Page last updated: 2024-08-16

zaleplon and zopiclone

zaleplon has been researched along with zopiclone in 68 studies

Research

Studies (68)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	3 (4.41)	18.2507
2000's	36 (52.94)	29.6817
2010's	26 (38.24)	24.3611
2020's	3 (4.41)	2.80

Authors

Authors	Studies
Lombardo, F; Obach, RS; Waters, NJ	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Hening, WA; Wagner, J; Wagner, ML	1
Sanger, DJ	2
Griebel, G; Perrault, G; Sanger, DJ	1
Lang, KM; Levy, E; Levy, P; Menzin, J	1
Darwish, M; Patat, A; Paty, I; Riedel, WJ; van Boxtel, MP; Vermeeren, A	1
Fortin, M; Hawa, R; Matte, J; Moller, H; Montplaisir, J; Morin, C; Reinish, L; Shapiro, CM	1
Palomba, V; Parrino, L; Rossi, M; Smerieri, A; Terzano, MG	1
Haga, C	1
Greenblatt, DJ; Hesse, LM; von Moltke, LL	1
Wiegand, MH	1
Kitazumi, K; Mori, M; Noguchi, H; Shiba, T; Shiobara, Y	1
Gray, G; Kenny, G; Paul, MA; Pigeau, RA	1
Drover, DR	1
Kitazumi, K; Mori, M; Noguchi, H; Shiba, T	1
Gray, G; MacLellan, M; Paul, MA; Pigeau, RA	1
Boland, A; Dickson, R; Dodd, S; Dündar, Y; Strobl, J; Walley, T	1
Nutt, DJ	1
Alford, C; Verster, J	1
Anderson, I	1
Baldwin, D	1
Lader, M	1
Akwa, Y; Allain, H; Bentué-Ferrer, D; Patat, A; Polard, E	1
Neubauer, D	1
Ariniemi, K; Gunnar, T; Lillsunde, P	1
Gammack, JK; Kamel, NS	1
Antai-Otong, D	1
Carter, B; Kassam, A; Patten, SB	1
Bramness, JG; Mellingsaeter, TC; Slørdal, L	1
Collier, S; Gibson, S; Latham, M; Qureshi, Z; Siriwardena, AN	1
Capua, T; Shapiro, CM	1
Cranwell-Bruce, LA	1
Belleville, G; Morin, CM	1
Dyas, JV; Middleton, H; Orner, R; Qureshi, MZ; Siriwardena, AN	1
Barhate, R; Catbagan, P; Coulter, C; Huynh, K; Moore, C; Rodrigues, W; Soares, J; Wang, G	1
Mets, MA; Olivier, B; Verster, JC; Volkerts, ER	1
Andersen, AB; Frydenberg, M	1
Källén, B; Wikner, BN	1
Maurer, HH; Meyer, MR; Remane, D; Wissenbach, DK	1
Gregory, P; Kucharczyk, E; Morgan, K	1
Bonato, PS; Tonon, MA	1
Roth, T; Verster, JC	1
Gunja, N	2
Nguyen, JM; Pivette, J; Rat, C; Senand, R; Werner, EL	1
Bervoets, AC; de Klerk, S; Roth, T; Verster, JC	1
Ewald, AH; Hopf, M; Maurer, HH; Montenarh, D; Schmidt, P	1
Karlonas, N; Ramanaviciene, A; Ramanavicius, A	1
Crowe, SF; Stranks, EK	1
Dargan, PI; Green, JL; Kapil, V; Le Lait, C; Wood, DM	1
Bai, YM; Chen, MH; Chen, TJ; Chou, YH; Liou, YJ; Su, TP; Wei, HT; Wong, WW	1
Bergman, JC; Gardner, DM; Murphy, AL; Pollmann, AS	1
He, HY; Lian, J; She, CM; Zhang, YZ	1
Benegal, V; Bokka, S; Chand, P; Kandasamy, A; Murthy, P; Shukla, L; Shukla, T	1
Asaly, A; Kolenberg Geron, L; Matok, I; Perlman, A; Treves, N	1
Chiappini, S; Corkery, JM; Guirguis, A; Schifano, F	1
Alessi-Severini, S; Brandt, J; Leong, C; Singer, A	1
Nordström, A; Nordström, P	1
Annand, F; Burkinshaw, P; Carville, S; Eastwood, B; Greaves, F; Kelleher, M; Knight, J; Marsden, J; O'Connor, R; Taylor, S; Tran, A; White, M; Willey, P	1
Aldus, C; Arthur, A; Ballard, C; Boyd, PJ; Fox, C; Howard, R; Loke, YK; Maidment, I; Richardson, K; Savva, GM; Steel, N	1
Bateman, BT; Huybrechts, KF; Levin, R; Szmulewicz, A	1
Astashkina, OG; Kalyokin, RA; Orlova, AM; Pavlova, AZ; Volkova, AA	1

