Page last updated: 2024-08-23

zidovudine and cidofovir anhydrous

zidovudine has been researched along with cidofovir anhydrous in 25 studies

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (24.00)18.2507
2000's11 (44.00)29.6817
2010's7 (28.00)24.3611
2020's1 (4.00)2.80

Authors

AuthorsStudies
Andrei, G; Balzarini, J; Blache, Y; Chapat, JP; Chavignon, O; De Clercq, E; Debouzy, JC; Elhakmaoui, A; Essassi, EM; Gueiffier, A; Kerbal, A; Lhassani, M; Snoeck, R; Teulade, JC; Witvrouw, M1
Andrei, G; De Clercq, E; Dimas, K; Foscolos, GB; Fytas, G; Kolocouris, A; Kolocouris, N; Pannecouque, C; Snoeck, R; Stamatiou, G; Witvrouw, M; Zoidis, G1
Balzarini, J; Barral, K; Camplo, M; De Clercq, E; Hider, RC; Neyts, J1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Lombardo, F; Obach, RS; Waters, NJ1
Chou, KC; González-Díaz, H; Martinez de la Vega, O; Prado-Prado, FJ; Ubeira, FM; Uriarte, E1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Benet, LZ; Brouwer, KL; Chu, X; Dahlin, A; Evers, R; Fischer, V; Giacomini, KM; Hillgren, KM; Hoffmaster, KA; Huang, SM; Ishikawa, T; Keppler, D; Kim, RB; Lee, CA; Niemi, M; Polli, JW; Sugiyama, Y; Swaan, PW; Tweedie, DJ; Ware, JA; Wright, SH; Yee, SW; Zamek-Gliszczynski, MJ; Zhang, L1
Kesel, AJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Aldern, KA; Beadle, JR; Broker, TR; Buckheit, RW; Chow, LT; Harden, EA; Hartman, T; Hostetler, KY; Keith, KA; Prichard, MN; Valiaeva, N; Yang, G; Yu, JH1
Andrei, G; Buckheit, RW; De Jonghe, S; Groaz, E; Hartman, T; Herdewijn, P; Kalkeri, R; Luo, M; Ptak, RG; Schols, D; Snoeck, R1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Balzarini, J; Bron, D; De Clercq, E; Delforge, A; Lagneaux, L; Snoeck, R; Stryckmans, P; Van der Auwera, P1
Allen, SJ; Chen, MS; Cherrington, JM; McKee, BH1
Cundy, KC; Fisher, PE; Jaffe, HS; Lietman, PS; Pastelak, A; Petty, BG; Wachsman, M1
Hou, J; Major, EO1
Di Perri, G; Maiello, A; Quario, M; Racca, D; Sinicco, A; Zeme, DA1
Cauda, R; Cingolani, A; De Luca, A; Di Giambenedetto, S; Marzocchetti, A; Pompucci, A; Scoppettuolo, G; Tumbarello, M; Vago, G1
Besnard, M; Chacun, H; Couvreur, P; Hillaireau, H; Janin, J; Le Doan, T1
Chacun, H; Couvreur, P; Hillaireau, H; Janin, J; Le Doan, T1
Chow, WA; Guan, M; Jiang, C1

Reviews

3 review(s) available for zidovudine and cidofovir anhydrous

ArticleYear
Membrane transporters in drug development.
    Nature reviews. Drug discovery, 2010, Volume: 9, Issue:3

    Topics: Animals; Computer Simulation; Decision Trees; Drug Approval; Drug Discovery; Drug Evaluation, Preclinical; Drug Interactions; Humans; Membrane Transport Proteins; Mice; Mice, Knockout; Prescription Drugs

2010
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Anti-HIV drugs for cancer therapeutics: back to the future?
    The Lancet. Oncology, 2009, Volume: 10, Issue:1

    Topics: Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Cidofovir; Cytosine; HIV Protease Inhibitors; Humans; Indinavir; Nelfinavir; Neoplasms; Organophosphonates; Receptors, CXCR4; Reverse Transcriptase Inhibitors; Ritonavir; Saquinavir; Zidovudine

2009

Trials

1 trial(s) available for zidovudine and cidofovir anhydrous

ArticleYear
Pharmacokinetics, safety and bioavailability of HPMPC (cidofovir) in human immunodeficiency virus-infected subjects.
    Antiviral research, 1996, Volume: 29, Issue:2-3

    Topics: Adolescent; Adult; Antiviral Agents; Biological Availability; Cidofovir; Cytosine; Double-Blind Method; Drug Administration Routes; Female; HIV Infections; Humans; Male; Middle Aged; Organophosphonates; Organophosphorus Compounds; Zidovudine

