Page last updated: 2024-08-24

zanamivir and rimantadine

zanamivir has been researched along with rimantadine in 73 studies

Research

Studies (73)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (8.22)18.2507
2000's50 (68.49)29.6817
2010's15 (20.55)24.3611
2020's2 (2.74)2.80

Authors

AuthorsStudies
Batta, G; Bereczki, I; Borbás, A; Fejes, Z; Herczegh, P; Kiss-Szikszai, A; Naesens, L; Ostorházi, E; Rőth, E; Rozgonyi, F; Sipos, A; Török, Z1
Cesur, N; Cesur, Z; Göktaş, F; Naesens, L; Vanderlinden, E1
Fernández, R; Font-Bardia, M; Miquet, S; Naesens, L; Torres, E; Vanderlinden, E; Vázquez, S1
Batta, G; Bereczki, I; Borbás, A; Dobray, L; Herczegh, P; Kéki, S; Kicsák, M; Naesens, L; Nikodém, ÉN; Ostorházi, E; Rozgonyi, F; Vanderlinden, E1
Cichero, E; Costi, MP; Gazzarrini, S; Loddo, R; Moroni, A; Naesens, L; Santucci, M; Tasso, B; Tonelli, M1
Cichero, E; Costi, MP; Francesconi, V; Giordanetto, F; Giovannini, L; Naesens, L; Santucci, M; Tonelli, M1
Batta, G; Borbás, A; Csávás, M; Herczegh, P; Kelemen, V; Le Thai, S; Naesens, L; Rőth, E; Stevaert, A; Szűcs, Z; Vanderlinden, E1
Andrei, G; Cazin, I; Harej, A; Klobučar, M; Macan, AM; Pavelić, K; Pavelić, SK; Raić-Malić, S; Schols, D; Snoeck, R; Stepanić, V1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Hayden, FG; Madren, LK; Rollins, BS1
Couch, RB2
Ambrozaitis, A; Drinka, P; Gravenstein, M; Gravenstein, S; Jones, HH; Krause, P; Povinelli, L; Powers, D; Schilling, M; Shult, P1
Mossad, SB2
Silagy, CA1
Deeks, J; Demicheli, V; Jefferson, T; Rivetti, D1
Goldman, MP; Long, JK; Mossad, SB1
Ashley, JV; Gum, KD; Montalto, NJ1
Rosen, DS1
Hayden, FG2
Fleming, DM1
Preboth, M1
Holdiness, MR1
Gross, PA1
Farr, BM; Hall, KK; Hayden, FG; Salgado, CD1
Bridges, CB; Cox, NJ; Fukuda, K; Singleton, JA; Uyeki, TM1
Prober, CG1
Englund, JA1
Leong, MA; Simmen, KA; Wagaman, PC1
Clements, DA; Hamilton, JD; Huber, J; Lee, PY; Matchar, DB; Peterson, ED1
Davidson, HE; Gravenstein, S1
Uyeki, T; Winquist, A1
Dumyati, G; Falsey, AR1
Balasingam, S; Bossuyt, S; Lambkin, R; Mann, A; Novelli, P; Oxford, JS1
Mitamura, K1
Kirkbride, HA; Watson, J1
Elliott, M; Gnann, JW; Hayden, FG; Ison, MG; Nagy-Agren, S; Paya, C; Steigbigel, R; Treannor, J; Weiss, HL1
Bellantonio, S; Rose, DN; Rothberg, MB1
Pegram, PS; Williamson, JC1
Lu, Q1
Härtl, A; Sauerbrei, A; Stelzner, A; Wutzler, P1
Fagan, HB; Moeller, AH1
Hansen, L2
Fang, HB; Govorkova, EA; Tan, M; Webster, RG1
Brandstaedt, A; Haertl, A; Sauerbrei, A; Schmidtke, M; Wutzler, P1
Barr, IG; Deed, N; Hurt, AC; Iannello, P; Komadina, N; Tomasov, C1
Hayden, FG; Pavia, AT1
Brydak, LB; Gawryluk, D; Machała, M; Wiatr, E1
Lynch, JP; Walsh, EE1
Cummings, JE; Kelly, EB; Raimer, SS; Snyder, RR1
Wesseling, G1
Worrall, G1
Nüesch, R1
Monto, AS1
Balish, A; Bright, RA; Deyde, VM; Gubareva, LV; Klimov, AI; Lindstrom, S; Nguyen, T; Shu, B1
Jefferson, T1
Oxford, JS1
Barr, IG; Holien, JK; Hurt, AC; Parker, MW1
Beekmann, SE; Dharan, NJ; Finelli, L; Fiore, A; Fry, AM; Polgreen, PM; Uyeki, TM1
Li, JF; Shen, JS; Xiong, RS; Zhang, Q; Zhao, QJ1
Arnold, K; Baumbach, J; Bennett, NM; Doshi, S; Finelli, L; Fry, AM; Gershman, K; Hancock, EB; Kamimoto, L; Lynfield, R; Morin, C; Perez, A; Reingold, A; Ryan, P; Schaffner, W; Thomas, A; Yousey-Hindes, K; Zansky, S1
Akl, EA; Alonso-Coello, P; Brozek, J; Chen, YL; Cheung, A; Flottorp, SA; Hopkins, JP; Hovhannisyan, G; Hsu, J; Ivanova, L; Mustafa, R; Saeterdal, I; Santesso, N; Schünemann, HJ; Smaill, F; Tian, J; Uyeki, TM; Wong, AD1
Król, E; Rychłowska, M; Szewczyk, B1
Li, F; Ma, C; Wang, J1
Atkins, E; Bao, P; Barclay, WS; Bentham, M; Claridge, JK; Cook, GP; Elderfield, R; Evans, S; Foster, R; Foster, TL; Goldhill, DH; Griffin, S; Kankanala, J; Loundras, E; McKimmie, CS; Pingen, M; Schnell, JR; Scott, C; Simmons, K; Stilwell, PR; Targett-Adams, P; Tathineni, R; Thompson, J1

