Page last updated: 2024-08-23

zidovudine and cytarabine

zidovudine has been researched along with cytarabine in 42 studies

Research

Studies (42)

TimeframeStudies, this research(%)All Research%
pre-19903 (7.14)18.7374
1990's16 (38.10)18.2507
2000's13 (30.95)29.6817
2010's10 (23.81)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Corbett, TH; Court, BA; Kessel, D; Phadtare, S; Renis, HE; Zimlicka, J1
Chen, R; Nelson, JA1
Alam, N; Hong, J; Im, KS; Jung, JH; Lee, CK; Li, F; Liu, Y; Wang, W1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Björck, L; Clausen, AR; Piskur, J; Sandrini, MP; Shannon, O1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Celewicz, L; Czarnecka, A; Hoffmann, M; Hładoń, B; Jóźwiak, A; Laskowska, H; Olejnik, A; Ruszkowski, P1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Celewicz, L; Gajecka, M; Klich, K; Kubicka, MM; Przybylski, P; Pyta, K; Ruszkowski, P1
Celewicz, L; Kleczewska, N; Liberska, J; Ruszkowski, P; Singh, A; Trznadel, R1
Brett, CM; Giacomini, KM; Hui, AC; Wu, X; Yuan, G1
Ashida, N; Baba, M; Ikeda, T; Machida, H; Sakata, S; Shigeta, S1
Agur, Z; Cojocaru, L1
Chen, CH; Cheng, YC; Vazquez-Padua, M1
Matsuda, A; Sasaki, T; Ueda, T; Yasuoka, J1
ten Kate, RW; Wijermans, PW1
Broder, S; Mitsuya, H; Webb, TR1
Chisaka, O; Matsubara, K; Nagahata, T; Tsurimoto, T; Ueda, K1
Munch-Petersen, B1
Kim, B; Loeb, LA1
Fong, IW; Toma, E1
Oh-hara, T; Tsuruo, T; Yusa, K1
Holý, A; Merta, A; Stĕtina, R; Votruba, I1
Kane, D; Keating, S; McCann, S; Mulcahy, F1
Groothuis, D; Levy, RM; Schalgeter, K; Ward, S1
Einat, M; Fabian, I; Nagler, A; Toren, A1
Hou, J; Major, EO1
Cinatl, J; Doerr, HW; Driever, PH; Gröschel, B; Kabickova, H; Kornhuber, B; Kotchetkov, R; Schwabe, D1
Knecht, W; Munch-Petersen, B; Piskur, J1
Horowitz, D; King, AG1
Amici, A; Emanuelli, M; Magni, G; Raffaelli, N; Ruggieri, S1
Agarwal, RP; Fernandez, M; Han, T; Sarkar, M2
Eklund, H; Mikkelsen, NE; Munch-Petersen, B1
Cheng, J; Chou, TF; Ghosh, B; Liu, B; Wagner, CR; Zhou, X1
Dalla Rosa, I; Dexheimer, TS; Gmeiner, WH; Huang, SY; Murai, J; Naumova, A; Pommier, Y1
Assaraf, YG; Berman, B; Levin, M; Stark, M1

Reviews

2 review(s) available for zidovudine and cytarabine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
The management of acute myeloid leukaemia (AML) in human immunodeficiency virus (HIV) infection: a case report and review.
    International journal of STD & AIDS, 1997, Volume: 8, Issue:4

    Topics: Adult; Anti-HIV Agents; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Cytarabine; Daunorubicin; Drug Therapy, Combination; HIV Infections; Humans; Leukemia, Myeloid, Acute; Male; Thioguanine; Zidovudine

1997

Other Studies

40 other study(ies) available for zidovudine and cytarabine

ArticleYear
Unsaturated and carbocyclic nucleoside analogues: synthesis, antitumor, and antiviral activity.
    Journal of medicinal chemistry, 1991, Volume: 34, Issue:1

    Topics: Adenosine Deaminase; Animals; Antimetabolites, Antineoplastic; Antiviral Agents; Cell Line; Cell Survival; Drug Screening Assays, Antitumor; Friend murine leukemia virus; HIV-1; HIV-2; Humans; Indicators and Reagents; Leukemia L1210; Mice; Molecular Structure; Nucleosides; Rauscher Virus; Structure-Activity Relationship

