibitory effect of 3'-azido-3'-deoxythymidine on proliferative responsiveness of CD8+ lymphocytes to interleukin-2.
    Clinical and diagnostic laboratory immunology, 1994, Volume: 1, Issue:4

    Topics: Antiviral Agents; CD8-Positive T-Lymphocytes; Cell Division; Didanosine; Humans; Interleukin-2; Lamivudine; Lymphocyte Activation; Zalcitabine; Zidovudine

1994
Intracellular activation and cytotoxicity of three different combinations of 3'-azido-3'-deoxythymidine and 2',3'-dideoxyinosine.
    AIDS research and human retroviruses, 1995, Volume: 11, Issue:10

    Topics: Antiviral Agents; Cell Division; Cell Line; Didanosine; Dideoxynucleotides; Drug Interactions; Humans; Reverse Transcriptase Inhibitors; Thymine Nucleotides; Zidovudine

1995
Uptake and distribution of 2',3'-dideoxyinosine and its derivatives in a human monocytoid cell line.
    Cellular and molecular biology (Noisy-le-Grand, France), 1995, Volume: 41 Suppl 1

    Topics: Biological Transport; Biotransformation; Cell Division; Deoxyadenine Nucleotides; Didanosine; Dideoxynucleotides; DNA Damage; DNA Replication; DNA, Neoplasm; Humans; Lymphoma, Large B-Cell, Diffuse; Monocytes; RNA, Neoplasm; Tumor Cells, Cultured; Zidovudine

1995
In vitro anti-HIV-1 activity of HIV protease inhibitor KNI-272 in resting and activated cells: implications for its combined use with AZT or ddI.
    Antiviral research, 1995, Volume: 28, Issue:1

    Topics: Antiviral Agents; Cells, Cultured; Didanosine; Drug Interactions; HIV Protease Inhibitors; HIV-1; Humans; Leukocytes, Mononuclear; Molecular Structure; Oligopeptides; Phytohemagglutinins; Zidovudine

1995
Managing HIV disease after Delta.
    BMJ (Clinical research ed.), 1996, Mar-02, Volume: 312, Issue:7030

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Didanosine; Drug Combinations; HIV Infections; Humans; Randomized Controlled Trials as Topic; Zalcitabine; Zidovudine

1996
The mutation frequency of feline immunodeficiency virus enhanced by 3'-azido-3'-deoxythymidine.
    Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association, 1996, May-01, Volume: 12, Issue:1

    Topics: Animals; Antiviral Agents; Bromodeoxyuridine; Cats; Cell Line; Didanosine; Dose-Response Relationship, Drug; Gene Frequency; Immunodeficiency Virus, Feline; Kidney; Mutation; Virus Cultivation; Zalcitabine; Zidovudine

1996
Factors associated with changes in the use of antiretroviral therapy by a cohort of homosexual men infected with human immunodeficiency virus type 1.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1995, Volume: 21, Issue:4

    Topics: Antiviral Agents; CD4 Lymphocyte Count; Cohort Studies; Didanosine; Drug Therapy, Combination; Drug Utilization; Follow-Up Studies; Hemoglobins; HIV Infections; HIV-1; Homosexuality, Male; Humans; Male; Multicenter Studies as Topic; Reverse Transcriptase Inhibitors; Stavudine; Zalcitabine; Zidovudine

1995
In vitro inhibition of the replication of human immunodeficiency virus type 1 by beta-mercaptoethylamine (cysteamine).
    The Journal of infectious diseases, 1996, Volume: 174, Issue:1

    Topics: Antiviral Agents; Cell Death; Cells, Cultured; Cysteamine; Didanosine; DNA, Viral; Drug Therapy, Combination; HIV Core Protein p24; HIV-1; Humans; Macrophages; Monocytes; Polymerase Chain Reaction; Zidovudine

1996
[Pancreatic disease in patients with HIV treated with didanosine (DDI)].
    Revista espanola de enfermedades digestivas, 1996, Volume: 88, Issue:2

    Topics: Acute Disease; Antiviral Agents; CD4 Lymphocyte Count; Didanosine; Drug Therapy, Combination; Female; HIV Infections; Humans; Male; Pancreatic Diseases; Pancreatitis; Zidovudine

1996
Determination intestinal metabolism and permeability for several compounds in rats. Implications on regional bioavailability in humans.
    Pharmaceutical research, 1996, Volume: 13, Issue:1

    Topics: Animals; Biological Availability; Captopril; Didanosine; Humans; Intestine, Small; Male; Mannitol; Ofloxacin; Permeability; Rats; Rats, Sprague-Dawley; Zidovudine

1996
Transdermal delivery of dideoxynucleoside-type anti-HIV drugs. 2. The effect of vehicle and enhancer on skin permeation.
    Journal of pharmaceutical sciences, 1996, Volume: 85, Issue:2

    Topics: Animals; Antiviral Agents; Didanosine; Drug Delivery Systems; Female; Rats; Skin; Zalcitabine; Zidovudine

1996
Adverse events from drug therapy for human immunodeficiency virus disease.
    The American journal of medicine, 1996, Volume: 101, Issue:1

    Topics: Adult; Antiviral Agents; CD4 Lymphocyte Count; Dapsone; Didanosine; Female; HIV Infections; Humans; Male; Pneumonia, Pneumocystis; Risk Factors; Trimethoprim, Sulfamethoxazole Drug Combination; Urban Health; Zalcitabine; Zidovudine

1996
Didanosine (DDI) alone is now considered the first-line therapy for symptomatic children infected with the human immunodeficiency virus (HIV)
    The Journal of the American Osteopathic Association, 1996, Volume: 96, Issue:6

    Topics: Adolescent; Antiviral Agents; Child; Child, Preschool; Clinical Trials as Topic; Didanosine; HIV Infections; Humans; Infant; Zidovudine

1996
[Anti-retroviral monotherapy with nucleoside analogues].
    Revista da Sociedade Brasileira de Medicina Tropical, 1995, Volume: 28 Suppl 2

    Topics: Antiviral Agents; Didanosine; HIV Infections; Humans; Zalcitabine; Zidovudine

1995
Human immunodeficiency virus type 1 kinetics in lymph nodes compared with plasma.
    The Journal of infectious diseases, 1996, Volume: 174, Issue:2

    Topics: Antiviral Agents; Biopsy; Didanosine; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Kinetics; Lamivudine; Lymph Nodes; RNA, Viral; Viremia; Zalcitabine; Zidovudine

1996
Zidovudine resistance reverse transcriptase mutations during didanosine monotherapy.
    The Journal of infectious diseases, 1996, Volume: 174, Issue:2

    Topics: Didanosine; Drug Resistance, Microbial; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Male; Mutation; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Sequence Analysis; Zidovudine

1996
The data and safety monitoring board and acquired immune deficiency syndrome (AIDS) clinical trials.
    Controlled clinical trials, 1995, Volume: 16, Issue:6

    Topics: Advisory Committees; Anti-Infective Agents; Clinical Trials as Topic; Clinical Trials Data Monitoring Committees; Confidentiality; Conflict of Interest; Didanosine; Drug Evaluation; Federal Government; HIV Infections; Humans; National Institutes of Health (U.S.); Organizational Objectives; Professional Staff Committees; Pyrimethamine; Reverse Transcriptase Inhibitors; Risk Assessment; Toxoplasmosis, Cerebral; Treatment Outcome; United States; Zalcitabine; Zidovudine

1995
MDL 74,968, a new acyclonucleotide analog: activity against human immunodeficiency virus in vitro and in the hu-PBL-SCID.beige mouse model of infection.
    Antimicrobial agents and chemotherapy, 1996, Volume: 40, Issue:5

    Topics: Adenine; Animals; Antiviral Agents; Cell Line; Cells, Cultured; Didanosine; DNA, Viral; Guanine; HIV Infections; HIV-1; HIV-2; Humans; Male; Mice; Mice, SCID; Monocytes; Organophosphonates; Spleen; T-Lymphocytes; Zidovudine

1996
Synergistic inhibition of human immunodeficiency virus isolates (including 3'-azido-3'-deoxythymidine-resistant isolates) by foscarnet in combination with 2',3'-dideoxyinosine or 2',3'-dideoxycytidine.
    Antimicrobial agents and chemotherapy, 1996, Volume: 40, Issue:5

    Topics: Antiviral Agents; Cells, Cultured; Didanosine; Drug Combinations; Drug Resistance, Microbial; Drug Synergism; Foscarnet; HIV-1; Humans; Microbial Sensitivity Tests; Monocytes; Zalcitabine; Zidovudine

1996
Combination antiretroviral chemotherapy: a potential strategy in AIDS-related malignancy.
    Anti-cancer drugs, 1996, Volume: 7, Issue:1

    Topics: Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols; Antiviral Agents; Cell Division; Didanosine; HIV Infections; HL-60 Cells; Humans; Zalcitabine; Zidovudine

1996
Combination drug treatment benefits patients with HIV.
    BMJ (Clinical research ed.), 1996, Aug-10, Volume: 313, Issue:7053

    Topics: Antiviral Agents; Didanosine; Drug Combinations; HIV Infections; Humans; Zalcitabine; Zidovudine

1996
Acquisition of syncytium-inducing HIV-1 strains during therapy with zidovudine alone or combined with alpha interferon or didanosine.
    European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 1996, Volume: 15, Issue:4

    Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Didanosine; Drug Therapy, Combination; Female; Giant Cells; HIV Infections; HIV-1; Humans; Interferon-alpha; Male; Phenotype; Prospective Studies; Zidovudine

1996
[Prescription of antiretroviral and prophylactic drugs in HIV diseases: reality of medical practices].
    Annales de medecine interne, 1995, Volume: 146, Issue:7

    Topics: Anti-Infective Agents; Antiviral Agents; CD4 Lymphocyte Count; Dapsone; Didanosine; Drug Utilization; France; HIV Infections; Hospital Information Systems; Hospital Records; Humans; Pentamidine; Trimethoprim, Sulfamethoxazole Drug Combination; Zalcitabine; Zidovudine

1995
Protection of human immunodeficiency virus encephalitis by a switch from zidovudine to didanosine.
    Antimicrobial agents and chemotherapy, 1996, Volume: 40, Issue:1

    Topics: Didanosine; Encephalitis, Viral; HIV Infections; Humans; Retrospective Studies; Zidovudine

1996
Antiviral activities of nucleotide heterodimers against human immunodeficiency virus type 1 in vitro.
    Antiviral research, 1996, Volume: 31, Issue:1-2

    Topics: Anti-HIV Agents; Cell Line, Transformed; Cytopathogenic Effect, Viral; Didanosine; HIV-1; Humans; Ribavirin; Uracil; Zidovudine

1996
Comparison of virus burden in blood and sequential lymph node biopsy specimens from children infected with human immunodeficiency virus.
    The Journal of pediatrics, 1996, Volume: 129, Issue:3

    Topics: Antiviral Agents; Biopsy; CD4 Lymphocyte Count; Child; Child, Preschool; Didanosine; DNA, Viral; Drug Therapy, Combination; Female; HIV Core Protein p24; HIV Infections; HIV-1; Humans; In Situ Hybridization; Infant; Lymph Nodes; Male; Nevirapine; Pyridines; Viremia; Zidovudine

1996
Therapy of HIV infections: problems and prospects.
    Bulletin of the New York Academy of Medicine, 1996,Summer, Volume: 73, Issue:1

    Topics: Anti-HIV Agents; Didanosine; Drug Resistance, Microbial; HIV; HIV Infections; HIV Protease Inhibitors; Humans; Stavudine; Urban Health; Zalcitabine; Zidovudine

1996
Kinetics of viral clearance in plasma, peripheral blood mononuclear cells and lymph nodes.
    AIDS (London, England), 1996, Volume: 10, Issue:7

    Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Didanosine; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Lamivudine; Leukocytes, Mononuclear; Lymph Nodes; Male; Plasma; RNA, Viral; Time Factors; Zidovudine

1996
AZT-related mutation Lys70Arg in reverse transcriptase of human immunodeficiency virus type 1 confers decrease in susceptibility to ddATP in in vitro RT inhibition assay.
    Virology, 1996, Sep-15, Volume: 223, Issue:2

    Topics: Base Sequence; Didanosine; Drug Resistance, Microbial; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; Polymerase Chain Reaction; Proviruses; Reverse Transcriptase Inhibitors; Zidovudine

1996
Therapy for human immunodeficiency virus infection -- what have we learned?
    The New England journal of medicine, 1996, Oct-10, Volume: 335, Issue:15

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; CD4 Lymphocyte Count; Didanosine; Drug Therapy, Combination; HIV Infections; Humans; Zalcitabine; Zidovudine

1996
Human immunodeficiency virus reverse transcriptase codon 215 mutations diminish virologic response to didanosine-zidovudine therapy in subjects with non-syncytium-inducing phenotype.
    The Journal of infectious diseases, 1996, Volume: 174, Issue:4

    Topics: Acquired Immunodeficiency Syndrome; Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Codon; Didanosine; Drug Therapy, Combination; HIV Reverse Transcriptase; Humans; Male; Middle Aged; Mutation; Phenotype; RNA, Viral; Zidovudine

1996
Didanosine (ddl) and stavudine (d4T): absence of peripheral neurotoxicity in rabbits.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1995, Volume: 33, Issue:12

    Topics: Animals; Antiviral Agents; Didanosine; Male; Microscopy, Electron; Neural Conduction; Neurons; Peripheral Nerves; Rabbits; Sciatic Nerve; Spinal Nerves; Stavudine; Zidovudine

1995
Selection and characterization of a mutant of feline immunodeficiency virus resistant to 2',3'-dideoxycytidine.
    Antimicrobial agents and chemotherapy, 1996, Volume: 40, Issue:4

    Topics: Amino Acid Sequence; Animals; Antiviral Agents; Base Sequence; Cats; Cell Line; Didanosine; Drug Resistance, Microbial; Immunodeficiency Virus, Feline; Molecular Sequence Data; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Zalcitabine; Zidovudine

1996
Antiviral efficacy in vivo of the anti-human immunodeficiency virus bicyclam SDZ SID 791 (JM 3100), an inhibitor of infectious cell entry.
    Antimicrobial agents and chemotherapy, 1996, Volume: 40, Issue:3

    Topics: Animals; Antiviral Agents; Benzylamines; CD4-CD8 Ratio; Chromatography, High Pressure Liquid; Cyclams; Didanosine; Drug Implants; Heterocyclic Compounds; HIV Infections; HIV-1; Injections, Subcutaneous; Mice; Mice, Inbred BALB C; Mice, SCID; Rats; Spectrophotometry, Ultraviolet; Virus Replication; Zidovudine

1996
Use of standardized SCID-hu Thy/Liv mouse model for preclinical efficacy testing of anti-human immunodeficiency virus type 1 compounds.
    Antimicrobial agents and chemotherapy, 1996, Volume: 40, Issue:3

    Topics: Animals; Antiviral Agents; Didanosine; DNA, Viral; Enzyme-Linked Immunosorbent Assay; Fetal Tissue Transplantation; Flow Cytometry; HIV Core Protein p24; HIV Infections; HIV-1; Humans; Liver Transplantation; Lymphocyte Count; Mice; Mice, SCID; Neutrophils; Nevirapine; Polymerase Chain Reaction; Pyridines; Rats; T-Lymphocytes; Thymus Gland; Transplantation, Heterologous; Zidovudine

1996
Intestinal absorption and first-pass elimination of 2', 3'-dideoxynucleosides following oral administration in rats.
    Biological & pharmaceutical bulletin, 1996, Volume: 19, Issue:4

    Topics: Administration, Oral; Animals; Anti-HIV Agents; Area Under Curve; Biological Availability; Didanosine; Dideoxynucleosides; Intestinal Absorption; Intestinal Mucosa; Male; Rats; Rats, Wistar; Stavudine; Zidovudine

1996
Inhibition of the in vitro infectivity and cytopathic effect of human foamy virus by dideoxynucleosides.
    AIDS research and human retroviruses, 1996, Oct-10, Volume: 12, Issue:15

    Topics: Blotting, Southern; Cytopathogenic Effect, Viral; Didanosine; Dideoxynucleosides; DNA, Viral; Humans; Microscopy, Electron; Spumavirus; Tumor Cells, Cultured; Zalcitabine; Zidovudine

1996
Increased plasma human immunodeficiency virus type 1 burden following antigenic challenge with pneumococcal vaccine.
    The Journal of infectious diseases, 1996, Volume: 174, Issue:6

    Topics: Adult; Anti-HIV Agents; Antibodies, Bacterial; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Didanosine; Disease Progression; DNA, Viral; HIV Infections; HIV-1; Humans; Immunoglobulin G; Influenza Vaccines; Lymphocyte Activation; Middle Aged; Pneumococcal Infections; Polysaccharides, Bacterial; Proviruses; Receptors, Interleukin-2; RNA, Viral; Time Factors; Vaccination; Vaccines; Viral Load; Zidovudine

1996
Efficacy of a combined zidovudine plus didanosine therapy in one case of HIV-related thrombocytopenia non-responder to zidovudine alone or to anti-Rho immunoglobulin administration.
    AIDS (London, England), 1996, Volume: 10, Issue:14

    Topics: Acute-Phase Proteins; Adult; Anti-HIV Agents; Didanosine; Drug Resistance; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Immunoglobulins, Intravenous; Male; Thrombocytopenia; Zidovudine

1996
[Nevirapine: a new principle of action against HIV].
    Deutsche medizinische Wochenschrift (1946), 1996, Dec-06, Volume: 121, Issue:49

    Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Child; Clinical Trials as Topic; Didanosine; Double-Blind Method; Drug Therapy, Combination; Female; HIV; HIV Infections; Humans; Infant, Newborn; Male; Nevirapine; Pregnancy; Pregnancy Complications, Infectious; Pyridines; Randomized Controlled Trials as Topic; Reverse Transcriptase Inhibitors; Time Factors; Zidovudine

1996
Stavudine selectively induces apoptosis in HIV type 1-infected cells.
    AIDS research and human retroviruses, 1997, Jan-20, Volume: 13, Issue:2

    Topics: Anti-HIV Agents; Apoptosis; Cell Line; Didanosine; DNA Fragmentation; Down-Regulation; HIV Reverse Transcriptase; HIV-1; Humans; Nevirapine; Proto-Oncogene Proteins c-bcl-2; Pyridines; Reverse Transcriptase Inhibitors; Stavudine; T-Lymphocytes; Thymidine; Zalcitabine; Zidovudine

1997
The Delta trial.
    Lancet (London, England), 1997, Feb-01, Volume: 349, Issue:9048

    Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Clinical Trials as Topic; Didanosine; Drug Therapy, Combination; HIV Infections; Humans; Zalcitabine; Zidovudine

1997
Focusing on the second phase of plasma HIV-1 RNA clearance.
    AIDS (London, England), 1997, Volume: 11, Issue:2

    Topics: Anti-HIV Agents; Didanosine; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Lamivudine; Reverse Transcriptase Inhibitors; RNA, Viral; Virus Replication; Zidovudine

1997
Treatment of late-state HIV infection.
    The Journal of family practice, 1997, Volume: 44, Issue:2

    Topics: Acquired Immunodeficiency Syndrome; Adolescent; Anti-HIV Agents; CD4 Lymphocyte Count; Didanosine; Disease Progression; Double-Blind Method; Drug Combinations; HIV Infections; Humans; Randomized Controlled Trials as Topic; Reproducibility of Results; Reverse Transcriptase Inhibitors; Treatment Outcome; Zalcitabine; Zidovudine

1997
Effect of antiretroviral combination therapy (zidovudine/didanosine or zidovudine/lamivudine) on quantitative plasma human immunodeficiency virus-ribonucleic acid in children and adolescents infected with human immunodeficiency virus.
    The Journal of pediatrics, 1997, Volume: 130, Issue:2

    Topics: Adolescent; AIDS-Related Opportunistic Infections; Anti-HIV Agents; CD4 Lymphocyte Count; Child; Child, Preschool; Didanosine; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Infant; Lamivudine; Male; RNA, Viral; Time Factors; Viral Load; Viremia; Zidovudine

1997
The impact of ethanol and Marinol/marijuana usage on HIV+/AIDS patients undergoing azidothymidine, azidothymidine/dideoxycytidine, or dideoxyinosine therapy.
    Alcoholism, clinical and experimental research, 1997, Volume: 21, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Adult; Aged; Alcohol Drinking; Amylases; Anti-HIV Agents; Appetite Stimulants; CD4 Lymphocyte Count; Didanosine; Dronabinol; Drug Therapy, Combination; Female; Follow-Up Studies; HIV Seropositivity; Humans; Liver Function Tests; Male; Marijuana Smoking; Middle Aged; Pancreatitis, Alcoholic; Zalcitabine; Zidovudine

1997
HIV-1 drug susceptibilities and reverse transcriptase mutations in patients receiving combination therapy with didanosine and delavirdine.
    Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association, 1997, Feb-01, Volume: 14, Issue:2

    Topics: Adult; Anti-HIV Agents; Delavirdine; Didanosine; Drug Resistance, Microbial; Drug Therapy, Combination; Female; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Indoles; Male; Mutation; Phenotype; Piperazines; Reverse Transcriptase Inhibitors; RNA, Viral; Viral Load; Zidovudine

1997
Resolution of HIV-associated cystic benign lymphoepithelial lesion of the parotid gland in a patient undergoing chemotherapy for non-Hodgkin's lymphoma.
    Scandinavian journal of infectious diseases, 1996, Volume: 28, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Antiviral Agents; Cyclophosphamide; Cysts; Didanosine; Doxorubicin; Fatal Outcome; HIV Infections; Humans; Hyperplasia; Lymphoma, Non-Hodgkin; Male; Middle Aged; Parotid Diseases; Prednisone; Vincristine; Zidovudine

1996
Effect of nucleoside analogs on neurite regeneration and mitochondrial DNA synthesis in PC-12 cells.
    The Journal of pharmacology and experimental therapeutics, 1997, Volume: 280, Issue:3