Reviews

34 review(s) available for zanamivir and rimantadine

ArticleYear
Underused options for preventing and treating influenza.
    Cleveland Clinic journal of medicine, 1999, Volume: 66, Issue:1

    Topics: Adolescent; Adult; Aged; Amantadine; Antiviral Agents; Child; Child, Preschool; Drug Administration Routes; Female; Guanidines; Humans; Influenza Vaccines; Influenza, Human; Male; Middle Aged; Orthomyxoviridae; Pyrans; Ribavirin; Rimantadine; Sialic Acids; Zanamivir

1999
Prevention and early treatment of influenza in healthy adults.
    Vaccine, 2000, Jan-06, Volume: 18, Issue:11-12

    Topics: Adolescent; Adult; Amantadine; Antiviral Agents; Cost-Benefit Analysis; Guanidines; Humans; Influenza Vaccines; Influenza, Human; Middle Aged; Pyrans; Rimantadine; Sialic Acids; Zanamivir

2000
Measures for control of influenza.
    PharmacoEconomics, 1999, Volume: 16 Suppl 1

    Topics: Amantadine; Amines; Antiviral Agents; Enzyme Inhibitors; Guanidines; Humans; Influenza A virus; Influenza Vaccines; Influenza, Human; Oseltamivir; Pyrans; Rimantadine; Sialic Acids; Zanamivir

1999
Antiviral agents for treating influenza.
    Cleveland Clinic journal of medicine, 2000, Volume: 67, Issue:2

    Topics: Acetamides; Amantadine; Antiviral Agents; Drug Administration Schedule; Guanidines; Humans; Influenza A virus; Influenza B virus; Influenza Vaccines; Influenza, Human; Oseltamivir; Pyrans; Rimantadine; Sialic Acids; Zanamivir

2000
Updated treatment for influenza A and B.
    American family physician, 2000, Dec-01, Volume: 62, Issue:11

    Topics: Acetamides; Amantadine; Antiviral Agents; Clinical Trials as Topic; Enzyme Inhibitors; Guanidines; Humans; Influenza, Human; Neuraminidase; Oseltamivir; Pyrans; Rimantadine; Sialic Acids; Treatment Outcome; Zanamivir

2000
Influenza virus and rhinovirus-related otitis media: potential for antiviral intervention.
    Vaccine, 2000, Dec-08, Volume: 19 Suppl 1

    Topics: Acetamides; Adult; Anti-Bacterial Agents; Antiviral Agents; Child; Child, Preschool; Clinical Trials as Topic; Eustachian Tube; Guanidines; Humans; Infant; Influenza A virus; Influenza B virus; Influenza, Human; Interferon-beta; Oseltamivir; Otitis Media; Otitis Media with Effusion; Picornaviridae Infections; Piperidines; Pressure; Pyrans; Pyridazines; Respiratory Tract Infections; Rhinovirus; Rimantadine; Sialic Acids; Superinfection; Virus Replication; Zanamivir

2000
Managing influenza: amantadine, rimantadine and beyond.
    International journal of clinical practice, 2001, Volume: 55, Issue:3

    Topics: Adolescent; Adult; Aged; Amantadine; Antiviral Agents; Child; Child, Preschool; Guanidines; Humans; Infant; Influenza A virus; Influenza B virus; Influenza Vaccines; Influenza, Human; Middle Aged; Neuraminidase; Pyrans; Rimantadine; Sialic Acids; Zanamivir

2001
Adverse cutaneous reactions to influenza vaccinations and chemotherapy.
    International journal of dermatology, 2001, Volume: 40, Issue:7

    Topics: Acetamides; Amantadine; Antiviral Agents; Drug Eruptions; Drug-Related Side Effects and Adverse Reactions; Guanidines; Humans; Influenza Vaccines; Influenza, Human; Orthomyxoviridae; Oseltamivir; Pyrans; Rimantadine; Sialic Acids; Skin; Zanamivir

2001
Vaccines for pneumonia and new antiviral therapies.
    The Medical clinics of North America, 2001, Volume: 85, Issue:6