1996

Other Studies

21 other study(ies) available for zidovudine and cidofovir anhydrous

ArticleYear
Synthesis of acyclo-C-nucleosides in the imidazo[1,2-a]pyridine and pyrimidine series as antiviral agents.
    Journal of medicinal chemistry, 1996, Jul-05, Volume: 39, Issue:14

    Topics: Animals; Antiviral Agents; Chlorocebus aethiops; HeLa Cells; Humans; Nucleosides; Pyridines; Pyrimidines; Structure-Activity Relationship; Tumor Cells, Cultured; Vero Cells

1996
New 2-(1-adamantylcarbonyl)pyridine and 1-acetyladamantane thiosemicarbazones-thiocarbonohydrazones: cell growth inhibitory, antiviral and antimicrobial activity evaluation.
    Bioorganic & medicinal chemistry letters, 2002, Mar-11, Volume: 12, Issue:5

    Topics: Bacteria; Cell Division; Cell Line; Formazans; Humans; Hydrazones; Microbial Sensitivity Tests; Molecular Structure; Structure-Activity Relationship; Tetrazolium Salts; Thiosemicarbazones; Tumor Cells, Cultured; Viruses

2002
Synthesis and antiviral evaluation of cyclic and acyclic 2-methyl-3-hydroxy-4-pyridinone nucleoside derivatives.
    Journal of medicinal chemistry, 2006, Jan-12, Volume: 49, Issue:1

    Topics: Animals; Antiviral Agents; Cell Line; Cell Proliferation; Chlorocebus aethiops; Deferiprone; HeLa Cells; Herpesvirus 1, Human; Herpesvirus 2, Human; HIV-1; HIV-2; Humans; Ligands; Microbial Sensitivity Tests; Molecular Structure; Nucleosides; Pyridones; Structure-Activity Relationship; Vero Cells

2006
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Unified QSAR approach to antimicrobials. 4. Multi-target QSAR modeling and comparative multi-distance study of the giant components of antiviral drug-drug complex networks.
    Bioorganic & medicinal chemistry, 2009, Jan-15, Volume: 17, Issue:2

    Topics: Anti-Infective Agents; Antiviral Agents; Artificial Intelligence; Computer Simulation; Drug Evaluation, Preclinical; Molecular Structure; Quantitative Structure-Activity Relationship

2009
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Broad-spectrum antiviral activity including human immunodeficiency and hepatitis C viruses mediated by a novel retinoid thiosemicarbazone derivative.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:5

    Topics: Anti-Bacterial Agents; Benzaldehydes; Cell Line, Tumor; Chromatography, Thin Layer; Cytomegalovirus; Hepacivirus; Herpesvirus 3, Human; HIV-1; Humans; Microbial Sensitivity Tests; Molecular Structure; Retinoids; Stereoisomerism; Structure-Activity Relationship; Thiosemicarbazones

2011
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Synthesis and Antiviral Evaluation of Octadecyloxyethyl Benzyl 9-[(2-Phosphonomethoxy)ethyl]guanine (ODE-Bn-PMEG), a Potent Inhibitor of Transient HPV DNA Amplification.
    Journal of medicinal chemistry, 2016, 12-08, Volume: 59, Issue:23

    Topics: Antiviral Agents; Cell Line, Tumor; DNA, Viral; Dose-Response Relationship, Drug; Guanine; HEK293 Cells; Herpesvirus 2, Human; HIV; Humans; Leukocytes, Mononuclear; Molecular Structure; Nucleic Acid Amplification Techniques; Organophosphonates; Papillomaviridae; Structure-Activity Relationship; Virus Replication

2016
Expanding the Antiviral Spectrum of 3-Fluoro-2-(phosphonomethoxy)propyl Acyclic Nucleoside Phosphonates: Diamyl Aspartate Amidate Prodrugs.
    Journal of medicinal chemistry, 2017, 07-27, Volume: 60, Issue:14

    Topics: Adenine; Anti-HIV Agents; Antiviral Agents; Aspartic Acid; Cell Line; Cytomegalovirus; Drug Resistance, Viral; Drug Stability; Esters; Hepatitis B virus; Herpesvirus 3, Human; Humans; Hydrogen-Ion Concentration; Microsomes, Liver; Nucleosides; Organophosphonates; Prodrugs; Stereoisomerism; Structure-Activity Relationship

2017
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
Inhibitory effects of potent inhibitors of human immunodeficiency virus and cytomegalovirus on the growth of human granulocyte-macrophage progenitor cells in vitro.
    European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 1990, Volume: 9, Issue:8

