Page last updated: 2024-08-22

zalcitabine and cytidine triphosphate

zalcitabine has been researched along with cytidine triphosphate in 20 studies

Research

Studies (20)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	2 (10.00)	18.2507
2000's	18 (90.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Borroto-Esoda, K; Furman, PA; Hopkins, S; Liotta, DC; Martin, JL; Painter, G; Wilson, JE	1
Casabianca, A; Chiarantini, L; Magnani, M; Rossi, L; Schiavano, GF; Serafini, S; Vallanti, G	1
Klarmann, GJ; North, TW; Preston, BD; Schinazi, RF; Smith, RA	1
Copeland, WC; Lim, SE	1
Anderson, KS; Feng, JY; Johnson, AA; Johnson, KA	1
Emm, T; Gallagher, K; Geleziunas, R; Li, Y; Olah, T; Shi, G; Unger, S; Wu, JT	1
Anderson, KS	1
Anderson, KS; Murakami, E; Peterson, CN; Ray, AS; Schinazi, RF; Shi, J	1
Erickson-Viitanen, S; Fish, B; Gallagher, K; Geleziunas, R; King, RW; Klabe, R; Otto, MJ; Schinazi, RF; Shi, G; Unger, S; Wu, JT	1
Bacheler, L; Erickson-Viitanen, S; Gallagher, K; Garber, S; Geleziunas, R; Otto, MJ; Schinazi, RF; Shi, G; Wu, JT; Zhang, H	1
James, JS	1
Almond, MR; Liotta, DC; Mao, S; Painter, GR	1
Otto, MJ	1
Beard, A; Cartee, L; De La Rosa, A; Kravec, I; McBrayer, TR; Murphy, RL; Otto, MJ; Schinazi, RF; Schürmann, D; Stuyver, LJ	1
Sax, PE	1
Nelson, MR; Waters, L	1
Bazmi, HZ; Chu, CK; Hammond, JL; Koontz, DL; Mellors, JW; Parikh, UM; Schinazi, RF; Schlueter-Wirtz, S	1
Feinberg, J	1
Eklund, H; Mikkelsen, NE; Munch-Petersen, B	1

Reviews

4 review(s) available for zalcitabine and cytidine triphosphate

Article	Year
Perspectives on the molecular mechanism of inhibition and toxicity of nucleoside analogs that target HIV-1 reverse transcriptase. Biochimica et biophysica acta, 2002, Jul-18, Volume: 1587, Issue:2-3 Topics: Anti-HIV Agents; Cytidine Triphosphate; Deoxycytosine Nucleotides; Dideoxynucleotides; DNA Polymerase gamma; DNA-Directed DNA Polymerase; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Nucleosides; Reverse Transcriptase Inhibitors; Stereoisomerism; Zalcitabine	2002
Biochemical and mechanistic basis for the activity of nucleoside analogue inhibitors of HIV reverse transcriptase. Current topics in medicinal chemistry, 2004, Volume: 4, Issue:10 Topics: Adenine; Cytidine Triphosphate; Deoxycytidine; Deoxycytidine Monophosphate; Deoxyribonucleotides; Dioxolanes; DNA, Viral; Emtricitabine; HIV Infections; HIV Reverse Transcriptase; Humans; Kinetics; Molecular Structure; Nucleosides; Organophosphonates; Organophosphorus Compounds; Phosphorylation; Protein Binding; Protein Conformation; Purine Nucleosides; Reverse Transcriptase Inhibitors; Substrate Specificity; Tenofovir; Zalcitabine	2004
New nucleoside reverse transcriptase inhibitors for the treatment of HIV infections. Current opinion in pharmacology, 2004, Volume: 4, Issue:5 Topics: Animals; Anti-HIV Agents; Clinical Trials as Topic; Cytidine Triphosphate; Deoxycytidine; Dideoxynucleosides; Dioxolanes; Emtricitabine; HIV Infections; Humans; Purine Nucleosides; Reverse Transcriptase Inhibitors; Thionucleosides; Zalcitabine	2004
New drugs. HIV medicine, 2005, Volume: 6, Issue:4 Topics: Anti-HIV Agents; Benzophenones; Cytidine Triphosphate; Darunavir; Deoxycytidine; Emtricitabine; HIV; HIV Fusion Inhibitors; HIV Reverse Transcriptase; Humans; Imidazoles; Nitriles; Protease Inhibitors; Pyridazines; Pyridines; Pyrimidines; Pyrones; Reverse Transcriptase Inhibitors; Sulfonamides; Sulfur Compounds; Zalcitabine	2005