    Topics: Acetamides; Adult; Aged; Amantadine; Antiviral Agents; Centers for Medicare and Medicaid Services, U.S.; Child; Global Health; Guanidines; Health Priorities; Humans; Incidence; Influenza Vaccines; Joint Commission on Accreditation of Healthcare Organizations; Morbidity; Neuraminidase; Oseltamivir; Patient Selection; Pneumococcal Vaccines; Pneumonia; Primary Prevention; Pyrans; Rimantadine; Safety; Sialic Acids; United States; Vaccination; Zanamivir

2001
Perspectives on antiviral use during pandemic influenza.
    Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 2001, Dec-29, Volume: 356, Issue:1416

    Topics: Acetamides; Amantadine; Antiviral Agents; Chemoprevention; Disease Outbreaks; Drug Resistance, Multiple, Viral; Drug Tolerance; Guanidines; Humans; Influenza A virus; Influenza, Human; Oseltamivir; Pyrans; Rimantadine; Sialic Acids; Zanamivir

2001
Influenza in the acute hospital setting.
    The Lancet. Infectious diseases, 2002, Volume: 2, Issue:3

    Topics: Acetamides; Amantadine; Antiviral Agents; Cross Infection; Disease Outbreaks; Guanidines; Hospitals; Humans; Influenza Vaccines; Influenza, Human; Nursing Staff, Hospital; Oseltamivir; Pyrans; Rimantadine; Sialic Acids; Vaccination; Virginia; Zanamivir

2002
Antiviral therapy for influenza virus infections.
    Seminars in pediatric infectious diseases, 2002, Volume: 13, Issue:1

    Topics: Acetamides; Age Factors; Amantadine; Antiviral Agents; Child; Clinical Trials as Topic; Global Health; Guanidines; Humans; Influenza, Human; Oseltamivir; Pyrans; Rimantadine; Sialic Acids; Zanamivir

2002
Antiviral therapy of influenza.
    Seminars in pediatric infectious diseases, 2002, Volume: 13, Issue:2

    Topics: Acetamides; Administration, Inhalation; Administration, Oral; Adult; Amantadine; Antiviral Agents; Child; Drug Resistance, Viral; Guanidines; Humans; Infant; Influenza, Human; Orthomyxoviridae; Oseltamivir; Pyrans; Rimantadine; Sialic Acids; Zanamivir

2002
Influenza.
    Clinical evidence, 2002, Issue:7

    Topics: Acetamides; Administration, Inhalation; Administration, Oral; Adult; Amantadine; Antiviral Agents; Child; Guanidines; Humans; Influenza, Human; Oseltamivir; Pyrans; Randomized Controlled Trials as Topic; Rimantadine; Sialic Acids; Treatment Outcome; Zanamivir

2002
Antivirals for influenza: what is their role in the older patient?
    Drugs & aging, 2002, Volume: 19, Issue:10

    Topics: Acetamides; Aged; Amantadine; Antiviral Agents; Drug Resistance, Viral; Guanidines; Humans; Influenza, Human; Oseltamivir; Practice Guidelines as Topic; Pyrans; Rimantadine; Sialic Acids; Zanamivir

2002
Treatment of epidemic and pandemic influenza with neuraminidase and M2 proton channel inhibitors.
    Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 2003, Volume: 9, Issue:1

    Topics: Acetamides; Amantadine; Antiviral Agents; Clinical Trials as Topic; Disease Outbreaks; Endemic Diseases; Enzyme Inhibitors; Guanidines; Humans; Influenza, Human; Neuraminidase; Oseltamivir; Pyrans; Rimantadine; Sialic Acids; Viral Matrix Proteins; Zanamivir

2003
[Antiviral agents for influenza].
    Nihon rinsho. Japanese journal of clinical medicine, 2003, Volume: 61 Suppl 2

    Topics: Acetamides; Age Factors; Amantadine; Antiviral Agents; Drug Resistance, Viral; Guanidines; Humans; Influenza A virus; Influenza, Human; Neuraminidase; Oseltamivir; Pyrans; Rimantadine; Sialic Acids; Viral Matrix Proteins; Zanamivir

2003
Review of the use of neuraminidase inhibitors for prophylaxis of influenza.
    Communicable disease and public health, 2003, Volume: 6, Issue:2

    Topics: Acetamides; Amantadine; Antiviral Agents; Enzyme Inhibitors; Guanidines; Health Planning; Humans; Influenza, Human; Neuraminidase; Oseltamivir; Practice Guidelines as Topic; Pyrans; Rimantadine; Sialic Acids; Zanamivir

2003
Neuraminidase inhibitors in patients with underlying airways disease.
    American journal of respiratory medicine : drugs, devices, and other interventions, 2002, Volume: 1, Issue:2

    Topics: Acetamides; Amantadine; Antiviral Agents; Asthma; Bronchial Spasm; Comorbidity; Guanidines; Humans; Influenza, Human; Neuraminidase; Oseltamivir; Product Surveillance, Postmarketing; Pulmonary Disease, Chronic Obstructive; Pyrans; Rimantadine; Risk Factors; Sialic Acids; Zanamivir