    Topics: Animals; Didanosine; Dideoxynucleosides; DNA Replication; DNA, Mitochondrial; Nerve Growth Factors; Neurites; PC12 Cells; Phosphorylation; Rats; Stavudine; Zalcitabine; Zidovudine

1997
Shedding of HIV-1 in semen during primary infection.
    AIDS (London, England), 1997, Mar-15, Volume: 11, Issue:4

    Topics: Anti-HIV Agents; Didanosine; Follow-Up Studies; HIV Infections; HIV-1; Humans; Male; RNA, Viral; Semen; Virus Shedding; Zidovudine

1997
Analysis of repeated virological measurements based on cell dilution assays.
    Statistics in medicine, 1997, Mar-15, Volume: 16, Issue:5

    Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Didanosine; Drug Therapy, Combination; HIV Infections; Humans; Models, Statistical; Survival Analysis; Treatment Outcome; Viral Load; Zidovudine

1997
In vivo evidence for carrier-mediated efflux transport of 3'-azido-3'-deoxythymidine and 2',3'-dideoxyinosine across the blood-brain barrier via a probenecid-sensitive transport system.
    The Journal of pharmacology and experimental therapeutics, 1997, Volume: 281, Issue:1

    Topics: Animals; Anti-HIV Agents; Biological Transport; Blood-Brain Barrier; Brain; Didanosine; Dose-Response Relationship, Drug; Inulin; Male; Probenecid; Rats; Rats, Wistar; Zidovudine

1997
Inhibition of human immunodeficiency virus type 1 infection in vitro by combination of delavirdine, zidovudine and didanosine.
    Antiviral research, 1997, Volume: 34, Issue:1

    Topics: Anti-HIV Agents; Cell Line; Delavirdine; Didanosine; DNA, Viral; HIV-1; Humans; Indoles; Piperazines; Polymerase Chain Reaction; Reverse Transcriptase Inhibitors; Zidovudine

1997
Hearing loss and antiretroviral therapy in patients infected with HIV-1.
    Archives of neurology, 1997, Volume: 54, Issue:4

    Topics: Adult; Anti-HIV Agents; Didanosine; Female; Hearing Disorders; HIV Infections; HIV-1; Humans; Male; Middle Aged; Stavudine; Zidovudine

1997
Pharmacokinetics of oral ganciclovir capsules in HIV-infected persons.
    AIDS (London, England), 1996, Volume: 10 Suppl 4

    Topics: Anti-HIV Agents; Antiviral Agents; Area Under Curve; Biological Availability; Clinical Trials as Topic; Didanosine; Drug Interactions; Drug Therapy, Combination; Ganciclovir; HIV Infections; Humans; Zidovudine

1996
Antiretroviral effect of zidovudine-didanosine combination on blood and lymph nodes.
    AIDS (London, England), 1997, Volume: 11, Issue:1

    Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Didanosine; DNA, Viral; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Leukocytes, Mononuclear; Lymph Nodes; Male; Viral Load; Zidovudine

1997
HIV-associated primary pulmonary hypertension. A case control study. Swiss HIV Cohort Study.
    American journal of respiratory and critical care medicine, 1997, Volume: 155, Issue:3

    Topics: Adult; Anti-HIV Agents; Antibodies, Anticardiolipin; Case-Control Studies; Didanosine; Echocardiography, Doppler; Enzyme-Linked Immunosorbent Assay; Female; HIV Infections; Humans; Hypertension, Pulmonary; Immunoglobulin M; Male; Prospective Studies; Survival Rate; Zidovudine

1997
2.5 year remission of AIDS-associated progressive multifocal leukoencephalopathy with combined antiretroviral therapy.
    Lancet (London, England), 1997, Mar-22, Volume: 349, Issue:9055

    Topics: Adult; AIDS-Related Opportunistic Infections; Anti-HIV Agents; CD4 Lymphocyte Count; Didanosine; Drug Therapy, Combination; HIV Protease Inhibitors; Humans; Indinavir; Leukoencephalopathy, Progressive Multifocal; Male; Time Factors; Zidovudine

1997
Treatment options for human immunodeficiency virus.
    South Dakota journal of medicine, 1996, Volume: 49, Issue:2

    Topics: Acquired Immunodeficiency Syndrome; Adult; Antiviral Agents; Child; Didanosine; Drug Approval; Female; HIV Infections; HIV Protease Inhibitors; Humans; Infant, Newborn; Lamivudine; Male; Saquinavir; Stavudine; United States; United States Food and Drug Administration; Zalcitabine; Zidovudine

1996
Genotypic and phenotypic changes during culture of a multinucleoside-resistant human immunodeficiency virus type 1 strain in the presence and absence of additional reverse transcriptase inhibitors.
    Antimicrobial agents and chemotherapy, 1996, Volume: 40, Issue:12

    Topics: Antiviral Agents; Cell Line; Cells, Cultured; Didanosine; Drug Interactions; Drug Resistance, Microbial; Drug Resistance, Multiple; Genotype; HIV-1; Humans; Lamivudine; Mutation; Nevirapine; Pyridines; Reverse Transcriptase Inhibitors; Virus Replication; Zidovudine

1996
[Therapeutic strategies against HIV: status in 1994 and future prospectives].
    Der Internist, 1994, Volume: 35, Issue:7 Suppl

    Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Clinical Trials as Topic; Didanosine; Forecasting; HIV Infections; Humans; Male; Zalcitabine; Zidovudine

1994
Phenotypic variations and switches in HIV isolated from the blood and the gastrointestinal tissues of patients with HIV-1 infection. HIV/GI Research Study Group.
    Journal of medical virology, 1997, Volume: 52, Issue:1

    Topics: Biopsy; Didanosine; Digestive System; Female; Giant Cells; HIV; HIV Enteropathy; HIV Infections; Humans; Male; Mutation; Phenotype; Prospective Studies; Stavudine; Viral Load; Zidovudine

1997
Determination of HIV-1 susceptibility to reverse transcriptase (RT) inhibitors by a quantitative cell-free RT assay.
    Clinical and diagnostic virology, 1996, Volume: 7, Issue:2

    Topics: Cell-Free System; Didanosine; Drug Resistance; HIV Reverse Transcriptase; HIV-1; Humans; Reproducibility of Results; Reverse Transcriptase Inhibitors; Sensitivity and Specificity; Zidovudine

1996
Use of the Wei-Lin-Weissfeld method for the analysis of a recurring and a terminating event.
    Statistics in medicine, 1997, Apr-30, Volume: 16, Issue:8

    Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Didanosine; Drug Therapy, Combination; HIV-1; Humans; Models, Statistical; Proportional Hazards Models; Randomized Controlled Trials as Topic; Recurrence; Time Factors; Zidovudine

1997
Cellular and mitochondrial toxicity of zidovudine (AZT), didanosine (ddI) and zalcitabine (ddC) on cultured human muscle cells.
    Journal of the neurological sciences, 1997, Volume: 149, Issue:1

    Topics: Anti-HIV Agents; Biopsy; Cell Differentiation; Cell Division; Cells, Cultured; Didanosine; DNA, Mitochondrial; Dose-Response Relationship, Drug; Electron Transport Complex II; Electron Transport Complex IV; Humans; Kinetics; Lactates; Lipid Metabolism; Mitochondria, Muscle; Multienzyme Complexes; Muscle, Skeletal; NAD(P)H Dehydrogenase (Quinone); Nucleic Acid Synthesis Inhibitors; Oxidoreductases; Succinate Dehydrogenase; Zalcitabine; Zidovudine

1997
Correlation between plasma HIV-1 RNA levels and the rate of immunologic decline.
    Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association, 1997, Apr-15, Volume: 14, Issue:5

    Topics: Anti-HIV Agents; beta 2-Microglobulin; CD4 Lymphocyte Count; Didanosine; Disease Progression; DNA, Viral; Drug Therapy, Combination; HIV Core Protein p24; HIV Infections; HIV-1; Humans; Longitudinal Studies; RNA, Viral; Stavudine; Viral Load; Viremia; Virus Replication; Zalcitabine; Zidovudine

1997
Sequence and drug susceptibility of subtype C reverse transcriptase from human immunodeficiency virus type 1 seroconverters in Zimbabwe.
    Journal of virology, 1997, Volume: 71, Issue:7

    Topics: Adult; Amino Acid Sequence; Base Sequence; Didanosine; DNA, Viral; Female; Genes, env; HIV Reverse Transcriptase; HIV Seropositivity; HIV-1; Humans; Lamivudine; Male; Middle Aged; Molecular Sequence Data; Nevirapine; Nucleic Acid Heteroduplexes; Phylogeny; Pyridines; Reverse Transcriptase Inhibitors; Sequence Homology, Amino Acid; Zidovudine; Zimbabwe

1997
Quantification of HIV-1 viral load in lymphoid and blood cells: assessment during four-drug combination therapy.
    AIDS (London, England), 1997, Volume: 11, Issue:7

    Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Didanosine; DNA, Viral; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Lamivudine; Leukocytes, Mononuclear; Lymph Nodes; Male; Polymerase Chain Reaction; RNA, Viral; Saquinavir; Viral Load; Viremia; Zidovudine

1997
Stable neurological function in subjects treated with 2'3'-dideoxyinosine.
    Journal of neurovirology, 1997, Volume: 3, Issue:3

    Topics: Adult; AIDS Dementia Complex; Anti-HIV Agents; CD4 Lymphocyte Count; Didanosine; Follow-Up Studies; HIV Infections; Humans; Neuropsychological Tests; Zidovudine

1997
The effect on human immunodeficiency virus type 1 RNA levels in cerebrospinal fluid after initiation of zidovudine or didanosine.
    The Journal of infectious diseases, 1997, Volume: 175, Issue:2

    Topics: Adult; Aged; Anti-HIV Agents; beta 2-Microglobulin; Biopterins; Didanosine; HIV Infections; HIV-1; Humans; Middle Aged; Neopterin; RNA, Viral; Viral Load; Zidovudine

1997
Successful treatment of HIV-1-related, zidovudine resistant, thrombocytopenia with didanosine.
    American journal of hematology, 1997, Volume: 55, Issue:2

    Topics: Adult; CD4 Lymphocyte Count; Didanosine; HIV Infections; Humans; Male; Platelet Count; Thrombocytopenia; Zidovudine

1997
Downregulation of increased CD95 (APO-1/Fas) ligand in T cells from human immunodeficiency virus-type 1-infected children after antiretroviral therapy.
    Blood, 1997, Jul-15, Volume: 90, Issue:2

    Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Child; Didanosine; Drug Therapy, Combination; Fas Ligand Protein; fas Receptor; Gene Expression Regulation; HIV Infections; HIV-1; Humans; Lamivudine; Membrane Glycoproteins; Reverse Transcriptase Inhibitors; RNA, Messenger; T-Lymphocytes; Time Factors; Transcription, Genetic; Zalcitabine; Zidovudine

1997
Cure or control of HIV/AIDS?
    Medical hypotheses, 1997, Volume: 48, Issue:6

    Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Didanosine; Drug Resistance, Microbial; Drug Therapy, Combination; HIV; HIV Infections; Humans; Indinavir; Lamivudine; Models, Biological; Nevirapine; Pyridines; Ritonavir; Saquinavir; Stavudine; Zalcitabine; Zidovudine

1997
Monitoring antiretroviral activity using ICDp24 and CD4 counts in HIV infection.
    The Journal of infection, 1997, Volume: 35, Issue:1

    Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Didanosine; Follow-Up Studies; HIV Core Protein p24; HIV Infections; Humans; Zidovudine

1997
[Anti-retrovirals].
    Medicina clinica, 1997, Jun-07, Volume: 109, Issue:2

    Topics: Anti-HIV Agents; Didanosine; Reverse Transcriptase Inhibitors; Stavudine; Zalcitabine; Zidovudine

1997
Human immunodeficiency virus type 1 dynamics in different lymphoid tissue compartments.
    The Journal of infectious diseases, 1997, Volume: 176, Issue:3

    Topics: Adult; Anti-HIV Agents; Didanosine; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Lamivudine; Leukocytes, Mononuclear; Lymphoid Tissue; Male; RNA, Viral; Zidovudine

1997
[Once-daily administration of didanosine in combination with anti-retroviral zidovudine in previously untreated patients].
    Pathologie-biologie, 1997, Volume: 45, Issue:5

    Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; Didanosine; Drug Therapy, Combination; Female; HIV; HIV Infections; Humans; Male; Middle Aged; RNA, Viral; Zidovudine

1997
Distributed model analysis of 3'-azido-3'-deoxythymidine and 2',3'-dideoxyinosine distribution in brain tissue and cerebrospinal fluid.
    The Journal of pharmacology and experimental therapeutics, 1997, Volume: 282, Issue:3

    Topics: Animals; Anti-HIV Agents; Blood-Brain Barrier; Brain; Didanosine; Male; Models, Biological; Rats; Rats, Wistar; Zidovudine

1997
Transport properties of 3'-azido-3'-deoxythymidine and 2',3'-dideoxyinosine in the rat choroid plexus.
    Biopharmaceutics & drug disposition, 1997, Volume: 18, Issue:7

    Topics: 4-Chloromercuribenzenesulfonate; Animals; Anti-HIV Agents; Biological Transport, Active; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Chloromercuribenzoates; Choroid Plexus; Didanosine; Dose-Response Relationship, Drug; In Vitro Techniques; Male; p-Chloromercuribenzoic Acid; Penicillin G; Rats; Rats, Wistar; Rotenone; Sulfhydryl Reagents; Tritium; Uncoupling Agents; Zidovudine

1997
Transient renewal of thymopoiesis in HIV-infected human thymic implants following antiviral therapy.
    Nature medicine, 1997, Volume: 3, Issue:10

    Topics: Animals; Antigens, CD; Antigens, CD34; Antiviral Agents; CD4-Positive T-Lymphocytes; Didanosine; Drug Therapy, Combination; Flow Cytometry; Hematopoietic Stem Cells; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Lymphocyte Depletion; Methylurea Compounds; Mice; Mice, SCID; Polymerase Chain Reaction; Proviruses; Pyridines; T-Lymphocytes; Thymus Gland; Transplantation, Heterologous; Valine; Zidovudine

1997
Lamivudine (3TC) phosphorylation and drug interactions in vitro.
    Biochemical pharmacology, 1997, Sep-01, Volume: 54, Issue:5

    Topics: Anti-HIV Agents; Cells, Cultured; Deoxycytidine; Didanosine; Dideoxynucleosides; Drug Interactions; Humans; Kinetics; Lamivudine; Lymphocyte Activation; Lymphocytes; Mitogens; Models, Chemical; Monocytes; Phosphorylation; Stavudine; Tumor Cells, Cultured; Zalcitabine; Zidovudine

1997
Comparative metabolism of the antiviral dimer 3'-azido-3'-deoxythymidine-P-2',3'-dideoxyinosine and the monomers zidovudine and didanosine by rat, monkey, and human hepatocytes.
    Antimicrobial agents and chemotherapy, 1997, Volume: 41, Issue:11

    Topics: Animals; Anti-HIV Agents; Cell Survival; Cells, Cultured; Didanosine; Dideoxynucleotides; Haplorhini; Humans; Liver; Rats; Rats, Sprague-Dawley; Species Specificity; Zidovudine

1997
[Initial administration of a protease inhibitor delays the progression of AIDS by half time].
    Deutsche medizinische Wochenschrift (1946), 1997, Oct-17, Volume: 122, Issue:42

    Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Didanosine; Disease Progression; HIV Infections; HIV Protease Inhibitors; Humans; Time Factors; Zalcitabine; Zidovudine

1997
Human immunodeficiency virus infection impairs hemopoiesis in long-term bone marrow cultures: nonreversal by nucleoside analogues.
    The Journal of infectious diseases, 1997, Volume: 176, Issue:6

    Topics: Anti-HIV Agents; Antigens, CD34; Apoptosis; Bone Marrow Cells; Cell Death; Cells, Cultured; Didanosine; Hematopoiesis; Hematopoietic Stem Cells; HIV; HIV Core Protein p24; Humans; Stromal Cells; Zidovudine

1997
Drugs for HIV infection.
    The Medical letter on drugs and therapeutics, 1997, Dec-12, Volume: 39, Issue:1015

    Topics: AIDS-Related Opportunistic Infections; Anti-HIV Agents; Delavirdine; Diarrhea; Didanosine; Drug Interactions; Drug Therapy, Combination; HIV Infections; Humans; Indinavir; Lamivudine; Nelfinavir; Nevirapine; Protease Inhibitors; Reverse Transcriptase Inhibitors; Ritonavir; Saquinavir; Virus Replication; Zalcitabine; Zidovudine

1997
Selective inhibition of syncytium-inducing and nonsyncytium-inducing HIV-1 variants in individuals receiving didanosine or zidovudine, respectively.
    The Journal of clinical investigation, 1997, Nov-01, Volume: 100, Issue:9

    Topics: Animals; Anti-HIV Agents; CD4 Lymphocyte Count; Cell Fusion; Didanosine; Giant Cells; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Mice; Ritonavir; RNA, Viral; Zidovudine

1997
Antiretroviral therapy and HIV-related retinal microangiopathy.
    AIDS (London, England), 1997, Volume: 11, Issue:15

    Topics: Adult; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Didanosine; Female; Humans; Male; Middle Aged; Retinal Diseases; Retinal Vessels; Reverse Transcriptase Inhibitors; Zidovudine

1997
Drug susceptibility of subtypes A,B,C,D, and E human immunodeficiency virus type 1 primary isolates.
    AIDS research and human retroviruses, 1998, Jan-20, Volume: 14, Issue:2

    Topics: Anti-HIV Agents; Cell Line, Transformed; Cells, Cultured; Didanosine; Foscarnet; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Leukocytes, Mononuclear; Nevirapine; Reverse Transcriptase Inhibitors; Ritonavir; Zidovudine

1998
Oligonucleotide ligation assay for detecting mutations in the human immunodeficiency virus type 1 pol gene that are associated with resistance to zidovudine, didanosine, and lamivudine.
    Journal of clinical microbiology, 1998, Volume: 36, Issue:2

    Topics: Anti-HIV Agents; Codon; Didanosine; Drug Resistance, Microbial; Genes, pol; HIV Infections; HIV-1; Humans; Lamivudine; Mutation; Oligonucleotide Probes; Polymerase Chain Reaction; RNA, Viral; Sensitivity and Specificity; Sequence Analysis, DNA; Zidovudine

1998
Effect of combined zidovudine and didanosine therapy in early asymptomatic primary HIV-1 infection.
    AIDS (London, England), 1998, Jan-22, Volume: 12, Issue:2

    Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Didanosine; Drug Therapy, Combination; HIV Core Protein p24; HIV Infections; HIV-1; Humans; Polymerase Chain Reaction; Treatment Outcome; Zidovudine

1998
Changes in CD8 cell subpopulations induced by antiretroviral therapy in human immunodeficiency virus infected patients.
    Viral immunology, 1997, Volume: 10, Issue:4

    Topics: Adult; Anti-HIV Agents; CD8-Positive T-Lymphocytes; Cell Count; Didanosine; Drug Therapy, Combination; Flow Cytometry; HIV Seropositivity; HIV-1; Humans; Male; Phenotype; RNA, Viral; Viremia; Zidovudine

1997
HIV-1 acquires resistance to two classes of antiviral drugs through homologous recombination.
    Antiviral research, 1997, Volume: 36, Issue:3

    Topics: Animals; Anti-HIV Agents; Cell Line, Transformed; COS Cells; Didanosine; Drug Resistance, Microbial; Drug Resistance, Multiple; HIV Protease; HIV Protease Inhibitors; HIV Reverse Transcriptase; HIV-1; Humans; Mutagenesis; Oligopeptides; Polymerase Chain Reaction; Recombination, Genetic; Reverse Transcriptase Inhibitors; Transfection; Virus Replication; Zalcitabine; Zidovudine

1997
Effect of protease inhibitors on nucleoside analogue phosphorylation in vitro.
    British journal of clinical pharmacology, 1998, Volume: 45, Issue:2

    Topics: Anti-HIV Agents; Cell Count; Cell Survival; Didanosine; Drug Interactions; Humans; Indinavir; Lamivudine; Leukocytes, Mononuclear; Nucleosides; Phosphorylation; Protease Inhibitors; Ritonavir; Saquinavir; Stavudine; Trypan Blue; Tumor Cells, Cultured; Zalcitabine; Zidovudine

1998
Survival in 2367 zidovudine-treated patients according to use of other nucleoside analogue drugs. The EuroSIDA Study Group.
    Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association, 1998, Mar-01, Volume: 17, Issue:3

    Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Cohort Studies; Didanosine; Dideoxynucleosides; Disease Progression; Drug Therapy, Combination; Europe; Female; Follow-Up Studies; HIV Infections; Humans; Lamivudine; Male; Middle Aged; Proportional Hazards Models; Prospective Studies; Stavudine; Survival Analysis; Zalcitabine; Zidovudine

1998
Visceral leishmaniasis in patients infected with the human immunodeficiency virus.
    European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 1997, Volume: 16, Issue:12

    Topics: AIDS-Related Opportunistic Infections; Allopurinol; Amebicides; Amphotericin B; Analysis of Variance; Anti-HIV Agents; Antimetabolites; Antimony; Antiprotozoal Agents; Blood; Bone Marrow; CD4-Positive T-Lymphocytes; Cerebrospinal Fluid; Didanosine; Digestive System; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Follow-Up Studies; Hepatic Encephalopathy; HIV; Humans; Intestinal Mucosa; Leishmaniasis, Visceral; Lymphocyte Count; Male; Myocarditis; Neutrophils; Pancreatitis; Pentamidine; Renal Insufficiency; Spain; Zidovudine

1997
Brain lactate and N-acetylaspartate in pediatric AIDS encephalopathy.
    AJNR. American journal of neuroradiology, 1998, Volume: 19, Issue:2

    Topics: AIDS Dementia Complex; Anti-HIV Agents; Aspartic Acid; Brain; Child; Child, Preschool; Creatine; Didanosine; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Lactic Acid; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Neurologic Examination; Zidovudine

