Page last updated: 2024-09-03

zd 7288 and prazosin

zd 7288 has been researched along with prazosin in 2 studies

Compound Research Comparison

Studies (zd 7288)	Trials (zd 7288)	Recent Studies (post-2010) (zd 7288)	Studies (prazosin)	Trials (prazosin)	Recent Studies (post-2010) (prazosin)
382	0	137	7,914	713	682

Protein Interaction Comparison

Protein	Taxonomy	prazosin (IC50)
Solute carrier family 22 member 1	Homo sapiens (human)	5.87
Interstitial collagenase	Homo sapiens (human)	4.036
Alpha-2A adrenergic receptor	Homo sapiens (human)	2.638
Matrix metalloproteinase-9	Homo sapiens (human)	6.963
Alpha-1B adrenergic receptor	Rattus norvegicus (Norway rat)	0.0008
Ribosyldihydronicotinamide dehydrogenase [quinone]	Homo sapiens (human)	0.0078
Alpha-2B adrenergic receptor	Homo sapiens (human)	0.29
Alpha-2C adrenergic receptor	Homo sapiens (human)	0.647
Alpha-1D adrenergic receptor	Rattus norvegicus (Norway rat)	0.0008
Alpha-1D adrenergic receptor	Homo sapiens (human)	0.0007
Bromodomain-containing protein 2	Homo sapiens (human)	0.0009
Alpha-1A adrenergic receptor	Homo sapiens (human)	0.0006
Alpha-1B adrenergic receptor	Homo sapiens (human)	0.0006
5-hydroxytryptamine receptor 2B	Homo sapiens (human)	4.118
Alpha-1A adrenergic receptor	Rattus norvegicus (Norway rat)	0.0008
5-hydroxytryptamine receptor 7	Cavia porcellus (domestic guinea pig)	9.9
Potassium voltage-gated channel subfamily H member 2	Homo sapiens (human)	1.5849
Multidrug and toxin extrusion protein 1	Homo sapiens (human)	1.6

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (50.00)	29.6817
2010's	1 (50.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Cox, CL; Govindaiah, G	1
Amodeo, FS; Brummett, CM; Hong, EK; Janda, AM; Lydic, R	1

Other Studies

2 other study(ies) available for zd 7288 and prazosin

Article	Year
Excitatory actions of dopamine via D1-like receptors in the rat lateral geniculate nucleus. Journal of neurophysiology, 2005, Volume: 94, Issue:6 Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Action Potentials; Adrenergic alpha-Antagonists; Analysis of Variance; Anesthetics, Local; Animals; Animals, Newborn; Benzazepines; Bromocriptine; Carbazoles; Colforsin; Cyclic AMP; Dopamine; Dopamine Agonists; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Enzyme Inhibitors; Geniculate Bodies; In Vitro Techniques; Indoles; Neurons; Patch-Clamp Techniques; Prazosin; Pyrimidines; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Tetrodotoxin; Thionucleotides	2005
Perineural dexmedetomidine added to ropivacaine for sciatic nerve block in rats prolongs the duration of analgesia by blocking the hyperpolarization-activated cation current. Anesthesiology, 2011, Volume: 115, Issue:4 Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Amides; Analgesia; Anesthetics, Local; Animals; Behavior, Animal; Colforsin; Cyclic Nucleotide-Gated Cation Channels; Dexmedetomidine; Dose-Response Relationship, Drug; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; Hypnotics and Sedatives; Idazoxan; Male; Nerve Block; Pain Measurement; Potassium Channel Blockers; Potassium Channels; Prazosin; Pyrimidines; Rats; Rats, Sprague-Dawley; Ropivacaine; Sciatic Nerve	2011

Article

Year

Excitatory actions of dopamine via D1-like receptors in the rat lateral geniculate nucleus.

Journal of neurophysiology, 2005, Volume: 94, Issue:6

Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Action Potentials; Adrenergic alpha-Antagonists; Analysis of Variance; Anesthetics, Local; Animals; Animals, Newborn; Benzazepines; Bromocriptine; Carbazoles; Colforsin; Cyclic AMP; Dopamine; Dopamine Agonists; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Enzyme Inhibitors; Geniculate Bodies; In Vitro Techniques; Indoles; Neurons; Patch-Clamp Techniques; Prazosin; Pyrimidines; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Tetrodotoxin; Thionucleotides

2005

Perineural dexmedetomidine added to ropivacaine for sciatic nerve block in rats prolongs the duration of analgesia by blocking the hyperpolarization-activated cation current.

Anesthesiology, 2011, Volume: 115, Issue:4

Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Amides; Analgesia; Anesthetics, Local; Animals; Behavior, Animal; Colforsin; Cyclic Nucleotide-Gated Cation Channels; Dexmedetomidine; Dose-Response Relationship, Drug; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; Hypnotics and Sedatives; Idazoxan; Male; Nerve Block; Pain Measurement; Potassium Channel Blockers; Potassium Channels; Prazosin; Pyrimidines; Rats; Rats, Sprague-Dawley; Ropivacaine; Sciatic Nerve

2011