2002
What is the best antiviral agent for influenza infection?
    American family physician, 2004, Oct-01, Volume: 70, Issue:7

    Topics: Acetamides; Administration, Oral; Adult; Amantadine; Antiviral Agents; Child; Contraindications; Evidence-Based Medicine; Family Practice; Guanidines; Humans; Influenza A virus; Influenza, Human; Oseltamivir; Pyrans; Rimantadine; Sialic Acids; Zanamivir

2004
Influenza.
    Clinical evidence, 2003, Issue:10

    Topics: Acetamides; Adult; Amantadine; Antiviral Agents; Guanidines; Humans; Influenza A virus; Influenza B virus; Influenza, Human; Oseltamivir; Pyrans; Rimantadine; Sialic Acids; Zanamivir

2003
Influenza.
    Clinical evidence, 2004, Issue:12

    Topics: Acetamides; Adult; Amantadine; Antiviral Agents; Guanidines; Humans; Influenza A virus; Influenza B virus; Influenza, Human; Oseltamivir; Pyrans; Rimantadine; Sialic Acids; Zanamivir

2004
Which agents should we use to treat and prevent influenza in 2006-2007?
    Cleveland Clinic journal of medicine, 2006, Volume: 73, Issue:11

    Topics: Amantadine; Antiviral Agents; Drug Resistance, Viral; Humans; Influenza, Human; Neuraminidase; Oseltamivir; Rimantadine; Zanamivir

2006
Antiviral therapy and prophylaxis for influenza in children.
    Pediatrics, 2007, Volume: 119, Issue:4

    Topics: Adamantane; Amantadine; Antiviral Agents; Child; Child, Preschool; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Infant; Influenza, Human; Male; Oseltamivir; Primary Prevention; Prospective Studies; Randomized Controlled Trials as Topic; Rimantadine; Risk Assessment; Severity of Illness Index; Treatment Outcome; Zanamivir

2007
Influenza: evolving strategies in treatment and prevention.
    Seminars in respiratory and critical care medicine, 2007, Volume: 28, Issue:2

    Topics: Aged; Amantadine; Antiviral Agents; Centers for Disease Control and Prevention, U.S.; Child, Preschool; Humans; Infant; Influenza A virus; Influenza B virus; Influenza Vaccines; Influenza, Human; Oseltamivir; Practice Guidelines as Topic; Ribavirin; Rimantadine; United States; Zanamivir

2007
Occasional review: influenza in COPD: pathogenesis, prevention, and treatment.
    International journal of chronic obstructive pulmonary disease, 2007, Volume: 2, Issue:1

    Topics: Amantadine; Antiviral Agents; Humans; Influenza Vaccines; Influenza, Human; Oseltamivir; Pulmonary Disease, Chronic Obstructive; Rimantadine; Zanamivir

2007
[Antiviral treatment of influenza in humans].
    Therapeutische Umschau. Revue therapeutique, 2007, Volume: 64, Issue:11

    Topics: Amantadine; Animals; Antiviral Agents; Clinical Trials as Topic; Disease Outbreaks; Drug Resistance, Viral; Humans; Influenza A virus; Influenza, Human; Neuraminidase; Oseltamivir; Rimantadine; Virus Replication; Virus Shedding; Zanamivir

2007
Influenza.
    BMJ clinical evidence, 2009, Mar-12, Volume: 2009

    Topics: Acute Disease; Administration, Inhalation; Humans; Incidence; Influenza Vaccines; Influenza, Human; Oseltamivir; Rimantadine; Zanamivir

2009
Antivirals for the treatment and prevention of epidemic and pandemic influenza.
    Influenza and other respiratory viruses, 2007, Volume: 1, Issue:1

    Topics: Amantadine; Antiviral Agents; Chemoprevention; Disease Outbreaks; Drug Resistance, Viral; Humans; Influenza, Human; Oseltamivir; Rimantadine; Zanamivir

2007
[Research progress of anti-influenza virus agents].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2010, Volume: 45, Issue:3

    Topics: Acids, Carbocyclic; Amantadine; Antiviral Agents; Cyclopentanes; Guanidines; Humans; Indoles; Influenza, Human; Neuraminidase; Orthomyxoviridae; Oseltamivir; Pyrrolidines; Rimantadine; Structure-Activity Relationship; Viral Matrix Proteins; Zanamivir

2010
Antiviral drugs for influenza.
    The Medical letter on drugs and therapeutics, 2012, Jan-09, Volume: 54, Issue:1381

    Topics: Adult; Amantadine; Antiviral Agents; Child; Female; Humans; Influenza Vaccines; Influenza, Human; Neuraminidase; Oseltamivir; Pregnancy; Rimantadine; Zanamivir

2012
Antivirals for treatment of influenza: a systematic review and meta-analysis of observational studies.
    Annals of internal medicine, 2012, Apr-03, Volume: 156, Issue:7

    Topics: Administration, Inhalation; Administration, Oral; Amantadine; Antiviral Agents; Confounding Factors, Epidemiologic; Hospitalization; Humans; Influenza, Human; Oseltamivir; Rimantadine; Treatment Outcome; Zanamivir

