zidovudine has been researched along with antipyrine in 19 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 8 (42.11) | 18.2507 |
| 2000's | 8 (42.11) | 29.6817 |
| 2010's | 3 (15.79) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL | 1 |
| Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 1 |
| Jolivette, LJ; Ward, KW | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S | 1 |
| Campillo, NE; Guerra, A; Páez, JA | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Brockmeyer, NH; Goos, M; Mertins, L; Spatz, D; Tillmann, I | 1 |
| Henderson, GI; Johnson, RF; King, TS; Schenken, RS; Schenker, S | 1 |
| Hamby, RL; Henderson, GI; Perez, AB; Schenken, RS; Schenker, S; Yang, Y | 1 |
| al-Habet, S; Ravasco, RJ; Tuntland, T; Unadkat, JD | 1 |
| Baughman, WL; Massarella, J; Nosbisch, C; Tuntland, T; Unadkat, JD | 1 |
| Blaschke, T; Campbell, TB; Collier, A; Kahn, J; Kuritzkes, DR; Messari, F; Phair, J; Pottage, JC; Rosandich, ME; Schooley, RT; Stein, DS | 1 |
| Barthel, B; Brockmeyer, NH; Goos, M; Mertins, L; Tillmann, I | 1 |
| Nosbisch, C; Odinecs, A; Tuntland, T; Unadkat, JD | 1 |
1 trial(s) available for zidovudine and antipyrine
| Article | Year |
|---|---|
Phase 1 study of combination therapy with L-697,661 and zidovudine. The ACTG 184 Protocol Team.
Topics: Adult; Antipyrine; Antiviral Agents; Base Sequence; Benzoxazoles; Cross-Over Studies; DNA Primers; DNA, Viral; Drug Interactions; Drug Resistance, Microbial; Drug Therapy, Combination; Female; Genes, pol; Genotype; HIV Seropositivity; HIV-1; Humans; Male; Molecular Sequence Data; Pilot Projects; Pyridones; Reverse Transcriptase Inhibitors; Zidovudine | 1996 |
18 other study(ies) available for zidovudine and antipyrine
| Article | Year |
|---|---|
Cheminformatic models to predict binding affinities to human serum albumin.
Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids | 2001 |
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
Extrapolation of human pharmacokinetic parameters from rat, dog, and monkey data: Molecular properties associated with extrapolative success or failure.
Topics: Algorithms; Animals; Dogs; Haplorhini; Humans; Pharmaceutical Preparations; Pharmacokinetics; Rats; Species Specificity; Tissue Distribution | 2005 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship | 2009 |
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2010 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Endogenous interferon plasma levels and antipyrine pharmacokinetics in patients with viral infections.
Topics: Acquired Immunodeficiency Syndrome; Adult; Antipyrine; Female; Humans; Interferons; Male; Radioimmunoassay; Respiratory Tract Infections; Virus Diseases; Zidovudine | 1992 |
Azidothymidine (zidovudine) transport by the human placenta.
Topics: Antipyrine; Biological Transport; Female; Humans; Kinetics; Placenta; Pregnancy; Zidovudine | 1990 |
Transfer of dideoxyinosine across the human isolated placenta.
Topics: Antipyrine; Biological Transport; Chromatography, High Pressure Liquid; Didanosine; Female; Glucose; Humans; Hydrogen-Ion Concentration; Hypoxanthine; Hypoxanthines; In Vitro Techniques; Inosine; Maternal-Fetal Exchange; Perfusion; Placenta; Pregnancy; Uric Acid; Zidovudine | 1994 |
Efflux of zidovudine and 2',3'-dideoxyinosine out of the cerebrospinal fluid when administered alone and in combination to Macaca nemestrina.
Topics: Animals; Antipyrine; Chromatography, High Pressure Liquid; Didanosine; Drug Interactions; Female; Macaca nemestrina; Male; Zidovudine | 1994 |
Mechanism and rate of placental transfer of zalcitabine (2',3'-dideoxycytidine) in Macaca nemestrina.
Topics: Amniotic Fluid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antipyrine; Antiviral Agents; Cattle; Cross-Over Studies; Drug Interactions; Female; Fetal Blood; Macaca nemestrina; Placenta; Pregnancy; Random Allocation; Zalcitabine; Zidovudine | 1996 |
Pharmacokinetic interaction of fluconazole and zidovudine in HIV-positive patients.
Topics: 17-Hydroxycorticosteroids; Acquired Immunodeficiency Syndrome; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Antifungal Agents; Antipyrine; Candidiasis, Oral; Drug Interactions; Drug Therapy, Combination; Fluconazole; Half-Life; Humans; Hydrocortisone; Male; Zidovudine | 1997 |
In vivo maternal-fetal-amniotic fluid pharmacokinetics of zidovudine in the pigtailed macaque: comparison of steady-state and single-dose regimens.
Topics: Amniotic Fluid; Animals; Anti-HIV Agents; Anti-Inflammatory Agents, Non-Steroidal; Antipyrine; Female; Fetal Blood; Macaca nemestrina; Maternal-Fetal Exchange; Metabolic Clearance Rate; Pregnancy; Zidovudine | 1998 |