Page last updated: 2024-08-23

zidovudine and adenine

zidovudine has been researched along with adenine in 182 studies

Research

Studies (182)

TimeframeStudies, this research(%)All Research%
pre-19904 (2.20)18.7374
1990's30 (16.48)18.2507
2000's80 (43.96)29.6817
2010's67 (36.81)24.3611
2020's1 (0.55)2.80

Authors

AuthorsStudies
Singh, SK; Yadav, A1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Balzarini, J; Bergamini, A; Calio, R; De Clercq, E; Milanese, G; Pauwels, R; Perno, CF; Rocchi, G; Yarchoan, R1
Beer, B; Donath, A; Egberink, HF; Hartmann, K; Hoffmann-Fezer, G; Horzinek, MC; Lutz, H; Thefeld, S; Thum, I1
Balzarini, J1
Egberink, HF; Hartman, K; Horzinek, MC1
De Clercq, E; Lin, JC; Pagano, JS1
Broder, S; Kageyama, S; Mitsuya, H; Yarchoan, R1
Balzarini, J; Bronson, R; De Clercq, E; Jaenisch, R; Lee, JS; Mullaney, S; Ruprecht, RM; Sharpe, AH1
Balzarini, J; Borst, M; De Clercq, E; Egberink, H; Horzinek, M; Koolen, M; Neu, H; Niphuis, H; Schellekens, H1
Bernaerts, R; Holý, A; Hrebabecký, H; Merta, A; Otmar, M; Rosenberg, I; Votruba, I1
Balzarini, J; Bron, D; De Clercq, E; Delforge, A; Lagneaux, L; Snoeck, R; Stryckmans, P; Van der Auwera, P1
Balzarini, J; De Clercq, E; Naesens, L; Sobis, H; Vandeputte, M1
Balzarini, J; De Clercq, E; Naesens, L1
Chisaka, O; Matsubara, K; Nagahata, T; Tsurimoto, T; Ueda, K1
Brian, EL; De Clercq, E; Pagano, JS; Smith, MS1
Balzarini, J; Cozens, RM; De Clercq, E; Gangemi, JD; Hochkeppel, HK1
De Clercq, E; Gil-Fernández, C1
Fridland, A; Gong, YF; Marshall, DR; Srinivas, RV1
de Górgolas Hernández-Mora, M; Fernández Guerrero, ML; Verdejo Morcillo, C1
Aubertin, AM; Gosselin, G; Imbach, JL; Kirn, A; Lefebvre, I; Pompon, A; Puech, F1
Holý, A; Merta, A; Stĕtina, R; Votruba, I1
Ahmed, PS; Brennan, TM; Bridges, CG; Casara, P; Hornsperger, JM; Navé, JF; Taylor, DL; Tyms, AS1
Allen, SJ; Chen, MS; Cherrington, JM; Fuller, MD; Kunder, SC; Lesnikowski, Z; Mulato, AS; Schinazi, RF; Sommadossi, JP; Ussery, MA1
Anton, KE; Cherrington, JM; Hellmann, NS; Lamy, PD; Li, WX; Miller, MD; Mulato, AS1
Baba, M; De Clercq, E; Makino, M; Okada, Y; Suruga, Y; Tanaka, H1
Balzarini, J; De Clercq, E; Hatse, S1
Anton, KE; Cherrington, JM; Lamy, PD; Miller, MD; Mulato, AS1
Black, RJ1
Mickle, T; Nair, V1
Connelly, MC; Flynn, PM; Fridland, A; Kumar, A; Paibir, SG; Schuetz, JD; Srinivas, RV; Sun, D1
Drazan, V; Vetterl, V1
Cheng, B1
Buckheit, R; Gilbert, H; Margot, N; Miller, M; Palmer, S; Shaw, N1
Miller, MD; Naeger, LK1
Birkus, G; Cihlar, T; Greenwalt, DE; Hitchcock, MJ1
Margot, NA; Miller, MD; Naeger, LK1
Prescott, LM1
Carnevali, A; Casabianca, A; Franchetti, P; Magnani, M; Orlandi, C; Rossi, L; Schiavano, GF; Serafini, S1
Balzarini, J; Van Herrewege, Y; Vanham, G1
Bacheler, L; Erickson-Viitanen, S; Gallagher, K; Garber, S; Geleziunas, R; Otto, MJ; Schinazi, RF; Shi, G; Wu, JT; Zhang, H1
Derse, D; Hill, SA; Lloyd, PA; McDonald, S; Wykoff, J1
Balestra, E; Cappellacci, L; Forbici, F; Franchetti, P; Grifantini, M; Magnani, M; Pasqualini, M; Perno, CF; Rossi, L; Serafini, S1
Boretto, J; Canard, B; Courcambeck, J; Deval, J; Halfon, P; Miller, MD; Parkin, NT; Selmi, B; White, KL1
Choi, BG; Hong, JH; Kwak, EY; Park, Y1
Akula, N; Chong, Y; Chu, CK1
Boyle, BA1
Bates, M; Chappey, C; Clair, MS; Fisher, R; Lanier, ER; Parkin, N; Ross, L; Tisdale, M1
Ambudkar, SV; Nandigama, K; Sauna, ZE1
Auclair, M; Capeau, J; Caron, M; Kornprobst, M; Lagathu, C; Lombès, A; Walker, UA1
Berger, F; Gatell, J; Hoffmann, C; Holm, S; Kuhlmann, B; Martínez, E; Mauss, S; Milinkovic, A; Schmutz, G1
Feinberg, J1
Abraira, V; Antela, A; Casado, JL; Dronda, F; Gutiérrez, C; López, D; Moreno, A; Moreno, S; Pérez-Elías, MJ; Rodríguez, MA1
D'Agostino, C; d'Ettorre, G; Lichtner, M; Massetti, AP; Mastroianni, CM; Vullo, V1
Amin, J; Carr, A; Cooper, DA; McAllister, J; Winston, A1
Bower, M; Davies, E; Gazzard, B; Latham, V; Mandalia, S; Michailidis, C; Nelson, M; Stebbing, J1
Girault, V1
Arribas, JR; Campo, RE; Cheng, AK; Chuck, S; DeJesus, E; Enejosa, J; Gallant, JE; Gazzard, B; Lu, B; McColl, D; Pozniak, AL; Toole, JJ1
Fisher, M; Gazzard, B; Higgs, C; Johnson, M; Mandalia, S; Moyle, G; Nelson, M; Teague, A1
Balestre, E; Boucher, S; Capdepont, S; Dabis, F; Dupon, M; Fleury, H; Masquelier, B; Thiébaut, R1
Bacheler, L; Koontz, D; Mellors, JW; Parikh, UM1
Antunes, F; Chiesi, A; Goebel, FD; Katlama, C; Knysz, B; Ledergerber, B; Lundgren, JD; Mocroft, A; Phillips, AN; Reiss, P1
Hammerstrom, TS; Laessig, KA; Lewis, LL1
Jenny-Avital, ER1
Fätkenheuer, G; Lehmann, C; Wyen, C1
Alvarez, ML; Cihlar, T; Cordobilla, B; Domingo, JC; Domingo, P; Giralt, M; Guallar, J; López-Dupla, M; Sánchez de la Rosa, R; Saumoy, M; Torres, F; Vidal, F; Villarroya, F1
Cartledge, J; Churchill, D; Fakoya, A; Hay, P; Johnson, M; Leen, C; Moyle, GJ; Murphy, M; Reilly, G; Sabin, CA; Scullard, G; Wilkins, E1
Arribas, JR; Campo, RE; Chen, SS; Cheng, AK; DeJesus, E; Enejosa, J; Gallant, JE; Gazzard, B; McColl, D; Pozniak, AL; Toole, JJ1
Bernard-Henry, C; Cheneau, C; de Mautort, E; Hess, G; Krebs, M; Lang, JM; Partisani, M; Priester, M; Rey, D1
d'Ettorre, G; Mastroianni, CM; Vullo, V1
Mellors, JW; Parikh, UM; Sheen, CW; Sluis-Cremer, N; Torres, PS; Zelina, S1
Barreiro, P; Blanco, F; de Mendoza, C; García-Benayas, T; Gil, P; González-Lahoz, J; Maida, I; Martín-Carbonero, L; Soriano, V1
Bainbridge, A; Jäger, HR; Miller, RF; Usiskin, SI1
Boucher, S; Fleury, H; Lavignolle-Aurillac, V; Masquelier, B; Neau, D; Ragnaud, JM; Recordon-Pinson, P; Schrive, MH1
Benech, H; Da Silva, D; Durand-Gasselin, L; Grassi, J; Pruvost, A1
Baba, M; De Clercq, E; Shi, M; Takao, S; Wang, X1
Götte, M; Ly, JK; Marchand, B; Margot, NA; McDermott, M; Miller, MD; Wang, R; White, KL1
Antenozzi, S; Hulse, S; Luque, A; Shahzad, U; Smith, B; Tanzman, E; Wang, D1
Hong, SK; Lee, SG; Paik, SY; Park, SS; Yoo, WC; Yoon, JS1
Cascone, A; Colella, G; Di Martino, F; Filippini, A; Filippini, P; Lanza, A; Martini, S; Masiello, A; Pisapia, R1
Doerr, HW; Staszewski, S; Stürmer, M1
Bridges, AS; Cohen, MS; Corbett, AH; Dumond, JB; Jung, BH; Kashuba, AD; Patterson, KB; Rezk, NL; Stewart, PW; Yeh, RF1
Brenner, BG; Lalonde, R; Micheli, V; Moisi, D; Ntemgwa, M; Oliveira, M; Wainberg, MA1
Ainsworth, J; Booth, C; Bradshaw, D; Geretti, AM; Malik, S; Pattery, T; Van Houtte, M; Waters, A1
Arribas, JR; Campo, RE; Chen, SS; Cheng, AK; Dejesus, E; Enejosa, J; Gallant, JE; Gazzard, B; Holmes, CB; McColl, D; Pozniak, AL; Toole, JJ1
Doerries, R; Drechsler, H; Gass, A; Hardmeier, M; Kuhle, J; Mehling, M; Ruegg, S1
Herrera, L; Moreno, S; Sánchez-de la Rosa, R1
Abla, N; Chinn, LW; Ferrin, TE; Giacomini, KM; Huang, CC; Johns, SJ; Kawamoto, M; Kroetz, DL; Liu, L; Nakamura, T; Stryke, D; Taylor, TR1
Bonjoch, A; Clotet, B; Domingo, P; Galindo, MJ; Iribarren, J; Llibre, JM; Martinez-Picado, J; Negredo, E; Pérez-Alvarez, N; Schapiro, J1
Cortes, C; Domingo, P; Ferrer, E; Gatell, JM; Gutierrez, M; Leon, A; Niubo, J; Pedrol, E; Podzamczer, D; Puig, T; Sanchez, P; Veloso, S1
Cotter, BR; Currier, JS; Dubé, MP; Fichtenbaum, CJ; Gerschenson, M; Komarow, L; Mitchell, CK; Murphy, RL; Parker, RA; Squires, K; Stein, JH; Torriani, FJ1
Amin, J; Avihingsanon, A; Bowden, S; Cooper, DA; Dore, GJ; Lewin, SR; Locarnini, S; Marks, P; Matthews, GV; Petcharapirat, P; Rerknimitr, R; Ruxrungtham, K; Sasadeusz, J1
Chen, SS; Cheng, AK; DeJesus, E; Enejosa, JV; Gallant, JE; Pozniak, AL; Winston, JA1
Atté, EF; Rasschaert, F; Reid, T; van Griensven, J; Zachariah, R1
Portilla, J1
Benoist, JF; Buck, NE; Hu, R; Ioannou, PA; Khaniani, MS; Li, L; Peters, HL; Sarsero, JP; Vadolas, J; Wardan, H; Wood, L1
Buck, NE; Hu, R; Peters, HL; Wood, L1
Dauer, B; Gute, P; Khaykin, P; Klauke, S; Staszewski, S; Stephan, C; Stuermer, M1
Foster, C; Gibb, DM; Lyall, H; Olmscheid, B; Pearce, G; Zhang, S1
Benn, P; Cartledge, J; Edwards, SG; Linney, A; Moyle, G; Reilly, G; Ruff, C; Sabin, CA; Sauret-Jackson, V1
Arasteh, K; Ebrahimi, R; Fenske, S; Freiwald, M; Gallo, L; Kuhlmann, B; Mertenskoetter, T; Ranneberg, R; Weitner, L1
Ebrahimi, R; Ewan, J; Fisher, M; Kingston, M; Liu, H; Moyle, GJ; Orkin, C; Reilly, G; Shahmanesh, M; Wilkins, E1
Cohen, C; Dejesus, E; Elion, R; Gathe, JC; Ha, B; Hsu, RK; Lanier, R; Paulsen, D; Redfield, RR; Ross, L; Yau, L1
Andreotti, M; Antonelli, G; Ceccarelli, G; d'Ettorre, G; Massetti, P; Mastroianni, CM; Rizza, C; Turriziani, O; Vella, S; Vullo, V1
Cheng, AK; Enejosa, J; Margot, NA; McColl, DJ; Miller, MD1
Amuron, B; Birungi, J; Bunnell, R; Coutinho, A; Foster, S; Grosskurth, H; Jaffar, S; Kyomuhangi, R; Levin, J; Mermin, J; Nabiryo, C; Namara, G; Ndembi, N; Opio, A; Tappero, JW1
Abaine, D; Aber, M; Ahimbisibwe, F; Akao, J; Akuma, S; Amuron, B; Amurwon, J; Angweng, E; Anywar, W; Atwiine, D; Atwiine, S; Awio, P; Babiker, A; Babiker, AG; Bafana, T; Bagaya, L; Bahendeka, S; Bakeinyaga, GT; Barungi, G; Bassett, M; Bohannon, J; Boocock, K; Borok, M; Bray, D; Breckenridge, A; Bulaya-Tembo, R; Buluma, E; Burke, A; Burke, C; Byakwaga, H; Byamukama, A; Byaruhanga, R; Chakonza, L; Chidziva, E; Chigwedere, E; Chimanzi, J; Chimbetete, C; Chirairo, H; Chirara, M; Chirema, O; Chitsungo, S; Chivhunga, T; Coutinho, A; Darbyshire, JH; Drasiku, A; Dunn, D; Enzama, R; Etukoit, B; Fadhiru, K; Ferrier, A; Florence, A; Foster, S; Gazzard, B; Generous, L; Gibb, DM; Gilks, C; Gilks, CF; Goodall, R; Grosskurth, H; Grundy, C; Haguma, W; Hakim, J; Hill, C; Hughes, P; Jamu, A; Jangano, M; Jones, S; Kabanda, J; Kabuye, G; Kagina, G; Kajungu, D; Kaleebu, P; Kambungu, A; Kankunda, R; Karungi, J; Kasirye, R; Katabira, E; Katabira, H; Katundu, P; Khauka, P; Kigozi, J; Kikaire, B; Kityo, C; Komugyena, J; Kulume, R; Kusiima, A; Kyomugisha, H; Labeja, O; Lara, AM; Latif, A; Levin, J; Lubwama, E; Lutwama, F; Lyagoba, F; Machingura, I; Machingura, J; Makota, S; Mambule, I; Mapinge, F; Mapuchere, C; Massa, R; Matenga, J; Matongo, M; Maweni, C; Mawora, A; McCormick, A; McLaren, A; Mdege, N; Moyo, K; Muchabaiwa, L; Mudzingwa, S; Mufuka-Kapuya, C; Muganzi, A; Mugisha, A; Mugurungi, O; Mugyenyi, P; Muhweezi, D; Muhwezi, A; Mukiibi, S; Mukose, A; Mulindwa, G; Mulindwa, M; Munderi, P; Murungi, S; Musana, H; Musoro, G; Mutowo, J; Mutsai, S; Muvirimi, C; Muyingo, S; Muzambi, M; Mwebesa, D; Mwesigwa, P; Nabankema, E; Nabongo, P; Naidoo, B; Nairuba, R; Nakahima, W; Nakazibwe, M; Nakiyingi, J; Nalumenya, R; Namale, L; Namara, W; Namata, I; Namazzi, A; Namuli, T; Namyalo, M; Nanfuka, A; Nanfuka, R; Nassuna, G; Ndembi, N; Newland, C; Ngorima, N; Nimwesiga, E; Nsibambi, D; Nyachwo, L; Nyiraguhirwa, D; Ochai, R; Ojiambo, H; Ojiambo, W; Oketta, F; Omony, W; Otim, T; Oyugi, J; Palfreeman, A; Pascoe, M; Pearce, G; Peto, L; Peto, T; Phiri, M; Pillay, D; Pozniak, A; Puddephatt, C; Rahim, S; Rauchenberger, M; Reid, A; Robertson, V; Ronald, A; Rooney, J; Ruberantwari, A; Rutikarayo, N; Sabiiti, J; Sadik, F; Sematala, F; Serwadda, D; Sheehan, S; Simango, M; Smith, M; Snowden, W; Spencer-Drake, C; Spyer, M; Ssali, F; Steens, JM; Svovanapasis, P; Takubwa, J; Taylor, K; Taziwa, F; Tinago, G; Todd, J; Tugume, S; Tukamushaba, J; Tumukunde, D; Tumusiime, C; Twijukye, C; Vere, L; Waita, R; Wakholi, BN; Walker, AS; Walusimbi, J; Wangati, K; Wanyama, J; Wapakhabulo, AC; Warambwa, C; Warara, R; Wavamunno, P; Weller, I; Whitworth, J; Wilkes, H; Winogron, D; Yirrell, D; Zalwango, A; Zalwango, E; Zawedde, C; Zengeza, E1
Cohen, C; DeJesus, E; Elion, R; Gerondelis, P; Ha, B; Horton, J; Lanier, ER; Ross, LL; Rouse, E1
Boothby, M; Gathercole, LL; McGee, KC; McTernan, PG; Nightingale, P; Shahmanesh, M; Shojaee-Moradie, F; Tomlinson, JW; Umpleby, AM1
Bender, MA; Flanigan, T; Freedberg, KA; Kumarasamy, N; Lu, Z; Mayer, KH; Schackman, BR; Scott, CA; Walensky, RP; Wang, B1
Battegay, M; Bernasconi, E; Cavassini, M; Elzi, L; Furrer, H; Hirschel, B; Ledergerber, B; Marzolini, C; Vernazza, P; Weber, R1
Calvez, V; Grant, PM; Marcelin, AG; Nevins, AB; Taylor, J; Wirden, M; Zolopa, AR1
Burdick, R; Chaipan, C; Delviks-Frankenberry, KA; Hu, WS; Paprotka, T; Pathak, VK; Venkatachari, NJ1
Brown, LB; Eron, JJ; Hosseinipour, MC; Kumwenda, JJ; Mhango, B; Mzinganjira, D; Phiri, S; van Oosterhout, JJ; Weigel, R1
Asboe, D; Dunn, D; Fearnhill, E; Gazzard, B; Pillay, D; Pozniak, A; Price, H1
Burke, A; Chirara, M; Dunn, DT; Gilks, CF; Goodall, RL; Hakim, J; Kaleebu, P; Kityo, C; Lyagoba, F; Munderi, P; Ndembi, N; Pillay, D; Robertson, V; Tugume, S; Yirrell, DL1
Rutherford, GW; Siegfried, N; Spaulding, A1
Arrivé, E; Avit, D; Benaboud, S; Blanche, S; Dabis, F; Ekouévi, DK; Gray, G; Hirt, D; McIntyre, J; Nerrienet, E; Rey, E; Sim, KL; Tréluyer, JM; Urien, S1
Asensi, V; Miró, JM; Rodríguez-Guardado, A; Tuset, M1
Engelman, A; Haim, H; Koh, Y1
Brown, JA; Fowler, JD; Pack, LR; Suo, Z1
Curran, A; Ribera, E1
de Silva, T; Weiss, RA1
Chow, S; Ellermann-Eriksen, S; Hedley, DW; Melchjorsen, J; Minderman, H; O'Loughlin, KL; Paludan, SR; Risør, MW; Søgaard, OS; Tolstrup, M; Østergaard, L1
Cooper, V; Ewan, J; Fisher, M; Horne, R; Liu, HC; Moyle, GJ; Reilly, G1
Anderson, PL; Bushman, LR; Kiser, JJ; Klein, B; Ray, ML; Rower, JE; Zheng, JH1
Bygrave, H; Cleary, S; Ford, N; Gadot, L; Goemaere, E; Hilderbrand, K; Jouquet, G; Kranzer, K; Lee, J; Makakole, L; Trivino, L; Vlahakis, N1
Bolton-Moore, C; Chi, BH; Chintu, NT; Giganti, MJ; Moyo, C; Mulenga, LB; Mwango, A; Schuttner, L; Sheneberger, R; Sikazwe, I; Stringer, EM; Stringer, JS1
Adedeji, AO; Burke, DH; Delviks-Frankenberry, KA; Ding, S; Hachiya, A; Johnson, M; Kirby, KA; Kodama, E; Liu, SL; Marchand, B; Michailidis, E; Mitsuya, H; Ndongwe, TP; Ong, YT; Parniak, MA; Pathak, VK; Rai, DK; Ryan, EM; Sarafianos, SG; Singh, K; Whatley, AS; Zheng, YM1
Abraham, B; Bélec, L; Charpentier, C; Dandy, M; De Dieu Longo, J; Grésenguet, G; Matta, M; Mbelesso, P; Moussa, S; Péré, H1
Gibb, DM; Gilks, CF; Grosskurth, H; Hakim, J; Kityo, C; Mambule, I; Munderi, P; Reid, A; Ssali, F; Stöhr, W; Walker, AS1
Cooper, DA; Duncombe, C; Emery, S; Gill, JM; Kerr, SJ; Li, PC; Puls, R; Taylor-Robinson, SD; Winston, A1
Back, DJ; Else, LJ; Khoo, SH; Taylor, S1
Al-Daghri, NM; Boothby, M; Das, S; Gathercole, LL; Harte, AL; McGee, KC; McTernan, PG; Nightingale, P; Shahmanesh, M; Shojaee-Moradie, F; Tomlinson, JW; Tripathi, G; Umpleby, AM1
Fessel, WJ; Israelski, D; Kagan, R; Kaufman, D; Melikian, GL; Rhee, SY; Robbins, GK; Shafer, RW; Taylor, J; Towner, W; Troia-Cancio, PV; Zolopa, A1
Agu, KA; Akpoigbe, KJ; Badru, T; Chabikuli, O; Eluwa, GI; Hamelmann, C1
Arasteh, K; Boven, K; Crauwels, H; De Wet, J; Gathe, J; Gold, J; Hodder, S; Kumar, P; Mohapi, L; Short, W; Vanveggel, S1
Brinkman, K; Furrer, H; Fux, CA; Garcia, EF; Hoek, FJ; Krediet, RT; Reiss, P; van Straalen, JP; Vrouenraets, SM; Wit, FW1
Chidziva, E; Gibb, DM; Gilks, CF; Grosskurth, H; Hakim, J; Kizito, H; Kyomugisha, H; Munderi, P; Musoke, P; Nalumenya, R; Nathoo, K; Russell, EC; Spyer, M; Tumukunde, D; Walker, AS; Zalwango, E1
Didier, PJ; Michael, H; Mitsuya, H; Murphey-Corb, M; Nyaundi, J; Parniak, MA; Rajakumar, P; Reeve, AB; Sarafianos, SG1
Gibbs, C; Guyer, B; Haddad, M; McColl, DJ; Miller, MD; Su, C1
Carda-Broch, S; Casas-Breva, I; Esteve-Romero, J; Peris-Vicente, J; Rambla-Alegre, M1
Bertagnolio, S; Cambiano, V; Jordan, MR; Lundgren, J; Miners, A; Phillips, AN; Pillay, D; von Wyl, V1
Bonovas, S; Hatzakis, A; Nikolopoulos, G; Tsiodras, S1
Abimiku, A; Ajayi, S; Blattner, WA; Carr, JK; Chang, H; Charurat, M; Elegba, O; Etiebet, MA; Eyzaguirre, LM; Ndembi, N; Nowak, RG; Shepherd, J1
Côté, HC; Hukezalie, KR; Thumati, NR; Wong, JM1
Chen, J; Flexner, C; Fuchs, EJ; Hendrix, CW; Liberman, RG; Louissaint, NA; Skipper, PL; Tannenbaum, SR1
Feng, XM; Huang, SM; Li, AY; Wang, BJ; Wang, JZ; Yang, DL; Zhu, B; Zhu, ZN1
Ananworanich, J; Chomchey, N; Gerschenson, M; Hongchookiat, P; Jadwattanakul, T; Kerr, SJ; Kim, JH; Mathajittiphun, P; Phanuphak, N; Phanuphak, P; Pinyakorn, S; Praihirunyakit, P; Rungrojrat, P; Shikuma, C; Teeratakulpisarn, N; Valcour, V1
Armishaw, J; Cameron, PU; Chuah, J; Cooper, DA; Crowe, SM; Fairley, C; Gouillou, M; Hearps, A; Koelsch, KK; Leeansyah, E; Lewin, SR; Liu, JP; Pierce, AB; Smit, de V; Solomon, A; Spelman, T; Tennakoon, S; Velayudham, P1
Matsuoka, M; Miyazawa, T; Okamoto, M; Shimura, K; Togami, H; Yoshikawa, R1
Brady, JJ; Brinkman, K; Cotter, AG; Furrer, H; Fux, CA; Mallon, PW; Reiss, P; Sabin, CA; Vrouenraets, SM; Wit, FW1
Choo, HW; Davis, J; Fang, J; Hansson, AG; Langdon, G; Layton, G; Tawadrous, M; Vourvahis, M1
Arnett, DK; Bagchi, S; Chi, BH; Heimburger, DC; Kabagambe, EK; Kiage, JN; Koethe, JR; Nyirenda, CK; Wellons, MF1
Amarnath, S; Dropulic, B; Felizardo, TC; Foley, J; Fowler, DH; Medin, JA; Steed, K1
Anglaret, X; Bohoussou, F; Carrou, JL; Danel, C; Eholie, SP; Gabillard, D; Konan, R; Moh, R; Ouattara, E; Peytavin, G1
Aguilar, A; De La Torre, J; Del Arco, A; García-Alegría, J; Olalla, J; Pombo, M; Prada, JL; Ruiz-Mateas, F; Urdiales, D1
Antinori, A; Bansi, L; Boumis, E; Callegaro, A; Ceccherini-Silberstein, F; Dunn, D; Fearnhill, E; Forbici, F; Francisci, D; Maggiolo, F; Mussini, C; Nicastri, E; Palamara, G; Perno, CF; Sabin, C; Santoro, MM; Zazzi, M; Zoncada, A1
Aghokeng, A; Belec, L; Bertagnolio, S; Bunupuradah, T; Burda, S; Cane, P; Cappelli, G; Charpentier, C; Dagnra, AY; de Wit, TF; Deshpande, AK; El-Katib, Z; Eshleman, SH; Fleury, HJ; Fokam, J; Ford, N; Gody, JC; Hamers, RL; Hawkins, CA; Holmes, S; Hosseinipour, MC; Jordan, MR; Kanki, PJ; Katzenstein, D; Koyalta, DD; Kumwenda, JJ; Lallemant, M; Lynen, L; Manosuthi, W; Marconi, VC; Margot, NA; Moussa, S; Ndung'u, T; Ngo-Giang-Huong, N; Nyambi, PN; Orrell, C; Peeters, M; Rhee, SY; Ruxrungtham, K; Schapiro, JM; Schuurman, R; Shafer, RW; Sigaloff, KC; Sirivichayakul, S; Smith, D; Stevens, W; Tang, MW; van Zyl, GU; Wallis, CL; Zolfo, M1
Charalambous, S; Churchyard, GJ; Grant, AD; Hoffmann, CJ; Lewis, JJ; Velen, K1
Kanjanabuch, T; Suankratay, C; Woratanarat, K1
Feucht, N; Hadeler, J; Lanzl, I; Loos, D; Schmid, RM; Schwerdtfeger, C; Spinner, CD1
Arnoczy, G; Campbell, T; Fichtenbaum, CJ; Ha, B; Hicks, C; Koletar, S; Massengale, K; McComsey, GA; Sax, P; Stein, JH; Taiwo, B; Tebas, P; Walsh, K; Wohl, DA1
Boulle, A; Chi, BH; Chimbetete, C; Egger, M; Fox, MP; Gerber, F; Gsponer, T; Hoffmann, CJ; Orrell, C; Prozesky, H; Rohr, J; Wandeler, G; Zwahlen, M1
Awio, P; Dunn, DT; Gilks, CF; Goodall, RL; Kaleebu, P; Kityo, C; Munderi, P; Ndembi, N; Nkurunziza, P; Pattery, T; Pillay, D; van Cauwenberge, A1
Betancor, G; Gómez-Puertas, P; Martínez, MA; Mendieta, J; Menéndez-Arias, L; Nevot, M1
Bloch, N; Huber, AD; Ji, J; Kirby, KA; Landau, NR; Leslie, MD; Lucas, AD; Michailidis, E; Ong, YT; Puray-Chavez, MN; Sarafianos, SG; Schultz, ML1
Clumeck, N; Delforge, M; Ilunga, J; Kabeya, K; Kadiebwe, D; Kapend, L; Kasamba, E; Matanda, S; Milolo, C; Mwamba, C; Necsoi, C; Vaira, D1
Guo, F; Li, T; Lin, Q; Shao, H; Sun, P; Tian, J; Xu, Y; Yu, W; Zhou, X1
Havens, PL; Hazra, R1
Arterburn, S; Castaño, E; Cheng, AK; Chuck, SL; Church, J; Deville, J; Enejosa, JV; Estripeaut, D; Gaur, A; Rathore, M; Rhee, MS; Saez-Llorens, X; White, K1
Bader, J; Glass, TR; Klimkait, T; Labhardt, ND; Lejone, TI; Puga, D; Ringera, I1
Antela, A; Esteban, H; Estébanez, M; Mariño, A; Moreno, S; Navarro, J; Pasquau, J; Perez-Molina, JA; Riera, M; Rivero, A; Rubio, R; Santos, J; Sanz-Moreno, J; Suárez-Lozano, I; Troya, J1
Araújo, PMM; Martins, J; Osório, NS; Poveda, E; Santos-Pereira, A; Soares, H; Souto, B; Triunfante, V1

