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zalospirone and 8-hydroxy-2-(di-n-propylamino)tetralin

zalospirone has been researched along with 8-hydroxy-2-(di-n-propylamino)tetralin in 2 studies

*8-Hydroxy-2-(di-n-propylamino)tetralin: A serotonin 1A-receptor agonist that is used experimentally to test the effects of serotonin. [MeSH]

Compound Research Comparison

Studies (zalospirone)	Trials (zalospirone)	Recent Studies (post-2010) (zalospirone)	Studies (8-hydroxy-2-(di-n-propylamino)tetralin)	Trials (8-hydroxy-2-(di-n-propylamino)tetralin)	Recent Studies (post-2010) (8-hydroxy-2-(di-n-propylamino)tetralin)
5	1	0	3,530	7	389

Protein Interaction Comparison

Protein	Taxonomy	8-hydroxy-2-(di-n-propylamino)tetralin (IC50)
5-hydroxytryptamine receptor 1A	Homo sapiens (human)	0.0012
5-hydroxytryptamine receptor 1A	Rattus norvegicus (Norway rat)	0.0032
Alpha-2B adrenergic receptor	Rattus norvegicus (Norway rat)	0.81
D(2) dopamine receptor	Bos taurus (cattle)	0.8
Alpha-2C adrenergic receptor	Rattus norvegicus (Norway rat)	0.81
Alpha-2A adrenergic receptor	Rattus norvegicus (Norway rat)	0.81
D(2) dopamine receptor	Rattus norvegicus (Norway rat)	2.8959
Lysosomal alpha-glucosidase	Bos taurus (cattle)	0.0021

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	2 (100.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Audinot, V; Chaput, C; Conte, C; Gavaudan, S; Millan, MJ; Newman-Tancredi, A; Touzard, M; Verrièle, L	1
Lucki, I; Singh, A	1

Other Studies

2 other study(ies) available for zalospirone and 8-hydroxy-2-(di-n-propylamino)tetralin

Article	Year
Agonist and antagonist actions of antipsychotic agents at 5-HT1A receptors: a [35S]GTPgammaS binding study. European journal of pharmacology, 1998, Aug-21, Volume: 355, Issue:2-3 Topics: Animals; Antipsychotic Agents; CHO Cells; Cricetinae; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Agents; Sulfur Radioisotopes	1998
Antidepressant-like activity of compounds with varying efficacy at 5-HT1A receptors. Neuropharmacology, 1993, Volume: 32, Issue:4 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antidepressive Agents; Behavior, Animal; Dose-Response Relationship, Drug; Isoindoles; Male; Motor Activity; Piperazines; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin Antagonists; Swimming	1993

Article

Year

Agonist and antagonist actions of antipsychotic agents at 5-HT1A receptors: a [35S]GTPgammaS binding study.

European journal of pharmacology, 1998, Aug-21, Volume: 355, Issue:2-3

Topics: Animals; Antipsychotic Agents; CHO Cells; Cricetinae; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Agents; Sulfur Radioisotopes

1998

Antidepressant-like activity of compounds with varying efficacy at 5-HT1A receptors.

Neuropharmacology, 1993, Volume: 32, Issue:4

Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antidepressive Agents; Behavior, Animal; Dose-Response Relationship, Drug; Isoindoles; Male; Motor Activity; Piperazines; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin Antagonists; Swimming

1993