Trials

2 trial(s) available for zalcitabine and cytidine triphosphate

Article	Year
Potent antiviral effect of reverset in HIV-1-infected adults following a single oral dose. Antiviral therapy, 2004, Volume: 9, Issue:4 Topics: Administration, Oral; Adolescent; Adult; Cohort Studies; Cytidine Triphosphate; Dose-Response Relationship, Drug; Drug Administration Schedule; Genotype; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Middle Aged; Reverse Transcriptase Inhibitors; Sequence Analysis, RNA; Viral Load; Zalcitabine	2004
Meeting notes from the 3rd IAS Conference. New drugs. AIDS clinical care, 2005, Volume: 17, Issue:10 Topics: Brazil; CCR5 Receptor Antagonists; Congresses as Topic; Cytidine Triphosphate; Darunavir; HIV Infections; Reverse Transcriptase Inhibitors; Sulfonamides; Zalcitabine	2005

Article

Year

Potent antiviral effect of reverset in HIV-1-infected adults following a single oral dose.

Antiviral therapy, 2004, Volume: 9, Issue:4

Topics: Administration, Oral; Adolescent; Adult; Cohort Studies; Cytidine Triphosphate; Dose-Response Relationship, Drug; Drug Administration Schedule; Genotype; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Middle Aged; Reverse Transcriptase Inhibitors; Sequence Analysis, RNA; Viral Load; Zalcitabine

2004

Meeting notes from the 3rd IAS Conference. New drugs.

AIDS clinical care, 2005, Volume: 17, Issue:10

Topics: Brazil; CCR5 Receptor Antagonists; Congresses as Topic; Cytidine Triphosphate; Darunavir; HIV Infections; Reverse Transcriptase Inhibitors; Sulfonamides; Zalcitabine