Reviews

21 review(s) available for zaleplon and zopiclone

Article	Year
Beyond benzodiazepines: alternative pharmacologic agents for the treatment of insomnia. The Annals of pharmacotherapy, 1998, Volume: 32, Issue:6 Topics: Acetamides; Azabicyclo Compounds; Benzodiazepines; Clinical Protocols; Humans; Hypnotics and Sedatives; Melatonin; Phytotherapy; Piperazines; Plants, Medicinal; Pyridines; Pyrimidines; Receptors, GABA-A; Sleep; Sleep Initiation and Maintenance Disorders; Valerian; Zolpidem	1998
Zopiclone and zaleplon vs benzodiazepines in the treatment of insomnia: Canadian consensus statement. Human psychopharmacology, 2003, Volume: 18, Issue:1 Topics: Acetamides; Anti-Anxiety Agents; Azabicyclo Compounds; Benzodiazepines; Canada; Consensus; Drug Interactions; Drug Utilization Review; Humans; Hypnotics and Sedatives; Piperazines; Pyrimidines; Sleep Initiation and Maintenance Disorders	2003
New drugs for insomnia: comparative tolerability of zopiclone, zolpidem and zaleplon. Drug safety, 2003, Volume: 26, Issue:4 Topics: Acetamides; Animals; Azabicyclo Compounds; Clinical Trials as Topic; Humans; Piperazines; Pyridines; Pyrimidines; Sleep Initiation and Maintenance Disorders; Zolpidem	2003
Clinically important drug interactions with zopiclone, zolpidem and zaleplon. CNS drugs, 2003, Volume: 17, Issue:7 Topics: Acetamides; Antidepressive Agents; Antipsychotic Agents; Azabicyclo Compounds; Drug Interactions; Histamine Antagonists; Humans; Hypnotics and Sedatives; Pharmaceutical Preparations; Piperazines; Pyridines; Pyrimidines; Sleep Initiation and Maintenance Disorders; Zolpidem	2003
[Drug treatment of sleep disorders in the elderly]. Der Internist, 2003, Volume: 44, Issue:9 Topics: Acetamides; Aged; Aged, 80 and over; Antidepressive Agents; Antipsychotic Agents; Azabicyclo Compounds; Benzodiazepines; Chronotherapy; Combined Modality Therapy; Humans; Hypnotics and Sedatives; Phytotherapy; Piperazines; Practice Patterns, Physicians'; Pyridines; Pyrimidines; Sleep Initiation and Maintenance Disorders; Sleep Wake Disorders; Zolpidem	2003
Comparative pharmacokinetics and pharmacodynamics of short-acting hypnosedatives: zaleplon, zolpidem and zopiclone. Clinical pharmacokinetics, 2004, Volume: 43, Issue:4 Topics: Acetamides; Aged; Azabicyclo Compounds; Humans; Hypnotics and Sedatives; Liver Failure; Piperazines; Pyridines; Pyrimidines; Renal Insufficiency; Zolpidem	2004
Comparative efficacy of newer hypnotic drugs for the short-term management of insomnia: a systematic review and meta-analysis. Human psychopharmacology, 2004, Volume: 19, Issue:5 Topics: Acetamides; Azabicyclo Compounds; Benzodiazepines; Humans; Hypnotics and Sedatives; Piperazines; Pyridines; Pyrimidines; Randomized Controlled Trials as Topic; Sleep Initiation and Maintenance Disorders; Zolpidem	2004
The pharmacology and mechanisms of action of new generation, non-benzodiazepine hypnotic agents. CNS drugs, 2004, Volume: 18 Suppl 1 Topics: Acetamides; Animals; Azabicyclo Compounds; GABA-A Receptor Agonists; Humans; Hypnotics and Sedatives; Piperazines; Pyridines; Pyrimidines; Sleep Initiation and Maintenance Disorders; Zolpidem	2004
Postural instability and consequent falls and hip fractures associated with use of hypnotics in the elderly: a comparative review. Drugs & aging, 2005, Volume: 22, Issue:9 Topics: Accidental Falls; Acetamides; Aged; Aged, 80 and over; Azabicyclo Compounds; Benzodiazepines; Case-Control Studies; Hip Fractures; Humans; Hypnotics and Sedatives; Pharmacoepidemiology; Piperazines; Postural Balance; Posture; Prospective Studies; Pyridines; Pyrimidines; Retrospective Studies; Risk Assessment; Sleep Initiation and Maintenance Disorders; Zolpidem	2005
Insomnia in the elderly: cause, approach, and treatment. The American journal of medicine, 2006, Volume: 119, Issue:6 Topics: Acetamides; Aged; Aging; Antidepressive Agents; Azabicyclo Compounds; Behavior Therapy; Benzodiazepines; Humans; Hypnotics and Sedatives; Nonprescription Drugs; Piperazines; Pyridines; Pyrimidines; Receptor, Melatonin, MT1; Receptor, Melatonin, MT2; Sleep; Sleep Initiation and Maintenance Disorders; Sleep, REM; Thiophenes; Trazodone; Zolpidem	2006