Reviews

15 review(s) available for zidovudine and adenine

ArticleYear
Chemotherapy of feline immunodeficiency virus infection.
    Journal of the American Veterinary Medical Association, 1991, Nov-15, Volume: 199, Issue:10

    Topics: Adenine; Animals; Antiviral Agents; Cats; Feline Acquired Immunodeficiency Syndrome; Immunodeficiency Virus, Feline; Organophosphonates; Zidovudine

1991
Targeted therapy of human immunodeficiency virus-related disease.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 1991, Volume: 5, Issue:10

    Topics: Acquired Immunodeficiency Syndrome; Adenine; Antiviral Agents; CD4 Antigens; Didanosine; Dideoxynucleosides; Dipyridamole; Drug Synergism; Gene Expression Regulation, Viral; Genes, nef; Genes, rev; Genes, tat; HIV; HIV Protease; Interferon Type I; Organophosphonates; RNA-Directed DNA Polymerase; Stavudine; Transcription, Genetic; Zalcitabine; Zidovudine

1991
[Therapeutic approaches to cryptosporidiosis. A review of the literature].
    Revista clinica espanola, 1993, Volume: 193, Issue:6

    Topics: Adenine; Amprolium; Animals; Azithromycin; Coccidiostats; Colostrum; Cryptosporidiosis; Eflornithine; Humans; Immunoglobulins; Spiramycin; Transfer Factor; Zidovudine

1993
Animal studies of prophylaxis.
    The American journal of medicine, 1997, May-19, Volume: 102, Issue:5B

    Topics: Adenine; Animals; Anti-HIV Agents; Disease Models, Animal; Drug Administration Schedule; Interferon-alpha; Lentivirus Infections; Organophosphonates; Organophosphorus Compounds; Retroviridae Infections; Reverse Transcriptase Inhibitors; Tenofovir; Zidovudine

1997
Mechanisms of HIV-1 nucleoside reverse transcriptase inhibitor resistance: is it all figured out?
    Current opinion in investigational drugs (London, England : 2000), 2001, Volume: 2, Issue:3

