zd 7288 has been researched along with colforsin in 21 studies
| Studies (zd 7288) | Trials (zd 7288) | Recent Studies (post-2010) (zd 7288) | Studies (colforsin) | Trials (colforsin) | Recent Studies (post-2010) (colforsin) |
|---|---|---|---|---|---|
| 382 | 0 | 137 | 13,460 | 46 | 1,298 |
| Protein | Taxonomy | zd 7288 (IC50) | colforsin (IC50) |
|---|---|---|---|
| nuclear receptor subfamily 0 group B member 1 | Homo sapiens (human) | 1.729 | |
| 5-hydroxytryptamine receptor 1A | Homo sapiens (human) | 0.041 | |
| Adenylate cyclase type 1 | Homo sapiens (human) | 0.0955 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 15 (71.43) | 29.6817 |
| 2010's | 6 (28.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Beaumont, V; Zucker, RS | 1 |
| Aghajanian, GK; Jolas, T; Nestler, EJ | 1 |
| Mellor, J; Nicoll, RA; Schmitz, D | 1 |
| Agmon, A; Wells, JE | 1 |
| Zhong, N; Zucker, RS | 1 |
| Beck, DR; Buvanendran, A; Kroin, JS; Topic, JE; Tuman, KJ; Watts, DE | 1 |
| Barstow, KL; Merriam, LA; Parsons, RL | 1 |
| Finlayson, PG; Shaikh, AG | 1 |
| Bie, B; Pan, ZZ; Peng, Y; Zhang, Y | 1 |
| Cox, CL; Govindaiah, G | 1 |
| Genlain, M; Godaux, E; Ris, L | 1 |
| Constantin, S; Wray, S | 1 |
| Dibattista, M; Grassi, F; Mazzatenta, A; Menini, A; Tirindelli, R | 1 |
| Cadiou, H; Mason, A; McNaughton, PA; Momin, A | 1 |
| Belmonte, C; Viana, F | 1 |
| Carloni, P; Cherubini, E; Giorgetti, A; Griguoli, M; Maul, A; Nguyen, C | 1 |
| Amodeo, FS; Brummett, CM; Hong, EK; Janda, AM; Lydic, R | 1 |
| Chetkovich, D; Golding, NL; Khurana, S; Lewis, AS; Liu, Z; Rosa, K | 1 |
| Hasselmo, ME; Heys, JG | 1 |
| Belluzzi, O; Borin, M; Fogli Iseppe, A; Gambardella, C; Pignatelli, A | 1 |
| Jiang, CY; Liu, T; Peng, SC; Wu, J; Xie, CN; Zhang, DY | 1 |
21 other study(ies) available for zd 7288 and colforsin
| Article | Year |
|---|---|
Enhancement of synaptic transmission by cyclic AMP modulation of presynaptic Ih channels.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Action Potentials; Animals; Astacoidea; Axons; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic Nucleotide-Gated Cation Channels; Electric Stimulation; Enzyme Inhibitors; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; In Vitro Techniques; Ion Channels; Muscles; Neuromuscular Junction; Phosphodiesterase Inhibitors; Potassium Channels; Presynaptic Terminals; Purinergic P1 Receptor Antagonists; Pyrimidines; Serotonin; Synaptic Transmission; Theophylline | 2000 |
Chronic morphine increases GABA tone on serotonergic neurons of the dorsal raphe nucleus: association with an up-regulation of the cyclic AMP pathway.
Topics: Adenylyl Cyclases; Analgesics, Opioid; Animals; Cardiovascular Agents; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Electrophysiology; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enzyme Inhibitors; Excitatory Amino Acid Agonists; gamma-Aminobutyric Acid; In Vitro Techniques; Interneurons; Isoquinolines; Male; Membrane Potentials; Morphine; N-Methylaspartate; Neural Inhibition; Periaqueductal Gray; Phenylephrine; Pyrimidines; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Serotonin; Substance Withdrawal Syndrome; Sulfonamides; Sympathomimetics; Tetrazoles; Tetrodotoxin; Thionucleotides | 2000 |
Mediation of hippocampal mossy fiber long-term potentiation by presynaptic Ih channels.