The art of prescribing. Risks and benefits of non-benzodiazepine receptor agonists in the treatment of acute primary insomnia in older adults. Perspectives in psychiatric care, 2006, Volume: 42, Issue:3 Topics: Acetamides; Acute Disease; Azabicyclo Compounds; Benzodiazepines; Causality; Drug Prescriptions; GABA Agonists; Humans; Hypnotics and Sedatives; Nursing Assessment; Patient Selection; Piperazines; Prevalence; Professional Autonomy; Psychiatric Nursing; Pyridines; Pyrimidines; Sleep Initiation and Maintenance Disorders; Zolpidem	2006
Hypnotic sedative drugs. Medsurg nursing : official journal of the Academy of Medical-Surgical Nurses, 2007, Volume: 16, Issue:3 Topics: Acetamides; Azabicyclo Compounds; Chemistry, Pharmaceutical; Cost of Illness; Humans; Hypnotics and Sedatives; Indenes; Nurse's Role; Patient Education as Topic; Piperazines; Pyridines; Pyrimidines; Sleep Initiation and Maintenance Disorders; Zolpidem	2007
Methods for the analysis of nonbenzodiazepine hypnotic drugs in biological matrices. Bioanalysis, 2012, Volume: 4, Issue:3 Topics: Acetamides; Azabicyclo Compounds; Chromatography, High Pressure Liquid; Electrophoresis, Capillary; Humans; Hypnotics and Sedatives; Mass Spectrometry; Piperazines; Pyridines; Pyrimidines; Sleep Initiation and Maintenance Disorders; Zolpidem	2012
Gender differences in highway driving performance after administration of sleep medication: a review of the literature. Traffic injury prevention, 2012, Volume: 13, Issue:3 Topics: Acetamides; Automobile Driving; Azabicyclo Compounds; Environment Design; Female; Flurazepam; Humans; Hypnotics and Sedatives; Indenes; Lorazepam; Male; Piperazines; Psychomotor Performance; Pyridines; Pyrimidines; Sex Factors; Sleep Wake Disorders; Zolpidem	2012
The clinical and forensic toxicology of Z-drugs. Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2013, Volume: 9, Issue:2 Topics: Acetamides; Azabicyclo Compounds; Coma; Drug Overdose; Flumazenil; GABA Modulators; GABA-A Receptor Agonists; Humans; Hypnotics and Sedatives; Piperazines; Pyridines; Pyrimidines; Zolpidem	2013
In the Zzz zone: the effects of Z-drugs on human performance and driving. Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2013, Volume: 9, Issue:2 Topics: Acetamides; Automobile Driving; Azabicyclo Compounds; GABA-A Receptor Agonists; Humans; Hypnotics and Sedatives; Piperazines; Psychomotor Disorders; Psychomotor Performance; Pyridines; Pyrimidines; Zolpidem	2013
The acute cognitive effects of zopiclone, zolpidem, zaleplon, and eszopiclone: a systematic review and meta-analysis. Journal of clinical and experimental neuropsychology, 2014, Volume: 36, Issue:7 Topics: Acetamides; Attention; Azabicyclo Compounds; Eszopiclone; Humans; Hypnotics and Sedatives; Memory; Piperazines; Psychomotor Performance; Pyridines; Pyrimidines; Zolpidem	2014
Deprescribing benzodiazepines and Z-drugs in community-dwelling adults: a scoping review. BMC pharmacology & toxicology, 2015, Jul-04, Volume: 16 Topics: Acetamides; Azabicyclo Compounds; Benzodiazepines; Deprescriptions; Humans; Piperazines; Pyridines; Pyrimidines; Zolpidem	2015
[Research Progress on Forensic Toxicology of Z-drugs]. Fa yi xue za zhi, 2015, Volume: 31, Issue:4 Topics: Acetamides; Azabicyclo Compounds; Drug Overdose; Forensic Medicine; Forensic Toxicology; Humans; Hypnotics and Sedatives; Piperazines; Pyridines; Pyrimidines; Sleep Initiation and Maintenance Disorders; Zolpidem	2015
Z-drugs and risk for falls and fractures in older adults-a systematic review and meta-analysis. Age and ageing, 2018, 03-01, Volume: 47, Issue:2 Topics: Accidental Falls; Acetamides; Adult; Age Factors; Aged; Aged, 80 and over; Aging; Azabicyclo Compounds; Eszopiclone; Fractures, Bone; Humans; Middle Aged; Piperazines; Pyrimidines; Risk Assessment; Risk Factors; Sleep; Sleep Aids, Pharmaceutical; Sleep Initiation and Maintenance Disorders; Zolpidem	2018
Medicines associated with dependence or withdrawal: a mixed-methods public health review and national database study in England. The lancet. Psychiatry, 2019, Volume: 6, Issue:11 Topics: Acetamides; Adolescent; Adult; Aged; Analgesics; Analgesics, Opioid; Antidepressive Agents; Azabicyclo Compounds; Benzodiazepines; Databases, Factual; England; Female; Gabapentin; Humans; Hypnotics and Sedatives; Male; Middle Aged; Piperazines; Pregabalin; Public Health; Pyrimidines; Substance Withdrawal Syndrome; Substance-Related Disorders; Young Adult; Zolpidem	2019