    Topics: Adenine; Adenosine Triphosphate; Anti-HIV Agents; Drug Resistance, Microbial; HIV-1; Mutation; Organophosphonates; Organophosphorus Compounds; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Stavudine; Tenofovir; Zidovudine

2001
The continuing evolution of HIV therapy.
    The AIDS reader, 2003, Volume: 13, Issue:12

    Topics: Adenine; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Atazanavir Sulfate; Benzoxazines; Carbamates; CD4 Lymphocyte Count; Cyclopropanes; Delayed-Action Preparations; Deoxycytidine; Didanosine; Dideoxynucleosides; Drug Monitoring; Emtricitabine; Furans; HIV Infections; Humans; Lamivudine; Nevirapine; Oligopeptides; Organophosphates; Organophosphonates; Organophosphorus Compounds; Oxazines; Pyridines; Randomized Controlled Trials as Topic; Stavudine; Sulfonamides; Tenofovir; Treatment Outcome; Viral Load; Zidovudine

2003
[The treatment of HIV infection].
    Presse medicale (Paris, France : 1983), 2005, Nov-19, Volume: 34, Issue:20 Pt 2

    Topics: Adenine; Anti-Retroviral Agents; Carbamates; Chemical and Drug Induced Liver Injury; Clinical Trials as Topic; Drug Therapy, Combination; Furans; HIV Infections; Humans; Lamivudine; Nevirapine; Organophosphates; Organophosphonates; Risk Factors; Sulfonamides; Tenofovir; Zidovudine

2005
Evolving simplified treatment strategies for HIV infection: the role of a single-class quadruple-nucleoside/nucleotide regimen of trizivir and tenofovir.
    Expert opinion on pharmacotherapy, 2006, Volume: 7, Issue:16

    Topics: Adenine; Anti-HIV Agents; Dideoxynucleosides; Drug Combinations; HIV Infections; HIV-1; Humans; Lamivudine; Organophosphonates; Reverse Transcriptase Inhibitors; Tenofovir; Zidovudine

2006
Quadruple nucleoside therapy with zidovudine, lamivudine, abacavir and tenofovir in the treatment of HIV.
    Antiviral therapy, 2007, Volume: 12, Issue:5

    Topics: Adenine; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Dideoxynucleosides; Drug Resistance, Multiple, Viral; HIV Infections; HIV-1; Humans; Lamivudine; Mutation; Organophosphonates; Practice Guidelines as Topic; Reverse Transcriptase Inhibitors; Tenofovir; Treatment Failure; Treatment Outcome; Viral Load; Zidovudine

2007
[Tenofovir as a strategy to avoid or limit adverse effects].
    Enfermedades infecciosas y microbiologia clinica, 2008, Volume: 26 Suppl 8

    Topics: Adenine; Anemia; Anti-HIV Agents; Antimetabolites; Clinical Trials as Topic; DNA, Mitochondrial; Double-Blind Method; Drug Therapy, Combination; Dyslipidemias; Glucose Metabolism Disorders; HIV Infections; HIV-1; HIV-Associated Lipodystrophy Syndrome; Humans; Multicenter Studies as Topic; Organophosphonates; Prospective Studies; Randomized Controlled Trials as Topic; Reverse Transcriptase Inhibitors; Stavudine; Tenofovir; Thymidine; Zidovudine

2008
Tenofovir disoproxil fumarate in pregnancy and prevention of mother-to-child transmission of HIV-1: is it time to move on from zidovudine?
    HIV medicine, 2009, Volume: 10, Issue:7

    Topics: Adenine; Adult; Africa South of the Sahara; Animals; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Bone Diseases; Child; Child, Preschool; Congenital Abnormalities; Disease Models, Animal; Drug Resistance, Viral; Female; Health Services Accessibility; HIV Infections; HIV-1; Humans; Infant; Infant, Newborn; Infectious Disease Transmission, Vertical; Macaca; Mitochondria; Nevirapine; Organophosphonates; Pregnancy; Pregnancy Complications, Infectious; Tenofovir; Zidovudine

2009
Tenofovir or zidovudine in three-drug combination therapy with one nucleoside reverse transcriptase inhibitor and one non-nucleoside reverse transcriptase inhibitor for initial treatment of HIV infection in antiretroviral-naïve individuals.
    The Cochrane database of systematic reviews, 2010, Oct-06, Issue:10

    Topics: Adenine; Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Child; Cyclopropanes; Deoxycytidine; Drug Therapy, Combination; Emtricitabine; HIV Infections; Humans; Lamivudine; Nevirapine; Organophosphonates; Reverse Transcriptase Inhibitors; Tenofovir; Zidovudine

2010
From old to new nucleoside reverse transcriptase inhibitors: changes in body fat composition, metabolic parameters and mitochondrial toxicity after the switch from thymidine analogs to tenofovir or abacavir.
    Expert opinion on drug safety, 2011, Volume: 10, Issue:3

    Topics: Adenine; Adipose Tissue; Body Composition; Dideoxynucleosides; Drug Substitution; Humans; Metabolism; Mitochondria; Organophosphonates; Reverse Transcriptase Inhibitors; Stavudine; Tenofovir; Thymidine; Zidovudine

2011
Pharmacokinetics of antiretroviral drugs in anatomical sanctuary sites: the fetal compartment (placenta and amniotic fluid).
    Antiviral therapy, 2011, Volume: 16, Issue:8

    Topics: Adenine; Adult; Amniotic Fluid; Anti-HIV Agents; Cyclohexanes; Enfuvirtide; Female; Fetal Blood; Fetus; HIV Envelope Protein gp41; HIV Fusion Inhibitors; HIV Infections; HIV Integrase Inhibitors; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Maraviroc; Nevirapine; Organophosphonates; Peptide Fragments; Placenta; Pregnancy; Pregnancy Complications, Infectious; Pyrrolidinones; Raltegravir Potassium; Reverse Transcriptase Inhibitors; Tenofovir; Triazoles; Viral Load; Zidovudine

2011
Antiretrovirals for HIV Exposure Prophylaxis.
    Current medicinal chemistry, 2012, Volume: 19, Issue:35

    Topics: Adenine; Anti-HIV Agents; Deoxycytidine; Dideoxynucleosides; Emtricitabine; HIV; HIV Infections; Humans; Lamivudine; Occupational Exposure; Organophosphonates; Stavudine; Tenofovir; Zidovudine

2012

Trials

44 trial(s) available for zidovudine and adenine

ArticleYear
Use of two virustatica (AZT, PMEA) in the treatment of FIV and of FeLV seropositive cats with clinical symptoms.
    Veterinary immunology and immunopathology, 1992, Volume: 35, Issue:1-2

    Topics: Adenine; Animals; Antiviral Agents; Cats; CD4-CD8 Ratio; CD4-Positive T-Lymphocytes; Double-Blind Method; Enzyme-Linked Immunosorbent Assay; Feline Acquired Immunodeficiency Syndrome; Gene Products, gag; Hematocrit; Immunodeficiency Virus, Feline; Injections, Subcutaneous; Leukemia Virus, Feline; Leukemia, Feline; Organophosphonates; T-Lymphocytes, Regulatory; Zidovudine

1992
Genotypic and phenotypic characterization of human immunodeficiency virus type 1 variants isolated from AIDS patients after prolonged adefovir dipivoxil therapy.
    Antimicrobial agents and chemotherapy, 1998, Volume: 42, Issue:7

    Topics: Acquired Immunodeficiency Syndrome; Adenine; Anti-HIV Agents; Drug Resistance, Microbial; Genotype; HIV Reverse Transcriptase; HIV-1; Humans; Mutation; Organophosphonates; Phenotype; Recombination, Genetic; Viral Load; Zidovudine

1998
Human immunodeficiency virus type 1 expressing the lamivudine-associated M184V mutation in reverse transcriptase shows increased susceptibility to adefovir and decreased replication capability in vitro.
    The Journal of infectious diseases, 1999, Volume: 179, Issue:1

    Topics: Adenine; Drug Resistance, Microbial; Drug Therapy, Combination; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; In Vitro Techniques; Lamivudine; Organophosphonates; Point Mutation; Reverse Transcriptase Inhibitors; Virus Replication; Zidovudine

1999
New once-daily HIV combination better tolerated.
    Expert review of anti-infective therapy, 2004, Volume: 2, Issue:6

    Topics: Adenine; Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Deoxycytidine; Drug Administration Schedule; Drug Therapy, Combination; Emtricitabine; HIV Infections; Humans; Lamivudine; Organophosphonates; Oxazines; Tenofovir; Zidovudine

2004
Tenofovir regimen compared with Combivir.
    AIDS patient care and STDs, 2005, Volume: 19, Issue:1

    Topics: Adenine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Combinations; Europe; Female; Follow-Up Studies; HIV Infections; Humans; Lamivudine; Male; Maximum Tolerated Dose; Organophosphonates; Risk Assessment; Severity of Illness Index; Single-Blind Method; Tenofovir; Treatment Outcome; United States; Viral Load; Zidovudine

2005
High virological failure rate in HIV patients after switching to a regimen with two nucleoside reverse transcriptase inhibitors plus tenofovir.
    AIDS (London, England), 2005, Apr-29, Volume: 19, Issue:7

    Topics: Acquired Immunodeficiency Syndrome; Adenine; Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Didanosine; Drug Resistance, Multiple, Viral; Female; Follow-Up Studies; HIV-1; Humans; Male; Middle Aged; Multivariate Analysis; Organophosphonates; Reverse Transcriptase Inhibitors; RNA, Viral; Tenofovir; Treatment Failure; Viral Load; Zidovudine

2005
Tenofovir DF, emtricitabine, and efavirenz vs. zidovudine, lamivudine, and efavirenz for HIV.
    The New England journal of medicine, 2006, Jan-19, Volume: 354, Issue:3

    Topics: Adenine; Adolescent; Adult; Aged; Alkynes; Anti-Retroviral Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Cyclopropanes; Deoxycytidine; Emtricitabine; Female; HIV; HIV Infections; Humans; Lamivudine; Male; Middle Aged; Organophosphonates; Oxazines; Prospective Studies; RNA, Viral; Tenofovir; Zidovudine

2006
An open-label, randomized comparative pilot study of a single-class quadruple therapy regimen versus a 2-class triple therapy regimen for individuals initiating antiretroviral therapy.
    Antiviral therapy, 2006, Volume: 11, Issue:1

    Topics: Adenine; Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Dideoxynucleosides; Drug Therapy, Combination; Female; HIV Infections; Humans; Lamivudine; Male; Organophosphonates; Oxazines; Reverse Transcriptase Inhibitors; Tenofovir; Treatment Outcome; Zidovudine

2006
Virological response to a triple nucleoside/nucleotide analogue regimen over 48 weeks in HIV-1-infected adults in Africa.
    AIDS (London, England), 2006, Jun-26, Volume: 20, Issue:10

    Topics: Adenine; Adolescent; Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Developing Countries; Drug Resistance, Viral; Female; Genotype; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Male; Middle Aged; Mutation; Organophosphonates; RNA, Viral; Tenofovir; Treatment Outcome; Uganda; Viral Load; Zidovudine; Zimbabwe

2006
A randomized comparative trial of tenofovir DF or abacavir as replacement for a thymidine analogue in persons with lipoatrophy.
    AIDS (London, England), 2006, Oct-24, Volume: 20, Issue:16

    Topics: Adenine; Adult; Aged; Anti-HIV Agents; Biomarkers; Body Fat Distribution; Dideoxynucleosides; Female; HIV Infections; HIV-Associated Lipodystrophy Syndrome; Humans; Lipids; Male; Middle Aged; Organophosphonates; Reverse Transcriptase Inhibitors; Stavudine; Tenofovir; Zidovudine

2006
Tenofovir disoproxil fumarate, emtricitabine, and efavirenz versus fixed-dose zidovudine/lamivudine and efavirenz in antiretroviral-naive patients: virologic, immunologic, and morphologic changes--a 96-week analysis.
    Journal of acquired immune deficiency syndromes (1999), 2006, Dec-15, Volume: 43, Issue:5

    Topics: Adenine; Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Deoxycytidine; Drug Resistance, Viral; Emtricitabine; Genotype; HIV Infections; HIV-1; Humans; Lamivudine; Organophosphonates; Oxazines; RNA, Viral; Tenofovir; Time Factors; Viral Load; Zidovudine

2006
Virologic response of zidovudine, lamivudine, and tenofovir disoproxil fumarate combination in antiretroviral-naive HIV-1-infected patients.
    Journal of acquired immune deficiency syndromes (1999), 2006, Dec-15, Volume: 43, Issue:5

    Topics: Adenine; Adult; Aged; Anti-HIV Agents; CD4 Lymphocyte Count; Cohort Studies; Drug Therapy, Combination; Female; HIV Infections; Humans; Lamivudine; Male; Middle Aged; Organophosphonates; Pilot Projects; Tenofovir; Viral Load; Zidovudine

2006
Antiretroviral efficacy and virological profile of a zidovudine/lamivudine/tenofovir disoproxil fumarate combination therapy in antiretroviral-naive patients.
    Antiviral therapy, 2006, Volume: 11, Issue:6

    Topics: Adenine; Anti-HIV Agents; Drug Resistance, Viral; Drug Therapy, Combination; Female; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Male; Mutation; Organophosphonates; Pilot Projects; Reverse Transcriptase Inhibitors; Tenofovir; Treatment Failure; Treatment Outcome; Zidovudine

2006
Tenofovir disoproxil fumarate, emtricitabine, and efavirenz compared with zidovudine/lamivudine and efavirenz in treatment-naive patients: 144-week analysis.
    Journal of acquired immune deficiency syndromes (1999), 2008, Jan-01, Volume: 47, Issue:1

    Topics: Adenine; Adult; Alkynes; Benzoxazines; Cyclopropanes; Deoxycytidine; Drug Resistance, Viral; Drug Therapy, Combination; Emtricitabine; Female; HIV Infections; Humans; Lamivudine; Male; Organophosphonates; Reverse Transcriptase Inhibitors; Tenofovir; Zidovudine

2008
Zidovudine/lamivudine/abacavir plus tenofovir in HIV-infected naive patients: a 96-week prospective one-arm pilot study.
    AIDS research and human retroviruses, 2008, Volume: 24, Issue:7

    Topics: Adenine; Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Dideoxynucleosides; Endpoint Determination; Female; HIV Infections; Humans; Lamivudine; Male; Middle Aged; Organophosphonates; Pilot Projects; Prospective Studies; Spain; Tenofovir; Treatment Outcome; Viral Load; Zidovudine

2008
Endothelial function in human immunodeficiency virus-infected antiretroviral-naive subjects before and after starting potent antiretroviral therapy: The ACTG (AIDS Clinical Trials Group) Study 5152s.
    Journal of the American College of Cardiology, 2008, Aug-12, Volume: 52, Issue:7

    Topics: Adenine; Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Brachial Artery; CD4 Lymphocyte Count; Cyclopropanes; Endothelium, Vascular; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Lopinavir; Male; Organophosphonates; Prospective Studies; Pyrimidinones; Reverse Transcriptase Inhibitors; Ritonavir; Stavudine; Tenofovir; Time Factors; Zidovudine

2008
A randomized trial of combination hepatitis B therapy in HIV/HBV coinfected antiretroviral naïve individuals in Thailand.
    Hepatology (Baltimore, Md.), 2008, Volume: 48, Issue:4

    Topics: Adenine; Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Cyclopropanes; DNA, Viral; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Hepatitis B; Hepatitis B virus; HIV Infections; Humans; Lamivudine; Male; Middle Aged; Organophosphonates; Prospective Studies; Tenofovir; Thailand; Treatment Outcome; Zidovudine

2008
The 3-year renal safety of a tenofovir disoproxil fumarate vs. a thymidine analogue-containing regimen in antiretroviral-naive patients.
    AIDS (London, England), 2008, Oct-18, Volume: 22, Issue:16

    Topics: Adenine; Adolescent; Adult; Aged; Aged, 80 and over; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Creatinine; Double-Blind Method; Female; Glomerular Filtration Rate; HIV Infections; HIV-1; Humans; Male; Middle Aged; Organophosphonates; Phosphorus; Proteinuria; Reverse Transcriptase Inhibitors; Stavudine; Tenofovir; Young Adult; Zidovudine

