zacopride has been researched along with mianserin in 4 studies
| Studies (zacopride) | Trials (zacopride) | Recent Studies (post-2010) (zacopride) | Studies (mianserin) | Trials (mianserin) | Recent Studies (post-2010) (mianserin) |
|---|---|---|---|---|---|
| 180 | 4 | 16 | 2,624 | 539 | 488 |
| Protein | Taxonomy | zacopride (IC50) | mianserin (IC50) |
|---|---|---|---|
| 5-hydroxytryptamine receptor 3E | Homo sapiens (human) | 1.4125 | |
| 5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | 0.0012 | |
| 5-hydroxytryptamine receptor 3B | Homo sapiens (human) | 1.4125 | |
| Aldo-keto reductase family 1 member B1 | Rattus norvegicus (Norway rat) | 0.163 | |
| Muscarinic acetylcholine receptor M2 | Homo sapiens (human) | 1.078 | |
| Muscarinic acetylcholine receptor M4 | Homo sapiens (human) | 2.066 | |
| 5-hydroxytryptamine receptor 1A | Homo sapiens (human) | 0.3981 | |
| Muscarinic acetylcholine receptor M5 | Rattus norvegicus (Norway rat) | 1.9 | |
| Muscarinic acetylcholine receptor M5 | Homo sapiens (human) | 0.32 | |
| Alpha-2A adrenergic receptor | Homo sapiens (human) | 0.0213 | |
| Muscarinic acetylcholine receptor M1 | Homo sapiens (human) | 1.423 | |
| D(2) dopamine receptor | Homo sapiens (human) | 7.0795 | |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | 0.38 | |
| Alpha-2B adrenergic receptor | Homo sapiens (human) | 0.026 | |
| Alpha-2C adrenergic receptor | Homo sapiens (human) | 0.0661 | |
| 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | 0.872 | |
| Alpha-2B adrenergic receptor | Rattus norvegicus (Norway rat) | 0.21 | |
| Muscarinic acetylcholine receptor M3 | Homo sapiens (human) | 1.405 | |
| D(1A) dopamine receptor | Homo sapiens (human) | 0.543 | |
| D(4) dopamine receptor | Homo sapiens (human) | 3.3113 | |
| Alpha-2C adrenergic receptor | Rattus norvegicus (Norway rat) | 0.21 | |
| Alpha-2A adrenergic receptor | Rattus norvegicus (Norway rat) | 0.21 | |
| Alpha-1D adrenergic receptor | Rattus norvegicus (Norway rat) | 0.38 | |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | 0.163 | |
| 5-hydroxytryptamine receptor 3A | Mus musculus (house mouse) | 1.4125 | |
| Histamine H2 receptor | Homo sapiens (human) | 1.008 | |
| Alpha-1D adrenergic receptor | Homo sapiens (human) | 0.083 | |
| Endothelin-1 receptor | Homo sapiens (human) | 0.1148 | |
| 5-hydroxytryptamine receptor 1D | Homo sapiens (human) | 0.3802 | |
| 5-hydroxytryptamine receptor 2A | Homo sapiens (human) | 0.011 | |
| 5-hydroxytryptamine receptor 2C | Homo sapiens (human) | 0.0043 | |
| 5-hydroxytryptamine receptor 1B | Rattus norvegicus (Norway rat) | 0.872 | |
| Sodium-dependent serotonin transporter | Homo sapiens (human) | 2.068 | |
| Sodium-dependent serotonin transporter | Rattus norvegicus (Norway rat) | 2.9 | |
| 5-hydroxytryptamine receptor 7 | Homo sapiens (human) | 0.1148 | |
| Alpha-1A adrenergic receptor | Homo sapiens (human) | 0.4074 | |
| Type-2 angiotensin II receptor | Rattus norvegicus (Norway rat) | 0.21 | |
| Histamine H1 receptor | Homo sapiens (human) | 0.0024 | |
| D(3) dopamine receptor | Homo sapiens (human) | 3.8905 | |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | 0.0073 | |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | 0.19 | |
| 5-hydroxytryptamine receptor 3A | Homo sapiens (human) | 1.4125 | |
| Histamine H2 receptor | Cavia porcellus (domestic guinea pig) | 0.88 | |
| 5-hydroxytryptamine receptor 6 | Homo sapiens (human) | 0.085 | |
| D(2) dopamine receptor | Rattus norvegicus (Norway rat) | 3.5481 | |
| 5-hydroxytryptamine receptor 3D | Homo sapiens (human) | 1.4125 | |
| 5-hydroxytryptamine receptor 3C | Homo sapiens (human) | 1.4125 | |
| 5-hydroxytryptamine receptor 3B | Mus musculus (house mouse) | 1.4125 | |
| Transporter | Rattus norvegicus (Norway rat) | 0.022 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (75.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bryce, D; Chalabi, PM; Furman, J; Guarino, KJ; Ives, JL; McLean, S; Nagel, AA; Rosen, T; Roth, RW; Seeger, TF | 1 |
| Glennon, RA | 1 |
| Gozlan, H; Hamon, M; Kidd, FJ; Levy, JC; Nielsen, M | 1 |
| Barnes, JM; Barnes, NM; Ge, J; Towers, P | 1 |
1 review(s) available for zacopride and mianserin
| Article | Year |
|---|---|
Higher-end serotonin receptors: 5-HT(5), 5-HT(6), and 5-HT(7).
Topics: Animals; Humans; Ligands; Receptors, Serotonin; Serotonin Agents; Serotonin Antagonists; Serotonin Receptor Agonists | 2003 |
3 other study(ies) available for zacopride and mianserin
| Article | Year |
|---|---|
Synthesis, in vitro binding profile, and central nervous system penetrability of the highly potent 5-HT3 receptor antagonist [3H]-4-(2-methoxyphenyl)-2-[4(5)-methyl-5(4)-imidazolylmethyl]thiazole.
Topics: Animals; Blood-Brain Barrier; Brain; Chemical Phenomena; Chemistry; Glioma; Imidazoles; Mice; Molecular Structure; Neuroblastoma; Serotonin Antagonists; Thiazoles; Tumor Cells, Cultured | 1990 |
Characterisation of the non-5-HT3 high-affinity 'R' binding site for (R)-zacopride in brain and other tissues.
Topics: Aged; Aged, 80 and over; Animals; Benzamides; Binding Sites; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Female; Glioma; Hippocampus; Humans; Male; Mianserin; Ondansetron; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin Antagonists; Spinal Cord; Stereoisomerism; Tissue Distribution; Tumor Cells, Cultured | 1993 |
Distribution of S(-)-zacopride-insensitive [125I]R(+)-zacopride binding sites in the rat brain and peripheral tissues.
Topics: Animals; Autoradiography; Benzamides; Binding, Competitive; Brain; Bridged Bicyclo Compounds, Heterocyclic; In Vitro Techniques; Iodine Radioisotopes; Male; Mianserin; Prazosin; Protein Binding; Radioligand Assay; Rats; Rats, Wistar; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Serotonin; Serotonin Antagonists; Stereoisomerism; Sulpiride; Tissue Distribution | 1997 |