zacopride has been researched along with 2-methyl-5-ht in 10 studies
| Studies (zacopride) | Trials (zacopride) | Recent Studies (post-2010) (zacopride) | Studies (2-methyl-5-ht) | Trials (2-methyl-5-ht) | Recent Studies (post-2010) (2-methyl-5-ht) |
|---|---|---|---|---|---|
| 180 | 4 | 16 | 219 | 0 | 15 |
| Protein | Taxonomy | zacopride (IC50) | 2-methyl-5-ht (IC50) |
|---|---|---|---|
| 5-hydroxytryptamine receptor 3A | Rattus norvegicus (Norway rat) | 0.779 | |
| 5-hydroxytryptamine receptor 3B | Rattus norvegicus (Norway rat) | 0.779 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (10.00) | 18.7374 |
| 1990's | 7 (70.00) | 18.2507 |
| 2000's | 2 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bryce, D; Chalabi, PM; Furman, J; Guarino, KJ; Ives, JL; McLean, S; Nagel, AA; Rosen, T; Roth, RW; Seeger, TF | 1 |
| Glennon, RA | 1 |
| Borrelli, G; Budriesi, R; Butini, S; Caccia, S; Cagnotto, A; Campiani, G; Catalanotti, B; Chiarini, A; Coccone, SS; Colovic, M; Fattorusso, C; Fiorini, I; Fracasso, C; Gemma, S; Hamon, M; Ioan, P; Mennini, T; Morelli, E; Nacci, V; Novellino, E; Persico, M; Ros, S | 1 |
| Glennon, RA; Young, R | 1 |
| Delarue, C; Idres, S; Lefebvre, H; Vaudry, H | 1 |
| Ashby, CR; Edwards, E; Minabe, Y; Wang, RY | 1 |
| Coffman, WJ; Cohen, ML; Wilson, H | 1 |
| King, GL | 1 |
| Barnes, JM; Barnes, NM; Costall, B; Naylor, RJ; Tyers, MB | 1 |
| Alcalde, AI; RodrÃguez-Yoldi, MC; RodrÃguez-Yoldi, MJ; Salvador, MT | 1 |
1 review(s) available for zacopride and 2-methyl-5-ht
| Article | Year |
|---|---|
Higher-end serotonin receptors: 5-HT(5), 5-HT(6), and 5-HT(7).
Topics: Animals; Humans; Ligands; Receptors, Serotonin; Serotonin Agents; Serotonin Antagonists; Serotonin Receptor Agonists | 2003 |
9 other study(ies) available for zacopride and 2-methyl-5-ht
| Article | Year |
|---|---|
Synthesis, in vitro binding profile, and central nervous system penetrability of the highly potent 5-HT3 receptor antagonist [3H]-4-(2-methoxyphenyl)-2-[4(5)-methyl-5(4)-imidazolylmethyl]thiazole.
Topics: Animals; Blood-Brain Barrier; Brain; Chemical Phenomena; Chemistry; Glioma; Imidazoles; Mice; Molecular Structure; Neuroblastoma; Serotonin Antagonists; Thiazoles; Tumor Cells, Cultured | 1990 |
Specific targeting of peripheral serotonin 5-HT(3) receptors. Synthesis, biological investigation, and structure-activity relationships.
Topics: Animals; Baroreflex; Chemical Phenomena; Female; Guinea Pigs; Heart; Heart Atria; Male; Mice; Models, Molecular; Myocardium; Pyrroles; Quinoxalines; Quipazine; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Serotonin 5-HT3 Receptor Agonists; Structure-Activity Relationship | 2009 |
Zacopride and its optical isomers produce stereoselective antagonism of a 2-methylserotonin discriminative stimulus.
Topics: Animals; Benzamides; Binding Sites; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Discrimination Learning; Male; Rats; Rats, Inbred Strains; Serotonin; Serotonin Antagonists; Stereoisomerism | 1992 |
Benzamide derivatives provide evidence for the involvement of a 5-HT4 receptor type in the mechanism of action of serotonin in frog adrenocortical cells.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenal Cortex; Adrenal Cortex Hormones; Aldosterone; Animals; Benzamides; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cisapride; Corticosterone; In Vitro Techniques; Kinetics; Methysergide; Piperidines; Rana ridibunda; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Tetrahydronaphthalenes | 1991 |
5-HT3-like receptors in the rat medial prefrontal cortex: an electrophysiological study.
Topics: Action Potentials; Animals; Benzamides; Biguanides; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Evoked Potentials; Glutamates; Glutamic Acid; Hypoglycemic Agents; Magnesium Chloride; Male; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Serotonin Antagonists | 1991 |
5-Hydroxytryptamine3 receptors mediate tachycardia in conscious instrumented dogs.
Topics: Animals; Benzamides; Blood Pressure; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Dogs; Ergolines; Heart Rate; Hexamethonium; Hexamethonium Compounds; Imidazoles; Indoles; Male; Ondansetron; Receptors, Serotonin; Serotonin; Tropisetron | 1990 |
Emesis and defecations induced by the 5-hydroxytryptamine (5-HT3) receptor antagonist zacopride in the ferret.
Topics: Administration, Oral; Animals; Antiemetics; Benzamides; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Bridged-Ring Compounds; Defecation; Dose-Response Relationship, Drug; Ferrets; Granisetron; Indazoles; Injections, Intravenous; Male; Metoclopramide; Pyrazoles; Serotonin; Serotonin Antagonists; Vagotomy; Vomiting | 1990 |
5-HT3 receptors mediate inhibition of acetylcholine release in cortical tissue.
Topics: Acetylcholine; Animals; Benzamides; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Female; Imidazoles; Metoclopramide; Ondansetron; Potassium; Rats; Receptors, Serotonin; Serotonin; Serotonin Antagonists | 1989 |
5-HT receptor subtypes involved in the serotonin-induced inhibition of L-leucine absorption in rabbit jejunum.
Topics: Animals; Benzamides; Bridged Bicyclo Compounds, Heterocyclic; Indoles; Intestinal Absorption; Jejunum; Leucine; Male; Ondansetron; Rabbits; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Receptors, Serotonin, 5-HT4; Ritanserin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Sulfonamides | 1997 |