2008
Improvements in cheek volume in lipoatrophic individuals switching away from thymidine nucleoside reverse transcriptase inhibitors.
    HIV medicine, 2009, Volume: 10, Issue:6

    Topics: Absorptiometry, Photon; Adenine; Adult; Aged; Body Composition; Cheek; Dideoxynucleosides; Female; HIV Infections; HIV-1; HIV-Associated Lipodystrophy Syndrome; Humans; Male; Middle Aged; Organophosphonates; Quality of Life; Reverse Transcriptase Inhibitors; Stavudine; Tenofovir; Zidovudine

2009
Switch from a ZDV/3TC-based regimen to a completely once daily (QD) regimen of emtricitabine/tenofovir DF fixed dose combination plus a third QD agent (SONETT).
    European journal of medical research, 2009, May-14, Volume: 14, Issue:5

    Topics: Adenine; Adult; Aged; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Deoxycytidine; Drug Administration Schedule; Drug Combinations; Emtricitabine; Female; Hemoglobins; HIV Infections; HIV-1; Humans; Lamivudine; Male; Middle Aged; Organophosphonates; Prospective Studies; RNA, Viral; Tenofovir; Treatment Outcome; Viral Load; Young Adult; Zidovudine

2009
A randomized comparative trial of continued zidovudine/lamivudine or replacement with tenofovir disoproxil fumarate/emtricitabine in efavirenz-treated HIV-1-infected individuals.
    Journal of acquired immune deficiency syndromes (1999), 2009, Aug-15, Volume: 51, Issue:5

    Topics: Adenine; Adipose Tissue; Adult; Aged; Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Deoxycytidine; Emtricitabine; Extremities; Female; HIV Infections; HIV-1; HIV-Associated Lipodystrophy Syndrome; Humans; Lamivudine; Lipids; Male; Middle Aged; Organophosphonates; Tenofovir; Young Adult; Zidovudine

2009
Modulation of K65R selection by zidovudine inclusion: analysis of HIV resistance selection in subjects with virologic failure receiving once-daily abacavir/lamivudine/zidovudine and tenofovir DF (study COL40263).
    AIDS research and human retroviruses, 2009, Volume: 25, Issue:7

    Topics: Adenine; Adult; Amino Acid Substitution; Anti-HIV Agents; Dideoxynucleosides; Drug Administration Schedule; Drug Resistance, Multiple, Viral; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Middle Aged; Organophosphonates; Pilot Projects; RNA, Viral; Tenofovir; Treatment Failure; Zidovudine

2009
Development of HIV-1 drug resistance through 144 weeks in antiretroviral-naïve subjects on emtricitabine, tenofovir disoproxil fumarate, and efavirenz compared with lamivudine/zidovudine and efavirenz in study GS-01-934.
    Journal of acquired immune deficiency syndromes (1999), 2009, Oct-01, Volume: 52, Issue:2

    Topics: Adenine; Alkynes; Amino Acid Substitution; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Cyclopropanes; Deoxycytidine; Drug Resistance, Viral; Emtricitabine; Genome, Viral; Genotype; HIV Infections; HIV-1; Humans; Lamivudine; Mutation, Missense; Organophosphonates; Tenofovir; Treatment Failure; Zidovudine

2009
Rates of virological failure in patients treated in a home-based versus a facility-based HIV-care model in Jinja, southeast Uganda: a cluster-randomised equivalence trial.
    Lancet (London, England), 2009, Dec-19, Volume: 374, Issue:9707

    Topics: Adenine; Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Community Health Services; Female; HIV; HIV Infections; Home Care Services; Humans; Lamivudine; Male; Nevirapine; Organophosphonates; Stavudine; Tenofovir; Uganda; Zidovudine

2009
Routine versus clinically driven laboratory monitoring of HIV antiretroviral therapy in Africa (DART): a randomised non-inferiority trial.
    Lancet (London, England), 2010, Jan-09, Volume: 375, Issue:9709

    Topics: Adenine; Adolescent; Adult; Africa; Aged; Anemia; Anti-Retroviral Agents; CD4 Lymphocyte Count; Creatinine; Dideoxynucleosides; Disease Progression; Drug Monitoring; Female; Glomerular Filtration Rate; Hemoglobins; HIV Infections; HIV-1; HIV-Associated Lipodystrophy Syndrome; Humans; Lamivudine; Male; Middle Aged; Neutropenia; Neutrophils; Nevirapine; Organophosphonates; RNA, Viral; Tenofovir; Urea; Viral Load; Zidovudine

2010
Adipocyte differentiation, mitochondrial gene expression and fat distribution: differences between zidovudine and tenofovir after 6 months.
    Antiviral therapy, 2009, Volume: 14, Issue:8

    Topics: Adenine; Adipocytes; Adipose Tissue; Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Cell Differentiation; Cyclopropanes; Drug Therapy, Combination; Fatty Acids; Female; Gene Expression; Genes, Mitochondrial; HIV Infections; HIV-Associated Lipodystrophy Syndrome; Humans; Lamivudine; Male; Mitochondria; Organophosphonates; Reverse Transcriptase Inhibitors; Tenofovir; Up-Regulation; Zidovudine

2009
Population pharmacokinetics of nevirapine in HIV-1-infected pregnant women and their neonates.
    Antimicrobial agents and chemotherapy, 2011, Volume: 55, Issue:1

    Topics: Adenine; Adult; Anti-HIV Agents; Deoxycytidine; Emtricitabine; Female; HIV Infections; Humans; Infant, Newborn; Nevirapine; Organophosphonates; Pregnancy; Tenofovir; Treatment Outcome; Young Adult; Zidovudine

2011
Beliefs about antiretroviral therapy, treatment adherence and quality of life in a 48-week randomised study of continuation of zidovudine/lamivudine or switch to tenofovir DF/emtricitabine, each with efavirenz.
    AIDS care, 2011, Volume: 23, Issue:6

    Topics: Adenine; Adult; Aged; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Cyclopropanes; Deoxycytidine; Drug Combinations; Drug Substitution; Drug Therapy, Combination; Emtricitabine; Female; Health Knowledge, Attitudes, Practice; HIV Infections; HIV-1; Humans; Lamivudine; Male; Medication Adherence; Middle Aged; Organophosphonates; Quality of Life; Tenofovir; Treatment Outcome; Young Adult; Zidovudine

2011
Virological response and resistance profiles after 24 months of first-line antiretroviral treatment in adults living in Bangui, Central African Republic.
    AIDS research and human retroviruses, 2012, Volume: 28, Issue:4

    Topics: Adenine; Adult; Anti-HIV Agents; Atazanavir Sulfate; CD4 Lymphocyte Count; Central African Republic; DNA Fingerprinting; Drug Resistance, Viral; Female; Genetic Variation; Health Services Accessibility; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Lopinavir; Male; Medication Adherence; Oligopeptides; Organophosphonates; Prospective Studies; Pyridines; Reverse Transcriptase Inhibitors; RNA, Viral; Tenofovir; Viral Load; Young Adult; Zidovudine

2012
Glomerular dysfunction and associated risk factors over 4-5 years following antiretroviral therapy initiation in Africa.
    Antiviral therapy, 2011, Volume: 16, Issue:7

    Topics: Adenine; Adult; Africa; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Creatinine; Dideoxynucleosides; Female; Glomerular Filtration Rate; HIV Infections; Humans; Kidney Diseases; Kidney Glomerulus; Lamivudine; Male; Nevirapine; Organophosphonates; Risk Factors; Tenofovir; Time Factors; Zidovudine

2011
Dynamics of cognitive change in HIV-infected individuals commencing three different initial antiretroviral regimens: a randomized, controlled study.
    HIV medicine, 2012, Volume: 13, Issue:4

    Topics: Adenine; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Atazanavir Sulfate; Benzoxazines; Cognition; Cognition Disorders; Cyclopropanes; Deoxycytidine; Dideoxynucleosides; Drug Therapy, Combination; Emtricitabine; HIV Infections; Humans; Male; Oligopeptides; Organophosphonates; Pyridines; Ritonavir; Tenofovir; Zidovudine

2012
Evidence for a shift to anaerobic metabolism in adipose tissue in efavirenz-containing regimens for HIV with different nucleoside backbones.
    Antiviral therapy, 2012, Volume: 17, Issue:3

    Topics: Adenine; Adipose Tissue; Adult; Alkynes; Anaerobiosis; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Drug Therapy, Combination; Electron Transport Complex IV; Female; Gene Expression Regulation; HIV Infections; HIV-1; Humans; Ion Channels; Lipogenesis; Male; Middle Aged; Mitochondrial Proteins; Organophosphonates; Reverse Transcriptase Inhibitors; Tenofovir; Treatment Outcome; Uncoupling Protein 2; Zidovudine

2012
Effect of gender and race on the week 48 findings in treatment-naïve, HIV-1-infected patients enrolled in the randomized, phase III trials ECHO and THRIVE.
    HIV medicine, 2012, Volume: 13, Issue:7

    Topics: Acquired Immunodeficiency Syndrome; Adenine; Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Black or African American; CD4 Lymphocyte Count; Cyclopropanes; Dideoxynucleosides; Double-Blind Method; Drug Administration Schedule; Drug Combinations; Female; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Male; Nitriles; Organophosphonates; Pyrimidines; Rilpivirine; Sex Factors; Tenofovir; Treatment Outcome; Viral Load; Zidovudine

2012
A comparison of measured and estimated glomerular filtration rate in successfully treated HIV-patients with preserved renal function.
    Clinical nephrology, 2012, Volume: 77, Issue:4

    Topics: Adenine; Adult; Anti-HIV Agents; Body Mass Index; Deoxycytidine; Emtricitabine; Female; Glomerular Filtration Rate; HIV Infections; Humans; Lamivudine; Linear Models; Male; Middle Aged; Netherlands; Organophosphonates; Pilot Projects; Research Design; Statistics, Nonparametric; Tenofovir; Treatment Outcome; Zidovudine

2012
Pregnancy and infant outcomes among HIV-infected women taking long-term ART with and without tenofovir in the DART trial.
    PLoS medicine, 2012, Volume: 9, Issue:5

    Topics: Abortion, Spontaneous; Adenine; Adult; Anti-HIV Agents; Body Height; Body Weight; Breast Feeding; Burns; Cause of Death; Child, Preschool; Congenital Abnormalities; Drug Combinations; Female; Follow-Up Studies; Fractures, Bone; Growth; HIV Infections; HIV Seropositivity; Humans; Infant; Infant Mortality; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Male; Measles; Organophosphonates; Pregnancy; Pregnancy Complications, Infectious; Pregnancy Outcome; Prevalence; Respiratory Tract Infections; Tenofovir; Uganda; Zidovudine; Zimbabwe

2012
Biphasic elimination of tenofovir diphosphate and nonlinear pharmacokinetics of zidovudine triphosphate in a microdosing study.
    Journal of acquired immune deficiency syndromes (1999), 2012, Dec-15, Volume: 61, Issue:5

    Topics: Adenine; Adult; Anti-HIV Agents; Biological Availability; Carbon Radioisotopes; CD4-Positive T-Lymphocytes; Dideoxynucleotides; Female; Humans; Male; Mass Spectrometry; Middle Aged; Organophosphonates; Phosphorylation; Reverse Transcriptase Inhibitors; Tenofovir; Thymine Nucleotides; Zidovudine

2012
A 72-week randomized study of the safety and efficacy of a stavudine to zidovudine switch at 24 weeks compared to zidovudine or tenofovir disoproxil fumarate when given with lamivudine and nevirapine.
    Antiviral therapy, 2012, Volume: 17, Issue:8

    Topics: Adenine; Adult; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Diet; Drug Administration Schedule; Drug Substitution; Female; Glomerular Filtration Rate; Hemoglobins; HIV Infections; Humans; Lamivudine; Male; Nevirapine; Organophosphonates; Peripheral Nervous System Diseases; Stavudine; Tenofovir; Treatment Outcome; Viral Load; Zidovudine

2012
Impact of switching from zidovudine to tenofovir disoproxil fumarate on bone mineral density and markers of bone metabolism in virologically suppressed HIV-1 infected patients; a substudy of the PREPARE study.
    The Journal of clinical endocrinology and metabolism, 2013, Volume: 98, Issue:4

    Topics: Adenine; Adult; Anti-HIV Agents; Biomarkers; Bone and Bones; Bone Density; Cohort Studies; Down-Regulation; Drug Substitution; Female; HIV Infections; HIV-1; Humans; Male; Middle Aged; Organophosphonates; Parathyroid Hormone; Tenofovir; Vitamin D; Zidovudine

2013
Pharmacokinetic interactions between lersivirine and zidovudine, tenofovir disoproxil fumarate/emtricitabine and abacavir/lamivudine.
    Antiviral therapy, 2013, Volume: 18, Issue:6

    Topics: Adenine; Adult; Anti-HIV Agents; Deoxycytidine; Dideoxynucleosides; Drug Combinations; Drug Interactions; Emtricitabine; Female; Healthy Volunteers; HIV Infections; Humans; Lamivudine; Male; Middle Aged; Nitriles; Organophosphonates; Pyrazoles; Tenofovir; Young Adult; Zidovudine

2013
Early upper digestive tract side effects of zidovudine with tenofovir plus emtricitabine in West African adults with high CD4 counts.
    Journal of the International AIDS Society, 2013, Apr-30, Volume: 16

    Topics: Adenine; Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Cote d'Ivoire; Deoxycytidine; Drug Therapy, Combination; Drug-Related Side Effects and Adverse Reactions; Emtricitabine; Female; Gastrointestinal Diseases; HIV Infections; Humans; Male; Middle Aged; Organophosphonates; Tenofovir; Zidovudine

2013
Phenotypic and genotypic analyses to guide selection of reverse transcriptase inhibitors in second-line HIV therapy following extended virological failure in Uganda.
    The Journal of antimicrobial chemotherapy, 2014, Volume: 69, Issue:7

    Topics: Adenine; Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Drug Resistance, Viral; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Inhibitory Concentration 50; Microbial Sensitivity Tests; Organophosphonates; Tenofovir; Uganda; Zidovudine

2014
First-line antiretroviral therapy with nevirapine versus lopinavir-ritonavir based regimens in a resource-limited setting.
    AIDS (London, England), 2014, May-15, Volume: 28, Issue:8

    Topics: Adenine; Adult; CD4 Lymphocyte Count; Deoxycytidine; Drug Resistance, Viral; Drug Therapy, Combination; Emtricitabine; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Lopinavir; Male; Middle Aged; Nevirapine; Organophosphonates; Reverse Transcriptase Inhibitors; Ritonavir; RNA, Viral; Tenofovir; Treatment Outcome; Viral Load; Zidovudine

2014
A randomized, open-label study of the safety and efficacy of switching stavudine or zidovudine to tenofovir disoproxil fumarate in HIV-1-infected children with virologic suppression.
    The Pediatric infectious disease journal, 2015, Volume: 34, Issue:4

    Topics: Adenine; Adolescent; Anti-HIV Agents; Child; Child, Preschool; Drug-Related Side Effects and Adverse Reactions; Female; HIV Infections; HIV-1; Humans; Male; Organophosphonates; RNA, Viral; Stavudine; Tenofovir; Treatment Outcome; Viral Load; Zidovudine

2015
Dual treatment with atazanavir-ritonavir plus lamivudine versus triple treatment with atazanavir-ritonavir plus two nucleos(t)ides in virologically stable patients with HIV-1 (SALT): 48 week results from a randomised, open-label, non-inferiority trial.
    The Lancet. Infectious diseases, 2015, Volume: 15, Issue:7

    Topics: Adenine; Adult; Anti-HIV Agents; Atazanavir Sulfate; Deoxycytidine; Drug Substitution; Drug Therapy, Combination; Emtricitabine; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Male; Middle Aged; Oligopeptides; Organophosphonates; Pyridines; Reverse Transcriptase Inhibitors; Ritonavir; RNA, Viral; Tenofovir; Viral Load; Zidovudine

2015

Other Studies

123 other study(ies) available for zidovudine and adenine

ArticleYear
Threshold interaction energy of NRTI's (2'-deoxy 3'-substituted nucleosidic analogs of reverse transcriptase inhibitors) to undergo competitive inhibition.
    Bioorganic & medicinal chemistry letters, 2004, May-17, Volume: 14, Issue:10