2005

Other Studies

14 other study(ies) available for zalcitabine and cytidine triphosphate

Article	Year
The 5'-triphosphates of the (-) and (+) enantiomers of cis-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolane-5-yl]cytosine equally inhibit human immunodeficiency virus type 1 reverse transcriptase. Antimicrobial agents and chemotherapy, 1993, Volume: 37, Issue:8 Topics: Antiviral Agents; Cytidine Triphosphate; DNA, Viral; Emtricitabine; HIV Reverse Transcriptase; HIV-1; Kinetics; Reverse Transcriptase Inhibitors; RNA, Viral; Stereoisomerism; Thiophenes; Zalcitabine	1993
Metabolism, mitochondrial uptake and toxicity of 2', 3'-dideoxycytidine. The Biochemical journal, 1999, Dec-15, Volume: 344 Pt 3 Topics: Animals; Biological Transport; Carnitine; Choline-Phosphate Cytidylyltransferase; Cytidine Diphosphate Choline; Cytidine Triphosphate; Deoxycytosine Nucleotides; Dideoxynucleotides; DNA, Mitochondrial; Humans; Kinetics; Mitochondria, Liver; Rabbits; Rhodamine 123; U937 Cells; Zalcitabine	1999
Site-specific incorporation of nucleoside analogs by HIV-1 reverse transcriptase and the template grip mutant P157S. Template interactions influence substrate recognition at the polymerase active site. The Journal of biological chemistry, 2000, Jan-07, Volume: 275, Issue:1 Topics: Catalytic Domain; Cytidine Triphosphate; Dideoxynucleotides; Dose-Response Relationship, Drug; Drug Resistance; HIV Reverse Transcriptase; HIV-1; Lamivudine; Mutation; Proline; Reverse Transcriptase Inhibitors; Thionucleosides; Thiophenes; Thymine Nucleotides; Transcription, Genetic; Zalcitabine; Zidovudine	2000
Differential incorporation and removal of antiviral deoxynucleotides by human DNA polymerase gamma. The Journal of biological chemistry, 2001, Jun-29, Volume: 276, Issue:26 Topics: Anti-HIV Agents; Cytidine Triphosphate; Deoxyguanine Nucleotides; Deoxyribonucleotides; Dideoxynucleotides; DNA; DNA Polymerase gamma; DNA Replication; DNA-Directed DNA Polymerase; Exodeoxyribonucleases; Humans; Kinetics; Lamivudine; Nucleic Acid Synthesis Inhibitors; Reverse Transcriptase Inhibitors; Stavudine; Substrate Specificity; Thymine Nucleotides; Zalcitabine; Zidovudine	2001
Insights into the molecular mechanism of mitochondrial toxicity by AIDS drugs. The Journal of biological chemistry, 2001, Jun-29, Volume: 276, Issue:26 Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Cytidine Triphosphate; Deoxycytosine Nucleotides; Dideoxynucleotides; DNA; DNA Polymerase gamma; DNA Replication; DNA-Directed DNA Polymerase; DNA, Mitochondrial; Exodeoxyribonucleases; Humans; Kinetics; Lamivudine; Mitochondria; Nucleic Acid Synthesis Inhibitors; Reverse Transcriptase Inhibitors; Zalcitabine	2001
Novel direct detection method for quantitative determination of intracellular nucleoside triphosphates using weak anion exchange liquid chromatography/tandem mass spectrometry. Rapid communications in mass spectrometry : RCM, 2002, Volume: 16, Issue:11 Topics: Chromatography, Liquid; Cytidine Triphosphate; Deoxycytidine; Mass Spectrometry; Monocytes; Reverse Transcriptase Inhibitors; Zalcitabine	2002
Interactions of enantiomers of 2',3'-didehydro-2',3'-dideoxy-fluorocytidine with wild type and M184V mutant HIV-1 reverse transcriptase. Antiviral research, 2002, Volume: 56, Issue:3 Topics: Base Sequence; Binding Sites; Cytidine Triphosphate; Deoxycytosine Nucleotides; HIV Reverse Transcriptase; Kinetics; Models, Molecular; Molecular Sequence Data; Point Mutation; Reverse Transcriptase Inhibitors; Stereoisomerism; Zalcitabine	2002
Cellular pharmacology of D-d4FC, a nucleoside analogue active against drug-resistant HIV. Antiviral chemistry & chemotherapy, 2003, Volume: 14, Issue:1 Topics: Anti-HIV Agents; Cells, Cultured; Cytidine Triphosphate; Drug Interactions; Drug Resistance, Viral; HIV Protease Inhibitors; HIV Reverse Transcriptase; HIV-1; Humans; Intracellular Membranes; Leukocytes, Mononuclear; Nucleosides; Phosphorylation; Phytohemagglutinins; Reverse Transcriptase Inhibitors; Zalcitabine	2003
HIV-1 resistance profile of the novel nucleoside reverse transcriptase inhibitor beta-D-2',3'-dideoxy-2',3'-didehydro-5-fluorocytidine (Reverset). Antiviral chemistry & chemotherapy, 2003, Volume: 14, Issue:1 Topics: Adenine; Anti-HIV Agents; Cell Line; Cytidine Triphosphate; Didanosine; Drug Resistance, Multiple, Viral; Genotype; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Mutation; Organophosphonates; Organophosphorus Compounds; Reverse Transcriptase Inhibitors; Species Specificity; Tenofovir; Transfection; Zalcitabine; Zidovudine	2003
Antiretroviral pipeline: new-drug reports from retroviruses conference. AIDS treatment news, 2004, Feb-27, Issue:398 Topics: Anti-HIV Agents; CCR5 Receptor Antagonists; Cytidine Triphosphate; Drug Resistance, Viral; HIV; HIV Fusion Inhibitors; Membrane Fusion; Zalcitabine	2004
Meeting notes from ICAAC. D-D4FC (Reverset): further data on treatment-experienced patients. AIDS clinical care, 2005, Volume: 17, Issue:1 Topics: Anti-HIV Agents; Cytidine Triphosphate; HIV Infections; Humans; Mutation; Viral Load; Zalcitabine	2005
In vitro selection and analysis of human immunodeficiency virus type 1 resistant to derivatives of beta-2',3'-didehydro-2',3'-dideoxy-5-fluorocytidine. Antimicrobial agents and chemotherapy, 2005, Volume: 49, Issue:9 Topics: Amino Acid Substitution; Anti-HIV Agents; Cell Line; Cytidine Triphosphate; Drug Resistance, Viral; HIV Reverse Transcriptase; HIV-1; Humans; Mutagenesis, Site-Directed; Mutation; Reverse Transcriptase Inhibitors; Stereoisomerism; Structure-Activity Relationship; Zalcitabine	2005
dD4FC development discontinued. AIDS clinical care, 2006, Volume: 18, Issue:5 Topics: Cytidine Triphosphate; Drug Industry; HIV Infections; Humans; Hyperlipidemias; Reverse Transcriptase Inhibitors; Zalcitabine	2006
Structural studies of nucleoside analog and feedback inhibitor binding to Drosophila melanogaster multisubstrate deoxyribonucleoside kinase. The FEBS journal, 2008, Volume: 275, Issue:9 Topics: Adenosine Diphosphate; Animals; Antimetabolites; Bromodeoxyuridine; Cytarabine; Cytidine Triphosphate; Drosophila melanogaster; Drosophila Proteins; Feedback; Floxuridine; Guanosine Triphosphate; Hydrogen Bonding; Inhibitory Concentration 50; Kinetics; Models, Chemical; Models, Molecular; Phosphotransferases (Alcohol Group Acceptor); Protein Binding; Protein Structure, Secondary; Structure-Activity Relationship; Thymine Nucleotides; X-Ray Diffraction; Zalcitabine; Zidovudine	2008