1998
Combination therapy for HIV: the effect on inpatient activity, morbidity and mortality of a cohort of patients.
    International journal of STD & AIDS, 1998, Volume: 9, Issue:2

    Topics: Anti-HIV Agents; Cohort Studies; Cost Savings; Costs and Cost Analysis; Didanosine; Drug Therapy, Combination; Follow-Up Studies; HIV Infections; Humans; Prospective Studies; Zalcitabine; Zidovudine

1998
1,1,3-Trioxo-2H,4H-thieno[3,4-e][1,2,4]thiadiazine (TTD) derivatives: a new class of nonnucleoside human immunodeficiency virus type 1 (HIV-1) reverse transcriptase inhibitors with anti-HIV-1 activity.
    Antimicrobial agents and chemotherapy, 1998, Volume: 42, Issue:3

    Topics: Anti-HIV Agents; Cells, Cultured; Didanosine; Drug Resistance, Microbial; HIV Reverse Transcriptase; HIV-1; Humans; Models, Molecular; Nevirapine; Structure-Activity Relationship; Zidovudine

1998
Resolution of Mycobacterium avium complex bacteremia following highly active antiretroviral therapy.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1998, Volume: 26, Issue:3

    Topics: Adult; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Bacteremia; Didanosine; Drug Therapy, Combination; HIV Protease Inhibitors; Humans; Indinavir; Male; Mycobacterium avium-intracellulare Infection; Reverse Transcriptase Inhibitors; Zidovudine

1998
[Combined antiretroviral therapy for prevention of vertical HIV-1 transmission].
    Anales de medicina interna (Madrid, Spain : 1984), 1998, Volume: 15, Issue:3

    Topics: Adult; Anti-HIV Agents; Didanosine; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Infectious Disease Transmission, Vertical; Pregnancy; Pregnancy Complications, Infectious; Zidovudine

1998
Altered drug sensitivity, fitness, and evolution of human immunodeficiency virus type 1 with pol gene mutations conferring multi-dideoxynucleoside resistance.
    The Journal of infectious diseases, 1998, Volume: 177, Issue:5

    Topics: Animals; Anti-HIV Agents; Cells, Cultured; COS Cells; Didanosine; Dideoxynucleosides; Drug Resistance, Microbial; Drug Resistance, Multiple; Evolution, Molecular; Genes, pol; HIV-1; Humans; Lymphocytes; Microbial Sensitivity Tests; Mutation; Virus Replication; Zalcitabine; Zidovudine

1998
Virus burden in lymph nodes and blood of subjects with primary human immunodeficiency virus type 1 infection on bitherapy.
    The Journal of infectious diseases, 1998, Volume: 177, Issue:6

    Topics: Adenoids; Adult; Anti-HIV Agents; CD4-CD8 Ratio; Dendritic Cells; Didanosine; DNA, Viral; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Lymph Nodes; Male; Middle Aged; Palatine Tonsil; Proviruses; Reverse Transcriptase Inhibitors; Viral Load; Virus Replication; Zidovudine

1998
Emergence of multi-dideoxynucleoside-resistant human immunodeficiency virus type 1 variants, viral sequence variation, and disease progression in patients receiving antiretroviral chemotherapy.
    The Journal of infectious diseases, 1998, Volume: 177, Issue:6

    Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Child; Didanosine; Dideoxynucleosides; Disease Progression; Drug Resistance, Microbial; Drug Resistance, Multiple; Drug Therapy, Combination; Genetic Variation; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Point Mutation; Reverse Transcriptase Inhibitors; RNA, Viral; Zalcitabine; Zidovudine

1998
Human immunodeficiency virus proviral DNA from peripheral blood and lymph nodes demonstrates concordant resistance mutations to zidovudine (codon 215) and didanosine (codon 74). Division of AIDS Treatment Research Initiative 003 Study Group.
    The Journal of infectious diseases, 1998, Volume: 177, Issue:6

    Topics: Adult; Anti-HIV Agents; Codon; Didanosine; DNA, Viral; Drug Resistance, Microbial; Drug Resistance, Multiple; Female; HIV Infections; HIV-1; Humans; Leukocytes, Mononuclear; Lymph Nodes; Male; Point Mutation; Proviruses; Reverse Transcriptase Inhibitors; Zidovudine

1998
Induction-maintenance antiretroviral therapy: proof of concept.
    AIDS (London, England), 1998, May-07, Volume: 12, Issue:7

    Topics: Anti-HIV Agents; Didanosine; Drug Therapy, Combination; Follow-Up Studies; HIV Infections; Humans; Nevirapine; Reverse Transcriptase Inhibitors; Viral Load; Zidovudine

1998
Clinical and biological impact of antiretroviral therapy with protease inhibitors on HIV-related Kaposi's sarcoma.
    AIDS (London, England), 1998, May-07, Volume: 12, Issue:7

    Topics: Adult; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Didanosine; Dideoxynucleosides; Drug Therapy, Combination; Female; Herpesvirus 8, Human; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Male; Middle Aged; Prospective Studies; Reverse Transcriptase Inhibitors; Ritonavir; Saquinavir; Sarcoma, Kaposi; Stavudine; Treatment Outcome; Viral Load; Viremia; Zalcitabine; Zidovudine

1998
The M184V mutation in HIV-1 reverse transcriptase (RT) conferring lamivudine resistance does not result in broad cross-resistance to nucleoside analogue RT inhibitors.
    AIDS (London, England), 1998, May-07, Volume: 12, Issue:7

    Topics: Anti-HIV Agents; Cohort Studies; Didanosine; Dideoxynucleosides; Drug Resistance, Microbial; Drug Resistance, Multiple; Drug Therapy, Combination; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Methionine; Point Mutation; Reverse Transcriptase Inhibitors; Stavudine; Valine; Zalcitabine; Zidovudine

1998
Researchers report sustained suppression of HIV with nevirapine--didanosine--zidovudine.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 1998, Jun-01, Volume: 55, Issue:11

    Topics: Anti-HIV Agents; Didanosine; Drug Therapy, Combination; HIV Infections; Humans; Nevirapine; Reverse Transcriptase Inhibitors; Zidovudine

1998
A mixed model for repeated dilution assays.
    Biometrics, 1998, Volume: 54, Issue:2

    Topics: Anti-HIV Agents; Didanosine; Drug Therapy, Combination; HIV; HIV Infections; Humans; Models, Statistical; Multicenter Studies as Topic; Randomized Controlled Trials as Topic; Reproducibility of Results; Viral Load; Zalcitabine; Zidovudine

1998
Metabolism of 2',3'-dideoxy-2',3'-didehydro-beta-L(-)-5-fluorocytidine and its activity in combination with clinically approved anti-human immunodeficiency virus beta-D(+) nucleoside analogs in vitro.
    Antimicrobial agents and chemotherapy, 1998, Volume: 42, Issue:7

    Topics: Anti-HIV Agents; Cell Line; Deamination; Deoxycytidine Kinase; Didanosine; DNA Polymerase gamma; DNA-Directed DNA Polymerase; DNA, Mitochondrial; DNA, Viral; Drug Interactions; HIV Reverse Transcriptase; HIV-1; Phosphorylation; Stavudine; Virus Replication; Zalcitabine; Zidovudine

1998
Prevalence of genotypic resistance to nucleoside analogues in antiretroviral-naive and antiretroviral-experienced HIV-infected patients in Spain.
    AIDS (London, England), 1998, Jun-18, Volume: 12, Issue:9

    Topics: Adult; Anti-HIV Agents; Cross-Sectional Studies; Didanosine; Dideoxynucleosides; Drug Resistance, Microbial; Female; Genotype; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Male; Prevalence; Reverse Transcriptase Inhibitors; Spain; Zalcitabine; Zidovudine

1998
Therapeutic advantage of hydroxyurea and didanosine combination therapy in patients previously treated with zidovudine.
    AIDS (London, England), 1998, Jun-18, Volume: 12, Issue:9

    Topics: Anti-HIV Agents; Didanosine; Drug Therapy, Combination; HIV Infections; Humans; Hydroxyurea; Retrospective Studies; Reverse Transcriptase Inhibitors; Zidovudine

1998
Risk of HIV dementia and opportunistic brain disease in AIDS and zidovudine therapy.
    Journal of neurology, neurosurgery, and psychiatry, 1998, Volume: 65, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Adult; AIDS Dementia Complex; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Brain Diseases; Didanosine; Female; Follow-Up Studies; Humans; Longitudinal Studies; Male; Retrospective Studies; Risk; Stavudine; Treatment Outcome; Zalcitabine; Zidovudine

1998
Therapeutic and other interventions to reduce the risk of mother-to-child transmission of HIV-1 in Europe. The European Collaborative Study.
    British journal of obstetrics and gynaecology, 1998, Volume: 105, Issue:7

    Topics: Adult; Anti-HIV Agents; Breast Feeding; Cesarean Section; Cohort Studies; Didanosine; Europe; Female; HIV Infections; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Pregnancy; Pregnancy Complications, Infectious; Prenatal Care; Prospective Studies; Risk Factors; Zidovudine

1998
Comparison of the LiPA HIV-1 RT test, selective PCR and direct solid phase sequencing for the detection of HIV-1 drug resistance mutations.
    Journal of virological methods, 1998, Volume: 73, Issue:1

    Topics: Anti-HIV Agents; Codon; Didanosine; DNA Probes; Drug Resistance, Microbial; Drug Therapy, Combination; Genotype; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Mutation; Polymerase Chain Reaction; Sequence Analysis, DNA; Zalcitabine; Zidovudine

1998
Analysis of antiretroviral nucleosides by electrospray ionization mass spectrometry and collision induced dissociation.
    Nucleosides & nucleotides, 1998, Volume: 17, Issue:5

    Topics: Anti-HIV Agents; Didanosine; Dideoxynucleosides; Gas Chromatography-Mass Spectrometry; Lamivudine; Models, Chemical; Reverse Transcriptase Inhibitors; Spectrometry, Mass, Secondary Ion; Zalcitabine; Zidovudine

1998
Changes in blood CD8+ lymphocyte activation status and plasma HIV RNA levels during antiretroviral therapy.
    AIDS (London, England), 1998, Jul-30, Volume: 12, Issue:11

    Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; CD8-Positive T-Lymphocytes; Didanosine; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Immunophenotyping; Lymphocyte Activation; Male; Middle Aged; Prospective Studies; Reverse Transcriptase Inhibitors; RNA, Viral; Viral Load; Zidovudine

1998
Rebound of plasma HIV viral load following prolonged suppression with combination therapy.
    AIDS (London, England), 1998, Jul-30, Volume: 12, Issue:11

    Topics: Adult; Anti-HIV Agents; Didanosine; Drug Therapy, Combination; HIV Infections; Humans; Male; Nevirapine; Reverse Transcriptase Inhibitors; Time Factors; Viral Load; Zidovudine

1998
Visceral leishmaniasis: a lingual presentation in a patient with HIV infection.
    Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics, 1998, Volume: 86, Issue:2

    Topics: Adult; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Antimony; Antiprotozoal Agents; Didanosine; HIV Infections; Humans; Laryngitis; Leishmaniasis, Visceral; Male; Meglumine; Meglumine Antimoniate; Organometallic Compounds; Spain; Tongue Diseases; Zidovudine

1998
A semiparametric Bayesian approach to the random effects model.
    Biometrics, 1998, Volume: 54, Issue:3

    Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Bayes Theorem; Biometry; CD4 Lymphocyte Count; Clinical Trials as Topic; Didanosine; Longitudinal Studies; Models, Statistical; Randomized Controlled Trials as Topic; Zidovudine

1998
The sequential occurrence of pol 215 and pol 41 zidovudine resistance mutations is associated in an additive fashion with low CD4 cell counts and high plasma and cellular HIV viral load.
    Antiviral research, 1998, Volume: 39, Issue:1

    Topics: Adult; Anti-HIV Agents; Biomarkers; CD4 Lymphocyte Count; Cross-Sectional Studies; Didanosine; Drug Resistance, Microbial; Drug Therapy, Combination; Female; Genotype; HIV Infections; HIV-1; Humans; Longitudinal Studies; Male; Mutation; RNA, Viral; Viral Load; Zalcitabine; Zidovudine

1998
[Infection with Mycobacterium genavense in 2 HIV-seropositive patients in Amsterdam].
    Nederlands tijdschrift voor geneeskunde, 1998, Jul-11, Volume: 142, Issue:28

    Topics: Acquired Immunodeficiency Syndrome; Adult; AIDS-Related Opportunistic Infections; Anti-HIV Agents; CD4 Lymphocyte Count; Didanosine; Humans; Male; Mycobacterium Infections; Zidovudine

1998
Taste and smell complaints in HIV-infected patients.
    AIDS (London, England), 1998, Sep-10, Volume: 12, Issue:13

    Topics: Adult; Aged; Anti-Bacterial Agents; Anti-HIV Agents; Anti-Infective Agents; Clarithromycin; Didanosine; Female; HIV Infections; Humans; Indinavir; Lamivudine; Male; Middle Aged; Quality of Life; Ritonavir; Smell; Surveys and Questionnaires; Taste; Trimethoprim, Sulfamethoxazole Drug Combination; Zidovudine

1998
[Weak antiviral effect of changing two nucleoside analogues combined with antiretroviral agents. 3TC and d4T after ZDU and ddi or ddc].
    Presse medicale (Paris, France : 1983), 1998, Feb-28, Volume: 27, Issue:8

    Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Didanosine; Drug Therapy, Combination; Female; HIV Seropositivity; HIV-1; Humans; Lamivudine; Male; Retrospective Studies; Stavudine; Viral Load; Zalcitabine; Zidovudine

1998
Resting energy expenditure and body composition in children with HIV infection.
    Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association, 1998, Oct-01, Volume: 19, Issue:2

    Topics: Adipose Tissue; Anthropometry; Anti-HIV Agents; Arm; Body Composition; Body Water; Child; Child Development; Child, Preschool; Didanosine; Energy Intake; Energy Metabolism; Female; Growth Disorders; HIV Infections; Humans; Male; Muscle Development; Muscle, Skeletal; Skinfold Thickness; Zidovudine

1998
Advanced testicular germ cell tumor in a hemophilic patient with human immunodeficiency virus infection.
    Japanese journal of clinical oncology, 1998, Volume: 28, Issue:9

    Topics: Acquired Immunodeficiency Syndrome; Adult; Antineoplastic Combined Chemotherapy Protocols; Antiviral Agents; CD4 Lymphocyte Count; Cisplatin; Combined Modality Therapy; Didanosine; Drug Therapy, Combination; Etoposide; Factor VIII; Germinoma; Hemophilia A; Humans; Male; Orchiectomy; Saquinavir; Testicular Neoplasms; Zidovudine

1998
High incidence of nevirapine-associated rash in HIV-infected Chinese.
    AIDS (London, England), 1998, Oct-22, Volume: 12, Issue:15

    Topics: Anti-HIV Agents; CD4 Lymphocyte Count; China; Didanosine; Drug Eruptions; Drug Therapy, Combination; HIV Infections; Humans; Nevirapine; Reverse Transcriptase Inhibitors; Stavudine; Zidovudine

1998
A 6-basepair insert in the reverse transcriptase gene of human immunodeficiency virus type 1 confers resistance to multiple nucleoside inhibitors.
    The Journal of clinical investigation, 1998, Nov-15, Volume: 102, Issue:10

    Topics: Amino Acid Sequence; Anti-HIV Agents; Base Sequence; Cells, Cultured; Didanosine; Drug Resistance, Multiple; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Mutagenesis, Site-Directed; Mutation; Nucleosides; Reverse Transcriptase Inhibitors; Zalcitabine; Zidovudine

1998
Estimates of the virological benefit of antiretroviral therapy are both assay- and analysis-dependent.
    AIDS (London, England), 1998, Nov-12, Volume: 12, Issue:16

    Topics: Analysis of Variance; Anti-HIV Agents; Data Interpretation, Statistical; Didanosine; HIV Infections; HIV-1; Humans; Nevirapine; RNA, Viral; Statistics, Nonparametric; Time Factors; Viral Load; Zidovudine

1998
Zidovudine toxicity in uninfected healthcare workers. Italian Registry of Antiretroviral Prophylaxis.
    The American journal of medicine, 1997, May-19, Volume: 102, Issue:5B

    Topics: Anti-HIV Agents; Didanosine; Drug Therapy, Combination; Health Personnel; HIV Infections; Humans; Italy; Occupational Exposure; Registries; Retrospective Studies; Reverse Transcriptase Inhibitors; Zalcitabine; Zidovudine

1997
[Observing in HIV infections].
    Presse medicale (Paris, France : 1983), 1998, Nov-14, Volume: 27, Issue:35

    Topics: Anti-HIV Agents; Didanosine; Drug Therapy, Combination; HIV Infections; Humans; Patient Compliance; Physician-Patient Relations; Reverse Transcriptase Inhibitors; Time Factors; Zidovudine

1998
Nevirapine, didanosine, and zidovudine for patients with HIV: the INCAS trial. Italy, Netherlands, Canada, and Australia.
    JAMA, 1999, Jan-13, Volume: 281, Issue:2

    Topics: Anti-HIV Agents; Didanosine; Drug Therapy, Combination; HIV Infections; Humans; Nevirapine; Randomized Controlled Trials as Topic; Zidovudine

1999
Nevirapine, didanosine, and zidovudine for patients with HIV: the INCAS trial. Italy, Netherlands, Canada, and Australia.
    JAMA, 1999, Jan-13, Volume: 281, Issue:2

    Topics: Anti-HIV Agents; Didanosine; Drug Therapy, Combination; HIV Infections; Humans; Nevirapine; Randomized Controlled Trials as Topic; Viral Load; Zidovudine

1999
Normal T-cell telomerase activity and upregulation in human immunodeficiency virus-1 infection.
    Blood, 1999, Feb-01, Volume: 93, Issue:3

    Topics: Anti-HIV Agents; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cohort Studies; Didanosine; Drug Therapy, Combination; Enzyme Induction; HIV Infections; HIV-1; Humans; Lymphoid Tissue; Reverse Transcriptase Inhibitors; Telomerase; Telomere; Up-Regulation; Zalcitabine; Zidovudine

1999
Concomitant therapy with subcutaneous interleukin-2 and zidovudine plus didanosine in patients with early stage HIV infection.
    Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association, 1999, Jan-01, Volume: 20, Issue:1

    Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; CD4-CD8 Ratio; Didanosine; DNA, Viral; Drug Therapy, Combination; Female; HIV Infections; Humans; Injections, Subcutaneous; Interleukin-2; Leukocyte Common Antigens; Male; Pilot Projects; Receptors, Interleukin-2; Zidovudine

1999
Dynamics of provirus load and lymphocyte subsets after interleukin 2 treatment in HIV-infected patients.
    AIDS research and human retroviruses, 1999, Jan-20, Volume: 15, Issue:2

    Topics: Acquired Immunodeficiency Syndrome; Adult; Anti-HIV Agents; CD4-CD8 Ratio; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Didanosine; Female; HIV; Humans; Interleukin-2; Male; Polymerase Chain Reaction; Proviruses; Recombinant Proteins; T-Lymphocyte Subsets; Viral Load; Zidovudine

1999
Antiretroviral drugs: new agents, new combinations line up against HIV.
    Hospital technology series, 1996, Volume: 15, Issue:1

    Topics: Antiviral Agents; Australia; Didanosine; Drug Therapy, Combination; Europe; HIV; HIV Infections; Humans; Lamivudine; Multicenter Studies as Topic; Randomized Controlled Trials as Topic; Reverse Transcriptase Inhibitors; Ritonavir; Thiazoles; United States; Valine; Zalcitabine; Zidovudine

1996
Patients with HIV-1 RNA below 1000 copies/ml after 48 weeks on dual nucleoside combination therapy. Delta Coordinating Committee.
    AIDS (London, England), 1999, Feb-25, Volume: 13, Issue:3

    Topics: Adult; Anti-HIV Agents; Didanosine; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Reverse Transcriptase Inhibitors; RNA, Viral; Time Factors; Treatment Outcome; Viral Load; Zalcitabine; Zidovudine

1999
Immune restoration does not invariably occur following long-term HIV-1 suppression during antiretroviral therapy. INCAS Study Group.
    AIDS (London, England), 1999, Feb-04, Volume: 13, Issue:2

    Topics: Adult; Aging; Anti-HIV Agents; Didanosine; Follow-Up Studies; HIV Infections; HIV-1; Humans; Immunologic Memory; Middle Aged; Nevirapine; Reverse Transcriptase Inhibitors; Time Factors; Zidovudine

1999
Management of liver failure in a haemophilic patient co-infected with human immunodeficiency and hepatitis C viruses.
    Clinical and laboratory haematology, 1999, Volume: 21, Issue:2

    Topics: Anti-Bacterial Agents; Anti-HIV Agents; Clarithromycin; Didanosine; Hemophilia A; Hepacivirus; Hepatitis C; HIV Infections; Humans; Liver Failure, Acute; Male; Middle Aged; Zidovudine

1999
Data and safety monitoring in the Concorde and Alpha trials.
    Controlled clinical trials, 1999, Volume: 20, Issue:3

    Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Biomarkers; Didanosine; Double-Blind Method; Humans; Randomized Controlled Trials as Topic; Survival Analysis; Zidovudine

1999
Data and safety monitoring in the Delta trial.
    Controlled clinical trials, 1999, Volume: 20, Issue:3

    Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Didanosine; Double-Blind Method; Drug Therapy, Combination; Humans; Multicenter Studies as Topic; Randomized Controlled Trials as Topic; Survival Analysis; Zalcitabine; Zidovudine

1999
Comparative fitness of multi-dideoxynucleoside-resistant human immunodeficiency virus type 1 (HIV-1) in an In vitro competitive HIV-1 replication assay.
    Journal of virology, 1999, Volume: 73, Issue:7

