Compounds > zacopride
Page last updated: 2024-09-02

zacopride and prazosin

zacopride has been researched along with prazosin in 3 studies

Compound Research Comparison

Studies
(zacopride)		Trials
(zacopride)		Recent Studies (post-2010)
(zacopride)		Studies
(prazosin)		Trials
(prazosin)		Recent Studies (post-2010) (prazosin)
1804167,914713682

Protein Interaction Comparison

ProteinTaxonomyzacopride (IC50)prazosin (IC50)
Solute carrier family 22 member 1 Homo sapiens (human)5.87
Interstitial collagenaseHomo sapiens (human)4.036
Alpha-2A adrenergic receptorHomo sapiens (human)2.638
Matrix metalloproteinase-9Homo sapiens (human)6.963
Alpha-1B adrenergic receptorRattus norvegicus (Norway rat)0.0008
Ribosyldihydronicotinamide dehydrogenase [quinone]Homo sapiens (human)0.0078
Alpha-2B adrenergic receptorHomo sapiens (human)0.29
Alpha-2C adrenergic receptorHomo sapiens (human)0.647
Alpha-1D adrenergic receptorRattus norvegicus (Norway rat)0.0008
Alpha-1D adrenergic receptorHomo sapiens (human)0.0007
Bromodomain-containing protein 2Homo sapiens (human)0.0009
Alpha-1A adrenergic receptorHomo sapiens (human)0.0006
Alpha-1B adrenergic receptorHomo sapiens (human)0.0006
5-hydroxytryptamine receptor 2BHomo sapiens (human)4.118
Alpha-1A adrenergic receptorRattus norvegicus (Norway rat)0.0008
5-hydroxytryptamine receptor 7Cavia porcellus (domestic guinea pig)9.9
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)1.5849
Multidrug and toxin extrusion protein 1Homo sapiens (human)1.6

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (66.67)18.2507
2000's0 (0.00)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bandyopadhyaya, A; Rajagopalan, DR; Rajagopalan, P; Rajagopalan, R1
Ito, T; Kii, Y1
Barnes, JM; Barnes, NM; Ge, J; Towers, P1

Other Studies

3 other study(ies) available for zacopride and prazosin

ArticleYear
The synthesis and comparative receptor binding affinities of novel, isomeric pyridoindolobenzazepine scaffolds.
    Bioorganic & medicinal chemistry letters, 2014, Jan-15, Volume: 24, Issue:2

    Topics: Benzodiazepinones; Isomerism; Protein Binding; Protein Structure, Tertiary; Receptors, Cell Surface

2014
Effects of 5-HT4-receptor agonists, cisapride, mosapride citrate, and zacopride, on cardiac action potentials in guinea pig isolated papillary muscles.
    Journal of cardiovascular pharmacology, 1997, Volume: 29, Issue:5

    Topics: Action Potentials; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Anti-Arrhythmia Agents; Benzamides; Bridged Bicyclo Compounds, Heterocyclic; Cisapride; Electric Stimulation; Electrocardiography; Guinea Pigs; Heart; In Vitro Techniques; Male; Microelectrodes; Morpholines; Muscle, Smooth, Vascular; Papillary Muscles; Piperidines; Prazosin; Quaternary Ammonium Compounds; Serotonin Antagonists; Serotonin Receptor Agonists; Sympathetic Nervous System

1997
Distribution of S(-)-zacopride-insensitive [125I]R(+)-zacopride binding sites in the rat brain and peripheral tissues.
    European journal of pharmacology, 1997, Aug-13, Volume: 332, Issue:3

    Topics: Animals; Autoradiography; Benzamides; Binding, Competitive; Brain; Bridged Bicyclo Compounds, Heterocyclic; In Vitro Techniques; Iodine Radioisotopes; Male; Mianserin; Prazosin; Protein Binding; Radioligand Assay; Rats; Rats, Wistar; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Serotonin; Serotonin Antagonists; Stereoisomerism; Sulpiride; Tissue Distribution

1997