zd 7288 has been researched along with guanfacine in 1 studies
| Studies (zd 7288) | Trials (zd 7288) | Recent Studies (post-2010) (zd 7288) | Studies (guanfacine) | Trials (guanfacine) | Recent Studies (post-2010) (guanfacine) |
|---|---|---|---|---|---|
| 382 | 0 | 137 | 784 | 180 | 273 |
| Protein | Taxonomy | zd 7288 (IC50) | guanfacine (IC50) |
|---|---|---|---|
| 5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | 1.453 | |
| Alpha-2A adrenergic receptor | Homo sapiens (human) | 0.134 | |
| Alpha-2B adrenergic receptor | Homo sapiens (human) | 0.249 | |
| Alpha-2C adrenergic receptor | Homo sapiens (human) | 6.447 | |
| 5-hydroxytryptamine receptor 2A | Homo sapiens (human) | 3.014 | |
| 5-hydroxytryptamine receptor 2C | Homo sapiens (human) | 1.453 | |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | 2.098 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Arnsten, AF; Brennan, A; Dudley, A; Duque, A; Mazer, JA; McCormick, DA; Nou, E; Paspalas, CD; Ramos, BP; Shu, Y; Simen, A; Vijayraghavan, S; Wang, M | 1 |
1 other study(ies) available for zd 7288 and guanfacine
| Article | Year |
|---|---|
Alpha2A-adrenoceptors strengthen working memory networks by inhibiting cAMP-HCN channel signaling in prefrontal cortex.
Topics: Adrenergic alpha-Agonists; Animals; Cyclic AMP; Cyclic Nucleotide-Gated Cation Channels; Dendritic Spines; Electrophysiology; Guanfacine; Ion Channels; Macaca mulatta; Male; Memory, Short-Term; Neurons; Prefrontal Cortex; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2 | 2007 |