zaprinast has been researched along with avanafil* in 2 studies
2 other study(ies) available for zaprinast and avanafil
| Article | Year |
|---|---|
Can zaprinast and avanafil induce the levels of angiogenesis, bone morphogenic protein 2, 4 and 7 in kidney of ovariectomised rats?
This study investigated effects of zaprinast and avanafil on angiogenesis, vascular endothelial growth factor (VEGF), bone morphogenic protein (BMP) 2, 4 and 7.. VEGF, BMP2, 4 and 7 levels in OVX + zaprinast and especially OVX + avanafil groups were higher than the sham and OVX (. Zaprinast and avanafil induced BMP2, 4 and 7 levels synergistically with increased VEGF and angiogenesis in renal tissue. Topics: Animals; Bone Morphogenetic Protein 2; Bone Morphogenetic Protein 4; Bone Morphogenetic Protein 7; Bone Morphogenetic Proteins; Female; Kidney; Neovascularization, Physiologic; Ovariectomy; Purinones; Pyrimidines; Rats; Vascular Endothelial Growth Factor A | 2022 |
Effects of the Phosphodiesterase-5 (PDE-5) Inhibitors, Avanafil and Zaprinast, on Bone Remodeling and Oxidative Damage in a Rat Model of Glucocorticoid-Induced Osteoporosis.
Topics: Animals; Bone Density; Bone Remodeling; Cyclic Nucleotide Phosphodiesterases, Type 5; Dexamethasone; Disease Models, Animal; Dose-Response Relationship, Drug; Glucocorticoids; Male; Osteoporosis; Oxidation-Reduction; Oxidative Stress; Phosphodiesterase 5 Inhibitors; Purinones; Pyrimidines; Rats | 2018 |