    Topics: Adaptation, Biological; Animals; Anti-HIV Agents; COS Cells; Didanosine; Dideoxynucleosides; Drug Resistance, Microbial; Drug Resistance, Multiple; Genetic Variation; HeLa Cells; HIV-1; Humans; Reverse Transcriptase Inhibitors; Tumor Cells, Cultured; Virus Replication; Zidovudine

1999
Relevance of AIDS treatment with two nucleoside analogues alone.
    Lancet (London, England), 1999, Jun-12, Volume: 353, Issue:9169

    Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Didanosine; Drug Therapy, Combination; Humans; Survival Rate; Zalcitabine; Zidovudine

1999
Intracellular activation of 2',3'-dideoxyinosine and drug interactions in vitro.
    AIDS research and human retroviruses, 1999, Jun-10, Volume: 15, Issue:9

    Topics: Anti-HIV Agents; Deoxyadenine Nucleotides; Didanosine; Dideoxynucleotides; Drug Interactions; Guanosine; Humans; Hydroxyurea; Inosine; Intracellular Fluid; Lamivudine; Pentoxifylline; Stavudine; U937 Cells; Zidovudine

1999
Reconstitution of human thymic implants is limited by human immunodeficiency virus breakthrough during antiretroviral therapy.
    Journal of virology, 1999, Volume: 73, Issue:8

    Topics: Animals; Anti-HIV Agents; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Didanosine; Disease Models, Animal; Drug Therapy, Combination; Hematopoietic Stem Cell Transplantation; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Indinavir; Kinetics; Lymphocyte Depletion; Mice; Mice, SCID; Reverse Transcriptase Inhibitors; Thymus Gland; Zidovudine

1999
Changing cost of English HIV service provision 1996-1997. NPMS Steering Group. National Prospective Monitoring System.
    International journal of STD & AIDS, 1999, Volume: 10, Issue:6

    Topics: Adult; Anti-HIV Agents; Didanosine; Drug Costs; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; Hospital Costs; Humans; Nevirapine; RNA-Directed DNA Polymerase; United Kingdom; Zalcitabine; Zidovudine

1999
Severe lactic acidosis induced by nucleoside analogues in an HIV-infected man.
    Annals of emergency medicine, 1999, Volume: 34, Issue:2

    Topics: Acidosis, Lactic; Adult; Anti-HIV Agents; Antimetabolites; Didanosine; Humans; Male; Zidovudine

1999
Beneficial effect of highly active antiretroviral therapy (HAART) in reducing both HIV viral load and monoclonal gammopathy.
    European journal of haematology, 1999, Volume: 63, Issue:2

    Topics: Adult; Anti-HIV Agents; B-Lymphocytes; Didanosine; Drug Therapy, Combination; HIV Infections; Humans; Lymphocyte Activation; Male; Paraproteinemias; Ritonavir; Viral Load; Zidovudine

1999
Efficacy of antiretroviral agents against murine replication-competent retrovirus infection in human cells.
    Journal of virology, 1999, Volume: 73, Issue:10

    Topics: Cell Line; Didanosine; Gene Transfer Techniques; Genetic Therapy; Genetic Vectors; Humans; Indinavir; Leukemia Virus, Murine; Reverse Transcriptase Inhibitors; Virus Replication; Zidovudine

1999
Emergence of zidovudine and multidrug-resistance mutations in the HIV-1 reverse transcriptase gene in therapy-naive patients receiving stavudine plus didanosine combination therapy. STADI Group.
    AIDS (London, England), 1999, Sep-10, Volume: 13, Issue:13

    Topics: Adult; Anti-HIV Agents; Didanosine; Drug Resistance, Multiple; Drug Therapy, Combination; HIV Infections; HIV Reverse Transcriptase; Humans; Mutation; Reverse Transcriptase Inhibitors; Stavudine; Viral Load; Zidovudine

1999
Inhibition of telomerase activity and cell proliferation by a reverse transcriptase inhibitor in gynaecological cancer cell lines.
    European journal of cancer (Oxford, England : 1990), 1999, Volume: 35, Issue:6

    Topics: Blotting, Southern; Cell Division; Cystadenocarcinoma; Didanosine; Dideoxynucleotides; Endometrial Neoplasms; Female; HIV Reverse Transcriptase; Humans; Reverse Transcriptase Inhibitors; Reverse Transcriptase Polymerase Chain Reaction; Telomerase; Thymine Nucleotides; Tumor Cells, Cultured; Uterine Neoplasms; Zidovudine

1999
Zidovudine (AZT) induced alterations in mitochondrial biogenesis in rat striated muscles.
    Canadian journal of physiology and pharmacology, 1999, Volume: 77, Issue:1

    Topics: Animals; Blood Pressure; Didanosine; DNA-Binding Proteins; Electron Transport Complex IV; Male; Mitochondria, Muscle; NF-E2-Related Factor 1; Nuclear Respiratory Factor 1; Nuclear Respiratory Factors; Rats; Rats, Sprague-Dawley; RNA, Messenger; Trans-Activators; Xenopus Proteins; Zidovudine

1999
Reaction times are faster in HIV-seropositive patients on antiretroviral therapy: A preliminary report.
    Journal of clinical and experimental neuropsychology, 1999, Volume: 21, Issue:5

    Topics: Adult; Anti-HIV Agents; Case-Control Studies; CD4 Lymphocyte Count; CD4-CD8 Ratio; Choice Behavior; Cognition; Cross-Sectional Studies; Didanosine; Drug Therapy, Combination; Female; HIV Infections; Humans; Male; Pilot Projects; Psychiatric Status Rating Scales; Psychomotor Performance; Reaction Time; Statistics, Nonparametric; Zalcitabine; Zidovudine

1999
Highly active anti-retroviral therapy (HAART) is associated with a lower level of CD4+ T cell apoptosis in HIV-infected patients.
    Clinical and experimental immunology, 1999, Volume: 118, Issue:3

    Topics: Adult; Aged; Anti-HIV Agents; Apoptosis; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Didanosine; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; Humans; Lamivudine; Male; Middle Aged; Multivariate Analysis; Retrospective Studies; Stavudine; Viral Load; Zalcitabine; Zidovudine

1999
Incidence and predictors of virologic failure of antiretroviral triple-drug therapy in a community-based cohort.
    AIDS research and human retroviruses, 1999, Dec-10, Volume: 15, Issue:18

    Topics: Adult; Aged; Anti-HIV Agents; CD4 Lymphocyte Count; Cohort Studies; Didanosine; Disease Progression; Drug Administration Schedule; Drug Resistance, Microbial; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Incidence; Indinavir; Lamivudine; Male; Middle Aged; Reverse Transcriptase Inhibitors; Risk Factors; Ritonavir; RNA, Viral; Salvage Therapy; Saquinavir; Stavudine; Switzerland; Treatment Failure; Viral Load; Zalcitabine; Zidovudine

1999
Evaluation of antiretroviral drug efficacy for HIV-1 encephalitis in SCID mice.
    Neurology, 2000, Jan-25, Volume: 54, Issue:2

    Topics: AIDS Dementia Complex; Animals; Cells, Cultured; Didanosine; Dideoxynucleosides; Disease Models, Animal; HIV-1; Humans; Lamivudine; Male; Mice; Mice, SCID; Monocytes; Reverse Transcriptase Inhibitors; Stavudine; Virus Replication; Zidovudine

2000
Presence of genotypic resistance in nucleoside analogue-treated HIV-1-infected patients with undetectable viral load.
    Antiviral therapy, 1999, Volume: 4, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Didanosine; Drug Resistance; Genes, pol; Genotype; HIV-1; Humans; Lamivudine; Point Mutation; RNA, Viral; Zalcitabine; Zidovudine

1999
A combination of nucleoside analogues and a protease inhibitor reduces HIV-1 RNA levels in semen: implications for sexual transmission of HIV infection.
    Antiviral therapy, 1999, Volume: 4, Issue:2

    Topics: Acquired Immunodeficiency Syndrome; Adult; Didanosine; Drug Therapy, Combination; HIV Protease Inhibitors; HIV-1; Humans; Male; Reverse Transcriptase Polymerase Chain Reaction; RNA, Viral; Semen; Sexually Transmitted Diseases; Zidovudine

1999
Different outcome in the first two patients with an HIV-1 multinucleoside drug-resistant T69SSS insertion in Spain.
    Antiviral therapy, 1999, Volume: 4, Issue:2

    Topics: Acquired Immunodeficiency Syndrome; Adult; Anti-HIV Agents; Didanosine; Drug Resistance, Multiple; HIV Reverse Transcriptase; HIV-1; Humans; Male; Mutation; Spain; Zalcitabine; Zidovudine

1999
Drugs for HIV infection.
    The Medical letter on drugs and therapeutics, 2000, Jan-10, Volume: 42, Issue:1069

    Topics: Anti-HIV Agents; Didanosine; Dideoxynucleosides; Drug Costs; Drug Therapy, Combination; Female; HIV Infections; Humans; Infectious Disease Transmission, Vertical; Lamivudine; Pregnancy; Pregnancy Complications, Infectious; Reverse Transcriptase Inhibitors; Stavudine; Zalcitabine; Zidovudine

2000
Functional reconstitution of thymopoiesis after human immunodeficiency virus infection.
    Journal of virology, 2000, Volume: 74, Issue:6

    Topics: Animals; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Didanosine; Disease Models, Animal; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Indinavir; Mice; Mice, SCID; Receptors, Antigen, T-Cell, alpha-beta; Reverse Transcriptase Inhibitors; Thymus Gland; Zidovudine

2000
Initiation of antiretroviral therapy during primary HIV-1 infection induces rapid stabilization of the T-cell receptor beta chain repertoire and reduces the level of T-cell oligoclonality.
    Blood, 2000, Mar-01, Volume: 95, Issue:5

    Topics: Acute Disease; Anti-HIV Agents; Clone Cells; Didanosine; Drug Administration Schedule; Drug Therapy, Combination; Gene Rearrangement, beta-Chain T-Cell Antigen Receptor; HIV Infections; HIV Protease Inhibitors; HIV Reverse Transcriptase; HIV-1; Humans; Indinavir; Lamivudine; Lymphocyte Activation; Polymerase Chain Reaction; RNA-Directed DNA Polymerase; Saquinavir; T-Lymphocytes, Cytotoxic; Viremia; Zidovudine

2000
Phenotypic and genotypic resistance patterns of HIV-1 isolates derived from individuals treated with didanosine and stavudine.
    AIDS (London, England), 2000, Jan-28, Volume: 14, Issue:2

    Topics: Anti-HIV Agents; Didanosine; Drug Resistance, Microbial; Drug Resistance, Multiple; Drug Therapy, Combination; Follow-Up Studies; Genotype; HIV Infections; HIV-1; Humans; Mutation; Phenotype; Polymerase Chain Reaction; RNA-Directed DNA Polymerase; RNA, Viral; Stavudine; Viral Load; Zidovudine

2000
Early immune reconstitution after potent antiretroviral therapy in HIV-infected children correlates with the increase in thymus volume.
    AIDS (London, England), 2000, Feb-18, Volume: 14, Issue:3

    Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Child; Cohort Studies; Didanosine; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Organ Size; Reverse Transcriptase Inhibitors; Stavudine; Thymus Gland; Viral Load; Zidovudine

2000
HIV-associated bacteremia: how it has changed in the highly active antiretroviral therapy (HAART) era.
    Journal of acquired immune deficiency syndromes (1999), 2000, Feb-01, Volume: 23, Issue:2

    Topics: Adult; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Bacteremia; Community-Acquired Infections; Cross Infection; Didanosine; Drug Therapy, Combination; Female; Humans; Incidence; Male; Prospective Studies; Risk Factors; Viral Load; Zalcitabine; Zidovudine

2000
Baseline HIV type 1 genotypic resistance to a newly added nucleoside analog is predictive of virologic failure of the new therapy.
    AIDS research and human retroviruses, 2000, Apr-10, Volume: 16, Issue:6

    Topics: CD4 Lymphocyte Count; Didanosine; Drug Resistance, Microbial; Female; Genotype; HIV Infections; HIV-1; Humans; Lamivudine; Male; Mutation; Polymerase Chain Reaction; Predictive Value of Tests; Retrospective Studies; Reverse Transcriptase Inhibitors; RNA, Viral; Viral Load; Zalcitabine; Zidovudine

2000
Decreased HIV-associated T cell apoptosis by HIV protease inhibitors.
    AIDS research and human retroviruses, 2000, Apr-10, Volume: 16, Issue:6

    Topics: Apoptosis; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cells, Cultured; Didanosine; HIV Infections; HIV Protease Inhibitors; HIV Seropositivity; HIV-1; Humans; Jurkat Cells; Nelfinavir; Reverse Transcriptase Inhibitors; Ritonavir; Saquinavir; T-Lymphocytes; Viral Load; Zidovudine

2000
Convergent evolution of reverse transcriptase (RT) genes of human immunodeficiency virus type 1 subtypes E and B following nucleoside analogue RT inhibitor therapies.
    Journal of virology, 2000, Volume: 74, Issue:11

    Topics: Amino Acid Sequence; Amino Acid Substitution; Anti-HIV Agents; Base Sequence; Didanosine; DNA, Viral; Drug Resistance, Microbial; Evolution, Molecular; Female; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Male; Molecular Sequence Data; Protein Structure, Secondary; Reverse Transcriptase Inhibitors; Zidovudine

2000
Does brain penetration of anti-HIV drugs matter?
    Sexually transmitted infections, 2000, Volume: 76, Issue:1

    Topics: AIDS Dementia Complex; Anti-HIV Agents; Brain; Didanosine; HIV-1; Humans; Zidovudine

2000
Cutaneous side effects induced by indinavir.
    European journal of dermatology : EJD, 2000, Volume: 10, Issue:4

    Topics: Adult; Alopecia; Didanosine; Drug Eruptions; Drug Therapy, Combination; Female; HIV; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Lipodystrophy; Male; Middle Aged; Pruritus; Pyoderma Gangrenosum; Retrospective Studies; Reverse Transcriptase Inhibitors; RNA, Viral; Scalp Dermatoses; Skin; Stavudine; Zalcitabine; Zidovudine

2000
GEE with Gaussian estimation of the correlations when data are incomplete.
    Biometrics, 2000, Volume: 56, Issue:2

    Topics: Anti-HIV Agents; Biometry; Computer Simulation; Controlled Clinical Trials as Topic; Didanosine; HIV Infections; Humans; Longitudinal Studies; Models, Statistical; Normal Distribution; Zidovudine

2000
Contribution of nucleoside analogue reverse transcriptase inhibitors to subcutaneous fat wasting in patients with HIV infection.
    AIDS (London, England), 2000, Jul-07, Volume: 14, Issue:10

    Topics: Absorptiometry, Photon; Adipose Tissue; Adult; Cohort Studies; Didanosine; Female; HIV Infections; HIV Protease Inhibitors; HIV Wasting Syndrome; Humans; Lamivudine; Longitudinal Studies; Male; Middle Aged; Reverse Transcriptase Inhibitors; Risk Factors; Stavudine; Time Factors; Zidovudine

2000
Assessment of developmental toxicity of antiretroviral drugs using a rat whole embryo culture system.
    Teratology, 2000, Volume: 62, Issue:2

    Topics: Abnormalities, Drug-Induced; Animals; Anti-HIV Agents; Crown-Rump Length; Didanosine; Drug Therapy, Combination; Embryo, Mammalian; Female; HIV Protease Inhibitors; Indinavir; Organ Culture Techniques; Pregnancy; Rats; Rats, Sprague-Dawley; Zalcitabine; Zidovudine

2000
Drug resistance and drug combination features of the human immunodeficiency virus inhibitor, BCH-10652 [(+/-)-2'-deoxy-3'-oxa-4'-thiocytidine, dOTC].
    Antiviral chemistry & chemotherapy, 2000, Volume: 11, Issue:4

    Topics: Anti-HIV Agents; Cells, Cultured; Deoxycytidine; Didanosine; Drug Combinations; Drug Resistance, Microbial; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Indinavir; Lamivudine; Molecular Structure; Mutation; Nevirapine; Reverse Transcriptase Inhibitors; Ritonavir; Saquinavir; Stavudine; T-Lymphocytes; Thionucleosides; Zidovudine

2000
[Perinatal co-infection with hepatitis B and HIV viruses--reciprocal effect of the disease and the treatment].
    Harefuah, 1999, May-16, Volume: 136, Issue:10

    Topics: Anti-HIV Agents; Didanosine; Female; Hepatitis B; HIV Infections; Humans; Infant; Ritonavir; Zidovudine

1999
Prevalence of multiple dideoxynucleoside analogue resistance (MddNR) in a multicenter cohort of HIV-1-infected Italian patients with virologic failure.
    Journal of acquired immune deficiency syndromes (1999), 2000, Jul-01, Volume: 24, Issue:3

    Topics: Acquired Immunodeficiency Syndrome; Adult; Aged; Amino Acid Sequence; Cohort Studies; Consensus Sequence; Didanosine; Dideoxynucleosides; Drug Resistance, Microbial; Drug Resistance, Multiple; Drug Therapy, Combination; Female; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Italy; Male; Middle Aged; Molecular Sequence Data; Multicenter Studies as Topic; Mutagenesis, Insertional; Mutation; Prevalence; Protease Inhibitors; Reverse Transcriptase Inhibitors; Zidovudine

2000
[Cost effectiveness analysis of highly active antiretroviral therapy in HIV asymptomatic patients].
    Medicina clinica, 2000, Volume: 114 Suppl 3

    Topics: Adult; Anti-HIV Agents; Cost-Benefit Analysis; Didanosine; Drug Therapy, Combination; Female; HIV Seropositivity; Humans; Indinavir; Lamivudine; Male; Middle Aged; Nevirapine; Sickness Impact Profile; Spain; Stavudine; Viral Load; Zidovudine

2000
Evidence of a role for the Q151L mutation and the viral background in development of multiple dideoxynucleoside-resistant human immunodeficiency virus type 1.
    Journal of virology, 2000, Volume: 74, Issue:20

    Topics: Amino Acid Sequence; Anti-HIV Agents; Didanosine; Drug Resistance; HIV Reverse Transcriptase; HIV-1; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; Virus Replication; Zalcitabine; Zidovudine

2000
Zidovudine-didanosine coexposure potentiates DNA incorporation of zidovudine and mutagenesis in human cells.
    Proceedings of the National Academy of Sciences of the United States of America, 2000, Nov-07, Volume: 97, Issue:23

    Topics: Anti-HIV Agents; Cell Survival; Cells, Cultured; Didanosine; DNA; Drug Synergism; Humans; Hypoxanthine Phosphoribosyltransferase; Mutagenesis; Reverse Transcriptase Inhibitors; Zidovudine

2000
Antiviral resistance of biologic HIV-2 clones obtained from individuals on nucleoside reverse transcriptase inhibitor therapy.
    Journal of acquired immune deficiency syndromes (1999), 2000, Sep-01, Volume: 25, Issue:1

    Topics: Adult; Amino Acid Sequence; Consensus Sequence; Didanosine; Drug Resistance, Microbial; Drug Therapy, Combination; Female; Genes, Viral; Genotype; HIV Infections; HIV-2; Humans; Lamivudine; Male; Molecular Sequence Data; Phenotype; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Zidovudine

2000
Monotherapy in an era of combination therapy: is there a benefit? Experience in HIV-1-infected symptomatic South African children.
    Annals of tropical paediatrics, 2000, Volume: 20, Issue:3

    Topics: Anti-HIV Agents; Didanosine; Drug Therapy, Combination; Female; Follow-Up Studies; Health Care Rationing; HIV Infections; HIV-1; Hospitalization; Humans; Infant; Male; Retrospective Studies; Reverse Transcriptase Inhibitors; South Africa; Treatment Outcome; Zidovudine

2000
Antiretroviral agents inhibit infection of human cells by porcine endogenous retroviruses.
    Antimicrobial agents and chemotherapy, 2000, Volume: 44, Issue:12

    Topics: Amino Acid Sequence; Animals; Anti-HIV Agents; Cells, Cultured; Didanosine; Humans; Microbial Sensitivity Tests; Molecular Sequence Data; Retroviridae; Sequence Homology, Amino Acid; Swine Diseases; Virus Replication; Zidovudine

2000
Evidence for late stage compartmentalization of HIV-1 resistance mutations between lymph node and peripheral blood mononuclear cells.
    AIDS (London, England), 2000, Oct-20, Volume: 14, Issue:15

    Topics: Anti-HIV Agents; Didanosine; Drug Resistance, Microbial; Evolution, Molecular; Genes, env; Genes, pol; Genetic Variation; HIV Envelope Protein gp120; HIV Infections; HIV-1; Humans; Leukocytes, Mononuclear; Lymph Nodes; Male; Mutation; Peptide Fragments; Time Factors; Zidovudine

2000
A genotypic analysis of patients receiving Zidovudine with either Lamivudine, Didanosine or Zalcitabine dual therapy using the LiPA point mutation assay to detect genotypic variation at codons 41, 69, 70, 74, 184 and 215.
    Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2000, Volume: 19, Issue:3

    Topics: Anti-HIV Agents; Codon; Didanosine; Drug Resistance, Microbial; Drug Resistance, Multiple; Drug Therapy, Combination; Genotype; HIV Infections; HIV Seropositivity; HIV-1; Humans; Lamivudine; Nucleic Acid Hybridization; Point Mutation; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Zalcitabine; Zidovudine

2000
Suppression of maternal virus load with zidovudine, didanosine, and indinavir combination therapy prevents mother-to-fetus HIV transmission in macaques.
    Journal of acquired immune deficiency syndromes (1999), 2000, Oct-01, Volume: 25, Issue:2

    Topics: Animals; Didanosine; Drug Therapy, Combination; Female; Fetus; HIV Antibodies; HIV Infections; HIV Protease Inhibitors; HIV-2; Indinavir; Infectious Disease Transmission, Vertical; Macaca nemestrina; Pregnancy; Reverse Transcriptase Inhibitors; T-Lymphocyte Subsets; Viral Load; Zidovudine