Topics: Adenylyl Cyclases; Animals; Benzazepines; Calcium; Cesium; Chlorides; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic Nucleotide-Gated Cation Channels; Dentate Gyrus; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; In Vitro Techniques; Ion Channels; Isoquinolines; Long-Term Potentiation; Membrane Potentials; Membrane Proteins; Models, Neurological; Mossy Fibers, Hippocampal; Nerve Tissue Proteins; Patch-Clamp Techniques; Potassium; Potassium Channels; Presynaptic Terminals; Pyramidal Cells; Pyrimidines; Rats; Rats, Sprague-Dawley; Sulfonamides; Synaptic Transmission | 2002 |
The role of the hyperpolarization-activated cationic current I(h) in the timing of interictal bursts in the neonatal hippocampus.
Topics: Animals; Animals, Newborn; Biological Clocks; Cardiovascular Agents; Cations; Colforsin; Computer Simulation; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; GABA Antagonists; GABA-A Receptor Antagonists; Hippocampus; In Vitro Techniques; Mice; Models, Neurological; Periodicity; Potassium Channel Blockers; Pyrimidines; Receptors, GABA-A; Seizures; Synaptic Transmission | 2003 |
Roles of Ca2+, hyperpolarization and cyclic nucleotide-activated channel activation, and actin in temporal synaptic tagging.
Topics: Actins; Animals; Astacoidea; Benzazepines; Bridged Bicyclo Compounds, Heterocyclic; Calcium; Colforsin; Cyclic AMP; Cyclic Nucleotide-Gated Cation Channels; Cytochalasin D; Electric Stimulation; In Vitro Techniques; Ion Channels; Long-Term Potentiation; Membrane Potentials; Motor Neurons; Neuromuscular Junction; Pyrimidines; Thiazoles; Thiazolidines; Time Factors | 2004 |
Clonidine prolongation of lidocaine analgesia after sciatic nerve block in rats Is mediated via the hyperpolarization-activated cation current, not by alpha-adrenoreceptors.
Topics: Adrenergic alpha-Agonists; Anesthetics, Local; Animals; Clonidine; Colforsin; Dose-Response Relationship, Drug; Drug Synergism; Epinephrine; In Vitro Techniques; Ion Channels; Lidocaine; Male; Nerve Block; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Sciatic Nerve | 2004 |
Pituitary adenylate cyclase-activating polypeptide enhances the hyperpolarization-activated nonselective cationic conductance, Ih, in dissociated guinea pig intracardiac neurons.
Topics: Action Potentials; Animals; Colforsin; Electric Conductivity; Female; Guinea Pigs; Heart; In Vitro Techniques; Male; Membrane Potentials; Myocardium; Nerve Growth Factors; Neurons; Neuropeptides; Neurotransmitter Agents; Pituitary Adenylate Cyclase-Activating Polypeptide; Pyrimidines | 2004 |
Excitability of auditory brainstem neurons, in vivo, is increased by cyclic-AMP.