2012
Antivirals--current trends in fighting influenza.
    Acta biochimica Polonica, 2014, Volume: 61, Issue:3

    Topics: Amantadine; Antiviral Agents; Disease Outbreaks; Drug Therapy, Combination; Enzyme Inhibitors; Humans; Influenza A virus; Influenza, Human; Neuraminidase; Oseltamivir; Rimantadine; Viral Matrix Proteins; Zanamivir

2014
Inhibitors targeting the influenza virus hemagglutinin.
    Current medicinal chemistry, 2015, Volume: 22, Issue:11

    Topics: Amantadine; Antiviral Agents; Enzyme Inhibitors; Hemagglutinin Glycoproteins, Influenza Virus; Neuraminidase; Orthomyxoviridae; Oseltamivir; Rimantadine; Zanamivir

2015

Trials

2 trial(s) available for zanamivir and rimantadine

ArticleYear
Efficacy of zanamivir for chemoprophylaxis of nursing home influenza outbreaks.
    Vaccine, 1998, Volume: 16, Issue:18

    Topics: Aged; Antiviral Agents; Disease Outbreaks; Female; Guanidines; Humans; Influenza A virus; Influenza B virus; Influenza, Human; Male; Nursing Homes; Prospective Studies; Pyrans; Random Allocation; Rimantadine; Sialic Acids; Treatment Outcome; Wisconsin; Zanamivir

1998
Safety and efficacy of nebulized zanamivir in hospitalized patients with serious influenza.
    Antiviral therapy, 2003, Volume: 8, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antiviral Agents; Double-Blind Method; Drug Resistance, Viral; Drug Therapy, Combination; Female; Guanidines; Humans; Influenza, Human; Male; Middle Aged; Nebulizers and Vaporizers; Pyrans; Respiratory Therapy; Rimantadine; Sialic Acids; Zanamivir

2003

Other Studies

37 other study(ies) available for zanamivir and rimantadine

ArticleYear
Synthesis of isoindole and benzoisoindole derivatives of teicoplanin pseudoaglycon with remarkable antibacterial and antiviral activities.
    Bioorganic & medicinal chemistry letters, 2012, Dec-01, Volume: 22, Issue:23

    Topics: Anti-Bacterial Agents; Antiviral Agents; Cell Line; Cell Survival; Drug Resistance, Viral; Gram-Positive Bacteria; Herpesvirus 1, Human; Humans; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H3N2 Subtype; Influenza B virus; Isoindoles; Microbial Sensitivity Tests; o-Phthalaldehyde; Teicoplanin

2012
Microwave assisted synthesis and anti-influenza virus activity of 1-adamantyl substituted N-(1-thia-4-azaspiro[4.5]decan-4-yl)carboxamide derivatives.
    Bioorganic & medicinal chemistry, 2012, Dec-15, Volume: 20, Issue:24

    Topics: Adamantane; Amides; Animals; Antiviral Agents; Aza Compounds; Chickens; Dogs; Humans; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H3N2 Subtype; Influenza B virus; Madin Darby Canine Kidney Cells; Microwaves; Orthomyxoviridae; Spiro Compounds; Structure-Activity Relationship; Virus Replication

2012
Synthesis and Anti-influenza A Virus Activity of 2,2-Dialkylamantadines and Related Compounds.
    ACS medicinal chemistry letters, 2012, Dec-13, Volume: 3, Issue:12

    Topics:

2012
Semisynthetic teicoplanin derivatives as new influenza virus binding inhibitors: synthesis and antiviral studies.
    Bioorganic & medicinal chemistry letters, 2014, Aug-01, Volume: 24, Issue:15

    Topics: Animals; Antiviral Agents; Binding Sites; Dogs; Dose-Response Relationship, Drug; Lipid Bilayers; Madin Darby Canine Kidney Cells; Microbial Sensitivity Tests; Molecular Structure; Orthomyxoviridae; Structure-Activity Relationship; Teicoplanin

2014
Host dihydrofolate reductase (DHFR)-directed cycloguanil analogues endowed with activity against influenza virus and respiratory syncytial virus.
    European journal of medicinal chemistry, 2017, Jul-28, Volume: 135

    Topics: Antiviral Agents; Crystallography, X-Ray; Dose-Response Relationship, Drug; Folic Acid Antagonists; Humans; Influenza A Virus, H1N1 Subtype; Influenza B virus; Microbial Sensitivity Tests; Models, Molecular; Molecular Structure; Proguanil; Respiratory Syncytial Viruses; Structure-Activity Relationship; Tetrahydrofolate Dehydrogenase; Triazines

2017
Synthesis, biological evaluation and molecular modeling of novel azaspiro dihydrotriazines as influenza virus inhibitors targeting the host factor dihydrofolate reductase (DHFR).
    European journal of medicinal chemistry, 2018, Jul-15, Volume: 155

    Topics: Antiviral Agents; Aza Compounds; Dose-Response Relationship, Drug; Folic Acid Antagonists; Models, Molecular; Molecular Structure; Orthomyxoviridae; Spiro Compounds; Structure-Activity Relationship; Tetrahydrofolate Dehydrogenase; Triazines

