zaragozic-acid-c and lactacystin

zaragozic-acid-c has been researched along with lactacystin* in 1 studies

Reviews

1 review(s) available for zaragozic-acid-c and lactacystin

Article	Year
[Development of Synthetic Strategies for Densely Oxygenated Natural Products: Total Synthesis of Lactacystin and Zaragozic Acid C Using Photochemical C(sp Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2019, Volume: 139, Issue:5 This review describes two novel synthetic routes from (S)-pyroglutaminol to (+)-lactacystin, a potent inhibitor of the 20S proteasome and from d-gluconolactone derivative to zaragozic acid C, a potent squalene synthase inhibitor. In lactacystin synthesis, the photoinduced intermolecular C(sp Topics: Acetylcysteine; Acylation; Alkylation; Biological Products; Bridged Bicyclo Compounds, Heterocyclic; Carbon; Enzyme Inhibitors; Farnesyl-Diphosphate Farnesyltransferase; Free Radicals; Gluconates; Lactones; Oxidation-Reduction; Oxygen; Photochemical Processes; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Pyrroles; Stereoisomerism	2019

Article

Year

[Development of Synthetic Strategies for Densely Oxygenated Natural Products: Total Synthesis of Lactacystin and Zaragozic Acid C Using Photochemical C(sp

Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2019, Volume: 139, Issue:5

This review describes two novel synthetic routes from (S)-pyroglutaminol to (+)-lactacystin, a potent inhibitor of the 20S proteasome and from d-gluconolactone derivative to zaragozic acid C, a potent squalene synthase inhibitor. In lactacystin synthesis, the photoinduced intermolecular C(sp

Topics: Acetylcysteine; Acylation; Alkylation; Biological Products; Bridged Bicyclo Compounds, Heterocyclic; Carbon; Enzyme Inhibitors; Farnesyl-Diphosphate Farnesyltransferase; Free Radicals; Gluconates; Lactones; Oxidation-Reduction; Oxygen; Photochemical Processes; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Pyrroles; Stereoisomerism

2019