Compounds > zeneca zd 6169
Page last updated: 2024-09-05

zeneca zd 6169 and capsaicin

zeneca zd 6169 has been researched along with capsaicin in 4 studies

Compound Research Comparison

Studies
(zeneca zd 6169)		Trials
(zeneca zd 6169)		Recent Studies (post-2010)
(zeneca zd 6169)		Studies
(capsaicin)		Trials
(capsaicin)		Recent Studies (post-2010) (capsaicin)
420311,2386613,410

Protein Interaction Comparison

ProteinTaxonomyzeneca zd 6169 (IC50)capsaicin (IC50)
Transient receptor potential cation channel subfamily V member 1Rattus norvegicus (Norway rat)0.019
Lysine-specific histone demethylase 1AHomo sapiens (human)0.6
Bile salt export pumpHomo sapiens (human)10
Cytochrome P450 1A2Homo sapiens (human)3
Prostaglandin G/H synthase 1Homo sapiens (human)2.6755
Transient receptor potential cation channel subfamily V member 1Homo sapiens (human)0.008

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (50.00)18.2507
2000's1 (25.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
de Groat, WC; Yu, Y2
de Groat, WC; Fraser, MO; Yu, Y1

Other Studies

4 other study(ies) available for zeneca zd 6169 and capsaicin

ArticleYear
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Effects of ZD6169, a KATP channel opener, on bladder hyperactivity and spinal c-fos expression evoked by bladder irritation in rats.
    Brain research, 1998, Oct-05, Volume: 807, Issue:1-2

    Topics: Adenosine Triphosphate; Amides; Animals; Benzophenones; Capsaicin; Drug Evaluation, Preclinical; Female; Ion Channel Gating; Irritants; Nerve Tissue Proteins; Neurotoxins; Potassium Channels; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Spinal Cord; Urinary Bladder

1998
Effects of ZD6169, a K(ATP) channel opener, on the micturition reflex in the rat.
    The Journal of pharmacology and experimental therapeutics, 1999, Volume: 290, Issue:2

    Topics: Adenosine Triphosphate; Amides; Animals; Benzophenones; Capsaicin; Female; Glyburide; Hypoglycemic Agents; Mechanoreceptors; Muscle Contraction; Muscle, Smooth; Potassium Channels; Pressure; Rats; Rats, Wistar; Reflex; Urinary Bladder; Urination; Urodynamics

1999
Effects of ZD6169, a K ATP channel opener, on neurally-mediated plasma extravasation in the rat urinary bladder induced by chemical or electrical stimulation of nerves.
    Brain research, 2004, Jan-16, Volume: 996, Issue:1

    Topics: Acetic Acid; Amides; Analysis of Variance; Animals; Anti-Arrhythmia Agents; Benzophenones; Blood Proteins; Capsaicin; Drug Interactions; Electric Stimulation; Evans Blue; Extravasation of Diagnostic and Therapeutic Materials; Female; Glyburide; Membrane Proteins; Neurons, Afferent; Potassium Channels; Rats; Rats, Wistar; Stimulation, Chemical; Urethra; Urinary Bladder

2004