2018
Structure-activity relationship studies of lipophilic teicoplanin pseudoaglycon derivatives as new anti-influenza virus agents.
    European journal of medicinal chemistry, 2018, Sep-05, Volume: 157

    Topics: Antiviral Agents; Cell Line; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Humans; Influenza A virus; Influenza B virus; Microbial Sensitivity Tests; Molecular Structure; Structure-Activity Relationship; Teicoplanin

2018
Antitumor and antiviral activities of 4-substituted 1,2,3-triazolyl-2,3-dibenzyl-L-ascorbic acid derivatives.
    European journal of medicinal chemistry, 2019, Dec-15, Volume: 184

    Topics: Antineoplastic Agents; Antiviral Agents; Apoptosis; Ascorbic Acid; Cell Proliferation; Cells, Cultured; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Microbial Sensitivity Tests; Molecular Structure; Structure-Activity Relationship; Triazoles; Viruses

2019
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
Anti-influenza virus activity of the neuraminidase inhibitor 4-guanidino-Neu5Ac2en in cell culture and in human respiratory epithelium.
    Antiviral research, 1994, Volume: 25, Issue:2

    Topics: Animals; Antiviral Agents; Cell Line; Dogs; Epithelium; Guanidines; Humans; Influenza A virus; Influenza B virus; Kidney; Neuraminidase; Organ Culture Techniques; Pyrans; Respiratory System; Ribavirin; Rimantadine; Sialic Acids; Virus Replication; Zanamivir

1994
A new antiviral agent for influenza--is there a clinical niche?
    The New England journal of medicine, 1997, Sep-25, Volume: 337, Issue:13

    Topics: Amantadine; Antiviral Agents; Enzyme Inhibitors; Guanidines; Humans; Influenza A virus; Influenza B virus; Influenza, Human; Neuraminidase; Pyrans; Rimantadine; Sialic Acids; Zanamivir

1997
Treating influenza with zanamivir. Management of Influenza in the Southern Hemisphere Trialists.
    Lancet (London, England), 1999, Feb-20, Volume: 353, Issue:9153

    Topics: Administration, Inhalation; Amantadine; Antiviral Agents; Drug Resistance, Microbial; Guanidines; Humans; Influenza, Human; Orthomyxoviridae; Pyrans; Rimantadine; Sialic Acids; Time Factors; Zanamivir

1999
Flu-fighting options: decisions, decisions....
    Health news (Waltham, Mass.), 2000, Volume: 6, Issue:12

    Topics: Acetamides; Amantadine; Antiviral Agents; Guanidines; Humans; Influenza, Human; Oseltamivir; Pneumonia; Pyrans; Rimantadine; Sialic Acids; Zanamivir

2000
ACIP releases guidelines on the prevention and control of influenza. Advisory Committee on Immunization Practices.
    American family physician, 2001, Oct-01, Volume: 64, Issue:7

    Topics: Acetamides; Age Factors; Amantadine; Antiviral Agents; Drug Administration Schedule; Guanidines; Humans; Influenza Vaccines; Influenza, Human; Oseltamivir; Patient Selection; Pyrans; Rimantadine; Sialic Acids; Zanamivir

2001
Prevention and control of influenza. Recommendations of the Advisory Committee on Immunization Practices (ACIP).
    MMWR. Recommendations and reports : Morbidity and mortality weekly report. Recommendations and reports, 2002, Apr-12, Volume: 51, Issue:RR-3

    Topics: Acetamides; Adolescent; Adult; Aged; Amantadine; Antiviral Agents; Child; Child, Preschool; Cost-Benefit Analysis; Guanidines; Humans; Infant; Influenza A virus; Influenza B virus; Influenza Vaccines; Influenza, Human; Middle Aged; Oseltamivir; Pyrans; Rimantadine; Risk Factors; Sialic Acids; United States; Vaccination; Zanamivir

2002
Development of a novel influenza A antiviral assay.
    Journal of virological methods, 2002, Volume: 105, Issue:1

    Topics: Animals; Antiviral Agents; Branched DNA Signal Amplification Assay; Cell Line; Dogs; Guanidines; Humans; Influenza A virus; Influenza, Human; Microbial Sensitivity Tests; Nucleocapsid Proteins; Nucleoproteins; Oligonucleotide Probes; Pyrans; Rimantadine; RNA, Viral; Sialic Acids; Viral Core Proteins; Virus Replication; Zanamivir

2002
Economic analysis of influenza vaccination and antiviral treatment for healthy working adults.
    Annals of internal medicine, 2002, Aug-20, Volume: 137, Issue:4

    Topics: Acetamides; Adolescent; Adult; Antiviral Agents; Computer Simulation; Cost of Illness; Cost-Benefit Analysis; Decision Trees; Drug Costs; Guanidines; Humans; Influenza Vaccines; Influenza, Human; Middle Aged; Oseltamivir; Pyrans; Rimantadine; Sensitivity and Specificity; Sialic Acids; Vaccination; Zanamivir

