Compounds > zd 7288
Page last updated: 2024-09-03

zd 7288 and nifedipine

zd 7288 has been researched along with nifedipine in 2 studies

Compound Research Comparison

Studies
(zd 7288)		Trials
(zd 7288)		Recent Studies (post-2010)
(zd 7288)		Studies
(nifedipine)		Trials
(nifedipine)		Recent Studies (post-2010) (nifedipine)
382013716,0242,4961,505

Protein Interaction Comparison

ProteinTaxonomyzd 7288 (IC50)nifedipine (IC50)
perilipin-5Homo sapiens (human)7.133
perilipin-1Homo sapiens (human)9.619
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform aHomo sapiens (human)8.376
Voltage-dependent L-type calcium channel subunit alpha-1CCavia porcellus (domestic guinea pig)0.0429
Voltage-dependent L-type calcium channel subunit alpha-1FHomo sapiens (human)0.035
Cytochrome P450 1A2Homo sapiens (human)0.3
Cytochrome P450 3A4Homo sapiens (human)10
Adenosine receptor A3Homo sapiens (human)7.214
Cytochrome P450 2C9 Homo sapiens (human)3.06
5-hydroxytryptamine receptor 2ARattus norvegicus (Norway rat)10
Alpha-1B adrenergic receptorRattus norvegicus (Norway rat)7.214
Voltage-dependent L-type calcium channel subunit alpha-1CRattus norvegicus (Norway rat)0.0385
Potassium voltage-gated channel subfamily A member 5Homo sapiens (human)6.1
3-oxo-5-alpha-steroid 4-dehydrogenase 1 Rattus norvegicus (Norway rat)1.12
Adenosine receptor A1Homo sapiens (human)7.701
3-oxo-5-alpha-steroid 4-dehydrogenase 2Rattus norvegicus (Norway rat)1.12
C-C chemokine receptor type 2Homo sapiens (human)2.191
Alpha-1A adrenergic receptorRattus norvegicus (Norway rat)7.214
Cytochrome P450 2J2Homo sapiens (human)3.06
Voltage-dependent L-type calcium channel subunit alpha-1D Homo sapiens (human)0.4733
Voltage-dependent L-type calcium channel subunit alpha-1CMus musculus (house mouse)1.2
Voltage-dependent L-type calcium channel subunit alpha-1SMus musculus (house mouse)1.2
Voltage-dependent L-type calcium channel subunit alpha-1SHomo sapiens (human)0.035
Voltage-dependent L-type calcium channel subunit alpha-1CHomo sapiens (human)0.0394
Myosin light chain kinase, smooth muscleHomo sapiens (human)2.02
Potassium channel subfamily K member 2 Bos taurus (cattle)8.2
Indoleamine 2,3-dioxygenase 2Mus musculus (house mouse)1.5
Voltage-dependent L-type calcium channel subunit alpha-1DMus musculus (house mouse)1.2
Voltage-dependent L-type calcium channel subunit alpha-1FMus musculus (house mouse)1.2

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (50.00)18.2507
2000's1 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Choate, JK; Paterson, DJ; Sears, CE1
Colino, A; Halliwell, JV; Sánchez-Alonso, JL1

Other Studies

2 other study(ies) available for zd 7288 and nifedipine

ArticleYear
Inhibition of nitric oxide synthase slows heart rate recovery from cholinergic activation.
    Journal of applied physiology (Bethesda, Md. : 1985), 1998, Volume: 84, Issue:5

    Topics: Acetylcholine; Adrenergic alpha-Agonists; Animals; Arginine; Calcium Channel Blockers; Cardiovascular Agents; Cesium; Electric Stimulation; Enzyme Inhibitors; Guinea Pigs; Heart Atria; Heart Rate; Male; Nifedipine; Nitric Oxide; Nitric Oxide Synthase; Norepinephrine; omega-N-Methylarginine; Pyrimidines; Vagus Nerve

1998
ZD 7288 inhibits T-type calcium current in rat hippocampal pyramidal cells.
    Neuroscience letters, 2008, Jul-18, Volume: 439, Issue:3

    Topics: Animals; Animals, Newborn; Calcium Channel Blockers; Calcium Channels, T-Type; Cardiovascular Agents; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Electric Stimulation; Hippocampus; In Vitro Techniques; Membrane Potentials; Nickel; Nifedipine; Patch-Clamp Techniques; Pyramidal Cells; Pyrimidines; Rats; Rats, Wistar; Sodium Channel Blockers; Tetrodotoxin

2008