Trials

4 trial(s) available for zaleplon and zopiclone

Article	Year
Differential residual effects of zaleplon and zopiclone on actual driving: a comparison with a low dose of alcohol. Sleep, 2002, Mar-15, Volume: 25, Issue:2 Topics: Acetamides; Adult; Automobile Driving; Azabicyclo Compounds; Cross-Over Studies; Disorders of Excessive Somnolence; Double-Blind Method; Drug Administration Schedule; Ethanol; Female; Humans; Hypnotics and Sedatives; Male; Piperazines; Psychomotor Disorders; Pyrimidines; Single-Blind Method	2002
Impact of melatonin, zaleplon, zopiclone, and temazepam on psychomotor performance. Aviation, space, and environmental medicine, 2003, Volume: 74, Issue:12 Topics: Acetamides; Administration, Oral; Adult; Anti-Anxiety Agents; Antioxidants; Azabicyclo Compounds; Cross-Over Studies; Double-Blind Method; Fatigue; Female; Half-Life; Humans; Hypnotics and Sedatives; Male; Melatonin; Middle Aged; Military Personnel; Piperazines; Placebos; Psychomotor Performance; Pyrimidines; Sleep; Task Performance and Analysis; Temazepam	2003
Sleep-inducing pharmaceuticals: a comparison of melatonin, zaleplon, zopiclone, and temazepam. Aviation, space, and environmental medicine, 2004, Volume: 75, Issue:6 Topics: Acetamides; Adult; Anticonvulsants; Azabicyclo Compounds; Cross-Over Studies; Double-Blind Method; Electroencephalography; Female; Humans; Hypnotics and Sedatives; Male; Melatonin; Middle Aged; Piperazines; Psychomotor Performance; Pyrimidines; Sleep; Temazepam	2004
Hypnotic discontinuation in chronic insomnia: impact of psychological distress, readiness to change, and self-efficacy. Health psychology : official journal of the Division of Health Psychology, American Psychological Association, 2008, Volume: 27, Issue:2 Topics: Acetamides; Adaptation, Psychological; Adult; Aged; Anxiety; Attitude to Health; Azabicyclo Compounds; Benzodiazepines; Chronic Disease; Cognitive Behavioral Therapy; Combined Modality Therapy; Depression; Female; Follow-Up Studies; Humans; Hypnotics and Sedatives; Individuality; Male; Middle Aged; Motivation; Patient Compliance; Personality Inventory; Piperazines; Pyrimidines; Self Care; Self Efficacy; Sleep Initiation and Maintenance Disorders; Stress, Psychological; Substance Withdrawal Syndrome	2008