2000
Sustained responses to dual nucleoside therapy in women.
    Journal of acquired immune deficiency syndromes (1999), 2000, Dec-01, Volume: 25, Issue:4

    Topics: Adult; CD4 Lymphocyte Count; Didanosine; Drug Therapy, Combination; Female; HIV Infections; Humans; Lamivudine; Middle Aged; Reverse Transcriptase Inhibitors; Stavudine; Viral Load; Zidovudine

2000
Synergistic inhibition of HIV-1 in activated and resting peripheral blood mononuclear cells, monocyte-derived macrophages, and selected drug-resistant isolates with nucleoside analogues combined with a natural product, resveratrol.
    Journal of acquired immune deficiency syndromes (1999), 2000, Nov-01, Volume: 25, Issue:3

    Topics: Cell Division; Didanosine; Dose-Response Relationship, Drug; Drug Resistance; Drug Synergism; HIV-1; Humans; Hydroxyurea; Leukocytes, Mononuclear; Macrophages; Nucleosides; Resveratrol; Stilbenes; Virus Replication; Zalcitabine; Zidovudine

2000
Poor response to interferon treatment for chronic hepatitis C in human immunodeficiency virus-infected haemophiliacs.
    Haemophilia : the official journal of the World Federation of Hemophilia, 2000, Volume: 6, Issue:6

    Topics: Adult; Anti-HIV Agents; Antiviral Agents; Didanosine; Hemophilia A; Hepatitis C, Chronic; HIV Infections; Humans; Interferon-alpha; Middle Aged; Pilot Projects; Treatment Outcome; Zidovudine

2000
Phenotypic resistance pattern of HIV-1 isolates with zidovudine and/or multidrug resistance mutations after didanosine-stavudine combination therapy.
    Journal of acquired immune deficiency syndromes (1999), 2000, Dec-15, Volume: 25, Issue:5

    Topics: Anti-HIV Agents; Didanosine; Drug Resistance, Microbial; Drug Resistance, Multiple; Drug Therapy, Combination; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Mutation; Phenotype; Reverse Transcriptase Inhibitors; Stavudine; Viral Load; Zidovudine

2000
Protease inhibitor therapy in HIV-infected children.
    AIDS patient care and STDs, 2000, Volume: 14, Issue:11

    Topics: Adolescent; Age Factors; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Child; Child, Preschool; Didanosine; Female; HIV Infections; HIV Protease Inhibitors; Humans; Infant; Lamivudine; Male; Nelfinavir; Patient Compliance; Retrospective Studies; Stavudine; Treatment Outcome; Viral Load; Zidovudine

2000
Detection of resistant mutations in the reverse transcriptase of HIV-1-infected children.
    Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 2000, Volume: 6, Issue:5

    Topics: CD4 Lymphocyte Count; Child; Child, Preschool; Didanosine; Drug Resistance, Microbial; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; HIV Reverse Transcriptase; HIV-1; Humans; Infant; Male; Mutation; Reverse Transcriptase Inhibitors; Ritonavir; Viremia; Zidovudine

2000
Feasibility of postexposure prophylaxis (PEP) against human immunodeficiency virus infection after sexual or injection drug use exposure: the San Francisco PEP Study.
    The Journal of infectious diseases, 2001, Mar-01, Volume: 183, Issue:5

    Topics: Adolescent; Adult; Aged; Anti-HIV Agents; Contact Tracing; Counseling; Didanosine; Female; HIV Infections; Humans; Lamivudine; Male; Middle Aged; Nelfinavir; Patient Compliance; Reverse Transcriptase Inhibitors; Risk Factors; Risk-Taking; Sexually Transmitted Diseases, Viral; Substance Abuse, Intravenous; Time Factors; Zidovudine

2001
Treatment interruption after one year of triple nucleoside analogue therapy for primary HIV infection.
    AIDS (London, England), 2001, Jan-26, Volume: 15, Issue:2

    Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Didanosine; Drug Therapy, Combination; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Reverse Transcriptase Inhibitors; Time Factors; Viral Load; Zidovudine

2001
Leukocytopenia due to zidovudine- and nevirapine-containing regimens in elderly patients with HIV infection.
    Japanese journal of infectious diseases, 2000, Volume: 53, Issue:6

    Topics: Aged; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Didanosine; Drug Therapy, Combination; Fatal Outcome; Granulocyte Colony-Stimulating Factor; HIV Infections; HIV-1; Humans; Leukopenia; Male; Middle Aged; Nevirapine; Reverse Transcriptase Inhibitors; Zidovudine

2000
[Bilateral hip necrosis, corticoids, and human immunodeficiency virus protease inhibitors].
    Enfermedades infecciosas y microbiologia clinica, 2001, Volume: 19, Issue:1

    Topics: Aged; Antiretroviral Therapy, Highly Active; Dexamethasone; Didanosine; Femur Head Necrosis; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Male; Prednisone; Zidovudine

2001
Vertical HIV-1 transmission: prophylaxis and paediatric follow-up.
    Placenta, 2001, Volume: 22 Suppl A

    Topics: Acquired Immunodeficiency Syndrome; Adolescent; Adult; Anti-HIV Agents; Didanosine; Drug Therapy, Combination; Female; Follow-Up Studies; HIV-1; Humans; Infectious Disease Transmission, Vertical; Lamivudine; Pregnancy; Pregnancy Complications, Infectious; Pregnancy Outcome; Ritonavir; Viral Load; Zidovudine

2001
Incidence of pancreatitis in HIV-infected patients receiving nucleoside reverse transcriptase inhibitor drugs.
    AIDS (London, England), 2001, Mar-30, Volume: 15, Issue:5

    Topics: Adult; Amylases; Anti-HIV Agents; Didanosine; Female; HIV Infections; HIV-1; Humans; Hydroxyurea; Incidence; Lipase; Longitudinal Studies; Male; Pancreatitis; Reverse Transcriptase Inhibitors; Stavudine; United States; Zidovudine

2001
Predictive value of codon 215 reverse transcriptase mutation on the efficacy of didanosine in HIV-infected, zidovudine-experienced patients.
    Antiviral therapy, 1996, Volume: 1, Issue:3

    Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Codon; Didanosine; Female; HIV Infections; HIV Reverse Transcriptase; Humans; Male; Mutation; Retrospective Studies; Survival Rate; Zidovudine

1996
A bend in the road--implications of ACTG 175 and Delta trials.
    Antiviral therapy, 1996, Volume: 1, Issue:1

    Topics: Anti-HIV Agents; Australia; Clinical Trials as Topic; Didanosine; Drug Therapy, Combination; Europe; HIV Infections; HIV-1; Humans; Survival Analysis; United States; Zalcitabine; Zidovudine

1996
Zidovudine plus didanosine in primary HIV-1 infection.
    Antiviral therapy, 1997, Volume: 2, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Adult; Anti-HIV Agents; CD4-CD8 Ratio; Didanosine; Drug Therapy, Combination; Female; HIV-1; Humans; Male; Middle Aged; RNA, Viral; Zidovudine

1997
Fatal portal hypertension, liver failure, and mitochondrial dysfunction after HIV-1 nucleoside analogue-induced hepatitis and lactic acidaemia.
    Lancet (London, England), 2001, May-05, Volume: 357, Issue:9266

    Topics: Acute Disease; Aged; Anti-HIV Agents; Chemical and Drug Induced Liver Injury; Didanosine; Fatal Outcome; Fatty Liver; HIV Infections; HIV-1; Humans; Hypertension, Portal; Male; Mitochondria, Liver; Stavudine; Zidovudine

2001
Trial data available.
    AIDS patient care, 1995, Volume: 9, Issue:1

    Topics: Didanosine; HIV Seropositivity; Humans; Zidovudine

1995
Anti-HIV therapy lowers risk of AIDS, death in patients with intermediate-stage HIV disease.
    AIDS patient care, 1995, Volume: 9, Issue:6

    Topics: Antiviral Agents; Clinical Trials as Topic; Didanosine; Drug Therapy, Combination; HIV Infections; Humans; Survival Rate; Zalcitabine; Zidovudine

1995
Triple therapy in previously untreated patients reduces viral load below limit of detection.
    AIDS patient care and STDs, 1996, Volume: 10, Issue:5

    Topics: Adult; Anti-HIV Agents; Didanosine; Drug Therapy, Combination; HIV Infections; Humans; Nevirapine; Pyridines; Viral Load; Zidovudine

1996
Crixivan reduces viral load.
    AIDS patient care and STDs, 1996, Volume: 10, Issue:1

    Topics: Anti-HIV Agents; Didanosine; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Viral Load; Zalcitabine; Zidovudine

1996
Research study of combination AIDS therapies underway.
    AIDS patient care and STDs, 1996, Volume: 10, Issue:2

    Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; CD4 Lymphocyte Count; Clinical Trials as Topic; Didanosine; Drug Therapy, Combination; Humans; Lamivudine; Zidovudine

1996
FDA clearance for ritonavir in children with AIDS.
    AIDS patient care and STDs, 1997, Volume: 11, Issue:3

    Topics: Acquired Immunodeficiency Syndrome; Adolescent; Anti-HIV Agents; Child; Child, Preschool; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Didanosine; Drug Approval; Drug Therapy, Combination; HIV Protease Inhibitors; Humans; Ritonavir; United States; United States Food and Drug Administration; Zidovudine

1997
Two studies suggest nevirapine benefit for children.
    AIDS patient care and STDs, 1997, Volume: 11, Issue:3

    Topics: Anti-HIV Agents; Clinical Trials as Topic; Didanosine; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Infant; Infant, Newborn; Infectious Disease Transmission, Vertical; Nevirapine; Pregnancy; Pyridines; Reverse Transcriptase Inhibitors; RNA, Viral; Zidovudine

1997
Viramune triple therapy shows suppression of HIV after 1 year, 7 months.
    AIDS patient care and STDs, 1997, Volume: 11, Issue:6

    Topics: Anti-HIV Agents; Didanosine; Drug Therapy, Combination; HIV Infections; Humans; Nevirapine; Zidovudine

1997
AZT studies reinforce benefits of combination.
    AIDS alert, 1995, Volume: 10, Issue:1

    Topics: Antiviral Agents; CD4-Positive T-Lymphocytes; Didanosine; Drug Synergism; Drug Therapy, Combination; HIV Infections; Humans; Lamivudine; Lymphocyte Count; Zalcitabine; Zidovudine

1995
Nevirapine triple combo results released.
    Common factor (Stoughton, Mass.), 1995, Issue:no 10

    Topics: Antiviral Agents; CD4 Lymphocyte Count; Clinical Trials as Topic; Didanosine; Drug Therapy, Combination; Erythema; HIV Infections; HIV-1; Humans; Nevirapine; Pyridines; Virus Replication; Zidovudine

1995
Treatment briefs.
    GMHC treatment issues : the Gay Men's Health Crisis newsletter of experimental AIDS therapies, 1995, Volume: 9, Issue:4

    Topics: CD4 Lymphocyte Count; Clinical Trials as Topic; Didanosine; Drug Industry; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Nerve Growth Factors; Nervous System Diseases; Pyridines; Recombinant Proteins; Stavudine; Zalcitabine; Zidovudine

1995
Results of pediatric study present new questions.
    PI perspective, 1995, Issue:no 16

    Topics: Adolescent; Child; Child, Preschool; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Didanosine; Drug Therapy, Combination; Female; HIV Infections; Humans; Infant; Pregnancy; Pregnancy Complications, Infectious; Quality of Health Care; Zidovudine

1995
CTG studies yield results. AIDS Clinical Trials Group.
    NIAID AIDS agenda, 1995,Spring

    Topics: Acyclovir; Child; Clinical Trials as Topic; Cytomegalovirus Infections; Didanosine; Drug Therapy, Combination; Fluconazole; HIV Infections; Humans; Mycoses; Pneumonia, Pneumocystis; Valacyclovir; Valine; Zidovudine

1995
What we know about anti-HIV drugs.
    Treatment review, 1995, Issue:no 18

    Topics: Antiviral Agents; Didanosine; DNA, Viral; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Lamivudine; RNA, Viral; Stavudine; Zalcitabine; Zidovudine

1995
Combination treatment and single drugs: interview with Margaret Poscher, M.D. Interview by John S. James.
    AIDS treatment news, 1995, Jul-07, Issue:no 226

    Topics: Acyclovir; Administration, Oral; Antiviral Agents; CD4 Lymphocyte Count; Didanosine; Drug Administration Schedule; Drug Resistance, Microbial; Drug Therapy, Combination; Ganciclovir; HIV Infections; Humans; Lamivudine; Stavudine; Zalcitabine; Zidovudine

1995
Combination treatment and single drugs: interview with Margaret Poscher, M.D. Interview by John S. James.
    AIDS treatment news, 1995, Jul-21, Issue:no 227

    Topics: Acquired Immunodeficiency Syndrome; Acyclovir; Antiviral Agents; CD4 Lymphocyte Count; Didanosine; Drug Approval; Drug Combinations; Drug Therapy, Combination; Health Services Accessibility; Humans; Insurance, Health; Lamivudine; Managed Care Programs; United States; Zalcitabine; Zidovudine

1995
Inmate not entitled to choose his own course of HIV medicines.
    AIDS policy & law, 1995, Jul-28, Volume: 10, Issue:13

    Topics: Acyclovir; Didanosine; Drug Therapy, Combination; HIV Seropositivity; Humans; Informed Consent; Male; New York; Patient Participation; Prisoners; Refusal to Treat; Zidovudine

1995
Antiretroviral drug resistance.
    AIDS clinical care, 1995, Volume: 7, Issue:8

    Topics: Antiviral Agents; CD4 Lymphocyte Count; Didanosine; Drug Resistance, Microbial; Drug Resistance, Multiple; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Lamivudine; RNA, Viral; Stavudine; Viremia; Zalcitabine; Zidovudine

1995
Update on clinical trials of combination therapies for HIV infection.
    NIAID AIDS agenda, 1995

    Topics: Adult; Antiviral Agents; CD4 Lymphocyte Count; Child; Clinical Trials as Topic; Didanosine; Drug Therapy, Combination; HIV Infections; Humans; Hydroxyurea; Lamivudine; RNA-Directed DNA Polymerase; Stavudine; Zalcitabine; Zidovudine

1995
Researchers are rethinking role of AZT in drug therapy.
    AIDS policy & law, 1995, Oct-06, Volume: 10, Issue:18

    Topics: Antiviral Agents; CD4 Lymphocyte Count; Didanosine; HIV Infections; Humans; United States; Zidovudine

1995
Update on HIV protease inhibitors.
    AIDS clinical care, 1995, Volume: 7, Issue:10

    Topics: Antiviral Agents; CD4 Lymphocyte Count; Clinical Trials as Topic; Didanosine; Drug Design; Drug Therapy, Combination; HIV Infections; HIV Protease; HIV Protease Inhibitors; Humans; Indinavir; Isoquinolines; Phosphorylation; Pyridines; Quinolines; Ritonavir; Saquinavir; Substrate Specificity; Thiazoles; Valine; Zalcitabine; Zidovudine

1995
Protease inhibitors and prevention of cross resistance.
    AIDS treatment news, 1995, Oct-06, Issue:no 232

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Carbamates; Didanosine; Drug Resistance, Microbial; Drug Therapy, Combination; Furans; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Indinavir; Isoquinolines; Lamivudine; Nelfinavir; Pyridines; Quinolines; Saquinavir; Sulfonamides; Zalcitabine; Zidovudine

1995
AZT delta study: major European/Australian study finds combinations better than AZT alone.
    AIDS treatment news, 1995, Oct-06, Issue:no 232

    Topics: Acquired Immunodeficiency Syndrome; CD4 Lymphocyte Count; Clinical Trials as Topic; Didanosine; Drug Therapy, Combination; Humans; Zalcitabine; Zidovudine

1995
ACTG 175 and Delta.
    GMHC treatment issues : the Gay Men's Health Crisis newsletter of experimental AIDS therapies, 1995, Volume: 9, Issue:10

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; CD4 Lymphocyte Count; Clinical Trials as Topic; Didanosine; Drug Therapy, Combination; Evaluation Studies as Topic; Humans; Treatment Outcome; Zalcitabine; Zidovudine

1995
Making sense of 175 and Delta.
    GMHC treatment issues : the Gay Men's Health Crisis newsletter of experimental AIDS therapies, 1995, Volume: 9, Issue:10

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Clinical Trials as Topic; Didanosine; Drug Approval; Drug Resistance, Microbial; Drug Therapy, Combination; Evaluation Studies as Topic; Humans; Zalcitabine; Zidovudine

1995
New trials reach same conclusion: two drugs are better than AZT alone.
    AIDS alert, 1995, Volume: 10, Issue:11

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; CD4 Lymphocyte Count; Clinical Trials as Topic; Data Interpretation, Statistical; Didanosine; Drug Therapy, Combination; Humans; Treatment Outcome; Zalcitabine; Zidovudine

1995
Study results at a glance.
    AIDS alert, 1995, Volume: 10, Issue:11

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Clinical Trials as Topic; Didanosine; Drug Therapy, Combination; Humans; Zalcitabine; Zidovudine

1995
Closing the circle on HIV--or not.
    Journal of the International Association of Physicians in AIDS Care, 1995, Volume: 1, Issue:9

    Topics: Antiviral Agents; Biomarkers; CD4 Lymphocyte Count; Clinical Trials as Topic; Didanosine; Drug Resistance, Microbial; Drug Therapy, Combination; HIV; HIV Infections; HIV Protease Inhibitors; Humans; Interleukin-2; Nelfinavir; Prognosis; RNA, Viral; Zalcitabine; Zidovudine

1995
Can the conundrums of ACTG 175 be solved? An interview with Martin S. Hirsch, MD.
    Journal of the International Association of Physicians in AIDS Care, 1995, Volume: 1, Issue:9

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Clinical Trials as Topic; Didanosine; Drug Therapy, Combination; Humans; Treatment Outcome; Zidovudine

1995
Review of viral load and combination therapy data from 35th Annual Interscience Conference on Antimicrobial Agents and Chemotherapy.
    STEP perspective, 1995,Winter, Volume: 7, Issue:3

    Topics: Antiviral Agents; CD4 Lymphocyte Count; Clinical Trials as Topic; Didanosine; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Male; Mutation; RNA, Viral; Zidovudine

1995
FDA triple header. Food and Drug Administration.
    GMHC treatment issues : the Gay Men's Health Crisis newsletter of experimental AIDS therapies, 1995, Volume: 9, Issue:11

    Topics: Acquired Immunodeficiency Syndrome; Adult; Antiviral Agents; CD4 Lymphocyte Count; Child; Didanosine; Drug Resistance, Microbial; Drug Therapy, Combination; HIV Protease Inhibitors; Humans; Isoquinolines; Lamivudine; Mutation; Quinolines; Salvage Therapy; Saquinavir; Stavudine; United States; United States Food and Drug Administration; Zalcitabine; Zidovudine

1995
Combination therapy increases survival.
    Treatment review, 1995, Issue:no 20

    Topics: Antiviral Agents; CD4 Lymphocyte Count; Clinical Trials as Topic; Didanosine; Drug Therapy, Combination; HIV Infections; Humans; Lamivudine; Stavudine; Zalcitabine; Zidovudine

1995
To treat or not to treat--approaches to antiretroviral therapy. Interview by Anthony J. Japour.
    AIDS clinical care, 1996, Volume: 8, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; CD4 Lymphocyte Count; Clinical Trials as Topic; Clinical Trials, Phase III as Topic; Didanosine; Drug Therapy, Combination; HIV; Humans; Lamivudine; Practice Patterns, Physicians'; RNA, Viral; Zalcitabine; Zidovudine

1996
Benefits of combination therapy confirmed.
    PI perspective, 1995, Issue:no 17

    Topics: Antiviral Agents; CD4 Lymphocyte Count; Clinical Trials as Topic; Didanosine; Drug Therapy, Combination; HIV Infections; Humans; Treatment Failure; Zalcitabine; Zidovudine

1995
Merck protease inhibitor: more news from Retroviruses Conference.
    AIDS treatment news, 1996, Feb-16, Issue:no 241

    Topics: CD4 Lymphocyte Count; Didanosine; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Pyridines; Zalcitabine; Zidovudine

1996
AZT, ddI, and ddC combinations at FDA advisory hearing. Food and Drug Administration.
    AIDS treatment news, 1996, Apr-05, Issue:no 244

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Clinical Trials as Topic; Didanosine; Drug Therapy, Combination; Humans; Zalcitabine; Zidovudine

1996
Europe out of step with the US.
    Journal of the International Association of Physicians in AIDS Care, 1996, Volume: 2, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Didanosine; Drug Costs; Europe; HIV Protease Inhibitors; Humans; Isoquinolines; Lamivudine; Quinolines; Ritonavir; Saquinavir; Thiazoles; United States; Valine; Zalcitabine; Zidovudine

1996
ACTG 175: new insights into treating patients with intermediate-stage HIV disease.
    NIAID AIDS agenda, 1995

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; CD4 Lymphocyte Count; Didanosine; Drug Therapy, Combination; Humans; Zalcitabine; Zidovudine

1995
Back to the nukes.
    GMHC treatment issues : the Gay Men's Health Crisis newsletter of experimental AIDS therapies, 1996, Volume: 10, Issue:2

    Topics: Antiviral Agents; CD4 Lymphocyte Count; Clinical Trials as Topic; Didanosine; Drug Therapy, Combination; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Stavudine; Zalcitabine; Zidovudine

1996
Pediatric treatment update.
    GMHC treatment issues : the Gay Men's Health Crisis newsletter of experimental AIDS therapies, 1996, Volume: 10, Issue:3

    Topics: Adolescent; Child; Child, Preschool; Didanosine; Drug Therapy, Combination; HIV Infections; Humans; Infant; Zidovudine

1996
Update on other antivirals.
    PI perspective, 1996, Issue:no 18

    Topics: Adenine; Antiviral Agents; Didanosine; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Organophosphonates; Stavudine; Zalcitabine; Zidovudine