Topics: Acoustic Stimulation; Adenylyl Cyclases; Analysis of Variance; Animals; Auditory Perception; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Electrophysiology; Excitatory Amino Acid Agonists; Glutamic Acid; Ion Channels; Male; Neurons; Olivary Nucleus; Pyrimidines; Rats; Rats, Long-Evans | 2005 |
cAMP-mediated mechanisms for pain sensitization during opioid withdrawal.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; 8-Bromo Cyclic Adenosine Monophosphate; Adenylyl Cyclases; Animals; Animals, Newborn; Behavior, Animal; Blotting, Western; Colforsin; Cyclic AMP; Dose-Response Relationship, Radiation; Drug Administration Schedule; Drug Interactions; Electric Stimulation; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Gene Expression Regulation; Imines; In Vitro Techniques; Isoquinolines; Male; Membrane Potentials; Microinjections; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Opioid-Related Disorders; Oxidoreductases; Pain; Pain Measurement; Patch-Clamp Techniques; Pyrimidines; Raphe Nuclei; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sulfonamides | 2005 |
Excitatory actions of dopamine via D1-like receptors in the rat lateral geniculate nucleus.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Action Potentials; Adrenergic alpha-Antagonists; Analysis of Variance; Anesthetics, Local; Animals; Animals, Newborn; Benzazepines; Bromocriptine; Carbazoles; Colforsin; Cyclic AMP; Dopamine; Dopamine Agonists; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Enzyme Inhibitors; Geniculate Bodies; In Vitro Techniques; Indoles; Neurons; Patch-Clamp Techniques; Prazosin; Pyrimidines; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Tetrodotoxin; Thionucleotides | 2005 |
Involvement of hyperpolarization-activated cation channels in synaptic modulation.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic Nucleotide-Gated Cation Channels; Excitatory Postsynaptic Potentials; Glutamic Acid; Hippocampus; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; Neural Pathways; Neurons; Phosphodiesterase Inhibitors; Potassium; Potassium Channel Blockers; Potassium Channels; Presynaptic Terminals; Pyrimidines; Rats; Rats, Wistar; Synaptic Membranes; Synaptic Transmission | 2007 |
Gonadotropin-releasing hormone-1 neuronal activity is independent of hyperpolarization-activated cyclic nucleotide-modulated channels but is sensitive to protein kinase a-dependent phosphorylation.
Topics: Adenylyl Cyclases; Animals; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic Nucleotide-Gated Cation Channels; Female; GABA-A Receptor Antagonists; Gonadotropin-Releasing Hormone; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; Immunohistochemistry; Mice; Neurons; Nitrogen Mustard Compounds; Phosphorylation; Potassium Channels; Pregnancy; Pyrimidines; Receptors, GABA-A; Reverse Transcriptase Polymerase Chain Reaction; Tissue Culture Techniques | 2008 |
Hyperpolarization-activated cyclic nucleotide-gated channels in mouse vomeronasal sensory neurons.
Topics: Adenine; Animals; Biophysical Phenomena; Biophysics; Cesium; Chlorides; Colforsin; Cyclic AMP; Cyclic Nucleotide-Gated Cation Channels; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Enzyme Inhibitors; Gene Expression Regulation; Imines; In Vitro Techniques; Membrane Potentials; Mice; Mice, Inbred C57BL; Neurons, Afferent; Patch-Clamp Techniques; Potassium Chloride; Pyrimidines; Vomeronasal Organ | 2008 |
Role of the hyperpolarization-activated current Ih in somatosensory neurons.
Topics: Action Potentials; Animals; Animals, Newborn; Cell Size; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic Nucleotide-Gated Cation Channels; Dinoprostone; Electric Stimulation; Ganglia, Spinal; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; Isoquinolines; Menthol; Mice; Mice, Inbred Strains; Mice, Knockout; Potassium Channel Blockers; Potassium Channels; Protein Kinase Inhibitors; Pyrimidines; Rats; Rats, Wistar; Sensory Receptor Cells; Sulfonamides; TRPM Cation Channels | 2008 |
Funny currents are becoming serious players in nociceptor's sensitization.