1991
Role of organic cation transporters in the renal secretion of nucleosides.
    Biochemical pharmacology, 2000, Jul-15, Volume: 60, Issue:2

    Topics: Animals; Carrier Proteins; Humans; Ion Transport; Kidney; Membrane Proteins; Mice; Nucleosides; Oocytes; Organic Cation Transport Proteins; Organic Cation Transporter 1; Organic Cation Transporter 2; Rats; Recombinant Proteins; Tetraethylammonium; Tubercidin; Xenopus laevis

2000
New saponins from the starfish Certonardoa semiregularis.
    Journal of natural products, 2002, Volume: 65, Issue:11

    Topics: Animals; Antineoplastic Agents; Antiviral Agents; Artemia; HeLa Cells; Humans; Korea; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Saponins; Starfish; Stereoisomerism; Steroids

2002
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Deoxyribonucleoside kinases activate nucleoside antibiotics in severely pathogenic bacteria.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:8

    Topics: Animals; Anti-Bacterial Agents; Deoxycytidine; Female; Gemcitabine; Humans; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Molecular Sequence Data; Nucleosides; Phosphotransferases (Alcohol Group Acceptor); Staphylococcal Infections; Staphylococcus aureus; Streptococcal Infections; Streptococcus pyogenes

2007
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Synthesis and anticancer activity of 5'-chloromethylphosphonates of 3'-azido-3'-deoxythymidine (AZT).
    Bioorganic & medicinal chemistry, 2011, Nov-01, Volume: 19, Issue:21

    Topics: Antineoplastic Agents; Biological Transport; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Female; Humans; Magnetic Resonance Spectroscopy; Molecular Structure; Mouth Neoplasms; Organophosphonates; Prodrugs; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Zidovudine

2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Synthesis, Antibacterial, and Anticancer Evaluation of Novel Spiramycin-Like Conjugates Containing C(5) Triazole Arm.
    Journal of medicinal chemistry, 2016, 09-08, Volume: 59, Issue:17

    Topics: Anti-Bacterial Agents; Antineoplastic Agents; Cell Line, Tumor; Cycloaddition Reaction; Drug Screening Assays, Antitumor; Gram-Positive Bacteria; Humans; Microbial Sensitivity Tests; Models, Molecular; Solubility; Spiramycin; Structure-Activity Relationship; Thermodynamics; Triazoles

2016
Synthesis and in vitro anticancer activity of new gemcitabine-nucleoside analogue dimers containing methyltriazole or ester-methyltriazole linker.
    Bioorganic & medicinal chemistry letters, 2019, 09-15, Volume: 29, Issue:18

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Click Chemistry; Deoxycytidine; Dimerization; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Esters; Gemcitabine; Humans; Molecular Structure; Nucleosides; Structure-Activity Relationship; Triazoles

2019
Sodium-dependent nucleoside transport in choroid plexus from rabbit. Evidence for a single transporter for purine and pyrimidine nucleosides.
    The Journal of biological chemistry, 1992, May-05, Volume: 267, Issue:13

    Topics: Adenosine Triphosphate; Animals; Carrier Proteins; Choroid Plexus; Cytarabine; Didanosine; Membrane Proteins; Nucleoside Transport Proteins; Purine Nucleosides; Pyrimidine Nucleosides; Rabbits; Sodium; Substrate Specificity; Zalcitabine; Zidovudine

1992
In vitro drug combination of 1-beta-D-arabinofuranosyl-E-5-(2-bromovinyl)uracil with anti-human immunodeficiency virus or anticancer nucleosides.
    Antimicrobial agents and chemotherapy, 1992, Volume: 36, Issue:1

    Topics: Antiviral Agents; Arabinofuranosyluracil; Bromouracil; Cytarabine; Drug Combinations; Floxuridine; Fluorouracil; Herpesvirus 3, Human; HIV-1; Humans; Zidovudine

1992
A theoretical analysis of interval drug dosing for cell-cycle-phase-specific drugs.
    Mathematical biosciences, 1992, Volume: 109, Issue:1