1996
Nipping HIV in the bud.
    GMHC treatment issues : the Gay Men's Health Crisis newsletter of experimental AIDS therapies, 1996, Volume: 10, Issue:8

    Topics: Antiviral Agents; CD4 Lymphocyte Count; Didanosine; DNA, Viral; Drug Resistance, Microbial; Drug Therapy, Combination; HIV; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Isoquinolines; Lamivudine; Pyridines; Quinolines; Ritonavir; Saquinavir; Stavudine; Thiazoles; Valine; Virus Replication; Zalcitabine; Zidovudine

1996
Antiviral roundup.
    GMHC treatment issues : the Gay Men's Health Crisis newsletter of experimental AIDS therapies, 1996, Volume: 10, Issue:8

    Topics: CD4 Lymphocyte Count; Cohort Studies; Delavirdine; Didanosine; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; HIV Reverse Transcriptase; HIV-1; Humans; Indoles; Mutation; Piperazines; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Stavudine; Zidovudine

1996
Top AIDS researchers' strategy for antiretroviral treatment.
    AIDS alert, 1996, Volume: 11, Issue:9

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; CD4 Lymphocyte Count; Didanosine; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Patient Compliance; Practice Guidelines as Topic; RNA, Viral; Stavudine; Zalcitabine; Zidovudine

1996
Nevirapine: new drug, new class, new questions.
    Journal of the International Association of Physicians in AIDS Care, 1996, Volume: 2, Issue:7

    Topics: Adult; Antiviral Agents; CD4 Lymphocyte Count; Child; Didanosine; Drug Approval; Drug Therapy, Combination; HIV; HIV Infections; Humans; Nevirapine; Pyridines; Reverse Transcriptase Inhibitors; United States; United States Food and Drug Administration; Zidovudine

1996
3TC: combination trial stopped early as clinical benefit shown.
    AIDS treatment news, 1996, Aug-02, Issue:no 252

    Topics: Antiviral Agents; Clinical Trials as Topic; Didanosine; Disease Progression; Drug Therapy, Combination; HIV Infections; Humans; Lamivudine; Placebos; Treatment Failure; Zalcitabine; Zidovudine

1996
ACTG 152: new insights into pediatric antiretroviral therapy.
    NIAID AIDS agenda, 1996

    Topics: Adolescent; Antiviral Agents; Child; Child, Preschool; Didanosine; Drug Therapy, Combination; HIV Infections; Humans; Infant; Zidovudine

1996
Outdated yet out-of-reach: AIDS society treatment guidelines at the International Conference.
    GMHC treatment issues : the Gay Men's Health Crisis newsletter of experimental AIDS therapies, 1996, Volume: 10, Issue:9

    Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Opportunistic Infections; Antiviral Agents; CD4 Lymphocyte Count; Decision Making; Didanosine; Drug Therapy, Combination; HIV; HIV Infections; Humans; Lamivudine; Practice Guidelines as Topic; Zalcitabine; Zidovudine

1996
Nevirapine approved by FDA. Food and Drug Administration.
    NIAID AIDS agenda, 1996

    Topics: Antiviral Agents; CD4 Lymphocyte Count; Clinical Trials as Topic; Didanosine; Drug Approval; Drug Therapy, Combination; Female; HIV Infections; Infant, Newborn; Infectious Disease Transmission, Vertical; Nevirapine; Pregnancy; Pyridines; Reverse Transcriptase Inhibitors; United States; United States Food and Drug Administration; Viral Load; Zidovudine

1996
A patient's guide to protease inhibitors.
    AIDS clinical care, 1996, Volume: 8, Issue:10

    Topics: Anti-HIV Agents; Didanosine; Drug Administration Schedule; Drug Therapy, Combination; Eating; Guidelines as Topic; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Ritonavir; Saquinavir; Stavudine; Zidovudine

1996
ddI and d4T plus protease inhibitors.
    GMHC treatment issues : the Gay Men's Health Crisis newsletter of experimental AIDS therapies, 1996, Volume: 10, Issue:11

    Topics: Anti-HIV Agents; Didanosine; HIV Infections; Humans; Lamivudine; Stavudine; Zalcitabine; Zidovudine

1996
FDA advisory committee deadlocks on delavirdine. Food and Drug Administration.
    AIDS treatment news, 1996, Dec-06, Issue:No 260

    Topics: Antiviral Agents; CD4 Lymphocyte Count; Clinical Trials as Topic; Delavirdine; Didanosine; Disease Progression; Drug Approval; Drug Industry; Drug Interactions; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; Humans; Indoles; Piperazines; Reverse Transcriptase Inhibitors; United States; United States Food and Drug Administration; Viral Load; Zidovudine

1996
Dethroning AZT.
    GMHC treatment issues : the Gay Men's Health Crisis newsletter of experimental AIDS therapies, 1997, Volume: 11, Issue:2

    Topics: Alkynes; Anti-HIV Agents; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; Didanosine; Drug Therapy, Combination; HIV Infections; Humans; Hydroxyurea; Lamivudine; Oxazines; Stavudine; Viral Load; Zidovudine

1997
NIAID researchers present new findings at retrovirus meeting. National Institute of Allergy and Infectious Diseases.
    NIAID AIDS agenda, 1997

    Topics: Anti-HIV Agents; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; Chemokines; Clinical Trials as Topic; Clone Cells; Dendritic Cells; Didanosine; Disease Progression; Drug Therapy, Combination; Female; HIV; HIV Infections; HIV Protease Inhibitors; Humans; Interleukin-10; Killer Cells, Natural; Lamivudine; Male; Nevirapine; Pyridines; Receptors, Cytokine; Reverse Transcriptase Inhibitors; Ritonavir; Virus Replication; Zalcitabine; Zidovudine

1997
Delavirdine (Rescriptor) approved.
    AIDS treatment news, 1997, Apr-18, Issue:No 269

    Topics: Anti-HIV Agents; Delavirdine; Didanosine; Drug Approval; Drug Costs; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Indoles; Piperazines; Reverse Transcriptase Inhibitors; United States; United States Food and Drug Administration; Zidovudine

1997
Immune modulation with IL-2 and IL-12.
    STEP perspective, 1997,Winter, Volume: 9, Issue:1

    Topics: Anti-HIV Agents; CD4-Positive T-Lymphocytes; Cytokines; Didanosine; Drug Therapy, Combination; HIV Infections; Humans; Interleukin-12; Interleukin-2; Zidovudine

1997
Combo therapy for children and adolescents.
    Treatment review, 1997, Issue:No 25

    Topics: Adolescent; Anti-HIV Agents; Child; Child, Preschool; Clinical Trials as Topic; Didanosine; Disease Progression; Drug Therapy, Combination; HIV Infections; Humans; Infant; Lamivudine; Zidovudine

1997
Update on nevirapine: quest for a niche.
    Journal of the International Association of Physicians in AIDS Care, 1997, Volume: 3, Issue:9

    Topics: Adult; Anti-HIV Agents; Child; Clinical Trials as Topic; Didanosine; Drug Resistance, Microbial; Drug Synergism; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Infant; Infant, Newborn; Nevirapine; Reverse Transcriptase Inhibitors; Zalcitabine; Zidovudine

1997
Reevaluating initial therapy.
    GMHC treatment issues : the Gay Men's Health Crisis newsletter of experimental AIDS therapies, 1998, Volume: 12, Issue:2

    Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Clinical Trials as Topic; Didanosine; DNA, Viral; Drug Resistance, Microbial; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; Humans; Lamivudine; Polymerase Chain Reaction; Stavudine; Viral Load; Zidovudine

1998
Vertical transmission research at the Retrovirus Conference.
    GMHC treatment issues : the Gay Men's Health Crisis newsletter of experimental AIDS therapies, 1998, Volume: 12, Issue:3

    Topics: Anti-HIV Agents; Clinical Trials as Topic; Didanosine; Drug Resistance, Microbial; Female; HIV Infections; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Maternal-Fetal Exchange; Pregnancy; Pregnancy Complications, Infectious; Viral Load; Zidovudine

1998
Viral load--how low is best?
    TreatmentUpdate, 1998, Volume: 10, Issue:10

    Topics: Anti-HIV Agents; Didanosine; Drug Therapy, Combination; HIV Infections; Humans; Nevirapine; Reverse Transcriptase Inhibitors; Viral Load; Zidovudine

1998
Hydroxyurea, a potential new anti-HIV agent.
    GMHC treatment issues : the Gay Men's Health Crisis newsletter of experimental AIDS therapies, 1995, Volume: 9, Issue:1

    Topics: Didanosine; DNA Replication; Drug Therapy, Combination; HIV; HIV Infections; Humans; Hydroxyurea; Leukocytes, Mononuclear; Virus Replication; Zalcitabine; Zidovudine

1995
Antiretroviral therapy for adults and children.
    AIDS Institute newsletter. New York (State). AIDS Institute, 1995

    Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Child; Didanosine; Female; HIV Infections; Humans; Pregnancy; Pregnancy Complications, Infectious; Primary Health Care; Stavudine; Viral Load; Zalcitabine; Zidovudine

1995
[A rare etiology of hepatic steatosis associated with lactic acidosis: the toxicity of antiviral nucleoside analogues].
    Annales de pathologie, 2001, Volume: 21, Issue:2

    Topics: Acidosis, Lactic; Adult; Anti-HIV Agents; Antimetabolites; Didanosine; Fatal Outcome; Fatty Liver; Female; HIV Seropositivity; Humans; Lamivudine; Microscopy, Electron; Mitochondria, Liver; Stavudine; Zidovudine

2001
Choosing which nuke to use first.
    The AIDS reader, 2001, Volume: 11, Issue:5

    Topics: Didanosine; Dideoxynucleosides; Drug Administration Schedule; HIV Infections; Humans; Lamivudine; Reverse Transcriptase Inhibitors; Stavudine; Zidovudine

2001
[Symptomatic hyperlactemia in patients infected with the human immunodeficiency virus treated with nucleoside analogs].
    Medicina clinica, 2001, Jun-09, Volume: 117, Issue:1

    Topics: Adult; Anti-HIV Agents; Didanosine; Female; HIV Infections; HIV Reverse Transcriptase; Humans; Lactic Acid; Lamivudine; Male; Reverse Transcriptase Inhibitors; Zidovudine

2001
Quinoxalinylethylpyridylthioureas (QXPTs) as potent non-nucleoside HIV-1 reverse transcriptase (RT) inhibitors. Further SAR studies and identification of a novel orally bioavailable hydrazine-based antiviral agent.
    Journal of medicinal chemistry, 2001, Feb-01, Volume: 44, Issue:3

    Topics: Animals; Anti-HIV Agents; Biological Availability; Cell Line; Didanosine; Drug Synergism; HIV Reverse Transcriptase; HIV-1; Humans; Mice; Models, Molecular; Pyridines; Quinoxalines; Reverse Transcriptase Inhibitors; Stereoisomerism; Structure-Activity Relationship; Thiourea; Zidovudine

2001
HIV-1 multi-dideoxynucleoside resistance mutation (Q151M): prevalence, associated resistance mutations and response to antiretroviral salvage treatment.
    Microbios, 2001, Volume: 106, Issue:414

    Topics: Adult; Anti-HIV Agents; Didanosine; Drug Resistance, Multiple, Viral; Drug Therapy, Combination; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Mutation; Reverse Transcriptase Inhibitors; Salvage Therapy; Treatment Failure; Viral Load; Zidovudine

2001
Differential susceptibility of retroviruses to nucleoside analogues.
    Antiviral chemistry & chemotherapy, 2001, Volume: 12, Issue:2

    Topics: Animals; Antiviral Agents; Cell Line; Cricetinae; Didanosine; Dose-Response Relationship, Drug; Humans; Inhibitory Concentration 50; Lamivudine; Mink; Nucleosides; Retroviridae; Reverse Transcriptase Inhibitors; Stavudine; Substrate Specificity; Zalcitabine; Zidovudine

2001
Immunological and virological effects of long term IL-2 therapy in HIV-1-infected patients.
    AIDS (London, England), 2001, Sep-07, Volume: 15, Issue:13

    Topics: Anti-HIV Agents; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; Didanosine; DNA, Viral; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Immunologic Memory; Interleukin-2; Reverse Transcriptase Inhibitors; Time Factors; Zidovudine

2001
Innovative AIDS drug plan may be undermining testing.
    The New York times on the Web, 1989, Nov-21

    Topics: Acquired Immunodeficiency Syndrome; Didanosine; Federal Government; Government; Human Experimentation; Humans; Patient Care; Pharmaceutical Preparations; Public Policy; Research; Research Design; Therapeutic Human Experimentation; United States; Zidovudine

1989
Hyperlactatemia and antiretroviral therapy: the Swiss HIV Cohort Study.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2001, Dec-01, Volume: 33, Issue:11

    Topics: Acidosis, Lactic; Adult; Anti-HIV Agents; Cohort Studies; Didanosine; Female; HIV Infections; Humans; Male; Prevalence; Reverse Transcriptase Inhibitors; Risk Factors; Stavudine; Switzerland; Zidovudine

2001
Increased ability for selection of zidovudine resistance in a distinct class of wild-type HIV-1 from drug-naive persons.
    Proceedings of the National Academy of Sciences of the United States of America, 2001, Nov-20, Volume: 98, Issue:24

    Topics: Anti-HIV Agents; Base Sequence; Didanosine; Dideoxynucleosides; DNA, Viral; Drug Resistance, Viral; Evolution, Molecular; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Molecular Sequence Data; Mutagenesis; Recombination, Genetic; Reverse Transcriptase Inhibitors; Stavudine; Virus Replication; Zalcitabine; Zidovudine

2001
Drugs for HIV infection.
    The Medical letter on drugs and therapeutics, 2001, Nov-26, Volume: 43, Issue:1119

    Topics: Alkynes; Benzoxazines; Cyclopropanes; Delavirdine; Didanosine; Dose-Response Relationship, Drug; HIV Infections; HIV Protease Inhibitors; Humans; Nelfinavir; Nevirapine; Oxazines; Reverse Transcriptase Inhibitors; Saquinavir; Stavudine; Zidovudine

2001
Prevalence and genetic heterogeneity of the reverse transcriptase T69S-S-X insertion in pretreated HIV-infected patients.
    Intervirology, 2001, Volume: 44, Issue:6

    Topics: Anti-HIV Agents; Didanosine; Drug Resistance, Viral; Genetic Heterogeneity; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Male; Mutagenesis; Prevalence; Reverse Transcriptase Inhibitors; Spain; Zidovudine

2001
Lymphocytes proliferate in blood and lymph nodes following interleukin-2 therapy in addition to highly active antiretroviral therapy.
    AIDS (London, England), 2002, Jan-25, Volume: 16, Issue:2

    Topics: Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Apoptosis; B-Lymphocytes; CD4 Lymphocyte Count; CD8-Positive T-Lymphocytes; Cell Division; Didanosine; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Immunotherapy; Interleukin-2; Lymph Nodes; Male; Reverse Transcriptase Inhibitors; RNA, Viral; Saquinavir; T-Lymphocytes; Zidovudine

2002
Acanthosis nigricans: a new manifestation of insulin resistance in patients receiving treatment with protease inhibitors.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2002, Mar-01, Volume: 34, Issue:5

    Topics: Acanthosis Nigricans; Adult; Diabetes Mellitus; Didanosine; HIV Infections; HIV Protease Inhibitors; Humans; Insulin Resistance; Male; Ritonavir; Zidovudine

2002
Resistance to antiretroviral treatment in Gabon: need for implementation of guidelines on antiretroviral therapy use and HIV-1 drug resistance monitoring in developing countries.
    Journal of acquired immune deficiency syndromes (1999), 2002, Feb-01, Volume: 29, Issue:2

    Topics: Anti-HIV Agents; Developing Countries; Didanosine; Drug Resistance, Viral; Gabon; HIV Infections; HIV Protease; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Population Surveillance; Practice Guidelines as Topic; Reverse Transcriptase Inhibitors; Stavudine; Zidovudine

2002
Viral and immunologic follow up of 4 to 9 years of AIDS treatments by quadruple combinations of virostatics including integrase inhibitors applied in short sequences differing by drug rotation.
    Acta pharmacologica Sinica, 2002, Volume: 23, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Acriflavine; Adult; Anti-HIV Agents; Antiviral Agents; CD4-CD8 Ratio; Didanosine; Drug Therapy, Combination; Ellipticines; Female; Follow-Up Studies; HIV-1; Humans; Integrase Inhibitors; Male; Middle Aged; Protease Inhibitors; Stavudine; Vitamin B 12; Zalcitabine; Zidovudine

2002
Tenofovir exhibits low cytotoxicity in various human cell types: comparison with other nucleoside reverse transcriptase inhibitors.
    Antiviral research, 2002, Volume: 54, Issue:1

    Topics: Adenine; Anti-HIV Agents; Antigens, CD34; Cell Line; Didanosine; Dideoxynucleosides; Epithelial Cells; Hematopoietic Stem Cells; Humans; Kidney Tubules, Proximal; Liver; Muscle, Skeletal; Organophosphonates; Organophosphorus Compounds; Reverse Transcriptase Inhibitors; Stavudine; Tenofovir; Tumor Cells, Cultured; Zalcitabine; Zidovudine

2002
The dangers of inferring treatment effects from observational data: a case study in HIV infection.
    Controlled clinical trials, 2002, Volume: 23, Issue:2

    Topics: Adult; Anti-HIV Agents; Data Interpretation, Statistical; Didanosine; Drug Therapy, Combination; HIV Infections; Humans; Observation; Randomized Controlled Trials as Topic; Selection Bias; Zalcitabine; Zidovudine

2002
[Drug combination therapy for children infected with HIV/AIDS--own experience].
    Przeglad epidemiologiczny, 2001, Volume: 55 Suppl 3

    Topics: Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Child; Child, Preschool; Didanosine; Drug Resistance, Viral; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; Humans; Infant; Lamivudine; Male; Nelfinavir; Poland; Reverse Transcriptase Inhibitors; Stavudine; Treatment Outcome; Viral Load; Zidovudine

2001
An ancient prevertebrate Na+-nucleoside cotransporter (hfCNT) from the Pacific hagfish (Eptatretus stouti).
    American journal of physiology. Cell physiology, 2002, Volume: 283, Issue:1

    Topics: Amino Acid Sequence; Animals; Anti-HIV Agents; Chimera; Cloning, Molecular; Didanosine; DNA, Complementary; Hagfishes; Kinetics; Molecular Sequence Data; Oocytes; Protein Isoforms; Recombinant Proteins; Symporters; Xenopus; Zalcitabine; Zidovudine

2002
Human immunodeficiency virus 1 strains resistant to nucleoside inhibitors of reverse transcriptase in isolates from the Czech Republic as monitored by line probe assay and nucleotide sequencing.
    Acta virologica, 2001, Volume: 45, Issue:5-6

    Topics: Base Sequence; Codon; Czech Republic; Didanosine; Drug Resistance, Viral; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Molecular Probe Techniques; Molecular Sequence Data; Mutation; Phylogeny; Prevalence; Reverse Transcriptase Inhibitors; Sequence Analysis, DNA; Zalcitabine; Zidovudine

2001
Molecular analysis of mutations at the HPRT and TK loci of human lymphoblastoid cells after combined treatments with 3'-azido-3'-deoxythymidine and 2',3'-dideoxyinosinedagger.
    Environmental and molecular mutagenesis, 2002, Volume: 39, Issue:4

    Topics: Anti-HIV Agents; B-Lymphocytes; Blotting, Southern; Cell Line; Didanosine; DNA; DNA Mutational Analysis; Drug Synergism; Gene Deletion; Genes, Reporter; Humans; Hypoxanthine Phosphoribosyltransferase; Mutagenicity Tests; Mutation; Point Mutation; Protein-Tyrosine Kinases; Reverse Transcriptase Polymerase Chain Reaction; Zidovudine

2002
[Mononucleosis syndrome with viro-immunologic parameters similar to those of a primary HIV-1 infection after interruption of highly effective anti-retroviral treatment].
    Anales de medicina interna (Madrid, Spain : 1984), 2002, Volume: 19, Issue:6

    Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4-CD8 Ratio; Depression; Didanosine; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Infectious Mononucleosis; Male; Reverse Transcriptase Inhibitors; Ritonavir; Stavudine; Treatment Refusal; Trimethoprim, Sulfamethoxazole Drug Combination; Viral Load; Viremia; Zalcitabine; Zidovudine

2002
When will once (-a day) be enough?
    The Hopkins HIV report : a bimonthly newsletter for healthcare providers, 2000, Volume: 12, Issue:3

    Topics: Acquired Immunodeficiency Syndrome; Alkynes; Antiretroviral Therapy, Highly Active; Benzoxazines; Cyclopropanes; Deoxycytidine; Didanosine; Emtricitabine; Humans; Hydroxyurea; Nevirapine; Oxazines; Reverse Transcriptase Inhibitors; Zidovudine

2000
[Cytomegalovirus retinitis after highly active antiretroviral therapy: a case report].
    Archivos de la Sociedad Espanola de Oftalmologia, 2002, Volume: 77, Issue:9

    Topics: Adult; AIDS-Related Opportunistic Infections; Antiretroviral Therapy, Highly Active; Antiviral Agents; CD4 Lymphocyte Count; Cytomegalovirus Retinitis; Didanosine; Ganciclovir; HIV Infections; HIV Protease Inhibitors; Humans; Lamivudine; Male; Retinal Hemorrhage; Reverse Transcriptase Inhibitors; Risk; Saquinavir; Stavudine; Substance Abuse, Intravenous; Zidovudine

2002
Macrophage protection by addition of glutathione (GSH)-loaded erythrocytes to AZT and DDI in a murine AIDS model.
    Antiviral research, 2002, Volume: 56, Issue:3

    Topics: Animals; Anti-HIV Agents; Didanosine; DNA, Viral; Drug Therapy, Combination; Erythrocytes; Female; Glutathione; Hypergammaglobulinemia; Lymphatic Diseases; Lymphocytes; Macrophages; Mice; Mice, Inbred C57BL; Murine Acquired Immunodeficiency Syndrome; Reverse Transcriptase Inhibitors; Splenomegaly; Zidovudine