2002
Summaries for patients. Influenza vaccination or antiviral treatment for healthy working adults: an economic analysis.
    Annals of internal medicine, 2002, Aug-20, Volume: 137, Issue:4

    Topics: Acetamides; Adolescent; Adult; Antiviral Agents; Computer Simulation; Cost of Illness; Cost-Benefit Analysis; Drug Costs; Guanidines; Humans; Influenza Vaccines; Influenza, Human; Middle Aged; Oseltamivir; Pyrans; Rimantadine; Sialic Acids; Vaccination; Zanamivir

2002
Current strategies for management of influenza in the elderly population.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2002, Sep-15, Volume: 35, Issue:6

    Topics: Acetamides; Aged; Aged, 80 and over; Chemoprevention; Complementary Therapies; Cost-Benefit Analysis; Disease Management; Guanidines; Health Services for the Aged; Humans; Influenza, Human; Institutionalization; Oseltamivir; Patient Compliance; Population Surveillance; Prevalence; Pyrans; Rimantadine; Sialic Acids; Vaccination; Zanamivir

2002
Management of influenza in adults older than 65 years of age: cost-effectiveness of rapid testing and antiviral therapy.
    Annals of internal medicine, 2003, Sep-02, Volume: 139, Issue:5 Pt 1

    Topics: Acetamides; Aged; Amantadine; Antiviral Agents; Computer Simulation; Cost-Benefit Analysis; Decision Support Techniques; Guanidines; Humans; Influenza, Human; Oseltamivir; Pyrans; Quality-Adjusted Life Years; Rimantadine; Sensitivity and Specificity; Sialic Acids; Zanamivir

2003
Summaries for patients. Cost-effective management of flu in adults older than 65 years of age.
    Annals of internal medicine, 2003, Sep-02, Volume: 139, Issue:5 Pt 1

    Topics: Acetamides; Aged; Amantadine; Antiviral Agents; Computer Simulation; Cost-Benefit Analysis; Decision Support Techniques; Guanidines; Humans; Influenza, Human; Oseltamivir; Pyrans; Quality-Adjusted Life Years; Rimantadine; Sensitivity and Specificity; Sialic Acids; Zanamivir

2003
[Treatment of influenza in children].
    Zhonghua er ke za zhi = Chinese journal of pediatrics, 2003, Volume: 41, Issue:2

    Topics: Adamantane; Amantadine; Antiviral Agents; Child; Guanidines; Humans; Influenza, Human; Pyrans; Rimantadine; Sialic Acids; Zanamivir

2003
Influenza infection of the embryonated hen's egg/an alternative model for in vivo evaluation of antiviral compounds.
    Arzneimittel-Forschung, 2004, Volume: 54, Issue:2

    Topics: Amantadine; Animals; Antiviral Agents; Chick Embryo; Drug Evaluation, Preclinical; Guanidines; Influenza A virus; Orthomyxoviridae Infections; Pyrans; Rimantadine; Sialic Acids; Survival Analysis; Zanamivir

2004
Avian influenza should be ruffling our feathers.
    The Lancet. Infectious diseases, 2004, Volume: 4, Issue:10

    Topics: Acetamides; Amantadine; Animals; Antiviral Agents; Asia, Eastern; Asia, Southeastern; Birds; Disease Outbreaks; Guanidines; Humans; Influenza in Birds; Influenza Vaccines; Influenza, Human; International Cooperation; Neuraminidase; Oseltamivir; Pyrans; Rimantadine; Sialic Acids; World Health Organization; Zanamivir

2004
Neuraminidase inhibitor-rimantadine combinations exert additive and synergistic anti-influenza virus effects in MDCK cells.
    Antimicrobial agents and chemotherapy, 2004, Volume: 48, Issue:12

    Topics: Acetamides; Animals; Antiviral Agents; Cell Line; Cell Survival; Dogs; Drug Synergism; Enzyme Inhibitors; Guanidines; Influenza A virus; Neuraminidase; Oseltamivir; Pyrans; Rimantadine; Sialic Acids; Viral Plaque Assay; Virus Replication; Zanamivir

2004
Utilization of the embryonated egg for in vivo evaluation of the anti-influenza virus activity of neuraminidase inhibitors.
    Medical microbiology and immunology, 2006, Volume: 195, Issue:2

    Topics: Acetamides; Amantadine; Animals; Antiviral Agents; Chick Embryo; Chickens; Enzyme Inhibitors; Guanidines; Influenza A virus; Influenza in Birds; Microbial Sensitivity Tests; Neuraminidase; Oseltamivir; Pyrans; Rimantadine; Sialic Acids; Zanamivir

2006
Increased adamantane resistance in influenza A(H3) viruses in Australia and neighbouring countries in 2005.
    Antiviral research, 2007, Volume: 73, Issue:2

    Topics: Adamantane; Antiviral Agents; Australia; Drug Resistance, Viral; Hemagglutinin Glycoproteins, Influenza Virus; Humans; Influenza A virus; Influenza, Human; Mutation; Neuraminidase; Oseltamivir; Phylogeny; Rimantadine; Zanamivir