Other Studies

43 other study(ies) available for zaleplon and zopiclone

Article	Year
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
The effects of new hypnotic drugs in rats trained to discriminate ethanol. Behavioural pharmacology, 1997, Volume: 8, Issue:4 Topics: Acetamides; Animals; Anti-Anxiety Agents; Azabicyclo Compounds; Barbiturates; Benzodiazepines; Central Nervous System Depressants; Discrimination, Psychological; Dose-Response Relationship, Drug; Drugs, Investigational; Ethanol; Hypnotics and Sedatives; Male; Naphthyridines; Piperazines; Pyridines; Pyrimidines; Rats; Rats, Wistar; Zolpidem	1997
Limited anxiolytic-like effects of non-benzodiazepine hypnotics in rodents. Journal of psychopharmacology (Oxford, England), 1998, Volume: 12, Issue:4 Topics: Acetamides; Animals; Anti-Anxiety Agents; Avoidance Learning; Azabicyclo Compounds; Benzodiazepines; Escape Reaction; Hypnotics and Sedatives; Male; Maze Learning; Motor Activity; Piperazines; Punishment; Pyridines; Pyrimidines; Rats; Rats, Wistar; Triazolam; Zolpidem	1998
A general model of the effects of sleep medications on the risk and cost of motor vehicle accidents and its application to France. PharmacoEconomics, 2001, Volume: 19, Issue:1 Topics: Accidents, Traffic; Acetamides; Azabicyclo Compounds; France; Humans; Hypnotics and Sedatives; Models, Economic; Piperazines; Psychomotor Performance; Pyrimidines; Randomized Controlled Trials as Topic; Sleep	2001
[Poisonings with benzodiazepine-like drugs]. Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 2003, Feb-20, Volume: 123, Issue:4 Topics: Acetamides; Antidotes; Azabicyclo Compounds; Flumazenil; Humans; Hypnotics and Sedatives; Norway; Piperazines; Poisoning; Pyridines; Pyrimidines; Zolpidem	2003
Effect of zaleplon, a non-benzodiazepine hypnotic, on melatonin secretion in rabbits. Journal of pharmacological sciences, 2003, Volume: 93, Issue:2 Topics: Acetamides; Animals; Azabicyclo Compounds; Cells, Cultured; Cyclic AMP; Dose-Response Relationship, Drug; Electroencephalography; Hypnotics and Sedatives; Male; Melatonin; Pineal Gland; Piperazines; Pyrimidines; Rabbits; Rats; Rats, Sprague-Dawley; Triazolam	2003
Electroencephalographic properties of zaleplon, a non-benzodiazepine sedative/hypnotic, in rats. Journal of pharmacological sciences, 2004, Volume: 94, Issue:3 Topics: Acetamides; Administration, Oral; Animals; Azabicyclo Compounds; Cerebral Cortex; Dose-Response Relationship, Drug; Electrodes, Implanted; Electroencephalography; Hypnotics and Sedatives; Male; Nitrazepam; Piperazines; Pyrimidines; Rats; Rats, Sprague-Dawley; Sleep Initiation and Maintenance Disorders; Sleep Stages; Triazolam; Upper Extremity	2004
Sleeping pills without regrets. They've long been the risky quick fixes of sleep medicine. Soon some sleeping pills may be sold as long-term solutions. Harvard health letter, 2004, Volume: 29, Issue:10 Topics: Acetamides; Age Factors; Azabicyclo Compounds; Benzodiazepines; Humans; Hypnotics and Sedatives; Piperazines; Pyridines; Pyrimidines; Sleep Wake Disorders; Thiophenes; Trazodone; Zolpidem	2004
NICE: The National Institute of Clinical Excellence -- or Eccentricity? Reflections on the Z-drugs as hypnotics. Journal of psychopharmacology (Oxford, England), 2005, Volume: 19, Issue:2 Topics: Acetamides; Azabicyclo Compounds; Benzodiazepines; Half-Life; Humans; Hypnotics and Sedatives; Piperazines; Pyridines; Pyrimidines; Sleep Initiation and Maintenance Disorders; Substance-Related Disorders; Zolpidem	2005
NICE review: not nice for patients! Journal of psychopharmacology (Oxford, England), 2005, Volume: 19, Issue:2 Topics: Acetamides; Azabicyclo Compounds; Benzodiazepines; Half-Life; Humans; Hypnotics and Sedatives; Piperazines; Pyridines; Pyrimidines; Sleep Initiation and Maintenance Disorders; Substance-Related Disorders; Zolpidem	2005
Making decisions in the absence of high quality clinical evidence: we need to bring some science into the judgement. Journal of psychopharmacology (Oxford, England), 2005, Volume: 19, Issue:2 Topics: Acetamides; Azabicyclo Compounds; Benzodiazepines; Drug Costs; Humans; Hypnotics and Sedatives; Piperazines; Pyridines; Pyrimidines; Sleep Initiation and Maintenance Disorders; Zolpidem	2005