    Topics: Anti-HIV Agents; Binding, Competitive; Inhibitory Concentration 50; Models, Molecular; Nucleosides; Protein Binding; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Thermodynamics

2004
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Different pattern of activity of inhibitors of the human immunodeficiency virus in lymphocytes and monocyte/macrophages.
    Antiviral research, 1992, Volume: 17, Issue:4

    Topics: Adenine; Antibodies, Viral; Antiviral Agents; Benzodiazepines; CD4 Antigens; Cytokines; Didanosine; Doxorubicin; Drug Interactions; HIV; HIV Infections; Humans; Imidazoles; Leukocytes, Mononuclear; Lymphocytes; Macrophages; Monocytes; Organ Specificity; Organophosphonates; Zalcitabine; Zidovudine

1992
[Anti-retroviral activity and molecular-biochemical action mechanism of 2',3'-dideoxynucleoside analogs and 9-(2-phosphonylmethoxyethyl) purine derivatives].
    Verhandelingen - Koninklijke Academie voor Geneeskunde van Belgie, 1991, Volume: 53, Issue:1

    Topics: Adenine; Antiviral Agents; Humans; Phosphorylation; Pyrimidine Nucleosides; Retroviridae; Ribavirin; Structure-Activity Relationship; Zalcitabine; Zidovudine

1991
Inhibitory effects of acyclic nucleoside phosphonate analogs, including (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine, on Epstein-Barr virus replication.
    Antimicrobial agents and chemotherapy, 1991, Volume: 35, Issue:11

    Topics: Adenine; Antiviral Agents; DNA Replication; DNA, Viral; Drug Synergism; Genome, Viral; Herpesvirus 4, Human; Organophosphorus Compounds; Structure-Activity Relationship; Virus Replication; Zidovudine

1991
Transplacental antiretroviral therapy with 9-(2-phosphonylmethoxyethyl)adenine is embryotoxic in transgenic mice.
    Journal of acquired immune deficiency syndromes, 1991, Volume: 4, Issue:9

    Topics: Adenine; Animals; Antiviral Agents; Embryo, Mammalian; Female; Fetal Resorption; Litter Size; Maternal-Fetal Exchange; Mice; Mice, Inbred C57BL; Mice, Transgenic; Moloney murine leukemia virus; Organophosphonates; Pregnancy; Viremia; Zidovudine

1991
Suppression of feline immunodeficiency virus infection in vivo by 9-(2-phosphonomethoxyethyl)adenine.
    Proceedings of the National Academy of Sciences of the United States of America, 1990, Volume: 87, Issue:8

    Topics: Adenine; Animals; Antiviral Agents; Cats; Cell Line; HIV; Immunologic Deficiency Syndromes; Opportunistic Infections; Organophosphonates; Retroviridae; Retroviridae Infections; T-Lymphocytes; Virus Replication; Zidovudine

1990
Inhibition of herpes simplex virus DNA polymerase by diphosphates of acyclic phosphonylmethoxyalkyl nucleotide analogues.
    Antiviral research, 1990, Volume: 13, Issue:5

    Topics: Acyclovir; Adenine; Antiviral Agents; Arabinofuranosylcytosine Triphosphate; Dideoxynucleotides; DNA Polymerase I; DNA Polymerase II; DNA Replication; HeLa Cells; Humans; Kinetics; Nucleic Acid Synthesis Inhibitors; Organophosphonates; Organophosphorus Compounds; Simplexvirus; Thymine Nucleotides; Zidovudine

1990
Inhibitory effects of potent inhibitors of human immunodeficiency virus and cytomegalovirus on the growth of human granulocyte-macrophage progenitor cells in vitro.
    European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 1990, Volume: 9, Issue:8

    Topics: Adenine; Adult; Antiviral Agents; Bone Marrow; Bone Marrow Cells; Cells, Cultured; Cidofovir; Cytomegalovirus; Cytosine; Foscarnet; Ganciclovir; Granulocytes; Hematopoietic Stem Cells; HIV; Humans; Macrophages; Organophosphonates; Organophosphorus Compounds; Phosphonoacetic Acid; Zidovudine

1990
Inhibitory effects of 9-(2-phosphonylmethoxyethyl)adenine and 3'-azido-2',3'-dideoxythymidine on tumor development in mice inoculated intracerebrally with Moloney murine sarcoma virus.
    International journal of cancer, 1990, Mar-15, Volume: 45, Issue:3

    Topics: Adenine; Animals; Brain Neoplasms; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Evaluation, Preclinical; Mice; Moloney murine sarcoma virus; Organophosphonates; Sarcoma, Experimental; Skull Neoplasms; Zidovudine

1990
Anti-retrovirus activity of 9-(2-phosphonylmethoxyethyl)adenine (PMEA) in vivo increases when it is less frequently administered.
    International journal of cancer, 1990, Aug-15, Volume: 46, Issue:2

    Topics: Adenine; Animals; Antiviral Agents; Cell Transformation, Viral; Cytopathogenic Effect, Viral; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; HIV-1; Mice; Mice, Inbred C3H; Moloney murine sarcoma virus; Neoplasm Transplantation; Organophosphonates; Retroviridae; Sarcoma, Experimental; Time Factors; Zidovudine

1990
An in vitro system for screening anti-hepatitis B virus drugs.
    Virology, 1989, Volume: 169, Issue:1

    Topics: Acyclovir; Adenine; Antiviral Agents; Blotting, Southern; Carcinoma, Hepatocellular; Cytarabine; Dideoxyadenosine; Dideoxynucleosides; DNA Replication; DNA, Viral; Hepatitis B virus; Humans; Interferons; Liver Neoplasms; Tumor Cells, Cultured; Vidarabine; Virus Replication; Zalcitabine; Zidovudine

1989
Susceptibility of human immunodeficiency virus type 1 replication in vitro to acyclic adenosine analogs and synergy of the analogs with 3'-azido-3'-deoxythymidine.
    Antimicrobial agents and chemotherapy, 1989, Volume: 33, Issue:9

    Topics: Adenine; Adenosine; Animals; Antiviral Agents; Dideoxynucleotides; Drug Synergism; HIV-1; Organophosphonates; Reverse Transcriptase Inhibitors; T-Lymphocytes; Thymine Nucleotides; Virus Replication; Zidovudine

1989
9-(2-Phosphonylmethoxyethyl)adenine in the treatment of murine acquired immunodeficiency disease and opportunistic herpes simplex virus infections.
    Antimicrobial agents and chemotherapy, 1989, Volume: 33, Issue:11

    Topics: Acquired Immunodeficiency Syndrome; Adenine; Animals; Antiviral Agents; Concanavalin A; Herpes Simplex; Interferons; Mice; Mice, Inbred C57BL; Mitogens; Opportunistic Infections; Organophosphonates; Spleen; Zidovudine

1989
Comparative efficacy of broad-spectrum antiviral agents as inhibitors of African swine fever virus replication in vitro.
    Antiviral research, 1987, Volume: 7, Issue:3

    Topics: Adenine; African Swine Fever Virus; Amides; Animals; Antiviral Agents; Dose-Response Relationship, Drug; Iridoviridae; Organophosphonates; Organophosphorus Compounds; Pyrazoles; Ribavirin; Ribonucleosides; Ribose; Thymidine; Tubercidin; Vero Cells; Virus Replication; Zidovudine

1987
Susceptibilities of zidovudine-resistant variants of human immunodeficiency virus type 1 to inhibition by acyclic nucleoside phosphonates.
    Antimicrobial agents and chemotherapy, 1994, Volume: 38, Issue:7

    Topics: Adenine; Antiviral Agents; Cell Line; Drug Resistance, Microbial; HIV-1; Humans; Molecular Structure; Organophosphonates; Organophosphorus Compounds; T-Lymphocytes; Zidovudine

1994
Intracellular delivery of nucleoside monophosphates through a reductase-mediated activation process.
    Antiviral research, 1993, Volume: 22, Issue:2-3

    Topics: Adenine; Antiviral Agents; B-Lymphocytes; Cell Line; Dideoxynucleosides; Dideoxynucleotides; Esters; HIV-1; Humans; Organophosphonates; Oxidoreductases; Prodrugs; T-Lymphocytes; Thymine Nucleotides; Uridine Monophosphate; Zidovudine

1993
The effect of purine phosphonomethoxyalkyl derivatives on DNA synthesis in CHO Chinese hamster cells.
    Neoplasma, 1993, Volume: 40, Issue:6

    Topics: Adenine; Animals; Antiviral Agents; CHO Cells; Cricetinae; Cricetulus; Cytarabine; DNA Damage; DNA Replication; Dose-Response Relationship, Drug; Guanine; Organophosphonates; Organophosphorus Compounds; Zidovudine

1993
MDL 74,968, a new acyclonucleotide analog: activity against human immunodeficiency virus in vitro and in the hu-PBL-SCID.beige mouse model of infection.
    Antimicrobial agents and chemotherapy, 1996, Volume: 40, Issue:5

    Topics: Adenine; Animals; Antiviral Agents; Cell Line; Cells, Cultured; Didanosine; DNA, Viral; Guanine; HIV Infections; HIV-1; HIV-2; Humans; Male; Mice; Mice, SCID; Monocytes; Organophosphonates; Spleen; T-Lymphocytes; Zidovudine

1996
Comparative kinetic analyses of interaction of inhibitors with Rauscher murine leukemia virus and human immunodeficiency virus reverse transcriptases.
    Antimicrobial agents and chemotherapy, 1996, Volume: 40, Issue:5

    Topics: Adenine; Antiviral Agents; HIV Reverse Transcriptase; HIV-1; Kinetics; Organophosphonates; Phosphates; Rauscher Virus; Reverse Transcriptase Inhibitors; Stavudine; Virus Replication; Zidovudine

1996
Prevention of murine AIDS development by (R)-9-(2-phosphonylmethoxypropyl)adenine.
    Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association, 1998, Aug-01, Volume: 18, Issue:4

    Topics: Adenine; Animals; Anti-HIV Agents; Cell Survival; Clone Cells; Female; Leukemia Virus, Murine; Lymph Nodes; Lymphocyte Activation; Mice; Mice, Inbred C57BL; Murine Acquired Immunodeficiency Syndrome; Organophosphonates; Organophosphorus Compounds; Specific Pathogen-Free Organisms; Spleen; Tenofovir; Virus Replication; Zidovudine

1998
Enhanced 9-(2-phosphonylmethoxyethyl)adenine secretion by a specific, indomethacin-sensitive efflux pump in a mutant 9-(2-phosphonylmethoxyethyl)adenine-resistant human erythroleukemia K562 cell line.
    Molecular pharmacology, 1998, Volume: 54, Issue:5

    Topics: Adenine; Adenine Nucleotides; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antimetabolites; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Biological Transport; Cycloheximide; Dactinomycin; Drug Resistance, Neoplasm; Extracellular Space; Flow Cytometry; Humans; Immunoblotting; Indomethacin; K562 Cells; Mice; Multidrug Resistance-Associated Proteins; Mutation; Organophosphonates; Prodrugs; Protein Synthesis Inhibitors; Sensitivity and Specificity; Temperature; Zidovudine

1998
Correlation of anti-HIV activity with structure: use of electrostatic potential and conformational analysis.
    Bioorganic & medicinal chemistry letters, 1999, Jul-19, Volume: 9, Issue:14

    Topics: Adenine; Anti-HIV Agents; Computer Simulation; Deoxyribonucleotides; Dideoxynucleosides; Hydrogen Bonding; Isomerism; Models, Chemical; Models, Molecular; Static Electricity; Structure-Activity Relationship; Zidovudine

1999
MRP4: A previously unidentified factor in resistance to nucleoside-based antiviral drugs.
    Nature medicine, 1999, Volume: 5, Issue:9

    Topics: Adenine; Anti-HIV Agents; Carrier Proteins; Cell Line; Drug Resistance, Microbial; Gene Amplification; Gene Dosage; Gene Expression; Genes, Dominant; HIV-1; Humans; Hybrid Cells; Inhibitory Concentration 50; Membrane Transport Proteins; Nucleosides; Organophosphonates; Phenotype; Reverse Transcriptase Inhibitors; RNA, Messenger; T-Lymphocytes; Zidovudine

1999
[Adsorption of derivatives of nucleic acid components on electrodes].
    Sbornik lekarsky, 1998, Volume: 99, Issue:4

    Topics: Adenine; Adsorption; Electric Impedance; Electrochemistry; Electrodes; Nucleosides; Xanthines; Zidovudine

1998
CDC to revisit AZT, post-exposure guidelines. Centers for Disease Control and Prevention.
    AIDS alert, 1996, Volume: 11, Issue:1

    Topics: Adenine; Antiviral Agents; Blood-Borne Pathogens; Centers for Disease Control and Prevention, U.S.; Guidelines as Topic; Health Personnel; HIV Infections; Humans; Macaca; Needlestick Injuries; Occupational Exposure; Organophosphonates; Zidovudine

1996
Update on other antivirals.
    PI perspective, 1996, Issue:no 18

    Topics: Adenine; Antiviral Agents; Didanosine; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Organophosphonates; Stavudine; Zalcitabine; Zidovudine

1996
Scientific basis for PEP rests in animal trials.
    AIDS alert, 1997, Volume: 12, Issue:9

    Topics: Adenine; Animals; Anti-HIV Agents; Centers for Disease Control and Prevention, U.S.; Health Personnel; HIV; HIV Infections; Humans; Macaca; Nevirapine; Occupational Diseases; Organophosphonates; Organophosphorus Compounds; Pan troglodytes; Pyridines; Reverse Transcriptase Inhibitors; Simian Immunodeficiency Virus; Tenofovir; United States; Zidovudine

1997
New drugs on the horizon.
    Project Inform perspective, 1998, Issue:24

    Topics: Adenine; Alkynes; Anti-HIV Agents; Benzoxazines; Carbamates; Clinical Trials as Topic; Cyclopropanes; Dideoxynucleosides; Drug Therapy, Combination; Furans; HIV Infections; HIV Protease Inhibitors; Humans; Lamivudine; Oxazines; Reverse Transcriptase Inhibitors; Sulfonamides; United States; Zidovudine

1998
Tenofovir, adefovir, and zidovudine susceptibilities of primary human immunodeficiency virus type 1 isolates with non-B subtypes or nucleoside resistance.
    AIDS research and human retroviruses, 2001, Aug-10, Volume: 17, Issue:12

    Topics: Adenine; Anti-HIV Agents; Drug Resistance, Microbial; HIV Infections; HIV-1; Humans; Microbial Sensitivity Tests; Organophosphonates; Organophosphorus Compounds; Reverse Transcriptase Inhibitors; Tenofovir; Zidovudine

2001
Tenofovir exhibits low cytotoxicity in various human cell types: comparison with other nucleoside reverse transcriptase inhibitors.
    Antiviral research, 2002, Volume: 54, Issue:1

    Topics: Adenine; Anti-HIV Agents; Antigens, CD34; Cell Line; Didanosine; Dideoxynucleosides; Epithelial Cells; Hematopoietic Stem Cells; Humans; Kidney Tubules, Proximal; Liver; Muscle, Skeletal; Organophosphonates; Organophosphorus Compounds; Reverse Transcriptase Inhibitors; Stavudine; Tenofovir; Tumor Cells, Cultured; Zalcitabine; Zidovudine

2002
ATP-dependent removal of nucleoside reverse transcriptase inhibitors by human immunodeficiency virus type 1 reverse transcriptase.
    Antimicrobial agents and chemotherapy, 2002, Volume: 46, Issue:7

    Topics: Adenine; Adenosine Triphosphate; Anti-HIV Agents; Catalysis; Drug Resistance, Viral; HIV Reverse Transcriptase; Mutation; Organophosphonates; Organophosphorus Compounds; Recombinant Proteins; Reverse Transcriptase Inhibitors; Stavudine; Tenofovir; Virus Replication; Zidovudine

2002
Highlights of the 41st Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC).
    The Body positive, 2002, Volume: 15, Issue:3

