Compounds > zeneca zd 6169
Page last updated: 2024-09-05

zeneca zd 6169 and n-cyano-n'-(1,1-dimethylpropyl)-n''-(3-pyridinyl)guanidine

zeneca zd 6169 has been researched along with n-cyano-n'-(1,1-dimethylpropyl)-n''-(3-pyridinyl)guanidine in 5 studies

Compound Research Comparison

Studies
(zeneca zd 6169)		Trials
(zeneca zd 6169)		Recent Studies (post-2010)
(zeneca zd 6169)		Studies
(n-cyano-n'-(1,1-dimethylpropyl)-n''-(3-pyridinyl)guanidine)		Trials
(n-cyano-n'-(1,1-dimethylpropyl)-n''-(3-pyridinyl)guanidine)		Recent Studies (post-2010) (n-cyano-n'-(1,1-dimethylpropyl)-n''-(3-pyridinyl)guanidine)
42038708

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (20.00)18.2507
2000's4 (80.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Altenbach, RJ; Bai, H; Brioni, JD; Brune, ME; Buckner, SA; Carroll, WA; Cassidy, C; Chen, Y; Coghlan, MJ; Daza, AV; Drizin, I; Fey, TA; Fitzgerald, M; Gopalakrishnan, M; Gregg, RJ; Henry, RF; Holladay, MW; King, LL; Kort, ME; Kym, PR; Milicic, I; Sullivan, JP; Tang, R; Turner, SC; Whiteaker, KL; Yi, L; Zhang, H1
Altenbach, RJ; Brune, ME; Buckner, SA; Carroll, WA; Coghlan, MJ; Daza, AV; Fabiyi, A; Gopalakrishnan, M; Henry, RF; Khilevich, A; Kort, ME; Milicic, I; Scott, VE; Smith, JC; Whiteaker, KL1
Brown, FJ; Empfield, J; Li, JH; McConville, M; Ohnmacht, CJ; Potter-Lee, L; Russell, K; Stetz, SL; Trainor, DA; Trivedi, S1
Brioni, JD; Buckner, SA; Coghlan, MJ; Feng, J; Gopalakrishnan, M; Shieh, CC; Sullivan, JP1
Brune, ME; Buckner, SA; Coghlan, M; Daza, A; Fey, TA; Gopalakrishnan, M; Milicic, I1

Other Studies

5 other study(ies) available for zeneca zd 6169 and n-cyano-n'-(1,1-dimethylpropyl)-n''-(3-pyridinyl)guanidine

ArticleYear
Synthesis and structure-activity relationships of a novel series of 2,3,5,6,7,9-hexahydrothieno[3,2-b]quinolin-8(4H)-one 1,1-dioxide K(ATP) channel openers: discovery of (-)-(9S)-9-(3-bromo-4-fluorophenyl)-2,3,5,6,7,9- hexahydrothieno[3,2-b]quinolin-8(4H)
    Journal of medicinal chemistry, 2004, Jun-03, Volume: 47, Issue:12

    Topics: Adenosine Triphosphate; Animals; Cyclic S-Oxides; Electric Stimulation; Guinea Pigs; Hemodynamics; In Vitro Techniques; Membrane Potentials; Muscle Contraction; Muscle, Smooth; Potassium Channels; Quinolones; Stereoisomerism; Structure-Activity Relationship; Swine; Urinary Bladder; Urodynamics

2004
Effects of substitution on 9-(3-bromo-4-fluorophenyl)-5,9-dihydro-3H,4H-2,6-dioxa-4- azacyclopenta[b]naphthalene-1,8-dione, a dihydropyridine ATP-sensitive potassium channel opener.
    Journal of medicinal chemistry, 2006, Nov-16, Volume: 49, Issue:23

    Topics: Adenosine Triphosphate; Animals; Aza Compounds; Cell Line; Crystallography, X-Ray; Dihydropyridines; Electric Stimulation; Heterocyclic Compounds, 3-Ring; In Vitro Techniques; Ion Channel Gating; Mice; Muscle Contraction; Muscle, Smooth; Naphthalenes; Potassium Channels, Inwardly Rectifying; Stereoisomerism; Structure-Activity Relationship; Swine; Urinary Bladder

2006
K-channel opening activity of ZD6169 and its analogs: effect on 86Rb efflux and 3H-P1075 binding in bladder smooth muscle.
    Pharmacology, 1995, Volume: 50, Issue:6

    Topics: Amides; Animals; Benzophenones; Benzopyrans; Cromakalim; Dose-Response Relationship, Drug; Guanidines; Guinea Pigs; Kinetics; Muscle, Smooth; Potassium Channels; Pyridines; Pyrroles; Rubidium; Urinary Bladder; Vasodilator Agents

1995
Functional implication of spare ATP-sensitive K(+) channels in bladder smooth muscle cells.
    The Journal of pharmacology and experimental therapeutics, 2001, Volume: 296, Issue:3

    Topics: Acetylcholine; Amides; Animals; Benzophenones; Drug Interactions; Electrophysiology; Guanidines; Guinea Pigs; In Vitro Techniques; Membrane Potentials; Membrane Proteins; Muscle Relaxation; Muscle, Smooth; Pinacidil; Potassium Channels; Pyridines; Swine; Urinary Bladder; Vasodilator Agents

2001
Pharmacological characterization of urinary bladder smooth muscle contractility following partial bladder outlet obstruction in pigs.
    European journal of pharmacology, 2006, Feb-17, Volume: 532, Issue:1-2

    Topics: Adenosine Triphosphate; Amides; Animals; Benzophenones; Carbachol; Cholinergic Agonists; Cromakalim; Cyclic S-Oxides; Diazoxide; Dose-Response Relationship, Drug; Electric Stimulation; Female; Guanidines; Histamine; Hypertrophy; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Potassium Channels; Potassium Chloride; Pyridines; Quinolones; Serotonin; Serotonin Agents; Swine; Urinary Bladder; Urinary Bladder Neck Obstruction; Vasodilator Agents

2006