Topics: Action Potentials; Animals; Cell Size; Colforsin; Cyclic AMP; Cyclic Nucleotide-Gated Cation Channels; Dinoprostone; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; Mice; Mice, Knockout; Nociceptors; Potassium Channel Blockers; Potassium Channels; Pyrimidines; Rats; Sensory Receptor Cells | 2008 |
Nicotine blocks the hyperpolarization-activated current Ih and severely impairs the oscillatory behavior of oriens-lacunosum moleculare interneurons.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Analysis of Variance; Animals; Biological Clocks; Cardiovascular Agents; Colforsin; Cyclic Nucleotide-Gated Cation Channels; Dihydro-beta-Erythroidine; Dose-Response Relationship, Drug; Electric Stimulation; Excitatory Amino Acid Antagonists; Female; gamma-Aminobutyric Acid; Green Fluorescent Proteins; Hippocampus; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; In Vitro Techniques; Interneurons; Male; Mecamylamine; Mice; Mice, Transgenic; Models, Biological; Models, Molecular; Neural Inhibition; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Patch-Clamp Techniques; Potassium Channels; Pyrimidines; Somatostatin | 2010 |
Perineural dexmedetomidine added to ropivacaine for sciatic nerve block in rats prolongs the duration of analgesia by blocking the hyperpolarization-activated cation current.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Amides; Analgesia; Anesthetics, Local; Animals; Behavior, Animal; Colforsin; Cyclic Nucleotide-Gated Cation Channels; Dexmedetomidine; Dose-Response Relationship, Drug; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; Hypnotics and Sedatives; Idazoxan; Male; Nerve Block; Pain Measurement; Potassium Channel Blockers; Potassium Channels; Prazosin; Pyrimidines; Rats; Rats, Sprague-Dawley; Ropivacaine; Sciatic Nerve | 2011 |
An essential role for modulation of hyperpolarization-activated current in the development of binaural temporal precision.
Topics: Age Factors; Analysis of Variance; Androstadienes; Animals; Biophysical Phenomena; Bucladesine; Colforsin; Cyclic Nucleotide-Gated Cation Channels; Electric Stimulation; Enzyme Inhibitors; Female; Gene Expression Regulation, Developmental; Gerbillinae; Imidazoles; In Vitro Techniques; Ion Channel Gating; Male; Neurons; Olivary Nucleus; Patch-Clamp Techniques; Pyridines; Pyrimidines; Wortmannin | 2012 |
Neuromodulation of I(h) in layer II medial entorhinal cortex stellate cells: a voltage-clamp study.
Topics: Animals; Animals, Newborn; Anthracenes; Atropine; Biophysical Phenomena; Carbachol; Cardiotonic Agents; Cholinergic Antagonists; Colforsin; Cyclic AMP; Cyclic Nucleotide-Gated Cation Channels; Electric Stimulation; Entorhinal Cortex; Female; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; In Vitro Techniques; Male; Membrane Potentials; Neurons; Neurotransmitter Agents; Patch-Clamp Techniques; Potassium Channels; Pyrimidines; Rats; Rats, Long-Evans; Sodium Channel Blockers; Tetrodotoxin; Time Factors | 2012 |
The h-current in periglomerular dopaminergic neurons of the mouse olfactory bulb.
Topics: 1-Methyl-3-isobutylxanthine; Adrenergic alpha-Agonists; Animals; Benzazepines; Colforsin; Cyclic AMP; Cyclic Nucleotide-Gated Cation Channels; Dopamine; Dopaminergic Neurons; Green Fluorescent Proteins; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; Ivabradine; Kinetics; Membrane Potentials; Mice; Mice, Inbred C57BL; Mice, Transgenic; Norepinephrine; Olfactory Bulb; Patch-Clamp Techniques; Potassium Channels; Pyrimidines; Rats; Tyrosine 3-Monooxygenase | 2013 |
Contribution of presynaptic HCN channels to excitatory inputs of spinal substantia gelatinosa neurons.
Topics: Adjuvants, Immunologic; Animals; Colforsin; Excitatory Postsynaptic Potentials; Gene Expression Regulation; Glutamate Decarboxylase; Green Fluorescent Proteins; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Pyrimidines; Rats; Rats, Sprague-Dawley; Sensory Receptor Cells; Sodium Channel Blockers; Substantia Gelatinosa; Tetrodotoxin; Vesicular Glutamate Transport Protein 2 | 2017 |