    Topics: Adenine; Antiretroviral Therapy, Highly Active; Dideoxynucleosides; Drug Administration Schedule; Drug Combinations; Drug Resistance, Microbial; Drug Therapy; Epoetin Alfa; Erythropoietin; Hepatitis C; HIV Infections; Humans; Lamivudine; Organophosphonates; Organophosphorus Compounds; Recombinant Proteins; Saquinavir; Tenofovir; Zidovudine

2002
Inhibition of murine AIDS by a heterodinucleotide of azidothymidine and 9-(R)-2-(phosphonomethoxypropyl)adenine.
    The Journal of antimicrobial chemotherapy, 2002, Volume: 50, Issue:5

    Topics: Adenine; Animals; Area Under Curve; Chemistry, Pharmaceutical; Drug Combinations; Mice; Mice, Inbred ICR; Murine Acquired Immunodeficiency Syndrome; Organophosphonates; Organophosphorus Compounds; Prodrugs; Tenofovir; Zidovudine

2002
Metabolic activation of nucleoside and nucleotide reverse transcriptase inhibitors in dendritic and Langerhans cells.
    AIDS (London, England), 2002, Nov-08, Volume: 16, Issue:16

    Topics: Adenine; Anti-HIV Agents; Cell Line; Cells, Cultured; Dendritic Cells; Humans; Lamivudine; Langerhans Cells; Organophosphonates; Organophosphorus Compounds; Phenotype; Reverse Transcriptase Inhibitors; T-Lymphocytes; Tenofovir; Zidovudine

2002
HIV-1 resistance profile of the novel nucleoside reverse transcriptase inhibitor beta-D-2',3'-dideoxy-2',3'-didehydro-5-fluorocytidine (Reverset).
    Antiviral chemistry & chemotherapy, 2003, Volume: 14, Issue:1

    Topics: Adenine; Anti-HIV Agents; Cell Line; Cytidine Triphosphate; Didanosine; Drug Resistance, Multiple, Viral; Genotype; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Mutation; Organophosphonates; Organophosphorus Compounds; Reverse Transcriptase Inhibitors; Species Specificity; Tenofovir; Transfection; Zalcitabine; Zidovudine

2003
Susceptibility of human T cell leukemia virus type I to nucleoside reverse transcriptase inhibitors.
    The Journal of infectious diseases, 2003, Aug-01, Volume: 188, Issue:3

    Topics: Adenine; Cell Line; Dideoxynucleosides; Human T-lymphotropic virus 1; Humans; Lamivudine; Microbial Sensitivity Tests; Organophosphonates; Organophosphorus Compounds; Reverse Transcriptase Inhibitors; Stavudine; Tenofovir; Virus Replication; Zalcitabine; Zidovudine

2003
Inhibition of HIV-1 replication in macrophages by red blood cell-mediated delivery of a heterodinucleotide of azidothymidine and 9-(R)-2-(phosphono methoxypropyl)adenine.
    Antiviral chemistry & chemotherapy, 2001, Volume: 12, Issue:3

    Topics: Adenine; Anti-HIV Agents; Cell Adhesion; Chromatography, High Pressure Liquid; Dideoxynucleotides; Drug Delivery Systems; Drug Stability; Erythrocytes; HIV-1; Humans; In Vitro Techniques; Macrophages; Virus Replication; Zidovudine

2001
Mechanistic basis for reduced viral and enzymatic fitness of HIV-1 reverse transcriptase containing both K65R and M184V mutations.
    The Journal of biological chemistry, 2004, Jan-02, Volume: 279, Issue:1

    Topics: Adenine; Amino Acid Substitution; Anti-HIV Agents; Binding Sites; Drug Resistance, Viral; HIV Reverse Transcriptase; HIV-1; Humans; Models, Molecular; Mutagenesis, Site-Directed; Organophosphonates; Organophosphorus Compounds; Phenotype; Protein Conformation; Recombinant Proteins; Tenofovir; Zidovudine

2004
Synthesis and antiviral activity of novel C-methyl branched cyclopropyl nucleosides.
    Archives of pharmacal research, 2003, Volume: 26, Issue:9

    Topics: Adenine; Antiviral Agents; Crystallography, X-Ray; Cyclization; Cyclopropanes; Cytomegalovirus; Cytotoxicity Tests, Immunologic; Ganciclovir; Herpesvirus 1, Human; HIV-1; Korea; Magnetic Resonance Spectroscopy; Methylation; Molecular Structure; Purine Nucleosides; Purines; Ribavirin; Zidovudine

2003
Studies of molecular mechanism of tenofovir against 3TC- and AZT-resistance mutant HIV-1 reverse transcriptase.
    Bioorganic & medicinal chemistry letters, 2003, Nov-17, Volume: 13, Issue:22

    Topics: Adenine; Amino Acid Sequence; Drug Resistance, Viral; HIV Reverse Transcriptase; Humans; Lamivudine; Models, Molecular; Mutagenesis, Site-Directed; Organophosphonates; Organophosphorus Compounds; Protein Conformation; Reverse Transcriptase Inhibitors; Tenofovir; Zidovudine

2003
Phenotypic impact of HIV reverse transcriptase M184I/V mutations in combination with single thymidine analog mutations on nucleoside reverse transcriptase inhibitor resistance.
    AIDS (London, England), 2004, Aug-20, Volume: 18, Issue:12

    Topics: Adenine; Algorithms; Anti-HIV Agents; Databases, Genetic; Didanosine; Dideoxynucleosides; Drug Resistance, Multiple, Viral; HIV; HIV Infections; Humans; Mutation; Organophosphonates; Organophosphorus Compounds; Phenotype; Reverse Transcriptase Inhibitors; Stavudine; Tenofovir; Thymidine; Zalcitabine; Zidovudine

2004
Multidrug resistance protein 4 (ABCC4)-mediated ATP hydrolysis: effect of transport substrates and characterization of the post-hydrolysis transition state.
    The Journal of biological chemistry, 2004, Nov-19, Volume: 279, Issue:47

    Topics: Adenine; Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Beryllium; Biological Transport; Catalysis; Cations; Cell Line; Cell Membrane; Chelating Agents; Cobalt; Dinoprostone; DNA, Complementary; Dose-Response Relationship, Drug; Edetic Acid; Fluorides; Humans; Hydrolysis; Insecta; Kinetics; Magnesium; Manganese; Methotrexate; Models, Biological; Multidrug Resistance-Associated Proteins; Nucleotides; Organophosphonates; Protein Binding; Substrate Specificity; Vanadates; Zidovudine

2004
The HIV-1 nucleoside reverse transcriptase inhibitors stavudine and zidovudine alter adipocyte functions in vitro.
    AIDS (London, England), 2004, Nov-05, Volume: 18, Issue:16

    Topics: 3T3-L1 Cells; Adenine; Adipocytes; Animals; Apoptosis; Cell Differentiation; Didanosine; Dideoxynucleosides; HIV-1; HIV-Associated Lipodystrophy Syndrome; Lamivudine; Lipid Metabolism; Mice; Mitochondria; Organophosphonates; Reverse Transcriptase Inhibitors; Stavudine; Tenofovir; Zidovudine

2004
Low rate of treatment failure on antiretroviral therapy with tenofovir, lamivudine and zidovudine.
    AIDS (London, England), 2005, Jan-03, Volume: 19, Issue:1

    Topics: Adenine; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Lamivudine; Organophosphonates; Retrospective Studies; Reverse Transcriptase Inhibitors; RNA, Viral; Tenofovir; Treatment Failure; Zidovudine

2005
Meeting notes from ICAAC. Tenofovir + emtricitabine vs. AZT + 3TC.
    AIDS clinical care, 2005, Volume: 17, Issue:1

    Topics: Adenine; CD4 Lymphocyte Count; Deoxycytidine; Emtricitabine; HIV Infections; Humans; Lamivudine; Organophosphonates; Reverse Transcriptase Inhibitors; Tenofovir; Viral Load; Zidovudine

2005
Switching from protease inhibitors to a single-class regimen of abacavir/lamivudine/zidovudine plus tenofovir in patients with HIV load suppression.
    AIDS (London, England), 2005, May-20, Volume: 19, Issue:8

    Topics: Adenine; Adult; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Dideoxynucleosides; Female; HIV Infections; HIV Protease Inhibitors; Humans; Lamivudine; Male; Organophosphonates; Reverse Transcriptase Inhibitors; Tenofovir; Viral Load; Zidovudine

2005
The use of a triple nucleoside-nucleotide regimen for nonoccupational HIV post-exposure prophylaxis.
    HIV medicine, 2005, Volume: 6, Issue:3

    Topics: Adenine; Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Chi-Square Distribution; HIV Infections; Humans; Lamivudine; Male; Nelfinavir; Organophosphonates; Reverse Transcriptase Inhibitors; Risk Assessment; Risk-Taking; Stavudine; Tenofovir; Zidovudine

2005
Adherence to trizivir and tenofovir as a simplified salvage regimen is associated with suppression of viraemia and a decreased cholesterol.
    The Journal of antimicrobial chemotherapy, 2005, Volume: 56, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Adenine; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Cholesterol; Dideoxynucleosides; Drug Combinations; Erythrocyte Indices; Humans; Lamivudine; Organophosphonates; Patient Compliance; Salvage Therapy; Tenofovir; Viral Load; Viremia; Zidovudine

2005
Virological response to HIV-1 nucleoside/nucleotide reverse transcriptase inhibitors-based, tenofovir DF-including regimens in the ANRS Aquitaine Cohort.
    Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2006, Volume: 36, Issue:2

    Topics: Adenine; Cohort Studies; Didanosine; Dideoxynucleosides; Drug Therapy, Combination; France; HIV Infections; HIV Reverse Transcriptase; HIV-1; Hospitals, University; Humans; Lamivudine; Mutation; Organophosphonates; Retrospective Studies; Reverse Transcriptase Inhibitors; Species Specificity; Tenofovir; Treatment Outcome; Viral Load; Zidovudine

2006
The K65R mutation in human immunodeficiency virus type 1 reverse transcriptase exhibits bidirectional phenotypic antagonism with thymidine analog mutations.
    Journal of virology, 2006, Volume: 80, Issue:10

    Topics: Adenine; Amino Acid Substitution; Anti-HIV Agents; Arginine; Didanosine; Dideoxynucleosides; Drug Resistance, Multiple, Viral; Genotype; HIV Reverse Transcriptase; HIV-1; Humans; Lysine; Organophosphonates; Phenotype; Point Mutation; Reverse Transcriptase Inhibitors; Tenofovir; Thymidine; Zalcitabine; Zidovudine

2006
Relationship between antiretrovirals used as part of a cART regimen and CD4 cell count increases in patients with suppressed viremia.
    AIDS (London, England), 2006, May-12, Volume: 20, Issue:8

    Topics: Adenine; Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Middle Aged; Organophosphonates; Prospective Studies; Reverse Transcriptase Inhibitors; Tenofovir; Viral Load; Viremia; Zidovudine

2006
Tenofovir DF and emtricitabine vs. zidovudine and lamivudine.
    The New England journal of medicine, 2006, Jun-08, Volume: 354, Issue:23

    Topics: Adenine; Anti-Retroviral Agents; Bias; Data Interpretation, Statistical; Deoxycytidine; Emtricitabine; HIV Infections; Humans; Lamivudine; Organophosphonates; Research Design; Tenofovir; Zidovudine

2006
Tenofovir DF and emtricitabine vs. zidovudine and lamivudine.
    The New England journal of medicine, 2006, Jun-08, Volume: 354, Issue:23

    Topics: Adenine; Bone Density; Deoxycytidine; Drug Resistance, Viral; Emtricitabine; HIV; HIV Infections; Humans; Lamivudine; Mutation; Organophosphonates; Reverse Transcriptase Inhibitors; Tenofovir; Zidovudine

2006
Rapid improvement of liver function in a patient with HIV and hepatitis B coinfection treated with lamivudine and tenofovir.
    Infection, 2006, Volume: 34, Issue:4

    Topics: Adenine; Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Female; Hepatitis; HIV Infections; Humans; Lamivudine; Liver Function Tests; Organophosphonates; Tenofovir; Zidovudine

2006
In vitro cytotoxicity and mitochondrial toxicity of tenofovir alone and in combination with other antiretrovirals in human renal proximal tubule cells.
    Antimicrobial agents and chemotherapy, 2006, Volume: 50, Issue:11

    Topics: Adenine; Anti-HIV Agents; Cell Survival; Cells, Cultured; Didanosine; DNA, Mitochondrial; Drug Interactions; Electron Transport Complex IV; Humans; Kidney Tubules, Proximal; Lopinavir; Mitochondria; Organophosphonates; Pyrimidinones; Ritonavir; RNA; Tenofovir; Zidovudine

2006
Molecular mechanism by which the K70E mutation in human immunodeficiency virus type 1 reverse transcriptase confers resistance to nucleoside reverse transcriptase inhibitors.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:1

    Topics: Adenine; Amino Acid Substitution; Anti-HIV Agents; Cytidine Triphosphate; Dideoxynucleosides; Dideoxynucleotides; Drug Resistance, Multiple, Viral; Genotype; Glutamic Acid; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Lysine; Mutagenesis, Site-Directed; Organophosphonates; Phenotype; Reverse Transcriptase Inhibitors; Tenofovir; Thymine Nucleotides; Zidovudine

2007
Rate of virologic failure and selection of drug resistance mutations using different triple nucleos(t)ide analogue combinations in HIV-infected patients.
    AIDS research and human retroviruses, 2006, Volume: 22, Issue:12

    Topics: Adenine; Adult; Anti-Retroviral Agents; Drug Resistance, Viral; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Male; Middle Aged; Organophosphonates; Proportional Hazards Models; Retrospective Studies; Reverse Transcriptase Inhibitors; Tenofovir; Treatment Failure; Viral Load; Zidovudine

2006
Anti-HIV agents. Low rate of early virologic failure seen with a combination of Trizivir and tenofovir.
    TreatmentUpdate, 2004, Volume: 16, Issue:2

    Topics: Adenine; Dideoxynucleosides; Drug Combinations; Drug Therapy, Combination; HIV Infections; Humans; Lamivudine; Organophosphonates; Tenofovir; Viral Load; Zidovudine

2004
Progressive multifocal leukoencephalopathy: serial high-b-value diffusion-weighted MR imaging and apparent diffusion coefficient measurements to assess response to highly active antiretroviral therapy.
    AJNR. American journal of neuroradiology, 2007, Volume: 28, Issue:2

    Topics: Acquired Immunodeficiency Syndrome; Adenine; Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Brain; Diffusion; Diffusion Magnetic Resonance Imaging; HIV Protease Inhibitors; Humans; Leukoencephalopathy, Progressive Multifocal; Lopinavir; Male; Organophosphonates; Pyrimidinones; Ritonavir; Tenofovir; Zidovudine

2007
Evidence and possible consequences of the phosphorylation of nucleoside reverse transcriptase inhibitors in human red blood cells.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:6

    Topics: Adenine; Anti-HIV Agents; Drug Interactions; Drug Therapy, Combination; Erythrocytes; HIV Infections; Humans; Lamivudine; Nucleosides; Organophosphonates; Phosphorylation; Reverse Transcriptase Inhibitors; Tenofovir; Treatment Outcome; Zidovudine

2007
Selective inhibition of porcine endogenous retrovirus replication in human cells by acyclic nucleoside phosphonates.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:7

    Topics: Adenine; Amino Acid Sequence; Animals; Antiviral Agents; Catalysis; Cell Line; Dose-Response Relationship, Drug; Endogenous Retroviruses; HIV-1; Humans; Kidney; Molecular Sequence Data; Organophosphonates; Polymerase Chain Reaction; Protein Structure, Tertiary; Reverse Transcriptase Inhibitors; Stavudine; Swine; Swine, Miniature; Tenofovir; Virus Replication; Zidovudine

2007
Effects of the translocation status of human immunodeficiency virus type 1 reverse transcriptase on the efficiency of excision of tenofovir.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:8

    Topics: Adenine; Adenosine Triphosphate; Anti-HIV Agents; Base Sequence; Drug Resistance, Viral; HIV Reverse Transcriptase; HIV-1; Humans; Kinetics; Microbial Sensitivity Tests; Molecular Sequence Data; Organophosphonates; Reverse Transcriptase Inhibitors; Tenofovir; Zidovudine