2002
Determinations of zidovudine/didanosine/nevirapine and zidovudine/didanosine/ritonavir in human serum by micellar electrokinetic chromatography.
    Journal of pharmaceutical and biomedical analysis, 2002, Nov-07, Volume: 30, Issue:4

    Topics: Anti-HIV Agents; Chromatography, Micellar Electrokinetic Capillary; Didanosine; Humans; Nevirapine; Ritonavir; Zidovudine

2002
Repeated cycles of alternate administration of fludarabine and Zidovudine plus Didanosine inhibits murine AIDS and reduces proviral DNA content in lymph nodes to undetectable levels.
    Virology, 2002, Oct-25, Volume: 302, Issue:2

    Topics: Animals; Anti-HIV Agents; Antineoplastic Agents; Didanosine; DNA, Viral; Drug Administration Schedule; Drug Therapy, Combination; Female; Leukemia Virus, Murine; Lymph Nodes; Mice; Mice, Inbred C57BL; Murine Acquired Immunodeficiency Syndrome; Proviruses; Reverse Transcriptase Inhibitors; Treatment Outcome; Vidarabine; Zidovudine

2002
Multiple relapses of human cytomegalovirus retinitis during HAART in an AIDS patient with reconstitution of CD4+ T cell count in the absence of HCMV-specific CD4+ T cell response.
    Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2003, Volume: 26, Issue:1

    Topics: Adult; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Antiviral Agents; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; Cytomegalovirus Retinitis; Didanosine; Follow-Up Studies; Ganciclovir; HIV Protease Inhibitors; Humans; Lamivudine; Lymphocyte Activation; Male; Nevirapine; Recurrence; Reverse Transcriptase Inhibitors; Stavudine; Zidovudine

2003
New questions about an old combination--ddI + d4T.
    Project Inform perspective, 2003, Issue:35

    Topics: Didanosine; Drug Therapy, Combination; HIV Infections; Humans; Reverse Transcriptase Inhibitors; Stavudine; Zidovudine

2003
Acute hepatic failure and lactate acidosis associated with antiretroviral treatment for HIV.
    Wiener klinische Wochenschrift, 2003, Feb-28, Volume: 115, Issue:3-4

    Topics: Acidosis, Lactic; Acute Disease; Adult; Anti-HIV Agents; Biopsy; Critical Care; Didanosine; Drug Therapy, Combination; Female; Follow-Up Studies; HIV Infections; Humans; Liver; Liver Failure; Pancreatitis; Reverse Transcriptase Inhibitors; Stavudine; Time Factors; Tomography, X-Ray Computed; Treatment Outcome; Ultrasonography; Zidovudine

2003
Effects of hypokalemia and hypomagnesemia on zidovudine (AZT) and didanosine (ddI) nephrotoxicity in rats.
    Clinical nephrology, 2003, Volume: 59, Issue:4

    Topics: Acute Kidney Injury; Animals; Anti-HIV Agents; Didanosine; Diet; Disease Models, Animal; HIV Infections; Hypokalemia; Magnesium; Male; Rats; Rats, Wistar; Risk Factors; Zidovudine

2003
HIV-1 resistance profile of the novel nucleoside reverse transcriptase inhibitor beta-D-2',3'-dideoxy-2',3'-didehydro-5-fluorocytidine (Reverset).
    Antiviral chemistry & chemotherapy, 2003, Volume: 14, Issue:1

    Topics: Adenine; Anti-HIV Agents; Cell Line; Cytidine Triphosphate; Didanosine; Drug Resistance, Multiple, Viral; Genotype; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Mutation; Organophosphonates; Organophosphorus Compounds; Reverse Transcriptase Inhibitors; Species Specificity; Tenofovir; Transfection; Zalcitabine; Zidovudine

2003
Pathways for the emergence of multi-dideoxynucleoside-resistant HIV-1 variants.
    AIDS (London, England), 2003, May-23, Volume: 17, Issue:8

    Topics: Anti-HIV Agents; Didanosine; Dideoxynucleosides; Drug Resistance, Multiple, Viral; HIV Reverse Transcriptase; HIV-1; Humans; Mutation; Reverse Transcriptase Inhibitors; Virus Replication; Zidovudine

2003
[Observational study on the efficacy of the application of two classical regimens of triple antiretroviral therapy].
    Anales de medicina interna (Madrid, Spain : 1984), 2003, Volume: 20, Issue:5

    Topics: Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Cohort Studies; Didanosine; Drug Evaluation; Female; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Male; Retrospective Studies; Reverse Transcriptase Inhibitors; Stavudine; Time Factors; Treatment Outcome; Viral Load; Zidovudine

2003
Semiparametric regression analysis of longitudinal data with informative drop-outs.
    Biostatistics (Oxford, England), 2003, Volume: 4, Issue:3

    Topics: Child; Clinical Trials as Topic; Computer Simulation; Didanosine; HIV Infections; Humans; Longitudinal Studies; Models, Statistical; Numerical Analysis, Computer-Assisted; Patient Dropouts; Regression Analysis; Time Factors; Zidovudine

2003
Incorporating prior beliefs about selection bias into the analysis of randomized trials with missing outcomes.
    Biostatistics (Oxford, England), 2003, Volume: 4, Issue:4

    Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Bayes Theorem; CD4 Lymphocyte Count; Data Interpretation, Statistical; Didanosine; Double-Blind Method; Drug Therapy, Combination; Humans; Models, Statistical; Randomized Controlled Trials as Topic; Selection Bias; Statistics, Nonparametric; Treatment Outcome; Zidovudine

2003
Safety and efficacy of switching to alternative nucleoside analogues following symptomatic hyperlactatemia and lactic acidosis.
    AIDS (London, England), 2003, Nov-21, Volume: 17, Issue:17

    Topics: Acidosis, Lactic; Adult; Alanine Transaminase; Didanosine; Dideoxynucleosides; Drug Therapy, Combination; Female; HIV Infections; Humans; Lactates; Lamivudine; Male; Middle Aged; Reverse Transcriptase Inhibitors; Stavudine; Time Factors; Zidovudine

2003
HIV biological variability unveiled: frequent isolations and chimeric receptors reveal unprecedented variation of coreceptor use.
    AIDS (London, England), 2003, Dec-05, Volume: 17, Issue:18

    Topics: Adult; Anti-Retroviral Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Cell Line; Didanosine; Disease Progression; Evolution, Molecular; Genetic Variation; HIV Infections; HIV-1; Humans; Male; Phenotype; Receptors, CCR5; Receptors, CXCR4; Receptors, HIV; Recombinant Fusion Proteins; Virus Replication; Zidovudine

2003
Greater and more rapid depletion of mitochondrial DNA in blood of patients treated with dual (zidovudine+didanosine or zidovudine+zalcitabine) vs. single (zidovudine) nucleoside reverse transcriptase inhibitors.
    HIV medicine, 2004, Volume: 5, Issue:1

    Topics: Analysis of Variance; Anti-HIV Agents; Didanosine; DNA, Mitochondrial; Drug Combinations; HIV Infections; Humans; Mitochondrial Diseases; Reverse Transcriptase Inhibitors; Self-Sustained Sequence Replication; Sensitivity and Specificity; Zalcitabine; Zidovudine

2004
Genetic damage detected in CD-1 mouse pups exposed perinatally to 3'-azido-3'-deoxythymidine and dideoxyinosine via maternal dosing, nursing, and direct gavage.
    Environmental and molecular mutagenesis, 2004, Volume: 43, Issue:1

    Topics: Administration, Oral; Animals; Anti-HIV Agents; Didanosine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Erythrocytes; Female; Lactation; Male; Mice; Mice, Inbred Strains; Micronuclei, Chromosome-Defective; Micronucleus Tests; Mutagens; Pregnancy; Prenatal Exposure Delayed Effects; Time Factors; Zidovudine

2004
Efficacy and safety of ritonavir/indinavir 100/400 mg twice daily in combination with two nucleoside analogues in antiretroviral treatment-naive HIV-infected individuals.
    Antiviral therapy, 2003, Volume: 8, Issue:6

    Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Didanosine; Drug Administration Schedule; Drug Therapy, Combination; Female; HIV Infections; Humans; Indinavir; Lamivudine; Male; Middle Aged; Prospective Studies; Ritonavir; Stavudine; Zidovudine

2003
Pseudo-likelihood estimation for a marginal multivariate survival model.
    Statistics in medicine, 2004, Mar-30, Volume: 23, Issue:6

    Topics: Acquired Immunodeficiency Syndrome; Adoption; Antiviral Agents; Didanosine; Drug Therapy, Combination; Genetics, Population; Humans; Likelihood Functions; Models, Statistical; Multivariate Analysis; Survival Analysis; Zidovudine

2004
Interval-censored survival time data: confidence intervals for the non-parametric survivor function.
    Statistics in medicine, 2004, Apr-15, Volume: 23, Issue:7

    Topics: Antiviral Agents; Computer Simulation; Confidence Intervals; Data Interpretation, Statistical; Didanosine; HIV Infections; Humans; RNA, Viral; Survival Analysis; Zidovudine

2004
Frequency of Tk and Hprt lymphocyte mutants and bone marrow micronuclei in mice treated neonatally with zidovudine and didanosine.
    Mutagenesis, 2004, Volume: 19, Issue:4

    Topics: Animals; Animals, Newborn; Anti-HIV Agents; Bone Marrow Cells; Didanosine; Drug Interactions; Female; Hypoxanthine Phosphoribosyltransferase; Loss of Heterozygosity; Lymphocytes; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Micronucleus Tests; Mutagens; Thymidine Kinase; Zidovudine

2004
Nucleoside analogue use before and during highly active antiretroviral therapy and virus load rebound.
    The Journal of infectious diseases, 2004, Aug-15, Volume: 190, Issue:4

    Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Australia; Cohort Studies; Didanosine; Drug Administration Schedule; Europe; Female; HIV Infections; Humans; Lamivudine; Male; Proportional Hazards Models; Reverse Transcriptase Inhibitors; Stavudine; Time Factors; Viral Load; Zidovudine

2004
Phenotypic impact of HIV reverse transcriptase M184I/V mutations in combination with single thymidine analog mutations on nucleoside reverse transcriptase inhibitor resistance.
    AIDS (London, England), 2004, Aug-20, Volume: 18, Issue:12

    Topics: Adenine; Algorithms; Anti-HIV Agents; Databases, Genetic; Didanosine; Dideoxynucleosides; Drug Resistance, Multiple, Viral; HIV; HIV Infections; Humans; Mutation; Organophosphonates; Organophosphorus Compounds; Phenotype; Reverse Transcriptase Inhibitors; Stavudine; Tenofovir; Thymidine; Zalcitabine; Zidovudine

2004
Genetic damage detected in CD-1 mouse pups exposed perinatally to 3'-azido-3'-deoxythymidine or dideoxyinosine via maternal dosing, nursing, and direct gavage: II. Effects of the individual agents compared to combination treatment.
    Environmental and molecular mutagenesis, 2004, Volume: 44, Issue:4

    Topics: Analysis of Variance; Animals; Animals, Newborn; Anti-HIV Agents; Didanosine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Erythrocytes; Female; Male; Mice; Mice, Inbred Strains; Micronuclei, Chromosome-Defective; Micronucleus Tests; Pregnancy; Prenatal Exposure Delayed Effects; Zidovudine

2004
Hyperlactatemia in human immunodeficiency virus-uninfected infants who are exposed to antiretrovirals.
    Pediatrics, 2004, Volume: 114, Issue:5

    Topics: Alanine; Antiretroviral Therapy, Highly Active; Didanosine; Female; HIV Infections; HIV Seronegativity; Humans; Infant; Infant, Newborn; Infectious Disease Transmission, Vertical; Lactic Acid; Logistic Models; Male; Mitochondria; Pregnancy; Pregnancy Complications, Infectious; Prospective Studies; Reverse Transcriptase Inhibitors; Zidovudine

2004
Tenofovir: new indication. For first-line antiretroviral therapy: wait and see.
    Prescrire international, 2004, Volume: 13, Issue:73

    Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Controlled Clinical Trials as Topic; Didanosine; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Lamivudine; Reverse Transcriptase Inhibitors; Stavudine; Treatment Outcome; Zidovudine

2004
The HIV-1 nucleoside reverse transcriptase inhibitors stavudine and zidovudine alter adipocyte functions in vitro.
    AIDS (London, England), 2004, Nov-05, Volume: 18, Issue:16

    Topics: 3T3-L1 Cells; Adenine; Adipocytes; Animals; Apoptosis; Cell Differentiation; Didanosine; Dideoxynucleosides; HIV-1; HIV-Associated Lipodystrophy Syndrome; Lamivudine; Lipid Metabolism; Mice; Mitochondria; Organophosphonates; Reverse Transcriptase Inhibitors; Stavudine; Tenofovir; Zidovudine

2004
Simultaneous determination of the HIV nucleoside analogue reverse transcriptase inhibitors lamivudine, didanosine, stavudine, zidovudine and abacavir in human plasma by reversed phase high performance liquid chromatography.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2005, Feb-25, Volume: 816, Issue:1-2

    Topics: Anti-HIV Agents; Chromatography, High Pressure Liquid; Didanosine; Dideoxynucleosides; Drug Stability; HIV; HIV Infections; Humans; Lamivudine; Quality Control; Reproducibility of Results; Reverse Transcriptase Inhibitors; Sensitivity and Specificity; Spectrophotometry, Ultraviolet; Stavudine; Zidovudine

2005
Prolonged treatment interruption in chronic HIV infection: a new strategy?
    AIDS (London, England), 2005, Jan-28, Volume: 19, Issue:2

    Topics: Adult; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Chronic Disease; Cohort Studies; Didanosine; Drug Administration Schedule; Female; HIV Infections; HIV Protease Inhibitors; Humans; Male; Middle Aged; Reverse Transcriptase Inhibitors; RNA, Viral; Viral Load; Zidovudine

2005
Serum neopterin, an immune activation marker, independently predicts disease progression in advanced HIV-1 infection.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2005, Mar-15, Volume: 40, Issue:6

    Topics: Anti-HIV Agents; Biomarkers; CD4 Lymphocyte Count; Didanosine; Disease Progression; Dose-Response Relationship, Drug; Female; HIV Infections; Humans; Interferons; Interleukin-6; Male; Neopterin; Predictive Value of Tests; Risk Factors; Zidovudine

2005
Changes in mitochondrial RNA production in cells treated with nucleoside analogues.
    Antiviral therapy, 2005, Volume: 10, Issue:1

    Topics: Antiviral Agents; Cell Line; Didanosine; DNA, Mitochondrial; Humans; Polymerase Chain Reaction; Reverse Transcriptase Inhibitors; RNA; RNA, Mitochondrial; Stavudine; U937 Cells; Zidovudine

2005
Simple adjustments for randomized trials with nonrandomly missing or censored outcomes arising from informative covariates.
    Biostatistics (Oxford, England), 2006, Volume: 7, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; CD4 Lymphocyte Count; Didanosine; Humans; Likelihood Functions; Longitudinal Studies; Models, Statistical; Nevirapine; Proportional Hazards Models; Randomized Controlled Trials as Topic; Survival Analysis; Treatment Outcome; Zalcitabine; Zidovudine

2006
The L74V mutation in human immunodeficiency virus type 1 reverse transcriptase counteracts enhanced excision of zidovudine monophosphate associated with thymidine analog resistance mutations.
    Antimicrobial agents and chemotherapy, 2005, Volume: 49, Issue:7

    Topics: Adenosine Triphosphate; Anti-HIV Agents; Base Sequence; Didanosine; DNA Primers; Drug Resistance, Viral; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Molecular Sequence Data; Mutation; Reverse Transcriptase Inhibitors; Thymidine; Zidovudine

2005
Human immunodeficiency virus infection: personal experience in changes in head and neck manifestations due to recent antiretroviral therapies.
    Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale, 2005, Volume: 25, Issue:1

    Topics: Adult; Antiretroviral Therapy, Highly Active; CD4 Antigens; Didanosine; Drug Therapy, Combination; Female; Follow-Up Studies; HIV Infections; Humans; Incidence; Lymphoma, Non-Hodgkin; Male; Prevalence; Pseudomonas Infections; Sarcoma, Kaposi; Zidovudine

2005
The effect of long-term storage on measured plasma lactate concentrations and prospective lactate results from a multicenter trial of antiretroviral therapy.
    Clinical chemistry and laboratory medicine, 2005, Volume: 43, Issue:9

    Topics: Acidosis, Lactic; Anti-HIV Agents; Blood Preservation; Blood Specimen Collection; Didanosine; HIV Infections; Humans; Lactates; Lamivudine; Multicenter Studies as Topic; Oxalates; Randomized Controlled Trials as Topic; Reverse Transcriptase Inhibitors; Sodium Fluoride; Specimen Handling; Stavudine; Time Factors; Zidovudine

2005
Homo and heterodimers of ddI, d4T and AZT: influence of (5'-5') thiolcabonate-carbamate linkage on anti-HIV activity.
    Nucleosides, nucleotides & nucleic acids, 2005, Volume: 24, Issue:5-7

    Topics: Anti-HIV Agents; Antiviral Agents; Carbamates; Didanosine; Dimerization; HIV; HIV Infections; Models, Chemical; Molecular Conformation; Mutation; Stavudine; Sulfhydryl Compounds; Zidovudine

2005
Economic impact of antiretroviral therapy prescription decisions in the context of rapid scaling-up of access to treatment: lessons from Mexico.
    AIDS (London, England), 2006, Jan-02, Volume: 20, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Cyclopropanes; Didanosine; Drug Prescriptions; Health Care Costs; Health Services Accessibility; HIV Infections; HIV Protease Inhibitors; Humans; Mexico; Oxazines; Patient Compliance; Practice Guidelines as Topic; Saquinavir; Zidovudine

2006
In vitro mutagenicity studies of the antiretrovirals AZT, Didanosine, and 3TC and a plant antiviral extract Secomet-V derived from the Trifollium species.
    Annals of the New York Academy of Sciences, 2005, Volume: 1056

    Topics: Anti-HIV Agents; Antiviral Agents; Didanosine; Lamivudine; Mutagenicity Tests; Phytotherapy; Plant Extracts; Salmonella; Trifolium; Zidovudine

2005
A simplified weight-based method for pediatric drug dosing for zidovudine and didanosine in resource-limited settings.
    The Pediatric infectious disease journal, 2006, Volume: 25, Issue:1

    Topics: Adolescent; Anti-HIV Agents; Body Surface Area; Body Weight; Child; Child, Preschool; Didanosine; Dosage Forms; Female; HIV Infections; Humans; Infant; Male; Zidovudine

2006
Nucleotide excision repair and template-independent addition by HIV-1 reverse transcriptase in the presence of nucleocapsid protein.
    The Journal of biological chemistry, 2006, Apr-28, Volume: 281, Issue:17

    Topics: Didanosine; DNA Primers; DNA Repair; DNA Replication; DNA, Viral; Drug Resistance, Viral; HIV Reverse Transcriptase; HIV-1; Humans; Nucleocapsid Proteins; Recombinant Proteins; Reverse Transcriptase Inhibitors; RNA, Viral; Templates, Genetic; Virus Replication; Zidovudine

2006
[In vitro selection and phenotyping of HIV-1 mutants resistant to azidothymidine and didanosine].
    Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic], 2005, Volume: 50, Issue:5-6

    Topics: Didanosine; Drug Resistance, Viral; HIV-1; Mutation; Reverse Transcriptase Inhibitors; Stavudine; Thymidine; Zidovudine

2005
Virological response to HIV-1 nucleoside/nucleotide reverse transcriptase inhibitors-based, tenofovir DF-including regimens in the ANRS Aquitaine Cohort.
    Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2006, Volume: 36, Issue:2

    Topics: Adenine; Cohort Studies; Didanosine; Dideoxynucleosides; Drug Therapy, Combination; France; HIV Infections; HIV Reverse Transcriptase; HIV-1; Hospitals, University; Humans; Lamivudine; Mutation; Organophosphonates; Retrospective Studies; Reverse Transcriptase Inhibitors; Species Specificity; Tenofovir; Treatment Outcome; Viral Load; Zidovudine

2006
The K65R mutation in human immunodeficiency virus type 1 reverse transcriptase exhibits bidirectional phenotypic antagonism with thymidine analog mutations.
    Journal of virology, 2006, Volume: 80, Issue:10

    Topics: Adenine; Amino Acid Substitution; Anti-HIV Agents; Arginine; Didanosine; Dideoxynucleosides; Drug Resistance, Multiple, Viral; Genotype; HIV Reverse Transcriptase; HIV-1; Humans; Lysine; Organophosphonates; Phenotype; Point Mutation; Reverse Transcriptase Inhibitors; Tenofovir; Thymidine; Zalcitabine; Zidovudine

2006
In vitro cytotoxicity and mitochondrial toxicity of tenofovir alone and in combination with other antiretrovirals in human renal proximal tubule cells.
    Antimicrobial agents and chemotherapy, 2006, Volume: 50, Issue:11

    Topics: Adenine; Anti-HIV Agents; Cell Survival; Cells, Cultured; Didanosine; DNA, Mitochondrial; Drug Interactions; Electron Transport Complex IV; Humans; Kidney Tubules, Proximal; Lopinavir; Mitochondria; Organophosphonates; Pyrimidinones; Ritonavir; RNA; Tenofovir; Zidovudine

2006
Modulation of osteoclastogenesis induced by nucleoside reverse transcriptase inhibitors.
    AIDS research and human retroviruses, 2006, Volume: 22, Issue:11

    Topics: Alendronate; Animals; Apoptosis; Cell Differentiation; Didanosine; Humans; Leukocytes, Mononuclear; Male; Mice; Mice, Inbred C57BL; Osteoclasts; Osteoprotegerin; RANK Ligand; Reverse Transcriptase Inhibitors; Zidovudine