    Topics: Adenine; Adult; Antiviral Agents; Bone Marrow; Bone Marrow Cells; Cells, Cultured; Cidofovir; Cytomegalovirus; Cytosine; Foscarnet; Ganciclovir; Granulocytes; Hematopoietic Stem Cells; HIV; Humans; Macrophages; Organophosphonates; Organophosphorus Compounds; Phosphonoacetic Acid; Zidovudine

1990
Kinetic analysis of the interaction between the diphosphate of (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine, ddCTP, AZTTP, and FIAUTP with human DNA polymerases beta and gamma.
    Biochemical pharmacology, 1994, Nov-16, Volume: 48, Issue:10

    Topics: Antiviral Agents; Arabinofuranosyluracil; Cidofovir; Cytosine; Dideoxynucleotides; DNA Polymerase I; DNA Polymerase III; Herpesvirus 1, Human; Herpesvirus 2, Human; Humans; Kinetics; Nucleic Acid Synthesis Inhibitors; Organophosphonates; Organophosphorus Compounds; Thymine Nucleotides; Zalcitabine; Zidovudine

1994
The efficacy of nucleoside analogs against JC virus multiplication in a persistently infected human fetal brain cell line.
    Journal of neurovirology, 1998, Volume: 4, Issue:4

    Topics: Anti-HIV Agents; Antiviral Agents; Brain; Cells, Cultured; Cidofovir; Cytarabine; Cytosine; DNA, Viral; Enzyme Inhibitors; Fetus; Humans; JC Virus; Neurons; Nucleosides; Organophosphonates; Organophosphorus Compounds; Papillomavirus Infections; Topotecan; Tumor Virus Infections; Virus Replication; Zidovudine

1998
Advances, challenges and growing frustration.
    PI perspective, 1995, Issue:no 16

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Cachexia; Cidofovir; Cytomegalovirus Infections; Cytosine; Drug Costs; Drug Therapy, Combination; Growth Hormone; HIV Protease Inhibitors; HIV Reverse Transcriptase; HIV-1; Humans; Immunity, Cellular; Infectious Disease Transmission, Vertical; Organophosphonates; Organophosphorus Compounds; Politics; Reverse Transcriptase Inhibitors; Zidovudine

1995
A case of flare syndrome.
    Le infezioni in medicina, 2001, Volume: 9, Issue:3

    Topics: Acute Disease; Adult; AIDS-Related Opportunistic Infections; Antiretroviral Therapy, Highly Active; Antiviral Agents; CD4 Lymphocyte Count; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Drug Therapy, Combination; Ganciclovir; HIV Infections; Humans; Indinavir; Lamivudine; Male; Organophosphonates; Organophosphorus Compounds; Zidovudine

2001
Fatal inflammatory AIDS-associated PML with high CD4 counts on HAART: a new clinical entity?
    Neurology, 2004, Dec-28, Volume: 63, Issue:12

    Topics: Acquired Immunodeficiency Syndrome; Adult; Antiretroviral Therapy, Highly Active; Antiviral Agents; Brain; CD4 Lymphocyte Count; Cidofovir; Cytosine; Dideoxynucleosides; Encephalitis; False Negative Reactions; Fatal Outcome; Humans; Immunocompromised Host; Indinavir; JC Virus; Lamivudine; Leukoencephalopathy, Progressive Multifocal; Magnetic Resonance Imaging; Male; Organophosphonates; Substance Abuse, Intravenous; Time Factors; Virus Activation; Zidovudine

2004
Encapsulation of antiviral nucleotide analogues azidothymidine-triphosphate and cidofovir in poly(iso-butylcyanoacrylate) nanocapsules.
    International journal of pharmaceutics, 2006, Oct-31, Volume: 324, Issue:1

    Topics: Anti-HIV Agents; Capsules; Chromatography, High Pressure Liquid; Cidofovir; Cyanoacrylates; Cytosine; Drug Compounding; Enbucrilate; Freeze Drying; Microscopy, Electron, Scanning; Organophosphonates; Particle Size; Polymers; Zidovudine

2006
Encapsulation of mono- and oligo-nucleotides into aqueous-core nanocapsules in presence of various water-soluble polymers.
    International journal of pharmaceutics, 2007, Mar-01, Volume: 331, Issue:2

    Topics: Cations; Chitosan; Cidofovir; Cyanoacrylates; Cytosine; Dideoxynucleotides; Drug Carriers; Enbucrilate; Materials Testing; Nanocapsules; Nucleotides; Oligonucleotides; Organophosphonates; Permeability; Polyethyleneimine; Polymers; Solubility; Thymine Nucleotides; Water; Zidovudine

2007