2007
Assessment of adverse events associated with antiretroviral regimens for postexposure prophylaxis for occupational and nonoccupational exposures to prevent transmission of human immunodeficiency virus.
    Infection control and hospital epidemiology, 2007, Volume: 28, Issue:6

    Topics: Adenine; Adult; Anti-HIV Agents; Chemoprevention; Drug Combinations; Female; HIV Infections; Humans; Lamivudine; Logistic Models; Male; Middle Aged; New York; Occupational Exposure; Occupational Health Services; Organophosphonates; Patient Compliance; Public Health Administration; Retrospective Studies; Risk Factors; Sex Factors; Student Health Services; Tenofovir; Universities; Zidovudine

2007
In vitro selection and characterization of human immunodeficiency virus type 1 resistant to Zidovudine and tenofovir.
    Nucleosides, nucleotides & nucleic acids, 2007, Volume: 26, Issue:5

    Topics: Adenine; Amino Acid Sequence; Cell Line, Transformed; Drug Resistance, Viral; HIV Reverse Transcriptase; HIV-1; Humans; Molecular Sequence Data; Mutation; Organophosphonates; Reverse Transcriptase Inhibitors; Sequence Homology, Amino Acid; Tenofovir; Zidovudine

2007
HPV oral infection. Case report of an HIV-positive Nigerian sex worker.
    Le infezioni in medicina, 2007, Volume: 15, Issue:2

    Topics: Adenine; Adult; Alphapapillomavirus; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Deoxycytidine; Dideoxynucleosides; Emtricitabine; Female; HIV Infections; Humans; Italy; Lamivudine; Lopinavir; Mouth Mucosa; Nigeria; Organophosphonates; Papillomavirus Infections; Pyrimidinones; Ritonavir; Sex Work; Stomatitis; Tenofovir; Treatment Refusal; Zidovudine

2007
Antiretroviral drug exposure in the female genital tract: implications for oral pre- and post-exposure prophylaxis.
    AIDS (London, England), 2007, Sep-12, Volume: 21, Issue:14

    Topics: Adenine; Administration, Oral; Adult; Alkynes; Anti-Retroviral Agents; Atazanavir Sulfate; Benzoxazines; Cyclopropanes; Deoxycytidine; Drug Therapy, Combination; Emtricitabine; Female; Genitalia, Female; HIV Infections; HIV Protease Inhibitors; Humans; Lamivudine; Lopinavir; Oligopeptides; Organophosphonates; Pyridines; Pyrimidinones; Reverse Transcriptase Inhibitors; Tenofovir; Zidovudine

2007
Variations in reverse transcriptase and RNase H domain mutations in human immunodeficiency virus type 1 clinical isolates are associated with divergent phenotypic resistance to zidovudine.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:11

    Topics: Adenine; Amino Acid Sequence; Deoxycytidine; Drug Resistance, Multiple, Viral; Genetic Variation; HIV Infections; HIV-1; Humans; Molecular Sequence Data; Mutation; Organophosphonates; Phenotype; Ribonuclease H; RNA-Directed DNA Polymerase; Sequence Homology, Amino Acid; Tenofovir; Zidovudine

2007
Novel drug resistance pattern associated with the mutations K70G and M184V in human immunodeficiency virus type 1 reverse transcriptase.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:12

    Topics: Adenine; Amino Acid Substitution; Deoxycytidine; Didanosine; Dideoxynucleosides; Drug Resistance, Multiple, Viral; Emtricitabine; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Molecular Sequence Data; Mutation; Organophosphonates; Reverse Transcriptase Inhibitors; Stavudine; Tenofovir; Zidovudine

2007
Adaptation of antiretroviral therapy in human immunodeficiency virus infection with central nervous system involvement.
    Journal of neurovirology, 2008, Volume: 14, Issue:1

    Topics: Adenine; Adult; AIDS Dementia Complex; Alkynes; Anti-HIV Agents; Anticonvulsants; Antiretroviral Therapy, Highly Active; Atazanavir Sulfate; Benzoxazines; Cerebrospinal Fluid; Cyclopropanes; Didanosine; HIV-1; Humans; Indinavir; Lamivudine; Male; Nelfinavir; Nevirapine; Oligopeptides; Organophosphonates; Pyridines; Ritonavir; Seizures; Stavudine; Tenofovir; Viral Load; Virus Replication; Zidovudine

2008
Cost-effectiveness analysis of emtricitabine/tenofovir versus lamivudine/zidovudine, in combination with efavirenz, in antiretroviral-naive, HIV-1-infected patients.
    Clinical therapeutics, 2008, Volume: 30, Issue:2

    Topics: Adenine; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Cost-Benefit Analysis; Cyclopropanes; Decision Trees; Deoxycytidine; Drug Costs; Emtricitabine; Health Care Costs; Health Resources; HIV Infections; HIV-1; Humans; Lamivudine; Models, Economic; Organophosphonates; Reverse Transcriptase Inhibitors; Tenofovir; Time Factors; Treatment Outcome; Zidovudine

2008
The human multidrug resistance protein 4 (MRP4, ABCC4): functional analysis of a highly polymorphic gene.
    The Journal of pharmacology and experimental therapeutics, 2008, Volume: 325, Issue:3

    Topics: Adenine; Antiviral Agents; Base Sequence; California; Cell Line; Ethnicity; Haplotypes; Humans; Molecular Sequence Data; Multidrug Resistance-Associated Proteins; Organophosphonates; Polymorphism, Single Nucleotide; Sequence Alignment; Sequence Analysis, DNA; White People; Zidovudine

2008
Targeting only reverse transcriptase with zidovudine/lamivudine/abacavir plus tenofovir in HIV-1-infected patients with multidrug-resistant virus: a multicentre pilot study.
    HIV medicine, 2008, Volume: 9, Issue:7

    Topics: Adenine; Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Dideoxynucleosides; Drug Resistance, Multiple, Viral; Female; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Male; Middle Aged; Organophosphonates; Pilot Projects; Reverse Transcriptase Inhibitors; RNA, Viral; Tenofovir; Thymidine; Viral Load; Zidovudine

2008
Weight evolution in HIV-1 infected women in Rwanda after stavudine substitution due to lipoatrophy: comparison of zidovudine with tenofovir/abacavir.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 2009, Volume: 103, Issue:6

    Topics: Adenine; Adult; Anti-HIV Agents; Body Weight; Dideoxynucleosides; Drug Therapy, Combination; Female; HIV-1; HIV-Associated Lipodystrophy Syndrome; Humans; Organophosphonates; Rwanda; Stavudine; Tenofovir; Treatment Outcome; Weight Loss; Zidovudine

2009
Gene induction for the treatment of methylmalonic aciduria.
    The journal of gene medicine, 2009, Volume: 11, Issue:4

    Topics: Adenine; Cisplatin; Drug Evaluation, Preclinical; Gene Expression Regulation; Green Fluorescent Proteins; HeLa Cells; Humans; Metabolism, Inborn Errors; Methylmalonyl-CoA Mutase; Organophosphonates; RNA, Messenger; Zidovudine

2009
Stop codon read-through of a methylmalonic aciduria mutation.
    Molecular genetics and metabolism, 2009, Volume: 97, Issue:4

    Topics: Adenine; Chromosomes, Artificial, Bacterial; Cisplatin; Codon, Terminator; Genes, Reporter; Gentamicins; HeLa Cells; Humans; Metabolism, Inborn Errors; Methylmalonyl-CoA Mutase; Mutation, Missense; Organophosphonates; RNA, Messenger; Zidovudine

2009
Quadruple nucleos(t)ide reverse transcriptase inhibitors-only regimen of tenofovir plus zidovudine/lamivudine/abacavir in heavily pre-treated HIV-1 infected patients: salvage therapy or backbone only?
    Current HIV research, 2009, Volume: 7, Issue:3

    Topics: Adenine; Amino Acid Substitution; Anti-HIV Agents; CD4 Lymphocyte Count; Dideoxynucleosides; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Mutation, Missense; Organophosphonates; Retrospective Studies; Salvage Therapy; Tenofovir; Treatment Outcome; Viral Load; Zidovudine

2009
The absence of HIV mutations in cerebrospinal fluid and in peripheral blood mononuclear cells during a regimen containing Trizivir plus tenofovir.
    Journal of chemotherapy (Florence, Italy), 2009, Volume: 21, Issue:4

    Topics: Adenine; Anti-HIV Agents; Cohort Studies; Drug Combinations; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Lamivudine; Leukocytes, Mononuclear; Mutation; Organophosphonates; Prospective Studies; Tenofovir; Viremia; Zidovudine

2009
Low-abundance HIV species and their impact on mutational profiles in patients with virological failure on once-daily abacavir/lamivudine/zidovudine and tenofovir.
    The Journal of antimicrobial chemotherapy, 2010, Volume: 65, Issue:2

    Topics: Adenine; Adolescent; Adult; Aged; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Dideoxynucleosides; Drug Combinations; Drug Resistance, Viral; HIV Infections; HIV-1; Humans; Lamivudine; Microbial Sensitivity Tests; Middle Aged; Mutation, Missense; Organophosphonates; RNA, Viral; Tenofovir; Treatment Failure; Viremia; Young Adult; Zidovudine

2010
Cost-effectiveness of tenofovir as first-line antiretroviral therapy in India.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2010, Feb-01, Volume: 50, Issue:3

    Topics: Adenine; Adult; Antifungal Agents; Antiretroviral Therapy, Highly Active; Cost-Benefit Analysis; Female; HIV Infections; Humans; India; Male; Organophosphonates; Stavudine; Survival Analysis; Tenofovir; Treatment Outcome; Zidovudine

2010
Treatment modification in human immunodeficiency virus-infected individuals starting combination antiretroviral therapy between 2005 and 2008.
    Archives of internal medicine, 2010, Jan-11, Volume: 170, Issue:1

    Topics: Adenine; Adult; AIDS-Related Opportunistic Infections; Alkynes; Anti-HIV Agents; Atazanavir Sulfate; Benzoxazines; Cyclopropanes; Deoxycytidine; Dideoxynucleosides; Drug Therapy, Combination; Emtricitabine; Female; HIV Infections; Humans; Lamivudine; Lopinavir; Male; Middle Aged; Nevirapine; Oligopeptides; Organophosphonates; Proportional Hazards Models; Prospective Studies; Pyridines; Pyrimidinones; Risk Factors; Switzerland; Tenofovir; Zidovudine

2010
International cohort analysis of the antiviral activities of zidovudine and tenofovir in the presence of the K65R mutation in reverse transcriptase.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:4

    Topics: Adenine; Amino Acid Substitution; Anti-HIV Agents; California; Cohort Studies; Drug Resistance, Viral; France; Genes, Viral; Genotype; HIV Infections; HIV Reverse Transcriptase; HIV-1; Multivariate Analysis; Mutation, Missense; Organophosphonates; RNA, Viral; Tenofovir; Zidovudine

2010
Inhibition of xenotropic murine leukemia virus-related virus by APOBEC3 proteins and antiviral drugs.
    Journal of virology, 2010, Volume: 84, Issue:11

    Topics: Adenine; Animals; Antiviral Agents; Cell Line, Tumor; Cytidine Deaminase; Gammaretrovirus; Humans; Leukemia Virus, Murine; Male; Mice; Mutation; Organophosphonates; Prostatic Neoplasms; Pyrrolidinones; Raltegravir Potassium; Retroviridae Infections; Tenofovir; Tumor Virus Infections; Zidovudine

2010
Second-line treatment in the Malawi antiretroviral programme: high early mortality, but good outcomes in survivors, despite extensive drug resistance at baseline.
    HIV medicine, 2010, Volume: 11, Issue:8

    Topics: Adenine; Adolescent; Adult; Anti-Retroviral Agents; Body Mass Index; CD4 Lymphocyte Count; Developing Countries; Drug Resistance, Viral; Drug Therapy, Combination; Drug-Related Side Effects and Adverse Reactions; Female; Genotype; HIV Infections; HIV-1; Humans; Malawi; Male; Medication Adherence; Middle Aged; National Health Programs; Organophosphonates; Prospective Studies; RNA, Viral; Statistics as Topic; Tenofovir; Treatment Failure; Tuberculosis; Urban Population; Viral Load; Zidovudine

2010
Positive and negative drug selection pressures on the N348I connection domain mutation: new insights from in vivo data.
    Antiviral therapy, 2010, Volume: 15, Issue:2

    Topics: Adenine; Alkynes; Anti-HIV Agents; Benzoxazines; Case-Control Studies; Cyclopropanes; Databases, Genetic; Drug Administration Schedule; Drug Resistance, Viral; Drug Therapy, Combination; HIV Reverse Transcriptase; HIV-1; Humans; Logistic Models; Mutation; Nevirapine; Organophosphonates; Reverse Transcriptase Inhibitors; Stavudine; Tenofovir; Zidovudine

2010
Evolution of drug resistance during 48 weeks of zidovudine/lamivudine/tenofovir in the absence of real-time viral load monitoring.
    Journal of acquired immune deficiency syndromes (1999), 2010, Volume: 55, Issue:2

    Topics: Adenine; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Drug Resistance, Viral; Genotype; HIV-1; Humans; Lamivudine; Mutation; Organophosphonates; Tenofovir; Time Factors; Viral Load; Zidovudine

2010
[Human immunodeficiency virus and Chagas disease coinfection treated successfully with benznidazole and a raltegravir-based antiretroviral regimen: a case report].
    Medicina clinica, 2011, Sep-10, Volume: 137, Issue:6

    Topics: Adenine; Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Atazanavir Sulfate; Chagas Disease; Drug Interactions; Drug Therapy, Combination; Female; HIV Infections; Humans; Lamivudine; Nitroimidazoles; Oligopeptides; Organophosphonates; Paraguay; Pyridines; Pyrrolidinones; Raltegravir Potassium; Ritonavir; Spain; Tenofovir; Trypanocidal Agents; Zidovudine

2011
Identification and characterization of persistent intracellular human immunodeficiency virus type 1 integrase strand transfer inhibitor activity.
    Antimicrobial agents and chemotherapy, 2011, Volume: 55, Issue:1

    Topics: Adenine; Anti-HIV Agents; Cell Line; HeLa Cells; HIV-1; Humans; Integrase Inhibitors; Organophosphonates; Pyrrolidinones; Quinolones; Raltegravir Potassium; Tenofovir; Zidovudine

2011
Pre-steady-state kinetic analysis of the incorporation of anti-HIV nucleotide analogs catalyzed by human X- and Y-family DNA polymerases.
    Antimicrobial agents and chemotherapy, 2011, Volume: 55, Issue:1

    Topics: Adenine; Anti-HIV Agents; DNA-Directed DNA Polymerase; Humans; Lamivudine; Molecular Structure; Organophosphonates; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Tenofovir; Zidovudine

2011
HIV-2 goes global: an unaddressed issue in Indian anti-retroviral programmes.
    The Indian journal of medical research, 2010, Volume: 132

    Topics: Adenine; Anti-HIV Agents; HIV Infections; HIV-2; Humans; India; Organophosphonates; Prevalence; Tenofovir; Zidovudine

2010
Tenofovir selectively regulates production of inflammatory cytokines and shifts the IL-12/IL-10 balance in human primary cells.
    Journal of acquired immune deficiency syndromes (1999), 2011, Aug-01, Volume: 57, Issue:4

    Topics: Adenine; Anti-HIV Agents; Cell Line; Chemokine CCL3; Gene Expression Regulation; Humans; Interleukin-10; Interleukin-12; Interleukin-8; Leukocytes, Mononuclear; Mitogen-Activated Protein Kinases; Monocytes; NF-kappa B; Organophosphonates; Tenofovir; Toll-Like Receptors; Tumor Necrosis Factor-alpha; Zidovudine

2011
Determination of nucleoside analog mono-, di-, and tri-phosphates in cellular matrix by solid phase extraction and ultra-sensitive LC-MS/MS detection.
    Journal of pharmaceutical and biomedical analysis, 2011, Sep-10, Volume: 56, Issue:2

    Topics: Adenine; Anion Exchange Resins; Antiviral Agents; Calibration; Chromatography, Liquid; Deoxycytidine; Diphosphates; Emtricitabine; Humans; Lamivudine; Leukocytes, Mononuclear; Nucleosides; Organophosphonates; Phosphates; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Solid Phase Extraction; Tandem Mass Spectrometry; Tenofovir; Zidovudine