    Topics: Animals; Cell Cycle; Cell Survival; Cytarabine; Humans; Mathematics; Models, Biological; Pharmaceutical Preparations; Zidovudine

1992
Effect of anti-human immunodeficiency virus nucleoside analogs on mitochondrial DNA and its implication for delayed toxicity.
    Molecular pharmacology, 1991, Volume: 39, Issue:5

    Topics: Antiviral Agents; Cell Line; Cytarabine; Didanosine; Dideoxynucleosides; DNA, Mitochondrial; HIV; Humans; Lymphocyte Activation; Nucleosides; Stavudine; T-Lymphocytes; Zalcitabine; Zidovudine

1991
Nucleosides and nucleotides. 95. Improved synthesis of 1-(2-azido-2-deoxy-beta-D-arabinofuranosyl)cytosine (cytarazid) and -thymine. Inhibitory spectrum of cytarazid on the growth of various human tumor cells in vitro.
    Journal of medicinal chemistry, 1991, Volume: 34, Issue:3

    Topics: Adenocarcinoma; Antineoplastic Agents; Chemical Phenomena; Chemistry; Cytarabine; Humans; Molecular Structure; Nucleic Acid Synthesis Inhibitors; Stomach Neoplasms; Tumor Cells, Cultured; Zidovudine

1991
Successful chemotherapy for acute myeloid leucaemia in HIV-infected patients.
    European journal of haematology, 1990, Volume: 44, Issue:2

    Topics: CD4 Antigens; Cytarabine; HIV Antibodies; HIV Infections; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Zidovudine

1990
1-(2,3-Anhydro-beta-D-lyxofuranosyl)cytosine derivatives as potential inhibitors of the human immunodeficiency virus.
    Journal of medicinal chemistry, 1988, Volume: 31, Issue:7

    Topics: Ancitabine; Chemical Phenomena; Chemistry; Cytarabine; Cytidine; HIV; Magnetic Resonance Spectroscopy; Mass Spectrometry; Thymidine; Uracil; Zidovudine

1988
An in vitro system for screening anti-hepatitis B virus drugs.
    Virology, 1989, Volume: 169, Issue:1

    Topics: Acyclovir; Adenine; Antiviral Agents; Blotting, Southern; Carcinoma, Hepatocellular; Cytarabine; Dideoxyadenosine; Dideoxynucleosides; DNA Replication; DNA, Viral; Hepatitis B virus; Humans; Interferons; Liver Neoplasms; Tumor Cells, Cultured; Vidarabine; Virus Replication; Zalcitabine; Zidovudine

1989
Azidothymidine inhibits mitogen stimulated growth and DNA-repair in human peripheral lymphocytes.
    Biochemical and biophysical research communications, 1988, Dec-30, Volume: 157, Issue:3

    Topics: Adolescent; Adult; Cell Division; Cytarabine; DNA Damage; DNA Repair; Female; Humans; Lymphocytes; Male; Middle Aged; Phytohemagglutinins; Ultraviolet Rays; Zidovudine

1988
A screen in Escherichia coli for nucleoside analogs that target human immunodeficiency virus (HIV) reverse transcriptase: coexpression of HIV reverse transcriptase and herpes simplex virus thymidine kinase.
    Journal of virology, 1995, Volume: 69, Issue:10

    Topics: Antiviral Agents; Cloning, Molecular; Cytarabine; DNA Polymerase I; Drug Evaluation, Preclinical; Escherichia coli; Gene Expression; HIV; Kinetics; Phosphorylation; Recombinant Proteins; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Simplexvirus; Thymidine Kinase; Zalcitabine; Zidovudine

1995
The natural history of progressive multifocal leukoencephalopathy in patients with AIDS. Canadian PML Study Group.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1995, Volume: 20, Issue:5

    Topics: Acquired Immunodeficiency Syndrome; Adult; Aged; CD4 Lymphocyte Count; Cytarabine; Female; Humans; Leukoencephalopathy, Progressive Multifocal; Male; Middle Aged; Zidovudine

1995
Induction of resistance to 1-beta-D-arabinofuranosylcytosine in human H9 cell line by simian immunodeficiency virus.
    Biochemical and biophysical research communications, 1995, Jan-17, Volume: 206, Issue:2

