zd 7288 has been researched along with lamotrigine in 4 studies
| Studies (zd 7288) | Trials (zd 7288) | Recent Studies (post-2010) (zd 7288) | Studies (lamotrigine) | Trials (lamotrigine) | Recent Studies (post-2010) (lamotrigine) |
|---|---|---|---|---|---|
| 382 | 0 | 137 | 3,550 | 501 | 1,351 |
| Protein | Taxonomy | zd 7288 (IC50) | lamotrigine (IC50) |
|---|---|---|---|
| Sodium channel protein type 2 subunit alpha | Homo sapiens (human) | 10 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Deng, P; Fan, Y; Lu, HC; Schulz, PE; Wang, YC; Xu, ZC | 1 |
| Albertson, AJ; Hablitz, JJ; Yang, J | 1 |
| Migliore, M; Migliore, R | 1 |
| Elgersma, Y; Gutmann, DH; Hojjati, MR; Kushner, SA; Levelt, CN; Li, KW; Mientjes, E; Omrani, A; Silva, AJ; Smit, AB; van der Vaart, T; van Woerden, GM | 1 |
4 other study(ies) available for zd 7288 and lamotrigine
| Article | Year |
|---|---|
Transient cerebral ischemia increases CA1 pyramidal neuron excitability.
Topics: Animals; Cardiovascular Agents; Cell Death; Disease Models, Animal; Dose-Response Relationship, Radiation; Electric Stimulation; Excitatory Amino Acid Antagonists; Hippocampus; In Vitro Techniques; Ischemic Attack, Transient; Lamotrigine; Male; Membrane Potentials; Patch-Clamp Techniques; Pyramidal Cells; Pyrimidines; Rats; Statistics, Nonparametric; Triazines | 2008 |
Decreased hyperpolarization-activated currents in layer 5 pyramidal neurons enhances excitability in focal cortical dysplasia.
Topics: Action Potentials; Animals; Animals, Newborn; Anticonvulsants; Cerebral Cortex; Cyclic Nucleotide-Gated Cation Channels; Epilepsy; Excitatory Postsynaptic Potentials; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; Lamotrigine; Malformations of Cortical Development; Organ Culture Techniques; Patch-Clamp Techniques; Potassium Channels; Pyramidal Cells; Pyrimidines; Rats; Rats, Sprague-Dawley; Triazines; Voltage-Sensitive Dye Imaging | 2011 |
Know your current I(h): interaction with a shunting current explains the puzzling effects of its pharmacological or pathological modulations.
Topics: Action Potentials; Animals; CA1 Region, Hippocampal; Computer Simulation; Electrophysiological Phenomena; Epilepsy; Humans; In Vitro Techniques; Lamotrigine; Models, Neurological; Potassium Channels; Pyrimidines; Triazines | 2012 |
HCN channels are a novel therapeutic target for cognitive dysfunction in Neurofibromatosis type 1.
Topics: Animals; Cognition Disorders; Disease Models, Animal; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Hippocampus; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; Lamotrigine; Male; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Transgenic; Motor Activity; Mutation; Neural Inhibition; Neurofibromatosis 1; Neurofibromin 1; Neuronal Plasticity; Neurons; Potassium Channels; Pyrimidines; Signal Transduction; Triazines | 2015 |