zacopride has been researched along with granisetron in 17 studies
| Studies (zacopride) | Trials (zacopride) | Recent Studies (post-2010) (zacopride) | Studies (granisetron) | Trials (granisetron) | Recent Studies (post-2010) (granisetron) |
|---|---|---|---|---|---|
| 180 | 4 | 16 | 59 | 0 | 16 |
| 180 | 4 | 16 | 1,149 | 466 | 243 |
| Protein | Taxonomy | zacopride (IC50) | granisetron (IC50) |
|---|---|---|---|
| Solute carrier family 22 member 2 | Homo sapiens (human) | 4.3 | |
| D | Rattus norvegicus (Norway rat) | 3.8019 | |
| Alpha-2B adrenergic receptor | Rattus norvegicus (Norway rat) | 3.8019 | |
| Alpha-2C adrenergic receptor | Rattus norvegicus (Norway rat) | 3.8019 | |
| Alpha-2A adrenergic receptor | Rattus norvegicus (Norway rat) | 3.8019 | |
| Sodium-dependent dopamine transporter | Rattus norvegicus (Norway rat) | 3.8019 | |
| 5-hydroxytryptamine receptor 3A | Rattus norvegicus (Norway rat) | 1.76 | |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | 3.7702 | |
| Multidrug and toxin extrusion protein 1 | Homo sapiens (human) | 5 | |
| 5-hydroxytryptamine receptor 3B | Rattus norvegicus (Norway rat) | 1.76 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (11.76) | 18.7374 |
| 1990's | 14 (82.35) | 18.2507 |
| 2000's | 1 (5.88) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Airey, JE; Campbell, HF; Darkes, P; Fitzpatrick, LR; Klein, S; Neuenschwander, K; Pendley, CE; Powers, M; Schnapper, M; Youssefyeh, RD | 1 |
| Airey, JE; Campbell, HF; Golec, S; Klein, S; Powers, M; Rodriguez, W; Schnapper, M; Studt, W; Woodward, R; Youssefyeh, RD | 1 |
| Bloomquist, W; Cohen, ML; Reid, LR; Robertson, DW; Schenck, K; Wong, DT | 1 |
| Barnes, NM; Cheng, CH; Costall, B; Ge, J; Kelly, ME; Naylor, RJ | 1 |
| Andrews, PL; Bhandari, P | 1 |
| Gandara, DR; Hesketh, PJ | 1 |
| Barnes, NM; Costall, B; Kelly, ME; Naylor, RJ; Onaivi, ES | 1 |
| Costall, B; Domeney, AM; Naylor, RJ | 1 |
| King, GL | 1 |
| File, SE; Johnston, AL | 1 |
| Barnes, NM; Costall, B; Naylor, RJ; Tattersall, FD | 1 |
| Anthony, EW; Nevins, ME | 1 |
| Daniels, S; Eglen, RM; Fontana, DJ; Khabbaz, M; Kilfoil, T; Lee, CH; Wong, EH | 1 |
| Barnes, JM; Barnes, NM | 1 |
| Kawakita, T; Kuroita, T; Sakamori, M | 1 |
| Dahl, SG; Junien, JL; Langlois, A; Pascaud, X; Rivière, PJ | 1 |
| Imazumi, K; Matsui, S; Matsuo, M; Mutoh, S; Nakayama, H; Yamakuni, H | 1 |
17 other study(ies) available for zacopride and granisetron
| Article | Year |
|---|---|
Development of high-affinity 5-HT3 receptor antagonists. 1. Initial structure-activity relationship of novel benzamides.
Topics: Animals; Antiemetics; Benzamides; Benzofurans; Binding, Competitive; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Cisplatin; Ferrets; Granisetron; Imidazoles; Indazoles; Indoles; Male; Metoclopramide; Molecular Structure; Ondansetron; Rats; Receptors, Serotonin; Serotonin Antagonists; Structure-Activity Relationship; Vomiting | 1992 |
Development of high-affinity 5-HT3 receptor antagonists. 2. Two novel tricyclic benzamides.
Topics: Amides; Animals; Antiemetics; Benzamides; Benzofurans; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Cisplatin; Dogs; Ferrets; Guinea Pigs; Ileum; Molecular Structure; Muscle Contraction; Rats; Serotonin; Serotonin Antagonists; Structure-Activity Relationship; Vomiting; X-Ray Diffraction | 1992 |
Synthesis and biochemical evaluation of tritium-labeled 1-methyl-N-(8-methyl-8-azabicyclo[3.2.1]oct-3-yl)-1H-indazole-3-carboxa mide, a useful radioligand for 5HT3 receptors.
Topics: Animals; Cell Membrane; Cerebral Cortex; Guinea Pigs; Heart Rate; Ileum; Indazoles; Male; Methylation; Myocardium; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Structure-Activity Relationship; Tritium; Tropanes | 1990 |
Profiles of interaction of R(+)/S(-)-zacopride and anxiolytic agents in a mouse model.
Topics: Animals; Anti-Anxiety Agents; Antiemetics; Behavior, Animal; Benzamides; Brain Chemistry; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chlordiazepoxide; Fenclonine; Granisetron; Indazoles; Male; Mice; Neurotransmitter Agents; Ondansetron; Receptors, Cholecystokinin; Receptors, Serotonin; Ritanserin; Serotonin Antagonists; Stereoisomerism | 1992 |
Preliminary evidence for the involvement of the putative 5-HT4 receptor in zacopride- and copper sulphate-induced vomiting in the ferret.
