Page last updated: 2024-09-03

zd 7288 and loperamide

zd 7288 has been researched along with loperamide in 2 studies

Compound Research Comparison

Studies
(zd 7288)
Trials
(zd 7288)
Recent Studies (post-2010)
(zd 7288)
Studies
(loperamide)
Trials
(loperamide)
Recent Studies (post-2010) (loperamide)
38201371,358196488

Protein Interaction Comparison

ProteinTaxonomyzd 7288 (IC50)loperamide (IC50)
Cocaine esteraseHomo sapiens (human)5.7
Beta-2 adrenergic receptorHomo sapiens (human)3.005
ATP-dependent translocase ABCB1Homo sapiens (human)2.5
Replicase polyprotein 1abSevere acute respiratory syndrome coronavirus 29.27
Cytochrome P450 2D6Homo sapiens (human)2
Histamine H2 receptorHomo sapiens (human)3.081
Sodium-dependent serotonin transporterHomo sapiens (human)2.202
Mu-type opioid receptorHomo sapiens (human)0.0014
D(3) dopamine receptorHomo sapiens (human)1.337
Delta-type opioid receptorHomo sapiens (human)0.896
Kappa-type opioid receptorHomo sapiens (human)3.125
5-hydroxytryptamine receptor 2BHomo sapiens (human)4.105
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)0.033
Sodium channel protein type 5 subunit alphaHomo sapiens (human)0.239
Sigma non-opioid intracellular receptor 1Homo sapiens (human)0.628

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bowlby, MR; Dunlop, J; Lee, YT; Mayer, S; Shan, QJ; Vasilyev, DV1
Araneda, RC; Greer, CA; Maurer, LR; Miller, AM; Mobley, AS; Müller, F1

Other Studies

2 other study(ies) available for zd 7288 and loperamide

ArticleYear
Novel pharmacological activity of loperamide and CP-339,818 on human HCN channels characterized with an automated electrophysiology assay.
    European journal of pharmacology, 2008, Feb-26, Volume: 581, Issue:1-2

    Topics: Aminoquinolines; Antidiarrheals; Benzazepines; Cell Line; Chlorides; Cyclic Nucleotide-Gated Cation Channels; Dose-Response Relationship, Drug; Humans; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; Imines; Loperamide; Muscle Proteins; Potassium Channels; Pyrimidines; Quinolines

2008
Hyperpolarization-activated cyclic nucleotide-gated channels in olfactory sensory neurons regulate axon extension and glomerular formation.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2010, Dec-08, Volume: 30, Issue:49

    Topics: Animals; Animals, Newborn; Antidiarrheals; Axons; Biophysics; Cardiotonic Agents; Cells, Cultured; Cyclic Nucleotide-Gated Cation Channels; Electric Stimulation; Embryo, Mammalian; GAP-43 Protein; Gene Expression Regulation, Developmental; Green Fluorescent Proteins; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; Ion Channels; Loperamide; Membrane Potentials; Mice; Mice, Inbred C57BL; Mice, Knockout; Neural Cell Adhesion Molecules; Neurogenesis; Olfactory Bulb; Patch-Clamp Techniques; Potassium Channels; Pyrimidines; Receptors, Odorant; Sensory Receptor Cells

2010