2011
Cost and cost-effectiveness of switching from d4T or AZT to a TDF-based first-line regimen in a resource-limited setting in rural Lesotho.
    Journal of acquired immune deficiency syndromes (1999), 2011, Nov-01, Volume: 58, Issue:3

    Topics: Adenine; Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Cost-Benefit Analysis; Developing Countries; Female; Health Care Costs; HIV Infections; Humans; Lesotho; Male; Middle Aged; Organophosphonates; Pregnancy; Rural Population; Stavudine; Tenofovir; Zidovudine

2011
Comparative outcomes of tenofovir-based and zidovudine-based antiretroviral therapy regimens in Lusaka, Zambia.
    Journal of acquired immune deficiency syndromes (1999), 2011, Dec-15, Volume: 58, Issue:5

    Topics: Adenine; Adult; Anti-HIV Agents; Drug Therapy, Combination; Female; HIV Infections; Humans; Male; Organophosphonates; Proportional Hazards Models; Retrospective Studies; Risk Factors; Tenofovir; Zambia; Zidovudine

2011
Biochemical, inhibition and inhibitor resistance studies of xenotropic murine leukemia virus-related virus reverse transcriptase.
    Nucleic acids research, 2012, Volume: 40, Issue:1

    Topics: Adenine; Amino Acid Sequence; Aptamers, Nucleotide; beta-Galactosidase; DNA; HIV Reverse Transcriptase; Kinetics; Models, Molecular; Molecular Sequence Data; Moloney murine leukemia virus; Mutation; Nucleotides; Organophosphonates; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Sequence Homology, Amino Acid; Tenofovir; Xenotropic murine leukemia virus-related virus; Zidovudine

2012
Standardized comparison of the relative impacts of HIV-1 reverse transcriptase (RT) mutations on nucleoside RT inhibitor susceptibility.
    Antimicrobial agents and chemotherapy, 2012, Volume: 56, Issue:5

    Topics: Adenine; Algorithms; Anti-HIV Agents; Dideoxynucleosides; Drug Resistance, Multiple, Viral; Genomics; Genotype; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Least-Squares Analysis; Mutation; Nucleosides; Organophosphonates; Phenotype; Reverse Transcriptase Inhibitors; Tenofovir; Thymidine; Zidovudine

2012
Adverse drug reactions to antiretroviral therapy (ARVs): incidence, type and risk factors in Nigeria.
    BMC clinical pharmacology, 2012, Feb-27, Volume: 12

    Topics: Adenine; Adolescent; Adult; Alkynes; Anti-Retroviral Agents; Benzoxazines; Cohort Studies; Cyclopropanes; Drug-Related Side Effects and Adverse Reactions; Exanthema; Female; HIV Infections; Humans; Incidence; Lamivudine; Male; Middle Aged; Nevirapine; Nigeria; Organophosphonates; Pain; Retrospective Studies; Risk Factors; Stavudine; Tenofovir; Zidovudine

2012
Response of simian immunodeficiency virus to the novel nucleoside reverse transcriptase inhibitor 4'-ethynyl-2-fluoro-2'-deoxyadenosine in vitro and in vivo.
    Antimicrobial agents and chemotherapy, 2012, Volume: 56, Issue:9

    Topics: Adenine; Animals; Antiviral Agents; Cells, Cultured; Deoxyadenosines; Deoxycytidine; Emtricitabine; Leukocytes, Mononuclear; Macaca mulatta; Male; Mutation; Organophosphonates; Recurrence; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Simian Acquired Immunodeficiency Syndrome; Simian Immunodeficiency Virus; Tenofovir; Viral Load; Zidovudine

2012
Trends in HIV-1 reverse transcriptase resistance-associated mutations and antiretroviral prescription data from 2003-2010.
    Antiviral therapy, 2012, Volume: 17, Issue:6

    Topics: Adenine; Anti-HIV Agents; Deoxycytidine; Drug Prescriptions; Drug Resistance, Viral; Drug Therapy, Combination; Emtricitabine; Genotype; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Mutation; Organophosphonates; Prevalence; Reverse Transcriptase Inhibitors; Tenofovir; Treatment Failure; Zidovudine

2012
Monitoring of HAART regime antiretrovirals in serum of acquired immunodeficiency syndrome patients by micellar liquid chromatography.
    The Analyst, 2012, Sep-21, Volume: 137, Issue:18

    Topics: Acquired Immunodeficiency Syndrome; Adenine; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Chromatography, Liquid; Cyclopropanes; Drug Monitoring; Humans; Lamivudine; Organophosphonates; Stavudine; Tenofovir; Zidovudine

2012
Cost-effectiveness of tenofovir instead of zidovudine for use in first-line antiretroviral therapy in settings without virological monitoring.
    PloS one, 2012, Volume: 7, Issue:8

    Topics: Adenine; Adult; Africa South of the Sahara; Anti-Retroviral Agents; Cost-Benefit Analysis; Drug Resistance, Viral; Epidemics; Female; Genotype; HIV Infections; HIV-1; Humans; Male; Middle Aged; Organophosphonates; Stochastic Processes; Tenofovir; Treatment Outcome; Zidovudine

2012
Tenofovir-based regimens associated with less drug resistance in HIV-1-infected Nigerians failing first-line antiretroviral therapy.
    AIDS (London, England), 2013, Feb-20, Volume: 27, Issue:4

    Topics: Adenine; Adult; Cross-Sectional Studies; Drug Administration Schedule; Drug Resistance, Viral; Female; Genotype; HIV Seropositivity; HIV-1; Humans; Male; Mutation, Missense; Nigeria; Organophosphonates; Retrospective Studies; Reverse Transcriptase Inhibitors; RNA, Viral; Tenofovir; Treatment Failure; Viral Load; Zidovudine

2013
In vitro and ex vivo inhibition of human telomerase by anti-HIV nucleoside reverse transcriptase inhibitors (NRTIs) but not by non-NRTIs.
    PloS one, 2012, Volume: 7, Issue:11

    Topics: Adenine; Alkynes; Anti-HIV Agents; Benzoxazines; Cell Line; Cyclopropanes; Didanosine; Dideoxynucleosides; DNA Primers; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Nevirapine; Organophosphonates; Reverse Transcriptase Inhibitors; Stavudine; Telomerase; Tenofovir; Zidovudine

2012
[Assessment of mitochondrial toxicity induced by zidovudine and adefovir dipivoxil in rats].
    Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology, 2012, Volume: 20, Issue:10

    Topics: Adenine; Animals; DNA, Mitochondrial; Electron Transport Complex IV; Female; Kidney; Liver; Mitochondria; Mitochondria, Heart; Mitochondria, Liver; Mitochondria, Muscle; Muscle, Skeletal; Myocardium; Organophosphonates; Rats; Rats, Sprague-Dawley; Zidovudine

2012
Inhibition of telomerase activity by human immunodeficiency virus (HIV) nucleos(t)ide reverse transcriptase inhibitors: a potential factor contributing to HIV-associated accelerated aging.
    The Journal of infectious diseases, 2013, Volume: 207, Issue:7

    Topics: Adenine; Adult; Aging; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Case-Control Studies; Cells, Cultured; Deoxycytidine; Dideoxynucleosides; Emtricitabine; Enzyme Activation; Female; HIV; HIV Infections; Humans; Lamivudine; Leukocytes, Mononuclear; Male; Middle Aged; Organophosphonates; Polymerase Chain Reaction; Regression Analysis; Reverse Transcriptase Inhibitors; Risk Factors; Telomerase; Telomere; Telomere Shortening; Tenofovir; Time Factors; Young Adult; Zidovudine

2013
Comprehensive in vitro analysis of simian retrovirus type 4 susceptibility to antiretroviral agents.
    Journal of virology, 2013, Volume: 87, Issue:8

    Topics: Adenine; Amino Acid Sequence; Animals; Anti-Retroviral Agents; Genes, Reporter; Integrases; Luciferases; Microbial Sensitivity Tests; Organophosphonates; Protease Inhibitors; Retroviruses, Simian; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Sequence Alignment; Tenofovir; Zidovudine

2013
Cardiometabolic risk factors among HIV patients on antiretroviral therapy.
    Lipids in health and disease, 2013, Apr-10, Volume: 12

    Topics: Adenine; Adolescent; Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Cardiovascular Diseases; Cholesterol, HDL; Cholesterol, LDL; Cyclopropanes; Female; HIV; HIV Infections; Humans; Insulin Resistance; Lamivudine; Male; Middle Aged; Nevirapine; Organophosphonates; Risk Factors; Stavudine; Tenofovir; Triglycerides; Zambia; Zidovudine

2013
Harnessing autophagy for cell fate control gene therapy.
    Autophagy, 2013, Volume: 9, Issue:7

    Topics: Adenine; Animals; Antigens, CD19; Apoptosis; Autophagy; CD4-Positive T-Lymphocytes; Cell Lineage; Cell Proliferation; Cell Survival; Genetic Therapy; Humans; Lentivirus; Mice; Nucleoside-Phosphate Kinase; Phenotype; Sirolimus; Transduction, Genetic; Transgenes; Zidovudine

2013
Left ventricular hypertrophy detected by echocardiography in HIV-infected patients.
    European journal of internal medicine, 2013, Volume: 24, Issue:6

    Topics: Adenine; Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Carbamates; Comorbidity; Cross-Sectional Studies; Cyclopropanes; Diabetes Mellitus; Drug Combinations; Dyslipidemias; Echocardiography; Female; Furans; HIV Infections; Humans; Hypertension; Hypertrophy, Left Ventricular; Lamivudine; Lopinavir; Male; Middle Aged; Nevirapine; Organophosphates; Organophosphonates; Risk Factors; Ritonavir; Smoking; Spain; Sulfonamides; Tenofovir; Zidovudine

2013
Drug-resistance development differs between HIV-1-infected patients failing first-line antiretroviral therapy containing nonnucleoside reverse transcriptase inhibitors with and without thymidine analogues.
    HIV medicine, 2013, Volume: 14, Issue:9

    Topics: Adenine; Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Deoxycytidine; Dideoxynucleosides; Drug Combinations; Drug Resistance, Viral; Emtricitabine; Female; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Male; Middle Aged; Organophosphonates; Tenofovir; Thymidine; Treatment Failure; Viral Load; Zidovudine

2013
Nucleoside reverse transcriptase inhibitor resistance mutations associated with first-line stavudine-containing antiretroviral therapy: programmatic implications for countries phasing out stavudine.
    The Journal of infectious diseases, 2013, Jun-15, Volume: 207 Suppl 2

    Topics: Adenine; Alkynes; Anti-Retroviral Agents; Benzoxazines; Cyclopropanes; Databases, Factual; Drug Resistance, Viral; Drug Therapy, Combination; Genotype; HIV Infections; HIV-1; Humans; Mutation, Missense; Nevirapine; Organophosphonates; Reverse Transcriptase Inhibitors; RNA, Viral; Stavudine; Tenofovir; Zidovudine

2013
Comparison of tenofovir, zidovudine, or stavudine as part of first-line antiretroviral therapy in a resource-limited-setting: a cohort study.
    PloS one, 2013, Volume: 8, Issue:5

    Topics: Adenine; Adolescent; Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Cohort Studies; Female; Health Resources; HIV; HIV Infections; Humans; Male; Middle Aged; Organophosphonates; Residence Characteristics; RNA, Viral; Stavudine; Tenofovir; Young Adult; Zidovudine

2013
Tenofovir disoproxil fumarate-associated nephrotoxicity in HIV-infected patients: a prospective controlled study.
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2013, Volume: 96, Issue:4

    Topics: Adenine; Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Female; HIV Infections; Humans; Incidence; Kidney Diseases; Male; Organophosphonates; Prospective Studies; Tenofovir; Zidovudine

2013
[Ophthalmological alterations at the initial diagnosis of HIV infection].
    Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft, 2014, Volume: 111, Issue:7

    Topics: Adenine; Adult; Antiretroviral Therapy, Highly Active; Cyclohexanes; Deoxycytidine; Drug Therapy, Combination; Early Diagnosis; Emtricitabine; Eye Infections, Viral; HIV Infections; Humans; Lopinavir; Male; Maraviroc; Organophosphonates; Retinal Diseases; Syndrome; Tenofovir; Treatment Outcome; Triazoles; Zidovudine

2014
Comparison of cardiovascular disease risk markers in HIV-infected patients receiving abacavir and tenofovir: the nucleoside inflammation, coagulation and endothelial function (NICE) study.
    Antiviral therapy, 2014, Volume: 19, Issue:2

    Topics: Adenine; Adult; Anti-HIV Agents; Biomarkers; Blood Coagulation; Cardiovascular Diseases; Dideoxynucleosides; Endothelium, Vascular; Female; HIV Infections; Humans; Inflammation; Male; Middle Aged; Organophosphonates; Risk Factors; Tenofovir; Zidovudine

2014
Tenofovir or zidovudine in second-line antiretroviral therapy after stavudine failure in southern Africa.
    Antiviral therapy, 2014, Volume: 19, Issue:5

    Topics: Adenine; Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Female; HIV Infections; Humans; Male; Middle Aged; Organophosphonates; Retreatment; South Africa; Stavudine; Tenofovir; Treatment Failure; Treatment Outcome; Viral Load; Zidovudine

2014
Molecular basis of the association of H208Y and thymidine analogue resistance mutations M41L, L210W and T215Y in the HIV-1 reverse transcriptase of treated patients.
    Antiviral research, 2014, Volume: 106

    Topics: Adenine; Anti-HIV Agents; Cell Line; Drug Resistance, Viral; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Microbial Sensitivity Tests; Mutation, Missense; Organophosphonates; Reverse Transcription; Tenofovir; Zidovudine

2014
SAMHD1 has differential impact on the efficacies of HIV nucleoside reverse transcriptase inhibitors.
    Antimicrobial agents and chemotherapy, 2014, Volume: 58, Issue:8

    Topics: Adenine; Cell Line; Dideoxynucleotides; Gene Expression; Genes, Reporter; HIV Reverse Transcriptase; HIV-1; Host-Pathogen Interactions; Humans; Lamivudine; Luciferases; Monocytes; Monomeric GTP-Binding Proteins; Organophosphonates; Reverse Transcriptase Inhibitors; RNA, Small Interfering; SAM Domain and HD Domain-Containing Protein 1; Stavudine; Tenofovir; Virus Replication; Zidovudine

2014
[To evaluate the changes in body composition in male human immunodeficiency virus-related lipodystrophy after different treatment regimens by dual-energy X-ray absorptiometry].
    Zhonghua nei ke za zhi, 2014, Volume: 53, Issue:8

    Topics: Absorptiometry, Photon; Adenine; Anti-HIV Agents; Antiviral Agents; Body Composition; HIV Infections; HIV-Associated Lipodystrophy Syndrome; Humans; Male; Organophosphonates; Stavudine; Tenofovir; Zidovudine

2014
Commentary: The place of tenofovir disoproxil fumarate in pediatric antiretroviral therapy.
    The Pediatric infectious disease journal, 2015, Volume: 34, Issue:4

    Topics: Adenine; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Drug Utilization; Drug-Related Side Effects and Adverse Reactions; Female; HIV Infections; HIV-1; Humans; Male; Organophosphonates; Stavudine; Zidovudine

2015
Is zidovudine first-line therapy virologically comparable to tenofovir in resource-limited settings?
    Tropical medicine & international health : TM & IH, 2015, Volume: 20, Issue:7

    Topics: Adenine; Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Cross-Sectional Studies; Cyclopropanes; Female; Health Resources; HIV; HIV Infections; Humans; Lamivudine; Lesotho; Logistic Models; Male; Middle Aged; Organophosphonates; Tenofovir; Viral Load; Zidovudine

2015
Nationwide Study of Drug Resistance Mutations in HIV-1 Infected Individuals under Antiretroviral Therapy in Brazil.
    International journal of molecular sciences, 2021, May-18, Volume: 22, Issue:10

    Topics: Adenine; Adult; Aged; Anti-HIV Agents; Brazil; Drug Resistance, Viral; Female; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Male; Middle Aged; Mutation; Reverse Transcriptase Inhibitors; Tenofovir; Treatment Failure; Viral Load; Zidovudine

2021