Topics: Analysis of Variance; Animals; Antiemetics; Benzamides; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Copper; Copper Sulfate; Female; Ferrets; Granisetron; Imidazoles; Indazoles; Indoles; Loperamide; Male; Ondansetron; Receptors, Serotonin; Serotonin Antagonists; Tropisetron; Vomiting | 1991 |
Serotonin antagonists: a new class of antiemetic agents.
Topics: Antiemetics; Benzamides; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Granisetron; Humans; Imidazoles; Indazoles; Indoles; Metoclopramide; Ondansetron; Quinolizines; Receptors, Serotonin; Serotonin Antagonists; Tropanes; Tropisetron; Vomiting | 1991 |
Ketotifen and its analogues reduce aversive responding in the rodent.
Topics: Animals; Avoidance Learning; Behavior, Animal; Benzamides; Brain Chemistry; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cocaine; Diazepam; Ethanol; Exploratory Behavior; Granisetron; Indazoles; Ketotifen; Male; Mice; Mice, Inbred Strains; Nicotine; Radioligand Assay; Rats; Rats, Inbred Strains; Serotonin Antagonists; Social Behavior | 1990 |
5-HT3 receptor antagonists attenuate dopamine-induced hyperactivity in the rat.
Topics: Animals; Benzamides; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Dopamine; Dopamine Antagonists; Female; Granisetron; Indazoles; Indoles; Injections; Motor Activity; Nucleus Accumbens; Rats; Rats, Inbred Strains; Serotonin Antagonists; Tropisetron | 1990 |
Emesis and defecations induced by the 5-hydroxytryptamine (5-HT3) receptor antagonist zacopride in the ferret.
Topics: Administration, Oral; Animals; Antiemetics; Benzamides; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Bridged-Ring Compounds; Defecation; Dose-Response Relationship, Drug; Ferrets; Granisetron; Indazoles; Injections, Intravenous; Male; Metoclopramide; Pyrazoles; Serotonin; Serotonin Antagonists; Vagotomy; Vomiting | 1990 |
Lack of effects of 5HT3 receptor antagonists in the social interaction and elevated plus-maze tests of anxiety in the rat.
Topics: Animals; Anxiety; Benzamides; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chlordiazepoxide; Granisetron; Imidazoles; Indazoles; Male; Motor Activity; Ondansetron; Rats; Serotonin Antagonists; Social Behavior | 1989 |
Identification of 5-HT3 recognition sites in the ferret area postrema.
Topics: Animals; Benzamides; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Carnivora; Cerebral Ventricles; Female; Ferrets; Granisetron; In Vitro Techniques; Indazoles; Radioligand Assay; Receptors, Serotonin; Serotonin Antagonists | 1988 |
Antagonists at the serotonin-3 receptor can reduce the fear-potentiated startle response in the rat: evidence for different types of anxiolytic activity?
Topics: Animals; Anti-Anxiety Agents; Benzamides; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Buspirone; Diazepam; Fear; Granisetron; Male; Ondansetron; Rats; Reflex, Startle; Serotonin Antagonists | 1994 |
Comparison of potencies of 5-HT3 receptor antagonists at inhibiting aversive behavior to illumination and the von Bezold-Jarisch reflex in the mouse.
Topics: Animals; Behavior, Animal; Benzamides; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Dose-Response Relationship, Drug; Granisetron; Heart Rate; Lighting; Mice; Motor Activity; Ondansetron; Reflex; Serotonin Antagonists; Stereoisomerism | 1994 |
Differential binding characteristics of agonists at 5-HT3 receptor recognition sites in NG108-15 neuroblastoma-glioma cells labelled by [3H]-(S)-zacopride and [3H]granisetron.
Topics: Animals; Benzamides; Biguanides; Binding Sites; Binding, Competitive; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cell Membrane; Glioma; Granisetron; Indazoles; Kinetics; Neuroblastoma; Ondansetron; Quipazine; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Tritium | 1993 |
Design and synthesis of 6-chloro-3,4-dihydro-4-methyl-2H-1,4-benzoxazine-8-carboxamide derivatives as potent serotonin-3 (5-HT3) receptor antagonists.
Topics: Animals; Benzamides; Binding, Competitive; Blood Pressure; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Granisetron; Heart Rate; In Vitro Techniques; Male; Oxazines; Rats; Receptors, Serotonin; Reflex; Serotonin Antagonists; Stereoisomerism; Structure-Activity Relationship | 1996 |
Response heterogeneity of 5-HT3 receptor antagonists in a rat visceral hypersensitivity model.
Topics: Animals; Benzamides; Bridged Bicyclo Compounds, Heterocyclic; Colon; Granisetron; Indoles; Male; Muscle Contraction; Muscle, Smooth; Ondansetron; Pain; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Serotonin Antagonists; Tropisetron | 1996 |
Inhibitory effect of zacopride on Cisplatin-induced delayed emesis in ferrets.
Topics: Animals; Antiemetics; Antineoplastic Agents; Benzamides; Bridged Bicyclo Compounds, Heterocyclic; Cisplatin; Drug Therapy, Combination; Ferrets; Granisetron; Male; Serotonin Antagonists; Time Factors; Vomiting | 2006 |