2007
Antiviral management of seasonal and pandemic influenza.
    The Journal of infectious diseases, 2006, Nov-01, Volume: 194 Suppl 2

    Topics: Amantadine; Animals; Antiviral Agents; Clinical Trials as Topic; Disease Outbreaks; Drug Resistance, Viral; Enzyme Inhibitors; Humans; Influenza A Virus, H3N2 Subtype; Influenza A Virus, H5N1 Subtype; Influenza, Human; Mice; Neuraminidase; Oseltamivir; Rimantadine; Seasons; Zanamivir

2006
[Significance of virological diagnostics for the effective treatment of hospitalized patients infected with influenza virus].
    Pneumonologia i alergologia polska, 2006, Volume: 74, Issue:2

    Topics: Adult; Amantadine; Antiviral Agents; Diagnosis, Differential; Fluorescent Antibody Technique; Hospitalization; Humans; Influenza A virus; Influenza, Human; Middle Aged; Oseltamivir; Respiratory Tract Diseases; Reverse Transcriptase Polymerase Chain Reaction; Rimantadine; Treatment Outcome; Zanamivir

2006
Drug-induced linear immunoglobulin A bullous dermatosis mimicking Stevens-Johnson syndrome: a case report.
    Cutis, 2007, Volume: 79, Issue:3

    Topics: Anti-Infective Agents; Autoimmune Diseases; Azithromycin; Diagnosis, Differential; Drug Eruptions; Fluorescent Antibody Technique, Direct; Humans; Immunoglobulin A; Male; Middle Aged; Rimantadine; Skin; Skin Diseases, Vesiculobullous; Stevens-Johnson Syndrome; Zanamivir

2007
Influenza.
    Canadian family physician Medecin de famille canadien, 2008, Volume: 54, Issue:3

    Topics: Amantadine; Antiviral Agents; Humans; Influenza Vaccines; Influenza, Human; Mass Vaccination; Oseltamivir; Rimantadine; Zanamivir

2008
Antivirals and influenza: frequency of resistance.
    The Pediatric infectious disease journal, 2008, Volume: 27, Issue:10 Suppl

    Topics: Amantadine; Antiviral Agents; Disease Outbreaks; Drug Resistance, Viral; Humans; Influenza A virus; Influenza A Virus, H5N1 Subtype; Influenza B virus; Influenza, Human; Neuraminidase; Oseltamivir; Rimantadine; Zanamivir

2008
Detection of molecular markers of antiviral resistance in influenza A (H5N1) viruses using a pyrosequencing method.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:3

    Topics: Amantadine; Animals; Antiviral Agents; Birds; Drug Resistance, Viral; Genetic Markers; Humans; Influenza A Virus, H5N1 Subtype; Influenza in Birds; Influenza, Human; Neuraminidase; Oseltamivir; Reverse Transcriptase Polymerase Chain Reaction; Rimantadine; RNA, Viral; Sensitivity and Specificity; Sequence Analysis, RNA; Zanamivir

2009
Oseltamivir resistance and the H274Y neuraminidase mutation in seasonal, pandemic and highly pathogenic influenza viruses.
    Drugs, 2009, Volume: 69, Issue:18

    Topics: Cross Infection; Drug Resistance, Viral; Global Health; Humans; Influenza A virus; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H5N1 Subtype; Influenza B virus; Influenza Vaccines; Influenza, Human; Mutation; Neuraminidase; Oseltamivir; Population Surveillance; Rimantadine; Zanamivir

2009
Influenza antiviral prescribing practices during the 2007-08 and 2008-09 influenza seasons in the setting of increased resistance to oseltamivir among circulating influenza viruses.
    Antiviral research, 2010, Volume: 88, Issue:2

    Topics: Adamantane; Antiviral Agents; Disease Outbreaks; Drug Resistance, Viral; Drug Utilization; Humans; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H3N2 Subtype; Influenza, Human; Oseltamivir; Practice Guidelines as Topic; Practice Patterns, Physicians'; Retrospective Studies; Rimantadine; Seasons; Surveys and Questionnaires; Zanamivir

2010
Description of antiviral treatment among adults hospitalized with influenza before and during the 2009 pandemic: United States, 2005-2009.
    The Journal of infectious diseases, 2011, Dec-15, Volume: 204, Issue:12

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amantadine; Antiviral Agents; Drug Therapy, Combination; Female; Guideline Adherence; Hospitalization; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Male; Middle Aged; Odds Ratio; Oseltamivir; Pandemics; Practice Guidelines as Topic; Practice Patterns, Physicians'; Pregnancy; Pregnancy Complications, Infectious; Rimantadine; United States; Young Adult; Zanamivir

2011
Site-directed M2 proton channel inhibitors enable synergistic combination therapy for rimantadine-resistant pandemic influenza.
    PLoS pathogens, 2020, Volume: 16, Issue:8

    Topics: Antiviral Agents; Drug Resistance, Viral; Drug Synergism; Drug Therapy, Combination; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Rimantadine; Viral Matrix Proteins; Zanamivir

2020