Short-term treatment with hypnotic drugs for insomnia: going beyond the evidence. Journal of psychopharmacology (Oxford, England), 2005, Volume: 19, Issue:2 Topics: Acetamides; Azabicyclo Compounds; Benzodiazepines; Cost-Benefit Analysis; Evidence-Based Medicine; Humans; Hypnotics and Sedatives; Meta-Analysis as Topic; Piperazines; Pyridines; Pyrimidines; Sleep Initiation and Maintenance Disorders; Zolpidem	2005
A NICE missed opportunity? Journal of psychopharmacology (Oxford, England), 2005, Volume: 19, Issue:2 Topics: Acetamides; Azabicyclo Compounds; Benzodiazepines; Drug Tolerance; Humans; Hypnotics and Sedatives; Piperazines; Pyridines; Pyrimidines; Sleep Initiation and Maintenance Disorders; Substance-Related Disorders; Zolpidem	2005
Consultation corner. Are the new sleep aids right for you? The Johns Hopkins medical letter health after 50, 2006, Volume: 18, Issue:2 Topics: Acetamides; Azabicyclo Compounds; Humans; Hypnotics and Sedatives; Indenes; Piperazines; Pyridines; Pyrimidines; Sleep Initiation and Maintenance Disorders; Zolpidem	2006
Meds and the restless search for sleep. Health news (Waltham, Mass.), 2006, Volume: 12, Issue:4 Topics: Acetamides; Aged; Azabicyclo Compounds; Humans; Hypnotics and Sedatives; Piperazines; Pyridines; Pyrimidines; Sleep Initiation and Maintenance Disorders; Treatment Outcome; Zolpidem	2006
Fast gas chromatography-negative-ion chemical ionization mass spectrometry with microscale volume sample preparation for the determination of benzodiazepines and alpha-hydroxy metabolites, zaleplon and zopiclone in whole blood. Journal of mass spectrometry : JMS, 2006, Volume: 41, Issue:6 Topics: Acetamides; Azabicyclo Compounds; Benzodiazepines; Blood Chemical Analysis; Gas Chromatography-Mass Spectrometry; Humans; Microchemistry; Piperazines; Pyrimidines; Reproducibility of Results; Sensitivity and Specificity; Specimen Handling; Spectrometry, Mass, Electrospray Ionization; Substance Abuse Detection; Time Factors	2006
Sedative hypnotic use in Alberta. Canadian journal of psychiatry. Revue canadienne de psychiatrie, 2006, Volume: 51, Issue:5 Topics: Acetamides; Adolescent; Adult; Anxiety Disorders; Azabicyclo Compounds; Canada; Catchment Area, Health; Drug Therapy; Female; Humans; Hypnotics and Sedatives; Male; Mental Disorders; Middle Aged; Periodicity; Piperazines; Pyrimidines	2006
[Are z-hypnotics better and safer sleeping pills than benzodiazepines?]. Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 2006, Nov-16, Volume: 126, Issue:22 Topics: Acetamides; Azabicyclo Compounds; Benzodiazepines; Half-Life; Humans; Hypnotics and Sedatives; Piperazines; Pyridines; Pyrimidines; Substance-Related Disorders; Zolpidem	2006
GPs' attitudes to benzodiazepine and 'Z-drug' prescribing: a barrier to implementation of evidence and guidance on hypnotics. The British journal of general practice : the journal of the Royal College of General Practitioners, 2006, Volume: 56, Issue:533 Topics: Acetamides; Adult; Aged; Attitude of Health Personnel; Azabicyclo Compounds; Benzodiazepines; Cross-Sectional Studies; England; Family Practice; Female; Humans; Hypnotics and Sedatives; Male; Middle Aged; Piperazines; Practice Guidelines as Topic; Practice Patterns, Physicians'; Pyridines; Pyrimidines; Surveys and Questionnaires; Zolpidem	2006
Commentary on a critique for the Journal of Psychopharmacology: NICE--excellence or eccentricity? Reflections on the z-drugs as hypnotics review. Journal of psychopharmacology (Oxford, England), 2007, Volume: 21, Issue:1 Topics: Acetamides; Azabicyclo Compounds; Benzodiazepines; Humans; Hypnotics and Sedatives; Piperazines; Practice Guidelines as Topic; Pyridines; Pyrimidines; Sleep; Sleep Initiation and Maintenance Disorders; United Kingdom; Zolpidem	2007
Magic bullets for insomnia? Patients' use and experiences of newer (Z drugs) versus older (benzodiazepine) hypnotics for sleep problems in primary care. The British journal of general practice : the journal of the Royal College of General Practitioners, 2008, Volume: 58, Issue:551 Topics: Acetamides; Adolescent; Adult; Aged; Aged, 80 and over; Attitude to Health; Azabicyclo Compounds; Benzodiazepines; Cross-Sectional Studies; Female; Humans; Hypnotics and Sedatives; Male; Middle Aged; Patient Satisfaction; Piperazines; Pyridines; Pyrimidines; Sleep Initiation and Maintenance Disorders; Substance Withdrawal Syndrome; Zolpidem	2008