    Topics: Cell Division; Cell Line; Cell Survival; Cytarabine; Cytidine Deaminase; Drug Resistance; Fluorouracil; Humans; Leukemia-Lymphoma, Adult T-Cell; Mercaptopurine; Simian Immunodeficiency Virus; Tetrahydrouridine; Tumor Cells, Cultured; Vidarabine; Zalcitabine; Zidovudine

1995
The effect of purine phosphonomethoxyalkyl derivatives on DNA synthesis in CHO Chinese hamster cells.
    Neoplasma, 1993, Volume: 40, Issue:6

    Topics: Adenine; Animals; Antiviral Agents; CHO Cells; Cricetinae; Cricetulus; Cytarabine; DNA Damage; DNA Replication; Dose-Response Relationship, Drug; Guanine; Organophosphonates; Organophosphorus Compounds; Zidovudine

1993
Alternative delivery systems for antiviral nucleosides and antisense oligonucleotides to the brain.
    Journal of neurovirology, 1997, Volume: 3 Suppl 1

    Topics: Animals; Antiviral Agents; Brain; Carbon Radioisotopes; Caudate Nucleus; Cerebral Ventricles; Cytarabine; Drug Carriers; Functional Laterality; Infusions, Intravenous; Infusions, Parenteral; Mice; Mice, Inbred Strains; Oligonucleotides, Antisense; Organ Specificity; Rats; Rats, Sprague-Dawley; Sulfur Radioisotopes; Thionucleotides; Zidovudine

1997
Human umbilical cord blood myeloid progenitor cells are relatively chemoresistant: a potential model for autologous transplantations in HIV-infected newborns.
    American journal of hematology, 1997, Volume: 56, Issue:3

    Topics: Antiviral Agents; Bone Marrow Cells; Cell Division; Cells, Cultured; Colony-Forming Units Assay; Cytarabine; Drug Resistance; Female; Fetal Blood; Flow Cytometry; Hematopoietic Stem Cell Transplantation; Hematopoietic Stem Cells; HIV Infections; Humans; Infant, Newborn; Interferon-alpha; Models, Biological; Phenanthrolines; Transplantation, Autologous; Zidovudine

1997
The efficacy of nucleoside analogs against JC virus multiplication in a persistently infected human fetal brain cell line.
    Journal of neurovirology, 1998, Volume: 4, Issue:4

    Topics: Anti-HIV Agents; Antiviral Agents; Brain; Cells, Cultured; Cidofovir; Cytarabine; Cytosine; DNA, Viral; Enzyme Inhibitors; Fetus; Humans; JC Virus; Neurons; Nucleosides; Organophosphonates; Organophosphorus Compounds; Papillomavirus Infections; Topotecan; Tumor Virus Infections; Virus Replication; Zidovudine

1998
Azidothymidine resistance of H9 human T-cell lymphoma cells is associated with decreased sensitivity to antitumor agents and inhibition of apoptosis.
    International journal of molecular medicine, 1998, Volume: 2, Issue:6

    Topics: Anti-HIV Agents; Antimetabolites; Antineoplastic Agents; Apoptosis; Cytarabine; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Humans; Lymphoma, T-Cell; Tumor Cells, Cultured; Zalcitabine; Zidovudine

1998
Identification of residues involved in the specificity and regulation of the highly efficient multisubstrate deoxyribonucleoside kinase from Drosophila melanogaster.
    Journal of molecular biology, 2000, Aug-25, Volume: 301, Issue:4

    Topics: Animals; Cytarabine; Dideoxyadenosine; Directed Molecular Evolution; Drosophila melanogaster; Enzyme Activation; Feedback; Inhibitory Concentration 50; Kinetics; Mutation; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Polymerase Chain Reaction; Substrate Specificity; Thymidine; Thymine Nucleotides; Zalcitabine; Zidovudine

2000
Colorimetric determination of inhibition of hematopoietic progenitor cells in soft agar.
    Journal of immunological methods, 2000, Oct-20, Volume: 244, Issue:1-2