2006
[Sustained spontaneous remission of chronic hepatitis C coinfection in HIV].
    Enfermedades infecciosas y microbiologia clinica, 2007, Volume: 25, Issue:4

    Topics: Adult; Anti-HIV Agents; Didanosine; Female; Hepacivirus; Hepatitis C, Chronic; HIV Infections; Humans; Pregnancy; Pregnancy Complications, Infectious; Remission, Spontaneous; Viremia; Zidovudine

2007
Nodular regenerative hyperplasia: a new serious antiretroviral drugs side effect?
    AIDS (London, England), 2007, Jul-11, Volume: 21, Issue:11

    Topics: Anti-Retroviral Agents; Antiretroviral Therapy, Highly Active; Chemical and Drug Induced Liver Injury; Didanosine; Female; HIV Infections; HIV-1; Humans; Hyperplasia; Liver; Liver Diseases; Liver Regeneration; Middle Aged; Nevirapine; Zidovudine

2007
The reverse transcriptase 67N 70R 215Y genotype is the predominant TAM pathway associated with virologic failure among HIV type 1C-infected adults treated with ZDV/ddI-containing HAART in southern Africa.
    AIDS research and human retroviruses, 2007, Volume: 23, Issue:7

    Topics: Africa, Southern; Antiretroviral Therapy, Highly Active; Didanosine; Drug Resistance, Multiple, Viral; Evolution, Molecular; Female; Genotype; HIV Infections; HIV-1; Humans; Male; Molecular Sequence Data; Mutation; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Thymidine; Treatment Failure; Zidovudine

2007
Pharmacokinetics of coadministered ritonavir-boosted elvitegravir and zidovudine, didanosine, stavudine, or abacavir.
    Journal of acquired immune deficiency syndromes (1999), 2007, Oct-01, Volume: 46, Issue:2

    Topics: Adolescent; Adult; Confidence Intervals; Cross-Over Studies; Didanosine; Dideoxynucleosides; Drug Interactions; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Quinolones; Stavudine; Zidovudine

2007
Adaptation of antiretroviral therapy in human immunodeficiency virus infection with central nervous system involvement.
    Journal of neurovirology, 2008, Volume: 14, Issue:1

    Topics: Adenine; Adult; AIDS Dementia Complex; Alkynes; Anti-HIV Agents; Anticonvulsants; Antiretroviral Therapy, Highly Active; Atazanavir Sulfate; Benzoxazines; Cerebrospinal Fluid; Cyclopropanes; Didanosine; HIV-1; Humans; Indinavir; Lamivudine; Male; Nelfinavir; Nevirapine; Oligopeptides; Organophosphonates; Pyridines; Ritonavir; Seizures; Stavudine; Tenofovir; Viral Load; Virus Replication; Zidovudine

2008
Comparative analysis of genetic toxicity of AZT and ddI antiretrovirals in somatic cells of Drosophila melanogaster.
    Environmental and molecular mutagenesis, 2008, Volume: 49, Issue:4

    Topics: Animals; Anti-HIV Agents; Didanosine; Drosophila melanogaster; Female; Male; Mitosis; Mutagenicity Tests; Mutagens; Mutation; Recombination, Genetic; Reverse Transcriptase Inhibitors; Wings, Animal; Zidovudine

2008
[Evaluation of antiretroviral therapy in HIV-infected adults in the Department of Haematology, University Hospital of Brazzavllle, Congo].
    Bulletin de la Societe de pathologie exotique (1990), 2008, Volume: 101, Issue:2

    Topics: Adolescent; Adult; Aged; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; CD4 Lymphocyte Count; Congo; Cyclopropanes; Didanosine; Drug Evaluation; Drug Therapy, Combination; Female; Hematology; HIV Infections; Hospital Departments; Hospitals, University; Humans; Lamivudine; Male; Middle Aged; Nevirapine; Retrospective Studies; Stavudine; Treatment Outcome; Viral Load; Zidovudine

2008
The nucleoside reverse transcriptase inhibitors didanosine, lamivudine, stavudine and zidovudine show little effect on the virulence of Candida albicans in vitro.
    International journal of antimicrobial agents, 2008, Volume: 32, Issue:2

    Topics: Antifungal Agents; Biofilms; Candida albicans; Cell Adhesion; Cell Line; Didanosine; Humans; Lamivudine; Microbial Sensitivity Tests; Reverse Transcriptase Inhibitors; Stavudine; Virulence; Zidovudine

2008
[Screening of HIV-1 replication inhibitors by using pseudotyped virus system].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2008, Volume: 43, Issue:3

    Topics: Anti-HIV Agents; Didanosine; DNA Replication; Drug Evaluation, Preclinical; Genes, Reporter; HIV-1; Humans; Lamivudine; Pseudocowpox Virus; Tumor Cells, Cultured; Virus Replication; Zidovudine

2008
Noncirrhotic portal hypertension in patients with human immunodeficiency virus-1 infection.
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2008, Volume: 6, Issue:10

    Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Didanosine; Female; HIV Infections; HIV-1; Humans; Hypertension, Portal; Lamivudine; Male; Middle Aged; Risk Factors; Thrombophilia; Viral Load; Zidovudine

2008
Two-year outcomes of children on non-nucleoside reverse transcriptase inhibitor and protease inhibitor regimens in a South African pediatric antiretroviral program.
    The Pediatric infectious disease journal, 2008, Volume: 27, Issue:11

    Topics: Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Child; Child, Preschool; Cohort Studies; Didanosine; Female; HIV Infections; HIV Protease Inhibitors; Humans; Infant; Lamivudine; Lopinavir; Male; Multivariate Analysis; Pyrimidinones; Retrospective Studies; Reverse Transcriptase Inhibitors; Ritonavir; South Africa; Stavudine; Treatment Outcome; Zidovudine

2008
Effect of macrophage depletion on viral DNA rebound following antiretroviral therapy in a murine model of AIDS (MAIDS).
    Antiviral research, 2009, Volume: 81, Issue:2

    Topics: Animals; Anti-HIV Agents; Clodronic Acid; Didanosine; DNA, Viral; Female; Immunologic Factors; Leukocyte Reduction Procedures; Macrophages; Mice; Mice, Inbred C57BL; Murine Acquired Immunodeficiency Syndrome; Viral Load; Zidovudine

2009
Improvement of sensitivity and selectivity of high-performance liquid chromatography for anti-retroviral drugs (non-reverse transcriptase inhibitors) by diamond-electrode electrochemical and fluorescence detection.
    Journal of chromatography. A, 2009, Apr-10, Volume: 1216, Issue:15

    Topics: Anti-Retroviral Agents; Chromatography, High Pressure Liquid; Didanosine; Dideoxynucleosides; Electrochemical Techniques; Fluorescence; Humans; Lamivudine; Linear Models; Reproducibility of Results; Reverse Transcriptase Inhibitors; Sensitivity and Specificity; Water; Zidovudine

2009
Emergence of primary NNRTI resistance mutations without antiretroviral selective pressure in a HAART-treated child.
    PloS one, 2009, Volume: 4, Issue:3

    Topics: Adult; Antiretroviral Therapy, Highly Active; Didanosine; Drug Resistance, Multiple, Viral; Female; HIV Infections; HIV-1; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Mutation, Missense; Nelfinavir; Phylogeny; Point Mutation; Pregnancy; Pregnancy Complications, Infectious; Selection, Genetic; Zidovudine

2009
Permeation of four oral drugs through human intestinal mucosa.
    AAPS PharmSciTech, 2009, Volume: 10, Issue:1

    Topics: Administration, Oral; Adult; Didanosine; Diffusion; Drug Evaluation, Preclinical; Enalapril; Female; Humans; In Vitro Techniques; Intestinal Absorption; Intestinal Mucosa; Jejunum; Kinetics; Male; Middle Aged; Permeability; Propranolol; Reproducibility of Results; Solubility; Zidovudine

2009
WR1065 mitigates AZT-ddI-induced mutagenesis and inhibits viral replication.
    Environmental and molecular mutagenesis, 2009, Volume: 50, Issue:6

    Topics: Adenoviridae; Cell Line; Cytoplasm; Didanosine; Dideoxynucleotides; Dose-Response Relationship, Drug; HIV Core Protein p24; HIV-1; Humans; Hypoxanthine Phosphoribosyltransferase; Influenza A virus; Influenza B virus; Intracellular Space; Lymphocytes; Mercaptoethylamines; Mutagenesis; Mutation; Phytohemagglutinins; Serotyping; Time Factors; Virus Replication; Zidovudine

2009
Mitochondrial DNA depletion in rat liver induced by fosalvudine tidoxil, a novel nucleoside reverse transcriptase inhibitor prodrug.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:7

    Topics: Animals; Didanosine; DNA, Mitochondrial; Lipids; Liver; Male; Polymerase Chain Reaction; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Inhibitors; Zidovudine

2009
High rates of survival, immune reconstitution, and virologic suppression on second-line antiretroviral therapy in South Africa.
    Journal of acquired immune deficiency syndromes (1999), 2010, Apr-01, Volume: 53, Issue:4

    Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Didanosine; Female; HIV Infections; Humans; Lopinavir; Male; Pyrimidinones; Ritonavir; South Africa; Survival Analysis; Treatment Outcome; Viral Load; Zidovudine

2010
Efficacy and safety of 1-month postpartum zidovudine-didanosine to prevent HIV-resistance mutations after intrapartum single-dose nevirapine.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2010, Mar-15, Volume: 50, Issue:6

    Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Didanosine; Drug Resistance, Viral; Female; HIV Infections; HIV-1; Humans; Ligase Chain Reaction; Mutation, Missense; Nevirapine; Postpartum Period; Pregnancy; RNA, Viral; Sequence Analysis, DNA; Viral Load; Young Adult; Zidovudine

2010
Another milestone in minimizing risks to mothers exposed to single-dose nevirapine for prevention of vertical transmission of HIV-1 to infants: what next?
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2010, Mar-15, Volume: 50, Issue:6

    Topics: Anti-HIV Agents; Didanosine; Drug Resistance, Viral; Female; HIV Infections; HIV-1; Humans; Infant; Infant, Newborn; Mutation, Missense; Nevirapine; Pregnancy; Zidovudine

2010
A weighted combination of pseudo-likelihood estimators for longitudinal binary data subject to non-ignorable non-monotone missingness.
    Statistics in medicine, 2010, Jun-30, Volume: 29, Issue:14

    Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; CD4 Lymphocyte Count; Clinical Trials, Phase III as Topic; Computer Simulation; Didanosine; Double-Blind Method; Humans; Longitudinal Studies; Models, Statistical; Zidovudine

2010
Evaluation of HIV protease and nucleoside reverse transcriptase inhibitors on proliferation, necrosis, apoptosis in intestinal epithelial cells and electrolyte and water transport and epithelial barrier function in mice.
    BMC gastroenterology, 2010, Aug-11, Volume: 10

    Topics: Animals; Anti-Retroviral Agents; Apoptosis; Body Weight; Cell Membrane Permeability; Cell Proliferation; Didanosine; HIV Protease Inhibitors; Indinavir; Intestinal Absorption; Intestinal Mucosa; Male; Mice; Models, Animal; Necrosis; Nelfinavir; Reverse Transcriptase Inhibitors; Survival Rate; Water-Electrolyte Balance; Zidovudine

2010
Progressive mitochondrial compromise in brains and livers of primates exposed in utero to nucleoside reverse transcriptase inhibitors (NRTIs).
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:1

    Topics: Animals; Animals, Newborn; Cerebral Cortex; Didanosine; Disease Models, Animal; DNA, Mitochondrial; Drug Therapy, Combination; Erythrocebus patas; Female; Lamivudine; Maternal Exposure; Mitochondria, Liver; Oxidative Phosphorylation; Pregnancy; Reverse Transcriptase Inhibitors; Stavudine; Zidovudine

2010
Genotypic and phenotypic cross-drug resistance of harboring drug-resistant HIV type 1 subtype B' strains from former blood donors in central Chinese provinces.
    AIDS research and human retroviruses, 2010, Volume: 26, Issue:9

    Topics: Adult; Anti-HIV Agents; Blood Donors; China; Didanosine; Drug Resistance, Multiple, Viral; Female; Genotype; HIV Infections; HIV-1; Humans; Lamivudine; Male; Middle Aged; Mutation; Phenotype; pol Gene Products, Human Immunodeficiency Virus; RNA, Viral; Sequence Analysis, RNA; Stavudine; Zidovudine

2010
Combination anti-HIV therapy with the self-assemblies of an asymmetric bolaamphiphilic zidovudine/didanosine prodrug.
    Molecular pharmaceutics, 2011, Jun-06, Volume: 8, Issue:3

    Topics: Animals; Anti-HIV Agents; Cell Line; Cell Survival; Chromatography, High Pressure Liquid; Didanosine; HIV Infections; Humans; Mice; Prodrugs; Zidovudine

2011
Common inherited mitochondrial DNA mutations and nucleoside reverse transcriptase inhibitor-induced severe hyperlactataemia in HIV-infected adults: an exploratory study.
    Antiviral therapy, 2012, Volume: 17, Issue:2

    Topics: Acidosis, Lactic; Adult; Anti-HIV Agents; Black People; Case-Control Studies; Didanosine; DNA, Mitochondrial; Female; HIV Infections; Humans; Leukocytes, Mononuclear; Male; Middle Aged; Mitochondria; Mutation; Polymorphism, Single Nucleotide; Reverse Transcriptase Inhibitors; Sequence Deletion; Stavudine; White People; Zidovudine

2012
The combined use of known antiviral reverse transcriptase inhibitors AZT and DDI induce anticancer effects at low concentrations.
    Neoplasia (New York, N.Y.), 2012, Volume: 14, Issue:1

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Blotting, Southern; Cell Line, Tumor; Didanosine; Fluorescent Antibody Technique; Humans; Immunohistochemistry; In Situ Hybridization, Fluorescence; Mice; Mice, Nude; Neoplasms, Experimental; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Inhibitors; Telomere; Telomere Shortening; Xenograft Model Antitumor Assays; Zidovudine

2012
Azidothymidine and other chain terminators are mutagenic for template-switch-generated genetic mutations.
    Proceedings of the National Academy of Sciences of the United States of America, 2012, Apr-17, Volume: 109, Issue:16

    Topics: Anti-HIV Agents; Base Sequence; Didanosine; DNA, Bacterial; Escherichia coli; Models, Genetic; Mutagens; Mutation; Stavudine; Templates, Genetic; Zidovudine

2012
In vitro and ex vivo inhibition of human telomerase by anti-HIV nucleoside reverse transcriptase inhibitors (NRTIs) but not by non-NRTIs.
    PloS one, 2012, Volume: 7, Issue:11

    Topics: Adenine; Alkynes; Anti-HIV Agents; Benzoxazines; Cell Line; Cyclopropanes; Didanosine; Dideoxynucleosides; DNA Primers; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Nevirapine; Organophosphonates; Reverse Transcriptase Inhibitors; Stavudine; Telomerase; Tenofovir; Zidovudine

2012
Comparative analysis of genetic toxicity of antiretroviral combinations in somatic cells of Drosophila melanogaster.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2013, Volume: 53

    Topics: Animals; Anti-HIV Agents; Antiviral Agents; CD4 Lymphocyte Count; Didanosine; DNA Damage; Dose-Response Relationship, Drug; Drosophila melanogaster; Drug Combinations; Female; Lamivudine; Male; Mitosis; Mutation; Recombinant Proteins; Wings, Animal; Zidovudine

2013
Didanosine-associated retinal toxicity in adults infected with human immunodeficiency virus.
    JAMA ophthalmology, 2013, Volume: 131, Issue:2

    Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Corneal Dystrophies, Hereditary; Didanosine; Electroretinography; HIV Infections; Humans; Male; Middle Aged; Retina; Visual Acuity; Zidovudine

2013
Vitamin D attenuates nucleoside reverse transcriptase inhibitor induced human skeletal muscle mitochondria DNA depletion.
    AIDS (London, England), 2013, Jun-01, Volume: 27, Issue:9

    Topics: Anti-HIV Agents; Calcitriol; Didanosine; DNA, Mitochondrial; Drug Therapy, Combination; Female; HIV Reverse Transcriptase; Humans; Infant; Lamivudine; Mitochondria, Muscle; Muscle Fibers, Skeletal; Muscle, Skeletal; Myoblasts; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Inhibitors; Stavudine; Vitamins; Zidovudine

2013
Long-term exposure of mice to nucleoside analogues disrupts mitochondrial DNA maintenance in cortical neurons.
    PloS one, 2014, Volume: 9, Issue:1

    Topics: Animals; Antimetabolites; Cells, Cultured; Cerebral Cortex; Didanosine; DNA, Mitochondrial; Lamivudine; Liver; Mice; Mitochondria; Muscle, Skeletal; Neurons; Stavudine; Zidovudine

2014
Tempol protects cardiomyocytes from nucleoside reverse transcriptase inhibitor-induced mitochondrial toxicity.
    Toxicological sciences : an official journal of the Society of Toxicology, 2014, Volume: 139, Issue:1

    Topics: Animals; Cell Line; Cyclic N-Oxides; Didanosine; Microscopy, Electron; Mitochondria; Myocytes, Cardiac; Rats; Reverse Transcriptase Inhibitors; Spin Labels; Superoxides; Zidovudine

2014
Caenorhabditis elegans as a Model System for Studying Drug Induced Mitochondrial Toxicity.
    PloS one, 2015, Volume: 10, Issue:5

    Topics: Animals; Anti-HIV Agents; Caenorhabditis elegans; Didanosine; Dideoxynucleosides; DNA-Directed DNA Polymerase; DNA, Mitochondrial; Drug Evaluation; Humans; Mitochondria; Mitochondrial Proteins; Models, Biological; Oxygen Consumption; Reverse Transcriptase Inhibitors; Stavudine; Ubiquinone; Zalcitabine; Zidovudine

2015
Mitochondrial DNA D-loop AG/TC transition mutation in cortical neurons of mice after long-term exposure to nucleoside analogues.
    Journal of neurovirology, 2015, Volume: 21, Issue:5

    Topics: Animals; Cerebral Cortex; Didanosine; DNA, Mitochondrial; Lamivudine; Laser Capture Microdissection; Mice; Mice, Inbred BALB C; Mutation; Neurons; Polymerase Chain Reaction; Reverse Transcriptase Inhibitors; Stavudine; Zidovudine

2015
Prevalence of drug resistance mutations in HAART patients infected with HIV-1 CRF06_cpx in Estonia.
    Journal of medical virology, 2016, Volume: 88, Issue:3

    Topics: Adult; Alkynes; Antiretroviral Therapy, Highly Active; Benzoxazines; Cyclopropanes; Didanosine; Dideoxynucleosides; Drug Resistance, Viral; Estonia; HIV Infections; HIV-1; Humans; Lamivudine; Male; Mutation; Prevalence; Reverse Transcriptase Inhibitors; Zidovudine

2016
Structural Insights into HIV Reverse Transcriptase Mutations Q151M and Q151M Complex That Confer Multinucleoside Drug Resistance.
    Antimicrobial agents and chemotherapy, 2017, Volume: 61, Issue:6

    Topics: Anti-HIV Agents; Crystallography, X-Ray; Didanosine; DNA-Binding Proteins; Drug Resistance, Viral; Gene Products, pol; Hepatitis B virus; HIV Reverse Transcriptase; HIV-1; Humans; Mutation; Protein Conformation; Protein Structure, Quaternary; Reverse Transcriptase Inhibitors; Zalcitabine; Zidovudine

2017
A Lower Baseline CD4/CD8 T-Cell Ratio Is Independently Associated with Immunodiscordant Response to Antiretroviral Therapy in HIV-Infected Subjects.
    Antimicrobial agents and chemotherapy, 2017, Volume: 61, Issue:8

    Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Biomarkers; CD4-CD8 Ratio; CD8-Positive T-Lymphocytes; Cell Survival; Didanosine; Female; HIV Infections; Humans; Male; Middle Aged; Receptors, CXCR4; Stavudine; T-Lymphocytes, Regulatory; Viral Load; Zalcitabine; Zidovudine

2017
Risk of cancer in children exposed to antiretroviral nucleoside analogues in utero: The french experience.
    Environmental and molecular mutagenesis, 2019, Volume: 60, Issue:5

    Topics: Adolescent; Anti-HIV Agents; Child; Child, Preschool; Didanosine; Female; HIV Infections; Humans; Incidence; Infant; Infant, Newborn; Male; Maternal Exposure; Maternal-Fetal Exchange; Neoplasms; Nucleosides; Pregnancy; Prenatal Exposure Delayed Effects; Prospective Studies; Reverse Transcriptase Inhibitors; Risk; Surveys and Questionnaires; Zidovudine

2019
Evaluation of a Library of FDA-Approved Drugs for Their Ability To Potentiate Antibiotics against Multidrug-Resistant Gram-Negative Pathogens.
    Antimicrobial agents and chemotherapy, 2019, Volume: 63, Issue:8

    Topics: Anti-Bacterial Agents; Didanosine; Drug Resistance, Multiple, Bacterial; Ethanolamines; Floxuridine; Gram-Negative Bacteria; Microbial Sensitivity Tests; Mitoxantrone; Zidovudine

2019
Sustainable Protocol for the Synthesis of 2',3'-Dideoxynucleoside and 2',3'-Didehydro-2',3'-dideoxynucleoside Derivatives.
    Molecules (Basel, Switzerland), 2022, Jun-21, Volume: 27, Issue:13

    Topics: Anti-HIV Agents; Didanosine; Dideoxynucleosides; Stavudine; Zalcitabine; Zidovudine

2022
The antiretroviral agents azidothymidine, stavudine, and didanosine have the identical mutational fingerprint in the rpoB region of Escherichia coli.
    Environmental and molecular mutagenesis, 2022, Volume: 63, Issue:7

    Topics: Anti-HIV Agents; Anti-Retroviral Agents; Didanosine; DNA-Directed RNA Polymerases; Escherichia coli; Escherichia coli Proteins; HIV Reverse Transcriptase; Mutation; Stavudine; Zidovudine

2022