Development of a homogeneous immunoassay for the detection of zolpidem in urine. Journal of analytical toxicology, 2009, Volume: 33, Issue:8 Topics: Acetamides; Azabicyclo Compounds; Chromatography, High Pressure Liquid; Cross Reactions; Enzyme Multiplied Immunoassay Technique; Humans; Hypnotics and Sedatives; Piperazines; Predictive Value of Tests; Pyridines; Pyrimidines; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization; Substance Abuse Detection; Tandem Mass Spectrometry; Zolpidem	2009
Effect of hypnotic drugs on body balance and standing steadiness. Sleep medicine reviews, 2010, Volume: 14, Issue:4 Topics: Acetamides; Adult; Aged; Alcohol Drinking; Azabicyclo Compounds; Benzodiazepines; Chronic Disease; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Drug Interactions; Humans; Hypnotics and Sedatives; Piperazines; Postural Balance; Pyridines; Pyrimidines; Randomized Controlled Trials as Topic; Sleep Initiation and Maintenance Disorders; Zolpidem	2010
Long-term use of zopiclone, zolpidem and zaleplon among Danish elderly and the association with sociodemographic factors and use of other drugs. Pharmacoepidemiology and drug safety, 2011, Volume: 20, Issue:4 Topics: Acetamides; Age Factors; Aged; Aged, 80 and over; Azabicyclo Compounds; Denmark; Female; Follow-Up Studies; Humans; Hypnotics and Sedatives; Logistic Models; Male; Piperazines; Pyridines; Pyrimidines; Registries; Sex Factors; Socioeconomic Factors; Time Factors; Zolpidem	2011
Are hypnotic benzodiazepine receptor agonists teratogenic in humans? Journal of clinical psychopharmacology, 2011, Volume: 31, Issue:3 Topics: Abnormalities, Drug-Induced; Acetamides; Adult; Azabicyclo Compounds; Congenital Abnormalities; Female; GABA-A Receptor Agonists; Humans; Hypnotics and Sedatives; Infant, Newborn; Male; Middle Aged; Parturition; Piperazines; Pregnancy; Pyridines; Pyrimidines; Registries; Sweden; Zolpidem	2011
Ultra high performance liquid chromatographic-tandem mass spectrometric multi-analyte procedure for target screening and quantification in human blood plasma: validation and application for 31 neuroleptics, 28 benzodiazepines, and Z-drugs. Analytical and bioanalytical chemistry, 2011, Volume: 401, Issue:4 Topics: Acetamides; Antipsychotic Agents; Azabicyclo Compounds; Benzodiazepines; Blood Chemical Analysis; Chromatography, High Pressure Liquid; Humans; Hypnotics and Sedatives; Limit of Detection; Piperazines; Pyridines; Pyrimidines; Tandem Mass Spectrometry; Zolpidem	2011
Insomnia: evidence-based approaches to assessment and management. Clinical medicine (London, England), 2011, Volume: 11, Issue:3 Topics: Acetamides; Azabicyclo Compounds; Cognitive Behavioral Therapy; Evidence-Based Medicine; Humans; Hypnotics and Sedatives; Patient Education as Topic; Piperazines; Practice Guidelines as Topic; Pyridines; Pyrimidines; Quality of Life; Risk Assessment; Risk Factors; Sleep Initiation and Maintenance Disorders; Treatment Outcome; Zolpidem	2011
Hypnotic prescription without face to face contact: a report from French family medicine. The European journal of general practice, 2013, Volume: 19, Issue:3 Topics: Acetamides; Adolescent; Adult; Aged; Azabicyclo Compounds; Cohort Studies; Databases, Factual; Family Practice; Female; France; Guideline Adherence; Humans; Hypnotics and Sedatives; Male; Middle Aged; Piperazines; Practice Guidelines as Topic; Practice Patterns, Physicians'; Pyridines; Pyrimidines; Retrospective Studies; Time Factors; Young Adult; Zolpidem	2013
Lapses of attention as outcome measure of the on-the-road driving test. Psychopharmacology, 2014, Volume: 231, Issue:1 Topics: Acetamides; Adult; Attention; Automobile Driver Examination; Automobile Driving; Azabicyclo Compounds; Data Interpretation, Statistical; Female; Humans; Hypnotics and Sedatives; Indenes; Male; Piperazines; Pyridines; Pyrimidines; Sex Characteristics; Zolpidem	2014
Detection and quantification of benzodiazepines and Z-drugs in human whole blood, plasma, and serum samples as part of a comprehensive multi-analyte LC-MS/MS approach. Analytical and bioanalytical chemistry, 2014, Volume: 406, Issue:3 Topics: Acetamides; Azabicyclo Compounds; Benzodiazepines; Blood Chemical Analysis; Chromatography, High Pressure Liquid; Humans; Hypnotics and Sedatives; Limit of Detection; Piperazines; Plasma; Pyridines; Pyrimidines; Reference Standards; Reproducibility of Results; Serum; Spectrometry, Mass, Electrospray Ionization; Zolpidem	2014