    Topics: Animals; Antimetabolites; Antimetabolites, Antineoplastic; Antiviral Agents; Colony-Forming Units Assay; Colony-Stimulating Factors; Colorimetry; Coloring Agents; Cytarabine; Cytokines; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Female; Fluorouracil; Ganciclovir; Growth Inhibitors; Hematopoietic Stem Cells; Humans; Inhibitory Concentration 50; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Tetrazolium Salts; Thiazoles; Zidovudine

2000
Kinetic evidence for covalent phosphoryl-enzyme intermediate in phosphotransferase activity of human red cell pyrimidine nucleotidases.
    Methods in enzymology, 2002, Volume: 354

    Topics: 5'-Nucleotidase; Animals; Antineoplastic Agents; Antiviral Agents; Catalysis; Cytarabine; Erythrocytes; Humans; Phosphotransferases; Pyrimidine Nucleotides; Rats; Substrate Specificity; Water; Zidovudine

2002
Arabinosylcytosine downregulates thymidine kinase and induces cross-resistance to zidovudine in T-lymphoid cells.
    Biochemical and biophysical research communications, 2003, Aug-01, Volume: 307, Issue:3

    Topics: Anti-HIV Agents; ATP Binding Cassette Transporter, Subfamily B; Blotting, Western; Cell Line; Cytarabine; Dose-Response Relationship, Drug; Down-Regulation; Drug Resistance; T-Lymphocytes; Thymidine Kinase; Zidovudine

2003
2', 3'-Dideoxycytidine represses thymidine kinases 1 and 2 expression in T-lymphoid cells.
    Life sciences, 2004, Jan-02, Volume: 74, Issue:7

    Topics: Anti-HIV Agents; Blotting, Western; Cells, Cultured; Cytarabine; DNA Primers; Down-Regulation; Drug Resistance, Multiple; Gene Expression Regulation, Enzymologic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; T-Lymphocytes; Thymidine Kinase; Zalcitabine; Zidovudine

2004
Structural studies of nucleoside analog and feedback inhibitor binding to Drosophila melanogaster multisubstrate deoxyribonucleoside kinase.
    The FEBS journal, 2008, Volume: 275, Issue:9

    Topics: Adenosine Diphosphate; Animals; Antimetabolites; Bromodeoxyuridine; Cytarabine; Cytidine Triphosphate; Drosophila melanogaster; Drosophila Proteins; Feedback; Floxuridine; Guanosine Triphosphate; Hydrogen Bonding; Inhibitory Concentration 50; Kinetics; Models, Chemical; Models, Molecular; Phosphotransferases (Alcohol Group Acceptor); Protein Binding; Protein Structure, Secondary; Structure-Activity Relationship; Thymine Nucleotides; X-Ray Diffraction; Zalcitabine; Zidovudine

2008
Identification of the amino acid-AZT-phosphoramidase by affinity T7 phage display selection.
    Bioorganic & medicinal chemistry letters, 2009, Nov-15, Volume: 19, Issue:22

    Topics: Amides; Amino Acids; Anti-HIV Agents; Bacteriophage T7; Cytarabine; Drug Delivery Systems; Drug Design; Humans; Peptide Library; Phosphoric Acids; Virus Replication; Zidovudine

2009
TDP1 repairs nuclear and mitochondrial DNA damage induced by chain-terminating anticancer and antiviral nucleoside analogs.
    Nucleic acids research, 2013, Volume: 41, Issue:16

    Topics: Acyclovir; Animals; Anti-HIV Agents; Antimetabolites, Antineoplastic; Antiviral Agents; Cell Line; Cell Nucleus; Cells, Cultured; Chickens; Cytarabine; DNA Damage; DNA Repair; DNA, Mitochondrial; Gene Deletion; Mice; Phosphoric Diester Hydrolases; Zalcitabine; Zidovudine

2013
Surmounting Cytarabine-resistance in acute myeloblastic leukemia cells and specimens with a synergistic combination of hydroxyurea and azidothymidine.
    Cell death & disease, 2019, 05-17, Volume: 10, Issue:6

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cytarabine; Deoxycytidine Kinase; DNA Damage; Drug Resistance, Neoplasm; Drug Synergism; Histones; Humans; Hydroxyurea; Leukemia, Myeloid, Acute; Ubiquitination; Zidovudine

2019