zanamivir has been researched along with 4-amino-2-deoxy-2,3-didehydro-n-acetylneuraminic acid in 10 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (50.00) | 18.2507 |
| 2000's | 2 (20.00) | 29.6817 |
| 2010's | 3 (30.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bethell, R; Cherry, PC; Cleasby, A; Colman, P; Howes, PD; Singh, O; Skarzynski, T; Smith, PW; Sollis, SL; Taylor, NR; Varghese, J; Wonacott, AJ | 1 |
| Blick, TJ; Colman, PM; McKimm-Breschkin, JL; Sahasrabudhe, A; Smith, PW; Sollis, SL; Varghese, JN | 1 |
| Chen, XG; Chen, YL; Hu, ZD; Liu, MC; Lü, WJ; Luan, F; Ma, WP; Zhang, XY | 1 |
| Cheng, YS; Fang, JM; Tsai, KC; Wang, SY; Wen, WH; Wong, CH; Yang, AS | 1 |
| Boulanger, MJ; Brant, MG; Bromba, CM; Chan, T; Lunke, MD; Mason, JW; Petric, M; Wulff, JE | 1 |
| Bhatt, B; Böhm, R; Dyason, JC; Kerry, PS; Russell, RJ; Thomson, RJ; von Itzstein, M | 1 |
| Dyason, JC; Jin, B; Kok, GB; Oliver, SW; Pegg, MS; Smythe, ML; Van Phan, T; von Itzstein, M; White, HF; Wu, WY | 1 |
| Bethell, RC; Blick, TJ; Hart, GJ; Marshall, D; McKimm-Breschkin, JL; Penn, CR; Sahasrabudhe, A; Tiong, T | 1 |
| Bethell, RC; Blick, TJ; Colman, PM; Hart, GJ; McDonald, M; McKimm-Breschkin, JL; Sahasrabudhe, A; Varghese, JN | 1 |
| Johnson, MA; McKimm-Breschkin, JL; Selleck, PW; Usman, TB | 1 |
10 other study(ies) available for zanamivir and 4-amino-2-deoxy-2,3-didehydro-n-acetylneuraminic acid
| Article | Year |
|---|---|
Dihydropyrancarboxamides related to zanamivir: a new series of inhibitors of influenza virus sialidases. 2. Crystallographic and molecular modeling study of complexes of 4-amino-4H-pyran-6-carboxamides and sialidase from influenza virus types A and B.
Topics: Acetamides; Antiviral Agents; Binding Sites; Crystallography, X-Ray; Enzyme Inhibitors; Guanidines; Influenza A virus; Influenza B virus; Models, Molecular; Neuraminidase; Protein Conformation; Pyrans; Sialic Acids; Zanamivir | 1998 |
Drug design against a shifting target: a structural basis for resistance to inhibitors in a variant of influenza virus neuraminidase.
Topics: Antiviral Agents; Arginine; Drug Design; Drug Resistance, Microbial; Influenza A virus; Mutation; Neuraminidase | 1998 |
QSAR study of neuraminidase inhibitors based on heuristic method and radial basis function network.
Topics: Enzyme Inhibitors; Linear Models; Models, Biological; Neuraminidase; Quantitative Structure-Activity Relationship | 2008 |
Analogs of zanamivir with modified C4-substituents as the inhibitors against the group-1 neuraminidases of influenza viruses.
Topics: Antiviral Agents; Enzyme Inhibitors; Influenza A Virus, H1N1 Subtype; Inhibitory Concentration 50; Neuraminidase; Orthomyxoviridae; Protein Binding; Protein Conformation; Structure-Activity Relationship; Zanamivir | 2010 |
The de-guanidinylated derivative of peramivir remains a potent inhibitor of influenza neuraminidase.
Topics: Acids, Carbocyclic; Antiviral Agents; Crystallography, X-Ray; Cyclopentanes; Dose-Response Relationship, Drug; Drug Design; Enzyme Inhibitors; Guanidines; Humans; Influenza A virus; Inhibitory Concentration 50; Models, Molecular; Molecular Structure; Neuraminidase; Protein Binding; Recombinant Proteins; Zanamivir | 2011 |
Exploring the interactions of unsaturated glucuronides with influenza virus sialidase.
Topics: Acetamides; Antiviral Agents; Catalytic Domain; Enzyme Assays; Fluorometry; Glucuronides; Hydrophobic and Hydrophilic Interactions; Models, Molecular; Neuraminidase; Orthomyxoviridae; Static Electricity; Structure-Activity Relationship | 2012 |
Rational design of potent sialidase-based inhibitors of influenza virus replication.
Topics: Animals; Antiviral Agents; Cell Line; Computer-Aided Design; Disease Models, Animal; Drug Design; Female; Ferrets; Guanidines; Humans; Influenza A virus; Influenza, Human; Mice; Models, Molecular; Neuraminidase; Pyrans; Sheep; Sialic Acids; Viral Plaque Assay; Virus Replication; Zanamivir | 1993 |
Generation and characterization of variants of NWS/G70C influenza virus after in vitro passage in 4-amino-Neu5Ac2en and 4-guanidino-Neu5Ac2en.
Topics: Antiviral Agents; Drug Resistance, Microbial; Drug Stability; Guanidines; Hemagglutination Tests; Hemagglutinins; Influenza A virus; Kinetics; Neuraminidase; Pyrans; Sequence Analysis, DNA; Sialic Acids; Viral Plaque Assay; Virus Replication; Zanamivir | 1996 |
Mutations in a conserved residue in the influenza virus neuraminidase active site decreases sensitivity to Neu5Ac2en-derived inhibitors.
Topics: Acetamides; Adsorption; Animals; Binding Sites; Birds; Cell Line; Conserved Sequence; Dogs; Drug Resistance, Microbial; Enzyme Inhibitors; Guanidines; Heating; Hemagglutinin Glycoproteins, Influenza Virus; Humans; Influenza A virus; Kinetics; Molecular Structure; Mutation; N-Acetylneuraminic Acid; Neuraminidase; Oseltamivir; Phenotype; Pyrans; Sialic Acids; Substrate Specificity; Viral Plaque Assay; Virus Replication; Zanamivir | 1998 |
Reduced sensitivity of influenza A (H5N1) to oseltamivir.
Topics: Antiviral Agents; Drug Resistance, Viral; Influenza A Virus, H5N1 Subtype; Oseltamivir; Sialic Acids; Zanamivir | 2007 |