Development of an SPE method for the determination of zaleplon and zopiclone in hemolyzed blood using fast GC with negative-ion chemical ionization MS. Journal of separation science, 2014, Volume: 37, Issue:5 Topics: Acetamides; Azabicyclo Compounds; Gas Chromatography-Mass Spectrometry; Humans; Hypnotics and Sedatives; Piperazines; Pyrimidines; Solid Phase Extraction	2014
Misuse of benzodiazepines and Z-drugs in the UK. The British journal of psychiatry : the journal of mental science, 2014, Volume: 205, Issue:5 Topics: Acetamides; Adolescent; Adult; Anxiety; Azabicyclo Compounds; Benzodiazepines; Female; Humans; Hypnotics and Sedatives; Male; Middle Aged; Piperazines; Prescription Drug Misuse; Pyridines; Pyrimidines; Sleep Initiation and Maintenance Disorders; Surveys and Questionnaires; Young Adult; Zolpidem	2014
Benzodiazepines and Z-drug use among HIV-infected patients in Taiwan: a 13-year nationwide cohort study. BioMed research international, 2015, Volume: 2015 Topics: Acetamides; Adult; Anti-HIV Agents; Azabicyclo Compounds; Benzodiazepines; Case-Control Studies; Cohort Studies; Demography; Female; HIV Infections; Humans; Male; Piperazines; Pyridines; Pyrimidines; Taiwan; Zolpidem	2015
Benzodiazepine and "Z-Drug" Dependence: Data From a Tertiary Care Center. The primary care companion for CNS disorders, 2017, Feb-16, Volume: 19, Issue:1 Topics: Acetamides; Adult; Azabicyclo Compounds; Bacterial Proteins; Benzodiazepines; Female; Humans; Hypnotics and Sedatives; India; Male; Mental Disorders; Piperazines; Prescription Drug Misuse; Pyridines; Pyrimidines; Substance-Related Disorders; Tertiary Care Centers; Unemployment; Zolpidem	2017
An Insight into Z-Drug Abuse and Dependence: An Examination of Reports to the European Medicines Agency Database of Suspected Adverse Drug Reactions. The international journal of neuropsychopharmacology, 2019, 04-01, Volume: 22, Issue:4 Topics: Acetamides; Adolescent; Adult; Azabicyclo Compounds; Databases, Factual; Drug Misuse; Drug-Related Side Effects and Adverse Reactions; Europe; Female; Humans; Hypnotics and Sedatives; Male; Middle Aged; Pharmacovigilance; Piperazines; Pyrimidines; Substance-Related Disorders; Young Adult; Zolpidem	2019
Novel Measures of Benzodiazepine and Z-Drug Utilisation Trends in a Canadian Provincial Adult Population (2001-2016). Journal of population therapeutics and clinical pharmacology = Journal de la therapeutique des populations et de la pharmacologie clinique, 2019, 01-22, Volume: 26, Issue:1 Topics: Acetamides; Adolescent; Adult; Aged; Azabicyclo Compounds; Benzodiazepines; Canada; Drug Utilization; Female; Humans; Hypnotics and Sedatives; Male; Middle Aged; Piperazines; Practice Patterns, Physicians'; Pyrimidines; Young Adult; Zolpidem	2019
Use of short-acting and long-acting hypnotics and the risk of fracture: a critical analysis of associations in a nationwide cohort. Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2019, Volume: 30, Issue:10 Topics: Acetamides; Aged; Aged, 80 and over; Azabicyclo Compounds; Case-Control Studies; Cohort Studies; Female; Humans; Hypnotics and Sedatives; Kaplan-Meier Estimate; Male; Middle Aged; Osteoporotic Fractures; Phenothiazines; Piperazines; Pyrimidines; Registries; Risk Assessment; Sensitivity and Specificity; Sweden; Zolpidem	2019
Adverse effects of Z-drugs for sleep disturbance in people living with dementia: a population-based cohort study. BMC medicine, 2020, 11-24, Volume: 18, Issue:1 Topics: Acetamides; Aged, 80 and over; Azabicyclo Compounds; Cohort Studies; Dementia; Female; Humans; Male; Piperazines; Pyrimidines; Sleep Wake Disorders; Zolpidem	2020
The Risk of Overdose With Concomitant Use of Z-Drugs and Prescription Opioids: A Population-Based Cohort Study. The American journal of psychiatry, 2021, Volume: 178, Issue:7 Topics: Acetamides; Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Azabicyclo Compounds; Drug Overdose; Female; Humans; Hypnotics and Sedatives; Incidence; Male; Middle Aged; Piperazines; Pyrimidines; Risk; Risk Assessment; Young Adult; Zolpidem	2021
[Measurement of benzodiazepine receptor agonists metabolites and their concentration in urine]. Sudebno-meditsinskaia ekspertiza, 2023, Volume: 66, Issue:1 Topics: Clobazam; Hypnotics and Sedatives; Oxides; Receptors, GABA-A	2023