Compounds > zardaverine
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zardaverine and 1-methyl-3-isobutylxanthine

zardaverine has been researched along with 1-methyl-3-isobutylxanthine in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (54.55)18.2507
2000's2 (18.18)29.6817
2010's3 (27.27)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Chen, G; Ke, H; Kunz, S; Martinelli, S; Robinson, H; Seebeck, T; Wan, Y; Wang, H1
de Esch, IJ; de Graaf, C; Jansen, C; Kanev, GK; Kooistra, AJ; Leurs, R1
Allart-Simon, I; Barberot, C; Bentaher, A; Bouillon, JP; Gérard, S; Hénon, E; Laronze-Cochard, M; Malleret, L; Médebielle, M; Moniot, A; Sapi, J; Velard, F; Yegorova, T1
Galvan, M; Schudt, C1
Gaal, L; Illes, P; Schudt, C1
Dent, G; Magnussen, H; Nakashima, M; Rabe, KF; Schudt, C; Tenor, H1
Hatzelmann, A; Schudt, C; Tenor, H1
Downing, GJ; Poisner, AM1
Dent, G; Liebig, S; Magnussen, H; Rabe, KF; Schudt, C; Tenor, H1
Branscheid, D; Dent, G; Magnussen, H; Rabe, KF; Rühlmann, E; Schmidt, DT; Watson, N1

Other Studies

11 other study(ies) available for zardaverine and 1-methyl-3-isobutylxanthine

ArticleYear
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Biological and structural characterization of Trypanosoma cruzi phosphodiesterase C and Implications for design of parasite selective inhibitors.
    The Journal of biological chemistry, 2012, Apr-06, Volume: 287, Issue:15

    Topics: Amino Acid Sequence; Bridged Bicyclo Compounds, Heterocyclic; Catalytic Domain; Conserved Sequence; Crystallography, X-Ray; Drug Design; Kinetics; Molecular Sequence Data; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Protein Binding; Protein Structure, Secondary; Protozoan Proteins; Recombinant Proteins; Saccharomyces cerevisiae; Sulfonamides; Surface Properties; Trypanosoma cruzi

2012
PDEStrIAn: A Phosphodiesterase Structure and Ligand Interaction Annotated Database As a Tool for Structure-Based Drug Design.
    Journal of medicinal chemistry, 2016, Aug-11, Volume: 59, Issue:15

    Topics: Databases, Protein; Dose-Response Relationship, Drug; Drug Design; Humans; Ligands; Models, Molecular; Molecular Structure; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Structure-Activity Relationship

2016
Synthesis and biological evaluation of pyridazinone derivatives as potential anti-inflammatory agents.
    European journal of medicinal chemistry, 2018, Feb-25, Volume: 146

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Cyclic Nucleotide Phosphodiesterases, Type 4; Dose-Response Relationship, Drug; Humans; Models, Molecular; Molecular Structure; Neutrophils; Phosphodiesterase 4 Inhibitors; Pyridazines; Structure-Activity Relationship

2018
Actions of the phosphodiesterase inhibitor zardaverine on guinea-pig ventricular muscle.
    Naunyn-Schmiedeberg's archives of pharmacology, 1990, Volume: 342, Issue:2

    Topics: 1-Methyl-3-isobutylxanthine; Action Potentials; Animals; Dogs; Guinea Pigs; Heart; In Vitro Techniques; Isoenzymes; Male; Myocardial Contraction; Papillary Muscles; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Potassium; Pyridazines; Trachea

1990
Effects of phosphodiesterase inhibition on the excitability of hippocampal pyramidal neurons in vitro.
    European journal of pharmacology, 1991, Sep-04, Volume: 202, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Animals; Electric Stimulation; Evoked Potentials; Hippocampus; In Vitro Techniques; Isoproterenol; Male; Neurons; Phosphodiesterase Inhibitors; Pyramidal Tracts; Pyridazines; Pyrrolidinones; Rats; Rats, Inbred Strains; Rolipram

1991
Identification of PDE isozymes in human pulmonary artery and effect of selective PDE inhibitors.
    The American journal of physiology, 1994, Volume: 266, Issue:5 Pt 1

    Topics: 1-Methyl-3-isobutylxanthine; Adult; Aged; Antihypertensive Agents; Carbachol; Colforsin; Cytosol; Dinoprost; Dose-Response Relationship, Drug; Female; Humans; Isoenzymes; Kinetics; Lung Neoplasms; Male; Middle Aged; Muscle Contraction; Muscle Relaxation; Muscle Tonus; Muscle, Smooth, Vascular; Nitroprusside; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Pulmonary Artery; Purinones; Pyridazines; Pyrrolidinones; Rolipram

1994
Differential effects of non-selective and selective phosphodiesterase inhibitors on human eosinophil functions.
    British journal of pharmacology, 1995, Volume: 114, Issue:4

    Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Adrenergic beta-Antagonists; Benzamides; Blood Proteins; Cell Separation; Complement C5a; Cyclic Nucleotide Phosphodiesterases, Type 4; Electromagnetic Fields; Eosinophil Granule Proteins; Eosinophil-Derived Neurotoxin; Eosinophils; Humans; Inflammation Mediators; Luminescent Measurements; Naphthyridines; Neurotoxins; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Pyridazines; Pyridines; Pyrrolidinones; Ribonuclease, Pancreatic; Ribonucleases; Rolipram; Theophylline

1995
Stimulation of placental prorenin secretion by selective inhibition of cyclic nucleotide phosphodiesterases.
    Biochemical pharmacology, 1995, May-26, Volume: 49, Issue:11

    Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Chorionic Gonadotropin; Culture Media; Culture Techniques; Cyclic AMP; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Precursors; Humans; Placenta; Protein Kinases; Pyridazines; Quinolones; Renin

1995
Phosphodiesterase isozymes modulating inherent tone in human airways: identification and characterization.
    The American journal of physiology, 1993, Volume: 264, Issue:5 Pt 1

    Topics: 1-Methyl-3-isobutylxanthine; 2',3'-Cyclic-Nucleotide Phosphodiesterases; Adult; Aged; Bucladesine; Colforsin; Dibutyryl Cyclic GMP; Dose-Response Relationship, Drug; Female; Forced Expiratory Volume; Humans; In Vitro Techniques; Isoenzymes; Lung; Lung Neoplasms; Male; Middle Aged; Muscle Relaxation; Muscle Tonus; Muscle, Smooth; Nitroprusside; Purinones; Pyrazines; Pyridazines; Pyrrolidinones; Rolipram; Vital Capacity

1993
The effect of selective and non-selective phosphodiesterase inhibitors on allergen- and leukotriene C(4)-induced contractions in passively sensitized human airways.
    British journal of pharmacology, 2000, Volume: 131, Issue:8

    Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Antigens, Dermatophagoides; Benzamides; Bronchi; Bronchodilator Agents; Cyclic Nucleotide Phosphodiesterases, Type 3; Cyclic Nucleotide Phosphodiesterases, Type 4; Dose-Response Relationship, Drug; Glycoproteins; Histamine; Humans; In Vitro Techniques; Leukotriene C4; Lung Neoplasms; Muscle Contraction; Phosphodiesterase Inhibitors; Pyridazines; Pyridines; Rolipram; Theophylline

2000